Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSNAP receptor activity

VAMP1 VAMP2 VAMP7

1.36e-0539243GO:0005484
GeneOntologyMolecularFunctionsyntaxin binding

VAMP1 VAMP2 VAMP7

1.51e-0487243GO:0019905
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GPR89A GPR89B RYR1 PIEZO2 TRPC7

1.86e-04459245GO:0005216
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

GPR89A GPR89B

1.86e-0417242GO:0008308
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC39A3 GPR89A GPR89B RYR1 PIEZO2 TRPC7

2.80e-04793246GO:0015075
GeneOntologyMolecularFunctionchannel activity

GPR89A GPR89B RYR1 PIEZO2 TRPC7

3.46e-04525245GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GPR89A GPR89B RYR1 PIEZO2 TRPC7

3.49e-04526245GO:0022803
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC39A3 GPR89A GPR89B DISP2 RYR1 PIEZO2 TRPC7

3.51e-041180247GO:0022857
GeneOntologyMolecularFunctionSNARE binding

VAMP1 VAMP2 VAMP7

5.63e-04136243GO:0000149
GeneOntologyMolecularFunctiontransporter activity

SLC39A3 GPR89A GPR89B DISP2 RYR1 PIEZO2 TRPC7

6.00e-041289247GO:0005215
GeneOntologyMolecularFunctiongated channel activity

GPR89A GPR89B RYR1 PIEZO2

6.27e-04334244GO:0022836
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

GPR89A GPR89B RYR1

1.31e-03182243GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

GPR89A GPR89B RYR1

1.35e-03184243GO:0022832
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GPR89A GPR89B

6.75e-03103242GO:0005253
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC39A3 RYR1 PIEZO2 TRPC7

7.58e-03664244GO:0008324
GeneOntologyMolecularFunctionmonoatomic cation channel activity

RYR1 PIEZO2 TRPC7

7.78e-03343243GO:0005261
GeneOntologyBiologicalProcessnatural killer cell degranulation

UNC13D VAMP2 VAMP7

1.12e-0618243GO:0043320
GeneOntologyBiologicalProcessSNARE complex assembly

VAMP1 VAMP2 VAMP7

3.54e-0626243GO:0035493
GeneOntologyBiologicalProcessexocytic process

UNC13D VAMP1 VAMP2 VAMP7

6.71e-06107244GO:0140029
GeneOntologyBiologicalProcessnatural killer cell activation involved in immune response

UNC13D VAMP2 VAMP7

1.54e-0542243GO:0002323
GeneOntologyBiologicalProcessregulation of histamine secretion by mast cell

VAMP2 VAMP7

3.62e-058242GO:1903593
GeneOntologyBiologicalProcesseosinophil activation involved in immune response

VAMP2 VAMP7

4.65e-059242GO:0002278
GeneOntologyBiologicalProcesseosinophil degranulation

VAMP2 VAMP7

4.65e-059242GO:0043308
GeneOntologyBiologicalProcesseosinophil activation

VAMP2 VAMP7

5.81e-0510242GO:0043307
GeneOntologyBiologicalProcesseosinophil mediated immunity

VAMP2 VAMP7

5.81e-0510242GO:0002447
GeneOntologyBiologicalProcessmast cell degranulation

UNC13D VAMP2 VAMP7

8.50e-0574243GO:0043303
GeneOntologyBiologicalProcessmast cell mediated immunity

UNC13D VAMP2 VAMP7

9.20e-0576243GO:0002448
GeneOntologyBiologicalProcessmast cell activation involved in immune response

UNC13D VAMP2 VAMP7

9.94e-0578243GO:0002279
GeneOntologyBiologicalProcesscalcium-ion regulated exocytosis

UNC13D VAMP2 VAMP7

1.15e-0482243GO:0017156
GeneOntologyBiologicalProcesshistamine production involved in inflammatory response

VAMP2 VAMP7

1.54e-0416242GO:0002349
GeneOntologyBiologicalProcessneutrophil degranulation

VAMP2 VAMP7

1.54e-0416242GO:0043312
GeneOntologyBiologicalProcesshistamine secretion involved in inflammatory response

VAMP2 VAMP7

1.54e-0416242GO:0002441
GeneOntologyBiologicalProcesshistamine secretion by mast cell

VAMP2 VAMP7

1.54e-0416242GO:0002553
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC39A3 GPR89A GPR89B RYR1 PIEZO2 TRPC7 VAMP2

2.03e-041115247GO:0034220
GeneOntologyBiologicalProcessmast cell activation

UNC13D VAMP2 VAMP7

2.14e-04101243GO:0045576
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity

UNC13D VAMP2 VAMP7

2.40e-04105243GO:0042267
GeneOntologyBiologicalProcesslysosome localization

UNC13D VAMP2 VAMP7

2.54e-04107243GO:0032418
GeneOntologyBiologicalProcessvacuolar localization

UNC13D VAMP2 VAMP7

2.54e-04107243GO:1990849
GeneOntologyBiologicalProcessleukocyte degranulation

UNC13D VAMP2 VAMP7

2.61e-04108243GO:0043299
GeneOntologyBiologicalProcessnatural killer cell mediated immunity

UNC13D VAMP2 VAMP7

2.68e-04109243GO:0002228
GeneOntologyBiologicalProcesshistamine secretion

VAMP2 VAMP7

2.96e-0422242GO:0001821
GeneOntologyBiologicalProcessneutrophil activation involved in immune response

VAMP2 VAMP7

3.23e-0423242GO:0002283
GeneOntologyBiologicalProcessregulated exocytosis

UNC13D VAMP1 VAMP2 VAMP7

3.30e-04291244GO:0045055
GeneOntologyBiologicalProcesshistamine transport

VAMP2 VAMP7

3.83e-0425242GO:0051608
GeneOntologyBiologicalProcessnatural killer cell activation

UNC13D VAMP2 VAMP7

3.91e-04124243GO:0030101
GeneOntologyBiologicalProcessmyeloid cell activation involved in immune response

UNC13D VAMP2 VAMP7

4.01e-04125243GO:0002275
GeneOntologyBiologicalProcessvesicle fusion

VAMP1 VAMP2 VAMP7

5.82e-04142243GO:0006906
GeneOntologyBiologicalProcessorganelle membrane fusion

VAMP1 VAMP2 VAMP7

6.06e-04144243GO:0090174
GeneOntologyBiologicalProcessmyeloid leukocyte mediated immunity

UNC13D VAMP2 VAMP7

6.56e-04148243GO:0002444
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC39A3 GPR89A GPR89B RYR1 PIEZO2 TRPC7 VAMP2

7.25e-041374247GO:0006811
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

UNC13D VAMP2 VAMP7

8.99e-04165243GO:1903305
GeneOntologyBiologicalProcessregulation of mast cell degranulation

UNC13D VAMP7

1.09e-0342242GO:0043304
GeneOntologyBiologicalProcessGolgi to plasma membrane protein transport

VAMP2 VAMP7

1.25e-0345242GO:0043001
GeneOntologyBiologicalProcessvesicle organization

SRGN VAMP1 VAMP2 VAMP7

1.25e-03415244GO:0016050
GeneOntologyBiologicalProcessleukocyte mediated cytotoxicity

UNC13D VAMP2 VAMP7

1.29e-03187243GO:0001909
GeneOntologyBiologicalProcessorganelle fusion

VAMP1 VAMP2 VAMP7

1.35e-03190243GO:0048284
GeneOntologyBiologicalProcessneutrophil mediated immunity

VAMP2 VAMP7

1.42e-0348242GO:0002446
GeneOntologyBiologicalProcessexocytosis

UNC13D VAMP1 VAMP2 VAMP7

1.47e-03434244GO:0006887
GeneOntologyBiologicalProcessneutrophil activation

VAMP2 VAMP7

1.48e-0349242GO:0042119
GeneOntologyBiologicalProcessmembrane fusion

VAMP1 VAMP2 VAMP7

1.82e-03211243GO:0061025
GeneOntologyBiologicalProcessgranulocyte activation

VAMP2 VAMP7

2.06e-0358242GO:0036230
GeneOntologyBiologicalProcessintracellular pH reduction

GPR89A GPR89B

2.06e-0358242GO:0051452
GeneOntologyBiologicalProcessregulation of exocytosis

UNC13D VAMP2 VAMP7

2.42e-03233243GO:0017157
GeneOntologyBiologicalProcessregulation of leukocyte degranulation

UNC13D VAMP7

2.43e-0363242GO:0043300
GeneOntologyBiologicalProcesspositive regulation of regulated secretory pathway

UNC13D VAMP7

2.66e-0366242GO:1903307
GeneOntologyBiologicalProcesslymphocyte activation involved in immune response

UNC13D VAMP2 VAMP7

2.98e-03251243GO:0002285
GeneOntologyBiologicalProcessGolgi to plasma membrane transport

VAMP2 VAMP7

2.99e-0370242GO:0006893
GeneOntologyBiologicalProcessestablishment of protein localization to plasma membrane

VAMP2 VAMP7

3.51e-0376242GO:0061951
GeneOntologyBiologicalProcessregulation of myeloid leukocyte mediated immunity

UNC13D VAMP7

3.97e-0381242GO:0002886
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC39A3 RYR1 PIEZO2 TRPC7 VAMP2

4.05e-03942245GO:0098655
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

RYR1 TRPC7

4.27e-0384242GO:0051480
GeneOntologyBiologicalProcesslymphocyte activation

GPR89A GPR89B UNC13D VAMP2 VAMP7

4.71e-03976245GO:0046649
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

GPR89A GPR89B RYR1 TRPC7

5.06e-03611244GO:0030003
GeneOntologyBiologicalProcesscell killing

UNC13D VAMP2 VAMP7

5.24e-03307243GO:0001906
GeneOntologyBiologicalProcessregulation of intracellular pH

GPR89A GPR89B

5.31e-0394242GO:0051453
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

GPR89A GPR89B RYR1 TRPC7

5.38e-03622244GO:0006873
GeneOntologyBiologicalProcessmyeloid leukocyte activation

UNC13D VAMP2 VAMP7

5.88e-03320243GO:0002274
GeneOntologyBiologicalProcessregulation of cellular pH

GPR89A GPR89B

6.11e-03101242GO:0030641
GeneOntologyBiologicalProcesssignal release

AIMP1 VAMP1 VAMP2 VAMP7

6.39e-03653244GO:0023061
GeneOntologyCellularComponentSNARE complex

VAMP1 VAMP2 VAMP7

2.67e-0551243GO:0031201
GeneOntologyCellularComponentmonoatomic ion channel complex

GPR89A GPR89B RYR1 TRPC7 VAMP2

6.03e-05378245GO:0034702
GeneOntologyCellularComponentGolgi apparatus subcompartment

GPR89A MS4A6A GPR89B VAMP2 VAMP7

1.27e-04443245GO:0098791
GeneOntologyCellularComponenttransmembrane transporter complex

GPR89A GPR89B RYR1 TRPC7 VAMP2

2.76e-04523245GO:1902495
GeneOntologyCellularComponenttransporter complex

GPR89A GPR89B RYR1 TRPC7 VAMP2

3.48e-04550245GO:1990351
GeneOntologyCellularComponentexocytic vesicle

UNC13D VAMP1 VAMP2 VAMP7

4.50e-04320244GO:0070382
GeneOntologyCellularComponentzymogen granule

SRGN VAMP2

6.14e-0432242GO:0042588
GeneOntologyCellularComponentazurophil granule

UNC13D VAMP1 VAMP7

7.91e-04160243GO:0042582
GeneOntologyCellularComponentprimary lysosome

UNC13D VAMP1 VAMP7

7.91e-04160243GO:0005766
GeneOntologyCellularComponentexocytic vesicle membrane

VAMP1 VAMP2 VAMP7

1.09e-03179243GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

VAMP1 VAMP2 VAMP7

1.09e-03179243GO:0030672
GeneOntologyCellularComponentmembrane protein complex

GPR89A GPR89B RYR1 TRPC7 VAMP1 VAMP2 VAMP7

1.12e-031498247GO:0098796
GeneOntologyCellularComponentazurophil granule membrane

VAMP1 VAMP7

2.08e-0359242GO:0035577
GeneOntologyCellularComponentGolgi-associated vesicle membrane

GPR89A GPR89B

2.22e-0361242GO:0030660
GeneOntologyCellularComponentcation channel complex

RYR1 TRPC7 VAMP2

2.38e-03235243GO:0034703
GeneOntologyCellularComponentclathrin-coated vesicle

UNC13D VAMP2 VAMP7

2.44e-03237243GO:0030136
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

SLC39A3 VAMP7

2.67e-0367242GO:0098686
GeneOntologyCellularComponenttransport vesicle

UNC13D VAMP1 VAMP2 VAMP7

2.69e-03519244GO:0030133
GeneOntologyCellularComponentvacuole

UNC13D SRGN VAMP1 VAMP2 VAMP7

3.34e-03913245GO:0005773
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

VAMP2 VAMP7

3.69e-0379242GO:0030669
GeneOntologyCellularComponenttransport vesicle membrane

VAMP1 VAMP2 VAMP7

4.44e-03293243GO:0030658
GeneOntologyCellularComponentsynaptic vesicle

VAMP1 VAMP2 VAMP7

4.74e-03300243GO:0008021
GeneOntologyCellularComponenttrans-Golgi network

MS4A6A VAMP2 VAMP7

5.01e-03306243GO:0005802
GeneOntologyCellularComponentplatelet alpha granule

SRGN VAMP7

5.07e-0393242GO:0031091
GeneOntologyCellularComponentGolgi cisterna membrane

GPR89A GPR89B

5.18e-0394242GO:0032580
GeneOntologyCellularComponentsecretory granule

UNC13D SRGN VAMP1 VAMP2 VAMP7

5.23e-031014245GO:0030141
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

VAMP2 VAMP7

5.95e-03101242GO:0045334
GeneOntologyCellularComponentsecretory granule membrane

VAMP1 VAMP2 VAMP7

6.12e-03329243GO:0030667
GeneOntologyCellularComponentGolgi-associated vesicle

GPR89A GPR89B

7.52e-03114242GO:0005798
GeneOntologyCellularComponentcoated vesicle

UNC13D VAMP2 VAMP7

7.84e-03360243GO:0030135
GeneOntologyCellularComponentGolgi cisterna

GPR89A GPR89B

1.04e-02135242GO:0031985
GeneOntologyCellularComponentclathrin-coated vesicle membrane

VAMP2 VAMP7

1.22e-02147242GO:0030665
GeneOntologyCellularComponentsecretory vesicle

UNC13D SRGN VAMP1 VAMP2 VAMP7

1.23e-021246245GO:0099503
GeneOntologyCellularComponentlysosome

UNC13D SRGN VAMP1 VAMP7

1.29e-02811244GO:0005764
GeneOntologyCellularComponentlytic vacuole

UNC13D SRGN VAMP1 VAMP7

1.29e-02811244GO:0000323
GeneOntologyCellularComponentcytoplasmic vesicle membrane

GPR89A GPR89B VAMP1 VAMP2 VAMP7

1.49e-021307245GO:0030659
GeneOntologyCellularComponentvesicle membrane

GPR89A GPR89B VAMP1 VAMP2 VAMP7

1.57e-021325245GO:0012506
GeneOntologyCellularComponentGolgi stack

GPR89A GPR89B

1.63e-02171242GO:0005795
DomainSYNAPTOBREVIN

VAMP1 VAMP2 VAMP7

9.10e-088233PS00417
Domain-

VAMP1 VAMP2 VAMP7

9.10e-0882331.10.3840.10
DomainSynaptobrevin

VAMP1 VAMP2 VAMP7

2.67e-0711233PF00957
DomainV_SNARE

VAMP1 VAMP2 VAMP7

3.56e-0712233PS50892
DomainSynaptobrevin

VAMP1 VAMP2 VAMP7

4.63e-0713233IPR001388
DomainSynaptobrevin/VAMP

VAMP1 VAMP2

2.17e-056232IPR016444
DomainIon_trans_dom

RYR1 TRPC7

8.59e-03114232IPR005821
DomainIon_trans

RYR1 TRPC7

8.59e-03114232PF00520
Domain-

UNC13D SYDE2

1.41e-021482322.60.40.150
DomainC2_dom

UNC13D SYDE2

1.72e-02164232IPR000008
PathwayKEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT

VAMP1 VAMP2 VAMP7

1.70e-0538193M17857
PathwayREACTOME_TOXICITY_OF_BOTULINUM_TOXIN_TYPE_D_BOTD

VAMP1 VAMP2

1.72e-055192M27427
PathwayREACTOME_NEUROTOXICITY_OF_CLOSTRIDIUM_TOXINS

VAMP1 VAMP2

7.70e-0510192M27018
PathwayREACTOME_BACTERIAL_INFECTION_PATHWAYS

RNF213 VAMP1 VAMP2

1.12e-0471193M48033
PathwayWP_GPCRS_ORPHAN

GPR89A GPR89B

2.90e-0419192MM15991
PathwayREACTOME_UPTAKE_AND_ACTIONS_OF_BACTERIAL_TOXINS

VAMP1 VAMP2

6.84e-0429192M27431
PathwayREACTOME_LYSOSOME_VESICLE_BIOGENESIS

VAMP2 VAMP7

9.97e-0435192M2881
Pubmed

Ablation of All Synaptobrevin vSNAREs Blocks Evoked But Not Spontaneous Neurotransmitter Release at Neuromuscular Synapses.

VAMP1 VAMP2 VAMP7

1.01e-08724331160536
Pubmed

v-SNAREs control exocytosis of vesicles from priming to fusion.

VAMP1 VAMP2 VAMP7

3.45e-081024315920476
Pubmed

Synaptobrevin 1 mediates vesicle priming and evoked release in a subpopulation of hippocampal neurons.

VAMP1 VAMP2

4.56e-07224224944211
Pubmed

Tetanus insensitive VAMP2 differentially restores synaptic and dense core vesicle fusion in tetanus neurotoxin treated neurons.

VAMP1 VAMP2

4.56e-07224232616842
Pubmed

Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line.

VAMP2 VAMP7

4.56e-07224218042464
Pubmed

GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.

GPR89A GPR89B

4.56e-07224218794847
Pubmed

Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.

VAMP1 VAMP2

4.56e-0722421976629
Pubmed

GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.

GPR89A GPR89B

4.56e-07224222572823
Pubmed

A splice-isoform of vesicle-associated membrane protein-1 (VAMP-1) contains a mitochondrial targeting signal.

VAMP1 VAMP2

4.56e-0722429658161
Pubmed

Modeling the role of mid-wavelength cones in circadian responses to light.

OPN4 THRB

4.56e-07224217329208
Pubmed

Identification of a human homologue of the vesicle-associated membrane protein (VAMP)-associated protein of 33 kDa (VAP-33): a broadly expressed protein that binds to VAMP.

VAMP1 VAMP2

1.37e-0632429657962
Pubmed

Role of VAMP-2, VAMP-7, and VAMP-8 in constitutive exocytosis from HSY cells.

VAMP2 VAMP7

1.37e-06324216195891
Pubmed

Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.

GPR89A GPR89B

1.37e-06324232220963
Pubmed

The Retinal Basis of Light Aversion in Neonatal Mice.

OPN4 TRPC7

1.37e-06324235396331
Pubmed

Exocytosis at the hair cell ribbon synapse apparently operates without neuronal SNARE proteins.

VAMP1 VAMP2

1.37e-06324221378973
Pubmed

Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion.

UNC13D VAMP2

1.37e-06324222508512
Pubmed

SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.

GPR89A UNC13D DISP2 RYR1 VAMP1 THRB VAMP2

2.00e-0691524732393512
Pubmed

Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.

VAMP1 VAMP2

2.74e-0642428760387
Pubmed

Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice.

GPR89A GPR89B

2.74e-06424231118204
Pubmed

Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7.

UNC13D VAMP7

2.74e-06424222589474
Pubmed

Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31.

VAMP1 VAMP2

2.74e-0642429396746
Pubmed

The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells.

VAMP1 VAMP2

2.74e-0642428707843
Pubmed

Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.

OPN4 TRPC7

2.74e-06424230017393
Pubmed

A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils.

VAMP2 VAMP7

4.56e-06524216677249
Pubmed

Munc 18a binding to syntaxin 1A and 1B isoforms defines its localization at the plasma membrane and blocks SNARE assembly in a three-hybrid system assay.

VAMP1 VAMP2

4.56e-06524212093152
Pubmed

The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions.

VAMP2 VAMP7

4.56e-06524215610015
Pubmed

Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes.

VAMP2 VAMP7

4.56e-06524218227281
Pubmed

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.

OPN4 TRPC7

4.56e-06524221261756
Pubmed

Rods contribute to the light-induced phase shift of the retinal clock in mammals.

OPN4 THRB

4.56e-06524230822304
Pubmed

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins.

VAMP1 VAMP2

4.56e-0652429920726
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

GPR89A RNF213 UGGT2 TLCD4 FASTKD1 VAMP2 VAMP7

5.29e-06106124733845483
Pubmed

Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs.

VAMP2 VAMP7

6.83e-06624211786915
Pubmed

Embryonic and postnatal development of the serotonergic raphe system and its target regions in 5-HT1A receptor deletion or overexpressing mouse mutants.

VAMP1 VAMP2

6.83e-06624217543467
Pubmed

Syntaxin 1 is required for DCC/Netrin-1-dependent chemoattraction of migrating neurons from the lower rhombic lip.

VAMP2 VAMP7

6.83e-06624222946563
Pubmed

Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1.

VAMP2 VAMP7

6.83e-06624237723322
Pubmed

Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.

GPR89A GPR89B

9.56e-06724216015370
Pubmed

Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact.

PIEZO2 OPN4

9.56e-06724238733989
Pubmed

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells.

VAMP2 VAMP7

9.56e-06724218253931
Pubmed

Requirement for distinct vesicle-associated membrane proteins in insulin- and AMP-activated protein kinase (AMPK)-induced translocation of GLUT4 and CD36 in cultured cardiomyocytes.

VAMP2 VAMP7

9.56e-06724220582536
Pubmed

Fusogenic pairings of vesicle-associated membrane proteins (VAMPs) and plasma membrane t-SNAREs--VAMP5 as the exception.

VAMP1 VAMP7

9.56e-06724221151919
Pubmed

Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.

OPN4 TRPC7

9.56e-06724238109525
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

GPR89A GPR89B RNF213 RYR1

1.20e-0520824433230847
Pubmed

The vesicular SNARE Synaptobrevin is required for Semaphorin 3A axonal repulsion.

VAMP2 VAMP7

1.27e-05824222213797
Pubmed

Differential distributions of the Ca2+ -dependent activator protein for secretion family proteins (CAPS2 and CAPS1) in the mouse brain.

VAMP1 VAMP2

1.27e-05824216506193
Pubmed

A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones.

VAMP2 VAMP7

1.27e-05824221994363
Pubmed

A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function.

VAMP2 VAMP7

1.64e-05924211101518
Pubmed

Syntaxin 7 complexes with mouse Vps10p tail interactor 1b, syntaxin 6, vesicle-associated membrane protein (VAMP)8, and VAMP7 in b16 melanoma cells.

VAMP2 VAMP7

1.64e-05924211278762
Pubmed

SNAREs and SNARE regulators in membrane fusion and exocytosis.

VAMP1 VAMP2

2.05e-051024210379359
Pubmed

A dual mechanism controlling the localization and function of exocytic v-SNAREs.

VAMP2 VAMP7

2.50e-051124212853575
Pubmed

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles.

VAMP2 VAMP7

3.00e-051224219144828
Pubmed

Melanopsin signalling in mammalian iris and retina.

OPN4 TRPC7

3.54e-051324222051675
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

VAMP1 VAMP2

4.77e-051524218227507
Pubmed

The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes.

VAMP2 VAMP7

5.44e-051624227791468
Pubmed

Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.

RYR1 TRPC7

6.17e-051724222411552
Pubmed

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

SYDE2 VAMP2

8.61e-052024223791195
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

OPN4 TRPC7

9.51e-052124230270038
Pubmed

Onecut1 and Onecut2 play critical roles in the development of the mouse retina.

OPN4 THRB

1.59e-042724225313862
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

RYR1 TRPC7

3.16e-043824230786075
Pubmed

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.

OPN4 THRB

4.05e-044324225228773
Pubmed

Identification of APBB1 as a substrate for anaplastic lymphoma kinase.

GPR89A VAMP7

4.24e-044424239115278
Pubmed

Three ways to make a vesicle.

VAMP2 VAMP7

4.24e-044424211252894
Pubmed

Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.

GPR89A GPR89B

4.84e-044724229617656
Pubmed

Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage.

VAMP1 VAMP2

4.84e-044724231235642
InteractionOPALIN interactions

SLC39A3 GPR89A RNF213 FASTKD1 VAMP7

4.14e-06209245int:OPALIN
Cytoband1q21.1

GPR89A GPR89B

4.86e-04622421q21.1
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHGA1 TRPC7

1.05e-02298242chr5q31
CytobandEnsembl 112 genes in cytogenetic band chr17q25

RNF213 UNC13D

1.12e-02307242chr17q25
GeneFamilyVesicle associated membrane proteins

VAMP1 VAMP2 VAMP7

2.41e-08717312
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SACS RYR1

1.23e-02181172694
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000

SACS RNF213 UGGT2 TLCD4 RYR1

4.04e-06219245gudmap_developingGonad_e16.5_ovary_1000_k5
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A RNF213 SRGN RYR1

3.54e-0619724410190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A RNF213 SRGN RYR1

3.68e-061992445ceeed92f831d068ff4bb3994f420002338330e7
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRGN RYR1 VAMP1

7.26e-0515224382a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SACS UGGT2 FASTKD1

7.84e-05156243a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC7 FASTKD1 THRB

8.30e-051592437619d0d49738dd08daf01b42664691a5323aa793
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC7 FASTKD1 THRB

8.30e-051592434000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellControl-APC-like-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

MS4A6A SRGN RYR1

8.46e-05160243463dd624ca5c375b6ff7c269f4ef4b9d74f4b669
ToppCellBAL-Mild-cDC_5|Mild / Compartment, Disease Groups and Clusters

HSF2BP DISP2 RYR1

8.61e-051612437a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCellfacs-Marrow-KLS-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR89A UGGT2 RYR1

9.94e-05169243b798b91567d2f49082e2d8a337169f241c8d2080
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SRGN RYR1 VAMP2

1.05e-04172243c74c1d47b133eb5d0f762a06e421252a76b4672b
ToppCellwk_15-18-Hematologic-Myeloid-Eosinophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC39A3 UNC13D SRGN

1.07e-04173243a85cead231e03945fabbc7762540ad21fe4299df
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

MS4A6A UGGT2 SRGN

1.08e-041742431e289b26e2c29dbad15b712a999b96c391a26129
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A SRGN RYR1

1.18e-04179243716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC39A3 SACS THRB

1.18e-04179243adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A SRGN RYR1

1.22e-04181243090e89b506d945e123e647d08947e9649a65ce7c
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 SRGN PIEZO2

1.24e-041822437af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 SRGN PIEZO2

1.24e-04182243e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.26e-04183243a97f052950429245c3231464271e1ba539863bba
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF213 SRGN THRB

1.26e-04183243e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UGGT2 FASTKD1 VAMP1

1.28e-04184243a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UGGT2 FASTKD1 VAMP1

1.28e-04184243081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

UGGT2 FASTKD1 VAMP1

1.28e-0418424345f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

UGGT2 FASTKD1 VAMP1

1.28e-0418424384c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

UGGT2 FASTKD1 VAMP1

1.28e-04184243c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

UGGT2 FASTKD1 VAMP1

1.28e-041842432fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

SLC39A3 PIEZO2 THRB

1.28e-04184243b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UGGT2 FASTKD1 VAMP1

1.28e-04184243d31d4116d1d196633784863781fa45673607a421
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.30e-04185243ab5704b96f1d368911308797d10c7c52766ab134
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.32e-041862436575ec6a626cdea169ffd185d47828dfaa29475d
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.34e-04187243bde6b90955423eab6a91a0abe75d0a95a1f5330a
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.34e-0418724323be50d81f4404a609dea821e1a66d221c0e0615
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.34e-0418724339b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.36e-041882433be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.36e-04188243f4d11d06be46f13adbf36d94bc2bdcd14d0bfa75
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A SRGN RYR1

1.36e-04188243cb091912f9b627a78a8793a37df7f1de839f887f
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.36e-041882438fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.38e-04189243440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.38e-04189243a438c64a893d43f781ede42e1c7b615b74dc76ef
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.38e-0418924331c8bc506ad69f2ed5676bd7e5319bad1075c8d8
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

MS4A6A SRGN RYR1

1.38e-041892432586f4088721c5debec86c2b211b739fd33713eb
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A SRGN RYR1

1.38e-04189243b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.41e-04190243e5625feb21915d4545cfad2659745ef180efcb1f
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.41e-04190243912aa106581d1ed7e147c92f9a367e8e6b04052b
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.41e-04190243081b7bc07b6e5685e8a91b9ae6c1141623723700
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.41e-04190243773c55b9e28c2f77a5eb5f0adb0fa9862fb9611d
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.41e-04190243e0b363f772817cfc6ab425430805c1cddcba23f0
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.43e-0419124324d75b7e1d6fb9d24aa7844f584ee888a449841f
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.43e-04191243c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.43e-0419124309dfad8e1fcaaf94775134796b99e4e3fbb9bf40
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.43e-04191243bce138f067b8962ecef1ddec6511a3f142d81d78
ToppCellNasal_Brush-Immune-Neutrophils|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MS4A6A UNC13D SRGN

1.45e-0419224320a7f7beb01df1c4f915ec2f9b5a9dbcab157187
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.45e-041922437e7383093efaadceadd4d1f900c2d39cd690102e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MS4A6A SRGN VAMP7

1.45e-041922435ea1a8119012eb8bc3100b739a0430377a8ac534
ToppCell18-Distal-Immune-Hematopoietic,_Macrophage|Distal / Age, Tissue, Lineage and Cell class

MS4A6A SRGN RYR1

1.45e-04192243e54577183b09599a3b2bdd532a18ea8f4a6e3524
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.45e-041922434e3deefd30adb7bf1eba294610eed3d077aa9418
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.45e-04192243b204ef6e05170855259b902829a1700094eb9159
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.47e-04193243bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.47e-041932432d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

MS4A6A SRGN RYR1

1.47e-04193243a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.47e-041932432684fa361baaa9dc7a18a39ed11c0759e78e4418
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.47e-04193243374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)|Adult / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.47e-0419324331c0978ba78c9516d498aec0798902e57555e557
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.47e-0419324364d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.49e-04194243ef30baa19b7aa97b61dea916fc2e0f5cf49848d6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.49e-0419424396f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.49e-04194243abce1e824ce2512741c313a5ec336d12f580b093
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.49e-04194243c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.49e-041942436810586080cc893e3270b9c8bee2d95ed78e2893
ToppCellPCW_07-8.5-Hematologic_Myeloid|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.49e-04194243260649f5c4aeaa9cbf5ed5ae5e9f293d75bb0457
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.49e-04194243846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.49e-04194243800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

MS4A6A SRGN THRB

1.49e-04194243ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.49e-04194243fad22d5cf62016cad979e6943e357106d8d2a4b4
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.49e-04194243a062100ea6cd512a108f9036c259e0cd0f458563
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-041952436c354c38ee2965d37152ffdc86ba929ba2049c6a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.52e-0419524391a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.52e-0419524342bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCellPCW_10-12-Hematologic_Myeloid|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-041952436352cd749091cfdbf5cce3c354fa57883cc513e8
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-04195243518cc3baeb7cf2ad068692cbe85fd75be67f1872
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-04195243c707885d092aedbbe14f51f7de4a5911c9214289
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MS4A6A SRGN RYR1

1.52e-04195243312d9625655b38f1a7c2bf8f8bb7b667ebdf9617
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-04195243799992721369357484300fe218aff075154c3148
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor2_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-04195243e8fb552f9ab77b656c27abc66af523b56cd9f9ad
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.52e-041952435f46f9aca1c7f76416e861aa94d24fc1d6266113
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.54e-04196243cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.54e-041962433fd5567ea14193181929134c377e8a38fb4f47fd
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.54e-04196243ce3709adbde7559b40c964888935914f66003247
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MS4A6A RNF213 SRGN

1.54e-04196243e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MS4A6A SRGN RYR1

1.56e-041972431c0024049db2d2c817a7f503de235b9630b24e33
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.56e-041972438af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.56e-041972436ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

MS4A6A RNF213 SRGN

1.56e-04197243e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MS4A6A SRGN VAMP2

1.56e-04197243e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

MS4A6A RNF213 SRGN

1.56e-04197243a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

RYR1 PIEZO2 FASTKD1

1.56e-0419724315b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.56e-04197243d95565652ca318a2298d6918d54ba6367e9560f4
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

RYR1 PIEZO2 FASTKD1

1.56e-04197243a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

MS4A6A RNF213 SRGN

1.59e-04198243ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A6A SRGN RYR1

1.59e-0419824396883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MS4A6A SRGN RYR1

1.59e-041982431d242fbe4ae3628103f6b6f910a7641bb1b75266
DrugBotulinum Toxin Type B

VAMP1 VAMP2

3.19e-063242DB00042
Drugbotulinum toxin type D

VAMP1 VAMP2

6.38e-064242ctd:C096325
DrugrimabotulinumtoxinB

VAMP1 VAMP2

1.06e-055242ctd:C096323
DrugOxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; MCF7; HT_HG-U133A

UGGT2 SRGN VAMP1 VAMP2

5.14e-051982443170_DN
Drug(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A

HSF2BP PCDHGA1 VAMP1 THRB

5.14e-051982444363_UP
DrugEtanidazole [22668-01-5]; Up 200; 18.6uM; MCF7; HT_HG-U133A

HSF2BP RYR1 VAMP1 VAMP2

5.25e-051992446072_UP
Drugp11-13

RYR1 OPN4 VAMP7

6.61e-0575243CID000015759
Diseaseascending aortic diameter

UNC13D DISP2 PIEZO2

1.97e-04140243EFO_0021787

Protein segments in the cluster

PeptideGeneStartEntry
KNLKMMIILGVICAI

VAMP2

91

P63027
MVILLCNLKPAKMRG

AIMP1

206

Q12904
RKLGIILMMVKCVSC

DISP2

1086

A7MBM2
ECKMAKIMLLVILLF

OPN4

291

Q9UHM6
KMNLCVILLILVFMV

GPR89A

76

B7ZAQ6
KMNLCVILLILVFMV

GPR89B

76

P0CG08
IIMAKKKLTEMIPLC

FASTKD1

286

Q53R41
KVIGTIQILCGMMVL

MS4A6A

46

Q9H2W1
VLQIMEKMPLQKLCN

SACS

876

Q9NZJ4
LLQMKLPESVKLQMC

RYR1

1926

P21817
VATLKKMLPIGLNMC

RYR1

3511

P21817
MKIQKKLTGCSRLML

PCDHGA1

1

Q9Y5H4
NIGLMVPLLIQKCIM

SYDE2

826

Q5VT97
LKPGQCTKLKVLMLM

HSF2BP

221

O75031
KMMIMLGAICAIIVV

VAMP1

96

P23763
MVKLLVAKILCMVGV

SLC39A3

1

Q9BRY0
KICMETGKMVLLLNL

RNF213

3091

Q63HN8
MMQKLLKCSRLVLAL

SRGN

1

P10124
QIILLKGCCMEIMSL

THRB

301

P10828
IMKVLGNLVVAMFIK

PIEZO2

671

Q9H5I5
VMWMIKISKGCIKVI

TLCD4

231

Q96MV1
AMCMKNLKLTIIIII

VAMP7

181

P51809
MAQLLVVLGKIINMK

UGGT2

981

Q9NYU1
LLRVLVQMCKMKAFG

UNC13D

431

Q70J99
LIMRIKMCLIKLCKS

TRPC7

721

Q9HCX4