Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.80e-125174GO:0052871
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.26e-117174GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.26e-117174GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.52e-1110174GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.52e-1110174GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.52e-1110174GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.56e-1013174GO:0016713
GeneOntologyMolecularFunctionarachidonate epoxygenase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.78e-0924174GO:0008392
GeneOntologyMolecularFunctionarachidonate monooxygenase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

6.23e-0927174GO:0008391
GeneOntologyMolecularFunctionaromatase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.85e-0835174GO:0070330
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.22e-0840174GO:0016709
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.44e-0849174GO:0016712
GeneOntologyMolecularFunctionarachidonate binding

CYP4F11 CYP4F2 CYP4F12

2.32e-0715173GO:0050544
GeneOntologyMolecularFunctionicosanoid binding

CYP4F11 CYP4F2 CYP4F12

2.85e-0716173GO:0050542
GeneOntologyMolecularFunctionicosatetraenoic acid binding

CYP4F11 CYP4F2 CYP4F12

2.85e-0716173GO:0050543
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

6.82e-072172GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

6.82e-072172GO:0097259
GeneOntologyMolecularFunctionlong-chain fatty acid binding

CYP4F11 CYP4F2 CYP4F12

1.66e-0628173GO:0036041
GeneOntologyMolecularFunctionmonooxygenase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.34e-06115174GO:0004497
GeneOntologyMolecularFunctionheme binding

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.49e-06154174GO:0020037
GeneOntologyMolecularFunctiontetrapyrrole binding

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.60e-06164174GO:0046906
GeneOntologyMolecularFunctioniron ion binding

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.01e-05166174GO:0005506
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.86e-05194174GO:0016705
GeneOntologyMolecularFunctionfatty acid binding

CYP4F11 CYP4F2 CYP4F12

2.59e-0569173GO:0005504
GeneOntologyMolecularFunctionmonocarboxylic acid binding

CYP4F11 CYP4F2 CYP4F12

9.63e-05107173GO:0033293
GeneOntologyMolecularFunctioncarboxylic acid binding

CYP4F11 CYP4F2 CYP4F12

1.02e-03239173GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

CYP4F11 CYP4F2 CYP4F12

1.21e-03254173GO:0043177
GeneOntologyMolecularFunctionoxidoreductase activity

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.43e-03766174GO:0016491
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

CYP4F2 CYP4F3

6.02e-03138172GO:0016614
GeneOntologyMolecularFunctionlipid binding

CYP4F11 ARHGAP9 CYP4F2 CYP4F12

8.45e-03988174GO:0008289
GeneOntologyMolecularFunctiontransition metal ion binding

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.60e-021189174GO:0046914
GeneOntologyBiologicalProcessleukotriene B4 catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.62e-126164GO:0036101
GeneOntologyBiologicalProcessleukotriene B4 metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

8.44e-127164GO:0036102
GeneOntologyBiologicalProcessleukotriene catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.69e-118164GO:0036100
GeneOntologyBiologicalProcessicosanoid catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.94e-1111164GO:1901523
GeneOntologyBiologicalProcesslong-chain fatty acid catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.19e-1012164GO:0042758
GeneOntologyBiologicalProcessmenaquinone catabolic process

CYP4F11 CYP4F2 CYP4F12

3.83e-103163GO:0042361
GeneOntologyBiologicalProcessmenaquinone metabolic process

CYP4F11 CYP4F2 CYP4F12

1.53e-094163GO:0009233
GeneOntologyBiologicalProcessphylloquinone metabolic process

CYP4F11 CYP4F2 CYP4F12

1.53e-094163GO:0042374
GeneOntologyBiologicalProcessphylloquinone catabolic process

CYP4F11 CYP4F2 CYP4F12

1.53e-094163GO:0042376
GeneOntologyBiologicalProcessvitamin K catabolic process

CYP4F11 CYP4F2 CYP4F12

1.53e-094163GO:0042377
GeneOntologyBiologicalProcessfatty acid derivative catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.75e-0922164GO:1901569
GeneOntologyBiologicalProcessprostaglandin catabolic process

CYP4F11 CYP4F2 CYP4F12

7.65e-096163GO:1905344
GeneOntologyBiologicalProcessprostanoid catabolic process

CYP4F11 CYP4F2 CYP4F12

7.65e-096163GO:0062232
GeneOntologyBiologicalProcessleukotriene metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.40e-0841164GO:0006691
GeneOntologyBiologicalProcessvitamin K metabolic process

CYP4F11 CYP4F2 CYP4F12

6.30e-0811163GO:0042373
GeneOntologyBiologicalProcessfat-soluble vitamin catabolic process

CYP4F11 CYP4F2 CYP4F12

8.39e-0812163GO:0042363
GeneOntologyBiologicalProcessomega-hydroxylase P450 pathway

CYP4F11 CYP4F2 CYP4F12

1.39e-0714163GO:0097267
GeneOntologyBiologicalProcessarachidonate metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.91e-0768164GO:0019369
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.54e-0773164GO:1901616
GeneOntologyBiologicalProcessvitamin catabolic process

CYP4F11 CYP4F2 CYP4F12

3.10e-0718163GO:0009111
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.07e-0782164GO:1901568
GeneOntologyBiologicalProcessketone catabolic process

CYP4F11 CYP4F2 CYP4F12

5.05e-0721163GO:0042182
GeneOntologyBiologicalProcessfatty acid catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.64e-06116164GO:0009062
GeneOntologyBiologicalProcesslong-chain fatty acid metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.14e-06124164GO:0001676
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.43e-06128164GO:0033559
GeneOntologyBiologicalProcessicosanoid metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.67e-06142164GO:0006690
GeneOntologyBiologicalProcessmonocarboxylic acid catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.99e-06145164GO:0072329
GeneOntologyBiologicalProcessfat-soluble vitamin metabolic process

CYP4F11 CYP4F2 CYP4F12

7.80e-0651163GO:0006775
GeneOntologyBiologicalProcesslipid catabolic process

LRP1 CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.84e-06382165GO:0016042
GeneOntologyBiologicalProcessvitamin E metabolic process

CYP4F2 CYP4F12

8.45e-066162GO:0042360
GeneOntologyBiologicalProcessolefinic compound metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.41e-06180164GO:0120254
GeneOntologyBiologicalProcessorganic acid catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.75e-05272164GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.75e-05272164GO:0046395
GeneOntologyBiologicalProcessorganic hydroxy compound metabolic process

LRP1 CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.38e-05641165GO:1901615
GeneOntologyBiologicalProcessepoxygenase P450 pathway

CYP4F2 CYP4F12

1.29e-0422162GO:0019373
GeneOntologyBiologicalProcessvitamin metabolic process

CYP4F11 CYP4F2 CYP4F12

1.38e-04133163GO:0006766
GeneOntologyBiologicalProcessregulation of glial cell migration

LRP1 EFEMP1

2.26e-0429162GO:1903975
GeneOntologyBiologicalProcesssmall molecule catabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.56e-04421164GO:0044282
GeneOntologyBiologicalProcessneuron projection morphogenesis

LRP1 DICER1 LIMK1 RNF157 NOTCH3

2.68e-04802165GO:0048812
GeneOntologyBiologicalProcessneuron projection development

LRP1 DICER1 LIMK1 RNF157 NOTCH3 EFEMP1

2.69e-041285166GO:0031175
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

LRP1 DICER1 LIMK1 RNF157 NOTCH3

2.95e-04819165GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

LRP1 DICER1 LIMK1 RNF157 NOTCH3

3.07e-04826165GO:0048858
GeneOntologyBiologicalProcessvery long-chain fatty acid metabolic process

CYP4F2 CYP4F12

3.31e-0435162GO:0000038
GeneOntologyBiologicalProcessfatty acid metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.62e-04461164GO:0006631
GeneOntologyBiologicalProcessneuron projection extension

LRP1 LIMK1 RNF157

5.07e-04207163GO:1990138
GeneOntologyBiologicalProcessneuron development

LRP1 DICER1 LIMK1 RNF157 NOTCH3 EFEMP1

5.43e-041463166GO:0048666
GeneOntologyBiologicalProcesspositive regulation of cell growth

LRP1 LIMK1 RNF157

5.51e-04213163GO:0030307
GeneOntologyBiologicalProcesspositive regulation of developmental growth

LRP1 LIMK1 RNF157

7.60e-04238163GO:0048639
GeneOntologyBiologicalProcesspositive regulation of axon extension

LRP1 LIMK1

8.18e-0455162GO:0045773
GeneOntologyBiologicalProcessketone metabolic process

CYP4F11 CYP4F2 CYP4F12

1.20e-03279163GO:0042180
GeneOntologyBiologicalProcesspositive regulation of miRNA metabolic process

DICER1 NOTCH3

1.44e-0373162GO:2000630
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

LRP1 LIMK1 RNF157

1.47e-03299163GO:0060560
GeneOntologyBiologicalProcessdevelopmental cell growth

LRP1 LIMK1 RNF157

1.50e-03301163GO:0048588
GeneOntologyBiologicalProcesscell morphogenesis

LRP1 DICER1 LIMK1 RNF157 NOTCH3

1.65e-031194165GO:0000902
GeneOntologyBiologicalProcessglial cell migration

LRP1 EFEMP1

1.72e-0380162GO:0008347
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.03e-03731164GO:0032787
GeneOntologyBiologicalProcesscellular catabolic process

LRP1 CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.04e-031253165GO:0044248
GeneOntologyBiologicalProcesspositive regulation of growth

LRP1 LIMK1 RNF157

2.10e-03339163GO:0045927
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 NOTCH3

2.27e-0392162GO:0048844
GeneOntologyBiologicalProcesspositive regulation of neurogenesis

LRP1 DICER1 LIMK1

2.38e-03354163GO:0050769
GeneOntologyBiologicalProcesspositive regulation of lipid transport

LRP1 CYP4F2

2.78e-03102162GO:0032370
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

DICER1 NOTCH3

2.83e-03103162GO:2000628
GeneOntologyBiologicalProcessregulation of axon extension

LRP1 LIMK1

2.89e-03104162GO:0030516
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

LRP1 LIMK1

3.45e-03114162GO:0050772
GeneOntologyBiologicalProcessmiRNA metabolic process

DICER1 NOTCH3

3.76e-03119162GO:0010586
GeneOntologyBiologicalProcesspositive regulation of nervous system development

LRP1 DICER1 LIMK1

3.80e-03418163GO:0051962
GeneOntologyBiologicalProcessregulation of developmental growth

LRP1 LIMK1 RNF157

3.88e-03421163GO:0048638
GeneOntologyBiologicalProcessregulation of extent of cell growth

LRP1 LIMK1

3.94e-03122162GO:0061387
GeneOntologyBiologicalProcessgliogenesis

LRP1 DICER1 EFEMP1

4.25e-03435163GO:0042063
GeneOntologyBiologicalProcesspositive regulation of lipid localization

LRP1 CYP4F2

4.40e-03129162GO:1905954
GeneOntologyBiologicalProcessregulation of body fluid levels

CYP4F11 CYP4F2 CYP4F12

4.45e-03442163GO:0050878
GeneOntologyCellularComponentapical part of cell

LRP1 CYP4F11 CYP4F2 CYP4F12 CYP4F3

6.04e-05592165GO:0045177
GeneOntologyCellularComponentapical plasma membrane

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.24e-04487164GO:0016324
GeneOntologyCellularComponentaxonal growth cone

LRP1 LIMK1

5.33e-0445162GO:0044295
GeneOntologyCellularComponentgrowth cone

LRP1 DICER1 LIMK1

7.96e-04245163GO:0030426
GeneOntologyCellularComponentsite of polarized growth

LRP1 DICER1 LIMK1

8.73e-04253163GO:0030427
GeneOntologyCellularComponentendoplasmic reticulum membrane

CYP4F11 CYP4F2 CYP4F12 CYP4F3 NOTCH3

2.21e-031293165GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CYP4F11 CYP4F2 CYP4F12 CYP4F3 NOTCH3

2.25e-031299165GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

CYP4F11 CYP4F2 CYP4F12 CYP4F3 NOTCH3

2.48e-031327165GO:0042175
GeneOntologyCellularComponentdistal axon

LRP1 DICER1 LIMK1

4.10e-03435163GO:0150034
HumanPhenoSubretinal fluid

ZNF408 EFEMP1

7.25e-051072HP:0031526
HumanPhenoPeriauricular skin pits

LRP1 ZNF462 DICER1

7.33e-056773HP:0100277
HumanPhenoBranchial anomaly

LRP1 ZNF462 DICER1

1.16e-047873HP:0009794
HumanPhenoSkin pit

LRP1 ZNF462 DICER1

1.44e-048473HP:0100276
HumanPhenoLocalized skin lesion

LRP1 ZNF462 DICER1 LIMK1 NOTCH3 EFEMP1

1.75e-0489776HP:0011355
HumanPhenoNarrow face

LIMK1 NOTCH3 EFEMP1

3.05e-0410873HP:0000275
HumanPhenoBicuspid aortic valve

ZNF462 LIMK1 NOTCH3

4.06e-0411973HP:0001647
HumanPhenoInguinal hernia

DICER1 LIMK1 NOTCH3 EFEMP1

4.17e-0431274HP:0000023
HumanPhenoAbnormal aortic valve cusp morphology

ZNF462 LIMK1 NOTCH3

4.27e-0412173HP:0031567
HumanPhenoDural ectasia

NOTCH3 EFEMP1

4.40e-042472HP:0100775
HumanPhenoPectus excavatum

DICER1 LIMK1 NOTCH3 EFEMP1

4.77e-0432374HP:0000767
HumanPhenoAbnormal spinal meningeal morphology

NOTCH3 EFEMP1

4.78e-042572HP:0010303
HumanPhenoAbnormal periauricular region morphology

LRP1 ZNF462 DICER1

5.39e-0413173HP:0000383
HumanPhenoNuclear cataract

ZNF408 EFEMP1

6.02e-042872HP:0100018
HumanPhenoAbnormal testis morphology

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

6.66e-04112976HP:0000035
HumanPhenoNon-obstructive azoospermia

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

6.76e-04113276HP:0011961
HumanPhenoSmall face

LIMK1 NOTCH3 EFEMP1

6.84e-0414273HP:0000274
HumanPhenoAbnormal rectum morphology

DICER1 LIMK1 EFEMP1

7.27e-0414573HP:0002034
HumanPhenoAzoospermia

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

7.67e-04115776HP:0000027
HumanPhenoColonic diverticula

LIMK1 EFEMP1

7.87e-043272HP:0002253
HumanPhenoAbnormal midface morphology

LRP1 ZNF462 DICER1 LIMK1 NOTCH3

8.20e-0470475HP:0000309
HumanPhenoPulmonary cyst

DICER1 EFEMP1

8.89e-043472HP:0032445
HumanPhenoAbnormal spermatogenesis

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

9.02e-04119076HP:0008669
HumanPhenoAbnormality of the forehead

LRP1 ZNF462 DICER1 LIMK1 NOTCH3 EFEMP1

9.83e-04120876HP:0000290
HumanPhenoBladder diverticulum

LIMK1 EFEMP1

9.97e-043672HP:0000015
HumanPhenoBowel diverticulosis

LIMK1 EFEMP1

1.05e-033772HP:0005222
HumanPhenoSoft tissue sarcoma

LRP1 DICER1 NOTCH3

1.08e-0316673HP:0030448
HumanPhenoAbnormal sacrum morphology

DICER1 LIMK1 NOTCH3

1.10e-0316773HP:0005107
HumanPhenoAbnormal male internal genitalia morphology

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

1.16e-03124376HP:0000022
HumanPhenoAbnormal neck morphology

LRP1 ZNF462 DICER1 LIMK1 NOTCH3

1.22e-0376675HP:0025668
HumanPhenoFunctional abnormality of male internal genitalia

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

1.31e-03126976HP:0000025
HumanPhenoChorioretinal atrophy

ZNF408 EFEMP1

1.49e-034472HP:0000533
HumanPhenoAbnormal male reproductive system physiology

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

1.59e-03131476HP:0012874
HumanPhenoAbnormal male external genitalia morphology

ZNF462 DICER1 LIMK1 ZNF408 NOTCH3 EFEMP1

1.70e-03132976HP:0000032
HumanPhenoNeoplasm of the nervous system

LRP1 DICER1 NOTCH3

1.73e-0319573HP:0004375
HumanPhenoAbnormality of the outer ear

LRP1 ZNF462 DICER1 LIMK1 NOTCH3 EFEMP1

1.76e-03133776HP:0000356
MousePhenoabnormal eye vasculature morphology

CYP4F11 CYP4F2 CYP4F12 NOTCH3 EFEMP1

1.50e-05415125MP:0031346
MousePhenoabnormal retina blood vessel morphology

CYP4F11 CYP4F2 CYP4F12 NOTCH3

3.41e-05234124MP:0010097
MousePhenoabnormal enzyme/coenzyme level

LRP1 CYP4F11 DICER1 CYP4F2 CYP4F12 RNF157 MGRN1

6.33e-051451127MP:0005319
MousePhenoabnormal blood vessel morphology

CYP4F11 DICER1 CYP4F2 CYP4F12 NOTCH3 EFEMP1 MGRN1

6.95e-051472127MP:0001614
MousePhenoabnormal feces composition

CYP4F11 CYP4F2 CYP4F12

7.02e-0598123MP:0003868
MousePhenoherniated abdominal wall

LRP1 EFEMP1

1.27e-0420122MP:0000757
MousePhenoabnormal lens morphology

LRP1 CYP4F11 CYP4F2 CYP4F12 RNF157

1.82e-04699125MP:0001303
MousePhenoabnormal spleen weight

DICER1 NOTCH3 EFEMP1 MGRN1

1.84e-04361124MP:0004951
MousePhenoabnormal retina vasculature morphology

CYP4F11 CYP4F2 CYP4F12 NOTCH3

2.47e-04390124MP:0002792
MousePhenoabnormal retina morphology

CYP4F11 DICER1 CYP4F2 CYP4F12 NOTCH3 EFEMP1

2.62e-041227126MP:0001325
MousePhenoabnormal ocular fundus morphology

CYP4F11 DICER1 CYP4F2 CYP4F12 NOTCH3 EFEMP1

3.07e-041262126MP:0002864
MousePhenoliver degeneration

LRP1 EFEMP1

3.10e-0431122MP:0003103
MousePhenocataract

CYP4F11 CYP4F2 CYP4F12 RNF157

6.22e-04497124MP:0001304
MousePhenopersistence of hyaloid vascular system

CYP4F11 CYP4F2 CYP4F12

7.92e-04223123MP:0001289
MousePhenobrain lesion

NOTCH3 MGRN1

8.09e-0450122MP:0021002
MousePhenoabnormal anterior eye segment morphology

LRP1 CYP4F11 CYP4F2 CYP4F12 RNF157

1.59e-031117125MP:0005193
MousePhenoabnormal enzyme/coenzyme activity

CYP4F11 CYP4F2 CYP4F12

1.64e-03287123MP:0005584
DomainCyt_P450_E_grp-I

CYP4F11 CYP4F2 CYP4F12 CYP4F3

5.24e-0845164IPR002401
DomainCyt_P450_CS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.03e-0753164IPR017972
DomainCYTOCHROME_P450

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.38e-0757164PS00086
Domain-

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.48e-07581641.10.630.10
Domainp450

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.48e-0758164PF00067
DomainCyt_P450

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.70e-0760164IPR001128
DomainEGF_CA

LRP1 NOTCH3 EFEMP1

5.05e-0586163PF07645
DomainEGF_Ca-bd_CS

LRP1 NOTCH3 EFEMP1

7.24e-0597163IPR018097
DomainEGF_CA

LRP1 NOTCH3 EFEMP1

7.69e-0599163PS01187
DomainASX_HYDROXYL

LRP1 NOTCH3 EFEMP1

7.93e-05100163PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 NOTCH3 EFEMP1

9.43e-05106163IPR000152
DomainEGF_CA

LRP1 NOTCH3 EFEMP1

1.43e-04122163SM00179
DomainEGF-like_Ca-bd_dom

LRP1 NOTCH3 EFEMP1

1.50e-04124163IPR001881
DomaincEGF

LRP1 EFEMP1

2.21e-0426162PF12662
DomaincEGF

LRP1 EFEMP1

2.21e-0426162IPR026823
DomainGrowth_fac_rcpt_

LRP1 NOTCH3 EFEMP1

2.96e-04156163IPR009030
DomainEGF

LRP1 NOTCH3 EFEMP1

9.76e-04235163SM00181
DomainEGF_3

LRP1 NOTCH3 EFEMP1

9.76e-04235163PS50026
DomainEGF-like_dom

LRP1 NOTCH3 EFEMP1

1.15e-03249163IPR000742
DomainEGF_1

LRP1 NOTCH3 EFEMP1

1.23e-03255163PS00022
DomainEGF-like_CS

LRP1 NOTCH3 EFEMP1

1.32e-03261163IPR013032
DomainEGF_2

LRP1 NOTCH3 EFEMP1

1.38e-03265163PS01186
DomainEGF

LRP1 NOTCH3

5.09e-03126162PF00008
Domainzf-C3HC4

RNF157 MGRN1

1.53e-02223162PF00097
PathwayREACTOME_EICOSANOIDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.48e-1012124MM14845
PathwayREACTOME_EICOSANOIDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.48e-1012124M27129
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.00e-1014124MM15842
PathwayREACTOME_FATTY_ACIDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.09e-1015124M27126
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.15e-1018124MM14843
PathwayREACTOME_FATTY_ACIDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.15e-1018124MM14841
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.77e-0925124MM14858
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.22e-0833124MM15963
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.22e-0833124MM15918
PathwayREACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

CYP4F11 CYP4F2 CYP4F12

7.75e-0811123MM14863
PathwayREACTOME_MISCELLANEOUS_SUBSTRATES

CYP4F11 CYP4F2 CYP4F3

1.03e-0712123M27128
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.53e-0761124MM14861
PathwayWP_OXIDATION_BY_CYTOCHROME_P450

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.64e-0762124M39653
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.86e-0764124M5650
PathwayREACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.11e-0766124MM14839
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4F11 CYP4F2 CYP4F3

6.21e-0721123M27137
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.32e-06104124M738
PathwayREACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.37e-06105124MM14842
PathwayWP_TRYPTOPHAN_METABOLISM

CYP4F11 CYP4F2 CYP4F12

7.98e-0648123MM15902
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.37e-06170124MM15573
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.25e-05183124M39588
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4F11 CYP4F2 CYP4F3

1.49e-0559123M27140
PathwayWP_EICOSANOID_METABOLISM_VIA_CYTOCHROME_P450_MONOOXYGENASES_PATHWAY

CYP4F2 CYP4F12

2.38e-059122M39819
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.54e-05219124MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.59e-05220124M10320
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOOXYGENASES_LOX

CYP4F2 CYP4F12

2.66e-0429122M39858
PathwayWP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX

CYP4F2 CYP4F12

3.05e-0431122M39851
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4F11 CYP4F2 CYP4F3

3.87e-04176123M27854
PathwayKEGG_ARACHIDONIC_ACID_METABOLISM

CYP4F2 CYP4F3

1.07e-0358122M5410
PathwayREACTOME_METABOLISM_OF_LIPIDS

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.38e-03620124MM15193
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F11 CYP4F2 CYP4F12 CYP4F3

5.02e-14418418065749
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.53e-1361849068972
Pubmed

Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.

CYP4F11 CYP4F2 CYP4F12

4.65e-10418322665481
Pubmed

Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

CYP4F11 CYP4F2 CYP4F12

4.65e-10418311185557
Pubmed

Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.

CYP4F11 CYP4F2 CYP4F12

1.16e-09518322969154
Pubmed

Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.

CYP4F11 CYP4F2 CYP4F12

1.16e-09518321466787
Pubmed

Role of ω-hydroxylase in adenosine-mediated aortic response through MAP kinase using A2A-receptor knockout mice.

CYP4F11 CYP4F2 CYP4F12

4.07e-09718322160543
Pubmed

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.51e-087018415128046
Pubmed

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

CYP4F11 CYP4F2

2.53e-07218224138531
Pubmed

Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.

CYP4F2 CYP4F12

2.53e-07218218662666
Pubmed

Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids.

CYP4F11 CYP4F3

2.53e-07218215364545
Pubmed

Expression and physiological function of CYP4F subfamily in human eosinophils.

CYP4F12 CYP4F3

2.53e-07218217980168
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

2.53e-0721828026587
Pubmed

Low density lipoprotein receptor-related protein-1 (LRP1) regulates thrombospondin-2 (TSP2) enhancement of Notch3 signaling.

LRP1 NOTCH3

7.59e-07318220472562
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

7.59e-07318215145985
Pubmed

Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.

CYP4F11 CYP4F2 CYP4F12

1.52e-064418312745259
Pubmed

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

CYP4F11 CYP4F2 CYP4F12

1.74e-064618325209997
Pubmed

Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157.

RNF157 MGRN1

2.53e-06518225342469
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

2.53e-06518218577768
Pubmed

A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.

RNF157 MGRN1

2.53e-06518232966817
Pubmed

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.

CYP4F11 CYP4F2 CYP4F12

7.99e-067618322323595
Pubmed

Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.

ZNF462 EFEMP1

1.67e-043718219266077
Pubmed

Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination.

DICER1 NOTCH3

1.76e-043818220805985
Pubmed

High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population.

ZNF462 MGRN1

3.83e-045618219591821
Pubmed

The DNA sequence and biology of human chromosome 19.

CYP4F11 CYP4F2 NOTCH3

4.01e-0428418315057824
InteractionATRN interactions

ZNF408 RNF157 MGRN1

1.52e-0555183int:ATRN
InteractionLTBP1 interactions

ZNF408 NOTCH3 EFEMP1

7.15e-0592183int:LTBP1
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CYP4F11 CYP4F2 CYP4F12 CYP4F3 NOTCH3

1.11e-05797185chr19p13
Cytoband19p13.1

CYP4F11 CYP4F12

1.62e-044818219p13.1
Cytoband12q13.3

LRP1 ARHGAP9

1.83e-045118212q13.3
Cytoband8p23.1

PRR23D1 PRR23D2

1.65e-031541828p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

PRR23D1 PRR23D2

3.75e-03234182chr8p23
CytobandEnsembl 112 genes in cytogenetic band chr12q13

LRP1 ARHGAP9

1.18e-02423182chr12q13
GeneFamilyCytochrome P450 family 4

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.31e-08361441003
GeneFamilyRing finger proteins

RNF157 MGRN1

1.86e-0227514258
CoexpressionSAENZ_DETOX_PATHWAY_AND_CARCINOGENESIS_DN

CYP4F11 CYP4F2 CYP4F12

2.11e-0720163MM1104
CoexpressionWOO_LIVER_CANCER_RECURRENCE_DN

CYP4F2 CYP4F12 CYP4F3

1.38e-0578163M9911
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN

LRP1 CYP4F12 CYP4F3 EFEMP1

1.93e-05274164M289
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4

CYP4F11 CYP4F2 CYP4F12 EFEMP1

3.98e-05330164MM1120
CoexpressionCTIP_DN.V1_DN

PI15 CYP4F12 CYP4F3

6.97e-05134163M2751
CoexpressionWANG_TNF_TARGETS

LIMK1 NOTCH3

1.13e-0426162M2308
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

DICER1 NOTCH3

1.22e-0427162MM1135
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

DICER1 NOTCH3

1.22e-0427162M1391
CoexpressionGSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_UP

LIMK1 RNF157 MGRN1

1.36e-04168163M8665
CoexpressionBOCHKIS_FOXA2_TARGETS

LRP1 CYP4F11 CYP4F2 CYP4F12

1.53e-04467164MM1233
CoexpressionNFE2L2.V2

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.55e-04469164M2870
CoexpressionCHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN

CYP4F11 CYP4F2 CYP4F3

1.64e-04179163M16932
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_DN

CYP4F11 CYP4F2 CYP4F12

1.96e-04190163MM1311
CoexpressionGSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP

ARHGAP9 CYP4F2 CYP4F3

2.15e-04196163M5349
CoexpressionGSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP

ARHGAP9 CYP4F2 CYP4F3

2.18e-04197163M5351
CoexpressionGSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_UP

PI15 LIMK1 ZNF408

2.18e-04197163M4993
CoexpressionGSE13522_CTRL_VS_T_CRUZI_BRAZIL_STRAIN_INF_SKIN_DN

LRP1 RNF157 MGRN1

2.24e-04199163M2921
CoexpressionGSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

LRP1 RNF157 NOTCH3

2.28e-04200163M6193
CoexpressionZENG_GU_POST_ICB_METAGENE_39

CYP4F11 CYP4F2 CYP4F12

2.41e-04204163MM17090
CoexpressionPARENT_MTOR_SIGNALING_UP

LRP1 CYP4F11 CYP4F2 CYP4F12

3.21e-04567164M16909
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

LRP1 CYP4F2 CYP4F12

4.86e-04259163M40029
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 ZNF462 NOTCH3 EFEMP1

1.04e-06197184b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 ZNF462 NOTCH3 EFEMP1

1.04e-061971845afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 ZNF462 NOTCH3 EFEMP1

1.04e-061971841baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRR23D1 PRR23D2 CCDC168

3.21e-05156183bcc862d2eb018680fec7e7196704eb285361501f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 PI15 EFEMP1

4.00e-051681834b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 PI15 EFEMP1

4.22e-051711835d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CYP4F11 CYP4F12 EFEMP1

4.45e-0517418353c2c132566a7682f3268c7f9138700f09c3b94d
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

4.45e-05174183cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

5.33e-05185183eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

5.33e-05185183f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 NOTCH3

5.33e-0518518338486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

5.33e-05185183ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 NOTCH3

5.33e-051851833c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 NOTCH3 EFEMP1

5.86e-051911831efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCelldroplet-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 PI15 EFEMP1

5.96e-05192183086b47f87283cd41139cd56686011f8b5821b0da
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PI15 CYP4F11 NOTCH3

5.96e-05192183fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF462 PI15 EFEMP1

6.05e-0519318364edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCelldroplet-Heart-nan-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

6.14e-0519418320a0439fa02c5f8107612e34c7ab54120b9b8573
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 PI15 EFEMP1

6.14e-051941837b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

6.24e-051951839ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP4F11 CYP4F3 NOTCH3

6.24e-0519518324d226f89dd337c22728688e4b40ca082a0e1fe1
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

6.24e-05195183613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCelldroplet-Heart-HEART-1m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 NOTCH3

6.33e-051961831eb14182ef26e6141f510d397b00bf8a12efda3e
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

6.33e-051961836bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PI15 EFEMP1

6.33e-05196183c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellPND28-Mesenchymal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 PI15 NOTCH3

6.33e-05196183119265efd2219f328d8152dbee52af8327aec89c
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 NOTCH3 EFEMP1

6.52e-05198183a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 NOTCH3 EFEMP1

6.52e-051981838b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCell10x3'2.3-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 NOTCH3 EFEMP1

6.52e-051981834739b2e4ab141c66772e61686b45614a1839483e
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 PI15 EFEMP1

6.62e-0519918395d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 NOTCH3 EFEMP1

6.62e-051991839b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 NOTCH3 EFEMP1

6.62e-05199183251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PI15 NOTCH3 EFEMP1

6.62e-05199183117f4f43b6c06dda553799b1063e827bce697370
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 PI15 EFEMP1

6.72e-05200183747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP4F12 CYP4F3 NOTCH3

6.72e-05200183ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

LRP1 NOTCH3 EFEMP1

6.72e-05200183bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

LRP1 PI15 EFEMP1

6.72e-05200183de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Esophagus_Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CYP4F11 CYP4F3

6.33e-04931824ab8c28f7c47129ac633bcfdc7ccc8f7793464d5
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CYP4F2 CYP4F3

8.52e-04108182c647f6595e7cccea91429a2377c9de6cc1acff4d
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PI15 NOTCH3

1.05e-03120182a320799ab5f2ce872e038b15841a23174c5436e8
ToppCellControl-Neutrophil|Control / Disease condition and Cell class

CYP4F2 CYP4F3

1.16e-03126182450c01d89714feee6529680ec3ce69067a54b37c
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP4F2 CYP4F3

1.16e-03126182730fc6dc740613b55e40e85334fa30330aa81c3b
ToppCellControl-Neutrophil-|Control / Disease condition and Cell class

CYP4F2 CYP4F3

1.16e-0312618265fff5ec2296272e94f44546606587833191dd82
ToppCellControl-Myeloid_G-Neutrophil|Control / Disease group, lineage and cell class

CYP4F2 CYP4F3

1.17e-03127182d4af23d621b546785a077c367c3a66c59749fc15
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP4F2 CYP4F3

1.21e-031291825578a9ef85706ab6a204ff31716e781ec3893b75
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

LRP1 EFEMP1

1.21e-0312918213cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellPBMC-Control-Myeloid-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP4F2 CYP4F3

1.23e-03130182124f76067a2d4448ce06158a769d0d11b0297110
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP4F2 CYP4F3

1.23e-03130182cd6d8d646345b01ff0f04f776330a05b82e63bc9
ToppCellControl-Myeloid_G|Control / Disease group, lineage and cell class

CYP4F2 CYP4F3

1.25e-03131182d5a53431f1f1b283fb9338b8561e6381f0227c62
ToppCellPBMC-Mild-Myeloid-Neutrophil-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CYP4F2 CYP4F3

1.31e-031341827b237690a3765d974f6f813ef2d01154bc23b9d6
ToppCellCOVID-19_Mild-Myeloid_G-Neutrophil|COVID-19_Mild / Disease group, lineage and cell class

CYP4F2 CYP4F3

1.32e-03135182e9eb2bebb6d19c439c83f46c12ca0d676db69de8
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

CCDC168 NOTCH3

1.36e-031371829324b55eac55e0cc1e8e450a4b5374d12e9587a3
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Kcnj8_(Mural.Acta2Rgs5.Kcnj8)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CCDC168 NOTCH3

1.36e-03137182032f8409d0d179e254c8ff632afbda78852a9889
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Acta2Rgs5.Kcnj8_(Mural.Acta2Rgs5.Kcnj8)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

CCDC168 NOTCH3

1.36e-03137182265a4a50e48b13c8b3b0730f818235f71fbd6baa
ToppCellClub_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CYP4F3 NOTCH3

1.38e-03138182133015953fc660d00339f47b415da5e9872313a2
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP4F2 CYP4F3

1.46e-03142182191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellCOVID-19_Mild-Myeloid_G|COVID-19_Mild / Disease group, lineage and cell class

CYP4F2 CYP4F3

1.46e-03142182c8aeb747ed836197265d269aa131fae172b45aec
ToppCellPBMC-Mild-Myeloid-Neutrophil|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP4F2 CYP4F3

1.48e-03143182974260c25dad599eea83a33e83117f7307b92a42
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CYP4F2 CYP4F3

1.48e-03143182b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DICER1 CYP4F3

1.51e-03144182b638398f559e7fd9d4294d1c830beeb20f905960
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CCDC168

1.53e-0314518207acbf086cffce0628accf078d31bf190f803988
ToppCelldroplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP9 EFEMP1

1.61e-03149182defe2e4a2f3118f8b42e99a4f2bf03e54c1b698f
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP9 CYP4F3

1.65e-03151182b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PI15 NOTCH3

1.67e-031521820cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

NOTCH3 EFEMP1

1.67e-031521823a1414ba6a4972698c3262a00b124428835c35cb
ToppCell368C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

NOTCH3 EFEMP1

1.67e-03152182ee7855d76a49d07a032677a4dc83aa6116d50518
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PI15 NOTCH3

1.67e-03152182ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCell367C-Fibroblasts-Fibroblast-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

LRP1 EFEMP1

1.72e-03154182dd3d34f065820e706515a13619f19a5b12734c8e
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4F2 CYP4F3

1.72e-0315418289a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCell367C-Fibroblasts-Fibroblast-D|367C / Donor, Lineage, Cell class and subclass (all cells)

LRP1 EFEMP1

1.72e-031541824bfda1c41efbb86d829b3797d1168bf2587c3c97
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4F2 CYP4F3

1.72e-03154182f1fea1a87e977221fa125b62287368be9af4987d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PI15 EFEMP1

1.72e-03154182a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4F2 CYP4F3

1.72e-03154182b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CYP4F2 CYP4F3

1.72e-03154182160b170a3ade8b246843c9854af332475c047ba0
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

LRP1 CYP4F3

1.76e-03156182ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 EFEMP1

1.76e-03156182bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PI15 NOTCH3

1.78e-03157182c779a53b2c67d566f5d417e753cd17196a6bfd1c
ToppCellsevere_influenza-CD4+_T_naive|World / disease group, cell group and cell class (v2)

ZNF462 RNF157

1.81e-031581828ab3d8a9b7a1daa890d76dde1d6182af40b70021
ToppCellsevere_influenza-CD4+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

ZNF462 RNF157

1.81e-03158182ff3fa4bd06e01363429aec4bb587b95819bf0fc9
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|356C / Donor, Lineage, Cell class and subclass (all cells)

ZNF408 RNF157

1.83e-031591822fb1d2ff52920aeb48d048cf29f0cd45f944a73d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP9 PRR23D1

1.85e-03160182928d942b9f611fd4bd2faa660bf2809278495f23
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

PI15 NOTCH3

1.85e-0316018229c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 EFEMP1

1.88e-03161182a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

PI15 NOTCH3

1.88e-0316118247b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CYP4F2 CYP4F3

1.90e-03162182daacccf8b1374680803f49135673a00e09691cde
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP4F11 NOTCH3

1.90e-03162182112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PI15 NOTCH3

1.92e-0316318251dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF462 NOTCH3

1.92e-031631821c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CYP4F11 CYP4F3

1.94e-0316418281c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 CCDC168

1.97e-03165182cca3ba9d7d30404e3e683b8cfd500c348a4974b9
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4F11 CYP4F3

1.99e-03166182d96c562e1483adb4cdd817b68133f03356d7279b
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 EFEMP1

2.02e-031671823e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 EFEMP1

2.02e-031671823ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CYP4F12 EFEMP1

2.02e-031671825c0ede7783403f1c8004cf8c45785687e89046c6
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

LRP1 NOTCH3

2.04e-031681828ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF462 CCDC168

2.04e-03168182a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP9 RNF157

2.04e-0316818229a6c3ba69e03ccb19efb8ac177b9a162dc1ea43
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

CYP4F2 CYP4F3

2.04e-0316818204259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP9 RNF157

2.04e-031681824297be958a4754677df7cf73feba19b0d76f1b4a
ComputationalNeighborhood of GSTM1

CYP4F11 CYP4F2 CYP4F12

2.09e-04109123GNF2_GSTM1
ComputationalNeighborhood of LCAT

CYP4F11 CYP4F2 CYP4F12

3.06e-04124123GNF2_LCAT
ComputationalNeighborhood of HPN

CYP4F11 CYP4F2 CYP4F12

3.84e-04134123GNF2_HPN
ComputationalNeighborhood of HPX

CYP4F11 CYP4F2 CYP4F12

3.92e-04135123GNF2_HPX
Drugdichloran

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.62e-0841164CID000007430
Drugpropoxyphene

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.21e-0767164CID000010100
Drugcarteolol

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.63e-0772164CID000002583
Drugtrimipramine

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.49e-0780164CID000005584
Drugdiosmetin

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.18e-0785164CID005281612
Drugmephenytoin

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.66e-0788164CID000004060
Drugtienilic acid

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.57e-0793164CID000038409
Druglansoprazole

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.57e-0793164CID000003883
DrugAC1L1KIN

CYP4F11 CYP4F2 CYP4F12 CYP4F3

6.12e-07100164CID000005516
DrugSparteinum

CYP4F11 CYP4F2 CYP4F12 CYP4F3

6.37e-07101164CID000003966
Drugebastine

CYP4F2 CYP4F12 CYP4F3

6.49e-0725163CID000003191
DrugAC1Q7AUJ

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.15e-06117164CID000003303
Drug8-MOP

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.19e-06118164CID000004114
Drughexobarbital

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.60e-06127164CID000003608
Drugchloral hydrate

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.70e-06129164CID000002707
Drugaminoglutethimide

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.16e-06137164CID000002145
DrugAC1O5PIQ

CYP4F2 CYP4F12 CYP4F3

2.56e-0639163CID006438348
Drugparaoxon

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.41e-06164164CID000009395
Drugfelodipine

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.97e-06169164CID000003333
Drugaminopyrine

CYP4F11 CYP4F2 CYP4F12 CYP4F3

5.21e-06171164CID000006009
Drugmetyrapone

CYP4F11 CYP4F2 CYP4F12 CYP4F3

6.25e-06179164CID000004174
Drugalprazolam

CYP4F11 CYP4F2 CYP4F12 CYP4F3

8.41e-06193164CID000002118
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

LRP1 DICER1 LIMK1 CYP4F3

8.94e-061961645771_UP
Drugtolbutamide

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.30e-06198164CID000005505
Drug17-ODYA

CYP4F2 CYP4F12 CYP4F3

9.51e-0660163CID000001449
DrugMidodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; PC3; HT_HG-U133A

LRP1 LIMK1 NOTCH3 EFEMP1

9.68e-062001647156_UP
Drug3-hydroxystearate

CYP4F2 CYP4F12

9.70e-067162CID005282907
Drugdiclofenac

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.15e-05209164CID000003032
Drug2,2,2-trichloroethanol

CYP4F11 ARHGAP9 CYP4F12

1.72e-0573163CID000008259
Drug3 -hydroxypregn-5-en-20-one

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.92e-05238164CID000001027
Drug18-HETE

CYP4F2 CYP4F12

2.08e-0510162CID006442778
Drug6-trans-leukotriene B4

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.22e-05247164CID000000169
Drug2-naphthol

CYP4F11 ARHGAP9 CYP4F12

3.55e-0593163CID000008663
Drug3-hydroxyhexadecanoic acid

CYP4F2 CYP4F12

3.60e-0513162CID000301590
Drugazo analog I

CYP4F12 CYP4F3

3.60e-0513162CID006438575
Drug7-BFC

CYP4F2 CYP4F12

4.19e-0514162CID000848780
Drugdiamidine

CYP4F2 CYP4F3

4.84e-0515162CID000008813
Drug6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine

CYP4F2 CYP4F3 NOTCH3

4.97e-05104163ctd:C000595015
Drugrifampicin

CYP4F11 CYP4F2 CYP4F12 CYP4F3

5.13e-05306164CID005381226
Drug20-HETE

CYP4F2 CYP4F12 CYP4F3

5.26e-05106163CID005283157
Drugclofibrate

CYP4F11 CYP4F2 CYP4F12 CYP4F3

5.46e-05311164CID000002796
Drughalothane

CYP4F11 CYP4F2 CYP4F12 CYP4F3

5.67e-05314164CID000003562
DrugAC1L1AL2

CYP4F2 CYP4F12 CYP4F3

6.70e-05115163CID000001035
Drugpleuromutilin

CYP4F2 CYP4F12

7.04e-0518162CID000031326
DrugAzamulinum

CYP4F2 CYP4F12

7.04e-0518162CID003086060
Drugbenzphetamine

CYP4F11 CYP4F12 CYP4F3

7.42e-05119163CID000002341
DrugDB75

CYP4F2 CYP4F3

7.86e-0519162CID000126437
Drugdeferoxamine

CYP4F11 CYP4F2 CYP4F12 CYP4F3

7.98e-05343164CID000002973
Drugdioxin

CYP4F11 CYP4F2 CYP4F12 CYP4F3

8.35e-05347164CID000015625
Drug2-nitroimidazole

ARHGAP9 LIMK1 MGRN1

9.43e-05129163CID000010701
Drugphenobarbital

CYP4F11 CYP4F2 CYP4F12 CYP4F3

9.63e-05360164CID000004763
Drug20-hydroxyleukotriene B4

CYP4F2 CYP4F3

1.49e-0426162CID000001589
DrugC14845

CYP4F11 CYP4F12

1.61e-0427162CID011954064
DrugBP-9,10-oxide

CYP4F11 CYP4F12

1.61e-0427162CID000037456
DrugBrn 4136738

CYP4F11 CYP4F12

1.61e-0427162CID000050331
Drugnifedipine

CYP4F11 CYP4F2 CYP4F12 CYP4F3

1.66e-04415164CID000004485
Drug9-OH-BaP-4,5-oxide

CYP4F11 CYP4F12

1.73e-0428162CID000115064
Drug11-H-14,15-EETA

CYP4F11 CYP4F12

1.99e-0430162CID011954058
Drug19-hydroxytestosterone

CYP4F11 CYP4F12

1.99e-0430162CID000150968
Drugmelatonin

CYP4F11 ARHGAP9 CYP4F12 MGRN1

2.14e-04443164CID000000896
DrugBP-7,8-oxide

CYP4F11 CYP4F12

2.27e-0432162CID000037455
DrugK-K-K

CYP4F2 CYP4F12 CYP4F3

2.32e-04175163CID000003823
DrugTCEO

CYP4F11 CYP4F12

2.56e-0434162CID000028167
Drug12(13)-EpOME

CYP4F11 CYP4F12

2.56e-0434162CID000001416
DrugAC1O5XSP

CYP4F11 CYP4F12

2.56e-0434162CID006442739
DrugAC1L1CJI

CYP4F11 CYP4F12

2.72e-0435162CID000001929
DrugNSC98537

CYP4F11 CYP4F2 CYP4F12 CYP4F3

2.74e-04473164CID000005410
Drugcelastrol; Down 200; 2.5uM; MCF7; HT_HG-U133A_EA

DICER1 NOTCH3 EFEMP1

2.82e-04187163887_DN
Drug15-H-11,12-EETA

CYP4F11 CYP4F12

2.88e-0436162CID011954042
DrugAC1L3NGJ

CYP4F11 CYP4F12

2.88e-0436162CID000092121
Druglauric acid

CYP4F2 CYP4F12 CYP4F3

3.10e-04193163CID000003893
Drug5114445; Down 200; 10uM; MCF7; HT_HG-U133A_EA

DICER1 NOTCH3 EFEMP1

3.10e-04193163901_DN
DrugPNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A

LRP1 LIMK1 NOTCH3

3.19e-041951633732_DN
DrugEnoxacin [74011-58-8]; Down 200; 12.4uM; PC3; HT_HG-U133A

LRP1 LIMK1 NOTCH3

3.24e-041961634655_DN
DrugLevopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; PC3; HT_HG-U133A

CYP4F11 LIMK1 NOTCH3

3.29e-041971635083_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A

LRP1 ZNF408 NOTCH3

3.29e-041971636663_DN
DrugPropranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A

LRP1 DICER1 ZNF408

3.29e-041971636759_UP
DrugAminocaproic acid [60-32-2]; Up 200; 30.4uM; PC3; HT_HG-U133A

LIMK1 ZNF408 NOTCH3

3.29e-041971637258_UP
DrugDropropizine (R,S) [17692-31-8]; Down 200; 17uM; PC3; HT_HG-U133A

DICER1 LIMK1 NOTCH3

3.29e-041971635106_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ZNF408 NOTCH3 EFEMP1

3.34e-041981631061_DN
DrugTriamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A

LRP1 LIMK1 EFEMP1

3.34e-041981637307_UP
DrugCarbachol [51-83-2]; Down 200; 21.8uM; PC3; HT_HG-U133A

LRP1 ZNF408 NOTCH3

3.34e-041981636742_DN
DrugGuanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A

CYP4F11 LIMK1 NOTCH3

3.34e-041981635621_DN
DrugDacarbazine [4342-03-4]; Up 200; 22uM; MCF7; HT_HG-U133A

DICER1 LIMK1 CYP4F12

3.34e-041981632754_UP
Drugoxygen

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.36e-04499164CID000000977
Drug11,14,15-THET

CYP4F11 CYP4F12

3.38e-0439162CID006439531
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; MCF7; HT_HG-U133A

LRP1 DICER1 CYP4F12

3.39e-041991635686_UP
DrugBenzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; HL60; HT_HG-U133A

LRP1 CYP4F11 LIMK1

3.39e-041991636155_UP
DrugBenoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A

LIMK1 CYP4F12 NOTCH3

3.39e-041991634115_UP
DrugEtodolac [41340-25-4]; Up 200; 14uM; PC3; HT_HG-U133A

LRP1 ZNF408 NOTCH3

3.39e-041991637246_UP
DrugClindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A

ZNF408 NOTCH3 MGRN1

3.39e-041991632057_DN
DrugMetrizamide [31112-62-6]; Down 200; 5uM; PC3; HT_HG-U133A

LRP1 LIMK1 ZNF408

3.44e-042001634075_DN
DrugAC1L1HMM

CYP4F11 CYP4F2 CYP4F12 CYP4F3

3.82e-04516164CID000004196
Drug11,12,15-trihydroxyeicosatrienoic acid

CYP4F11 CYP4F12

3.92e-0442162CID006439610
DrugNADP(H

CYP4F11 CYP4F2 CYP4F12 CYP4F3

4.14e-04527164CID000000930
Drugnaphthalene-1,2-dihydrodiol

CYP4F11 CYP4F12

4.50e-0445162CID000000362
DrugC14802

CYP4F11 CYP4F12

4.91e-0447162CID011954053
DrugFuran

CYP4F2 CYP4F3

4.91e-0447162CID000008029
DrugC14800

CYP4F11 CYP4F12

5.13e-0448162CID011954051
Drugnitro-L

CYP4F11 CYP4F12

5.13e-0448162CID000006849
Diseasehexadecenedioate (C16:1-DC) measurement

CYP4F11 CYP4F2

9.90e-069162EFO_0800562
DiseaseMigraine Disorders

LRP1 NOTCH3

2.14e-0513162C0149931
Diseasecolon carcinoma

PI15 ARHGAP9

8.89e-0526162EFO_1001950
Diseasehypertension (biomarker_via_orthology)

CYP4F11 CYP4F2 CYP4F12

2.34e-04227163DOID:10763 (biomarker_via_orthology)
Diseaseaortic measurement

LRP1 PI15 LIMK1

3.14e-04251163EFO_0020865
Diseasepulse pressure measurement

LRP1 PI15 LIMK1 NOTCH3 EFEMP1

6.55e-041392165EFO_0005763
Diseasemigraine disorder, Headache

LRP1 ZNF462

9.81e-0486162HP_0002315, MONDO_0005277
Diseasedescending aortic diameter

LRP1 PI15

1.03e-0388162EFO_0021788
DiseaseBMI-adjusted waist circumference, physical activity measurement

ZNF462 EFEMP1

1.99e-03123162EFO_0007789, EFO_0008002

Protein segments in the cluster

PeptideGeneStartEntry
CLRDSYPRPDQPCYL

DICER1

756

Q9UPY3
ARFVCPPNRPFRCKN

LRP1

3691

Q07954
LRYQANNCPICRLPF

MGRN1

306

O60291
RPAPLAPFFRCACAQ

NOTCH3

1351

Q9UM47
FYDNCRRLQCFPQPP

CYP4F11

41

Q9HBI6
FYNNCRRLQCFPQPP

CYP4F12

41

Q9HCS2
FYDNCRRLRCFPQPP

CYP4F2

41

P78329
FYDNCCRLRCFPQPP

CYP4F3

41

Q08477
FPPPPFYLNCDTRRN

CCDC168

4946

Q8NDH2
RCRAAFPQCYPLPPT

PRR23D1

206

E9PI22
GFRCYPRNPCQDPYI

EFEMP1

356

Q12805
RYQANNCPICRLPFR

RNF157

306

Q96PX1
RCRAAFPQCYPLPPT

PRR23D2

206

P0DMB1
ERPFPCPQCGRAYTL

ZNF408

576

Q9H9D4
YCNLVDLRRCPRSPP

ARHGAP9

191

Q9BRR9
PFRRFMNRFQCPFCP

ZNF462

431

Q96JM2
FPYPQDCNPRCPMRC

PI15

151

O43692
LNVRGFLDRYCPPNC

LIMK1

561

P53667