Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	increased megakaryocyte-erythroid progenitor cell number	SLFN14 SON	3.04e-05	4	32	2	MP:0013704
MousePheno	abnormal megakaryocyte-erythroid progenitor cell number	SLFN14 SON	1.06e-04	7	32	2	MP:0013703
MousePheno	abnormal megakaryocyte-erythroid progenitor cell morphology	SLFN14 SON	1.41e-04	8	32	2	MP:0013702
Domain	SH3_2	DOCK4 MYO7B ARHGAP33	8.85e-04	86	41	3	IPR011511
Domain	SH3_2	DOCK4 MYO7B ARHGAP33	8.85e-04	86	41	3	PF07653
Domain	SH3	DOCK4 UBASH3B MYO7B ARHGAP33	1.26e-03	216	41	4	SM00326
Domain	SH3	DOCK4 UBASH3B MYO7B ARHGAP33	1.26e-03	216	41	4	PS50002
Domain	SH3_domain	DOCK4 UBASH3B MYO7B ARHGAP33	1.35e-03	220	41	4	IPR001452
Domain	PROTEIN_KINASE_ATP	CDC42BPG PHKG1 DDR1 CDK12 TESK2	3.17e-03	459	41	5	PS00107
Domain	Prot_kinase_dom	CDC42BPG PHKG1 DDR1 CDK12 TESK2	4.15e-03	489	41	5	IPR000719
Domain	PROTEIN_KINASE_DOM	CDC42BPG PHKG1 DDR1 CDK12 TESK2	4.30e-03	493	41	5	PS50011
Domain	Kinase-like_dom	CDC42BPG PHKG1 DDR1 CDK12 TESK2	6.39e-03	542	41	5	IPR011009
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TANC2 PALD1 AMBRA1 NUP188 RPAP1 CLCN7 ZNF592 DHX34 CDK12 PIEZO1 ARHGAP33	7.17e-08	1105	43	11	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AMBRA1 NUP188 ZNF592 DHX34 CDK12 PIEZO1	4.55e-05	529	43	6	14621295
Pubmed	A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.	GAGE2B GAGE2A	5.35e-05	9	43	2	7544395
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	TANC2 PPHLN1 CDK12 TOR1AIP1 SON	8.16e-05	361	43	5	30344098
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK4 PALD1 RPAP1 ATP9A SON	1.43e-04	407	43	5	12693553
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	PHKG1 DDR1 NWD2 ATP9A PABPC3	1.85e-04	430	43	5	32581705
Pubmed	Quantitative trait loci for body size components in mice.	FZD10 DDR1 ZNF592	2.47e-04	98	43	3	16783635
Pubmed	An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.	GAGE2B GAGE10	2.80e-04	20	43	2	18179644
Pubmed	Modulation of apical constriction by Wnt signaling is required for lung epithelial shape transition.	BMP1 FZD10	3.40e-04	22	43	2	27913639
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 AMBRA1 NUP188 ZNF592 DHX34 ARHGAP33 SON	4.03e-04	1116	43	7	31753913
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	AMBRA1 DHX34 FBXO31 ARHGAP33	5.60e-04	307	43	4	37499664
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	PPHLN1 NUP188 TOR1AIP1 SON	7.50e-04	332	43	4	25693804
Pubmed	Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.	DOCK4 UBASH3B	7.69e-04	33	43	2	18271526
Pubmed	Tagging genes with cassette-exchange sites.	CDC42BPG CDK12 TOR1AIP1 TM7SF3	7.76e-04	335	43	4	15741177
Pubmed	Systematic identification of pathological lamin A interactors.	TRIM39 CLCN7 DUS3L TOR1AIP1	7.93e-04	337	43	4	24623722
Pubmed	Ion channel expression in the developing enteric nervous system.	KCNA6 CLCN7	9.67e-04	37	43	2	25798587
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PPHLN1 ZNF592 CDK12 SON	1.02e-03	361	43	4	26167880
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CDC42BPG AMBRA1 RPAP1 DHX34 CDK12	1.20e-03	650	43	5	38777146
Coexpression	GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN	TRIM39 NUP188 RPAP1 DUS3L FBXO31 TESK2	6.59e-07	200	41	6	M6208
Coexpression	GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN	NUP188 RPAP1 DUS3L CDK12 PIEZO1	1.47e-05	200	41	5	M6201
Disease	hypertrophic cardiomyopathy	AMBRA1 PARD3B ZNF592	2.87e-04	92	41	3	EFO_0000538
Disease	blood urea nitrogen measurement	PPHLN1 UBASH3B DHX34 SLC14A2 CDK12	3.92e-04	452	41	5	EFO_0004741
Disease	developmental disorder of mental health (implicated_via_orthology)	TANC2 PARD3B	2.13e-03	49	41	2	DOID:0060037 (implicated_via_orthology)
Disease	visceral:abdominal adipose tissue ratio measurement	OPTC SLC14A2	2.39e-03	52	41	2	EFO_0803318
Disease	forced expiratory volume	PARD3B TRIM39 SLC14A2 CDK12 PIEZO1	4.56e-03	789	41	5	EFO_0004314
Disease	depressive symptom measurement, response to antidepressant	OPTC PIEZO1	6.69e-03	88	41	2	EFO_0007006, GO_0036276
Disease	Neurodevelopmental Disorders	TANC2 PARD3B	7.44e-03	93	41	2	C1535926
Disease	Adenocarcinoma of large intestine	PHKG1 CDK12	7.91e-03	96	41	2	C1319315

Protein segments in the cluster

Peptide	Gene	Start	Entry
YRPPELLLGEERYTP	CDK12	901	Q9NYV4
PAYRLLLATYARPPR	DDR1	511	Q08345
LERLPQRINERPPYY	DUS3L	591	Q96G46
PRRFLLPEYLPYAGI	AMBRA1	806	Q9C0C7
LPRPGRPLDLADYTY	BMP1	16	P13497
PPRVRYSFYLPKEPR	ADAMTS15	791	Q8TE58
RPSNPLRVPYLYIAR	NWD2	696	Q9ULI1
ARPRPRPVYTLKEAY	CDC42BPG	1071	Q6DT37
RPLFLQPTYRYHRLP	PALD1	256	Q9ULE6
YPRPTELRVADLRYP	PARD3B	1126	Q8TEW8
SRKPDYRLRLSLPYP	DNAAF2	311	Q9NVR5
YRLRLSLPYPVDDGR	DNAAF2	316	Q9NVR5
LYYPPRPEDLRRSVK	ASMTL	211	O95671
LRLKDFRDAYPRFPP	CLCN7	706	P51798
YRRIYLPPSRPDDLI	FBXO31	286	Q5XUX0
EDIPPLPRRTAYLYA	OPTC	146	Q9UBM4
RSTYRPRPRRYVEPP	GAGE2D;	6	Q9UEU5
RSTYRPRPRRYVEPP	GAGE2A	6	Q6NT46
PLYVLKYLRRRFSPP	ATP9A	1026	O75110
YYPPSQIARLRPSPR	PABPC3	416	Q9H361
QLPPPHYRTLEYLLR	ARHGAP33	431	O14559
IDPARFRYPERPIIF	FZD10	251	Q9ULW2
RERRPSYLPTPHRAY	KCNA6	506	P17658
PPYSVYERTLRRPVP	DOCK4	1901	Q8N1I0
RSTYRPRPRRYVEPP	GAGE10	6	A6NGK3
YFLQRIICPSPRRYP	C3orf80	96	F5H4A9
PALADLPRTYDPRYR	DHX34	91	Q14147
RYEYERIPRERAPPR	PPHLN1	6	Q8NEY8
DPYALRPLRRLIDAY	PHKG1	336	Q16816
LRDLPDTPRRFTFYP	TRIM39	366	Q9HCM9
RPGEIPLRYPRSYRL	SLFN14	521	P0C7P3
YYPRLKALPPIARVT	SPON2	226	Q9BUD6
RSTYRPRPRRYVEPP	GAGE2B	6	Q13066
LRVRFAPYRPPDISL	TANC2	311	Q9HCD6
IRLRRPPLRYPRYEA	TOR1AIP1	191	Q5JTV8
ALPLYPDPVRLIRYS	ZNF592	696	Q92610
RRLLEGLSYYKPPSP	NUP188	41	Q5SRE5
PPLDSIRLPRYVLYL	SMIM44	26	A0A286YF18
PRLRYVLEVTYPGPA	RPAP1	546	Q9BWH6
RRYENKPYFPPRILG	PIEZO1	1761	Q92508
LPREYVLYLRPTGPL	UBASH3B	86	Q8TF42
PPRTVSVLDPYYRPR	TESK2	376	Q96S53
PFPYRYRKPTVELLD	SLC14A2	506	Q15849
SPRPYRIAPRSYRIA	SON	966	P18583
SYRIAPRPYRLAPRP	SON	976	P18583
YHIPPLRERLYGRLT	TM7SF3	536	Q9NS93
RRPLRYPLLYHEDDT	MYO7B	991	Q6PIF6