| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | transmembrane-ephrin receptor activity | 3.65e-04 | 15 | 38 | 2 | GO:0005005 | |
| GeneOntologyMolecularFunction | kinase activity | 5.23e-04 | 764 | 38 | 7 | GO:0016301 | |
| GeneOntologyMolecularFunction | ephrin receptor activity | 5.91e-04 | 19 | 38 | 2 | GO:0005003 | |
| Domain | SAM/pointed | 2.47e-06 | 117 | 35 | 5 | IPR013761 | |
| Domain | SAM | 2.15e-05 | 88 | 35 | 4 | SM00454 | |
| Domain | SAM_DOMAIN | 2.91e-05 | 95 | 35 | 4 | PS50105 | |
| Domain | SAM | 3.16e-05 | 97 | 35 | 4 | IPR001660 | |
| Domain | - | 4.48e-05 | 106 | 35 | 4 | 1.10.150.50 | |
| Domain | SAM_1 | 2.78e-04 | 68 | 35 | 3 | PF00536 | |
| Domain | RECEPTOR_TYR_KIN_V_2 | 3.06e-04 | 14 | 35 | 2 | PS00791 | |
| Domain | RECEPTOR_TYR_KIN_V_1 | 3.06e-04 | 14 | 35 | 2 | PS00790 | |
| Domain | EphA2_TM | 3.06e-04 | 14 | 35 | 2 | PF14575 | |
| Domain | Tyr_kinase_ephrin_rcpt | 3.06e-04 | 14 | 35 | 2 | IPR016257 | |
| Domain | Eph_TM | 3.06e-04 | 14 | 35 | 2 | IPR027936 | |
| Domain | Ephrin_rcpt_lig-bd_dom | 3.06e-04 | 14 | 35 | 2 | IPR001090 | |
| Domain | Tyr_kinase_rcpt_V_CS | 3.06e-04 | 14 | 35 | 2 | IPR001426 | |
| Domain | EPH_LBD | 3.06e-04 | 14 | 35 | 2 | PS51550 | |
| Domain | EPH_lbd | 3.06e-04 | 14 | 35 | 2 | SM00615 | |
| Domain | Ephrin_lbd | 3.06e-04 | 14 | 35 | 2 | PF01404 | |
| Domain | Ephrin_rec_like | 9.96e-04 | 25 | 35 | 2 | SM01411 | |
| Domain | Tyr-kin_ephrin_A/B_rcpt-like | 9.96e-04 | 25 | 35 | 2 | IPR011641 | |
| Domain | PROTEIN_KINASE_ATP | 1.55e-03 | 459 | 35 | 5 | PS00107 | |
| Domain | Prot_kinase_dom | 2.05e-03 | 489 | 35 | 5 | IPR000719 | |
| Domain | PROTEIN_KINASE_DOM | 2.12e-03 | 493 | 35 | 5 | PS50011 | |
| Domain | Kinase-like_dom | 3.19e-03 | 542 | 35 | 5 | IPR011009 | |
| Domain | Protein_kinase_ATP_BS | 5.32e-03 | 379 | 35 | 4 | IPR017441 | |
| Domain | SH3 | 7.60e-03 | 216 | 35 | 3 | PS50002 | |
| Domain | SH3 | 7.60e-03 | 216 | 35 | 3 | SM00326 | |
| Domain | SH3_domain | 7.99e-03 | 220 | 35 | 3 | IPR001452 | |
| Domain | - | 8.25e-03 | 73 | 35 | 2 | 2.60.120.260 | |
| Domain | SH3_2 | 1.13e-02 | 86 | 35 | 2 | IPR011511 | |
| Domain | SH3_2 | 1.13e-02 | 86 | 35 | 2 | PF07653 | |
| Domain | TyrKc | 1.18e-02 | 88 | 35 | 2 | SM00219 | |
| Domain | Tyr_kinase_cat_dom | 1.18e-02 | 88 | 35 | 2 | IPR020635 | |
| Domain | Galactose-bd-like | 1.34e-02 | 94 | 35 | 2 | IPR008979 | |
| Domain | PROTEIN_KINASE_TYR | 1.42e-02 | 97 | 35 | 2 | PS00109 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | MICALL1 KDM3B PRR12 SCAF1 DLX2 TBKBP1 SHANK2 FBXO46 CASKIN1 ZNF408 PKN3 MARK4 | 1.77e-09 | 1105 | 39 | 12 | 35748872 |
| Pubmed | Dendritic spine morphology and memory formation depend on postsynaptic Caskin proteins. | 3.67e-06 | 3 | 39 | 2 | 31727973 | |
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | 4.26e-06 | 861 | 39 | 8 | 36931259 | |
| Pubmed | Sequential assembly of centromeric proteins in male mouse meiosis. | 3.42e-05 | 8 | 39 | 2 | 19283064 | |
| Pubmed | 5.48e-05 | 10 | 39 | 2 | 25073978 | ||
| Pubmed | EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes. | 5.48e-05 | 10 | 39 | 2 | 16547242 | |
| Pubmed | 9.36e-05 | 78 | 39 | 3 | 17192257 | ||
| Pubmed | A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. | 1.03e-04 | 420 | 39 | 5 | 28065597 | |
| Pubmed | 1.34e-04 | 233 | 39 | 4 | 37704626 | ||
| Pubmed | 1.85e-04 | 18 | 39 | 2 | 24803655 | ||
| Pubmed | Sp9 Regulates Medial Ganglionic Eminence-Derived Cortical Interneuron Development. | 3.33e-04 | 24 | 39 | 2 | 29878134 | |
| Pubmed | 3.91e-04 | 26 | 39 | 2 | 15454262 | ||
| Pubmed | A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. | 5.10e-04 | 331 | 39 | 4 | 19490893 | |
| Pubmed | HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages. | 5.95e-04 | 32 | 39 | 2 | 27114546 | |
| Pubmed | 6.08e-04 | 347 | 39 | 4 | 17114649 | ||
| Pubmed | MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development. | 6.83e-04 | 358 | 39 | 4 | 32460013 | |
| Pubmed | 1.03e-03 | 42 | 39 | 2 | 35705031 | ||
| Interaction | TOP3B interactions | MICALL1 KDM3B PRR12 SCAF1 DLX2 TBKBP1 SHANK2 FBXO46 CASKIN1 ZNF408 PKN3 MARK4 | 9.85e-06 | 1470 | 38 | 12 | int:TOP3B |
| Cytoband | 5q34 | 3.43e-04 | 32 | 39 | 2 | 5q34 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19q13 | 4.74e-04 | 1192 | 39 | 6 | chr19q13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr7q22 | 8.62e-04 | 219 | 39 | 3 | chr7q22 | |
| Cytoband | 9q34.11 | 9.43e-04 | 53 | 39 | 2 | 9q34.11 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1p34 | 2.00e-03 | 294 | 39 | 3 | chr1p34 | |
| Cytoband | 19q13.3 | 2.24e-03 | 82 | 39 | 2 | 19q13.3 | |
| Cytoband | 7q22.1 | 4.19e-03 | 113 | 39 | 2 | 7q22.1 | |
| GeneFamily | Sterile alpha motif domain containing | 7.22e-06 | 88 | 26 | 4 | 760 | |
| GeneFamily | Fibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors | 1.79e-04 | 14 | 26 | 2 | 1095 | |
| Drug | retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA | 9.41e-06 | 167 | 39 | 5 | 966_UP | |
| Drug | Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; HL60; HG-U133A | 1.80e-05 | 191 | 39 | 5 | 1417_UP | |
| Drug | Norethindrone [68-22-4]; Up 200; 13.4uM; HL60; HT_HG-U133A | 1.85e-05 | 192 | 39 | 5 | 2383_UP | |
| Drug | Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A | 1.99e-05 | 195 | 39 | 5 | 7362_DN | |
| Drug | Azaperone [1649-18-9]; Down 200; 12.2uM; PC3; HT_HG-U133A | 2.04e-05 | 196 | 39 | 5 | 5877_DN | |
| Drug | Ethamsylate [2624-44-4]; Down 200; 15.2uM; PC3; HT_HG-U133A | 2.14e-05 | 198 | 39 | 5 | 4576_DN | |
| Drug | Tremorine dihydrochloride [300-68-5]; Down 200; 15uM; MCF7; HT_HG-U133A | 2.14e-05 | 198 | 39 | 5 | 3196_DN | |
| Drug | Telenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; HL60; HT_HG-U133A | 2.19e-05 | 199 | 39 | 5 | 2388_UP | |
| Disease | Intellectual Disability | 2.14e-05 | 447 | 38 | 6 | C3714756 | |
| Disease | Abnormal behavior | 1.92e-04 | 16 | 38 | 2 | C0233514 | |
| Disease | immature granulocyte count | 2.17e-04 | 17 | 38 | 2 | EFO_0803542 | |
| Disease | Global developmental delay | 6.73e-04 | 133 | 38 | 3 | C0557874 | |
| Disease | vitamin D measurement | 8.98e-04 | 336 | 38 | 4 | EFO_0004631 | |
| Disease | autistic disorder (is_implicated_in) | 1.35e-03 | 42 | 38 | 2 | DOID:12849 (is_implicated_in) | |
| Disease | Alzheimer disease | 3.42e-03 | 485 | 38 | 4 | MONDO_0004975 | |
| Disease | family history of Alzheimer’s disease | 3.79e-03 | 71 | 38 | 2 | EFO_0009268 | |
| Disease | Autistic Disorder | 4.59e-03 | 261 | 38 | 3 | C0004352 | |
| Disease | Hodgkins lymphoma | 5.03e-03 | 82 | 38 | 2 | EFO_0000183 | |
| Disease | Neurodevelopmental Disorders | 6.42e-03 | 93 | 38 | 2 | C1535926 | |
| Disease | phosphatidylinositol measurement | 6.69e-03 | 95 | 38 | 2 | EFO_0010230 | |
| Disease | Retinitis Pigmentosa | 7.96e-03 | 104 | 38 | 2 | C0035334 | |
| Disease | calcium measurement | 8.46e-03 | 628 | 38 | 4 | EFO_0004838 | |
| Disease | R-6-hydroxywarfarin measurement | 9.50e-03 | 114 | 38 | 2 | EFO_0803327 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| APASRPKPRPSPSST | 766 | Q92888 | |
| AAPPCSPLLKAPSPA | 176 | Q15744 | |
| ASPPCASPPVSAPAS | 226 | Q07687 | |
| CRPSPSPVSPASNPR | 126 | Q9ULK2 | |
| PPPPPKRSSSALASA | 946 | Q8WXD9 | |
| LQPPRSKTPSSPCPA | 471 | Q9NQS7 | |
| PRSSLSSPSPPCSPL | 536 | Q8IX03 | |
| KAPRPPGQPPRASSC | 446 | Q9HAT1 | |
| PPPCQSPASLSEPRK | 341 | Q5VYM1 | |
| PSQHPPSPPKRCLSY | 951 | O95382 | |
| RPPSAALKPSACPEP | 26 | Q6PJ61 | |
| PSLPRSCGPKLTNSP | 21 | Q16875 | |
| KAIRPPCPDTAPPSS | 1206 | Q7LBC6 | |
| CPPSPHLENPPKSST | 1441 | Q8IZD2 | |
| PTLQCPPPSSPEKAA | 276 | Q96N66 | |
| SPPRKGLAPCSPPSV | 116 | Q8N3F8 | |
| PAELTPRSTPPHPCS | 406 | A4D2B8 | |
| PTDPPSASCTRPPSA | 326 | Q5JZY3 | |
| RPPSPPKACSTPGSC | 141 | Q53FE4 | |
| DPPSMACTRPPSSPR | 316 | P29320 | |
| AARQCAPPPAPPTSS | 101 | P31276 | |
| CGPSPAPLHPKRSPT | 426 | Q96L34 | |
| PLKAIPCSSSAPPLP | 211 | Q8TC76 | |
| CPPKSPVQCLPPASS | 21 | Q9BYE3 | |
| KRPSPPPSGAPCLNS | 266 | Q12951 | |
| PACPSAGCPRSSPSP | 141 | Q8IY34 | |
| KQFSVPPAPTRPSCP | 141 | Q99661 | |
| SSPSLPPASPCPALA | 296 | Q9BUN1 | |
| SSPSTISPPKGCPRT | 466 | Q6P5Z2 | |
| CSGSSPPRVKSSTPP | 891 | Q9UQ35 | |
| RPCSPASAPAPTSPK | 81 | Q8IXR5 | |
| PSRPVSTSASKPCLP | 81 | Q2M3A8 | |
| PPPPRSTATPKCQSL | 406 | Q9ULL5 | |
| PSPTTYNCPKSPTPR | 901 | Q9UPX8 | |
| PPRAAACPSSPHKIP | 886 | O43295 | |
| KAPAPAPPPSGSTSC | 661 | Q9H7N4 | |
| SPSDQCPPRAKTPEP | 311 | Q9H9D4 | |
| PAEAQPPSPRSSSPC | 361 | Q9Y2K6 | |
| LCPSPAQSPRSASPP | 186 | F5GYI3 | |
| ITRHSSPACLPPPPK | 121 | O95789 | |
| PASPSCPSPVPQRRS | 386 | A7MCY6 |