Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2B2 ATP2B3 ATP2B4	1.90e-05	11	99	3	GO:0005388
GeneOntologyMolecularFunction	calmodulin binding	CACNA1C MYH4 PDE1B NOS2 ATP2B2 ATP2B3 ATP2B4 UNC13A	1.91e-05	230	99	8	GO:0005516
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYH4 DHX37 DDX60 KIF21A DNAH2 CHD3 CLPB ATP2B2 ATP2B3 ATP2B4	6.73e-05	441	99	10	GO:0016887
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1C ITPR1 CACNA1H ATP2B2 ATP2B3 ATP2B4	1.06e-04	151	99	6	GO:0015085
GeneOntologyMolecularFunction	actin filament binding	MYH4 CORO2A SPTA1 VILL AFDN FERMT2 FMNL1	1.37e-04	227	99	7	GO:0051015
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1C SLC9A8 CNNM2 SLC39A4 ITPR1 CACNA1H ATP2B2 ATP2B3 ATP2B4	5.06e-04	465	99	9	GO:0046873
GeneOntologyMolecularFunction	actin binding	MYH4 CORO2A SPTA1 VILL SYNE2 AFDN FERMT2 NOS2 FMNL1	6.26e-04	479	99	9	GO:0003779
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP2B2 ATP2B3 ATP2B4	7.50e-04	36	99	3	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP2B2 ATP2B3 ATP2B4	7.50e-04	36	99	3	GO:0015662
GeneOntologyMolecularFunction	ATP-dependent activity	MYH4 DHX37 DDX60 KIF21A DNAH2 CHD3 CLPB ATP2B2 ATP2B3 ATP2B4	9.38e-04	614	99	10	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal protein binding	CACNA1C MYH4 CORO2A SPTA1 KIF21A CKAP5 ARFGEF1 VILL SYNE2 AFDN FERMT2 NOS2 FMNL1 UNC13A	1.03e-03	1099	99	14	GO:0008092
GeneOntologyBiologicalProcess	monoatomic cation homeostasis	CACNA1C SLC9A8 CNNM2 FATE1 GCM2 SLC39A4 EXT2 ITPR1 ERFE TNFSF11 TMTC4 ATP2B2 ATP2B3 ATP2B4 WDR72	1.00e-06	705	97	15	GO:0055080
GeneOntologyBiologicalProcess	monoatomic ion homeostasis	CACNA1C SLC9A8 CNNM2 FATE1 GCM2 SLC39A4 EXT2 ITPR1 ERFE TNFSF11 TMTC4 ATP2B2 ATP2B3 ATP2B4 WDR72	1.24e-06	717	97	15	GO:0050801
GeneOntologyBiologicalProcess	inorganic ion homeostasis	CACNA1C CNNM2 FATE1 GCM2 SLC39A4 EXT2 ITPR1 ERFE TNFSF11 TMTC4 ATP2B2 ATP2B3 ATP2B4	6.87e-06	622	97	13	GO:0098771
GeneOntologyBiologicalProcess	regulation of cardiac conduction	ACE2 ATP2B2 ATP2B3 ATP2B4	9.97e-06	29	97	4	GO:1903779
GeneOntologyBiologicalProcess	chemical homeostasis	CACNA1C PNPLA2 SLC9A8 CNNM2 FATE1 GCM2 RBP4 SLC39A4 EXT2 ITPR1 GSTP1 ERFE TNFSF11 TMTC4 ATP2B2 ATP2B3 ATP2B4 WDR72	1.85e-05	1249	97	18	GO:0048878
GeneOntologyBiologicalProcess	calcium ion homeostasis	CACNA1C FATE1 GCM2 ITPR1 TNFSF11 TMTC4 ATP2B2 ATP2B3 ATP2B4	9.12e-05	389	97	9	GO:0055074
GeneOntologyBiologicalProcess	cardiac conduction	CACNA1C ACE2 ATP2B2 ATP2B3 ATP2B4	1.10e-04	100	97	5	GO:0061337
GeneOntologyBiologicalProcess	intracellular monoatomic cation homeostasis	CACNA1C SLC9A8 FATE1 GCM2 SLC39A4 ITPR1 ERFE TMTC4 ATP2B2 ATP2B3 ATP2B4	1.40e-04	611	97	11	GO:0030003
GeneOntologyBiologicalProcess	intracellular monoatomic ion homeostasis	CACNA1C SLC9A8 FATE1 GCM2 SLC39A4 ITPR1 ERFE TMTC4 ATP2B2 ATP2B3 ATP2B4	1.63e-04	622	97	11	GO:0006873
GeneOntologyBiologicalProcess	cellular homeostasis	CACNA1C PNPLA2 SLC9A8 FATE1 GCM2 SLC39A4 ITPR1 GSTP1 ERFE TMTC4 NOS2 ATP2B2 ATP2B3 ATP2B4	1.94e-04	981	97	14	GO:0019725
GeneOntologyBiologicalProcess	intracellular chemical homeostasis	CACNA1C PNPLA2 SLC9A8 FATE1 GCM2 SLC39A4 ITPR1 GSTP1 ERFE TMTC4 ATP2B2 ATP2B3 ATP2B4	2.06e-04	866	97	13	GO:0055082
GeneOntologyCellularComponent	excitatory synapse	C1QL2 AFDN ATP2B2 ATP2B3 UNC13A	1.64e-04	107	100	5	GO:0060076
GeneOntologyCellularComponent	presynaptic membrane	CACNA1C AFDN CACNA1H ATP2B2 ATP2B3 ATP2B4 UNC13A	3.73e-04	277	100	7	GO:0042734
GeneOntologyCellularComponent	synaptic cleft	C1QL3 LAMA5 C1QL2	5.22e-04	33	100	3	GO:0043083
GeneOntologyCellularComponent	presynaptic active zone membrane	AFDN CACNA1H ATP2B2 ATP2B4	5.36e-04	78	100	4	GO:0048787
GeneOntologyCellularComponent	presynaptic active zone	AFDN CACNA1H ATP2B2 ATP2B4 UNC13A	5.86e-04	141	100	5	GO:0048786
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3 ATP2B4	5.58e-07	4	98	3	IPR022141
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B3 ATP2B4	5.58e-07	4	98	3	PF12424
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B3 ATP2B4	5.58e-07	4	98	3	IPR006408
Domain	-	C1QL3 C1QL4 ERFE C1QL2 TNFSF11	6.31e-06	50	98	5	2.60.120.40
Domain	Tumour_necrosis_fac-like_dom	C1QL3 C1QL4 ERFE C1QL2 TNFSF11	1.32e-05	58	98	5	IPR008983
Domain	C1q_dom	C1QL3 C1QL4 ERFE C1QL2	2.93e-05	34	98	4	IPR001073
Domain	C1Q	C1QL3 C1QL4 ERFE C1QL2	2.93e-05	34	98	4	PS50871
Domain	-	ATP2B2 ATP2B3 ATP2B4	7.47e-05	16	98	3	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP2B2 ATP2B3 ATP2B4	7.47e-05	16	98	3	IPR023298
Domain	ATPase_P-typ_cation-transptr_C	ATP2B2 ATP2B3 ATP2B4	9.03e-05	17	98	3	IPR006068
Domain	Cation_ATPase_C	ATP2B2 ATP2B3 ATP2B4	9.03e-05	17	98	3	PF00689
Domain	Cation_ATPase_N	ATP2B2 ATP2B3 ATP2B4	1.08e-04	18	98	3	PF00690
Domain	Cation_ATPase_N	ATP2B2 ATP2B3 ATP2B4	1.08e-04	18	98	3	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2B2 ATP2B3 ATP2B4	1.28e-04	19	98	3	IPR004014
Domain	WD40_repeat_dom	DCAF1 CORO2A DPH7 KIF21A SF3B3 WDR97 WDR35 WDR72	1.70e-04	297	98	8	IPR017986
Domain	WD40/YVTN_repeat-like_dom	DCAF1 CORO2A DPH7 KIF21A SF3B3 WDR97 WDR35 WDR72	3.82e-04	335	98	8	IPR015943
Domain	C1Q	C1QL3 C1QL4 C1QL2	6.22e-04	32	98	3	SM00110
Domain	C1q	C1QL3 C1QL4 C1QL2	6.22e-04	32	98	3	PF00386
Domain	WD_REPEATS_1	DCAF1 CORO2A DPH7 KIF21A WDR97 WDR35 WDR72	6.55e-04	278	98	7	PS00678
Domain	WD_REPEATS_2	DCAF1 CORO2A DPH7 KIF21A WDR97 WDR35 WDR72	6.69e-04	279	98	7	PS50082
Domain	WD_REPEATS_REGION	DCAF1 CORO2A DPH7 KIF21A WDR97 WDR35 WDR72	6.69e-04	279	98	7	PS50294
Domain	ATPase_P-typ_cyto_domN	ATP2B2 ATP2B3 ATP2B4	8.12e-04	35	98	3	IPR023299
Domain	P_typ_ATPase	ATP2B2 ATP2B3 ATP2B4	8.82e-04	36	98	3	IPR001757
Domain	ATPase_P-typ_P_site	ATP2B2 ATP2B3 ATP2B4	8.82e-04	36	98	3	IPR018303
Domain	ATPASE_E1_E2	ATP2B2 ATP2B3 ATP2B4	8.82e-04	36	98	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP2B2 ATP2B3 ATP2B4	9.56e-04	37	98	3	IPR008250
Domain	E1-E2_ATPase	ATP2B2 ATP2B3 ATP2B4	9.56e-04	37	98	3	PF00122
Domain	Hydrolase_3	ATP2B2 ATP2B3	1.19e-03	10	98	2	PF08282
Domain	VDCCAlpha1	CACNA1C CACNA1H	1.19e-03	10	98	2	IPR002077
Domain	WD40_repeat_CS	CORO2A DPH7 KIF21A WDR97 WDR72	1.73e-03	164	98	5	IPR019775
Domain	-	DCAF1 CORO2A DPH7 KIF21A WDR97 WDR35 WDR72	1.86e-03	333	98	7	2.130.10.10
Domain	ARM-type_fold	DCAF1 CKAP5 ARFGEF1 ITPR1 HEATR9 SERAC1 FMNL1	2.06e-03	339	98	7	IPR016024
Pathway	WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION	CACNA1C ITPR1 ATP2B2 ATP2B3 ATP2B4 KDM1A	9.93e-09	36	62	6	M39831
Pathway	REACTOME_PLATELET_HOMEOSTASIS	PDE1B ITPR1 NOS2 ATP2B2 ATP2B3 ATP2B4	9.72e-07	76	62	6	MM15051
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	CACNA1C PDE1B ITPR1 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4	1.04e-06	178	62	8	M2890
Pathway	REACTOME_PLATELET_HOMEOSTASIS	PDE1B ITPR1 NOS2 ATP2B2 ATP2B3 ATP2B4	2.02e-06	86	62	6	M916
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	ITPR1 ATP2B2 ATP2B3 ATP2B4	5.52e-06	27	62	4	MM15053
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	ITPR1 ATP2B2 ATP2B3 ATP2B4	6.42e-06	28	62	4	M924
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	ATP2B2 ATP2B3 ATP2B4	1.73e-05	12	62	3	M27326
Pathway	REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE	PDE1B ITPR1 NOS2	2.25e-05	13	62	3	MM15015
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	ATP2B2 ATP2B3 ATP2B4	2.85e-05	14	62	3	MM15052
Pathway	REACTOME_CARDIAC_CONDUCTION	CACNA1C ITPR1 ATP2B2 ATP2B3 ATP2B4	8.78e-05	103	62	5	MM15196
Pathway	REACTOME_ION_HOMEOSTASIS	ITPR1 ATP2B2 ATP2B3 ATP2B4	9.10e-05	54	62	4	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	ITPR1 ATP2B2 ATP2B3 ATP2B4	9.10e-05	54	62	4	MM15202
Pathway	REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE	PDE1B ITPR1 NOS2	1.18e-04	22	62	3	M915
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	CACNA1C NRTN SPTA1 CACNA1H	1.66e-04	63	62	4	M11187
Pathway	REACTOME_MUSCLE_CONTRACTION	CACNA1C ITPR1 CACNA1H ATP2B2 ATP2B3 ATP2B4	2.60e-04	203	62	6	M5485
Pathway	REACTOME_CARDIAC_CONDUCTION	CACNA1C ITPR1 ATP2B2 ATP2B3 ATP2B4	2.62e-04	130	62	5	M27454
Pathway	REACTOME_MUSCLE_CONTRACTION	CACNA1C ITPR1 ATP2B2 ATP2B3 ATP2B4	7.81e-04	165	62	5	MM15026
Pathway	REACTOME_HEMOSTASIS	PDE1B KIF21A ITPR1 PCYOX1L NOS2 ATP2B2 ATP2B3 ATP2B4 KDM1A	8.22e-04	571	62	9	MM14472
Pathway	REACTOME_NCAM1_INTERACTIONS	CACNA1C NRTN CACNA1H	8.23e-04	42	62	3	M7169
Pathway	REACTOME_CGMP_EFFECTS	PDE1B ITPR1	8.37e-04	10	62	2	MM15054
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1C ITPR1 ATP2B2 ATP2B3 ATP2B4	9.13e-08	38	102	5	30786075
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	12209837
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	12784250
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	8245032
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	11152753
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	10434059
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	15101689
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B2 ATP2B3 ATP2B4	9.78e-08	4	102	3	8634322
Pubmed	The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins.	C1QL3 C1QL4 C1QL2	2.44e-07	5	102	3	21262840
Pubmed	Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.	ATP2B2 ATP2B3 ATP2B4	2.44e-07	5	102	3	17938178
Pubmed	Distinct expression of C1q-like family mRNAs in mouse brain and biochemical characterization of their encoded proteins.	C1QL3 C1QL4 C1QL2	4.87e-07	6	102	3	20525073
Pubmed	Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.	ATP2B2 ATP2B3 ATP2B4	4.87e-07	6	102	3	12767889
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2B2 ATP2B3 ATP2B4	1.36e-06	8	102	3	10951186
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	VPS13C CKAP5 ITPR1 WDR35 ATP2B2 KDM1A	2.23e-06	128	102	6	30995482
Pubmed	LRRC15 mediates an accessory interaction with the SARS-CoV-2 spike protein.	ACE2 LRRC15	8.52e-06	2	102	2	36735681
Pubmed	Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.	ATP2B2 ATP2B3	8.52e-06	2	102	2	8187550
Pubmed	LRRC15 inhibits SARS-CoV-2 cellular entry in trans.	ACE2 LRRC15	8.52e-06	2	102	2	36228039
Pubmed	Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.	ACE2 LRRC15	8.52e-06	2	102	2	36757924
Pubmed	Interaction of the C9orf72-Amyotrophic Lateral Sclerosis-Related Proline-Arginine Dipeptide Repeat Protein with the RNA-Binding Protein NOVA1 Causes Decreased Expression of UNC13A Due to Enhanced Inclusion of Cryptic Exons, Which Is Reversed by Betulin Treatment.	UNC13A NOVA1	8.52e-06	2	102	2	37887320
Pubmed	FBXO24 Suppresses Breast Cancer Tumorigenesis by Targeting LSD1 for Ubiquitination.	FBXO24 KDM1A	8.52e-06	2	102	2	37540490
Pubmed	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.	ATP2B2 ATP2B4	8.52e-06	2	102	2	1313367
Pubmed	Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.	ATP2B3 ATP2B4	8.52e-06	2	102	2	1531651
Pubmed	CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.	CACNA1C CACNA1H	8.52e-06	2	102	2	32332705
Pubmed	Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.	ATP2B2 ATP2B4	8.52e-06	2	102	2	22252018
Pubmed	Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.	ATP2B2 ATP2B4	8.52e-06	2	102	2	25690014
Pubmed	Crucial Role of Lysine-Specific Histone Demethylase 1 in RANKL-Mediated Osteoclast Differentiation.	TNFSF11 KDM1A	8.52e-06	2	102	2	36835016
Pubmed	IL-17 Receptor Signaling in Osteoblasts/Osteocytes Mediates PTH-Induced Bone Loss and Enhances Osteocytic RANKL Production.	TNFSF11 IL17RA	8.52e-06	2	102	2	30399207
Pubmed	Diltiazem inhibits SARS-CoV-2 cell attachment and internalization and decreases the viral infection in mouse lung.	CACNA1C ACE2	8.52e-06	2	102	2	35176124
Pubmed	Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2.	CACNA1C CACNA1H	8.52e-06	2	102	2	23686856
Pubmed	Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes.	CACNA1C CACNA1H	8.52e-06	2	102	2	18832749
Pubmed	Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A.	KIF21A ARFGEF1	8.52e-06	2	102	2	19020088
Pubmed	Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.	ATP2B2 ATP2B4	8.52e-06	2	102	2	16216224
Pubmed	140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.	PDE1B KIF21A CKAP5 ITPR1 ATP2B3 ATP2B4	8.97e-06	163	102	6	16512683
Pubmed	Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes.	PNPLA2 PLIN1	2.55e-05	3	102	2	22535977
Pubmed	Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population.	CACNA1C CACNA1H	2.55e-05	3	102	2	26216687
Pubmed	Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl).	PNPLA2 PLIN1	2.55e-05	3	102	2	19850935
Pubmed	Expression of voltage sensitive calcium channel (VSCC) L-type Cav1.2 (alpha1C) and T-type Cav3.2 (alpha1H) subunits during mouse bone development.	CACNA1C CACNA1H	2.55e-05	3	102	2	16059921
Pubmed	Chronic TNFalpha and cAMP pre-treatment of human adipocytes alter HSL, ATGL and perilipin to regulate basal and stimulated lipolysis.	PNPLA2 PLIN1	2.55e-05	3	102	2	19695247
Pubmed	T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.	CACNA1C CACNA1H	2.55e-05	3	102	2	31919478
Pubmed	Distinct mechanisms regulate ATGL-mediated adipocyte lipolysis by lipid droplet coat proteins.	PNPLA2 PLIN1	2.55e-05	3	102	2	23204327
Pubmed	RBP4/Lp-PLA2/Netrin-1 signaling regulation of cognitive dysfunction in diabetic nephropathy complicated with silent cerebral infarction.	PLA2G7 RBP4	2.55e-05	3	102	2	28704853
Pubmed	Association of single nucleotide polymorphisms in CACNA 1A/CACNA 1C/CACNA 1H calcium channel genes with diabetic peripheral neuropathy in Chinese population.	CACNA1C CACNA1H	2.55e-05	3	102	2	29581247
Pubmed	Human frame shift mutations affecting the carboxyl terminus of perilipin increase lipolysis by failing to sequester the adipose triglyceride lipase (ATGL) coactivator AB-hydrolase-containing 5 (ABHD5).	PNPLA2 PLIN1	2.55e-05	3	102	2	21757733
Pubmed	Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.	PNPLA2 PLIN1	2.55e-05	3	102	2	16679289
Pubmed	The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.	ATP2B2 ATP2B4	2.55e-05	3	102	2	17689535
Pubmed	Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells.	ATP2B2 ATP2B4	2.55e-05	3	102	2	20211863
Pubmed	Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.	CACNA1C CACNA1H	2.55e-05	3	102	2	37739992
Pubmed	Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes.	PNPLA2 PLIN1	2.55e-05	3	102	2	17114792
Pubmed	Intracellular infection and immune system cues rewire adipocytes to acquire immune function.	PNPLA2 NOS2	5.09e-05	4	102	2	35508110
Pubmed	Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein.	PNPLA2 PLIN1	5.09e-05	4	102	2	21393244
Pubmed	Cardiotrophin-1 stimulates lipolysis through the regulation of main adipose tissue lipases.	PNPLA2 PLIN1	5.09e-05	4	102	2	25351614
Pubmed	C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis.	C1QL4 C1QL2	5.09e-05	4	102	2	23449976
Pubmed	Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing.	KIF21A ARFGEF1	5.09e-05	4	102	2	22084092
Pubmed	Analysis of lipolytic protein trafficking and interactions in adipocytes.	PNPLA2 PLIN1	5.09e-05	4	102	2	17189257
Pubmed	Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle.	PNPLA2 PLIN1	5.09e-05	4	102	2	26411340
Pubmed	Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm.	ACE2 NOS2	5.09e-05	4	102	2	16574921
Pubmed	Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity.	PNPLA2 PLIN1	5.09e-05	4	102	2	25535287
Pubmed	Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.	CACNA1C CACNA1H	5.09e-05	4	102	2	21788606
Pubmed	ERα regulates lipid metabolism in bone through ATGL and perilipin.	PNPLA2 PLIN1	5.09e-05	4	102	2	23296636
Pubmed	AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance.	PNPLA2 PLIN1	5.09e-05	4	102	2	18390901
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PNPLA2 COG7 ACP2 RNF8 ARFGEF1 PCDHAC2 TMTC4 ADGRE5 ATP2B4 PCDH9 NOVA1 WDR72	6.63e-05	1061	102	12	33845483
Pubmed	Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.	PDE1B CORO2A SPTA1 ITPR1 ATP2B2	7.55e-05	147	102	5	16959763
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CACNA1C MYH4 SPTA1 KIF21A DNAH2 TRIM43 CHD3 TMEM43 TRIM43B SF3B3 SYNE2 PLIN1 ATP2B2 ATP2B3	8.18e-05	1442	102	14	35575683
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP2B2 ATP2B3 ATP2B4	8.47e-05	29	102	3	15071553
Pubmed	Physical and genetic maps of the deafwaddler region on distal mouse Chr 6.	ITPR1 ATP2B2	8.47e-05	5	102	2	9615221
Pubmed	Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication.	ACE2 KDM1A	8.47e-05	5	102	2	34031383
Pubmed	A postprandial FGF19-SHP-LSD1 regulatory axis mediates epigenetic repression of hepatic autophagy.	SPTA1 KDM1A	8.47e-05	5	102	2	28446510
Pubmed	Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins.	C1QL3 C1QL2	8.47e-05	5	102	2	27133466
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	SPTA1 CACNA1H	8.47e-05	5	102	2	29720258
Pubmed	HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation.	MYH4 PNPLA2 PLIN1	1.14e-04	32	102	3	33732701
Pubmed	Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.	ATP2B2 ATP2B4	1.27e-04	6	102	2	12763866
Pubmed	Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid arthritis.	TNFSF11 IL17RA	1.27e-04	6	102	2	17876645
Pubmed	Direct interaction of Gas41 and Myc encoded by amplified genes in nervous system tumours.	RNF8 KDM1A	1.27e-04	6	102	2	22068108
Pubmed	Molecular genetic analysis of distal mouse chromosome 6 defines gene order and positions of the deafwaddler and opisthotonos mutations.	ITPR1 ATP2B2	1.27e-04	6	102	2	8530061
Pubmed	Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.	ATP2B2 ATP2B4	1.27e-04	6	102	2	11274188
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	DCAF1 CNNM2 CKAP5 EXT2 TMEM43 CLPB WDR97 AFDN TTC13 ANKRD52 KDM1A	1.38e-04	974	102	11	28675297
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	MYH4 SLC9A8 DPH7 TMEM43 CLPB WDR35 ARHGAP45 ATP2B2 STK24 ATP2B4	1.71e-04	832	102	10	36724073
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1H	1.77e-04	7	102	2	12900400
Pubmed	Protein phosphatase 6 regulatory subunits composed of ankyrin repeat domains.	ANKRD44 ANKRD52	2.36e-04	8	102	2	18186651
Pubmed	Mutations in a plasma membrane Ca2+-ATPase gene cause deafness in deafwaddler mice.	ITPR1 ATP2B2	2.36e-04	8	102	2	9697703
Pubmed	Intracellular calcium plays an essential role in cardiac development.	CACNA1C CACNA1H	2.36e-04	8	102	2	12761855
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SLC9A8 CORO2A TLL2 SYNE2	2.38e-04	102	102	4	10231032
Pubmed	PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.	CACNA1C DDX60 PCDH9	2.41e-04	41	102	3	21282332
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	DHX37 CLPB SYNE2 ATP2B3 RAVER1	2.96e-04	197	102	5	20811636
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1C CACNA1H	3.03e-04	9	102	2	16382099
Pubmed	Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2.	ANKRD44 ANKRD52	3.03e-04	9	102	2	21187329
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KIF21A CKAP5 CHD3 SF3B3 PRCC STK24 KDM1A RAVER1	3.24e-04	582	102	8	20467437
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CHD3 SF3B3 AFDN ATP2B2 ATP2B3	3.32e-04	202	102	5	24639526
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RUNDC3B ANKRD44 GFOD1 AFDN ANKRD52 STK24 FMNL1	3.53e-04	446	102	7	24255178
Pubmed	Regulation of DLK1 by the maternally expressed miR-379/miR-544 cluster may underlie callipyge polar overdominance inheritance.	MYH4 KDM1A	3.77e-04	10	102	2	26487685
Pubmed	Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.	CACNA1C CACNA1H	3.77e-04	10	102	2	24778262
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	DHX37 VPS13C DNAH2 LAMA5 ITPR1 CLPB SYNE2 PCDH9 KDM1A	3.84e-04	754	102	9	35906200
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNA1C CACNA1H	4.60e-04	11	102	2	18809727
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DCAF1 GALC RFX3 SF3B3 PRCC WDR35 AFDN FERMT2 ATP2B2 PCDH9 KDM1A RAVER1	4.97e-04	1321	102	12	27173435
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDE1B KIF21A CKAP5 ARMCX4 SYNE2 AFDN ATP2B4 UNC13A KDM1A LRRC15	5.41e-04	963	102	10	28671696
Pubmed	Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation.	ANKRD44 ANKRD52	5.51e-04	12	102	2	35512830
Interaction	GPR173 interactions	ACP2 SLC39A4 ATP2B2 ATP2B4 YIPF3	4.83e-06	51	98	5	int:GPR173
Interaction	CYP2B6 interactions	ATP2B2 ATP2B3 ATP2B4	6.13e-06	8	98	3	int:CYP2B6
Interaction	LILRB4 interactions	ADGRE5 ATP2B2 ATP2B3 ATP2B4	9.84e-06	28	98	4	int:LILRB4
Interaction	C5AR1 interactions	ACP2 SLC39A4 ADGRE5 ATP2B2 ATP2B3 ATP2B4 YIPF3	1.03e-05	154	98	7	int:C5AR1
Interaction	S1PR1 interactions	ACP2 CKAP5 SLC39A4 ATP2B2 ATP2B3 YIPF3	1.79e-05	112	98	6	int:S1PR1
Interaction	C17orf78 interactions	ATP2B2 ATP2B3 ATP2B4	2.38e-05	12	98	3	int:C17orf78
Interaction	P2RY8 interactions	ARFGEF1 SLC39A4 ATP2B2 ATP2B3 ATP2B4 YIPF3 LRRC15	2.72e-05	179	98	7	int:P2RY8
Interaction	FZD7 interactions	ACP2 SLC39A4 ADGRE5 ATP2B2 ATP2B4	3.67e-05	77	98	5	int:FZD7
Interaction	PLEC interactions	SPTA1 ACP2 LAMA5 ITPR1 ACE2 GFOD1 SYNE2 NOS2 FMNL1 KDM1A	4.63e-05	430	98	10	int:PLEC
Interaction	HSD17B6 interactions	ATP2B2 ATP2B3 ATP2B4	4.86e-05	15	98	3	int:HSD17B6
Interaction	S1PR4 interactions	ACP2 SLC39A4 ADGRE5 ATP2B2 ATP2B4 YIPF3	5.57e-05	137	98	6	int:S1PR4
Interaction	UPK2 interactions	CNNM2 ARFGEF1 C1QL4 TNFSF11 ADGRE5 PCDH9	6.80e-05	142	98	6	int:UPK2
Interaction	PRG2 interactions	LAMA5 C1QL4 CHD3 EXT2 ERFE TLL2 TTC13 IL17RA	7.59e-05	285	98	8	int:PRG2
Cytoband	11p12-p11	ACP2 EXT2	4.87e-05	5	102	2	11p12-p11
Cytoband	10q23-q24	RBP4 TLL2	1.74e-04	9	102	2	10q23-q24
GeneFamily	Endogenous ligands\|C1q and TNF related	C1QL3 C1QL4 ERFE C1QL2	6.41e-07	18	71	4	1372
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B3 ATP2B4	4.79e-06	9	71	3	1209
GeneFamily	Protein phosphatase 6 regulatory subunits	ANKRD44 ANKRD52	2.26e-04	6	71	2	699
GeneFamily	WD repeat domain containing	CORO2A DPH7 KIF21A WDR97 WDR35 WDR72	5.70e-04	262	71	6	362
Coexpression	MARTENS_BOUND_BY_PML_RARA_FUSION	CACNA1C GALC CORO2A ITPR1 GFOD1 ARHGAP45 STK24 ATP2B4 FMNL1 RAVER1	1.18e-05	456	102	10	M2094
Coexpression	GSE7460_CD8_TCELL_VS_TREG_ACT_UP	ITPR1 BPNT2 ADGRE5 TTC13 CENATAC ATP2B4 DSE	1.36e-05	200	102	7	M5683
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COG7 LAMA5 ACE2 VILL CACNA1H PCDH9	3.04e-06	174	102	6	c58328c2f262506a4518f49f148e29874faf9171
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C ARFGEF1 ITPR1 ANKRD44 SYNE2 CENATAC	4.74e-06	188	102	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1C IQCH RBP4 CLPB IL17RA FERMT2	6.76e-06	200	102	6	401d50fa394fa863fa7836344110ae5c7af3250a
Drug	p-hydroxyhippuric acid	ACE2 ATP2B2 ATP2B3 ATP2B4	3.53e-07	14	101	4	CID000151012
Drug	strontium	MYH4 CNNM2 ITPR1 ATP2B2 ATP2B3 ATP2B4	5.75e-07	68	101	6	CID000104798
Drug	dihydropyridine	CACNA1C ITPR1 ACE2 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4	2.38e-06	193	101	8	CID000104822
Drug	mercury	CACNA1C CLCA4 ACP2 ITPR1 ACE2 TNFSF11 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4 KDM1A	5.11e-06	542	101	12	CID000023931
Drug	1sqc	ATP2B2 ATP2B3 ATP2B4	9.94e-06	10	101	3	CID000444279
Drug	verapamil	CACNA1C MYH4 RBP4 ITPR1 GSTP1 ACE2 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4	1.14e-05	490	101	11	CID000002520
Drug	2,5-dimethylquinone	ATP2B2 ATP2B3 ATP2B4	1.36e-05	11	101	3	CID000008718
Drug	Felodipine	CACNA1C PDE1B CACNA1H	1.36e-05	11	101	3	DB01023
Drug	TMB-8	CACNA1C ITPR1 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4	1.37e-05	176	101	7	CID000005494
Drug	AC1L2AC7	PLA2G7 CACNA1C ITPR1 ACE2 CACNA1H	1.39e-05	69	101	5	CID000068733
Drug	1vyq	ATP2B2 ATP2B3 ATP2B4	1.81e-05	12	101	3	CID004369390
Drug	Ro 46861	ATP2B2 ATP2B3 ATP2B4	1.81e-05	12	101	3	CID000003128
Drug	mag-fura-2	ITPR1 ATP2B2 ATP2B3 ATP2B4	2.15e-05	37	101	4	CID000123839
Drug	8-hydroxycoumarin	ATP2B2 ATP2B3 ATP2B4	2.35e-05	13	101	3	CID000122783
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	DCAF1 NRTN ITPR1 C22orf31 AFDN NOS2 UNC13A	2.73e-05	196	101	7	4406_UP
Drug	Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A	PNPLA2 CNNM2 ATP2B3 STK24 ATP2B4 UNC13A LRRC23	2.92e-05	198	101	7	3575_UP
Drug	lanthanum	CACNA1C ITPR1 CACNA1H ATP2B2 ATP2B3 ATP2B4	3.24e-05	136	101	6	CID000023926
Drug	clotrimazole	CLCA4 GSTP1 NOS2 ATP2B2 ATP2B3 ATP2B4	4.29e-05	143	101	6	CID000002812
Drug	nimodipine	CACNA1C ITPR1 CACNA1H ATP2B2 ATP2B3 ATP2B4	4.64e-05	145	101	6	CID000004497
Drug	AC1L88YH	ATP2B2 ATP2B3 ATP2B4	5.51e-05	17	101	3	CID000374551
Drug	Bay K 8644	CACNA1C ITPR1 CACNA1H ATP2B2 ATP2B3 ATP2B4	5.60e-05	150	101	6	CID000002303
Drug	AC1L1G0K	NOS2 ATP2B2 ATP2B3 ATP2B4	6.63e-05	49	101	4	CID000003473
Drug	nitrous oxide	TNFSF11 NOS2 ATP2B2 ATP2B3 ATP2B4	6.90e-05	96	101	5	CID000000948
Drug	KW-3049	CACNA1C ACE2 CACNA1H NOS2	7.18e-05	50	101	4	CID000002324
Drug	halothane	CACNA1C ITPR1 GSTP1 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4	7.96e-05	314	101	8	CID000003562
Drug	indo-1	CACNA1C ITPR1 ATP2B2 ATP2B3 ATP2B4	7.99e-05	99	101	5	CID000105060
Drug	calmidazolium chloride	PDE1B ITPR1 NOS2 ATP2B2 ATP2B3 ATP2B4	8.01e-05	160	101	6	CID000002531
Drug	2-(aminomethyl)pyrrolidine	SPTA1 ITPR1 NOS2 ATP2B2 ATP2B3 ATP2B4	8.29e-05	161	101	6	CID000072032
Drug	nifedipine	CACNA1C MYH4 ITPR1 ACE2 CACNA1H NOS2 ATP2B2 ATP2B3 ATP2B4	9.69e-05	415	101	9	CID000004485
Drug	trifluoperazine	MYH4 PDE1B SPTA1 AFDN NOS2 ATP2B2 ATP2B3 ATP2B4	9.90e-05	324	101	8	CID000005566
Drug	2brh	ATP2B2 ATP2B3 ATP2B4	1.06e-04	21	101	3	CID000848641
Drug	felodipine	CACNA1C PDE1B ITPR1 GSTP1 ACE2 CACNA1H	1.08e-04	169	101	6	CID000003333
Drug	bepafant	PLA2G7 NOS2	1.16e-04	4	101	2	ctd:C063964
Drug	W7 hydrochloride	CACNA1C PDE1B ITPR1 NOS2 ATP2B2 ATP2B3 ATP2B4	1.27e-04	250	101	7	CID000005681
Drug	toxaphene	ATP2B2 ATP2B3 ATP2B4 LRRC23	1.29e-04	58	101	4	CID005284469
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B3 ATP2B4	6.84e-07	6	97	3	DOID:0050429 (implicated_via_orthology)
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	TMEM43 SYNE2	6.39e-05	4	97	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	TMEM43 SYNE2	1.06e-04	5	97	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	TMEM43 SYNE2	1.06e-04	5	97	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	TMEM43 SYNE2	1.59e-04	6	97	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	TMEM43 SYNE2	1.59e-04	6	97	2	C0410189
Disease	Epilepsy, Generalized	CLPB CACNA1H	1.59e-04	6	97	2	C0014548
Disease	myocardial infarction (is_marker_for)	PLA2G7 RBP4 TNFSF11	1.75e-04	33	97	3	DOID:5844 (is_marker_for)
Disease	Kidney Diseases	CNNM2 RBP4 GSTP1 NOS2	2.07e-04	88	97	4	C0022658
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	TMEM43 SYNE2	2.22e-04	7	97	2	C0751337
Disease	nitric oxide exhalation measurement	CACNA1C NOS2 LRRC23	2.67e-04	38	97	3	EFO_0005536
Disease	3-Methylglutaconic aciduria	CLPB SERAC1	2.96e-04	8	97	2	cv:C3696376
Disease	Sudden Cardiac Death	CACNA1C TMEM43	2.96e-04	8	97	2	C0085298
Disease	Hypertensive disease	CACNA1C GSTP1 ACE2 NOS2 ATP2B3	4.19e-04	190	97	5	C0020538
Disease	carbohydrate measurement	ATP2B2 ATP2B4 KDM1A	4.72e-04	46	97	3	EFO_0004998
Disease	Hypoglycemia	CACNA1C SERAC1	5.77e-04	11	97	2	C0020615
Disease	rotator cuff tear, shoulder impingement syndrome	C5orf63 STK24	6.91e-04	12	97	2	EFO_1001178, EFO_1001250
Disease	Necrosis	RBP4 GSTP1 NOS2	7.98e-04	55	97	3	C0027540
Disease	Sarcomatoid Renal Cell Carcinoma	GSTP1 PRCC SYNE2 YIPF3	8.57e-04	128	97	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	GSTP1 PRCC SYNE2 YIPF3	8.57e-04	128	97	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	GSTP1 PRCC SYNE2 YIPF3	8.57e-04	128	97	4	C1266044
Disease	Papillary Renal Cell Carcinoma	GSTP1 PRCC SYNE2 YIPF3	8.57e-04	128	97	4	C1306837
Disease	Renal Cell Carcinoma	GSTP1 PRCC SYNE2 YIPF3	8.57e-04	128	97	4	C0007134
Disease	coronary artery disease (is_marker_for)	PLA2G7 RBP4 NOS2	1.42e-03	67	97	3	DOID:3393 (is_marker_for)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	GSTP1 PRCC SYNE2 YIPF3	1.47e-03	148	97	4	C0279702
Disease	sphingosine 1-phosphate measurement	ITPR1 C1QL2	1.58e-03	18	97	2	EFO_0800185
Disease	Autistic Disorder	CACNA1C RNF8 GSTP1 CACNA1H NOS2	1.73e-03	261	97	5	C0004352
Disease	cerebral infarction (is_marker_for)	PLA2G7 RBP4	1.76e-03	19	97	2	DOID:3526 (is_marker_for)
Disease	response to alcohol	C1QL3 AFDN NOVA1	1.96e-03	75	97	3	EFO_0005526
Disease	Asthma	PLA2G7 GSTP1 NOS2	2.36e-03	80	97	3	C0004096
Disease	type 2 diabetes mellitus (is_implicated_in)	PLA2G7 RBP4 GSTP1 NOS2	2.48e-03	171	97	4	DOID:9352 (is_implicated_in)
Disease	congestive heart failure (is_marker_for)	PLA2G7 RBP4 ACE2	2.53e-03	82	97	3	DOID:6000 (is_marker_for)
Disease	response to peginterferon alfa-2a	IQCH CORO2A	3.05e-03	25	97	2	EFO_0010103
Disease	Cardiac Arrhythmia	CACNA1C CNNM2	3.05e-03	25	97	2	C0003811
Disease	depressive symptom measurement, response to antidepressant	ANKRD44 STK24 ATP2B4	3.09e-03	88	97	3	EFO_0007006, GO_0036276

Protein segments in the cluster

Peptide	Gene	Start	Entry
QDSMSRAKANWLRAF	UNC13A	441	Q9UPW8
MLWFQGNSMQLARSS	C5orf63	1	A6NC05
QKNIAGALAFWMANA	AFDN	681	P55196
NMADNWLGSIARATM	COG7	676	P83436
AKQLVWRGANVNMKT	ASB4	156	Q9Y574
AQMVNSQAANIRSGW	ARFGEF1	1261	Q9Y6D6
SMWADLCKNNQVRAS	C1QL3	186	Q5VWW1
WADLMKNGQVRASAI	C1QL4	171	Q86Z23
QSSARMKLNWAVAAG	ADGRE5	376	P48960
ALTNIWMARTCAKQN	C22orf31	36	O95567
LMSGANVNAKDTLWL	ANKRD52	61	Q8NB46
NWNAVSKAGAGMDTR	ARMCX4	811	Q5H9R4
DNFSSIVKAVMWGRN	ATP2B2	856	Q01814
NFTSIVKAVMWGRNV	ATP2B3	831	Q16720
DNFTSIVKAVMWGRN	ATP2B4	821	P23634
QKAAMWASTPRASAA	RAVER1	586	Q8IY67
QDGNSEAAMKIQATW	IQCH	366	Q86VS3
MQRWKAAALASVLCS	NRTN	1	Q99748
RIKNWGSGMTFQDTL	NOS2	86	P35228
GWMRNNLSLGDALAK	PNPLA2	421	Q96AD5
TLAKMWNVVQSNNGI	DCAF1	721	Q9Y4B6
RQLQKNSGWDTMGSE	IL17RA	846	Q96F46
NAWSPVMRARKSSFN	ARHGAP45	566	Q92619
KTAMNWRLSARNAAR	ITPR1	1581	Q14643
QMIALWAQSSGNADA	CELF2-AS1	31	Q8N7Q2
TSWIKNGNVEQARMV	DDX60	1081	Q8IY21
LWLKADGNRLRSAQM	LRRC23	116	Q53EV4
WAASSVEVMAVAAKN	PCYOX1L	451	Q8NBM8
IRKWNGLLSAMADAD	PLSCR4	276	Q9NRQ2
IRQAMFQLLQSKGSW	OR51T1	301	Q8NGJ9
AAQRSKQGAEWMSPN	PCDH9	846	Q9HC56
WKERAASGITNQMSI	PDE1B	496	Q01064
AWMLFVRQSDKGVNG	ERFE	81	Q4G0M1
KFVMRNGSGNWLADQ	DSE	331	Q9UL01
ILSGARVNAKDNMWL	ANKRD44	61	Q8N8A2
QLRGINASSMAWARL	LAMA5	2191	O15230
AWAMVDGGSNVKARS	BPNT2	216	Q9NX62
SAWVNKIQVLMAAAS	PLA2G7	36	Q13093
AQWGASVAMQAVSRR	PLIN1	261	O60240
KVIAMDSDSGQNAWL	PCDHAC2	606	Q9Y5I4
MAGKRSGWSRAALLQ	ACP2	1	P11117
ALATVNAWAEQTGMK	CKAP5	961	Q14008
WKTSAVQRMGFGNLN	KDM1A	646	O60341
SWQAAIDAARQAKLM	CACNA1C	51	Q13936
GTSMWADLCKNGQVR	C1QL2	216	Q7Z5L3
EGMRKNGTWLQATAA	DPH7	401	Q9BTV6
MTILGAKWREFSANN	CHD3	186	Q12873
LWKESLANMSAIGVN	C3orf20	206	Q8ND61
KLMSTGTSRWNNRQV	CORO2A	236	Q92828
AALRMLLADQGQSWK	GSTP1	16	P09211
WTLALENVVGAKNMN	ACE2	566	Q9BYF1
ALVSTLGQMQWKRAC	FBXO24	161	O75426
IFRLARKWQATSGQM	LYRM1	16	O43325
VSRKVAADWMSNLGF	FMNL1	96	O95466
AADWMSNLGFKRRVQ	FMNL1	101	O95466
RSWKGMNSQVASSLQ	CENATAC	186	Q86UT8
LGWTALMVAAINRNN	CLPB	166	Q9H078
QKAAGSASAKRVWNM	FATE1	56	Q969F0
AKINQGWLDSSRSLM	FERMT2	246	Q96AC1
LFRVSTGDNWNGIMK	CACNA1H	1801	O95180
LSASWQRRAKAMTAA	GALC	6	P54803
VAQMKRTWAGQGASL	DHX37	836	Q8IY37
WQNKFATLLREMAAG	DNAH2	1031	Q9P225
IMNQRTRAKLAAASW	OR10A5	136	Q9H207
AVMEQSGAWVQLSQK	NOVA1	196	P51513
NMENVSSSRAKGRAW	RUNDC3B	131	Q96NL0
GLMGAAFKTWRQQDS	SERAC1	401	Q96JX3
LGVCNNSWIRKNSTM	TRIM43	351	Q96BQ3
LRSNSMKTWGLRAAG	TMEM43	301	Q9BTV4
DDQLSGAQQWMTKSL	PRCC	416	Q92733
IMDNKSLNGVWLNRA	RNF8	76	O76064
VNVTDFKSSWRNGMA	SYNE2	201	Q8WXH0
KRSSQTGEWQNIAIM	GFOD1	351	Q9NXC2
DRSVWGMTQAQSGLA	LRRC15	526	Q8TF66
NFAKSLEGWLSNAMN	RFX3	461	P48380
MDSRAQLWGLALNKR	STK24	1	Q9Y6E0
KAQRHLSGWAMRNTN	GCM2	56	O75603
SWLLQRMQARAAGQT	SLC39A4	141	Q6P5W5
MNGSQAGAAAQAAWL	SMIM41	1	A0A2R8YCJ5
KNMSDVSGWQTFLQA	SLC9A8	246	Q9Y2E8
LQRGMSKANSEVAQW	MYH4	1361	Q9Y623
AAARQMWTSNLSKVR	CCDC54	11	Q8NEL0
ESKGLTLNSNAWMND	CLCA4	491	Q14CN2
GQAAAALPTWKMAAR	CNNM2	16	Q9H8M5
AAWMNLGIVQNSLKR	TMTC4	551	Q5T4D3
AVQRTWTNSKVRMNG	TTC13	541	Q8NBP0
GNAVRMWDLKRFQST	KIF21A	1471	Q7Z4S6
SCQASLWMGRVKQLT	RNF141	136	Q8WVD5
MNSSLALWQFRSGGR	WDR97	216	A6NE52
MSATAKGRVRLLNNW	RBP4	71	P02753
AQAMAQLSRWDRGTN	EXT2	171	Q93063
TGLRMALNSWAAVSK	HEATR9	236	A2RTY3
MRTSLQAVALWGQKA	WDR72	1	Q3MJ13
SNRLWMKFVSDGSIN	TLL2	551	Q9Y6L7
SGNIKNWTSLMAAVA	VPS13C	2306	Q709C8
ELSGWMNEKTAAINA	SPTA1	381	P02549
KAGNGQWASVIRVMN	SF3B3	856	Q15393
WQGRMSSLQERKAAF	VILL	296	O15195
RGWAKISNMTFSNGK	TNFSF11	191	O14788
NRSIQGMNILFSSWA	TMEM225	6	Q6GV28
QMWQAGKRQASRAFS	YIPF3	96	Q9GZM5
LGVCNNSWIRKNSTM	TRIM43B	351	A6NCK2
WANVSNMTFSNGKLR	UNQ5830/PRO19650/PRO19816	36	Q6UY13
SVVRSMSWNADGQKI	WDR35	116	Q9P2L0