Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	chromatin binding	ASXL1 RAN DDX12P HDAC4 TOX ZNF683 ISL1 MORC2 GRHL2 CREB3L1 PHC2 CITED2 TOX3 KMT2A TAL1 L3MBTL3 SMAD4 HR	5.25e-06	739	142	18	GO:0003682
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	ASXL1 HDAC4 NFKBID BBS1 ISL1 CITED2 MED4 MYOCD TAL1 EPAS1 SMAD4 HR	4.44e-05	417	142	12	GO:0061629
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	ASXL1 HDAC4 NFKBID BBS1 ISL1 GRHL2 CITED2 MED4 KMT2A MYOCD TAL1 EPAS1 SMAD4 HR	7.14e-05	582	142	14	GO:0140297
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRD PTPRF PTPRN2	2.23e-04	17	142	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRD PTPRF PTPRN2	2.23e-04	17	142	3	GO:0019198
GeneOntologyMolecularFunction	transcription factor binding	ASXL1 HDAC4 PCLO NFKBID BBS1 ISL1 GRHL2 CITED2 MED4 KMT2A MYOCD TAL1 EPAS1 SMAD4 HR	3.10e-04	753	142	15	GO:0008134
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2D SETBP1 KMT2A	3.67e-04	20	142	3	GO:0042800
GeneOntologyMolecularFunction	transcription coregulator activity	ZXDC ASXL1 HDAC4 CITED2 KMT2D MED4 TOX3 KDM2B MYOCD YY1AP1 MRTFA HR	6.92e-04	562	142	12	GO:0003712
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	ASXL1 IKZF2 HIVEP1 HDAC4 TOX CDK12 IKBKG RFX6 ZNF395 ISL1 MLXIP GRHL2 CREB3L1 CITED2 KMT2D MED4 TOX3 NLRC5 KMT2A PLAGL1 MYOCD TAL1 EPAS1 MRTFA SMAD4	9.86e-06	1390	143	25	GO:0045944
GeneOntologyCellularComponent	nucleotide-activated protein kinase complex	PRKAB1 PRKAB2 SESN2	5.07e-05	11	144	3	GO:0031588
GeneOntologyCellularComponent	nuclear protein-containing complex	ASXL1 RAN MMS22L DDX12P HDAC4 CDK12 MLXIP PHC2 KMT2D MED4 NUP155 NUP210 NPAP1 KDM2B KMT2A ACIN1 MYOCD YY1AP1 SAGE1 SF3B2 SMAD4 HR	1.87e-04	1377	144	22	GO:0140513
Domain	-	ACIN1 MYOCD SF3B2 MRTFA	1.55e-05	21	138	4	1.10.720.30
Domain	SAP	ACIN1 MYOCD SF3B2 MRTFA	1.88e-05	22	138	4	PF02037
Domain	SAP	ACIN1 MYOCD SF3B2 MRTFA	2.27e-05	23	138	4	SM00513
Domain	-	CBLL1 TRIM49 TRIM41 PCLO TRIM49C RNF212 ZFPL1 UBE4A KMT2D KDM2B KMT2A RIMS2 TRIM49B	2.91e-05	449	138	13	3.30.40.10
Domain	SAP	ACIN1 MYOCD SF3B2 MRTFA	3.20e-05	25	138	4	PS50800
Domain	SAP_dom	ACIN1 MYOCD SF3B2 MRTFA	3.20e-05	25	138	4	IPR003034
Domain	Znf_RING/FYVE/PHD	CBLL1 TRIM49 TRIM41 PCLO TRIM49C RNF212 ZFPL1 UBE4A KMT2D KDM2B KMT2A RIMS2 TRIM49B	3.66e-05	459	138	13	IPR013083
Domain	AMPKBI	PRKAB1 PRKAB2	5.42e-05	2	138	2	PF04739
Domain	AMPKBI	PRKAB1 PRKAB2	5.42e-05	2	138	2	SM01010
Domain	AMPK1_CBM	PRKAB1 PRKAB2	5.42e-05	2	138	2	PF16561
Domain	AMPK1_CBM	PRKAB1 PRKAB2	5.42e-05	2	138	2	IPR032640
Domain	ASC_dom	PRKAB1 PRKAB2	5.42e-05	2	138	2	IPR006828
Domain	ZF_BBOX	TRIM49 TRIM41 TRIM49C ZFPL1 TRIM49B	3.16e-04	80	138	5	PS50119
Domain	FYrich_C	KMT2D KMT2A	5.34e-04	5	138	2	IPR003889
Domain	FYrich_N	KMT2D KMT2A	5.34e-04	5	138	2	IPR003888
Domain	FYRC	KMT2D KMT2A	5.34e-04	5	138	2	SM00542
Domain	FYRN	KMT2D KMT2A	5.34e-04	5	138	2	SM00541
Domain	FYRN	KMT2D KMT2A	5.34e-04	5	138	2	PF05964
Domain	FYRC	KMT2D KMT2A	5.34e-04	5	138	2	PF05965
Domain	FYRC	KMT2D KMT2A	5.34e-04	5	138	2	PS51543
Domain	FYRN	KMT2D KMT2A	5.34e-04	5	138	2	PS51542
Domain	RPEL	MYOCD MRTFA	1.11e-03	7	138	2	PS51073
Domain	RPEL	MYOCD MRTFA	1.11e-03	7	138	2	SM00707
Domain	RPEL	MYOCD MRTFA	1.11e-03	7	138	2	PF02755
Domain	RPEL_repeat	MYOCD MRTFA	1.11e-03	7	138	2	IPR004018
Domain	ZF_RING_1	CBLL1 TRIM49 TRIM41 TRIM49C RNF212 ZFPL1 KMT2D TRIM49B	1.46e-03	291	138	8	PS00518
Domain	ZF_RING_2	CBLL1 TRIM49 TRIM41 TRIM49C RNF212 ZFPL1 KMT2D TRIM49B	1.69e-03	298	138	8	PS50089
Domain	BBOX	TRIM49 TRIM41 TRIM49C TRIM49B	1.70e-03	69	138	4	SM00336
Domain	Butyrophylin	TRIM49 TRIM41 TRIM49C TRIM49B	1.79e-03	70	138	4	IPR003879
Domain	-	TRIM49 TRIM41 TRIM49C TRIM49B	1.89e-03	71	138	4	4.10.45.10
Domain	RING	CBLL1 TRIM49 TRIM41 TRIM49C RNF212 ZFPL1 KMT2D TRIM49B	1.96e-03	305	138	8	SM00184
Domain	zf-B_box	TRIM49 TRIM41 TRIM49C TRIM49B	1.99e-03	72	138	4	PF00643
Domain	Tyr_Pase_AS	PTPRD PTPRF SSH1 PTPRN2	2.09e-03	73	138	4	IPR016130
Domain	HMG_BOX_1	TOX TOX3	2.35e-03	10	138	2	PS00353
Domain	PTPc	PTPRD PTPRF PTPRN2	2.36e-03	36	138	3	SM00194
Domain	ZF_CXXC	KDM2B KMT2A	2.85e-03	11	138	2	PS51058
Domain	Znf_CXXC	KDM2B KMT2A	2.85e-03	11	138	2	IPR002857
Domain	zf-CXXC	KDM2B KMT2A	2.85e-03	11	138	2	PF02008
Domain	Znf_RING	CBLL1 TRIM49 TRIM41 TRIM49C RNF212 ZFPL1 KMT2D TRIM49B	2.95e-03	326	138	8	IPR001841
Domain	TYR_PHOSPHATASE_PTP	PTPRD PTPRF PTPRN2	2.97e-03	39	138	3	PS50055
Domain	Znf_B-box	TRIM49 TRIM41 TRIM49C TRIM49B	3.06e-03	81	138	4	IPR000315
Domain	DUF4599	SPATA31A3 SPATA31C1	3.41e-03	12	138	2	PF15371
Domain	DUF4599	SPATA31A3 SPATA31C1	3.41e-03	12	138	2	IPR027970
Domain	PTPase_domain	PTPRD PTPRF PTPRN2	3.43e-03	41	138	3	IPR000242
Domain	Y_phosphatase	PTPRD PTPRF PTPRN2	3.43e-03	41	138	3	PF00102
Domain	TYR_PHOSPHATASE_1	PTPRD PTPRF SSH1 PTPRN2	3.79e-03	86	138	4	PS00383
Domain	TYR_PHOSPHATASE_dom	PTPRD PTPRF SSH1 PTPRN2	3.95e-03	87	138	4	IPR000387
Domain	SPRY	TRIM49 TRIM41 TRIM49C TRIM49B	3.95e-03	87	138	4	SM00449
Domain	TYR_PHOSPHATASE_2	PTPRD PTPRF SSH1 PTPRN2	3.95e-03	87	138	4	PS50056
Domain	Znf_PHD	ASXL1 KMT2D KDM2B KMT2A	4.64e-03	91	138	4	IPR001965
Domain	Znf_FYVE_PHD	PCLO KMT2D KDM2B KMT2A RIMS2	4.73e-03	147	138	5	IPR011011
Domain	-	PTPRD PTPRF SSH1 PTPRN2	4.83e-03	92	138	4	3.90.190.10
Domain	SPRY	TRIM49 TRIM41 TRIM49C TRIM49B	5.21e-03	94	138	4	PF00622
Domain	SPRY_dom	TRIM49 TRIM41 TRIM49C TRIM49B	5.21e-03	94	138	4	IPR003877
Domain	PDZ	PCLO FRMPD1 TIAM1 RIMS2 AHNAK2	5.30e-03	151	138	5	PS50106
Domain	B30.2/SPRY	TRIM49 TRIM41 TRIM49C TRIM49B	5.41e-03	95	138	4	IPR001870
Domain	B302_SPRY	TRIM49 TRIM41 TRIM49C TRIM49B	5.41e-03	95	138	4	PS50188
Domain	ZF_PHD_2	ASXL1 KMT2D KDM2B KMT2A	5.41e-03	95	138	4	PS50016
Domain	PDZ	PCLO FRMPD1 TIAM1 RIMS2 AHNAK2	5.45e-03	152	138	5	IPR001478
Domain	ZF_PHD_1	ASXL1 KMT2D KDM2B KMT2A	5.61e-03	96	138	4	PS01359
Domain	Post-SET_dom	KMT2D KMT2A	6.08e-03	16	138	2	IPR003616
Domain	PostSET	KMT2D KMT2A	6.08e-03	16	138	2	SM00508
Domain	AT_hook	SETBP1 KMT2A	6.08e-03	16	138	2	PF02178
Domain	POST_SET	KMT2D KMT2A	6.08e-03	16	138	2	PS50868
Domain	Prot-tyrosine_phosphatase-like	PTPRD PTPRF SSH1 PTPRN2	6.25e-03	99	138	4	IPR029021
Domain	HMG_box	TOX KMT2D TOX3	7.06e-03	53	138	3	PF00505
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ALX3 IKZF2 HDAC4 IKBKG ISL1 MLXIP CREB3L1 MED4 TOX3 ZSCAN18 KDM2B MYOCD TAL1 L3MBTL3 EPAS1 MRTFA SMAD4 HR	2.98e-08	877	145	18	20211142
Pubmed	Functional proteomics mapping of a human signaling pathway.	TOM1L2 SMG1 HIVEP1 CDK12 CYP11A1 IKBKG LAMA5 KMT2D MED4 NUP155 PTPRF PLAGL1 KIF13A EPAS1 SMAD4	2.98e-08	591	145	15	15231748
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 CDK12 LAMA5 NACAD NUP155 SETBP1 FAM20B KDM2B RACGAP1 CACNA1G RIMS2 ESPL1 L3MBTL3	3.75e-07	529	145	13	14621295
Pubmed	Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells.	PRKAB1 PRKAB2 SESN2	7.05e-07	5	145	3	22363791
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	HIVEP1 CDK12 MORC2 PHC2 OTUD7B EPS15L1 KMT2D SSH1 KDM2B KMT2A ACIN1 YY1AP1 ESPL1 SF3B2 MRTFA	9.31e-07	774	145	15	15302935
Pubmed	An inter-species protein-protein interaction network across vast evolutionary distance.	UBL7 WBP11 IKZF2 TRIM41 DBNDD2 IKBKG ISL1 CCDC57 CREB3L1 PHC2 MED4 PSME3	9.58e-07	483	145	12	27107014
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	CBLL1 IKZF2 RFX6 CCDC57 CREB3L1 MED4 PRKAB2 CACNA1G PSME3 L3MBTL3 MRTFA	1.09e-06	402	145	11	24722188
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZXDC ASXL1 HIVEP1 TROAP HJURP PHC2 KMT2D KDM2B KMT2A SESN2 PSME3 L3MBTL3	1.24e-06	495	145	12	27705803
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZXDC IKZF2 HIVEP1 TOX ZDHHC14 IKBKG GRHL2 ZFPL1 CITED2 TOX3 ACIN1 SF3B2 EPAS1 MRTFA SMAD4	1.58e-06	808	145	15	20412781
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 AARS1 WBP11 SLK CDK12 MORC2 SLC30A5 NUP155 RACGAP1 KMT2A YY1AP1 SF3B2 HR	3.66e-06	650	145	13	38777146
Pubmed	The mutational landscape of lethal castration-resistant prostate cancer.	ASXL1 KMT2D KMT2A	3.91e-06	8	145	3	22722839
Pubmed	A census of human transcription factors: function, expression and evolution.	ALX3 HIVEP1 ZNF395 ISL1 MLXIP GRHL2 CREB3L1 KMT2D SETBP1 TOX3 KMT2A PLAGL1 TAL1 EPAS1 SMAD4	6.49e-06	908	145	15	19274049
Pubmed	AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival.	PRKAB1 PRKAB2	1.73e-05	2	145	2	32877674
Pubmed	AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.	PRKAB1 PRKAB2	1.73e-05	2	145	2	26023060
Pubmed	Classic bladder exstrophy and adenocarcinoma of the bladder: Methylome analysis provide no evidence for underlying disease-mechanisms of this association.	ISL1 PLAGL1	1.73e-05	2	145	2	31296310
Pubmed	Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo.	KMT2D KMT2A	1.73e-05	2	145	2	26711341
Pubmed	The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.	PTPRD PTPRF	1.73e-05	2	145	2	7665159
Pubmed	AMPK activation of muscle autophagy prevents fasting-induced hypoglycemia and myopathy during aging.	PRKAB1 PRKAB2	1.73e-05	2	145	2	26039451
Pubmed	Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.	KMT2D KMT2A	1.73e-05	2	145	2	24423662
Pubmed	CITED2 Cooperates with ISL1 and Promotes Cardiac Differentiation of Mouse Embryonic Stem Cells.	ISL1 CITED2	1.73e-05	2	145	2	27818139
Pubmed	Expression of the AMP-activated protein kinase beta1 and beta2 subunits in skeletal muscle.	PRKAB1 PRKAB2	1.73e-05	2	145	2	10544261
Pubmed	The role of AMP-activated protein kinase in the expression of the dystrophin-associated protein complex in skeletal muscle.	PRKAB1 PRKAB2	1.73e-05	2	145	2	29401588
Pubmed	Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy.	PRKAB1 SESN2	1.73e-05	2	145	2	32020222
Pubmed	AMPKβ1 and AMPKβ2 define an isoform-specific gene signature in human pluripotent stem cells, differentially mediating cardiac lineage specification.	PRKAB1 PRKAB2	1.73e-05	2	145	2	33454005
Pubmed	Expression of receptor protein tyrosine phosphatase δ, PTPδ, in mouse central nervous system.	MAP2 PTPRD	1.73e-05	2	145	2	27026654
Pubmed	Germline deletion of AMP-activated protein kinase beta subunits reduces bone mass without altering osteoclast differentiation or function.	PRKAB1 PRKAB2	1.73e-05	2	145	2	19723702
Pubmed	Myocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis.	MYOCD MRTFA	1.73e-05	2	145	2	31928221
Pubmed	ASXL1 and SETBP1 mutations and their prognostic contribution in chronic myelomonocytic leukemia: a two-center study of 466 patients.	ASXL1 SETBP1	1.73e-05	2	145	2	24695057
Pubmed	Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2α.	ACO1 EPAS1	1.73e-05	2	145	2	23395173
Pubmed	Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX.	HDAC4 MORC2	1.73e-05	2	145	2	20110259
Pubmed	Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells.	MYOCD MRTFA	1.73e-05	2	145	2	14970199
Pubmed	Histone deacetylase 4 mediates SMAD family member 4 deacetylation and induces 5-fluorouracil resistance in breast cancer cells.	HDAC4 SMAD4	1.73e-05	2	145	2	23817620
Pubmed	SMG1 and CDK12 Link ΔNp63α Phosphorylation to RNA Surveillance in Keratinocytes.	SMG1 CDK12	1.73e-05	2	145	2	34761935
Pubmed	Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis.	PRKAB1 PRKAB2	1.73e-05	2	145	2	36543129
Pubmed	The connectivity map links iron regulatory protein-1-mediated inhibition of hypoxia-inducible factor-2a translation to the anti-inflammatory 15-deoxy-delta12,14-prostaglandin J2.	ACO1 EPAS1	1.73e-05	2	145	2	20354189
Pubmed	TOX defines a conserved subfamily of HMG-box proteins.	TOX TOX3	1.73e-05	2	145	2	12697058
Pubmed	Muscle-specific AMPK β1β2-null mice display a myopathy due to loss of capillary density in nonpostural muscles.	PRKAB1 PRKAB2	1.73e-05	2	145	2	24522207
Pubmed	AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.	PRKAB1 PRKAB2	1.73e-05	2	145	2	21896769
Pubmed	Identification of a novel AMP-activated protein kinase beta subunit isoform that is highly expressed in skeletal muscle.	PRKAB1 PRKAB2	1.73e-05	2	145	2	9575201
Pubmed	An ATM/TRIM37/NEMO Axis Counteracts Genotoxicity by Activating Nuclear-to-Cytoplasmic NF-κB Signaling.	RAN IKBKG NUP155	1.97e-05	13	145	3	30254148
Pubmed	Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.	HDAC4 SETBP1 SLC14A2	1.97e-05	13	145	3	22693459
Pubmed	Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure.	RAN NUP155 NUP210 KMT2A	2.36e-05	40	145	4	37516964
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	CDK12 IKBKG MORC2 ACIN1 PSME3	2.95e-05	85	145	5	16051665
Pubmed	A "double adaptor" method for improved shotgun library construction.	TOM1L2 ZXDC C5orf22 HDAC4 PLXDC1 CCDC57 CREB3L1 TIAM1 PAK3 RIMS2 EPAS1	3.11e-05	574	145	11	8619474
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM49 TRIM49C TRIM49B	3.11e-05	15	145	3	19703589
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 ASXL1 TOX CDK12 SETBP1 CACNA1G MRTFA	4.68e-05	225	145	7	12168954
Pubmed	MYOCD and SMAD3/SMAD4 form a positive feedback loop and drive TGF-β-induced epithelial-mesenchymal transition in non-small cell lung cancer.	MYOCD SMAD4	5.16e-05	3	145	2	32029901
Pubmed	Myocardin-related transcription factor contributes to renal fibrosis through the regulation of extracellular microenvironment surrounding fibroblasts.	MYOCD MRTFA	5.16e-05	3	145	2	37289107
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRD PTPRF	5.16e-05	3	145	2	31985401
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRD PTPRF	5.16e-05	3	145	2	20139422
Pubmed	Initial trajectories of sensory axons toward laminar targets in the developing mouse spinal cord.	MAP2 ISL1	5.16e-05	3	145	2	9100133
Pubmed	Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.	KMT2D KMT2A	5.16e-05	3	145	2	26902498
Pubmed	Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.	PTPRD PTPRF	5.16e-05	3	145	2	33656439
Pubmed	Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.	KMT2D KMT2A	5.16e-05	3	145	2	23932714
Pubmed	EGFR signaling leads to downregulation of PTP-LAR via TACE-mediated proteolytic processing.	PTPRF ADAM17	5.16e-05	3	145	2	16478662
Pubmed	Prognostic impact of specific molecular profiles in pediatric acute megakaryoblastic leukemia in non-Down syndrome.	KMT2A MRTFA	5.16e-05	3	145	2	28063190
Pubmed	Cezanne regulates E2F1-dependent HIF2α expression.	OTUD7B EPAS1	5.16e-05	3	145	2	26148512
Pubmed	Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer.	TOX TOX3	5.16e-05	3	145	2	17529974
Pubmed	Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor.	MYOCD MRTFA	5.16e-05	3	145	2	11439182
Pubmed	HDAC4 stimulates MRTF-A expression and drives fibrogenesis in hepatic stellate cells by targeting miR-206.	HDAC4 MRTFA	5.16e-05	3	145	2	28548935
Pubmed	ADAM10 and ADAM17 are degraded by lysosomal pathway via asparagine endopeptidase.	LGMN ADAM17	5.16e-05	3	145	2	33383559
Pubmed	Generation of a Cre knock-in into the Myocardin locus to mark early cardiac and smooth muscle cell lineages.	ISL1 MYOCD	5.16e-05	3	145	2	25174608
Pubmed	SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS.	ASXL1 SETBP1	5.16e-05	3	145	2	25306901
Pubmed	OASIS modulates hypoxia pathway activity to regulate bone angiogenesis.	CREB3L1 EPAS1	5.16e-05	3	145	2	26558437
Pubmed	Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation.	MYOCD MRTFA	5.16e-05	3	145	2	17363709
Pubmed	The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.	ACO1 EPAS1	5.16e-05	3	145	2	23395174
Pubmed	Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function.	PRKAB1 PRKAB2	5.16e-05	3	145	2	27411013
Pubmed	Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.	PTPRD PTPRF	5.16e-05	3	145	2	25703008
Pubmed	Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.	PTPRD PTPRF	5.16e-05	3	145	2	9784606
Pubmed	TRIM41 is required to innate antiviral response by polyubiquitinating BCL10 and recruiting NEMO.	TRIM41 IKBKG	5.16e-05	3	145	2	33640899
Pubmed	MLL histone methylases regulate expression of HDLR-SR-B1 in presence of estrogen and control plasma cholesterol in vivo.	KMT2D KMT2A	5.16e-05	3	145	2	23192982
Pubmed	IRP1 regulates erythropoiesis and systemic iron homeostasis by controlling HIF2α mRNA translation.	ACO1 EPAS1	5.16e-05	3	145	2	23777768
Pubmed	Co-occurring mutations in ASXL1, SRSF2, and SETBP1 define a subset of myelodysplastic/ myeloproliferative neoplasm with neutrophilia.	ASXL1 SETBP1	5.16e-05	3	145	2	37354804
Pubmed	Metformin Prevents Nigrostriatal Dopamine Degeneration Independent of AMPK Activation in Dopamine Neurons.	PRKAB1 PRKAB2	5.16e-05	3	145	2	27467571
Pubmed	RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding.	MYOCD MRTFA	5.16e-05	3	145	2	18025109
Pubmed	Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice.	MYOCD MRTFA	5.16e-05	3	145	2	23103763
Pubmed	Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.	IKBKG EPAS1	5.16e-05	3	145	2	15653678
Pubmed	Coupling HDAC4 with transcriptional factor MEF2D abrogates SPRY4-mediated suppression of ERK activation and elicits hepatocellular carcinoma drug resistance.	HDAC4 SPRY4	5.16e-05	3	145	2	34339801
Pubmed	Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes.	PRKAB1 PRKAB2	5.16e-05	3	145	2	16505254
Pubmed	Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.	KMT2D KMT2A	5.16e-05	3	145	2	30315824
Pubmed	ASXL1 mutations are frequent and prognostically detrimental in CSF3R-mutated chronic neutrophilic leukemia.	ASXL1 SETBP1	5.16e-05	3	145	2	25850813
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DOCK1 TROAP CDK12 MORC2 EPS15L1 RACGAP1 ACIN1 KIF13A MRTFA BEGAIN	5.30e-05	503	145	10	16964243
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CBLL1 RAN WBP11 SLK HDAC4 EPS15L1 PTPRD SSH1 PTPRN2 STON2 ZSCAN18 RACGAP1 PAK3 BEGAIN	5.39e-05	963	145	14	28671696
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	UBL7 DOCK1 ISYNA1 HJURP ZNF395 SSH1 SF3B2	5.68e-05	232	145	7	25515538
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RAN AARS1 C5orf22 PTPRD NUP155 PTPRF SSH1 WDR97 PTPRN2 NUP210 PRKAB1 PSME3 ESPL1 SF3B2	6.08e-05	974	145	14	28675297
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM49 TRIM49C TRIM49B	6.55e-05	19	145	3	22144910
Pubmed	High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.	HDAC4 SLC30A5 SSH1 FAM20B	7.80e-05	54	145	4	26273529
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK1 HDAC4 HJURP OTUD7B ZNF469 NUP155 SETBP1 STON2 MRTFA	8.57e-05	430	145	9	35044719
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ATP6V1B2 SLK MORC2 F5 PHC2 EPS15L1 MED4 RACGAP1 KMT2A PSME3 L3MBTL3	8.81e-05	645	145	11	25281560
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2D KDM2B KMT2A	8.93e-05	21	145	3	27626377
Pubmed	AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.	MAP2 PRKAB1 PRKAB2	8.93e-05	21	145	3	19217427
Pubmed	Human transcription factor protein interaction networks.	SMG1 ASXL1 WBP11 SLK HIVEP1 IKBKG MORC2 KMT2D MED4 ZSCAN18 KDM2B RACGAP1 KMT2A YY1AP1 PSME3 TAL1 L3MBTL3	1.01e-04	1429	145	17	35140242
Pubmed	Translational repression of HIF2α expression in mice with Chuvash polycythemia reverses polycythemia.	ACO1 EPAS1	1.03e-04	4	145	2	29480820
Pubmed	Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions.	KMT2D KMT2A	1.03e-04	4	145	2	22863532
Pubmed	KDM5A noncanonically binds antagonists MLL1/2 to mediate gene regulation and promotes epithelial to mesenchymal transition.	KMT2D KMT2A	1.03e-04	4	145	2	37722486
Pubmed	Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP-activated protein kinase.	PRKAB1 PRKAB2	1.03e-04	4	145	2	8621499
Pubmed	AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.	PRKAB1 PRKAB2	1.03e-04	4	145	2	15058305
Pubmed	Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.	GRHL2 KMT2D	1.03e-04	4	145	2	35013237
Pubmed	Rac1 and AMPK Account for the Majority of Muscle Glucose Uptake Stimulated by Ex Vivo Contraction but Not In Vivo Exercise.	PRKAB1 PRKAB2	1.03e-04	4	145	2	28389470
Pubmed	Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin.	PRKAB1 PRKAB2	1.03e-04	4	145	2	24185692
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRD PTPRF PTPRN2	1.44e-04	21	89	3	813
GeneFamily	PDZ domain containing	PCLO FRMPD1 TIAM1 RIMS2 AHNAK2	9.25e-04	152	89	5	1220
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM49 TRIM41 TRIM49C TRIM49B	1.24e-03	95	89	4	59
GeneFamily	Zinc fingers CXXC-type	KDM2B KMT2A	1.53e-03	12	89	2	136
GeneFamily	Ring finger proteins	CBLL1 TRIM49 TRIM41 TRIM49C RNF212 TRIM49B	2.37e-03	275	89	6	58
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_GHRL_POS_NE_PRECURSOR_CELL	TOM1L2 TOX MAP2 PCLO ZDHHC14 RFX6 ISL1 ORAI2 NACAD PTPRN2 PDE8B STON2 RIMS2	7.64e-07	429	144	13	M45694
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RFX6 ISL1 ITGA7 WDR97 NYNRIN DISP3 RIMS2	1.05e-06	162	145	7	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	(5)_Epithelial_cells-(5)_Glands_mucous\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	TOX F5 CREB3L1 ADGRG2 PTPRN2 PDE8B TOX3	2.12e-06	180	145	7	a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PLXDC1 ABHD2 F5 HMCN2 PTPRD SETBP1 AHNAK2	3.72e-06	196	145	7	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	LGMN ZNF469 NUP210 PRKAB1 STON2 KDM2B AHNAK2	3.72e-06	196	145	7	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|367C / Donor, Lineage, Cell class and subclass (all cells)	TRIM41 ZNF683 NUP155 NLRC5 PRKCQ OAZ3	1.47e-05	161	145	6	f470b662566131dfe69a2fd01186ac8491196396
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TROAP HJURP GPR137C NUP210 RACGAP1 ESPL1	1.75e-05	166	145	6	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	AT1-AT2_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	TOX MAP2 PCLO LAMA5 PTPRF AHNAK2	1.94e-05	169	145	6	815474855a70498a74e52f6583113c63b7267a0c
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TROAP HJURP PTPRD ZSCAN18 RACGAP1 DHTKD1	1.94e-05	169	145	6	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	droplet-Lung-nan-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L ABHD2 HJURP TBC1D10C GPR137C PRKCQ	1.94e-05	169	145	6	df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L ABHD2 HJURP TBC1D10C GPR137C PRKCQ	1.94e-05	169	145	6	f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TOX RPS27 TBC1D10C NLRC5 RACGAP1 PRKCQ	2.29e-05	174	145	6	7c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCell	droplet-Fat-Scat-21m-Lymphocytic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOX NFKBID RPS27 TBC1D10C NUP210 PRKCQ	2.36e-05	175	145	6	921168c3245cfd6e3fb6abc214b4b112045ac8d0
ToppCell	droplet-Fat-Scat-21m-Lymphocytic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOX NFKBID RPS27 TBC1D10C NUP210 PRKCQ	2.36e-05	175	145	6	fe10d18c5900871b43de793a3715118ae1a3a3c9
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	TOM1L2 AARS1 HDAC4 KMT2A KIF13A DHTKD1	2.52e-05	177	145	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TOX RPS27 TBC1D10C NLRC5 RACGAP1 PRKCQ	2.52e-05	177	145	6	d6b7d387e7485ff52ce27f51df8b8050f49fd941
ToppCell	(5)_Glands_mucous\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	F5 CREB3L1 ADGRG2 PTPRN2 PDE8B TOX3	2.60e-05	178	145	6	f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MMS22L TROAP HJURP GPR137C RACGAP1 ESPL1	2.68e-05	179	145	6	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TROAP HJURP CREB3L1 HMCN2 RACGAP1 ESPL1	2.68e-05	179	145	6	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 PCLO RFX6 ISL1 PTPRN2 ZSCAN18	2.77e-05	180	145	6	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MMS22L TROAP ABHD2 GPR137C RACGAP1 ESPL1	2.85e-05	181	145	6	cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCLO RFX6 ISL1 ADGRG2 PDE8B RIMS2	2.85e-05	181	145	6	cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MMS22L TROAP ABHD2 GPR137C RACGAP1 ESPL1	2.85e-05	181	145	6	74311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell	Control-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	ASXL1 IKZF2 HIVEP1 TOX F5 TIAM1	3.23e-05	185	145	6	e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	HIVEP1 TOX ITGA7 UBE4A PTPRN2 KDM2B	3.33e-05	186	145	6	76cbc3610aedf8c19c17ad5faf6ef5e8980b6af5
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 MAP2 DBNDD2 ITGA7 PDE8B SPRY4	3.43e-05	187	145	6	a12f383b02b07af32cc53a154685df8dba8fbd3f
ToppCell	facs-Heart-LA-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 MAP2 DBNDD2 ITGA7 PDE8B SPRY4	3.43e-05	187	145	6	c40c152fa14e6afc9188549534b64ccbaded56b3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 MAP2 ITGA7 KCNT2 MYOCD EPAS1	3.43e-05	187	145	6	48bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCell	droplet-Pancreas\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 PCLO RFX6 ISL1 PTPRN2 PAK3	3.43e-05	187	145	6	5f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 MAP2 ITGA7 KCNT2 MYOCD EPAS1	3.43e-05	187	145	6	958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 TOX GRHL2 SETBP1 TOX3 SLC14A2	3.64e-05	189	145	6	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	18-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	PCLO RFX6 F5 NUP210 RIMS2 ESPL1	3.64e-05	189	145	6	144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	MAP2 ZDHHC14 HMCN2 KCNT2 MYOCD KIF13A	3.64e-05	189	145	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 MAP2 ITGA7 KCNT2 MYOCD EPAS1	3.64e-05	189	145	6	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	CF-Lymphoid-B_cell\|CF / Disease state, Lineage and Cell class	PMS2P1 ASXL1 TOX ZDHHC14 SETBP1 NUP210	3.75e-05	190	145	6	374d8fd63c733178acab07682ed1519693efab45
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IKZF2 RFX6 GRHL2 PTPRF NUP210 STON2	3.75e-05	190	145	6	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABHD2 ZDHHC14 PDE8B SPRY4 CACNA1G KIF13A	3.75e-05	190	145	6	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	COPD-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	ASXL1 IKZF2 HIVEP1 TOX F5 TIAM1	3.86e-05	191	145	6	3ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V1B2 MAP2 ISL1 PTPRN2 PAK3 RIMS2	3.86e-05	191	145	6	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 PCLO RFX6 ISL1 PTPRN2 PAK3	3.86e-05	191	145	6	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP6V1B2 MAP2 ISL1 PTPRN2 PAK3 RIMS2	3.86e-05	191	145	6	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	IKZF2 TOX TBC1D10C NUP210 NLRC5 PRKCQ	3.97e-05	192	145	6	69a2b04f03a1b82d067018379f7b8a116e954040
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF2 TOX F5 TBC1D10C PRKCQ L3MBTL3	3.97e-05	192	145	6	d85a785a12076e34c404171363a647f318926b18
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-suprabasal_interpapillary\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF2 SLC39A11 CREB3L1 TIAM1 TTC22 EPAS1	3.97e-05	192	145	6	44cb225392c8d07150955ecf203fbdf6021c9790
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 DBNDD2 ITGA7 GRHL2 PDE8B EPAS1	3.97e-05	192	145	6	88472b99970ba0decbf87164fc241a1c77b3b389
ToppCell	BAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF2 TOX F5 TBC1D10C PRKCQ L3MBTL3	3.97e-05	192	145	6	230f3090607a62bb6d1e1f4b0341ee96d93f1c00
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RAN MAP2 TROAP HJURP RACGAP1 ESPL1	3.97e-05	192	145	6	849ac3c115e6f913e68ca050c308bc4c32cf662b
ToppCell	CF-Lymphoid\|CF / Disease state, Lineage and Cell class	PMS2P1 ASXL1 TOX ZDHHC14 SETBP1 NUP210	4.09e-05	193	145	6	11de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IKZF2 ZNF683 RPS27 CCDC57 TBC1D10C NLRC5	4.21e-05	194	145	6	a7e1445cf7ce7de04a7a11601c66fe8c03a82db6
ToppCell	15-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	ISYNA1 PLXDC1 ZDHHC14 ITGA7 MYOCD EPAS1	4.21e-05	194	145	6	5c1218d239c88082496924653ed2a092dc44a906
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 DBNDD2 ITGA7 GRHL2 PDE8B RIMS2	4.21e-05	194	145	6	52ecec2618c3bb5fdd7fb06b5a40bd6f0aedfe1d
ToppCell	Mild-CD8+_T\|World / Disease group and Cell class	IKZF2 TOX PLXDC1 ZNF683 TBC1D10C KMT2A	4.21e-05	194	145	6	d64c2efb482bcdef9240977eae1023c4191286e7
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	MMS22L TROAP HJURP NUP210 RACGAP1 ESPL1	4.33e-05	195	145	6	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.45e-05	196	145	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF683 RPS27 TBC1D10C KMT2D FAM20B PRKCQ	4.45e-05	196	145	6	511e9846d204b2346b17d1a4142c3bb484b08e32
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 PLXDC1 MAP2 ITGA7 MYOCD EPAS1	4.45e-05	196	145	6	5146976881d79642ebe5dcbcf89e0252713a9ef2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 PLXDC1 MAP2 ITGA7 MYOCD EPAS1	4.45e-05	196	145	6	ebac1d6af7a5732707d82d01285c086b19d8ae62
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SMG1 IKZF2 RPS27 TBC1D10C KMT2A PRKCQ	4.58e-05	197	145	6	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IKZF2 ZNF683 TBC1D10C NLRC5 KMT2A PRKCQ	4.58e-05	197	145	6	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.71e-05	198	145	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	IKZF2 TOX TBC1D10C NLRC5 KMT2A PRKCQ	4.71e-05	198	145	6	1ca6cd8e75891fdfaddbb4a7342eec9ca4d11e5d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.71e-05	198	145	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.71e-05	198	145	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.71e-05	198	145	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ISYNA1 MAP2 ITGA7 HMCN2 KCNT2 MYOCD	4.71e-05	198	145	6	dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.71e-05	198	145	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MMS22L TROAP HJURP ADGRG2 RACGAP1 ESPL1	4.85e-05	199	145	6	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ISYNA1 PLXDC1 KCNT2 PDE8B SPRY4 MYOCD	4.98e-05	200	145	6	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLK PCLO LAMA5 PTPRF EPAS1 AHNAK2	4.98e-05	200	145	6	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ISYNA1 PLXDC1 KCNT2 PDE8B SPRY4 MYOCD	4.98e-05	200	145	6	b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	MAP2 PCLO PTPRN2 SETBP1 PAK3 RIMS2	4.98e-05	200	145	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLXDC1 LAMA5 CREB3L1 CITED2 TIAM1	1.16e-04	146	145	5	47368f981180ca6a8c81a50f7f9430f12456f609
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNT2 DISP3 PAK3 MYOCD DHTKD1	1.24e-04	148	145	5	dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell	MS-CD8-CD8_2\|MS / Condition, Cell_class and T cell subcluster	ISYNA1 PLXDC1 ZNF683 RPS27 DISP3	1.32e-04	150	145	5	01c20d787ce269db0d153e63a600a8d9ead61856
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	HIVEP1 TOX ITGA7 PTPRN2 KDM2B	1.54e-04	155	145	5	a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCell	facs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l26\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP11A1 CREB3L1 PIK3R6 PRKCQ TAL1	1.58e-04	156	145	5	da5cfa8fa9595613f04ce9511f8b42bad34d995a
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PLXDC1 CREB3L1 CITED2 KCNT2 TIAM1	1.58e-04	156	145	5	896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCLO RFX6 PTPRN2 PAK3 RIMS2	1.73e-04	159	145	5	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TOX FRMPD1 NACAD TOX3 SLC14A2	1.73e-04	159	145	5	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF2 TOX TROAP F5 PRKCQ	1.83e-04	161	145	5	b24293fdae9637983fcf4f2d4659a3554e00a53f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma\|TCGA-Brain / Sample_Type by Project: Shred V9	HDAC4 FRMPD1 PTPRN2 PAK3 RIMS2	1.83e-04	161	145	5	5f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IKZF2 TOX TROAP F5 PRKCQ	1.83e-04	161	145	5	eddcbe266d4a84a340fa8f2128d2b7e293968dca
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CBLL1 TOX RNF212 KMT2A L3MBTL3	1.83e-04	161	145	5	2849fbc9611af208241b33da3cd18290aafe426b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC4 TOX FRMPD1 TOX3 NPAP1	1.89e-04	162	145	5	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 GRHL2 CREB3L1 PTPRF TTC22	1.89e-04	162	145	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ISYNA1 ITGA7 MYOCD RIMS2 HR	1.94e-04	163	145	5	8f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TROAP GRHL2 ZNF469 RACGAP1 KIAA1755	2.00e-04	164	145	5	4ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell	10x5'v1-week_14-16-Lymphocytic_NK-T_NK-NK_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ISYNA1 IKZF2 TOX ZNF683 PAK3	2.11e-04	166	145	5	05d3e7f441089d788a192d7fa1ec5c302d1ca202
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 GRHL2 CREB3L1 PTPRF TTC22	2.11e-04	166	145	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCLO RFX6 ISL1 ITGA7 RIMS2	2.17e-04	167	145	5	5accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MMS22L PLXDC1 TROAP RACGAP1 MRTFA	2.24e-04	168	145	5	9b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCell	facs-Heart-LV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOX NFKBID TBC1D10C NUP210 NLRC5	2.24e-04	168	145	5	18c266162a879544c0103d9dff0270af68964f9e
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLXDC1 PCDHGA1 PDE8B SPRY4 NPAP1	2.24e-04	168	145	5	e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MMS22L PLXDC1 TROAP RACGAP1 MRTFA	2.24e-04	168	145	5	4b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8\|TCGA-Thryoid / Sample_Type by Project: Shred V9	IKZF2 HIVEP1 ITGA7 SSH1 L3MBTL3	2.24e-04	168	145	5	00646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MMS22L SPRY4 TAL1 L3MBTL3 EPAS1	2.24e-04	168	145	5	c7021748003e5949f7caf7b3291c5bad294948c1
ToppCell	droplet-Fat-Scat-21m-Lymphocytic-T_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IKZF2 TOX NFKBID RPS27 PRKCQ	2.24e-04	168	145	5	99343f7a76ff70a2252c365d527f9c8ae16b8571
ToppCell	facs-Heart-LV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOX NFKBID TBC1D10C NUP210 NLRC5	2.24e-04	168	145	5	cb1506cd43a4f36f9024cc9b8e5319365498d244
ToppCell	PND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MMS22L PLXDC1 TROAP RACGAP1 MRTFA	2.24e-04	168	145	5	c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLXDC1 PCDHGA1 PDE8B SPRY4 NPAP1	2.24e-04	168	145	5	b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MMS22L TROAP HJURP RACGAP1 ESPL1	2.30e-04	169	145	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
Disease	ATYPICAL MYCOBACTERIOSIS, FAMILIAL, X-LINKED 1 (disorder)	IKBKG ADAM17	2.17e-05	2	138	2	C1970879
Disease	Immunodeficiency without anhidrotic ectodermal dysplasia	IKBKG ADAM17	2.17e-05	2	138	2	C1845117
Disease	Idiopathic pulmonary arterial hypertension	HDAC4 EPAS1 SMAD4	5.36e-05	16	138	3	C3203102
Disease	Adenocarcinoma of large intestine	CDK12 PAK3 PRKCQ NEK11 SMAD4	9.04e-05	96	138	5	C1319315
Disease	monoclonal gammopathy	PTPRD SETBP1 RIMS2 SLC14A2	1.12e-04	53	138	4	EFO_0000203
Disease	Brachydactyly	HDAC4 SMAD4	1.29e-04	4	138	2	C0221357
Disease	alcohol consumption measurement	DOCK1 TOM1L2 MMS22L CDK12 CYP11A1 PCLO ZDHHC14 BBS1 RFX6 CREB3L1 PHC2 SETBP1 DHODH RIMS2 TAL1 SLC14A2	2.37e-04	1242	138	16	EFO_0007878
Disease	azoospermia (implicated_via_orthology)	ISYNA1 PTPRD PTPRF	2.70e-04	27	138	3	DOID:14227 (implicated_via_orthology)
Disease	t-tau measurement	C5orf22 PLXDC1 ZDHHC14 F5 AHNAK2	3.23e-04	126	138	5	EFO_0004760
Disease	free androgen index	REN ZNF469 PTPRF PDE8B NYNRIN RIMS2 L3MBTL3 EPAS1	3.92e-04	374	138	8	EFO_0007005
Disease	Colorectal Carcinoma	MAP2 F5 PTPRD TIAM1 PTPRN2 SETBP1 NPAP1 ACIN1 SESN2 SMAD4 HR	4.79e-04	702	138	11	C0009402
Disease	Bladder Neoplasm	HDAC4 ISL1 KMT2D KMT2A ESPL1	5.23e-04	140	138	5	C0005695
Disease	Malignant neoplasm of urinary bladder	HDAC4 ISL1 KMT2D KMT2A ESPL1	5.41e-04	141	138	5	C0005684
Disease	myelofibrosis (is_implicated_in)	ASXL1 KMT2A	5.97e-04	8	138	2	DOID:4971 (is_implicated_in)
Disease	Pulmonary arterial hypertension	EPAS1 SMAD4	9.53e-04	10	138	2	C2973725
Disease	Degenerative polyarthritis	RAN ATP6V1B2 ACO1 ADGRG2	9.69e-04	93	138	4	C0029408
Disease	Osteoarthrosis Deformans	RAN ATP6V1B2 ACO1 ADGRG2	9.69e-04	93	138	4	C0086743
Disease	prostate carcinoma	TOM1L2 WBP11 SLK IKZF2 RFX6 TNFRSF10B PTPRD SETBP1 MYOCD KIF13A L3MBTL3 SLC14A2	1.01e-03	891	138	12	EFO_0001663
Disease	mental or behavioural disorder	ATP6V1B2 KCNT2 PTPRN2 PRKCQ MRTFA	1.57e-03	179	138	5	EFO_0000677
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP1 SMAD4	1.64e-03	13	138	2	DOID:0050787 (implicated_via_orthology)
Disease	renal sinus adipose tissue measurement	TIAM1 L3MBTL3	1.64e-03	13	138	2	EFO_0004864
Disease	L2 Acute Lymphoblastic Leukemia	IKZF2 KMT2A TAL1	1.67e-03	50	138	3	C0023453
Disease	eosinophil measurement	LGMN IKZF2 SLC39A11 SESN2	1.69e-03	108	138	4	EFO_0803540
Disease	neutrophil-to-lymphocyte ratio	HIVEP1 ZNF395 EPS15L1 NLRC5 KDM2B	1.82e-03	185	138	5	EFO_0008447
Disease	Childhood Acute Lymphoblastic Leukemia	IKZF2 KMT2A TAL1	1.87e-03	52	138	3	C0023452
Disease	ventricular septal defect (is_implicated_in)	ISL1 CITED2	1.90e-03	14	138	2	DOID:1657 (is_implicated_in)
Disease	tetralogy of Fallot (implicated_via_orthology)	DOCK1 CITED2	1.90e-03	14	138	2	DOID:6419 (implicated_via_orthology)
Disease	cerebellum cortex volume change measurement	PTPRD EPAS1	1.90e-03	14	138	2	EFO_0021497
Disease	response to cisplatin, platinum measurement	MMS22L SPATA31C1 PTPRN2	1.98e-03	53	138	3	EFO_0010154, GO_0072718
Disease	Lymphoma, Follicular, Grade 2	ATP6V1B2 KMT2D	2.19e-03	15	138	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	ATP6V1B2 KMT2D	2.19e-03	15	138	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	ATP6V1B2 KMT2D	2.19e-03	15	138	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	ATP6V1B2 KMT2D	2.19e-03	15	138	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	ATP6V1B2 KMT2D	2.19e-03	15	138	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	ATP6V1B2 KMT2D	2.19e-03	15	138	2	C0079758
Disease	hair colour measurement	ASXL1 HDAC4 TRIM41 DNAI3 ZNF469 KMT2D SETBP1 TOX3 L3MBTL3	2.49e-03	615	138	9	EFO_0007822
Disease	decreased susceptibility to hepatitis C infection	PTPRD SPRY4	2.50e-03	16	138	2	EFO_0010101
Disease	Chromosome Aberrations	KMT2A EPAS1	2.50e-03	16	138	2	C0008625
Disease	Blood Coagulation Disorders	F5 SMAD4	2.50e-03	16	138	2	C0005779
Disease	Autosome Abnormalities	KMT2A EPAS1	2.50e-03	16	138	2	C0004403
Disease	Familial primary pulmonary hypertension	HDAC4 SMAD4	2.82e-03	17	138	2	C0340543
Disease	cancer	SLK FRMPD1 RFX6 SPRY4 TOX3 KIF13A MRTFA	2.83e-03	400	138	7	MONDO_0004992
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	IKZF2 KMT2A TAL1	2.95e-03	61	138	3	C1961102
Disease	Myeloid Leukemia	SETBP1 KMT2A	3.16e-03	18	138	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SETBP1 KMT2A	3.16e-03	18	138	2	C0023466
Disease	risk-taking behaviour	MMS22L IKZF2 HIVEP1 TOX MAP2 PHC2 KCNT2 PTPRF PTPRN2 CACNA1G	3.24e-03	764	138	10	EFO_0008579
Disease	Juvenile Myelomonocytic Leukemia	ASXL1 SETBP1	3.52e-03	19	138	2	C0349639
Disease	electrocardiography	SLK HIVEP1 HMCN2 SETBP1 KIAA1755 MYOCD CACNA1G EPAS1	3.57e-03	530	138	8	EFO_0004327
Disease	colorectal adenoma (is_marker_for)	F5 SMAD4	3.90e-03	20	138	2	DOID:0050860 (is_marker_for)
Disease	BRCAX breast cancer	DOCK1 SLC39A11	3.90e-03	20	138	2	EFO_0009443
Disease	Lymphoma, Follicular	ATP6V1B2 KMT2D	3.90e-03	20	138	2	C0024301
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	FRMPD1 ADAM17	4.30e-03	21	138	2	EFO_0000180, Orphanet_391311
Disease	Obsessive-compulsive trait	PTPRD NEK11	4.30e-03	21	138	2	HP_0008770
Disease	hyperglycemia (biomarker_via_orthology)	CYP11A1 EPAS1	4.30e-03	21	138	2	DOID:4195 (biomarker_via_orthology)
Disease	disease	SETBP1 SLC14A2	4.30e-03	21	138	2	EFO_0000408
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGA1 PTPRD MYOCD	4.54e-03	71	138	3	EFO_0007878, EFO_0007979

Protein segments in the cluster

Peptide	Gene	Start	Entry
DEMIHPEGVASLLPP	ACIN1	171	Q9UKV3
MSNPFAHLAEPLDPV	ACO1	1	P21399
LSNLNLSMPPPKFHD	EPS15L1	91	Q9UBC2
AMTNIFQPLAPVAPH	EPAS1	566	Q99814
MLHPECKELPEPNLL	DISP3	1086	Q9P2K9
TMPQEEAAACPPHIL	CDK12	1246	Q9NYV4
LPVDPLAAPSAMAAA	CREB3L1	136	Q96BA8
EASPEMHPAARLSPQ	BEGAIN	551	Q9BUH8
SLHLPLSPGLPDSME	ALX3	131	O95076
PLMLVNAADDPLVHE	ABHD2	336	P08910
SRLLHSPPDMLAPLA	ADGRG2	406	Q8IZP9
DPALLPEPNHVMLNH	PRKAB2	226	O43741
VTMLPNPSHLEAVNP	DHTKD1	281	Q96HY7
DPIHPQLMLESPDDI	DNAI3	386	Q8IWG1
MSIISAQDLPHFPGP	CDHR4	166	A6H8M9
LPLEKVLPPAHDDSM	ASXL1	1116	Q8IXJ9
DPLHPSSTDMALVPR	HJURP	216	Q8NCD3
ALAPPEVVMDPALAA	RAN	181	P62826
QGMPDHLLPLLENPV	RFX6	296	Q8HWS3
MDPEPQTFHPVLSLL	ISYNA1	446	Q9NPH2
INASPIMDHDPRNPA	PTPRN2	801	Q92932
MSAELNVPIDPSAPA	ORAI2	1	Q96SN7
QPPLSPLELMEASEH	L3MBTL3	541	Q96JM7
HPLEMPICAFQLPDL	OTUD7B	126	Q6GQQ9
AEHPGLSDFMPLPVL	NUP210	1461	Q8TEM1
SALNHSSKPLPMAPE	PAK3	26	O75914
MCHLPEPELNKERPS	PRKCQ	356	Q04759
DHPALPPLDNVIFMV	OAZ3	206	Q9UMX2
TALPLQVAPSAVPMD	HDAC4	36	P56524
TALHMAAALPPGPAQ	NFKBID	246	Q8NI38
MDPPSLDTAIQHALA	KIAA1755	1	Q5JYT7
PHAVLQQEKELPAPM	MMS22L	976	Q6ZRQ5
VALECQSHAMPPPVL	HMCN2	2096	Q8NDA2
PHLNGPMTDTAPLLF	GPR137C	396	Q8N3F9
AQAILLPQPPNMLDH	C20orf203	11	Q8NBC4
IHMAFAPVTPALPSD	HR	776	O43593
DHPPSSVIALPMKEQ	PCLO	2341	Q9Y6V0
HSHLAMPITINDVPP	PDE8B	531	O95263
EDPLLPPAMGEHTVN	COG8	296	Q96MW5
ENLPESQPIPSMDLH	NEK11	436	Q8NG66
MLSHLDLEQAPPPHR	MYOCOS	46	A0A1B0GUC4
PAMLHLPSEQGAPET	IKBKG	36	Q9Y6K9
PIVLLLDNPPDMHFL	KCNT2	751	Q6UVM3
EASPAMLPVQPAELT	PMS2P1	396	A4D2B8
LPLTHAQDLTPAMSP	LAMA5	1246	O15230
MLPPNHSSDFLLEPP	MED4	231	Q9NPJ6
ILMGLPHAPALDAPL	OR10G8	11	Q8NGN5
EALHPLMQHPPSTIA	IKZF2	331	Q9UKS7
FNAHEILPGPLSPMQ	MYOCD	851	Q8IZQ8
PDHAPGQSVALLPNM	NLRC5	421	Q86WI3
PDLSELLMVSAPNNP	NUP155	41	O75694
LMKPPSPEHQSLDTQ	MORC2	851	Q9Y6X9
PHEDIRAPPAELSMA	CBLL1	256	Q75N03
PLQPEMPDLSHLTEE	RIMS2	21	Q9UQ26
SLIAPPTAPSLAHMD	MLXIP	381	Q9HAP2
LAALQPCSPEHMAEP	ESPL1	531	Q14674
MPDLHSQPVLFIPDV	GRHL2	471	Q6ISB3
PPDSLPLDDGAAHVM	KDM2B	1051	Q8NHM5
HLDDPSLPINPLSML	DOCK1	1511	Q14185
LELEMKTLSPQPHSP	CACNA1G	1871	O43497
GMDNHLEELSLPVPT	DBNDD2	191	Q9BQY9
QPSSMLEPLALHPPL	FRMPD1	746	Q5SYB0
FDSHPDLLIPVNMPA	C5orf22	51	Q49AR2
PQPASPLMHIEGFLA	DDX12P	576	Q92771
EMEALSHQIPPPIQT	CCDC57	541	Q2TAC2
FHTSVPMLNLPPDLF	CYP11A1	241	P05108
SGMLPNAVLPPSLDH	KMT2A	1786	Q03164
LELMVTNLPSDPAQP	ITGA7	731	Q13683
PLPALPAAAATFLME	BBS1	81	Q8NFJ9
DLLMPHLGAAEDPQT	SLC39A11	96	Q8N1S5
MRDHPPIPITDLADN	PTPRF	1326	P10586
MLAVHTEPAAPEVPL	NYNRIN	576	Q9P2P1
MASHPPIPILELADH	PTPRD	1331	P23468
ADGPQHPEMVLQSPL	PCDHGA1	186	Q9Y5H4
PPGMETHIPVLFLDL	KIF13A	1166	Q9H1H9
ADILEPSPHPDMLCF	SESN2	301	P58004
MPNDDITHPIPDLTG	ATP6V1B2	356	P21281
SSDQRLLDHMAPPPV	SPRY4	106	Q9C004
LLDHMAPPPVADQAS	SPRY4	111	Q9C004
DPDTAHPALMLSPDR	TRIM41	436	Q8WV44
ESVLLHMPQPLNPEL	TRIM49	256	P0CI25
MEEPPQEALAEPLKH	TEX55	1	Q96M34
AAQPMQPLPESLASL	PLAGL1	271	Q9UM63
IEMAEIEPPHHELNP	SLK	226	Q9H2G2
MPLFADLSQIPLTPD	F5	1391	P12259
AAEASMAPPHLVLLN	TAL1	21	P17542
LCTLAIHAMDIPPPT	REN	361	P00797
CPAIHKLAEMPPSLD	PIK3R6	496	Q5UE93
LDEVLHTMPIADPQP	SMAD4	536	Q13485
HLVPQDLDIPNPMEA	SMG1	2826	Q96Q15
LMPTLQGLLDPESAH	DHODH	41	Q02127
HPARPLQMAAEPISA	ISL1	151	P61371
HEPMEDAAPIVSPLA	SPATA31C1	151	P0DKV0
PPMVQLACHPNLDKL	CYB5R1	281	Q9UHQ9
LPSAHDFLSLPIMVP	NPAP1	786	Q9NZP6
AHAVPNPDPVTMLQD	RACGAP1	506	Q9H0H5
PAPAPSAQMDLEHPL	MRTFA	696	Q969V6
PPHQETAETALPLTM	STON2	116	Q8WXE9
DPAALHELGPLVMPS	SSH1	861	Q8WYL5
ISCDPALLPEPNHVM	PRKAB1	221	Q9Y478
APQSAIHMDLPPERD	AHNAK2	4996	Q8IVF2
PSAPAAPKLDHQRMD	ADAM17	746	P78536
AHVPAAMLPPNVIDT	CITED2	206	Q99967
TQIHSDMNLPVPDPI	PSME3	56	P61289
DMNLPVPDPILLTNS	PSME3	61	P61289
LPPHSSAPDRLESME	RNF212	146	Q495C1
PMEDAAPILSLLASP	SPATA31A3	141	Q5VYP0
MATEHPEPPKAELQL	SF3B2	1	Q13435
ALQPSSEAHAMPLGP	PHC2	386	Q8IXK0
SEAHAMPLGPVTPAL	PHC2	391	Q8IXK0
GPMEPLVLVAHSDIP	ZXDC	561	Q2QGD7
GENISLNPDLPHQPM	ZNF135	166	P52742
VSDIPNLANHKMPPA	TIAM1	261	Q13009
PIFLNTIDPSHPMAK	AARS1	51	P49588
APPQLVHMAAAGIPS	SAGE1	131	Q9NXZ1
GPVAAVLLMHLPPEE	TBC1D10C	181	Q8IV04
LMVVSPAEPHSLAPE	WDR97	1401	A6NE52
ESVLLHMPQPLNPEL	TRIM49C	256	P0CI26
SAMAHDPISPVLSDP	FAM20B	356	O75063
SEPQQPAPAMKSHLI	ZNF395	451	Q9H8N7
DPNMLDTLVPAHPAL	UBL7	171	Q96S82
DSHLMPSPAPVAQPL	TROAP	301	Q12815
NMLSPGESEHLLEPA	TNFRSF10B	301	O14763
MPDVLLPFQALSDPL	TOX3	81	O15405
EAPPSEAMTLPKDAH	MAP2	381	P11137
PPASMPNLAEATLAD	ZDHHC14	411	Q8IZN3
LEEVSPMLPSHFPDL	ZNF469	1476	Q96JG9
LPIPSTPEDKAHMNV	YY1AP1	671	Q9H869
PLAAPQCHTLLAPEM	FTSJ1	306	Q9UET6
HMDPLLLPGELASPS	ZSCAN18	156	Q8TBC5
LIDPPELDTHMLTPV	SLC30A5	511	Q8TAD4
LSDAFMILNPSPDVP	PLXDC1	256	Q8IUK5
ESVLLHMPQPLNPEL	TRIM49B	256	A6NDI0
AVMPHLDQTPNPLVS	UBE4A	686	Q14139
VESIPLPDMPHAPSN	WBP11	136	Q9Y2W2
LPDMPHAPSNILIQD	WBP11	141	Q9Y2W2
FPMADLDALSPIHTP	TOM1L2	151	Q6ZVM7
PPRLMANSPSHLCEI	SETBP1	831	Q9Y6X0
DTHPALPLLEMPEEK	SLC14A2	36	Q15849
HLEMQLNFEPRSPAP	TTC22	26	Q5TAA0
PSAEVALLMHPAPGA	UHRF1BP1	876	Q6BDS2
LPFHPQNMDLPEITV	TOX	106	O94900
IDSMSNSHPLLPPEL	HIVEP1	1606	P15822
MPLAKDLLHPSPEEE	RPS27	1	P42677
SDPGVLELPPIQMEH	SIGLEC11	416	Q96RL6
ADSDPNLDPLMNPHI	ZFPL1	291	O95159
LPSDQCPHLLMLPQD	ZNF683	211	Q8IZ20
LSAPGPAQAMSLPHE	KMT2D	3286	O14686
HLDLTPSPDVPLTIM	LGMN	301	Q99538
LPQDSAMTAPLPLQD	NACAD	916	O15069