Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	BICD2 CACNA1C CACNA1D MYH4 SHROOM1 ALMS1 MYH14 MICAL2 TLN1 CAPG ARFGEF1 ARPC5L JAKMIP3 KIF13A TBC1D21 AGBL1	2.47e-08	1099	55	16	GO:0008092
GeneOntologyMolecularFunction	actin filament binding	MYH4 SHROOM1 MYH14 TLN1 CAPG ARPC5L	3.68e-05	227	55	6	GO:0051015
GeneOntologyMolecularFunction	actin binding	MYH4 SHROOM1 MYH14 MICAL2 TLN1 CAPG ARPC5L TBC1D21	4.68e-05	479	55	8	GO:0003779
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1C CACNA1D	7.41e-05	5	55	2	GO:0086007
GeneOntologyMolecularFunction	alpha-actinin binding	CACNA1C CACNA1D ALMS1	8.42e-05	31	55	3	GO:0051393
GeneOntologyMolecularFunction	actinin binding	CACNA1C CACNA1D ALMS1	2.26e-04	43	55	3	GO:0042805
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH4 MYH14 KIF13A DYNC1H1	3.13e-04	118	55	4	GO:0003774
GeneOntologyMolecularFunction	glycosphingolipid binding	LAMA1 LAMC1	5.70e-04	13	55	2	GO:0043208
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1D	6.64e-04	14	55	2	GO:0008331
GeneOntologyMolecularFunction	ATP-dependent activity	MYH4 UBA1 MYH14 TOR4A SMC2 KIF13A DYNC1H1	1.42e-03	614	55	7	GO:0140657
GeneOntologyMolecularFunction	dynein light intermediate chain binding	BICD2 DYNC1H1	2.69e-03	28	55	2	GO:0051959
GeneOntologyBiologicalProcess	actin filament-based process	CACNA1C CACNA1D MYH4 SHROOM1 ALMS1 MYH14 MICAL2 KANK3 TLN1 SCN2A CAPG ARFGEF1 ARPC5L MYH16	1.01e-07	912	56	14	GO:0030029
GeneOntologyBiologicalProcess	microtubule-based movement	BICD2 ENO4 CLUAP1 AKAP4 RSPH4A KIF13A TBC1D21 DYNC1H1	5.22e-05	493	56	8	GO:0007018
GeneOntologyBiologicalProcess	actin cytoskeleton organization	SHROOM1 ALMS1 MYH14 MICAL2 KANK3 TLN1 CAPG ARFGEF1 ARPC5L MYH16	5.30e-05	803	56	10	GO:0030036
GeneOntologyBiologicalProcess	actin filament-based movement	CACNA1C CACNA1D MYH4 MYH14 SCN2A	5.92e-05	153	56	5	GO:0030048
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	CACNA1C CACNA1D	7.20e-05	5	56	2	GO:1904879
GeneOntologyBiologicalProcess	microtubule-based process	BICD2 ENO4 CLUAP1 AKAP4 ALMS1 RSPH4A NCKAP5 CUL7 KIF13A TBC1D21 DYNC1H1	1.09e-04	1058	56	11	GO:0007017
GeneOntologyBiologicalProcess	membrane depolarization during action potential	CACNA1C CACNA1D SCN2A	1.27e-04	36	56	3	GO:0086010
GeneOntologyBiologicalProcess	supramolecular fiber organization	SHROOM1 ALMS1 MICAL2 KANK3 CAPG ARFGEF1 ARPC5L NCKAP5 MYH16 DYNC1H1	2.25e-04	957	56	10	GO:0097435
GeneOntologyBiologicalProcess	cilium organization	ENO4 CLUAP1 AKAP4 ALMS1 RSPH4A TTC39C TBC1D21	2.91e-04	476	56	7	GO:0044782
GeneOntologyBiologicalProcess	glucose homeostasis	VGF CACNA1C CACNA1D ALMS1 BECN2 HCFC1	3.02e-04	338	56	6	GO:0042593
GeneOntologyBiologicalProcess	carbohydrate homeostasis	VGF CACNA1C CACNA1D ALMS1 BECN2 HCFC1	3.07e-04	339	56	6	GO:0033500
GeneOntologyBiologicalProcess	actin polymerization or depolymerization	MICAL2 KANK3 CAPG ARFGEF1 ARPC5L	3.37e-04	222	56	5	GO:0008154
GeneOntologyBiologicalProcess	regulation of basement membrane organization	LAMA1 LAMC1	3.92e-04	11	56	2	GO:0110011
GeneOntologyBiologicalProcess	actin-mediated cell contraction	CACNA1C CACNA1D MYH4 SCN2A	3.93e-04	127	56	4	GO:0070252
GeneOntologyBiologicalProcess	actin filament organization	SHROOM1 ALMS1 MICAL2 KANK3 CAPG ARFGEF1 ARPC5L	4.36e-04	509	56	7	GO:0007015
GeneOntologyBiologicalProcess	microtubule-based transport	BICD2 CLUAP1 RSPH4A KIF13A DYNC1H1	6.12e-04	253	56	5	GO:0099111
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	CACNA1C CACNA1D SCN2A	6.40e-04	62	56	3	GO:0086002
GeneOntologyBiologicalProcess	positive regulation of integrin-mediated signaling pathway	LAMA1 LAMC1	6.45e-04	14	56	2	GO:2001046
GeneOntologyBiologicalProcess	microtubule bundle formation	CLUAP1 RSPH4A NCKAP5 TBC1D21	6.48e-04	145	56	4	GO:0001578
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	BICD2 CLUAP1 ALMS1 RSPH4A NCKAP5 CUL7 TBC1D21 DYNC1H1	6.85e-04	720	56	8	GO:0000226
GeneOntologyBiologicalProcess	cilium movement	ENO4 AKAP4 RSPH4A TBC1D21 DYNC1H1	7.04e-04	261	56	5	GO:0003341
GeneOntologyBiologicalProcess	single strand break repair	XNDC1N SMC2	7.43e-04	15	56	2	GO:0000012
GeneOntologyBiologicalProcess	positive regulation of membrane depolarization	CACNA1C CACNA1D	8.48e-04	16	56	2	GO:1904181
GeneOntologyBiologicalProcess	regulation of actin filament polymerization	KANK3 CAPG ARFGEF1 ARPC5L	8.52e-04	156	56	4	GO:0030833
GeneOntologyBiologicalProcess	regulation of cytoskeleton organization	BICD2 ALMS1 KANK3 CAPG ARFGEF1 ARPC5L DYNC1H1	9.33e-04	579	56	7	GO:0051493
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	KANK3 CAPG ARFGEF1	1.11e-03	75	56	3	GO:0030837
GeneOntologyCellularComponent	laminin-1 complex	LAMA1 LAMC1	2.11e-05	3	56	2	GO:0005606
GeneOntologyCellularComponent	laminin complex	LAMA1 LAMC1	3.13e-04	10	56	2	GO:0043256
GeneOntologyCellularComponent	NSL complex	KANSL1 HCFC1	3.82e-04	11	56	2	GO:0044545
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1C CACNA1D	4.57e-04	12	56	2	GO:1990454
GeneOntologyCellularComponent	myosin complex	MYH4 MYH14 MYH16	5.32e-04	59	56	3	GO:0016459
GeneOntologyCellularComponent	actin cytoskeleton	MYH4 SHROOM1 MYH14 MICAL2 CAPG ARPC5L MYH16	8.37e-04	576	56	7	GO:0015629
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMA1 LAMC1	9.34e-04	17	56	2	GO:0098637
GeneOntologyCellularComponent	supramolecular fiber	CACNA1C CACNA1D MYH4 AKAP4 SHROOM1 MYH14 MICAL2 NCKAP5 KIF13A DYNC1H1	1.04e-03	1179	56	10	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	CACNA1C CACNA1D MYH4 AKAP4 SHROOM1 MYH14 MICAL2 NCKAP5 KIF13A DYNC1H1	1.09e-03	1187	56	10	GO:0099081
GeneOntologyCellularComponent	T-tubule	CACNA1C CACNA1D SCN2A	1.25e-03	79	56	3	GO:0030315
GeneOntologyCellularComponent	extrinsic component of postsynaptic membrane	VWC2 FBXO2	1.57e-03	22	56	2	GO:0098890
HumanPheno	Decreased patellar reflex	BICD2 MYH14 DYNC1H1	2.45e-06	10	15	3	HP:0011808
HumanPheno	Spinal muscular atrophy	BICD2 UBA1 DYNC1H1	3.53e-05	23	15	3	HP:0007269
MousePheno	thin cerebral cortex	BICD2 ARFGEF1 LAMC1 HCFC1 DYNC1H1	6.16e-06	100	37	5	MP:0006254
Domain	CAC1F_C	CACNA1C CACNA1D	2.10e-05	3	50	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D	2.10e-05	3	50	2	PF16885
Domain	VDCC_L_a1su	CACNA1C CACNA1D	4.20e-05	4	50	2	IPR005446
Domain	Galactose-bd-like	LAMA1 LAMC1 CUL7 FBXO2	1.16e-04	94	50	4	IPR008979
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D	1.46e-04	7	50	2	IPR014873
Domain	GPHH	CACNA1C CACNA1D	1.46e-04	7	50	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D	1.46e-04	7	50	2	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1D	1.46e-04	7	50	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D	1.46e-04	7	50	2	PF08763
Domain	LAMININ_IVA	LAMA1 LAMC1	1.95e-04	8	50	2	PS51115
Domain	Laminin_B	LAMA1 LAMC1	1.95e-04	8	50	2	PF00052
Domain	LamB	LAMA1 LAMC1	1.95e-04	8	50	2	SM00281
Domain	Laminin_IV	LAMA1 LAMC1	1.95e-04	8	50	2	IPR000034
Domain	VDCCAlpha1	CACNA1C CACNA1D	3.12e-04	10	50	2	IPR002077
Domain	Channel_four-helix_dom	CACNA1C CACNA1D SCN2A	4.77e-04	57	50	3	IPR027359
Domain	-	CACNA1C CACNA1D SCN2A	4.77e-04	57	50	3	1.20.120.350
Domain	Myosin_N	MYH4 MYH14	7.21e-04	15	50	2	PF02736
Domain	-	ARFGEF1 PSD4	7.21e-04	15	50	2	1.10.1000.11
Domain	Sec7	ARFGEF1 PSD4	7.21e-04	15	50	2	PF01369
Domain	Myosin_N	MYH4 MYH14	7.21e-04	15	50	2	IPR004009
Domain	Sec7_alpha_orthog	ARFGEF1 PSD4	7.21e-04	15	50	2	IPR023394
Domain	Sec7	ARFGEF1 PSD4	8.23e-04	16	50	2	SM00222
Domain	Laminin_N	LAMA1 LAMC1	8.23e-04	16	50	2	IPR008211
Domain	SEC7	ARFGEF1 PSD4	8.23e-04	16	50	2	PS50190
Domain	LAMININ_NTER	LAMA1 LAMC1	8.23e-04	16	50	2	PS51117
Domain	Sec7_dom	ARFGEF1 PSD4	8.23e-04	16	50	2	IPR000904
Domain	Laminin_N	LAMA1 LAMC1	8.23e-04	16	50	2	PF00055
Domain	LamNT	LAMA1 LAMC1	8.23e-04	16	50	2	SM00136
Domain	-	LAMC1 CUL7 FBXO2	9.84e-04	73	50	3	2.60.120.260
Domain	Myosin_tail_1	MYH4 MYH14	1.05e-03	18	50	2	PF01576
Domain	Myosin_tail	MYH4 MYH14	1.05e-03	18	50	2	IPR002928
Domain	Myosin-like_IQ_dom	MYH4 MYH14	1.17e-03	19	50	2	IPR027401
Domain	-	MYH4 MYH14	1.17e-03	19	50	2	4.10.270.10
Domain	IQ	MYH4 MYH14 SCN2A	1.33e-03	81	50	3	SM00015
Domain	IQ_motif_EF-hand-BS	MYH4 MYH14 SCN2A	1.80e-03	90	50	3	IPR000048
Domain	IQ	MYH4 MYH14 SCN2A	1.98e-03	93	50	3	PS50096
Domain	EGF_LAM_2	LAMA1 LAMC1	2.91e-03	30	50	2	PS50027
Domain	EGF_LAM_1	LAMA1 LAMC1	2.91e-03	30	50	2	PS01248
Domain	Ion_trans_dom	CACNA1C CACNA1D SCN2A	3.52e-03	114	50	3	IPR005821
Domain	Ion_trans	CACNA1C CACNA1D SCN2A	3.52e-03	114	50	3	PF00520
Domain	Laminin_EGF	LAMA1 LAMC1	3.95e-03	35	50	2	PF00053
Domain	EGF_Lam	LAMA1 LAMC1	3.95e-03	35	50	2	SM00180
Domain	Myosin_head_motor_dom	MYH4 MYH14	4.64e-03	38	50	2	IPR001609
Domain	MYOSIN_MOTOR	MYH4 MYH14	4.64e-03	38	50	2	PS51456
Domain	Myosin_head	MYH4 MYH14	4.64e-03	38	50	2	PF00063
Domain	Laminin_EGF	LAMA1 LAMC1	4.64e-03	38	50	2	IPR002049
Domain	MYSc	MYH4 MYH14	4.64e-03	38	50	2	SM00242
Domain	P-loop_NTPase	MYH4 MYH14 TOR4A SMC2 KIF13A DYNC1H1 MPP7	7.06e-03	848	50	7	IPR027417
Pubmed	Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.	TLN1 SMC2 HCFC1 DYNC1H1	2.23e-06	57	56	4	38223760
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	2.55e-06	2	56	2	24849370
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	2.55e-06	2	56	2	20014384
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	2.55e-06	2	56	2	26049024
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	2.55e-06	2	56	2	17015854
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	2.55e-06	2	56	2	30001160
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	2.55e-06	2	56	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	2.55e-06	2	56	2	16706838
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	2.55e-06	2	56	2	23761887
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	2.55e-06	2	56	2	14981074
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	2.55e-06	2	56	2	21352396
Pubmed	Gene mapping of mouse laminin A and B2 subunits using mouse-Chinese hamster somatic cell hybrids.	LAMA1 LAMC1	2.55e-06	2	56	2	2267633
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	2.55e-06	2	56	2	25292336
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	2.55e-06	2	56	2	17526649
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	2.55e-06	2	56	2	12606379
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	2.55e-06	2	56	2	24941892
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	2.55e-06	2	56	2	21054386
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	2.55e-06	2	56	2	17409250
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	2.55e-06	2	56	2	16267232
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	2.55e-06	2	56	2	24848473
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	2.55e-06	2	56	2	22826131
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	2.55e-06	2	56	2	24996399
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	2.55e-06	2	56	2	24470632
Pubmed	Laminin chain-specific gene expression during mouse oocyte maturation.	LAMA1 LAMC1	2.55e-06	2	56	2	9291468
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	2.55e-06	2	56	2	24760982
Pubmed	Differential distribution of laminins in Alzheimer disease and normal human brain tissue.	LAMA1 LAMC1	2.55e-06	2	56	2	12111806
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	2.55e-06	2	56	2	24086669
Pubmed	Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression.	LAMA1 LAMC1	7.63e-06	3	56	2	2100263
Pubmed	The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.	CACNA1C CACNA1D	7.63e-06	3	56	2	19351867
Pubmed	Identification of laminin domains involved in branching morphogenesis: effects of anti-laminin monoclonal antibodies on mouse embryonic lung development.	LAMA1 LAMC1	7.63e-06	3	56	2	1907584
Pubmed	Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.	CACNA1C CACNA1D	7.63e-06	3	56	2	21832054
Pubmed	Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.	LAMA1 LAMC1	7.63e-06	3	56	2	7698745
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1D	7.63e-06	3	56	2	17289261
Pubmed	Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells.	LAMA1 LAMC1	7.63e-06	3	56	2	1292752
Pubmed	Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia.	LAMA1 LAMC1	7.63e-06	3	56	2	7669546
Pubmed	Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.	CACNA1C CACNA1D	7.63e-06	3	56	2	23973784
Pubmed	Three-dimensional analysis of the developing pituitary gland in the mouse.	LAMA1 LAMC1	7.63e-06	3	56	2	9603432
Pubmed	Expression of laminin chains during myogenic differentiation.	LAMA1 LAMC1	7.63e-06	3	56	2	7510707
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	7.63e-06	3	56	2	26831068
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D	7.63e-06	3	56	2	17767505
Pubmed	An association of IgG anti-laminin-1 autoantibodies with endometriosis in infertile patients.	LAMA1 LAMC1	7.63e-06	3	56	2	12615822
Pubmed	Differential expression of laminin, nidogen and collagen IV genes in the midgestation mouse placenta.	LAMA1 LAMC1	7.63e-06	3	56	2	8153091
Pubmed	MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.	CACNA1C CACNA1D	7.63e-06	3	56	2	31302118
Pubmed	Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.	CACNA1C CACNA1D	7.63e-06	3	56	2	23045342
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	7.63e-06	3	56	2	23338940
Pubmed	Differential expression of laminin A and B chains during development of embryonic mouse organs.	LAMA1 LAMC1	7.63e-06	3	56	2	2088723
Pubmed	Laminin-121--recombinant expression and interactions with integrins.	LAMA1 LAMC1	7.63e-06	3	56	2	20566382
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D	7.63e-06	3	56	2	2173707
Pubmed	Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.	CACNA1C CACNA1D	7.63e-06	3	56	2	24934288
Pubmed	Global landscape of HIV-human protein complexes.	BICD2 UBA1 MAGED1 ALMS1 ARFGEF1 MRPL11 DYNC1H1	8.60e-06	457	56	7	22190034
Pubmed	Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.	LAMA1 LAMC1	1.52e-05	4	56	2	12820173
Pubmed	Role of laminin terminal globular domains in basement membrane assembly.	LAMA1 LAMC1	1.52e-05	4	56	2	17517882
Pubmed	Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.	LAMA1 LAMC1	1.52e-05	4	56	2	9299121
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1D	1.52e-05	4	56	2	20937870
Pubmed	Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy.	LAMA1 LAMC1	1.52e-05	4	56	2	19074617
Pubmed	Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation.	LAMA1 LAMC1	1.52e-05	4	56	2	9885251
Pubmed	Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family.	MYH14 MYH16	1.52e-05	4	56	2	11919279
Pubmed	Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.	CACNA1C CACNA1D	1.52e-05	4	56	2	17110593
Pubmed	Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.	LAMA1 LAMC1	1.52e-05	4	56	2	8034675
Pubmed	Depletion of nuclear actin is a key mediator of quiescence in epithelial cells.	LAMA1 LAMC1	1.52e-05	4	56	2	21172822
Pubmed	The expression of the genes for entactin, laminin A, laminin B1 and laminin B2 in murine lens morphogenesis and eye development.	LAMA1 LAMC1	2.54e-05	5	56	2	1725162
Pubmed	Expression of laminin and nidogen genes during the postimplantation development of the mouse placenta.	LAMA1 LAMC1	2.54e-05	5	56	2	8286607
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA1 LAMC1	2.54e-05	5	56	2	11969289
Pubmed	Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo.	LAMA1 LAMC1	2.54e-05	5	56	2	8359228
Pubmed	Expression of collagen alpha 1(IV), laminin and nidogen genes in the embryonic mouse lung: implications for branching morphogenesis.	LAMA1 LAMC1	2.54e-05	5	56	2	7516699
Pubmed	A single linkage group comprising 11 polymorphic DNA markers on rat chromosome 3.	SCN2A HAO1	2.54e-05	5	56	2	8000136
Pubmed	Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy.	LAMA1 LAMC1	2.54e-05	5	56	2	19416897
Pubmed	Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.	CACNA1C CACNA1D	2.54e-05	5	56	2	31663850
Pubmed	FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest.	CUL7 FBXO2	2.54e-05	5	56	2	21135578
Pubmed	Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.	LAMA1 LAMC1	2.54e-05	5	56	2	10964500
Pubmed	The laminin-nidogen complex is a ligand for a specific splice isoform of the transmembrane protein tyrosine phosphatase LAR.	LAMA1 LAMC1	2.54e-05	5	56	2	9647658
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1C CACNA1D	2.54e-05	5	56	2	11296258
Pubmed	Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections.	LAMA1 LAMC1	2.54e-05	5	56	2	8613743
Pubmed	Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.	LAMA1 LAMC1	2.54e-05	5	56	2	9719032
Pubmed	Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality.	LAMA1 LAMC1	2.54e-05	5	56	2	7544312
Pubmed	Laminin-10 is crucial for hair morphogenesis.	LAMA1 LAMC1	2.54e-05	5	56	2	12743034
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1C CACNA1D	2.54e-05	5	56	2	15451373
Pubmed	Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart.	LAMA1 LAMC1	2.54e-05	5	56	2	7851641
Pubmed	Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.	LAMA1 LAMC1	2.54e-05	5	56	2	8719886
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	UBA1 MYH14 TLN1 CAPG LAMC1 ARPC5L SMC2 TBC1D21 DYNC1H1	3.30e-05	1016	56	9	19056867
Pubmed	Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.	LAMA1 LAMC1	3.80e-05	6	56	2	1678389
Pubmed	Voltage-gated calcium channels in developing GnRH-1 neuronal system in the mouse.	CACNA1C CACNA1D	3.80e-05	6	56	2	16029198
Pubmed	Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.	LAMA1 LAMC1	3.80e-05	6	56	2	23948589
Pubmed	Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.	LAMA1 LAMC1	3.80e-05	6	56	2	19118221
Pubmed	Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.	CACNA1C CACNA1D	3.80e-05	6	56	2	21224388
Pubmed	Entactin: structure and function.	LAMA1 LAMC1	3.80e-05	6	56	2	2119632
Pubmed	Laminin is the ECM niche for trophoblast stem cells.	LAMA1 LAMC1	3.80e-05	6	56	2	31937556
Pubmed	Expression and localization of laminin-5 subunits in the mouse incisor.	LAMA1 LAMC1	3.80e-05	6	56	2	9506922
Pubmed	Expression and role of laminin-1 in mouse pancreatic organogenesis.	LAMA1 LAMC1	3.80e-05	6	56	2	10866045
Pubmed	L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins.	CACNA1C CACNA1D	3.80e-05	6	56	2	23734214
Pubmed	Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.	LAMA1 LAMC1	3.80e-05	6	56	2	26555376
Pubmed	A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region.	BICD2 DYNC1H1	3.80e-05	6	56	2	25272277
Pubmed	Effect of basement membrane entactin on epidermal cell attachment and growth.	LAMA1 LAMC1	3.80e-05	6	56	2	3794389
Pubmed	Laminin regulates PDGFRβ(+) cell stemness and muscle development.	LAMA1 LAMC1	3.80e-05	6	56	2	27138650
Pubmed	Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes.	BICD2 DYNC1H1	3.80e-05	6	56	2	11483508
Pubmed	Laminin-nidogen complex. Extraction with chelating agents and structural characterization.	LAMA1 LAMC1	3.80e-05	6	56	2	3109910
Pubmed	A family of mammalian F-box proteins.	FBXL8 CUL7 FBXO2	4.34e-05	42	56	3	10531037
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA1 LAMC1	5.32e-05	7	56	2	14557481
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1D	5.32e-05	7	56	2	12900400
Pubmed	Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice.	LAMA1 LAMC1	5.32e-05	7	56	2	9390664
GeneFamily	Myosin heavy chains	MYH4 MYH14 MYH16	2.98e-06	15	35	3	1098
GeneFamily	Laminin subunits	LAMA1 LAMC1	2.37e-04	12	35	2	626
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1D	1.15e-03	26	35	2	253
Coexpression	GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_UP	CACNA1C KANSL1 RSPH4A JAKMIP3 KIF13A DYNC1H1	3.89e-06	200	55	6	M7437
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D MAGED1 PEG3 ARFGEF1 DYNC1H1	4.64e-06	195	56	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D MAGED1 PEG3 ARFGEF1 DYNC1H1	4.64e-06	195	56	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D MICAL2 SCN2A PEG3	5.00e-06	198	56	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D MICAL2 SCN2A PEG3	5.00e-06	198	56	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RSPH4A MYH14 MICAL2 FBXO2	4.90e-05	160	56	4	028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RSPH4A MYH14 MICAL2 FBXO2	4.90e-05	160	56	4	1f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCell	Control\|World / group, cell type (main and fine annotations)	MYH14 MICAL2 NCKAP5 AGBL1	5.92e-05	168	56	4	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2_Pvalb.Pvalb-Megf11_(Fast-spiking_interneuron,_Pvalb+)\|Striatum / BrainAtlas - Mouse McCarroll V32	MYH4 BECN2 HAO1	6.56e-05	62	56	3	4a2ef605ed5368f7761199fa1fdf3c2da447fc2e
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2_Pvalb.Pvalb-Megf11_(Fast-spiking_interneuron,_Pvalb+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	MYH4 BECN2 HAO1	6.56e-05	62	56	3	2bfa6c957ed4bdf5087a7b233b7ba9eb49d2ae19
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VGF MICAL2 JAKMIP3 FBXO2	6.94e-05	175	56	4	19eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSPH4A MICAL2 KANK3 MPP7	7.41e-05	178	56	4	4ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSPH4A MICAL2 KANK3 MPP7	7.41e-05	178	56	4	c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSPH4A MICAL2 KANK3 MPP7	7.57e-05	179	56	4	abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSPH4A MICAL2 KANK3 MPP7	7.57e-05	179	56	4	0b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	7.57e-05	179	56	4	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	7.57e-05	179	56	4	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	E18.5-samps\|World / Age Group, Lineage, Cell class and subclass	MAGED1 NCKAP5 PIAS1 MPP7	8.07e-05	182	56	4	9649f15858d1ede73e068afc59df3ac367b49687
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	8.60e-05	185	56	4	3be9e05b929ac4d956b1d53284072f668a6c1959
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-lymphatic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	8.60e-05	185	56	4	c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	8.78e-05	186	56	4	5d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	8.78e-05	186	56	4	1da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CACNA1C MICAL2 KIF13A MPP7	9.15e-05	188	56	4	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	CACNA1D SHROOM1 AGBL1 MPP7	9.15e-05	188	56	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH14 MICAL2 AGBL1 MPP7	9.53e-05	190	56	4	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	wk_08-11-Endothelial-Lymph_endothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RSPH4A MICAL2 KANK3 MPP7	9.53e-05	190	56	4	d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	MYH14 MICAL2 AGBL1 MPP7	9.73e-05	191	56	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSPH4A MICAL2 KANK3 MPP7	9.92e-05	192	56	4	fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	MYH14 MICAL2 AGBL1 MPP7	9.92e-05	192	56	4	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSPH4A MICAL2 KANK3 MPP7	9.92e-05	192	56	4	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	MYH14 MICAL2 AGBL1 MPP7	9.92e-05	192	56	4	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	CACNA1C CACNA1D KANK3 NCKAP5	1.01e-04	193	56	4	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C MICAL2 TTC39C SCN2A	1.05e-04	195	56	4	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D MICAL2 SCN2A	1.07e-04	196	56	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 CACNA1C MYH14 PEG3	1.07e-04	196	56	4	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BICD2 CACNA1C MYH14 PEG3	1.07e-04	196	56	4	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D MICAL2 SCN2A	1.12e-04	198	56	4	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C MICAL2 SCN2A PEG3	1.12e-04	198	56	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	wk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	VGF MICAL2 PEG3 LAMA1	1.12e-04	198	56	4	84697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCell	wk_08-11-Epithelial-Distal_epithelial_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	VGF MICAL2 PEG3 LAMA1	1.12e-04	198	56	4	eda85a592527992b51a00f288cff0c3239c47e6f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D SCN2A PEG3	1.12e-04	198	56	4	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH14 MICAL2 AGBL1 MPP7	1.14e-04	199	56	4	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH14 MICAL2 AGBL1 MPP7	1.14e-04	199	56	4	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH14 MICAL2 AGBL1 MPP7	1.14e-04	199	56	4	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYH14 MICAL2 AGBL1 MPP7	1.14e-04	199	56	4	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CACNA1C CACNA1D MICAL2 SCN2A	1.16e-04	200	56	4	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	lung-Type_I_Pneumocytes\|lung / shred on tissue and cell subclass	KANSL1 KANK3 PIAS1	1.51e-04	82	56	3	6023212a51f8b3e05e6c3dcf4e8fbf53ba696fb2
Drug	Cefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A	VGF TLN1 PEG3 CUL7 HCFC1 PSD4	6.32e-06	193	54	6	4245_DN
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D	1.89e-05	4	53	2	DOID:0060173 (implicated_via_orthology)
Disease	corpus callosum volume measurement	ENO4 TTC39C TLN1 LAMC1	3.20e-05	100	53	4	EFO_0010299
Disease	Manic Disorder	CACNA1C CACNA1D SCN2A	2.87e-04	71	53	3	C0024713
Disease	MMR-related febrile seizures	SCN2A AGBL1	3.27e-04	15	53	2	EFO_0006519
Disease	N-acetylmethionine measurement	ALMS1 MICAL2	3.27e-04	15	53	2	EFO_0021427
Disease	Manic	CACNA1C CACNA1D SCN2A	3.78e-04	78	53	3	C0338831
Disease	Depression, Bipolar	CACNA1C CACNA1D SCN2A	3.93e-04	79	53	3	C0005587
Disease	Arthrogryposis	BICD2 DYNC1H1	6.50e-04	21	53	2	C0003886
Disease	Deafness	CACNA1D RSPH4A	9.25e-04	25	53	2	C0011053
Disease	age at first birth measurement	VWC2 SCN2A TBC1D21	1.32e-03	120	53	3	EFO_0009101
Disease	alcohol consumption measurement	CACNA1C CACNA1D KANSL1 ALMS1 NCKAP5 MYH16 JAKMIP3 AGBL1	1.58e-03	1242	53	8	EFO_0007878
Disease	neuroimaging measurement, brain volume measurement	KANSL1 PROSER3 LAMC1 NCKAP5	1.74e-03	286	53	4	EFO_0004346, EFO_0006930

Protein segments in the cluster

Peptide	Gene	Start	Entry
SDDAAEPNNDAEALV	BICD2	286	Q8TD16
NDGAALAELEEQAAS	AKAP4	716	Q5JQC9
AENLAAAQRDAVDFD	ARFGEF1	1646	Q9Y6D6
EEEAAAAAAANVDDV	ALMS1	26	Q8TCU4
EDAFQRVAATANDDA	ADGRG7	216	Q96K78
QAATLLSAEEDALDQ	AGBL1	1056	Q96MI9
NKFVDEQEEAAAAAA	ARPC5L	21	Q9BPX5
AAQAAATEEAQALAI	HCFC1	1621	P51610
DEALDALDAAAAEAE	MAGED1	671	Q9Y5V3
ALDAAAAEAEARAEA	MAGED1	676	Q9Y5V3
DIADLNSVNIADLSD	KIAA1109	3486	Q2LD37
RPEDQQEEEAAAAAA	FBXO2	31	Q9UK22
QEEEAAAAAAYLDEL	FBXO2	36	Q9UK22
REAQAALAEAQEDLE	MYH14	1131	Q7Z406
LLDAQAQAKDSEDAA	CUL7	591	Q14999
ANDEETLADNIAAFS	HAO1	31	Q9UJM8
GAAALADDLAEELQN	MPP7	71	Q5T2T1
NEEIEDLSDAAFAAL	KANSL1	906	Q7Z3B3
EALAALQAANEDLRA	JAKMIP3	16	Q5VZ66
EDNDEALAEILQAND	GGA1	271	Q9UJY5
DEAAAAAAAAAQEVE	PEG3	1361	Q9GZU2
QEEEARQAAAASAAE	PIPSL	716	A2A3N6
AAAAAAISDDQIDIA	PASD1	231	Q8IV76
AEEAEAAAAAAEAAA	FAM9A	191	Q8IZU1
AADLQAAQAEAAELD	BECN2	191	A8MW95
AAFQSLLDAQADEAV	COMMD3	31	Q9UBI1
NVFLAIAVDNLADAE	CACNA1C	746	Q13936
AASAELNAALEELAA	FBXL8	311	Q96CD0
NEEAEKAAEALEAAA	ENO4	586	A6NNW6
LFDAADANAIEEVNL	DYNC1H1	511	Q14204
ALAIALEAEQDEVAA	KANK3	766	Q6NY19
EQQTADQLLARADAA	LAMC1	1331	P11047
EEDLTADKANAQAAA	CAPG	236	P40121
AVDNLADAESLNTAQ	CACNA1D	751	Q01668
DAAVAEALAALEAAT	C4orf19	291	Q8IY42
DSLNEDDAVENNQLA	MICAL2	566	O94851
LFLDLNADDLSANEQ	KIF13A	1176	Q9H1H9
AAQKEADLAAQEEAA	MRPL11	176	Q9Y3B7
AAQEAVLLAAENEES	RSPH4A	691	Q5TD94
QAAAQEERLADLASD	VGF	316	O15240
NNLIDLDADELISAA	TBC1D21	301	Q8IYX1
ALEAENSALALENEN	NCKAP5	191	O14513
LIDAAAAQTDAVQDA	LAMA1	1816	P25391
ENCLDAAADDLLDLQ	PSD4	931	Q8NDX1
YALAAEAEAAAQAAE	SHROOM1	116	Q2M3G4
LQLQVQAEADALADA	MYH4	891	Q9Y623
AQAALLLQAAEDSDG	PROSER3	396	Q2NL68
LAAAAAAVSDDQDLL	PIAS1	561	O75925
DLLNNVASDEANLEA	CLUAP1	201	Q96AJ1
DTPQAEALAAAAQDA	VWC2	116	Q2TAL6
ENELLGAAAAIEAAA	TLN1	2306	Q9Y490
QQEEAQAAAAAASAE	SCN2A	456	Q99250
ALKDVELDFNNVAAD	TTC41P	301	Q6P2S7
NEEDAAELVALAQAV	UBA1	351	P22314
ALQEASNKDAEALAA	SMC2	361	O95347
QEAEEAAETAQARAA	MYH16	561	Q9H6N6
FRSAEAAAAQAEEDL	TOR4A	326	Q9NXH8
INLNDLQFAADAEVS	XNDC1N	201	Q6ZNB5
QEEEDLALAQALSAS	ZFAND2B	221	Q8WV99
DSDAAAAAAAPLQDA	TTC39C	16	Q8N584