Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontau-protein kinase activity

PRKAA1 BRSK2 TAOK1

4.63e-0522643GO:0050321
GeneOntologyMolecularFunctiondeaminase binding

HNRNPCL1 HNRNPCL3

6.04e-054642GO:1990827
GeneOntologyMolecularFunctiontau protein binding

PRKAA1 BRSK2 TAOK1

4.32e-0446643GO:0048156
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1 STKLD1

5.48e-04446647GO:0004674
GeneOntologyCellularComponentnucleoplasmic periphery of the nuclear pore complex

HNRNPCL1 HNRNPCL3

1.37e-046642GO:1990826
DomainhnRNP_C

HNRNPCL1 HNRNPCL4

1.56e-046612IPR017347
DomainSki_Sno

DACH2 DACH1

2.18e-047612PF02437
Domain-

DACH2 DACH1

2.18e-0476123.10.260.20
DomainTransform_Ski

DACH2 DACH1

2.18e-047612IPR003380
DomainPkinase

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1 STKLD1

2.35e-04381617PF00069
DomainKinase-like_dom

CDK17 BMPR2 PI4KA PRKAA1 BRSK2 HIPK2 TAOK1 STKLD1

3.64e-04542618IPR011009
DomainDNA-bd_dom_put

DACH2 DACH1

5.66e-0411612IPR009061
DomainPROTEIN_KINASE_ATP

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1 STKLD1

7.18e-04459617PS00107
DomainProt_kinase_dom

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1 STKLD1

1.04e-03489617IPR000719
DomainSer/Thr_kinase_AS

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1

1.07e-03357616IPR008271
DomainPROTEIN_KINASE_DOM

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1 STKLD1

1.09e-03493617PS50011
DomainPROTEIN_KINASE_ST

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1

1.15e-03362616PS00108
DomainC345C

SFRP5 PCOLCE2

1.38e-0317612SM00643
DomainProtein_kinase_ATP_BS

CDK17 BMPR2 PRKAA1 BRSK2 HIPK2 TAOK1

1.45e-03379616IPR017441
DomainNTR

SFRP5 PCOLCE2

1.73e-0319612PF01759
DomainNetrin_module_non-TIMP

SFRP5 PCOLCE2

1.73e-0319612IPR018933
DomainUDPGT

UGT2B15 UGT2B17

2.12e-0321612PF00201
DomainUDPGT

UGT2B15 UGT2B17

2.12e-0321612PS00375
DomainUDP_glucos_trans

UGT2B15 UGT2B17

2.12e-0321612IPR002213
DomainEPHD

KMT2D PHF14

2.32e-0322612PS51805
DomainNTR

SFRP5 PCOLCE2

2.54e-0323612PS50189
DomainNetrin_domain

SFRP5 PCOLCE2

2.54e-0323612IPR001134
DomainTIMP-like_OB-fold

SFRP5 PCOLCE2

3.24e-0326612IPR008993
DomainS_TKc

CDK17 PRKAA1 BRSK2 HIPK2 TAOK1

6.29e-03359615SM00220
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

KMT2D ANAPC1 MECOM ANKRD28 ZFHX3 RB1CC1 DENND4C ZMYM5

1.00e-0641864834709266
Pubmed

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

PRKAA1 BRSK2 TAOK1

2.66e-061564314976552
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

3.33e-06264232660355
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

3.33e-0626421909870
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

3.33e-06264224121496
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

3.33e-0626423117546
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

3.33e-06264224267955
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

3.33e-06264222170718
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

3.33e-0626423105095
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

3.33e-06264217848572
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

3.33e-06264227496708
Pubmed

A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF.

PRKAA1 MITF

3.33e-06264223728343
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

3.33e-06264228228532
Pubmed

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.

UGT2B15 UGT2B17

3.33e-06264215666817
Pubmed

Patient-specific induced pluripotent stem cell properties implicate Ca2+-homeostasis in clinical arrhythmia associated with combined heterozygous RYR2 and SCN10A variants.

SCN10A RYR2

3.33e-06264237122207
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

3.33e-06264217698910
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B17

9.99e-06364219572376
Pubmed

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

UGT2B15 UGT2B17

9.99e-06364226163549
Pubmed

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

UGT2B15 UGT2B17

9.99e-06364220736324
Pubmed

Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.

UGT2B15 UGT2B17

9.99e-06364226385605
Pubmed

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.

UGT2B15 UGT2B17

9.99e-06364228882566
Pubmed

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.

UGT2B15 UGT2B17

9.99e-06364217988216
Pubmed

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.

UGT2B15 UGT2B17

9.99e-06364223223495
Pubmed

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.

UGT2B15 UGT2B17

9.99e-06364218302198
Pubmed

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

UGT2B15 UGT2B17

9.99e-06364230689982
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

TSGA10 SCN10A CCDC168 RYR2 MEX3C

1.50e-0516864530631154
Pubmed

Specification of jaw identity by the Hand2 transcription factor.

POU3F3 ZFHX3 RB1CC1

1.88e-052864327329940
Pubmed

N6-methylation of RNA-bound adenosine regulator HNRNPC promotes vascular endothelial dysfunction in type 2 diabetes mellitus by activating the PSEN1-mediated Notch pathway.

HNRNPCL1 HNRNPCL3

2.00e-05464236681355
Pubmed

The splicing factor hnRNP C regulates expression of co-stimulatory molecules CD80 and CD40 in dendritic cells.

HNRNPCL1 HNRNPCL3

2.00e-05464223831410
Pubmed

hnRNP C is required for postimplantation mouse development but Is dispensable for cell viability.

HNRNPCL1 HNRNPCL3

2.00e-05464210805751
Pubmed

hnRNPC induces isoform shifts in miR-21-5p leading to cancer development.

HNRNPCL1 HNRNPCL3

2.00e-05464235729324
Pubmed

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.

UGT2B15 UGT2B17

2.00e-05464218281521
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT2B15 UGT2B17

2.00e-05464226176234
Pubmed

Heterogeneous nuclear ribonucleoprotein C1 may control miR-30d levels in endometrial exosomes affecting early embryo implantation.

HNRNPCL1 HNRNPCL3

3.32e-05564229846695
Pubmed

Characterization of two nuclear proteins that interact with cytochrome P-450 1A2 mRNA. Regulation of RNA binding and possible role in the expression of the Cyp1a2 gene.

HNRNPCL1 HNRNPCL3

3.32e-0556429128719
Pubmed

Evaluating the role of hnRNP-C and FMRP in the cAMP-induced APP metabolism.

HNRNPCL1 HNRNPCL3

3.32e-05564225809670
Pubmed

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.

HNRNPCL1 MITF PHF14 ZFHX3 LAP3 HNRNPCL3

3.40e-0533264630595499
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GPRASP1 EMC3 PI4KA KIAA1217 DOCK9 RABGAP1L BRSK2 TCF25 ANKRD28 RYR2

4.15e-051139641036417873
Pubmed

Opposite Dysregulation of Fragile-X Mental Retardation Protein and Heteronuclear Ribonucleoprotein C Protein Associates with Enhanced APP Translation in Alzheimer Disease.

HNRNPCL1 HNRNPCL3

4.98e-05664226048669
Pubmed

Mouse Dach2 mutants do not exhibit gross defects in eye development or brain function.

DACH2 DACH1

4.98e-05664216470613
Pubmed

Selective disruption of genes expressed in totipotent embryonal stem cells.

HNRNPCL1 HNRNPCL3

4.98e-0566421317320
Pubmed

LKB1 and AMPK regulate synaptic remodeling in old age.

PRKAA1 BRSK2

4.98e-05664225086610
Pubmed

Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation.

DACH2 HIPK2

4.98e-05664216917507
Pubmed

Protein kinase CK1alpha regulates mRNA binding by heterogeneous nuclear ribonucleoprotein C in response to physiologic levels of hydrogen peroxide.

HNRNPCL1 HNRNPCL3

4.98e-05664215687492
Pubmed

Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.

UGT2B15 UGT2B17

4.98e-05664221365123
Pubmed

Concomitant transitory up-regulation of X-linked inhibitor of apoptosis protein (XIAP) and the heterogeneous nuclear ribonucleoprotein C1-C2 in surviving cells during neuronal apoptosis.

HNRNPCL1 HNRNPCL3

4.98e-05664218363099
Pubmed

TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex.

TXNRD2 ECSIT LAP3 UNC80

5.58e-0511264424344204
Pubmed

Roles of tau protein in health and disease.

PRKAA1 BRSK2 TAOK1

5.59e-054064328386764
Pubmed

Ulk1-mediated phosphorylation of AMPK constitutes a negative regulatory feedback loop.

PRKAA1 RB1CC1

6.96e-05764221460634
Pubmed

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

PRKAA1 RB1CC1

6.96e-05764221258367
Pubmed

Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.

HNRNPCL1 HNRNPCL3

6.96e-05764225846207
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B15 UGT2B17

6.96e-05764226074487
Pubmed

Mouse Dach1 and Dach2 are redundantly required for Müllerian duct development.

DACH2 DACH1

9.27e-05864218395837
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B15 UGT2B17

9.27e-05864232093886
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT2B15 UGT2B17

9.27e-05864222579593
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B15 UGT2B17

9.27e-05864218719240
Pubmed

TACC1-chTOG-Aurora A protein complex in breast cancer.

CDK17 MECOM

9.27e-05864214603251
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B15 UGT2B17

9.27e-05864220142249
Pubmed

Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization.

HNRNPCL1 HNRNPCL3

1.19e-04964210452948
Pubmed

Pleiotropic effects in Eya3 knockout mice.

DACH2 DACH1

1.19e-04964219102749
Pubmed

Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.

PRKAA1 BRSK2

1.49e-041064225728766
Pubmed

Targeted disruption of mouse Dach1 results in postnatal lethality.

DACH2 DACH1

1.49e-041064212508235
Pubmed

Network organization of the human autophagy system.

RABGAP1L PRKAA1 BRSK2 TAOK1 RB1CC1 LAP3

1.54e-0443764620562859
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

PTPRK PI4KA ANKRD28

1.71e-045864331067491
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDK17 BMPR2 PI4KA KIAA1217 RABGAP1L BRSK2 DENND4C MEX3C

1.78e-0486164836931259
Pubmed

MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy.

PRKAA1 RB1CC1

1.81e-041164228059666
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ADAMTS1 ANAPC1 TCF25 MECOM ANKRD28 ZFHX3 BCL7A INO80D UNC80

1.97e-04111664931753913
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B15 UGT2B17

2.17e-041264220308471
Pubmed

Interaction between nucleosome assembly protein 1-like family members.

HNRNPCL1 HNRNPCL3

2.17e-041264221333655
Pubmed

The biogenesis of the coiled body during early mouse development.

HNRNPCL1 HNRNPCL3

2.17e-04126427768196
Pubmed

WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.

PRKAA1 RB1CC1

2.57e-041364228561066
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

ANAPC1 TCF25 ANKRD28 RB1CC1

2.60e-0416764425659891
Pubmed

The DNA sequence and analysis of human chromosome 13.

DOCK9 DACH1 CCDC168 ZMYM5

2.79e-0417064415057823
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

KMT2D PAF1 INO80D

2.86e-046964328481362
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

MITF DACH1 HIPK2 POU3F3 ZFHX3

3.04e-0431864516919269
Pubmed

Huntingtin functions as a scaffold for selective macroautophagy.

PRKAA1 RB1CC1

3.45e-041564225686248
Pubmed

The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer.

DACH1 POU3F3 ZFHX3

3.65e-047564337298722
Pubmed

Six1 controls patterning of the mouse otic vesicle.

DACH2 DACH1

4.45e-041764214695375
Pubmed

A method to identify cDNAs based on localization of green fluorescent protein fusion products.

HNRNPCL1 HNRNPCL3

4.45e-041764210716735
Pubmed

Interaction network of human early embryonic transcription factors.

KMT2D MITF MECOM ZFHX3 BCL7A

4.76e-0435164538297188
Pubmed

Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer-Rokitansky-Küster-Hauser syndrome.

DACH2 DACH1

5.00e-041864236282544
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

HNRNPCL1 DOCK9 TAOK1 RB1CC1 HNRNPCL3

5.55e-0436364514691545
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

BMPR2 PI4KA KIAA1217 DOCK9 RB1CC1 DENND4C

6.04e-0456564625468996
Pubmed

Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms.

PRKAA1 BRSK2

6.20e-042064218227155
Pubmed

The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.

MECOM ZFHX3

6.20e-042064235177643
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

KMT2D EMC3 PTPRK PI4KA PDP2 ANKRD28 RB1CC1 PAF1

6.62e-04104964827880917
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

ADAMTS1 RYR2

6.84e-042164228302382
Pubmed

Mendelian randomization and experimental IUGR reveal the adverse effect of low birth weight on lung structure and function.

BMPR2 PRKAA1

6.84e-042164233372189
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ANAPC1 PI4KA KIAA1217 HIPK2 MECOM PAF1

7.44e-0458864638580884
Pubmed

The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.

BMPR2 RYR2

8.23e-042364226321200
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

KMT2D CELF3

8.23e-04236429225980
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

TBC1D32 TMEM67 BMPR2

8.46e-0410064325807483
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

TBC1D32 KMT2D ANAPC1 PI4KA DACH1 MECOM ANKRD28

9.87e-0485764725609649
Pubmed

Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.

HNRNPCL1 HNRNPCL3

1.05e-032664215890332
Pubmed

Tissue-specific regulation of retinal and pituitary precursor cell proliferation.

DACH2 DACH1

1.05e-032664212130660
Pubmed

La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).

GPRASP1 TCF25 RB1CC1

1.11e-0311064325940091
Pubmed

Dachshund homologues play a conserved role in islet cell development.

DACH2 DACH1

1.14e-032764220869363
Pubmed

Human transcription factor protein interaction networks.

KMT2D MITF DACH1 HIPK2 MECOM ANKRD28 ZFHX3 BCL7A INO80D

1.17e-03142964935140242
Pubmed

Genetic link between renal birth defects and congenital heart disease.

TBC1D32 TMEM67

1.22e-032864227002738
Pubmed

Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.

POU3F3 RYR2

1.22e-032864223006423
InteractionPHF21A interactions

KMT2D ANAPC1 RABGAP1L MECOM ANKRD28 ZFHX3 RB1CC1 DENND4C

1.25e-05343648int:PHF21A
Cytoband4q13

UGT2B15 UGT2B17

1.99e-04156424q13
Cytoband2q12.1

ANAPC1 POU3F3

3.22e-04196422q12.1
GeneFamilyAtaxins|Trinucleotide repeat containing

KMT2D CELF3

1.60e-0325432775
GeneFamilyUDP glucuronosyltransferases

UGT2B15 UGT2B17

2.62e-0332432363
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2D MECOM

2.95e-0334432487
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN

DOCK9 MITF PHF14 ZFHX3 RB1CC1

1.82e-0684635M13008
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

CDK17 ADAMTS1 DOCK9 DACH1 HIPK2 MECOM ZFHX3

1.09e-08190647a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMPR2 DACH2 PTPRK KIAA1217 DOCK9 DACH1 MECOM

1.25e-081946470b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDK17 ADAMTS1 KIAA1217 DOCK9 DACH1 MECOM

2.26e-071796462a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DACH2 SCN10A TCF25 ZFHX3 CTSS RYR2

2.83e-0718664623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PKNOX2 DACH2 HIPK2 MECOM ZFHX3 UNC80

2.92e-0718764613731298bc562ec29582f5da1b4c97261284f6f1
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMPR2 RHBDL2 PTPRK KIAA1217 DOCK9 LAP3

3.31e-07191646a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

BMPR2 ADAMTS1 DOCK9 HIPK2 MECOM INO80D

3.62e-07194646b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

CDK17 BMPR2 KIAA1217 DOCK9 DACH1 INO80D

4.20e-07199646793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP5 ADAMTS1 CELF3 POU3F3 UNC80

6.79e-061846453da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

PTPRK KIAA1217 DOCK9 MECOM TMC5

6.97e-06185645cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PKNOX2 DACH2 MECOM ZFHX3 UNC80

6.97e-061856459f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PKNOX2 HIPK2 MECOM ZFHX3 RYR2

7.16e-061866457def03dd856b765bd3f493288641981c4f7fd26e
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

CDK17 ADAMTS1 DOCK9 DACH1 MECOM

7.35e-0618764540ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

BMPR2 ADAMTS1 DOCK9 DACH1 MECOM

7.35e-0618764581affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

CDK17 BMPR2 DOCK9 HIPK2 MECOM

7.74e-0618964575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

CDK17 BMPR2 DOCK9 HIPK2 MECOM

7.74e-06189645c81787a8c662db5d7814c583dd64562857629e81
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

BMPR2 PTPRK KIAA1217 DOCK9 DACH1

7.94e-06190645812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDK17 ADAMTS1 DOCK9 DACH1 MECOM

7.94e-06190645f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

BMPR2 KIAA1217 DOCK9 DACH1 MECOM

7.94e-061906459fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BMPR2 ADAMTS1 DOCK9 DACH1 MECOM

8.14e-0619164550601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

BMPR2 PTPRK KIAA1217 DOCK9 DACH1

8.14e-06191645c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

BMPR2 PTPRK KIAA1217 DOCK9 DACH1

8.14e-06191645322237793a1278bafb14e63cab688b353e352dcc
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

CDK17 BMPR2 KIAA1217 DOCK9 MECOM

8.14e-06191645c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

PTPRK KIAA1217 DOCK9 MECOM TMC5

8.35e-06192645efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACH2 KIAA1217 DOCK9 DACH1 MECOM

8.56e-06193645e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACH2 KIAA1217 DOCK9 DACH1 MECOM

8.56e-061936456e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACH2 KIAA1217 DOCK9 DACH1 MECOM

8.56e-06193645af5108260783e69a7d67896c5bf64f862525926d
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPRASP1 TCF25 TAOK1 RB1CC1 UNC80

8.78e-061946458aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMPR2 DACH2 KIAA1217 DOCK9 DACH1

8.78e-0619464558f069efdefa0366033764446b9d6ffd4a17807e
ToppCellCTRL-Myeloid-Alveolar_Macrophage|CTRL / Disease state, Lineage and Cell class

MITF HIPK2 PCOLCE2 CTSS DENND4C

8.78e-06194645be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BMPR2 DACH2 KIAA1217 DOCK9 DACH1

8.78e-06194645bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

BMPR2 KIAA1217 DOCK9 DACH1 MECOM

9.00e-06195645fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

BMPR2 KIAA1217 DOCK9 DACH1 MECOM

9.00e-0619564519e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

CDK17 KIAA1217 DOCK9 DACH1 MECOM

9.00e-0619564550a193475db1bb1e05b8590225a553688c372c14
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

BMPR2 PTPRK KIAA1217 DOCK9 DACH1

9.23e-06196645ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

BMPR2 PTPRK KIAA1217 DOCK9 DACH1

9.46e-061976457e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

BMPR2 KIAA1217 DOCK9 DACH1 MECOM

9.46e-06197645ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

BMPR2 KIAA1217 DOCK9 DACH1 MECOM

9.46e-06197645f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellCOVID-19-lung-Capillary_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDK17 BMPR2 DOCK9 DACH1 INO80D

9.69e-0619864545419f2804b4be79bae6632e71c54e1af482d115
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

GPRASP1 RABGAP1L TCF25 TAOK1 UNC80

9.93e-06199645f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

BMPR2 ADAMTS1 DACH1 MECOM LAP3

1.02e-052006452ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

BMPR2 RHBDL2 KIAA1217 DOCK9 LAP3

1.02e-052006456f531a418ff25b59a543800cf4bce7b72404ce08
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

BMPR2 RHBDL2 KIAA1217 DOCK9 LAP3

1.02e-05200645edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

BMPR2 KIAA1217 DOCK9 DACH1 LAP3

1.02e-0520064581e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

BMPR2 KIAA1217 DOCK9 DACH1 MECOM

1.02e-05200645b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

BMPR2 KIAA1217 DOCK9 DACH1 LAP3

1.02e-05200645432384faeade8e609154fab3d96c955a8ec868dd
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

BMPR2 KIAA1217 DOCK9 DACH1 LAP3

1.02e-052006454bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCellremission-multiplets|World / disease stage, cell group and cell class

TBC1D32 SFRP5 DACH1 RHAG

5.22e-05142644286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKNOX2 CELF3 ZFHX3 RYR2

7.51e-051566446365b69ede98bc866e996bc52736b00401aacf6f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DACH1 PCOLCE2 CCDC168 UNC80

8.09e-05159644fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DACH1 PCOLCE2 CCDC168 UNC80

8.09e-05159644aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DACH1 PCOLCE2 CCDC168 UNC80

8.09e-051596448bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

BMPR2 KIAA1217 DOCK9 DACH1

8.29e-05160644958256e3d3836160763b82bb48f794087918d935
ToppCellsevere_influenza-cDC|severe_influenza / disease group, cell group and cell class (v2)

SFRP5 BRSK2 MECOM BCL7A

8.49e-051616447716315b8bda904b346cea47edc2c0b507a345c2
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRK KIAA1217 MECOM TMC5

8.70e-051626445c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellInfluenza_Severe-cDC|World / Disease group and Cell class

SFRP5 IFTAP KCNJ5 MECOM

9.12e-05164644c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

9.34e-05165644fee7f2f8d0e25c0d067adc73f8913721bd709a3e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

9.56e-05166644739dfbe927f409821ff23aca6e47ebe78f57e859
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

9.78e-05167644a6ff7a3d9b80839c0efa91658836812e868561fa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.00e-041686447abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.02e-041696440c341f91dc21aaf92bead18d59684d11510502ce
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.05e-0417064484d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.05e-04170644417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

PKNOX2 ADAMTS1 DACH1 RYR2

1.07e-04171644080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CDK17 TMEM67 DACH1 BCL7A

1.07e-04171644714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDK17 ADAMTS1 DOCK9 DACH1

1.07e-041716441597459c971d6befa991d59dc66b41b6a522f797
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.10e-04172644cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

IFTAP DACH1 MECOM ANKRD28

1.10e-04172644a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

DACH1 MECOM ANKRD28 UNC80

1.12e-0417364434357f0e22c4b6d84582492c82c1ea733ca8477d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK KIAA1217 MECOM TMC5

1.12e-04173644b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.15e-04174644e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

DACH2 CELF3 DACH1 UNC80

1.17e-041756444db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

DACH2 CELF3 DACH1 UNC80

1.17e-041756448d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1217 DACH1 ZFHX3 PCOLCE2

1.20e-04176644ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SLC8A3 MYH7B PCOLCE2 BCL7A

1.25e-04178644c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK KIAA1217 MECOM TMC5

1.28e-04179644cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CDK17 ADAMTS1 DOCK9 MECOM

1.28e-041796441ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

BMPR2 KIAA1217 DOCK9 DACH1

1.33e-04181644c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

PTPRK KIAA1217 MECOM TMC5

1.33e-04181644c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BMPR2 KIAA1217 DOCK9 DACH1

1.36e-04182644a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DACH2 ADAMTS1 HIPK2 RYR2

1.36e-04182644ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KMT2D PI4KA CELF3 UNC80

1.36e-041826441923932a9c60e9ec33db69ded441210d1fb07bec
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KMT2D PI4KA CELF3 UNC80

1.36e-0418264469ff652f74cc47fbe0bd665ab17c445c5b959dad
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK9 DACH1 MECOM LAP3

1.39e-04183644ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1217 DOCK9 DACH1 HIPK2

1.39e-04183644e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell3'_v3-lymph-node_spleen-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

SLC8A3 MAS1L MITF ANKRD28

1.42e-0418464483675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCellwk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DACH2 CELF3 BRSK2 UNC80

1.42e-041846449e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MS4A14 PCOLCE2 CTSS DENND4C

1.42e-04184644840fac463665ed18752f402f7d1ef2e5052bdf74
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cells|lymph-node_spleen / Manually curated celltypes from each tissue

SLC8A3 MAS1L MITF ANKRD28

1.42e-04184644ed266bd2d12f86e8786473e64fbcd58319cd4c2a
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

MYH7B RABGAP1L MITF RYR2

1.42e-04184644ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOPD-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

MITF ANKRD28 PCOLCE2 DENND4C

1.42e-041846447fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

ADAMTS1 DOCK9 DACH1 MECOM

1.42e-041846440f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MECOM ZFHX3 UNC80 RYR2

1.45e-041856447dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

PKNOX2 ADAMTS1 DACH1 RYR2

1.45e-041856444905adaeeffd353e089578e5ea614437dbe794e6
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

MYH7B RABGAP1L MITF RYR2

1.45e-041856446baccb26f999145e51b91d94315bf8d4655bef31
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PKNOX2 HIPK2 MECOM ZFHX3

1.45e-041856441ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS1 DOCK9 DACH1 MECOM

1.45e-04185644a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRK KIAA1217 MECOM TMC5

1.48e-041866442ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

BMPR2 KIAA1217 DOCK9 DACH1

1.48e-04186644c6075fe84226b370c5139066793844ad33ae2db1
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

PTPRK KIAA1217 MECOM TMC5

1.48e-041866449798428691408e17ff2af2fe2d1b345f074d67e4
DrugR(-)-Denopamine

KCNJ5 UGT2B15 UGT2B17 PAF1

2.05e-0633634CID000003818
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

1.22e-053602EFO_0800574
DiseaseX-25937 measurement

UGT2B15 UGT2B17

2.43e-054602EFO_0800937
DiseaseAuriculo-Ventricular Dissociation

KCNJ5 SCN10A

2.43e-054602C0004331
DiseaseHeart Block

KCNJ5 SCN10A

2.43e-054602C0018794
DiseaseX-24574 measurement

UGT2B15 UGT2B17

8.48e-057602EFO_0800897
Diseasefamilial sick sinus syndrome

SCN10A ZFHX3

1.13e-048602MONDO_0012061
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

1.13e-048602EFO_0800575
DiseaseMeckel syndrome (implicated_via_orthology)

TBC1D32 TMEM67

1.13e-048602DOID:0050778 (implicated_via_orthology)
Diseasesick sinus syndrome

SCN10A ZFHX3

1.13e-048602MONDO_0001823
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 40

TAOK1 POU3F3

1.45e-049602C4225275
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

1.81e-0410602EFO_0022090
DiseaseDNA repair protein RAD51 homolog 4 measurement

UGT2B15 UGT2B17

2.21e-0411602EFO_0801531
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

2.65e-0412602EFO_0800291
DiseaseParoxysmal atrial fibrillation

KCNJ5 SCN10A ZFHX3 MEX3C

2.91e-04156604C0235480
Diseasefamilial atrial fibrillation

KCNJ5 SCN10A ZFHX3 MEX3C

2.91e-04156604C3468561
DiseasePersistent atrial fibrillation

KCNJ5 SCN10A ZFHX3 MEX3C

2.91e-04156604C2585653
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

3.13e-0413602EFO_0800293
DiseaseX-19141 measurement

UGT2B15 UGT2B17

3.13e-0413602EFO_0800799
DiseaseAtrial Fibrillation

KCNJ5 SCN10A ZFHX3 MEX3C

3.21e-04160604C0004238
Diseasechromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)

PI4KA TXNRD2

3.64e-0414602DOID:0060413 (implicated_via_orthology)
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

3.64e-0414602EFO_0800283
DiseaseSinus Node Dysfunction (disorder)

KCNJ5 SCN10A

4.20e-0415602C0428908
DiseaseRomano-Ward Syndrome

KCNJ5 SCN10A

4.79e-0416602C0035828
Diseasenon-high density lipoprotein cholesterol measurement

BMPR2 RABGAP1L MITF UGT2B15 UGT2B17 PCOLCE2 DENND4C

5.94e-04713607EFO_0005689
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

6.09e-0418602EFO_0800288
Diseaseetiocholanolone glucuronide measurement

UGT2B15 UGT2B17

6.80e-0419602EFO_0800362
DiseaseMammary Carcinoma, Human

BMPR2 KMT2D SFRP5 ADAMTS1 MECOM RB1CC1

6.84e-04525606C4704874
DiseaseMammary Neoplasms, Human

BMPR2 KMT2D SFRP5 ADAMTS1 MECOM RB1CC1

6.84e-04525606C1257931
DiseaseMammary Neoplasms

BMPR2 KMT2D SFRP5 ADAMTS1 MECOM RB1CC1

6.98e-04527606C1458155
Diseaseandrosterone glucuronide measurement

UGT2B15 UGT2B17

7.55e-0420602EFO_0800317
DiseaseBreast Carcinoma

BMPR2 KMT2D SFRP5 ADAMTS1 MECOM RB1CC1

7.77e-04538606C0678222
Diseasegastric ulcer

PRKAA1 MECOM

8.33e-0421602EFO_0009454
DiseaseX-24947 measurement

UGT2B15 UGT2B17

9.15e-0422602EFO_0800910
Diseaseatrial fibrillation

RHBDL2 KCNJ5 SCN10A ZFHX3 MEX3C

9.48e-04371605EFO_0000275
Diseasebody weight

CDK17 EMC3 DACH2 KIAA1217 RABGAP1L MECOM ZFHX3 BCL7A MEX3C

9.58e-041261609EFO_0004338
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

KMT2D MITF

1.00e-0323602C1708353
Diseaseepiandrosterone sulfate measurement

UGT2B15 UGT2B17

1.18e-0325602EFO_0021120
DiseaseHVA measurement

ADAMTS1 DENND4C

1.28e-0326602EFO_0005131
Diseasecystatin C measurement

BMPR2 KIAA1217 MITF DACH1 CTSS

1.35e-03402605EFO_0004617
DiseaseMalignant neoplasm of breast

SLC8A3 BMPR2 KMT2D SFRP5 ADAMTS1 PRKAA1 MECOM RB1CC1

1.43e-031074608C0006142
Diseaseobsolete_red blood cell distribution width

BMPR2 KIAA1217 RABGAP1L UGT2B15 MECOM TAOK1 PCOLCE2 STKLD1 DENND4C

1.52e-031347609EFO_0005192
DiseaseProstatic Neoplasms

KMT2D PTPRK UGT2B15 UGT2B17 ZFHX3 TXNRD2

1.56e-03616606C0033578
DiseaseMalignant neoplasm of prostate

KMT2D PTPRK UGT2B15 UGT2B17 ZFHX3 TXNRD2

1.56e-03616606C0376358

Protein segments in the cluster

PeptideGeneStartEntry
TMAAVQMQHMAAINA

CELF3

231

Q5SZQ8
MAHFSSEDQAMLQAM

TBC1D32

1

Q96NH3
MMAAENGQTNTVEML

ANKRD28

861

O15084
TMAMSQMNHLSTIAN

DACH1

451

Q9UI36
ASVAMAMNQMNHLNT

DACH2

331

Q96NX9
NGVNQDSHMMASMLS

ADAMTS1

421

Q9UHI8
MAGDSRNAMNQDMEI

KCNJ5

1

P48544
MDKTSMVNMSHANPG

MECOM

451

Q03112
EEDDGMNDMNHEVMS

ANAPC1

1011

Q9H1A4
SANMDLMRADMGGAA

LAP3

296

P28838
SAMETSMMSVQENIH

RB1CC1

1436

Q8TDY2
MASNVTNKMDPHSMN

HNRNPCL1

1

O60812
MAQVNMTTDLEGSDM

HIPK2

476

Q9H2X6
MASNVTNKMDPHSMN

HNRNPCL3

1

B7ZW38
AAQHLSDTTNCMEMM

BRSK2

641

Q8IWQ3
MAMMTHLNEASVLHN

MYH7B

131

A7E2Y1
MSDLNKMMVQDLHSA

PI4KA

1166

P42356
MASNVTNKMDPHSMN

HNRNPCL4

1

P0DMR1
QYMDDCGNIMSMHNV

CDK17

276

Q00537
MISDANTAGNGFMAM

PCOLCE2

126

Q9UKZ9
CDQAGSSDMEADMAM

PHF14

776

O94880
TNETIHMQMSMAVGQ

MAS1L

56

P35410
VKNSDMHLLDMESMG

RABGAP1L

341

Q5R372
DTSGAAALEMMSQAM

PAF1

231

Q8N7H5
SHQTLEHMEGAMESM

PDP2

166

Q9P2J9
MSAHMSGLEIMDEDQ

IFTAP

1

Q86VG3
ASMMEDVGMQDVHFN

DOCK9

1696

Q9BZ29
QGLHSMNMMEAAASE

BMPR2

181

Q13873
SLDSNSSEMAIMMGA

DENND4C

1061

Q5VZ89
SSQDMLFHDMTSQDM

MS4A14

366

Q96JA4
LFHDMTSQDMQSLDM

MS4A14

371

Q96JA4
MAATFSAEMPIMAQH

INO80D

856

Q53TQ3
GMNHLGDMTSEEVMS

CTSS

76

P25774
EQMTGAAMAMPADTN

EMC3

201

Q9P0I2
LTDMESGSSNAMNMN

CCDC168

1966

Q8NDH2
MMDMHDDNSNQSSIA

BCL7A

86

Q4VC05
VDMNEHTMMFTLNGE

RYR2

1166

Q92736
KMVQSDFMQGAMAAS

POU3F3

71

P20264
DFMQGAMAASNGGHM

POU3F3

76

P20264
AMQQAMMAAHDDSLD

PKNOX2

416

Q96KN3
VFAMCMAGAHDQATM

ECSIT

356

Q9BQ95
AMGNTRQEMTHMVNA

PTPRK

786

Q15262
GHADTNMEEMNMNLK

TMEM67

796

Q5HYA8
MHMANQEANTMSRSQ

GPRASP1

226

Q5JY77
MAAVHDLEMESMNLN

RHBDL2

1

Q9NX52
MEHSADGLMEQMCSS

SFRP5

186

Q5T4F7
DDAQGMMAAMLSHAY

MEX3C

191

Q5U5Q3
CNPSMQAEMHMEQSL

KIAA1217

436

Q5T5P2
LDMMEGDHTVMSNSS

TAOK1

381

Q7L7X3
HMNAKIADFGLSNMM

PRKAA1

161

Q13131
MAVSQIDGHMSGQMV

AKAP3

656

O75969
IDGHMSGQMVEHLMN

AKAP3

661

O75969
SMDEHMAGAAAAMFL

UNC80

1601

Q8N2C7
GMNTHSRASCMQMDD

MITF

211

O75030
DMTSCSFMDGTEAMH

STKLD1

226

Q8NE28
VVNTIFMAMEHHGMS

SCN10A

676

Q9Y5Y9
MGASNTSMAMQAAAL

RHAG

351

Q02094
VHNLDDERMEQMSNM

TSGA10

151

Q9BZW7
NMAMATSLMDIGDSF

ZMYM5

21

Q9UJ78
FDQQMSSMVIEHMAS

TXNRD2

256

Q9NNW7
IEMASMEMANSYGHS

TMC5

296

Q6UXY8
GSMISNMSEESANMI

UGT2B15

311

P54855
MLAVRDMMANFHLND

TCF25

646

Q9BQ70
GSMISNMSEESANMI

UGT2B17

311

O75795
KMDSAASDAQFMMSG

ZFHX3

876

Q15911
SMAMVSNQGHMLSGQ

KMT2D

3346

O14686
EMDGKMMNSHFLDGN

SLC8A3

286

P57103