Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of stem cell differentiation

SOX5 NKX2-5 LTBP3

7.93e-0627303GO:2000738
GeneOntologyBiologicalProcesspositive regulation of mesenchymal stem cell differentiation

SOX5 LTBP3

1.22e-054302GO:2000741
GeneOntologyBiologicalProcessregulation of mesenchymal stem cell differentiation

SOX5 LTBP3

1.12e-0411302GO:2000739
HumanPhenoFifth metacarpal with ulnar notch

LTBP3 FBN1

6.01e-062132HP:0005900
HumanPhenoHoarse voice

DUOX2 NKX2-5 LTBP3 FBN1 ASAH1

2.92e-05159135HP:0001609
DomainTB

LTBP3 FBN1

5.94e-057322PF00683
Domain-

LTBP3 FBN1

7.91e-0583223.90.290.10
DomainTB

LTBP3 FBN1

1.02e-049322PS51364
DomainTB_dom

LTBP3 FBN1

1.02e-049322IPR017878
DomainGlyco_trans_31

B3GALT1 B3GALNT2

3.36e-0416322IPR002659
DomainGalactosyl_T

B3GALT1 B3GALNT2

3.36e-0416322PF01762
DomainEGF_CA

LTBP3 FBN1 CUBN

4.25e-0486323PF07645
DomainEGF_Ca-bd_CS

LTBP3 FBN1 CUBN

6.04e-0497323IPR018097
DomainEGF_CA

LTBP3 FBN1 CUBN

6.41e-0499323PS01187
DomainASX_HYDROXYL

LTBP3 FBN1 CUBN

6.60e-04100323PS00010
DomainEGF_3

RELN LTBP3 FBN1 CUBN

6.66e-04235324PS50026
DomainEGF

RELN LTBP3 FBN1 CUBN

6.66e-04235324SM00181
DomainEGF-type_Asp/Asn_hydroxyl_site

LTBP3 FBN1 CUBN

7.82e-04106323IPR000152
DomainEGF-like_dom

RELN LTBP3 FBN1 CUBN

8.27e-04249324IPR000742
DomaincEGF

LTBP3 FBN1

9.01e-0426322IPR026823
DomaincEGF

LTBP3 FBN1

9.01e-0426322PF12662
DomainEGF_1

RELN LTBP3 FBN1 CUBN

9.03e-04255324PS00022
DomainEGF-like_CS

RELN LTBP3 FBN1 CUBN

9.85e-04261324IPR013032
DomainEGF_2

RELN LTBP3 FBN1 CUBN

1.04e-03265324PS01186
DomainEGF_CA

LTBP3 FBN1 CUBN

1.17e-03122323SM00179
DomainEGF-like_Ca-bd_dom

LTBP3 FBN1 CUBN

1.23e-03124323IPR001881
DomainGrowth_fac_rcpt_

LTBP3 FBN1 CUBN

2.37e-03156323IPR009030
DomainHomeobox_metazoa

NKX2-5 HOXB1

1.04e-0290322IPR020479
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP3 FBN1

8.40e-058252M47850
Pubmed

A Method to Identify p62's UBA Domain Interacting Proteins.

RELN ULK2 FKBP4

2.81e-071433314702098
Pubmed

Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.

LTBP3 FBN1

8.73e-07233226494287
Pubmed

LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.

LTBP3 FBN1

8.73e-07233229625025
Pubmed

Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.

LTBP3 FBN1

8.73e-07233230306291
Pubmed

Embryologic Origin Influences Smooth Muscle Cell Phenotypic Modulation Signatures in Murine Marfan Syndrome Aortic Aneurysm.

NKX2-5 FBN1

2.62e-06333235861960
Pubmed

Geleophysic Dysplasia

LTBP3 FBN1

2.62e-06333220301776
Pubmed

Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier.

PIAS4 NKX2-5

8.72e-06533218579533
Pubmed

Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.

PIAS4 NKX2-5

3.13e-05933221931855
Pubmed

Genome-wide association study of PR interval.

SOX5 NKX2-5

5.73e-051233220062060
Pubmed

Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer.

CUBN FOLH1

5.73e-051233220852008
Pubmed

Cis-regulatory control of corticospinal system development and evolution.

SOX5 RELN

6.77e-051333222678282
Pubmed

SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.

SOX5 RELN

6.77e-051333218840685
Pubmed

Nkx2-5(+)islet1(+) mesenchymal precursors generate distinct spleen stromal cell subsets and participate in restoring stromal network integrity.

NKX2-5 CR2

7.89e-051433223601687
Pubmed

Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.

SOX5 RELN

9.10e-051533219759535
Pubmed

oto is a homeotic locus with a role in anteroposterior development that is partially redundant with Lim1.

NKX2-5 HOXB1

9.10e-051533210529425
Pubmed

SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.

SOX5 RELN

9.10e-051533218215621
Pubmed

Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression.

SOX5 RELN

9.10e-051533223523356
Pubmed

Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling.

FOXI2 HOXB1

1.04e-041633221362415
Pubmed

Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode.

FOXI2 HOXB1

1.64e-042033218495817
Pubmed

Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.

NKX2-5 HOXB1

1.64e-042033225190705
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

NKX2-5 FBN1

1.81e-042133228302382
Pubmed

Retinoic acid regulates differentiation of the secondary heart field and TGFbeta-mediated outflow tract septation.

NKX2-5 HOXB1

1.81e-042133220230754
Pubmed

SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development.

SOX5 RELN

1.81e-042133219657336
Pubmed

Stage-dependent and locus-specific role of histone demethylase Jumonji D3 (JMJD3) in the embryonic stages of lung development.

HOXB1 RELN

1.99e-042233225079229
Pubmed

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

SOX5 FBN1

1.99e-042233227527664
Pubmed

DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex.

SOX5 RELN

2.18e-042333230329130
Pubmed

Tbx3 is required for outflow tract development.

NKX2-5 HOXB1

2.38e-042433218723448
Pubmed

Wnt signals mediate a fate decision between otic placode and epidermis.

FOXI2 HOXB1

2.58e-042533216452098
Pubmed

Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis.

SOX5 RELN

2.80e-042633226387942
Pubmed

Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling.

SOX5 RELN

3.02e-042733233462115
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

NKX2-5 FBN1

3.02e-042733235894043
Pubmed

Lamination of the cerebral cortex is disturbed in Gli3 mutant mice.

SOX5 RELN

3.02e-042733218448089
Pubmed

Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.

CUBN FKBP4

4.81e-043433219197348
Pubmed

The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence.

SOX5 RELN

5.09e-043533220943929
Pubmed

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.

NKX2-5 HOXB1

5.39e-043633233230114
Pubmed

Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex.

SOX5 RELN

6.01e-043833231080058
Pubmed

NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo.

NKX2-5 HOXB1

6.66e-044033226534985
Pubmed

Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.

HOXB1 CUBN ASAH1 FKBP4

7.22e-044323347671812
GeneFamilyBeta 3-glycosyltransferases

B3GALT1 B3GALNT2

3.49e-0424212426
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GALT1 CRISPLD2 LTBP3 FBN1

9.26e-0618033439ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

SOX5 CRISPLD2 LIX1L LTBP3

1.05e-05186334e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CRISPLD2 HOXB1 LTBP3 FBN1

1.17e-051913349bbafdf316c1fa3a9f1ee30d41dd7158b5c97279
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SOX5 CRISPLD2 LTBP3 FBN1

1.40e-0520033467dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

SOX5 CRISPLD2 LTBP3 FBN1

1.40e-05200334a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

CRISPLD2 LTBP3 FBN1 GPR158

1.40e-05200334a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CRISPLD2 LTBP3 FBN1 GPR158

1.40e-0520033409537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 CRISPLD2 HOXB1

1.44e-04138333d5342383c5e52b92c39d7afe76560501be3ea5cd
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 CRISPLD2 HOXB1

1.44e-04138333e2659949944bdf39b23c7275e380a7a937e2726c
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

B3GALT1 SOX5 RELN

1.91e-041523332ff0980dfd8d430cca14649151d856edef115720
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

B3GALT1 STPG1 ZAP70

1.95e-04153333fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

B3GALT1 STPG1 ZAP70

1.95e-041533332482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

CRISPLD2 FBN1 ERV3-1

2.19e-041593333f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 LTBP3 CTTNBP2NL

2.39e-04164333758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

CRISPLD2 DUOX2 FBN1

2.61e-041693336373562ab3b1765060212a6a53d6543e7e942e80
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

2.71e-04171333972fab891135bd755d5526cbc5a963200067b0a6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

2.71e-041713332a77ed79c6f2e700e789c80451a70ecb31639719
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CRISPLD2 HOXB1 FBN1

2.95e-0417633308f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 CRISPLD2 LTBP3

2.99e-04177333b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 CRISPLD2 FBN1

3.04e-0417833327497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRS2 STPG1 FKBP4

3.04e-0417833391bf3c7c05d2e67ee590389a1b36c517d0ed7ebf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IRS2 STPG1 FKBP4

3.04e-04178333be4976bbfd9ebbc568155ede99a07670c43aa372
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GALT1 CRISPLD2 FBN1

3.04e-04178333d348a9550db940d204706529759dc51e30506b5f
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN LTBP3 CUBN

3.04e-04178333b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SOX5 FBN1 CTTNBP2NL

3.09e-041793331ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX5 CRISPLD2 GPR158

3.09e-04179333a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX5 CRISPLD2 FBN1

3.15e-0418033301f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 FBN1 FOLH1

3.20e-04181333269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 FBN1 FOLH1

3.20e-04181333cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 FBN1 FOLH1

3.20e-04181333c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 IRS2 FBN1

3.25e-04182333dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 IRS2 FBN1

3.25e-04182333c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCelldroplet-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUBN PSME4 FOLH1

3.35e-04184333e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

SOX5 CRISPLD2 FBN1

3.41e-04185333a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.46e-0418633335c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.46e-04186333d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 CUBN STPG1

3.63e-04189333cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 CUBN STPG1

3.63e-04189333102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.63e-0418933371397e993a77d70b2eeede240bdfc7660b558987
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

SOX5 CRISPLD2 FBN1

3.63e-0418933344e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.63e-041893334eea4759520c312bd17a681034d8074e47093d2b
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.63e-04189333c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN STPG1 ULK2

3.63e-041893330739baad9a7da511dd3d7249f84299aee88370a1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.63e-04189333c734e5693808a0333139e87bd5be2597a9252afe
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.63e-041893332a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 LTBP3 FBN1

3.63e-041893335a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 CUBN STPG1

3.63e-041893336e83bf855d4771885b60bb8992df2f9b508eef97
ToppCellfacs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 IRS2 LTBP3

3.68e-04190333c7bd087f36321cec61b98657433b4d19d135791f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.68e-041903331f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.68e-041903332306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellfacs-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 IRS2 LTBP3

3.68e-04190333834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.68e-04190333445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.68e-041903339cd147a174017ebda23cc47b6d4552d898acd092
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.68e-041903332e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-0419133339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-04191333a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-04191333cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-0419133304c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-04191333c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-041913331caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-041913333d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-04191333806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.74e-04191333ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.80e-041923339093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CRISPLD2 FBN1

3.80e-04192333162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCelldroplet-Lung-1m-Mesenchymal|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 LTBP3 FBN1

3.80e-0419233301433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 LTBP3 FBN1

3.80e-0419233332acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.80e-041923335105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.80e-04192333a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.80e-04192333d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CRISPLD2 FBN1

3.80e-041923334e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.80e-041923339333aba0d04203ccccad78d82bf6359922f810a7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.80e-041923339ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 LTBP3 FBN1

3.80e-04192333011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.80e-04192333eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRS2 LTBP3 FBN1

3.80e-041923330dc1f46e40346ed0b286e53b106a812441575100
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 LTBP3 CUBN

3.86e-041933332b80991e7ba7640f7ab2139d30e4c54d8e533862
ToppCellLA|World / Chamber and Cluster_Paper

SOX5 CRISPLD2 FBN1

3.86e-04193333d4bf89437216baf489ea0239136dcedf3b6714af
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-04193333ebd090d7801480b3cee45caac3d30cc991836769
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRISPLD2 FBN1 TMEM269

3.86e-04193333b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-0419333322c58032e58730715224d7934968ce92d150b0e8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.86e-04193333f1199518c3626fd29bfce65070dd21a660671213
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-041933330a665531d581d4e3941e29d3f95569da8f166447
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-myofibroblast_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CRISPLD2 LTBP3 CUBN

3.86e-0419333390cfc34c2d0d7c70f071703d35db1d6037961481
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-0419333349600db68ed65cafc67bd45a285b364e4f5f88af
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 FBN1 CTTNBP2NL

3.86e-041933332e72309607902dabe3218888b22a77fe941f3570
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-0419333324ce1f37cca655415410d2403a52d1ebb3332280
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-04193333d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-04193333573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.86e-0419333345b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

SOX5 CRISPLD2 FBN1

3.86e-04193333e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 CRISPLD2 FBN1

3.92e-04194333ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B3GALT1 CRISPLD2 LTBP3

3.92e-041943337826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CRISPLD2 IRS2 FBN1

3.92e-04194333e93de9428c986b8943fc169258847c650cfab0e5
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX5 CRISPLD2 FBN1

3.92e-041943336e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN IRS2 PSME4

3.92e-0419433311709704079f24a730476572dc2f01e9d2226e2c
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

CRISPLD2 IRS2 FBN1

3.92e-04194333014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX5 CRISPLD2 FBN1

3.92e-041943332d66091097e106c7bee22e5281f50724700bdf8d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRISPLD2 LTBP3 FBN1

3.92e-041943332d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN IRS2 PSME4

3.92e-041943333a1f95639d5f239f001bd67d4213e8938e7f299d
DiseaseGeleophysic dysplasia

LTBP3 FBN1

8.67e-065282C3489726
DiseaseAcromicric Dysplasia

LTBP3 FBN1

8.67e-065282C0265287
Diseaseintraocular pressure measurement

RELN LTBP3 FBN1 GPR158 FOLH1

1.06e-04509285EFO_0004695
DiseaseHyperglycemia, Postprandial

IRS2 FBN1

3.72e-0430282C1855520
DiseaseHyperglycemia

IRS2 FBN1

3.72e-0430282C0020456
DiseaseParoxysmal atrial fibrillation

SOX5 NKX2-5 ASAH1

4.31e-04156283C0235480
DiseasePersistent atrial fibrillation

SOX5 NKX2-5 ASAH1

4.31e-04156283C2585653
Diseasefamilial atrial fibrillation

SOX5 NKX2-5 ASAH1

4.31e-04156283C3468561
DiseaseAtrial Fibrillation

SOX5 NKX2-5 ASAH1

4.64e-04160283C0004238
Diseaseheart disease (implicated_via_orthology)

SOX5 FBN1

5.98e-0438282DOID:114 (implicated_via_orthology)
Diseasegrey matter volume measurement

FOXI2 CUBN

8.01e-0444282EFO_0005420

Protein segments in the cluster

PeptideGeneStartEntry
PGPATPAYSYAKTNG

CTTNBP2NL

336

Q9P2B4
GQPYVCYDPKSSPGT

ERV3-1

76

Q14264
TPKFYPEGTGACYGS

ARSH

451

Q5FYA8
LYPDSNYPPFCSGTG

B3GALT1

226

Q9Y5Z6
CRKSTYPPSGPTYRG

ASAH1

31

Q13510
SPPYLECENGSYKPG

GPR158

266

Q5T848
PADYFAPGVKSYPDG

FOLH1

231

Q04609
SSSSVCIPPKYGYLG

BEND2

466

Q8NDZ0
IYSSPKGNGCAGYPK

DUOX2

1346

Q9NRD8
KSYASGPGPAPPYAA

FOXI2

51

Q6ZQN5
PYKNGRPCSECPPSY

CRISPLD2

211

Q9H0B8
SNSPPYVCYVTLPGG

LIX1L

131

Q8IVB5
LLCSPYYSGNPGPES

MPND

386

Q8N594
YYSGNPGPESKISPF

MPND

391

Q8N594
PGYSCTAAYPAGPSP

NKX2-5

266

P52952
GNIGLYCPYSSKGAP

RELN

1976

P78509
LPRSYKAPYTCGGDS

IRS2

806

Q9Y4H2
CPPETYGPQCASKYD

CUBN

201

O60494
PSGYAPAACSPSYGP

HOXB1

81

P14653
NKYSSCPEPIVPGGY

CR2

86

P20023
YFCKCPPGFYTSPDG

FBN1

311

P35555
EYPSPAYPAFACGSG

B3GALNT2

401

Q8NCR0
GGYRCACTPPAEYSP

LTBP3

1056

Q9NS15
VPSTCYPPEGYGTSC

KRTAP12-4

21

P60329
TCKPEYAYGSAGSPP

FKBP4

106

Q02790
TGYTPGTPYKVSCSP

FAM168B

51

A1KXE4
YGVYPLKEASGCPGA

ZNF431

6

Q8TF32
CYYSLASKVEGPPGS

ZAP70

596

P43403
PGVPSTYKGLPCPYA

TMEM269

136

A0A1B0GVZ9
PGPGYYNPSDCTKVP

STPG1

226

Q5TH74
YCSVPGGFDKPPSEY

PSME4

736

Q14997
CSVPGYYPSNKPGVE

PIAS4

221

Q8N2W9
CPSHTGAGYSYSPQP

ULK2

551

Q8IYT8
PPGFSYKAGCSDPYP

SOX5

301

P35711