Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmethylated histone binding

CHD1 L3MBTL1

4.37e-0386232GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

CHD1 L3MBTL1

4.57e-0388232GO:0140034
MousePhenoshort sperm flagellum

CEP78 CABCOCO1 SPEF2

3.82e-0563153MP:0009239
DomainTCEAL1

TCEAL4 TCEAL1 TCEAL8

1.56e-079243IPR010370
DomainBEX

TCEAL4 TCEAL1 TCEAL8

6.72e-0714243PF04538
DomainTF_A-like/BEX

TCEAL4 TCEAL1 TCEAL8

6.72e-0714243IPR021156
Pubmed

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.

TCEAL4 TCEAL1 TCEAL8

5.79e-072424316221301
Pubmed

Genomic structure and chromosomal localization of TCEAL1, a human gene encoding the nuclear phosphoprotein p21/SIIR.

TCEAL1 TCEAL8

2.74e-06424210051408
Pubmed

Exosomal RNF157 mRNA from prostate cancer cells contributes to M2 macrophage polarization through destabilizing HDAC1.

FXR2 CHD1

4.56e-06524236263220
Pubmed

Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions.

TCEAL1 TCEAL8

8.61e-052024233100228
Pubmed

L3MBTL1, a histone-methylation-dependent chromatin lock.

CHD1 L3MBTL1

1.25e-042424217540172
Pubmed

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle.

FXR2 CHD1

1.71e-042824228655764
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

FXR2 N4BP2 TFB2M ZNF185 CAST

2.53e-0485324528718761
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

FXR2 DNAAF10 CHD1 TFB2M LRRFIP1 CAST

3.21e-04141524628515276
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

PDCD11 LRRFIP1 POTEJ

3.57e-0420224324639526
Pubmed

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

RYR3 PROX1

5.48e-045024227597886
InteractionTCEAL2 interactions

TCEAL4 LRRFIP1 TCEAL1

2.95e-0624243int:TCEAL2
CytobandEnsembl 112 genes in cytogenetic band chrXq22

TCEAL4 TCEAL1 TCEAL8

9.87e-05172243chrXq22
CytobandXq22.1

TCEAL1 TCEAL8

2.33e-0443242Xq22.1
GeneFamilyTranscription elongation factor A like family

TCEAL4 TCEAL1 TCEAL8

3.87e-0891531216
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

TCEAL4 RYR3 TCEAL1

3.96e-0512424357f3335f751868a768934c757b06a6378148dc9e
ToppCellControl-MAIT|Control / Disease group and Cell class

DNAAF10 SPEF2 CAST

1.05e-04172243552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABCOCO1 SPEF2 ZNF185

1.20e-04180243babbdc9d3127c62c8db1ce33e0be61669e004893
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABCOCO1 SPEF2 ZNF185

1.20e-041802432b8447c3487b0f29e1d5ded980fe5a96dffd7a9e
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CDCP1 POTEJ PROX1

1.26e-041832438820cfed27b292bc0bc9cde4005219ed41900552
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABCOCO1 SPEF2 ZNF185

1.26e-0418324318040d0653286071df959513c63d94b555a5d00a
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF3 TCEAL4 TCEAL1

1.26e-0418324361a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CABCOCO1 SPEF2 ZNF185

1.26e-041832436ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CABCOCO1 TCEAL4 TCEAL1

1.28e-04184243590fb32bb1f348ea5fa2aece30ebe1e212512991
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CDCP1 POTEJ PROX1

1.34e-0418724398477ba04a42a8da80a72f41a182429f46283595
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCP1 LRRFIP1 CAST

1.38e-04189243c502f0cf16fac9f09891d288dcf0149b9eee9d10
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

CDCP1 TCEAL4 RYR3

1.38e-041892432157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CDCP1 POTEJ PROX1

1.41e-041902432375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CDCP1 POTEJ PROX1

1.41e-041902435f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDCD11 SPEF2 CAST

1.41e-0419024369c5c4d5f4fb6e5ae2c9dbf9d209faf093c3f769
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

CEP78 CABCOCO1 DNAAF10

1.43e-0419124337cf121e6e80760c8519075b7845b9029958a988
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEP78 CABCOCO1 SPEF2

1.43e-04191243683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CDCP1 POTEJ PROX1

1.47e-041932438603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CDCP1 POTEJ PROX1

1.52e-041952435f33ece997f074598b4201ff74f592ee07c86a06
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CDCP1 LRRFIP1 CAST

1.59e-04198243963f028bf5491fa2b38982828a32ab96dcc34bf4
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast|Erythro-cells / Lineage, cell class and subclass

TCEAL4 LRRFIP1 TCEAL8

1.61e-04199243a2139673fecc7d84a46fe21149def649884f669e
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-NK_CD56bright|Int-URO / Disease, condition lineage and cell class

CDCP1 CEP78 TCEAL8

1.63e-04200243776b6590e21dbd80b6679433727070e06bf01f0f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal|GW08 / Sample Type, Dataset, Time_group, and Cell type.

SPEF2 ZNF185 CAST

1.63e-04200243e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
Diseasephosphate measurement

NBPF3 RYR3

1.11e-057222EFO_0010968
Diseasebrain cancer (implicated_via_orthology)

PROX1 L3MBTL1

1.71e-0426222DOID:1319 (implicated_via_orthology)
Diseasebody mass index, fasting blood glucose measurement

PROX1 CAST

6.62e-0451222EFO_0004340, EFO_0004465
Diseaseautism spectrum disorder (implicated_via_orthology)

FXR2 CHD1

5.69e-03152222DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MKRLDQEQGPEESQP

CABCOCO1

136

Q8IVU9
NPEVFKLEDKQPGNM

CDCP1

291

Q9H5V8
EDEKPEPKQNALGQM

CEP78

581

Q5JTW2
LFKEPEGEEQEPQEM

CHD1

976

O14646
LEDMREIEKNPPAQG

RBM12

621

Q9NTZ6
MEEEQDLPEQPVKKA

EYA3

1

Q99504
DNDKKNPREEGMVPF

FXR2

331

P51116
DPVANMEPVQGENKR

DNAAF10

151

Q96MX6
AMEKQEEGKDPEGQP

L3MBTL1

236

Q9Y468
RMKKDQEEEEDQGPP

NBPF3

461

Q9H094
EPQDQEDLEPVKKKM

CHFR

246

Q96EP1
RQPDPDENKPMEDKV

CAST

581

P20810
QNEPLDMKEPDEEKS

LRRFIP1

541

Q32MZ4
MPEQDKDPRVQENPD

nan

1

A6NNC1
LMEEEKENQPADPKE

SPEF2

1276

Q9C093
EENEGKPQNMPKAEE

TCEAL8

6

Q8IYN2
REQEMAENKPKREGN

PROX1

316

Q92786
PEKMSQEPEINKDGD

POTEJ

361

P0CG39
EKEFQKLMADPGNPD

TFB2M

231

Q9H5Q4
GQEEVEMPSKEKQQP

PDCD11

1446

Q14690
GKMENEEQPQDERKP

TCEAL4

16

Q96EI5
MDKPRKENEEEPQSA

TCEAL1

1

Q15170
QPPEEEMRHEDKQNK

RYR3

451

Q15413
PPGEEERNNVLKQMK

ZNF185

16

O15231
AECQEQMPKRDPGKE

N4BP2

996

Q86UW6