Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II complex binding

SMYD2 DHX9

1.27e-0339272GO:0000993
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

SMYD2 DHX9

1.68e-0345272GO:0043175
GeneOntologyMolecularFunctionserine-type endopeptidase activity

PRSS1 PRSS2 PRSS48

2.10e-03190273GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

PRSS1 PRSS2 PRSS48

2.67e-03207273GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PRSS1 PRSS2 PRSS48

2.86e-03212273GO:0017171
GeneOntologyMolecularFunctionRNA polymerase binding

SMYD2 DHX9

3.47e-0365272GO:0070063
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

SMYD2 DHX9

3.58e-0366272GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

SMYD2 DHX9

3.58e-0366272GO:0001098
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETD9 SMYD2

3.91e-0369272GO:0016278
HumanPhenoPancreatic pseudocyst

PRSS1 PRSS2

2.77e-05592HP:0005206
HumanPhenoPancreatic calcification

PRSS1 PRSS2

9.93e-05992HP:0005213
DomainTRYPSIN_SER

PRSS1 PRSS2 PRSS48

2.60e-0490263IPR033116
DomainTRYPSIN_HIS

PRSS1 PRSS2 PRSS48

3.86e-04103263IPR018114
DomainTRYPSIN_SER

PRSS1 PRSS2 PRSS48

4.20e-04106263PS00135
DomainTRYPSIN_HIS

PRSS1 PRSS2 PRSS48

4.32e-04107263PS00134
DomainPeptidase_S1A

PRSS1 PRSS2 PRSS48

5.07e-04113263IPR001314
DomainTRYPSIN_DOM

PRSS1 PRSS2 PRSS48

5.33e-04115263PS50240
DomainTryp_SPc

PRSS1 PRSS2 PRSS48

5.61e-04117263SM00020
DomainTrypsin

PRSS1 PRSS2 PRSS48

6.18e-04121263PF00089
DomainTrypsin_dom

PRSS1 PRSS2 PRSS48

6.18e-04121263IPR001254
DomainPeptidase_S1_PA

PRSS1 PRSS2 PRSS48

6.49e-04123263IPR009003
DomainSET_dom

SETD9 SMYD2

2.19e-0350262IPR001214
DomainSET

SETD9 SMYD2

2.19e-0350262PS50280
PathwayREACTOME_ALPHA_DEFENSINS

PRSS1 PRSS2

1.15e-0411212MM14569
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_METHYLATION

SETD9 SMYD2

3.56e-0419212M27639
Pubmed

Pancreatitis-Associated PRSS1-PRSS2 Haplotype Alters T-Cell Receptor Beta (TRB) Repertoire More Strongly Than PRSS1 Expression.

PRSS1 PRSS2

5.80e-07227236191639
Pubmed

Hereditary pancreatitis caused by a double gain-of-function trypsinogen mutation.

PRSS1 PRSS2

5.80e-07227218461367
Pubmed

Role of the Common PRSS1-PRSS2 Haplotype in Alcoholic and Non-Alcoholic Chronic Pancreatitis: Meta- and Re-Analyses.

PRSS1 PRSS2

5.80e-07227233202925
Pubmed

Expression of tumor-associated trypsinogens (TAT-1 and TAT-2) in prostate cancer.

PRSS1 PRSS2

5.80e-07227215651064
Pubmed

Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.

PRSS1 PRSS2

5.80e-07227227846138
Pubmed

Immunoreactive anionic and cationic trypsin in human serum.

PRSS1 PRSS2

5.80e-0722722598466
Pubmed

Pre-diagnostic levels of anionic trypsinogen, cationic trypsinogen, and pancreatic secretory trypsin inhibitor in relation to pancreatic cancer risk.

PRSS1 PRSS2

5.80e-07227220484960
Pubmed

Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).

PRSS1 PRSS2

5.80e-07227214695529
Pubmed

Trypsinogen (PRSS1 and PRSS2) gene dosage correlates with pancreatitis risk across genetic and transgenic studies: a systematic review and re-analysis.

PRSS1 PRSS2

5.80e-07227235089416
Pubmed

Trypsinogen copy number mutations in patients with idiopathic chronic pancreatitis.

PRSS1 PRSS2

5.80e-07227218063422
Pubmed

Gene conversion between functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl.

PRSS1 PRSS2

5.80e-07227215776435
Pubmed

Autocrine extra-pancreatic trypsin 3 secretion promotes cell proliferation and survival in esophageal adenocarcinoma.

PRSS1 PRSS2

1.74e-06327224146905
Pubmed

Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.

PRSS1 PRSS2

1.74e-06327211073713
Pubmed

The origin of trypsin: evidence for multiple gene duplications in trypsins.

PRSS1 PRSS2

1.74e-0632729732462
Pubmed

Trypsin-mediated enzymatic degradation of type II collagen in the human vitreous.

PRSS1 PRSS2

1.74e-06327223882137
Pubmed

Association of claudin2 and PRSS1-PRSS2 polymorphisms with idiopathic recurrent acute and chronic pancreatitis: A case-control study from India.

PRSS1 PRSS2

1.74e-06327226110235
Pubmed

Divergent roles of SPINK1 and PRSS2 variants in tropical calcific pancreatitis.

PRSS1 PRSS2

1.74e-06327219077465
Pubmed

CD4-binding regions of human immunodeficiency virus envelope glycoprotein gp120 defined by proteolytic digestion.

PRSS1 PRSS2

1.74e-0632721763044
Pubmed

Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis.

PRSS1 PRSS2

3.48e-06427233515547
Pubmed

Cloning, characterization and nucleotide sequences of two cDNAs encoding human pancreatic trypsinogens.

PRSS1 PRSS2

3.48e-0642723011602
Pubmed

Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study.

PRSS1 PRSS2

3.48e-06427225253127
Pubmed

Lack of molecular-anatomical evidence for GABAergic influence on axon initial segment of cerebellar Purkinje cells by the pinceau formation.

GAD1 BSN

5.80e-06527222764252
Pubmed

PRSS1-Related Hereditary Pancreatitis

PRSS1 PRSS2

5.80e-06527222379635
Pubmed

Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

PRSS1 PRSS2

8.69e-06627223814066
Pubmed

Urinary matrix metalloproteinase -8, -9, -14 and their regulators (TRY-1, TRY-2, TATI) in patients with diabetic nephropathy.

PRSS1 PRSS2

8.69e-06627218428024
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

XRN1 DOCK5 PRSS1 TOMM70 PRSS2 GTF3C1

8.82e-0665027638777146
Pubmed

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.

PRSS1 PRSS2

1.22e-05727223143602
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

GAD1 BSN STAB1

1.53e-056227319367581
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

XRN1 DOCK5 KRT9 DHX9

1.75e-0520227433005030
Pubmed

Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement.

PRSS1 PRSS2

2.08e-05927211160223
Pubmed

Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.

PRSS1 PRSS2

3.18e-051127219096130
Pubmed

Blood pressure and hypertension are associated with 7 loci in the Japanese population.

CNNM2 CYP17A1

4.50e-051327220479155
Pubmed

Pancreatitis Overview

PRSS1 PRSS2

6.06e-051527224624459
Pubmed

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

CNNM2 CYP17A1

6.92e-051627221572416
Pubmed

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

CNNM2 CYP17A1 STAB1

8.29e-0510927323974872
Pubmed

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

CNNM2 CYP17A1

1.09e-042027219915575
Pubmed

Proteomic discovery of MNT as a novel interacting partner of E3 ubiquitin ligase E6AP and a key mediator of myeloid differentiation.

KRT9 GTF3C1

1.59e-042427226506232
Pubmed

Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.

PRSS1 PRSS2

2.66e-043127219690177
Pubmed

Genome-wide association study identifies eight loci associated with blood pressure.

CNNM2 CYP17A1

2.84e-043227219430483
Pubmed

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

TOMM70 PRSS2 KRT9 DHX9

2.90e-0441827432552912
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

PRSS1 KRT9 DHX9

5.09e-0420227324639526
Pubmed

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

CNNM2 CYP17A1

5.63e-044527221378990
Pubmed

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.

CNNM2 CYP17A1

6.40e-044827224262325
Pubmed

A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.

TOMM70 KRT9

7.23e-045127236896912
Cytoband7q34

PRSS1 PRSS2

4.35e-031672727q34
CytobandEnsembl 112 genes in cytogenetic band chr2q31

GAD1 CFAP210

4.92e-03178272chr2q31
CytobandEnsembl 112 genes in cytogenetic band chr7q34

PRSS1 PRSS2

5.31e-03185272chr7q34
CytobandEnsembl 112 genes in cytogenetic band chr10q24

CNNM2 CYP17A1

5.53e-03189272chr10q24
CytobandEnsembl 112 genes in cytogenetic band chr3p21

BSN STAB1

1.48e-02316272chr3p21
GeneFamilyProteases, serine

PRSS1 PRSS2 PRSS48

3.75e-0563193738
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d8.VSVOva, CD8+ CD45.1+, Spleen, avg-3

XRN1 DOCK5 LYST CYP17A1 DENND4C SKAP1

7.55e-06387276GSM538392_500
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 IGSF10 LYST DHX9

3.70e-06176274749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 PRSS2 BSN DENND4C

3.87e-06178274fcbbcc44271515de1969b4732b6441c012693d5f
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 LYST SKAP1 DHX9

4.23e-061822741710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 LYST SKAP1 DHX9

4.23e-06182274e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 CNNM2 SKAP1 SGPP2

4.91e-06189274f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellControl-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

DOCK5 FCRL3 GTF3C1 LYST

5.01e-061902741584c68b58c7f406d9b0e8451beea3e6f8980c56
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LRRIQ1 SKAP1 SGPP2

8.88e-0514427308005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|367C / Donor, Lineage, Cell class and subclass (all cells)

FCRL3 GTF3C1 SKAP1

1.08e-04154273a39877cdf7b441b5c953f744ed30f1d5acf4ea19
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CNNM2 SKAP1

1.21e-0416027355f599df6e3b7a5a505df4b094c834281311d94a
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 CNNM2 SKAP1

1.21e-04160273296e53e1e0786346d38db2d4188b9a1c0430627b
ToppCellIIF-Other-HSPC|IIF / Disease, Lineage and Cell Type

IGSF10 PRSS2 CFAP210

1.28e-041632731e0d38fbed38ac48478868a1480172a1a3f7c1b7
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS1 PRSS2 STAB1

1.30e-041642734307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS1 PRSS2 STAB1

1.30e-041642731d84aa5b925f502ee9c5fa39714490f613a58028
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS2 CYP17A1 SKAP1

1.30e-041642737a51365bad2910c130bd952805f7a1bef51be481
ToppCellmild_COVID-19-Treg|World / disease group, cell group and cell class (v2)

PRSS1 PRSS2 SKAP1

1.38e-0416727369330689b6e353c8ee9ea1b63a5eac6ab38d456f
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNNM2 BSN SKAP1

1.43e-04169273dbf9b1d52b29bf4b60bd23012cc1ea82d344747f
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD1 PRSS1 PRSS2

1.43e-04169273a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 BSN SKAP1

1.45e-0417027371e5e27c3c4e6cc8dc9b063bd51c21c049f54416
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK5 BSN SKAP1

1.45e-04170273255bbbd00d0e17510c5a8c5faa43ed90d887a9de
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 PRSS2 SKAP1

1.45e-04170273aff226a84e397ab58204325aa9d8b396a881986e
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL3 SKAP1 SGPP2

1.45e-041702739a21048b0248a0cae00ec2d71d5056a678495385
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL3 SKAP1 SGPP2

1.45e-04170273aeac9de12efc727313946a77823aba8ab7cdfbfb
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 PRSS2 SKAP1

1.45e-041702736af16e6f276aec6389ece99505ba13c7edc4c4fa
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

FCRL3 GTF3C1 LYST

1.50e-04172273701de463f85aaad3a4b36a0d5fbc416406620089
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 BSN DENND4C

1.55e-04174273f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellwk_15-18-Hematologic_Lymphocytic-NK-Activated_NK|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FCRL3 LYST SKAP1

1.61e-041762736802ed40eb0f91674d4f0120a3d4888c8a2e9612
ToppCellCOPD-Epithelial-Aberrant_Basaloid|COPD / Disease state, Lineage and Cell class

PRSS1 PRSS2 SGPP2

1.61e-0417627311d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCellCOPD-Epithelial-Aberrant_Basaloid|World / Disease state, Lineage and Cell class

PRSS1 PRSS2 SGPP2

1.63e-0417727322b7cda748cf5e665be54ca5bae89f0c130d5e7f
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 KRT9 BSN

1.66e-041782731bddbc083c36657bd6910f7466126ab325e88176
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD1 KRT9 BSN

1.66e-04178273a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCelldroplet-Marrow-BM-1m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BSN SMYD2 SKAP1

1.72e-04180273ff34195bb7325e61fbf823c103c5e6115d8f1248
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

FCRL3 LYST SKAP1

1.74e-041812738906ee8a7a1616dfe8c3b5c73988416641213629
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 LYST DHX9

1.77e-04182273eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 LYST DHX9

1.77e-04182273f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 LYST DHX9

1.83e-041842731154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XRN1 LYST DHX9

1.86e-041852737adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCelldroplet-Marrow-nan-18m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BSN SMYD2 SKAP1

1.86e-04185273de353368f4f6a7a0a66e391d586879876fbe2734
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGSF10 GAD1 PRSS2

1.89e-04186273722da08cd978249a19855fd3ec8ddda780c99d83
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 SKAP1 SGPP2

1.92e-041872737ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellIPF-Epithelial-Aberrant_Basaloid|IPF / Disease state, Lineage and Cell class

PRSS1 PRSS2 SGPP2

1.92e-0418727319d6a404fc3651d98a93e3848e372df51a239c57
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FCRL3 LYST SKAP1

1.95e-041882736686dbba990066568aa7573e70a7db8b4758f457
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

GAD1 SKAP1 SGPP2

1.95e-041882731d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FCRL3 SKAP1 SGPP2

1.95e-0418827372be6fe654f3a5f654d3b9680145bce7ae9b721d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL3 SKAP1 SGPP2

1.95e-041882739db3d3010cb8a1f3ee1cdccaf3cbaac3cf983fc5
ToppCellhuman_hepatoblastoma-NK.T_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

FCRL3 SKAP1 SGPP2

1.95e-0418827371b7599e7e1d63cc0c8518c0501533755951d58f
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

LRRIQ1 SKAP1 SGPP2

1.95e-04188273186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 SKAP1 SGPP2

1.95e-041882733cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

CNNM2 SKAP1 SGPP2

1.95e-04188273df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellIPF-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

EXT1 SKAP1 SGPP2

1.98e-041892737a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS2 CFAP210 LRRIQ1

1.98e-04189273cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCellIPF-Epithelial-Aberrant_Basaloid|World / Disease state, Lineage and Cell class

PRSS1 PRSS2 SGPP2

1.98e-041892738030a353473da34ae92429f2d822171a2e94248f
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

DOCK5 EXT1 LYST

1.98e-041892735c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellFetal_29-31_weeks-Immune-natural_killer_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FCRL3 LYST SKAP1

1.98e-04189273c604da558c9f4055fb36218452463539f2a73223
ToppCellCOVID-19-kidney-NK|kidney / Disease (COVID-19 only), tissue and cell type

FCRL3 LYST SKAP1

2.01e-04190273e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

XRN1 FCRL3 SKAP1

2.01e-04190273d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell10x5'v1-week_14-16-Lymphocytic_T-T_NK-Treg|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FCRL3 SKAP1 SGPP2

2.01e-041902738540f4dee99280109e38b997d9247b176808c51a
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

DOCK5 EXT1 LYST

2.01e-04190273f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GAD1 CNNM2 SKAP1

2.01e-04190273b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

EXT1 SKAP1 SGPP2

2.04e-041912733ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

GAD1 SKAP1 SGPP2

2.04e-04191273fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK5 GAD1 SMYD2

2.04e-04191273011dc22c488369734749e839d65d52fe46b6a1a4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL3 GTF3C1 SKAP1

2.08e-0419227358a7829b411b02b422ef75e2277a868969cc23e8
ToppCellMild/Remission-B_naive-11|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FCRL3 LYST SKAP1

2.08e-04192273c6f325cddce43b72f013b21dfffc9987fd68b6a7
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 GTF3C1 SKAP1

2.08e-041922731922b0350d3375e67c314dbce8074e5cf986f2ef
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 GTF3C1 SKAP1

2.08e-0419227397c197643e59835c6d45dde9e549c9a1b1bb7288
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tregs|lymph-node_spleen / Manually curated celltypes from each tissue

FCRL3 SKAP1 SGPP2

2.08e-0419227304bd6e135733570e877af9460f87379ed0a5c5f8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL3 GTF3C1 SKAP1

2.08e-04192273ce867b6e78c1d8f30dff81bf572a78a897bc7625
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DOCK5 LRRIQ1 SMYD2

2.08e-04192273d43caf42ec744e895137f31ef65a990e250669d2
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 GTF3C1 SKAP1

2.08e-04192273a4d161e3d48bc020e687808b352325ef9d1cc1f3
ToppCellCOPD-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

DOCK5 FCRL3 LYST

2.11e-041932730020249fa71afb500af73700543bb6f349be6b10
ToppCell10x5'-Lung-Myeloid_Monocytic|Lung / Manually curated celltypes from each tissue

DOCK5 LYST STAB1

2.11e-04193273ebe6be10ef5de9e1da988e263106698d3db42fce
ToppCell3'_v3-Lung-Lymphocytic_NK|Lung / Manually curated celltypes from each tissue

FCRL3 GTF3C1 SKAP1

2.11e-04193273a98ee519e0da93ae4a2dcdda1ee8b4138dec131b
ToppCellIIH-CD8-CD8_1|IIH / Condition, Cell_class and T cell subcluster

FCRL3 LYST SKAP1

2.11e-04193273c5a4926003906d6726155f19061b73fb45d9962c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK5 LYST SKAP1

2.11e-04193273778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOCK5 DENND4C SGPP2

2.11e-041932730ef076417ffe2dd1cbc2c3d1e35c7f8522af143b
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 GTF3C1 SKAP1

2.14e-04194273fa72c2f3e6b8bfc2ef126deb219ec6a44809385b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK5 LYST SKAP1

2.14e-0419427364535db0420e53e4d777d2333b5051e63e8a3373
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL3 GTF3C1 SKAP1

2.14e-041942738bfd7c5be518b81b17913139bcb3ebea01f48dd5
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCRL3 LYST SKAP1

2.14e-0419427313c3674d601c8a7355ce869de1af6401938c0037
ToppCellMS-CD8|MS / Condition, Cell_class and T cell subcluster

FCRL3 LYST SKAP1

2.14e-041942738dfeaa213403cedecb1976bfde1bac84f0155999
ToppCellB_cell_maturation-Naive_B_cell|B_cell_maturation / Lineage and Cell class

FCRL3 LYST SKAP1

2.14e-04194273adb6f9aff65276e0db1f8367149998938b8e4fb0
ToppCellhuman_hepatoblastoma-NK.T_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FCRL3 SKAP1 SGPP2

2.14e-04194273997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL3 GTF3C1 SKAP1

2.14e-04194273f0707601883b234ed477c7704ca9a88efaefc3fd
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK5 LYST SKAP1

2.14e-04194273b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 GTF3C1 SKAP1

2.14e-04194273bc7c4efe2a82057fb95582da983e36f413990902
ToppCellMS-CD8-CD8_1|MS / Condition, Cell_class and T cell subcluster

FCRL3 LYST SKAP1

2.14e-041942739c05eb30c4b5c6fc410b83cb8aa8138bd46527c9
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCRL3 GTF3C1 SKAP1

2.14e-04194273b43788e458a80ab93f485f4577370aec448ad95e
ToppCell3'_v3-Lung-Lymphocytic_NK-NK_CD16|Lung / Manually curated celltypes from each tissue

FCRL3 GTF3C1 SKAP1

2.14e-041942733337042eef91a49f621058785723228cf4dfdad4
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FCRL3 LYST SKAP1

2.17e-041952730a72b8446399807ace5b6c72f865bb40dbd9e92d
ToppCell(0)_NK|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FCRL3 GTF3C1 SKAP1

2.20e-04196273e2578a562d9903a33a7c60db229005680af8141c
ToppCell(0)_NK_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FCRL3 GTF3C1 SKAP1

2.20e-041962739b080859130cf156bfa833dc71fd39734cb9a32d
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRSS2 FCRL3 SKAP1

2.20e-04196273bbdc92ec2e95ed7d782df0c72d94f9a9d9439bf0
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP210 LRRIQ1 SGPP2

2.20e-041962736d02d494196e3f857d53eea46d9419690d43beca
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCRL3 GTF3C1 SKAP1

2.20e-041962736beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL3 GTF3C1 SKAP1

2.20e-04196273c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CFAP210 LRRIQ1 SGPP2

2.20e-04196273af4cdc61830685a888a1209826c23bcf54a43084
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

FCRL3 GTF3C1 SKAP1

2.20e-04196273418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

CFAP210 LRRIQ1 SGPP2

2.20e-0419627387d9881cfec461a5d89b688a83749b618c519485
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCRL3 GTF3C1 SKAP1

2.20e-04196273581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL3 GTF3C1 SKAP1

2.24e-041972732abe27f6722fa0dab801bca4cd19e34c1fb4173e
ComputationalNeighborhood of SERPINI2

PRSS1 PRSS2

6.11e-0425162GNF2_SERPINI2
ComputationalNeighborhood of SPINK1

PRSS1 PRSS2

7.13e-0427162GNF2_SPINK1
DrugAC1Q637U

PRSS1 PRSS2 LYST

3.25e-0712273CID000004869
DrugAC1L1ESB

PRSS1 PRSS2 LYST

4.22e-0713273CID000002926
DrugN-allylglycine

PRSS1 PRSS2

4.06e-063272CID000076651
DrugN-phosphopyridoxyl-L-serine

PRSS1 PRSS2

4.06e-063272CID000195946
DrugZ-Arg-OH

PRSS1 PRSS2

4.06e-063272CID000071055
DrugGB-107

PRSS1 PRSS2

4.06e-063272CID000056813
DrugN-acetyl-L-norvaline methyl ester

PRSS1 PRSS2

4.06e-063272CID000150916
DrugYAKR-CK

PRSS1 PRSS2

4.06e-063272CID005487256
Drugp-amidinophenylpyruvate

PRSS1 PRSS2

4.06e-063272CID000444106
Drugschizopeptin 791

PRSS1 PRSS2

4.06e-063272CID000636821
Drugv 1194

PRSS1 PRSS2

4.06e-063272CID000074702
Drugmitorubrinic acid

PRSS1 PRSS2

4.06e-063272CID000379537
Drug2 alpha-bromoacetoxyprogesterone

PRSS1 PRSS2

4.06e-063272CID000135256
DrugLapg-nh2

PRSS1 PRSS2

4.06e-063272CID003082486
DrugMethotrexate-polylysine

PRSS1 PRSS2

4.06e-063272CID000163214
Drugmethyl octanesulfonate

PRSS1 PRSS2

4.06e-063272CID000165858
DrugASA-PE

PRSS1 PRSS2

4.06e-063272CID003037809
Drug3HFGB

PRSS1 PRSS2

4.06e-063272CID000126268
DrugL-TAPA

PRSS1 PRSS2

4.06e-063272CID000193734
Drug4-chlorobenzenediazonium hexafluorophosphate

PRSS1 PRSS2

4.06e-063272CID002723983
Drugmethyl lignocerate

PRSS1 PRSS2

4.06e-063272CID000075546
Drug10-(carboxyethyl)flavin

PRSS1 PRSS2

4.06e-063272CID003082170
DrugZ-Lys-CH2Cl

PRSS1 PRSS2

4.06e-063272CID000127335
Drug2,6-dimethyl-3-pyridinol

PRSS1 PRSS2

4.06e-063272CID000070732
DrugK-13

GAD1 PRSS1 PRSS2

6.54e-0631273CID000469669
DrugAC1NUUB8

PRSS1 PRSS2 LYST

6.54e-0631273CID005493639
DrugAC1LAOUV

PRSS1 PRSS2

8.11e-064272CID000492408
Drug5'-S-propynyl-5'-thioadenosine

PRSS1 PRSS2

8.11e-064272CID000492409
Drugbromomesaconic acid

PRSS1 PRSS2

8.11e-064272CID006449799
Drug4-Amino-3-nitrobenzoic acid

PRSS1 PRSS2

8.11e-064272CID000074115
Drug4-ethylpiperidine

PRSS1 PRSS2

8.11e-064272CID000076704
DrugN-carbobenzoxyglycine vinyl ester

PRSS1 PRSS2

8.11e-064272CID000047309
Drugtorquatone

PRSS1 PRSS2

8.11e-064272CID000256516
DrugAC1Q5JO7

PRSS1 PRSS2

8.11e-064272CID000128324
DrugDsdgk

PRSS1 PRSS2

8.11e-064272CID000130454
DrugmGBSOM

PRSS1 PRSS2

8.11e-064272CID003080804
DrugNSC-13568

PRSS1 PRSS2

8.11e-064272CID000224783
DrugBa-O

PRSS1 PRSS2

8.11e-064272CID000002280
DrugNSC-45351

PRSS1 PRSS2

8.11e-064272CID000018046
Drugxylaric acid

PRSS1 PRSS2

8.11e-064272CID003084064
Drugindomethacin-NHS

PRSS1 PRSS2

8.11e-064272CID000128571
DrugAC1MRIIV

GAD1 PRSS1 PRSS2

1.32e-0539273CID003518584
DrugM 93

PRSS1 PRSS2

1.35e-055272CID006444952
Drug6-amidinoindole

PRSS1 PRSS2

1.35e-055272CID003018291
DrugAg-B

PRSS1 PRSS2

1.35e-055272CID000004286
Drugbeta-Neuroprotectin

PRSS1 PRSS2

1.35e-055272CID005748443
Drug2,6-diphenoxypyridine

PRSS1 PRSS2

1.35e-055272CID000824772
DrugSr 42128

PRSS1 PRSS2

1.35e-055272CID005487043
Drug4-TGPAP

PRSS1 PRSS2

1.35e-055272CID000132086
DrugPTA-Arg

PRSS1 PRSS2

1.35e-055272CID000194378
DrugAC1L3UIZ

PRSS1 PRSS2

1.35e-055272CID000147121
DrugIle-Phe-Lys-CH2Cl

PRSS1 PRSS2

1.35e-055272CID000124393
DrugI 333

PRSS1 PRSS2

1.35e-055272CID000533915
DrugN-(5'-carboxypentyl)-1-deoxynojirimycin

PRSS1 PRSS2

1.35e-055272CID000133177
Drugrho-guanidinobenzoate

PRSS1 PRSS2

1.35e-055272CID005311472
DrugPTA-GPA

PRSS1 PRSS2

1.35e-055272CID000139330
DrugMeebdp

PRSS1 PRSS2

1.35e-055272CID000132560
Drugpropynyl benzoate

PRSS1 PRSS2

1.35e-055272CID000196666
Drug2 up

PRSS1 PRSS2

2.03e-056272CID000193409
DrugN-benzoyltyrosine butylamide

PRSS1 PRSS2

2.03e-056272CID000125261
DrugCirculin A

PRSS1 PRSS2

2.03e-056272CID000065155
DrugN-benzoyl-L-tyrosine thiobenzyl ester

PRSS1 PRSS2

2.03e-056272CID000191444
Drugazidobestatin

PRSS1 PRSS2

2.03e-056272CID000132261
Drug2-azidoatrazine

PRSS1 PRSS2

2.03e-056272CID003032432
Drug4-TAPAP

PRSS1 PRSS2

2.03e-056272CID000133476
DrugAg2SO4

PRSS1 PRSS2

2.03e-056272CID000159275
DrugDb04336

PRSS1 PRSS2

2.03e-056272CID000002014
DrugN,N-dimethylglycylbenzocaine

PRSS1 PRSS2

2.03e-056272CID000188251
DrugIle-val

PRSS1 PRSS2 CYP17A1

2.64e-0549273CID000435949
Drugbz-Ar

PRSS1 PRSS2

2.83e-057272CID000137302
Drugbromobutide

PRSS1 PRSS2

2.83e-057272CID000053079
Drugleupeptins

PRSS1 PRSS2

2.83e-057272CID003033938
DrugArg-OEt

PRSS1 PRSS2

2.83e-057272CID000439495
DrugInhibitor 61

PRSS1 PRSS2

2.83e-057272CID005327349
DrugKki 7

PRSS1 PRSS2

2.83e-057272CID003082667
DrugZ-Glu-Tyr

PRSS1 PRSS2

2.83e-057272CID000096820
DrugKki 8

PRSS1 PRSS2

2.83e-057272CID000064584
DrugGly-Gly-Arg

PRSS1 PRSS2

2.83e-057272CID000133469
DrugCbz-phe-arg-chn2

PRSS1 PRSS2

2.83e-057272CID005492392
DrugO-4-(ethoxybutyl)berbamine

PRSS1 PRSS2

2.83e-057272CID000188375
Drugpentaammineaquocobalt(III) tetrafluoroborate

PRSS1 PRSS2

2.83e-057272CID000412963
DrugTISCH

GAD1 PRSS1 PRSS2

2.98e-0551273CID000125486
Drug3,5-bis-trifluoromethylphenylboronic acid

PRSS1 PRSS2

3.78e-058272CID000156265
DrugAC1MCHYW

PRSS1 PRSS2

3.78e-058272CID002770087
Drugharderoporphyrin

PRSS1 PRSS2

3.78e-058272CID003081462
DrugBoc hydrazine

PRSS1 PRSS2

3.78e-058272CID000070091
DrugHMTi

PRSS1 PRSS2

3.78e-058272CID000195636
DrugO-methyl-L-serine

PRSS1 PRSS2

3.78e-058272CID000088250
DrugAC1NDMP4

PRSS1 PRSS2

3.78e-058272CID004628293
DrugBio-Phe-CH2Cl

PRSS1 PRSS2

3.78e-058272CID000083924
DrugBio-Arg-CH2Cl

PRSS1 PRSS2

3.78e-058272CID000083923
DrugAC1L9R2Z

PRSS1 PRSS2 LYST STAB1

4.40e-05168274CID000453624
DrugPtdIns(3,5)P

PRSS1 PRSS2

4.85e-059272CID000643961
Drug4Amf

PRSS1 PRSS2

4.85e-059272CID000150955
DrugAC1MJ5M1

PRSS1 PRSS2

4.85e-059272CID003086119
Drugp-guanidino-L-phenylalanine

PRSS1 PRSS2

4.85e-059272CID000165028
DrugtlmE

PRSS1 PRSS2

4.85e-059272CID000188322
DrugFK-401

PRSS1 PRSS2

4.85e-059272CID000135041
Drugdansyl-L-arginine

PRSS1 PRSS2

4.85e-059272CID000119895
DrugSurfynol

PRSS1 PRSS2

4.85e-059272CID000061018
DiseaseHereditary pancreatitis

PRSS1 PRSS2

6.88e-065252cv:C0238339
DiseasePANCREATITIS, HEREDITARY

PRSS1 PRSS2

6.88e-065252167800
DiseaseAutosomal Dominant Hereditary Pancreatitis

PRSS1 PRSS2

6.88e-065252C4080064
DiseaseHereditary pancreatitis

PRSS1 PRSS2

1.44e-057252C0238339
DiseasePancreatitis, Chronic

PRSS1 PRSS2

2.47e-059252C0149521
Diseaseepilepsy (implicated_via_orthology)

GAD1 BSN DHX9

3.48e-04163253DOID:1826 (implicated_via_orthology)
Diseaseunipolar depression, systolic blood pressure

CNNM2 CYP17A1

3.80e-0434252EFO_0003761, EFO_0006335
Diseaseanxiety

CNNM2 CYP17A1 STAB1

8.66e-04223253EFO_0005230
Diseasemethadone dose measurement

PRSS1 PRSS2

1.26e-0362252EFO_0007907
DiseaseManic

GAD1 STAB1

1.99e-0378252C0338831
Diseasecoronary artery disease

DOCK5 IGSF10 SETD9 CNNM2 BSN

2.91e-031194255EFO_0001645
Diseasemean fractional anisotropy measurement

DOCK5 KRT9

2.93e-0395252EFO_0008399
Diseasealcoholic pancreatitis

PRSS1 PRSS2

3.12e-0398252EFO_1002013
Diseasecognitive function measurement, self reported educational attainment

GAD1 BSN STAB1

3.26e-03355253EFO_0004784, EFO_0008354
Diseaseendometrial carcinoma

EXT1 SKAP1

4.12e-03113252EFO_1001512
Diseasewhite matter microstructure measurement

DOCK5 KRT9 SGPP2

4.25e-03390253EFO_0005674

Protein segments in the cluster

PeptideGeneStartEntry
KKGPAAIQKNYSPYY

KRT9

191

P35527
GLKKNVYEQQKYYGM

BSN

3411

Q9UPA5
AKQKGYVPFYVNATA

GAD1

331

Q99259
QAKYKAFVAYQKYGP

LRRIQ1

291

Q96JM4
ETPQLYYKYKQVAPK

IGSF10

396

Q6WRI0
PTKRQKYGVAIYNYN

DOCK5

6

Q9H7D0
KNGFKVYVYPQQKGE

EXT1

111

Q16394
NNFFKLQKKYGPIYS

CYP17A1

51

P05093
IKPNAITYGYYNKVV

DENND4C

851

Q5VZ89
YGKPVNDYSKYINKE

LYST

1701

Q99698
KVYYKDGKQLPNSYN

FCRL3

131

Q96P31
YYKDIKQYVFTTQNP

EQTN

61

Q9NQ60
NQYFQKEKIQGEYKY

DHX9

186

Q08211
LKQYLPNIAYSYDKQ

SETD9

256

Q8NE22
APEAYVQKYVVKNYF

SGPP2

71

Q8IWX5
FYNSQGPKYNFQKSK

CFAP210

531

Q0VFZ6
EKNKKAPEYYLYQRN

CNNM2

666

Q9H8M5
IQNQHKYSIKYNPGY

XRN1

901

Q8IZH2
NQFTKYSYKYKDQPQ

STAB1

456

Q9NY15
GNKYFKAGKYEQAIQ

TOMM70

121

O94826
AQKNRPGVYTKVYNY

PRSS2

221

P07478
KSLPGVYTNVIYYQK

PRSS48

246

Q7RTY5
YDQNYAGNKPVKYQL

ZNF765

126

Q7L2R6
AQKNKPGVYTKVYNY

PRSS1

221

P07477
RYIVKNPQAYLNYKV

GTF3C1

1321

Q12789
QYGQKIIKPYSKHYP

SMYD2

361

Q9NRG4
YYYANEKSKQPKGTF

SKAP1

141

Q86WV1