Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-7 ERVK-21 ERVK-9 ERVK-24

1.17e-0637434GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-7 ERVK-21 ERVK-9 ERVK-24

1.30e-0638434GO:0070001
GeneOntologyMolecularFunctionprotein kinase binding

SLC12A6 PRKD2 CLASP2 CCR5 DUSP19 LRBA DSCAM VDAC1 MAPK8IP3

8.27e-05873439GO:0019901
GeneOntologyMolecularFunctionkinase binding

SLC12A6 PRKD2 CLASP2 CCR5 DUSP19 LRBA DSCAM VDAC1 MAPK8IP3

1.82e-04969439GO:0019900
GeneOntologyMolecularFunctionendopeptidase activity

OMA1 ERVK-7 ERVK-21 ERVK-9 ERVK-24 ERAP1

2.99e-04430436GO:0004175
GeneOntologyMolecularFunctiontransporter activity

VMP1 SLC12A6 SLC25A53 SLC8A1 P2RX3 SLC29A1 GJB6 TRPC3 VDAC1 SLC26A5

3.27e-0412894310GO:0005215
GeneOntologyMolecularFunctionMAP-kinase scaffold activity

DUSP19 MAPK8IP3

3.48e-0413432GO:0005078
GeneOntologyMolecularFunctionmitogen-activated protein kinase kinase binding

DUSP19 MAPK8IP3

7.57e-0419432GO:0031434
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC12A6 SLC25A53 SLC8A1 P2RX3 SLC29A1 GJB6 TRPC3 VDAC1 SLC26A5

7.75e-041180439GO:0022857
GeneOntologyMolecularFunctionmicrotubule plus-end binding

CLASP2 FBXW11

1.02e-0322432GO:0051010
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC12A6 SLC8A1 P2RX3 SLC29A1 TRPC3 VDAC1 SLC26A5

1.40e-03793437GO:0015075
GeneOntologyMolecularFunctionmitogen-activated protein kinase kinase kinase binding

DUSP19 MAPK8IP3

1.42e-0326432GO:0031435
GeneOntologyMolecularFunctionpeptidase activity

OMA1 ERVK-7 ERVK-21 ERVK-9 ERVK-24 ERAP1

2.62e-03654436GO:0008233
GeneOntologyMolecularFunctionwide pore channel activity

GJB6 VDAC1

2.88e-0337432GO:0022829
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-7 DTX2 ERVK-21 ERVK-9 ERVK-24 FN1 MUC2 ERAP1

3.46e-031189438GO:0046914
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A6 SLC8A1 SLC29A1 SLC26A5

3.71e-03296434GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC12A6 SLC8A1 SLC29A1 SLC26A5

3.93e-03301434GO:0022853
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC12A6 VDAC1 SLC26A5

4.19e-03151433GO:0008509
GeneOntologyMolecularFunctionchannel activity

SLC12A6 P2RX3 GJB6 TRPC3 VDAC1

5.21e-03525435GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC12A6 P2RX3 GJB6 TRPC3 VDAC1

5.25e-03526435GO:0022803
GeneOntologyMolecularFunctionproteoglycan binding

LRP1 FN1

5.40e-0351432GO:0043394
GeneOntologyBiologicalProcessregulation of cell size

LRP1 SLC12A6 CLASP2 CCR5 FN1 DSCAM SLC26A5

3.86e-07225437GO:0008361
GeneOntologyBiologicalProcessregulation of axon extension

LRP1 CLASP2 CCR5 FN1 DSCAM

2.45e-06104435GO:0030516
GeneOntologyBiologicalProcessregulation of extent of cell growth

LRP1 CLASP2 CCR5 FN1 DSCAM

5.36e-06122435GO:0061387
GeneOntologyBiologicalProcessaxon extension

LRP1 CLASP2 CCR5 FN1 DSCAM

8.79e-06135435GO:0048675
GeneOntologyBiologicalProcessregulation of cellular component size

LRP1 SLC12A6 CLASP2 CCR5 FN1 DSCAM SLC26A5

2.59e-05426437GO:0032535
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

LRP1 CLASP2 CCR5 PPP2R3A FN1 DSCAM

3.43e-05299436GO:0060560
GeneOntologyBiologicalProcessregulation of anatomical structure size

LRP1 SLC12A6 CLASP2 CCR5 SLC8A1 FN1 DSCAM SLC26A5

3.56e-05618438GO:0090066
GeneOntologyBiologicalProcessregulation of locomotion

LRP1 PRKD2 CLASP2 CCR5 SLC8A1 PPP2R3A FN1 DSCAM MUC2 MAPK8IP3 SLC26A5

6.36e-0513274311GO:0040012
GeneOntologyBiologicalProcessneuron projection extension

LRP1 CLASP2 CCR5 FN1 DSCAM

6.85e-05207435GO:1990138
GeneOntologyBiologicalProcessresponse to ATP

SLC8A1 P2RX3 TRPC3

7.90e-0540433GO:0033198
GeneOntologyBiologicalProcessregulation of calcium ion transmembrane transport

VMP1 SLC8A1 P2RX3 TRPC3 VDAC1

8.74e-05218435GO:1903169
GeneOntologyBiologicalProcesscalcium ion transport into cytosol

SLC8A1 P2RX3 TRPC3

9.15e-0542433GO:0060402
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

LRP1 CCR5 SLC8A1 P2RX3 TRPC3

9.94e-05224435GO:0007204
GeneOntologyBiologicalProcesspositive regulation of locomotion

LRP1 PRKD2 CLASP2 SLC8A1 FN1 DSCAM MAPK8IP3 SLC26A5

1.28e-04742438GO:0040017
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

VMP1 CCR5 SLC8A1 P2RX3 TRPC3 VDAC1

1.53e-04392436GO:0070588
GeneOntologyBiologicalProcesscell junction assembly

LRP1 VMP1 CLASP2 FN1 DSCAM GJB6 UBE3B

1.59e-04569437GO:0034329
GeneOntologyBiologicalProcesspositive regulation of axon extension

LRP1 FN1 DSCAM

2.05e-0455433GO:0045773
GeneOntologyBiologicalProcessregulation of monoatomic ion transmembrane transport

VMP1 SLC8A1 P2RX3 TRPC3 VDAC1 SLC26A5

2.13e-04417436GO:0034765
GeneOntologyBiologicalProcessregulation of cell motility

LRP1 PRKD2 CLASP2 CCR5 SLC8A1 PPP2R3A FN1 MUC2 MAPK8IP3 SLC26A5

2.38e-0412804310GO:2000145
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

LRP1 OMA1 PRKD2 CLASP2 CCR5 FN1 DSCAM ERAP1 SLC26A5

3.44e-041090439GO:0022603
GeneOntologyBiologicalProcessresponse to carbohydrate

LRP1 SLC12A6 P2RX3 SLC29A1 GJB6

3.91e-04301435GO:0009743
GeneOntologyBiologicalProcessdevelopmental cell growth

LRP1 CLASP2 CCR5 FN1 DSCAM

3.91e-04301435GO:0048588
GeneOntologyBiologicalProcessplatelet-derived growth factor receptor-beta signaling pathway

LRP1 CLASP2

4.38e-0415432GO:0035791
GeneOntologyBiologicalProcessregulation of calcium ion transport

VMP1 SLC8A1 P2RX3 TRPC3 VDAC1

5.40e-04323435GO:0051924
GeneOntologyBiologicalProcessnegative regulation of cell-substrate junction organization

LRP1 CLASP2

5.66e-0417432GO:0150118
GeneOntologyBiologicalProcessnegative regulation of focal adhesion assembly

LRP1 CLASP2

5.66e-0417432GO:0051895
GeneOntologyBiologicalProcesscalcium ion transport

VMP1 CCR5 SLC8A1 P2RX3 TRPC3 VDAC1

6.16e-04509436GO:0006816
GeneOntologyBiologicalProcessregulation of axonogenesis

LRP1 CCR5 FN1 DSCAM

6.76e-04192434GO:0050770
GeneOntologyBiologicalProcesspositive regulation of cell motility

LRP1 PRKD2 CLASP2 SLC8A1 FN1 MAPK8IP3 SLC26A5

6.88e-04725437GO:2000147
GeneOntologyBiologicalProcesscellular response to glucose stimulus

LRP1 SLC12A6 SLC29A1 GJB6

7.30e-04196434GO:0071333
GeneOntologyBiologicalProcessregulation of cell migration

LRP1 PRKD2 CLASP2 CCR5 SLC8A1 PPP2R3A FN1 MUC2 MAPK8IP3

7.40e-041211439GO:0030334
GeneOntologyBiologicalProcesscellular response to hexose stimulus

LRP1 SLC12A6 SLC29A1 GJB6

7.73e-04199434GO:0071331
GeneOntologyBiologicalProcesscell junction organization

LRP1 VMP1 CLASP2 LRFN2 FN1 DSCAM GJB6 UBE3B

7.98e-04974438GO:0034330
GeneOntologyBiologicalProcesscellular response to monosaccharide stimulus

LRP1 SLC12A6 SLC29A1 GJB6

8.02e-04201434GO:0071326
GeneOntologyBiologicalProcesspositive regulation of calcium ion transport into cytosol

P2RX3 TRPC3

8.69e-0421432GO:0010524
GeneOntologyBiologicalProcesscellular response to carbohydrate stimulus

LRP1 SLC12A6 SLC29A1 GJB6

1.03e-03215434GO:0071322
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

VMP1 SLC12A6 CCR5 SLC8A1 P2RX3 TRPC3 VDAC1 SLC26A5

1.06e-031017438GO:0098660
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CCR5 SLC8A1 P2RX3 TRPC3

1.07e-03217434GO:0097553
GeneOntologyBiologicalProcessaxonogenesis

LRP1 CLASP2 CCR5 FN1 DSCAM MAPK8IP3

1.07e-03566436GO:0007409
GeneOntologyBiologicalProcessintracellular glucose homeostasis

LRP1 SLC12A6 SLC29A1 GJB6

1.08e-03218434GO:0001678
GeneOntologyBiologicalProcessregulation of monoatomic cation transmembrane transport

VMP1 SLC8A1 P2RX3 TRPC3 VDAC1

1.12e-03380435GO:1904062
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

VMP1 SLC8A1 P2RX3 TRPC3 VDAC1 SLC26A5

1.18e-03577436GO:0043269
GeneOntologyBiologicalProcessregulation of extracellular matrix disassembly

LRP1 CLASP2

1.24e-0325432GO:0010715
GeneOntologyBiologicalProcessnegative regulation of cytosolic calcium ion concentration

LRP1 SLC8A1

1.24e-0325432GO:0051481
GeneOntologyBiologicalProcessregulation of transmembrane transport

VMP1 SLC8A1 P2RX3 TRPC3 VDAC1 SLC26A5

1.31e-03589436GO:0034762
GeneOntologyCellularComponentbasal part of cell

LRP1 SLC12A6 CLASP2 SLC8A1 SLC29A1 SLC26A5

1.02e-04378426GO:0045178
GeneOntologyCellularComponentdistal axon

LRP1 CLASP2 SLC8A1 P2RX3 DSCAM MAPK8IP3

2.18e-04435426GO:0150034
GeneOntologyCellularComponentaxon

LRP1 SLC12A6 CLASP2 SLC8A1 P2RX3 DSCAM MAPK8IP3 FBXW11

3.43e-04891428GO:0030424
GeneOntologyCellularComponentbasolateral plasma membrane

LRP1 SLC12A6 SLC8A1 SLC29A1 SLC26A5

4.36e-04320425GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

LRP1 SLC12A6 SLC8A1 SLC29A1 SLC26A5

6.88e-04354425GO:0009925
GeneOntologyCellularComponentpostsynapse

LRP1 SLC8A1 SUSD4 LRFN2 P2RX3 SLC29A1 UBE3B VDAC1

8.29e-041018428GO:0098794
GeneOntologyCellularComponentsynaptic membrane

LRP1 SLC8A1 SUSD4 LRFN2 P2RX3 VDAC1

1.02e-03583426GO:0097060
GeneOntologyCellularComponentpostsynaptic membrane

LRP1 SLC8A1 SUSD4 LRFN2 VDAC1

1.26e-03405425GO:0045211
GeneOntologyCellularComponentgrowth cone

LRP1 CLASP2 DSCAM MAPK8IP3

1.45e-03245424GO:0030426
GeneOntologyCellularComponentsite of polarized growth

LRP1 CLASP2 DSCAM MAPK8IP3

1.63e-03253424GO:0030427
GeneOntologyCellularComponentaxonal growth cone

LRP1 CLASP2

3.69e-0345422GO:0044295
GeneOntologyCellularComponentneuron to neuron synapse

LRP1 SLC8A1 LRFN2 P2RX3 VDAC1

3.81e-03523425GO:0098984
GeneOntologyCellularComponentpostsynaptic density membrane

LRP1 LRFN2 VDAC1

3.85e-03157423GO:0098839
MousePhenoabnormal ear morphology

TPO SLC12A6 FREM2 MUC5B LRBA DSCAM GJB6 SLC26A5

1.29e-05470348MP:0002102
MousePhenoabnormal liver perisinusoidal space morphology

LRP1 CCR5

5.72e-055342MP:0008988
MousePhenoabnormal hippocampus morphology

SLC12A6 SUSD4 LRFN2 DSCAM UBE3B MAPK8IP3

1.29e-04331346MP:0000807
MousePhenoabnormal temporal lobe morphology

SLC12A6 SUSD4 LRFN2 DSCAM UBE3B MAPK8IP3

1.43e-04337346MP:0000801
MousePhenomuscle hypertonia

SLC12A6 DSCAM

2.05e-049342MP:0004143
MousePhenohearing/vestibular/ear phenotype

TPO SLC12A6 FREM2 MUC5B LRBA DSCAM GJB6 UBE3B SLC26A5

2.31e-04905349MP:0005377
MousePhenoabnormal corpus callosum morphology

SLC12A6 DSCAM UBE3B MAPK8IP3

2.59e-04129344MP:0000780
MousePhenoabnormal limbic system morphology

SLC12A6 SUSD4 LRFN2 DSCAM UBE3B MAPK8IP3

2.66e-04378346MP:0004166
MousePhenoabnormal dorsal telencephalic commissure morphology

SLC12A6 DSCAM UBE3B MAPK8IP3

2.83e-04132344MP:0008219
MousePhenoorgan of Corti degeneration

SLC12A6 GJB6 SLC26A5

2.83e-0453343MP:0000043
MousePhenocochlear inner hair cell degeneration

SLC12A6 GJB6 SLC26A5

3.52e-0457343MP:0004398
DomainWxxW_domain

MUC5B MUC2

6.34e-056392IPR025155
DomainMucin2_WxxW

MUC5B MUC2

6.34e-056392PF13330
DomainCalx_beta

FREM2 SLC8A1

1.18e-048392SM00237
DomainCalx_beta

FREM2 SLC8A1

1.52e-049392IPR003644
DomainCalx-beta

FREM2 SLC8A1

1.52e-049392PF03160
DomainSushi

TPO SUSD4 SUSD1

1.73e-0452393PF00084
DomainCCP

TPO SUSD4 SUSD1

1.94e-0454393SM00032
DomainSUSHI

TPO SUSD4 SUSD1

2.16e-0456393PS50923
DomainSushi_SCR_CCP_dom

TPO SUSD4 SUSD1

2.28e-0457393IPR000436
DomainTIL

MUC5B MUC2

2.77e-0412392PF01826
DomainC8

MUC5B MUC2

2.77e-0412392PF08742
DomainUnchr_dom_Cys-rich

MUC5B MUC2

3.27e-0413392IPR014853
DomainC8

MUC5B MUC2

3.27e-0413392SM00832
DomainTIL_dom

MUC5B MUC2

3.81e-0414392IPR002919
DomainVWFD

MUC5B MUC2

5.01e-0416392PS51233
DomainVWD

MUC5B MUC2

5.01e-0416392SM00216
DomainVWF_type-D

MUC5B MUC2

5.01e-0416392IPR001846
DomainVWD

MUC5B MUC2

5.01e-0416392PF00094
DomainCTCK_1

MUC5B MUC2

6.36e-0418392PS01185
DomainVWC_out

MUC5B MUC2

7.10e-0419392SM00215
DomainEGF_CA

LRP1 TPO SUSD1

7.64e-0486393PF07645
DomainCT

MUC5B MUC2

9.56e-0422392SM00041
DomainEGF_Ca-bd_CS

LRP1 TPO SUSD1

1.08e-0397393IPR018097
DomainEGF_CA

LRP1 TPO SUSD1

1.15e-0399393PS01187
DomainASX_HYDROXYL

LRP1 TPO SUSD1

1.18e-03100393PS00010
DomainCys_knot_C

MUC5B MUC2

1.24e-0325392IPR006207
DomainCTCK_2

MUC5B MUC2

1.24e-0325392PS01225
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 TPO SUSD1

1.40e-03106393IPR000152
DomainEGF_1

LRP1 TPO FN1 SUSD1

1.92e-03255394PS00022
DomainEGF-like_CS

LRP1 TPO FN1 SUSD1

2.09e-03261394IPR013032
DomainEGF_CA

LRP1 TPO SUSD1

2.09e-03122393SM00179
DomainEGF-like_Ca-bd_dom

LRP1 TPO SUSD1

2.19e-03124393IPR001881
DomainVWFC_1

MUC5B MUC2

2.56e-0336392PS01208
DomainVWC

MUC5B MUC2

2.85e-0338392SM00214
DomainVWFC_2

MUC5B MUC2

2.85e-0338392PS50184
DomainWD40_repeat_dom

LRBA MAPK8IP3 FBXW11 WDR48

3.33e-03297394IPR017986
DomainVWF_dom

MUC5B MUC2

3.47e-0342392IPR001007
Domainfn3

LRFN2 FN1 DSCAM

4.66e-03162393PF00041
Domain-

LRBA MAPK8IP3 FBXW11 WDR48

4.99e-033333942.130.10.10
DomainWD40/YVTN_repeat-like_dom

LRBA MAPK8IP3 FBXW11 WDR48

5.10e-03335394IPR015943
DomainFN3

LRFN2 FN1 DSCAM

6.73e-03185393SM00060
DomainFN3

LRFN2 FN1 DSCAM

8.21e-03199393PS50853
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

SLC8A1 P2RX3 TRPC3

2.99e-0527323MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

SLC8A1 P2RX3 TRPC3

3.35e-0528323M924
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-24

1.42e-061843318664271
Pubmed

TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.

SLC8A1 TRPC3

1.49e-06243225631581
Pubmed

Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger.

SLC8A1 TRPC3

1.49e-06243214736881
Pubmed

The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.

LRP1 FN1

1.49e-06243211867643
Pubmed

LRP1 is required for novobiocin-mediated fibronectin turnover.

LRP1 FN1

1.49e-06243230061663
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

1.49e-06243220873538
Pubmed

A new mutation in the human pres gene and its effect on prestin function.

GJB6 SLC26A5

4.48e-06343217786286
Pubmed

Acetylcholine attenuated TNF-α-induced intracellular Ca2+ overload by inhibiting the formation of the NCX1-TRPC3-IP3R1 complex in human umbilical vein endothelial cells.

SLC8A1 TRPC3

4.48e-06343228395930
Pubmed

MUC5B mucin production is upregulated by fibronectin and laminin in human lung epithelial cells via the integrin and ERK dependent pathway.

MUC5B FN1

4.48e-06343226057585
Pubmed

Coupling between the TRPC3 ion channel and the NCX1 transporter contributed to VEGF-induced ERK1/2 activation and angiogenesis in human primary endothelial cells.

SLC8A1 TRPC3

4.48e-06343228535874
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2

4.48e-06343219718741
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-7 ERVK-21 ERVK-9 ERVK-24

5.70e-069443421542922
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC2

8.94e-06443225638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC2

8.94e-06443217471237
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC2

8.94e-06443222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC2

8.94e-06443214984930
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-7 ERVK-24

8.94e-06443210469592
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC2

8.94e-06443229869461
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC5B MUC2

8.94e-06443221596555
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC2

8.94e-06443223807779
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC2

8.94e-06443212676567
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC2

1.49e-05543211062147
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-7 ERVK-21

1.49e-05543212629516
Pubmed

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

MUC5B MUC2

1.49e-05543224840470
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC2

1.49e-05543216188033
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC5B MUC2

2.23e-05643219110483
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

VMP1 SLC12A6 LRBA SLC29A1 COG4 FBXW11

3.48e-0550443634432599
Pubmed

Splice variant IVS2-2A>G in the SLC26A5 (Prestin) gene in five Estonian families with hearing loss.

GJB6 SLC26A5

4.16e-05843219027966
Pubmed

Genetic analysis of presbycusis by arrayed primer extension.

GJB6 SLC26A5

4.16e-05843218988928
Pubmed

Genotyping with a 198 mutation arrayed primer extension array for hereditary hearing loss: assessment of its diagnostic value for medical practice.

GJB6 SLC26A5

4.16e-05843220668687
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-21 ERVK-9

9.78e-051243214557543
Pubmed

Deletion of astroglial connexins weakens the blood-brain barrier.

FN1 GJB6

1.35e-041443222472609
Pubmed

A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN).

LRP1 TPO CCR5

1.35e-048043319420105
Pubmed

Sprouty1 haploinsufficiency prevents renal agenesis in a model of Fraser syndrome.

FREM2 FN1

1.55e-041543223064016
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

LRP1 PRKD2 LRBA FN1 DSCAM COG4 MAPK8IP3 FBXW11

1.56e-04128543835914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CLASP2 MAPK8IP3 FBXW11

1.74e-048743312465718
Pubmed

Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum.

MUC2 VDAC1

1.77e-041643227019864
Pubmed

Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors.

P2RX3 TRPC3

2.01e-041743225834056
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC5B MUC2

2.26e-041843218834073
Pubmed

Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism.

MUC2 VDAC1

2.80e-042043236189989
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

LRP1 SLC29A1 GJB6

3.02e-0410543330280653
Pubmed

Identification of cellular proteins required for replication of human immunodeficiency virus type 1.

VMP1 CCR5

3.09e-042143222404213
Pubmed

The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation.

VMP1 VDAC1

3.40e-042243228890335
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

FREM2 FN1

3.72e-042343218787044
Pubmed

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

P2RX3 TRPC3

3.72e-042343216446141
Pubmed

A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.

P2RX3 TRPC3

4.05e-042443217553423
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

LRP1 SLC12A6 CLASP2 PPP2R3A LRFN2 LRBA MAPK8IP3 FBXW11

4.21e-04148943828611215
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

FREM2 FN1

5.93e-042943222613833
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

FREM2 SLC8A1 FN1

7.00e-0414043326930384
Pubmed

Direction selectivity in the retina is established independent of visual experience and cholinergic retinal waves.

P2RX3 TRPC3

8.66e-043543218498732
Pubmed

Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons.

P2RX3 TRPC3

9.67e-043743218498735
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

SLC8A1 TRPC3

1.02e-033843230786075
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

VMP1 SLC12A6 LRBA SLC29A1 VDAC1 EBP

1.06e-0395243638569033
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

LRP1 MUC5B ERAP1

1.11e-0316443332409323
Pubmed

Novel Cul3 binding proteins function to remodel E3 ligase complexes.

LRFN2 WDR48

1.13e-034043225011449
Pubmed

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.

RNF152 FBXW11

1.13e-034043230759391
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

FREM2 FN1 MUC2

1.17e-0316743322159717
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5B MUC2

1.19e-034143222675208
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

GON4L FREM2 COG4 UBE3B WDR48

1.20e-0365043538777146
Cytoband1q22

GON4L ERVK-7

1.32e-03574321q22
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

TPO SUSD4 SUSD1

1.14e-04573031179
GeneFamilySolute carriers

SLC12A6 SLC25A53 SLC8A1 SLC29A1 SLC26A5

4.41e-04395305752
GeneFamilyCD molecules|Mucins

MUC5B MUC2

5.48e-0421302648
GeneFamilyFibronectin type III domain containing

LRFN2 FN1 DSCAM

2.32e-03160303555
GeneFamilyWD repeat domain containing

LRBA FBXW11 WDR48

9.15e-03262303362
GeneFamilyActins|Deafness associated genes

GJB6 SLC26A5

1.50e-021133021152
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRFN2 DSCAM

2.91e-02161302593
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 LRFN2 P2RX3 DSCAM

8.91e-0615039447ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLC8A1 FN1 MUC2 TRPC3

9.89e-06154394e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SUSD4 FN1 SLC29A1 GJB6

2.26e-05190394b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 PPP2R3A SUSD4 LRBA

2.45e-0519439493c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A SUSD4 LRBA SUSD1

2.55e-05196394c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B SUSD4 DTX2 RNF152

2.65e-051983941fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B SUSD4 DTX2 RNF152

2.65e-05198394af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellIIH-CD4-CD8_2|IIH / Condition, Cell_class and T cell subcluster

PPP2R3A GJB6 SLC26A5

2.33e-041373935614a086f5f698e0965f3c7699cffefec5c3b87e
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B SUSD4 DTX2

3.16e-041523931b2a39ae159e79f1fb18d6d164bd7acab5299fca
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|390C / Donor, Lineage, Cell class and subclass (all cells)

CCR5 LRBA GJB6

3.28e-04154393a90c4c45685eae8d21d03479cfd5a23f6ed3ca07
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-3|TCGA-Pancreas / Sample_Type by Project: Shred V9

VDAC1 EBP SLC26A5

3.54e-04158393ec1a71b8f46179642b5af20e27764bb43c4b8e99
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B SUSD4 DTX2

3.74e-041613932d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellfacs-Marrow-T_cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

3.88e-0416339330cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCellfacs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

3.88e-04163393ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 FREM2 MUC5B

3.95e-04164393b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 FREM2 MUC5B

3.95e-04164393c5b2001280a43da855017361a3f6071a0e492848
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 FREM2 MUC5B

4.02e-041653931a114eacaab598f755a173a3fed842ba91f689dd
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 FREM2 MUC5B

4.02e-041653939cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.09e-04166393e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.09e-041663933ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.09e-04166393f751cbd01d4978ded7755874ab60504f6291afd7
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

MUC5B SUSD4 DTX2

4.16e-041673936efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.38e-04170393a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.38e-04170393ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OMA1 SLC8A1 DSCAM

4.53e-04172393356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.53e-041723935f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OMA1 SLC8A1 DSCAM

4.53e-0417239346fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OMA1 SLC8A1 DSCAM

4.53e-04172393438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

SUSD4 FN1 TRPC3

4.53e-04172393644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

DUSP19 RNF152 TRPC3

4.53e-04172393858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF152 DSCAM SUSD1

4.61e-041733930bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 SLC8A1 FN1

4.69e-04174393d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.77e-0417539369b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCelldroplet-Liver-Npc-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 CCR5 SLC8A1

4.77e-041753931973fff0d7e1a94b31f461a39b91cc7984ebd8f1
ToppCelldroplet-Liver-Npc-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 CCR5 SLC8A1

4.77e-0417539392a4a3fd323ee8360edd659f9e16dfddc8788e2f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 FN1

4.77e-041753934f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(INS+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRFN2 SLC29A1 SLC26A5

4.85e-041763936b04672f295d7680ba00714a72785314a619c893
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Macrophage|GI_small-bowel / Manually curated celltypes from each tissue

LRP1 SLC8A1 FN1

4.85e-041763934be270f6bb7da4070f972aca403109751646d155
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC8A1 RNF152

4.85e-041763937622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCellB_cell_maturation-CD34+_pre-plamsa|World / Lineage and Cell class

LRFN2 RNF152 VDAC1

4.93e-041773933ff06100deee9bee852a52078666999a9f7beaf1
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho|lymph-node_spleen / Manually curated celltypes from each tissue

LRP1 PPP2R3A SLC29A1

4.93e-0417739353040dbeb18574a48e352e4bce252c7c3018762c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCR5 SUSD4 DUSP19

5.01e-041783930290868dc990878eac5c182fe64968333bc52450
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

LRP1 SLC8A1 DSCAM

5.18e-041803937be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A SUSD4 LRBA

5.18e-041803939e09b3dfe344b5d50520711513d389865d73a861
ToppCellControl-Myeloid-Alveolar_macrophages|Control / group, cell type (main and fine annotations)

LRP1 SLC8A1 FN1

5.26e-041813938d2102c8c86c59a82610f26f90946b290552e666
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B SUSD4 DTX2

5.35e-041823933f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SUSD4 LRBA

5.35e-041823935f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellControl-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

MUC5B SUSD4 RNF152

5.43e-04183393bdd461349a1ef43a015843937d26e8d3571ecc22
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

MUC5B SUSD4 DTX2

5.43e-04183393940cbe298e9c53b5622af09264586ed823d3141f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 SLC8A1 MUC5B

5.52e-04184393ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 SLC8A1 MUC5B

5.52e-041843932cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 SLC8A1 MUC5B

5.52e-041843932b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 RNF152 TRPC3

5.61e-041853933a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

FREM2 SUSD4 RNF152

5.61e-04185393c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUSD4 RNF152 TRPC3

5.61e-04185393224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A SUSD4 LRBA

5.69e-041863931850583d23903d08226aeb0edb3e07b0994330e4
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FN1 SLC29A1

5.69e-04186393a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A SUSD4 LRBA

5.69e-041863934dafc215c42e7949f932a3627359c107943b5d6b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 PPP2R3A SUSD1

5.69e-0418639308632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRP1 FN1 VDAC1

5.69e-0418639338f9f7d3b782978fd23b2a7fe565266285d39e44
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCR5 SLC8A1 FN1

5.78e-0418739372e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

FREM2 PPP2R3A SUSD4

5.87e-041883931d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRP1 FN1 VDAC1

5.87e-04188393e35104ca327c2d9eb6ffed658051f62f855a0a0e
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CLASP2 SLC8A1 FN1

5.87e-0418839334e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LRP1 FN1 ERAP1

5.97e-04189393c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FN1 SLC29A1

5.97e-04189393dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 RNF152 TRPC3

6.06e-04190393a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC8A1 LRFN2 DSCAM

6.06e-04190393d594da827e3c16644952b9589cc12b947ce36279
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SUSD4 DSCAM

6.06e-041903939b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellClub|World / shred by cell class for parenchyma

MUC5B SUSD4 DTX2

6.06e-041903931974d559d7fee6cb68065b18af8bd38b64910622
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC8A1 LRFN2 DSCAM

6.06e-0419039349e09cdb843b3d889a06a811aa5affae68b25a75
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 RNF152 TRPC3

6.06e-0419039357c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SUSD4 RNF152 TRPC3

6.06e-04190393f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SUSD4 DSCAM

6.06e-04190393d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LRP1 FN1 VDAC1

6.15e-041913935c0c44612b4cdbf89c0f1f219416374a7541f610
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRFN2 RNF152 TRPC3

6.15e-041913936e7f589efc997f32175e0789c5ea7ca46e1389b8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SUSD4 DSCAM

6.15e-04191393ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SUSD4 DSCAM

6.15e-04191393478e8341ee03b05501e2233e02cef5f97492c95d
ToppCelldroplet-Trachea-nan-3m-Epithelial-neuroendocrine_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRFN2 RNF152 TRPC3

6.15e-041913933ce403e0beedb544edeb3ae6eb30267040d00c21
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRFN2 RNF152 TRPC3

6.15e-0419139372f1ddc09080dbfea8d51294cbf7f9d4925f9cc0
ToppCellSevere-Myeloid-Macrophages-FABP4+|Severe / Condition, Lineage, Cell class and cell subclass

FN1 SUSD1 SLC29A1

6.24e-0419239330aad927ad40d8abaf9d0539bf8cb9d88d16f24d
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

FREM2 SLC8A1 PPP2R3A

6.24e-04192393760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FN1 SLC29A1

6.24e-041923932d9e2262f1342fe17735f21f733c029d1275e955
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FN1 SLC29A1

6.24e-04192393beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellFibroblasts-CD55+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SUSD4 SLC29A1 GJB6

6.34e-041933938f4bf9a2fbedae35432dad96730b00c70185874c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLASP2 CCR5 SLC8A1

6.34e-0419339306b65110db974f4ef90d3511ff34428976a52c9c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A RNF152 LRBA

6.34e-041933933866667dd221612589ae50f5c52f73a183a49ce6
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLASP2 CCR5 SLC8A1

6.34e-041933939c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLASP2 CCR5 SLC8A1

6.34e-04193393a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FN1 SLC29A1

6.34e-04193393160691b671710be10220803d788c2c961c236af1
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLASP2 CCR5 SLC8A1

6.34e-04193393b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B SUSD4 DTX2

6.43e-04194393e0228f593c3493175962a4817500d4337ddc4e88
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCR5 SLC8A1 FN1

6.43e-04194393e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B SUSD4 DTX2

6.53e-04195393e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 FN1 SUSD1

6.53e-041953939e49e59a20b1bbd6167d594c33ab6bdfe2c1ebaf
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 FN1 SUSD1

6.53e-04195393412a9fcf9f075d97fae254bbd89774e4b1face07
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF152 FN1 SLC29A1

6.63e-04196393cb5860f580b477bfa52b22cdc21b808e1371e6e0
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF152 FN1 SLC29A1

6.63e-04196393cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCellVE-granulo1-|VE / Condition, Cell_class and T cell subcluster

LRP1 SLC8A1 FN1

6.63e-04196393ab3f2ce294c7e503d86254a195be0cf500a2c5e4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 PPP2R3A LRBA

6.63e-041963936ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
DrugEthotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A

LRP1 MUC5B FN1 MUC2 MAPK8IP3

1.99e-051953956052_UP
DrugStrophanthidin [66-28-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A

PPP2R3A DSCAM SLC29A1 UBE3B MAPK8IP3

2.04e-051963957182_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

GON4L PPP2R3A SLC29A1 UBE3B WDR48

2.09e-051973956222_UP
DrugLysergol [602-85-7]; Down 200; 15.8uM; PC3; HT_HG-U133A

LRP1 CLASP2 ERAP1 SLC29A1 MAPK8IP3

2.09e-051973956621_DN
Drug16, 16-dimethylprostaglandin E2 methyl acetate solution; Up 200; 10uM; MCF7; HT_HG-U133A

MUC5B PPP2R3A SLC29A1 FBXW11 WDR48

2.14e-051983956597_UP
DrugMeptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; PC3; HT_HG-U133A

LRP1 FN1 DSCAM ERAP1 TRPC3

2.19e-051993954188_UP
Diseasecoronary artery disease

LRP1 OMA1 PRKD2 PPP2R3A LRFN2 FN1 DSCAM UBE3B MAPK8IP3

1.59e-051194389EFO_0001645
Diseasestatus epilepticus (biomarker_via_orthology)

CCR5 SLC8A1 GJB6

2.92e-04100383DOID:1824 (biomarker_via_orthology)
DiseasePolydactyly

FREM2 UBE3B EBP

4.63e-04117383C0152427
Diseaseanterior uveitis

CNBD1 ERAP1

7.82e-0432382EFO_1000811
Diseasebrain ischemia (implicated_via_orthology)

SLC8A1 SLC29A1

9.35e-0435382DOID:2316 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

LRFN2 LRBA DSCAM

9.91e-04152383DOID:0060041 (implicated_via_orthology)
Diseasesleep duration

OMA1 CNBD1 SLC8A1 PPP2R3A

1.18e-03362384EFO_0005271
DiseaseNodular glomerulosclerosis

FN1 VDAC1

1.28e-0341382C0017667

Protein segments in the cluster

PeptideGeneStartEntry
TTKVTGSLETKYRWT

VDAC1

51

P21796
VTWVKTIGSTTIINL

ERVK-9

626

Q9UKH3
TTVTTWTIRDKFARL

COG4

716

Q9H9E3
TVTFGVVTSVITWVV

CCR5

141

P51681
TATEKTTLWVTPSIR

MUC5B

1461

Q9HC84
SRVWILTSTLTTSKV

MAPK8IP3

771

Q9UPT6
WKRRLIFTVGTSSTT

DTX2

556

Q86UW9
DGSSRSVIVDTKITW

LRP1

3176

Q07954
WRTGTDLSKSSSVTV

FREM2

2031

Q5SZK8
LTTLTFWGTTKVEIT

ERAP1

71

Q9NZ08
ESSTGIIVIWDKRTT

MUC2

961

Q02817
TSTVICRWTRTGTKS

TPO

866

P07202
IVSASGDRTIKVWST

FBXW11

376

Q9UKB1
TTRKSSTTLREGWVV

PRKD2

391

Q9BZL6
VWVDTLSITHSKVTF

LRBA

911

P50851
TVNRSWSGKITSTEI

PPP2R3A

856

Q06190
VTWVKTIGSTTIINL

ERVK-24

516

P61566
VTWVKTIGSTTIINL

ERVK-7

516

P61567
ATETTITISWRTKTE

FN1

1916

P02751
ITISWRTKTETITGF

FN1

1921

P02751
HSTSIGKVWITVIFI

GJB6

16

O95452
VSSTGEKVVLWTREA

GON4L

2146

Q3T8J9
VTWVKTIGSTTIINL

ERVK-21

626

P61565
TVTWVKTIGSTTIIN

HERVK_113

626

Q902F9
FSVTGVLVVTTWLLS

EBP

36

Q15125
RAWKTFIGTVRVTTA

SLC12A6

871

Q9UHW9
ETTKSVVVKSWTIGI

P2RX3

11

P56373
TVVSWEKDTVSLVSG

DSCAM

156

O60469
VKSSTWSGVCTVILV

RNF152

161

Q8N8N0
KIELTIWLTTFVSSL

SLC26A5

466

P58743
VILRSSVTWGLTTAI

SLC25A53

276

Q5H9E4
GLSSTKSKEIWRITS

OMA1

81

Q96E52
TVEVKSSIAGSSTWE

SLC29A1

311

Q99808
TVFSETWLKGSTVVA

CNBD1

181

Q8NA66
AVSRVITWTTEPKSS

CLASP2

821

O75122
TIIVSGSTEKVLRVW

WDR48

181

Q8TAF3
WTTTIIISSSLKSYE

SPO16

11

Q5VVC0
TWRESTLTCTEILTK

SUSD1

286

Q6UWL2
LLTTWKIVAFTATSV

SUSD4

316

Q5VX71
LVTFTDTSTWKILRG

UBE3B

166

Q7Z3V4
QSSVVGSSVVTWKIS

nan

31

Q6ZVU0
WSIFGLSEVTSVVLK

TRPC3

611

Q13507
GTISLWSIISKVRIE

VMP1

176

Q96GC9
TRVTTLTGKKIIETW

DUSP19

21

Q8WTR2
EKTSITTWTIFSIIS

GARIN5B

271

Q8N5Q1
VLVSEVTTTSALVKW

LRFN2

426

Q9ULH4
ETTKTTVRIWNETVS

SLC8A1

121

P32418