Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessrespiratory system development

LIF GPC3 GLI2 ASS1 WT1 TNRC6C EPAS1

9.57e-06305517GO:0060541
GeneOntologyBiologicalProcessanterior/posterior axis specification

GPC3 WT1 GDF3 TCF7L1

2.40e-0568514GO:0009948
GeneOntologyBiologicalProcessembryonic organ development

LIF NES TCF7L2 GLI2 TNRC6C PPP1R13L GDF3 EPAS1

6.47e-05561518GO:0048568
GeneOntologyBiologicalProcessmyoblast fate commitment

TCF7L2 EPAS1

1.25e-047512GO:0048625
GeneOntologyBiologicalProcessaxis specification

GPC3 WT1 GDF3 TCF7L1

1.75e-04113514GO:0009798
GeneOntologyBiologicalProcesscell fate commitment

TCF7L2 GLI2 WT1 GDF3 TNXB EPAS1

1.79e-04338516GO:0045165
GeneOntologyBiologicalProcesshindgut morphogenesis

TCF7L2 GLI2

2.13e-049512GO:0007442
GeneOntologyBiologicalProcessmuscle structure development

LIF TCF7L2 ASS1 MYOM3 WT1 CMTM5 GDF3 FER1L5 EPAS1

2.26e-04858519GO:0061061
GeneOntologyBiologicalProcesshindgut development

TCF7L2 GLI2

2.66e-0410512GO:0061525
GeneOntologyBiologicalProcessembryonic axis specification

WT1 GDF3 TCF7L1

2.89e-0452513GO:0000578
GeneOntologyBiologicalProcesskidney development

LIF GPC3 GLI2 ASS1 WT1 TNS2

3.00e-04372516GO:0001822
GeneOntologyBiologicalProcesscell proliferation involved in metanephros development

GPC3 WT1

3.25e-0411512GO:0072203
GeneOntologyBiologicalProcessanterior/posterior pattern specification

GPC3 GLI2 WT1 GDF3 TCF7L1

3.54e-04247515GO:0009952
GeneOntologyBiologicalProcessmyoblast differentiation

TCF7L2 CMTM5 GDF3 EPAS1

3.55e-04136514GO:0045445
GeneOntologyBiologicalProcessrenal system development

LIF GPC3 GLI2 ASS1 WT1 TNS2

3.65e-04386516GO:0072001
GeneOntologyBiologicalProcessdiaphragm development

ASS1 WT1

3.89e-0412512GO:0060539
GeneOntologyBiologicalProcesslung development

LIF GPC3 GLI2 TNRC6C EPAS1

5.23e-04269515GO:0030324
GeneOntologyBiologicalProcessrespiratory tube development

LIF GPC3 GLI2 TNRC6C EPAS1

5.59e-04273515GO:0030323
DomainCTNNB1-bd_N

TCF7L2 TCF7L1

4.55e-054522IPR013558
DomainCTNNB1_binding

TCF7L2 TCF7L1

4.55e-054522PF08347
DomainTCF/LEF

TCF7L2 TCF7L1

4.55e-054522IPR024940
DomainVWA_2

INTS6L INTS6

7.56e-055522PF13519
DomainINT_SG_DDX_CT_C

INTS6L INTS6

2.11e-048522PF15300
DomainINT_SG_DDX_CT_C

INTS6L INTS6

2.11e-048522IPR029307
DomainLIM

MICAL1 ABLIM1 LPP

9.37e-0469523PF00412
Domain-

MICAL1 ABLIM1 LPP

9.77e-04705232.10.110.10
DomainZnf_LIM

MICAL1 ABLIM1 LPP

1.02e-0371523IPR001781
DomainLIM_DOMAIN_1

MICAL1 ABLIM1 LPP

1.02e-0371523PS00478
DomainLIM_DOMAIN_2

MICAL1 ABLIM1 LPP

1.02e-0371523PS50023
DomainLIM

MICAL1 ABLIM1 LPP

1.02e-0371523SM00132
DomainVWFA

INTS6L INTS6 HMCN2

1.54e-0382523PS50234
DomainVWA

INTS6L INTS6 HMCN2

1.65e-0384523SM00327
DomainIg_I-set

HMCN2 PXDNL MYOM3 IGDCC4

1.92e-03190524IPR013098
DomainI-set

HMCN2 PXDNL MYOM3 IGDCC4

1.92e-03190524PF07679
DomainVWF_A

INTS6L INTS6 HMCN2

2.64e-0399523IPR002035
DomainCatenin_binding_dom

TCF7L2 TCF7L1

2.94e-0329522IPR027397
Domain-

TCF7L2 TCF7L1

2.94e-03295224.10.900.10
DomainIGc2

HMCN2 PXDNL MYOM3 IGDCC4

4.12e-03235524SM00408
DomainEGF_3

MUC3B HMCN2 ADAM33 TNXB

4.12e-03235524PS50026
DomainIg_sub2

HMCN2 PXDNL MYOM3 IGDCC4

4.12e-03235524IPR003598
DomainEGF-like_dom

MUC3B HMCN2 ADAM33 TNXB

5.06e-03249524IPR000742
DomainEGF_1

MUC3B HMCN2 ADAM33 TNXB

5.50e-03255524PS00022
DomainEGF-like_CS

MUC3B HMCN2 ADAM33 TNXB

5.96e-03261524IPR013032
DomainIG

HMCN2 PXDNL MYOM3 FCAMR IGDCC4

6.19e-03421525SM00409
DomainIg_sub

HMCN2 PXDNL MYOM3 FCAMR IGDCC4

6.19e-03421525IPR003599
DomainEGF_2

MUC3B HMCN2 ADAM33 TNXB

6.29e-03265524PS01186
DomainHMG_box

TCF7L2 TCF7L1

9.57e-0353522PF00505
DomainHMG_BOX_2

TCF7L2 TCF7L1

9.92e-0354522PS50118
DomainHMG

TCF7L2 TCF7L1

9.92e-0354522SM00398
Domain-

TCF7L2 TCF7L1

1.03e-02555221.10.30.10
Domainfn3

MYOM3 TNXB IGDCC4

1.04e-02162523PF00041
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

TCF7L2 TCF7L1 EPAS1

9.31e-0617353M39443
PathwayREACTOME_CA2_PATHWAY

TCF7L2 PDE6A TNRC6C TCF7L1

1.60e-0562354M27321
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7L2 TCF7L1

8.93e-056352MM15542
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7L2 TCF7L1

8.93e-056352M47736
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY

TCF7L2 TCF7L1

1.25e-047352M47465
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7L2 TCF7L1

1.66e-048352MM17229
PathwayREACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS

TCF7L2 TCF7L1

1.66e-048352M27359
PathwayKEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY

TCF7L2 TCF7L1

1.66e-048352M47413
PathwayREACTOME_RUNX3_REGULATES_WNT_SIGNALING

TCF7L2 TCF7L1

1.66e-048352M27821
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY

TCF7L2 TCF7L1

2.66e-0410352M47486
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7L2 TCF7L1

2.66e-0410352MM15156
PathwayKEGG_BASAL_CELL_CARCINOMA

TCF7L2 GLI2 TCF7L1

3.37e-0455353M17807
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY

TCF7L2 TCF7L1

3.89e-0412352M47410
PathwayWP_ENDODERM_DIFFERENTIATION

GLI2 TNRC6C GDF3 TCF7L1

4.16e-04143354M39591
PathwayWP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM

GPC3 GLI2 WT1

4.35e-0460353M40048
PathwayREACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING

TCF7L2 PDE6A TNRC6C TCF7L1

4.50e-04146354M27288
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TCF7L2 TCF7L1

5.35e-0414352M27402
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TCF7L2 TCF7L1

7.03e-0416352MM17241
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION

TCF7L2 TCF7L1

7.96e-0417352M48240
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TCF7L2 CACNA1G TCF7L1

1.01e-0380353M223
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

TCF7L2 TNRC6C TCF7L1

1.66e-0395353M48268
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TCF7L2 TCF7L1

1.87e-0326352MM14793
PathwayKEGG_THYROID_CANCER

TCF7L2 TCF7L1

2.33e-0329352M523
PathwayWP_OLIGODENDROCYTE_SPECIFICATION_AND_DIFFERENTIATION_LEADING_TO_MYELIN_COMPONENTS_FOR_CNS

LIF GLI2

2.49e-0330352M39775
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

ADAM33 TNRC6C

2.83e-0332352M48012
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TCF7L2 TCF7L1

2.83e-0332352MM14975
Pubmed

Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.

TCF7L2 TCF7L1

2.28e-0625329916915
Pubmed

Deletion of an intronic HIF-2α binding site suppresses hypoxia-induced WT1 expression.

WT1 EPAS1

2.28e-06253230468780
Pubmed

A gene family of HMG-box transcription factors with homology to TCF-1.

TCF7L2 TCF7L1

2.28e-0625321741298
Pubmed

Intermediate filament protein nestin is expressed in developing kidney and heart and might be regulated by the Wilms' tumor suppressor Wt1.

NES WT1

2.28e-06253216614054
Pubmed

High-grade astrocytomas show increased Nestin and Wilms's tumor gene (WT1) protein expression.

NES WT1

2.28e-06253219578047
Pubmed

hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.

TCF7L2 WT1 TCF7L1

3.18e-061953335739118
Pubmed

Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling.

TCF7L2 WT1 EPAS1

5.04e-062253325587709
Pubmed

Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.

TCF7L2 GLI2 TCF7L1

5.04e-062253321775418
Pubmed

Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling.

TCF7L2 TCF7L1

6.83e-06353217607356
Pubmed

A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells.

TCF7L2 TCF7L1

6.83e-06353225659031
Pubmed

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators.

TCF7L2 TCF7L1

6.83e-06353224463605
Pubmed

TCF-3, 4 protein expression correlates with beta-catenin expression in MSS and MSI-H colorectal cancer from HNPCC patients but not in sporadic colorectal cancers.

TCF7L2 TCF7L1

6.83e-06353220532534
Pubmed

TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state.

TCF7L2 TCF7L1

6.83e-06353234525377
Pubmed

Diverse LEF/TCF Expression in Human Colorectal Cancer Correlates with Altered Wnt-Regulated Transcriptome in a Meta-Analysis of Patient Biopsies.

TCF7L2 TCF7L1

6.83e-06353232403323
Pubmed

Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.

NES ABLIM1 GLI2 TCF7L1

1.16e-059153421194568
Pubmed

A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells.

TCF7L2 TCF7L1

1.36e-05453233587034
Pubmed

Nestin identifies a subpopulation of rat ventricular fibroblasts and participates in cell migration.

NES WT1

1.36e-05453237458435
Pubmed

Mapping canonical Wnt signaling in the developing and adult retina.

TCF7L2 TCF7L1

1.36e-05453217065530
Pubmed

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.

TCF7L2 GLI2 TCF7L1

1.77e-053353327414999
Pubmed

Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2.

TCF7L2 TCF7L1

2.27e-05553221285352
Pubmed

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

CUL9 PPP1R13L

2.27e-05553215558054
Pubmed

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse.

TCF7L2 TCF7L1

3.40e-0565329488439
Pubmed

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain.

TCF7L2 TCF7L1

3.40e-05653223152144
Pubmed

WT1 Disorder

GPC3 WT1

3.40e-05653232352694
Pubmed

Immunohistochemical markers of neural progenitor cells in the early embryonic human cerebral cortex.

NES WT1

3.40e-05653226972711
Pubmed

Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures.

TCF7L2 TCF7L1

3.40e-05653211731231
Pubmed

Dazap2 modulates transcription driven by the Wnt effector TCF-4.

TCF7L2 TCF7L1

3.40e-05653219304756
Pubmed

PAX6-Related Aniridia

GPC3 WT1

4.76e-05753220301534
Pubmed

β-catenin and γ-catenin are dispensable for T lymphocytes and AML leukemic stem cells.

TCF7L2 TCF7L1

4.76e-05753232820720
Pubmed

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland.

GLI2 TCF7L1

4.76e-05753216678815
Pubmed

RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.

TCF7L2 TCF7L1

4.76e-05753218772112
Pubmed

Wt1 and β-catenin cooperatively regulate diaphragm development in the mouse.

TCF7L2 WT1

4.76e-05753226278035
Pubmed

Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo.

TCF7L2 TCF7L1

4.76e-05753219303461
Pubmed

Connective tissue fibroblasts and Tcf4 regulate myogenesis.

TCF7L2 TCF7L1

6.34e-05853221177349
Pubmed

TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.

TCF7L2 TCF7L1

6.34e-05853232179550
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

INTS6 HMCN2 MID1IP1 SF3B2 EPAS1

7.18e-0528353518854154
Pubmed

Targeted Disruption of the MORG1 Gene in Mice Causes Embryonic Resorption in Early Phase of Development.

WT1 EPAS1

8.15e-05953237509073
Pubmed

Regulation of neural stem cell proliferation and survival by protein arginine methyltransferase 1.

LIF NES

8.15e-05953236440275
Pubmed

Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis.

TCF7L2 TCF7L1

8.15e-05953217335794
Pubmed

The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.

NES GLI2

8.15e-05953211748155
Pubmed

Neighbor of Punc E 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development.

GPC3 IGDCC4

8.15e-05953222497843
Pubmed

Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube.

TCF7L2 GLI2

8.15e-05953216950124
Pubmed

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.

GLI2 WT1 CACNA1G TCF7L1

8.69e-0515253411044609
Pubmed

Expression of signaling components in embryonic eyelid epithelium.

TCF7L2 GLI2

1.02e-041053224498290
Pubmed

Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.

GLI2 WT1

1.02e-041053219842175
Pubmed

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome.

ASS1 WT1

1.02e-041053230046000
Pubmed

A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.

TCF7L2 TCF7L1

1.02e-041053222393260
Pubmed

Resolving the heterogeneity of diaphragmatic mesenchyme: a novel mouse model of congenital diaphragmatic hernia.

TCF7L2 WT1

1.02e-041053233735101
Pubmed

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.

TCF7L2 TCF7L1

1.24e-041153211731265
Pubmed

Tcf7L2 is essential for neurogenesis in the developing mouse neocortex.

TCF7L2 TCF7L1

1.24e-041153229751817
Pubmed

The malformed kidney: disruption of glomerular and tubular development.

GPC3 WT1

1.24e-041153210668924
Pubmed

Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.

CACNA1G PPP1R13L

1.24e-041153227766308
Pubmed

Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation.

GLI2 WT1

1.49e-041253219325248
Pubmed

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.

TCF7L2 TCF7L1

1.49e-041253232414917
Pubmed

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.

TCF7L2 TCF7L1

1.49e-041253210631168
Pubmed

YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis.

WT1 TNXB

1.49e-041253210101119
Pubmed

Rescuing lung development through embryonic inhibition of histone acetylation.

TCF7L2 WT1

1.49e-041253238295182
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TCF7L2 TCF7L1

1.49e-041253211266540
Pubmed

Multifaceted Functions of Rab23 on Primary Cilium-Mediated and Hedgehog Signaling-Mediated Cerebellar Granule Cell Proliferation.

NES GLI2

1.76e-041353234210780
Pubmed

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia.

TCF7L2 TCF7L1

1.76e-041353219718027
Pubmed

Investigation of genes important in neurodevelopment disorders in adult human brain.

TCF7L2 TCF7L1

1.76e-041353226194112
Pubmed

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

TNRC6C SEC31B GDF3

1.77e-047153323400010
Pubmed

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization.

TCF7L2 TCF7L1

2.05e-041453215226261
Pubmed

Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.

TCF7L2 TCF7L1

2.05e-041453233195246
Pubmed

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice.

TCF7L2 TCF7L1

2.05e-041453210090727
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ABLIM1 TCF7L2 LPP WT1 TCF7L1 SF3B2 EPAS1

2.17e-0480853720412781
Pubmed

Phases of canonical Wnt signaling during the development of mouse intestinal epithelium.

TCF7L2 TCF7L1

2.36e-041553217681174
Pubmed

Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor.

GLI2 WT1

2.36e-041553225609427
Pubmed

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation.

TCF7L2 TCF7L1

2.36e-041553215866165
Pubmed

LncRNAs in the Dlk1-Dio3 Domain Are Essential for Mid-Embryonic Heart Development.

GLI2 WT1

2.36e-041553239125754
Pubmed

Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.

ABLIM1 GLI2

2.70e-041653215647317
Pubmed

Mutant Lef1 controls Gata6 in sebaceous gland development and cancer.

TCF7L2 TCF7L1

2.70e-041653230886049
Pubmed

A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours.

NES TCF7L2

2.70e-041653235853870
Pubmed

Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice.

WT1 CACNA1G

2.70e-041653221266775
Pubmed

Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord.

NES GLI2

2.70e-041653228434801
Pubmed

RNAi screen reveals potentially novel roles of cytokines in myoblast differentiation.

CMTM5 GDF3

3.05e-041753223844157
Pubmed

A perivascular niche for multipotent progenitors in the fetal testis.

NES WT1

3.05e-041753230375389
Pubmed

Stage-specific regulation of oligodendrocyte development by Wnt/β-catenin signaling.

TCF7L2 GLI2

3.05e-041753224948802
Pubmed

Suppressor of fused controls mid-hindbrain patterning and cerebellar morphogenesis via GLI3 repressor.

NES GLI2

3.05e-041753221289193
Pubmed

Brain-specific Wt1 deletion leads to depressive-like behaviors in mice via the recruitment of Tet2 to modulate Epo expression.

NES WT1

3.05e-041753232393787
Pubmed

Restriction of Wnt signaling in the dorsal otocyst determines semicircular canal formation in the mouse embryo.

TCF7L2 TCF7L1

3.43e-041853222166339
Pubmed

Wilms Tumor Predisposition

GPC3 WT1

3.43e-041853220301471
Pubmed

Loss of endogenous thymosin β4 accelerates glomerular disease.

NES WT1

3.43e-041853227575556
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

ABLIM1 LPP TNRC6C PPP1R13L

3.46e-0421853433378226
Pubmed

HIF2α in the uterine stroma permits embryo invasion and luminal epithelium detachment.

LIF EPAS1

3.83e-041953229911998
Pubmed

Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4.

TCF7L2 TCF7L1

3.83e-041953220883686
Pubmed

alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.

NES GLI2

3.83e-041953216543460
Pubmed

APC sets the Wnt tone necessary for cerebral cortical progenitor development.

NES GLI2

3.83e-041953228916710
Pubmed

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.

LIF NES WT1

4.19e-049553320843830
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

ABLIM1 CACNA1G

4.25e-042053233397958
Pubmed

Fuz regulates craniofacial development through tissue specific responses to signaling factors.

TCF7L2 GLI2

4.25e-042053221935430
Pubmed

Sequential roles of Hedgehog and Wnt signaling in osteoblast development.

TCF7L2 TCF7L1

4.25e-042053215576404
Pubmed

Function of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interaction.

TCF7L2 TCF7L1

4.25e-042053222573616
Pubmed

Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.

TCF7L2 GLI2

4.25e-042053220637749
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

LIF NES GLI2 GDF3 TCF7L1

4.67e-0442453521731673
Pubmed

Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling.

GLI2 WT1

4.70e-042153229487191
Pubmed

Tcf7l1 protects the anterior neural fold from adopting the neural crest fate.

TCF7L2 TCF7L1

4.70e-042153227302397
Pubmed

Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.

GLI2 WT1

4.70e-042153232855417
Pubmed

Kif7 is required for the patterning and differentiation of the diaphragm in a model of syndromic congenital diaphragmatic hernia.

GLI2 WT1

4.70e-042153223650387
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PLEKHG4B TCF7L2 MAGEL2 GLI2 WT1

4.97e-0443053535044719
GeneFamilyLIM domain containing

MICAL1 ABLIM1 LPP

2.77e-04593931218
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HMCN2 PXDNL MYOM3 IGDCC4

3.91e-04161394593
GeneFamilyIntegrator complex

INTS6L INTS6

4.68e-04153921366
GeneFamilyFibronectin type III domain containing

MYOM3 TNXB IGDCC4

4.92e-03160393555
GeneFamilyImmunoglobulin like domain containing

HMCN2 MYOM3 IGDCC4

8.25e-03193393594
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 ISX ADAM33 TNXB

1.94e-061765258e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 ISX ADAM33 TNXB

1.94e-06176525ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

NES MAGEL2 GPC3 GLI2 IGDCC4

1.99e-06177525cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

NES MAGEL2 GPC3 GLI2 IGDCC4

1.99e-06177525db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 TNXB TMEM200B IGDCC4

2.05e-06178525c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 TNXB IGDCC4

2.16e-0618052508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

HMCN2 GLI2 ADAM33 TNXB IGDCC4

2.47e-06185525fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

MAGEL2 HMCN2 GLI2 ADAM33 IGDCC4

2.68e-06188525c90669b51e1902fe7726555290c91c92a911df83
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ABLIM1 HMCN2 GPC3 ADAM33 TNXB

2.68e-06188525409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellSubstantia_nigra-Endothelial|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NES LPP TNS2 PLSCR2 EPAS1

2.75e-06189525bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ABLIM1 WT1 PLSCR2 EPAS1

2.82e-06190525f98e2d45fab7d9e16629d7f13cc2ccfb939ef4dd
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ABLIM1 WT1 PLSCR2 EPAS1

2.89e-061915255020fe6c3452e7fab57847f5043d28ebbc5aa381
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 GLI2 CACNA1G TNXB TCF7L1

2.89e-0619152524dc77ee8de01b42559f92721655f4281b114e17
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 ADAM33 TNXB

2.89e-0619152514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ABLIM1 WT1 PLSCR2 EPAS1

2.97e-0619252524d28e28a5c54ca7770f7e5ad7f4d00039e0aaf9
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

GLI2 WT1 ADAM33 TNXB IGDCC4

2.97e-06192525a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

GLI2 WT1 ADAM33 TNXB IGDCC4

3.04e-061935259ab47b360bee1d4f1092c2269e58acebe9584021
ToppCellFibroblasts|World / lung cells shred on cell class, cell subclass, sample id

GPC3 GLI2 WT1 ADAM33 TNXB

3.53e-06199525e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GLI2 WT1 ADAM33 TNXB IGDCC4

3.62e-0620052574e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellBiopsy_Other_PF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

LIF GPC3 WT1 ADAM33 TNXB

3.62e-062005250aa316b71f195ecf17ee897e307f8928a755a637
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 TNXB

1.39e-05125524b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCF7L2 GLI2 CMTM5 EPAS1

3.07e-0515352495b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LIF GLI2 ADAM33 IGDCC4

3.07e-0515352432cf4ca828d228f23366480305592f9813fed7ff
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCF7L2 GLI2 CMTM5 EPAS1

3.07e-05153524b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCF7L2 GLI2 CMTM5 EPAS1

3.07e-051535243ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LIF GLI2 ADAM33 IGDCC4

3.07e-05153524d5f5399ebbbff508c96ce7f01272716b61597ab5
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPC3 TNS2 TNXB EPAS1

3.23e-05155524d8b5145258f075b15080f8739f537f48dd22225e
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPC3 TNS2 TNXB EPAS1

3.23e-05155524ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GPC3 TNS2 TNXB EPAS1

3.23e-051555240f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIF GLI2 MYOM3 TNXB

3.56e-051595247ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

HMCN2 CMTM5 ADAM33 TNXB

3.65e-05160524d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

HMCN2 CMTM5 ADAM33 TNXB

3.65e-051605248a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

HMCN2 CMTM5 ADAM33 TNXB

3.65e-05160524c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES WT1 PLSCR2 EPAS1

3.83e-05162524465cb483f41023d6125ea147e16f404d8e8dc9bb
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGEL2 GPC3 ADAM33 TNXB

4.12e-051655244e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

PXDNL WT1 TNXB IGDCC4

4.21e-05166524bc9323de1373fdc0357e6bb46874f6c4787443a9
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic|TCGA-Mesothelium / Sample_Type by Project: Shred V9

NES C9orf40 ADAM33 TCF7L1

4.31e-051675249062577a4b7902c9a888d706589d1b05221c0fa8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPC3 TNS2 ADAM33 TBL3

4.52e-051695246ff1172da690ca17f7108f1617b255b766971a57
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES L3MBTL1 WT1 CMTM5

4.52e-0516952487116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Cst3_(Cst3)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LIF GLI2 SEC31B

4.52e-05595231b89466083bb454812e150137514300aa8228828
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Cst3_(Cst3)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LIF GLI2 SEC31B

4.52e-05595234f0bfb48c0a98487f37da31e14e64282c70d5e66
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Cst3_(Cst3)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

LIF GLI2 SEC31B

4.52e-0559523e81235f93aaf7f373d7cbd00882e32b73da29633
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 PLSCR2 TNXB

4.95e-051735243725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 PLSCR2 TNXB

4.95e-05173524ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 ADAM33 TNXB

4.95e-0517352430d67738633493d47f06ae452424382f069b6c0a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 ADAM33 TNXB

5.06e-05174524a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 ADAM33 PLSCR2

5.53e-05178524a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 TNXB

5.77e-051805249b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 LPP MYOM3 TMEM200B

5.90e-05181524429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLI2 LPP SPOCD1 TMEM200B

5.90e-05181524fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 LPP MYOM3 TMEM200B

5.90e-05181524395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PXDNL WT1 ADAM33 TNXB

6.03e-05182524d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPC3 WT1 ADAM33 PLSCR2

6.03e-051825249966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCellPND14|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INTS6L NES ADAM33 EPAS1

6.29e-051845241bfee4eb121e76a79f48b06b45f05d124fbbedba
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPC3 WT1 ADAM33 TNXB

6.29e-05184524607b55022de21ddb6a2d75e085df76df7abf6624
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 WT1 ADAM33 TNXB

6.56e-051865247c1807fca590cdccf7f5734460bac228d33964ca
ToppCellThalamus-Endothelial|Thalamus / BrainAtlas - Mouse McCarroll V32

NES TNS2 PLSCR2 EPAS1

6.56e-05186524dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

ABLIM1 HMCN2 GPC3 ADAM33

6.56e-05186524e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

HMCN2 GLI2 ADAM33 TNXB

6.69e-051875244ea486991f66c29728d127171a07b81404ec0b78
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 WT1 PLSCR2 EPAS1

6.83e-051885248a87daf2851d9404df7c36f279db599574b47c69
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 WT1 PLSCR2 EPAS1

6.83e-051885240f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES WT1 PLSCR2 EPAS1

6.83e-05188524e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellFrontal_cortex-Endothelial|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NES TNS2 PLSCR2 EPAS1

6.83e-05188524a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES WT1 PLSCR2 EPAS1

6.83e-05188524ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES WT1 PLSCR2 EPAS1

6.83e-051885240fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCellEndothelial-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

NES MYOM3 TNXB EPAS1

6.83e-051885240824d567356d360fd8e78e840c30529c139f98a1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 GLI2 ADAM33 TNXB

6.83e-05188524ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABLIM1 WT1 PLSCR2 EPAS1

6.83e-05188524aec7485f1a9412bd3a62b70c801cb7f8dcca232d
ToppCellGlobus_pallidus-Endothelial|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NES TNS2 PLSCR2 EPAS1

6.98e-05189524ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPC3 GLI2 WT1 TNS2

6.98e-05189524c734e5693808a0333139e87bd5be2597a9252afe
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIF GPC3 WT1 CACNA1G

6.98e-05189524319e42f6e2322208de78bc666fb2c074707eb4da
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES ABLIM1 LPP EPAS1

7.12e-05190524d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 GLI2 ADAM33 TNXB

7.12e-05190524efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellfacs-Heart-LA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ABLIM1 PLSCR2 EPAS1

7.12e-05190524911b93c4c828ef2d867b91a5eced2dc12a1baf27
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MID1IP1 GPC3 WT1 CACNA1G

7.12e-05190524050d6e0546954675b6adbfecb67854b1e09739d1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPC3 ASS1 WT1 ADAM33

7.12e-051905244f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIF GPC3 WT1 TNXB

7.27e-05191524f5ce33af56178333730be308253943c54a0724cf
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 IGDCC4

7.27e-05191524b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 IGDCC4

7.41e-05192524dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCelldroplet-Heart|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES WT1 PLSCR2 EPAS1

7.41e-0519252467a7e07a11091120edbccf739836235c422ec9c6
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HMCN2 ADAM33 TNXB IGDCC4

7.41e-051925248d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIF GPC3 WT1 TNXB

7.41e-05192524a8b7c539dc3037071bf068f372e4215563e11de4
ToppCellfacs-Thymus-Epithelium-24m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES TNS2 PLSCR2 EPAS1

7.41e-0519252439afea574725ce0c67afdd79facdb34f819a828d
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN2 GPC3 CACNA1G TNXB

7.41e-05192524cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES TNS2 PLSCR2 EPAS1

7.41e-05192524597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN2 GPC3 CACNA1G TNXB

7.41e-0519252429bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

GLI2 ADAM33 TNXB IGDCC4

7.41e-05192524d21f0f577156f17c899b08871046a26b88aea011
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES TNS2 PLSCR2 EPAS1

7.41e-05192524bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIF GPC3 WT1 TNXB

7.41e-051925242143e1fad2e88b90d668e12af37b2092d379090f
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LIF GPC3 WT1 TNXB

7.41e-05192524904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 IGDCC4

7.41e-05192524deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LIF ASS1 SPOCD1 EPAS1

7.56e-05193524a313541cedfcff8fb311b9bc60157359aa103830
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES HMCN2 TNS2 EPAS1

7.56e-05193524cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

GPC3 GLI2 ADAM33 TNXB

7.56e-05193524ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 IGDCC4

7.72e-0519452460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPC3 GLI2 TNXB IGDCC4

7.72e-051945245594f7437448cb4b37d2d100f44d30c4a367df26
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPC3 PXDNL GLI2 IGDCC4

7.72e-0519452489b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 WT1 TNXB TCF7L1

7.72e-05194524f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCellfacs-MAT-Fat-18m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 WT1 TNXB TCF7L1

7.72e-05194524944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC3 WT1 TNXB TCF7L1

7.72e-0519452485081d255fcc1e9854c0073321dd9f0feaa48866
DiseaseWILMS TUMOR 1

GPC3 WT1

4.37e-056512194070
DiseaseWilms tumor 1

GPC3 WT1

4.37e-056512cv:CN033288
DiseaseNephroblastoma

GPC3 WT1

8.15e-058512cv:C0027708
DiseaseHereditary Wilms tumor

GPC3 WT1

8.15e-058512cv:C0677779
DiseaseKidney Wilms tumor

GPC3 WT1

8.15e-058512cv:CN305775
Diseasenephroblastoma (is_implicated_in)

GPC3 WT1

2.63e-0414512DOID:2154 (is_implicated_in)
Diseasecutaneous Leishmaniasis

TCF7L2 PXDNL

3.46e-0416512EFO_0005046
DiseaseHodgkins lymphoma

LPP CDCP2 TCF7L1

3.91e-0482513EFO_0000183
Diseasecitrulline measurement

HMCN2 ASS1

5.46e-0420512EFO_0009777
Diseaseurate measurement, bone density

TCF7L2 GLI2 LPP ASS1 TNXB TCF7L1

6.72e-04619516EFO_0003923, EFO_0004531
DiseaseBilateral Wilms Tumor

GPC3 WT1

1.15e-0329512C2930471
DiseaseNephroblastoma

GPC3 WT1

1.78e-0336512C0027708
Diseaseplatelet component distribution width

U2SURP LPP ADAM33 TNXB TCF7L1 EPAS1

1.86e-03755516EFO_0007984

Protein segments in the cluster

PeptideGeneStartEntry
PDPPLHFGPTKWAVG

EPAS1

641

Q99814
TDHWPGPPSFAVVGP

ABLIM1

566

O14639
CGKVPPPPFTSSWHV

CDCP2

106

Q5VXM1
PGQPVTPHWVLDGQP

ADAM33

36

Q9BZ11
TPHTTINWGPLEPPK

ARHGEF7

631

Q14155
QHGIPIPVTPKNPWS

ASS1

166

P00966
VVSWQPPPHPTQISG

IGDCC4

646

Q8TDY8
AHPWETQPVPGLPIH

ISX

206

Q2M1V0
PNSKTGVPVGHWPIP

INTS6L

276

Q5JSJ4
RPNPKTGVPIGHWPV

INTS6

271

Q9UL03
TNPGHWGSHPESPPK

KCTD19

596

Q17RG1
IEWGVLHQPPPPAGS

MID1IP1

101

Q9NPA3
HCPSIIWQAPKGQPP

MAGEL2

581

Q9UJ55
IWQAPKGQPPVPHEI

MAGEL2

586

Q9UJ55
QPGLKWVPETPVPGS

GPC3

46

P51654
PPPDVSWFKGHQPVS

HMCN2

1921

Q8NDA2
HWKHGAGSPLPITPV

LIF

16

P15018
QEPHVWGQTTPKPGK

GDF3

151

Q9NR23
PPGVPVGYVTQTWHP

PLSCR2

186

Q9NRY7
SLIPHQIPGNGGPWK

PNMA6E

76

A0A0J9YXQ4
PAGWCSKTGHPLQPP

L3MBTL1

571

Q9Y468
VIPNPPPDHWALVSG

PDE6A

331

P16499
VWIPGEGHPESPEPK

NES

1006

P48681
WLPPKSTGEPLGHVP

LPP

6

Q93052
HWGVTFTGLQPPPRK

MICAL1

176

Q8TDZ2
WAGPTPHTRNTKLPP

GLI2

746

P10070
PIVPLEKAWPGPHGT

NUTM1

171

Q86Y26
PPPVIVWTKTGGQLP

PXDNL

446

A1KZ92
SQTPAVGPWGPPGKE

FCAMR

421

Q8WWV6
HSAPTWGTIPKLPPP

CACNA1G

2106

O43497
WQKGPNPPGTLGHTV

CUL9

1901

Q8IWT3
PPLWIRPPGVAHAGQ

C9orf40

31

Q8IXQ3
HPQQTWPPVNEGPPK

PPP1R13L

441

Q8WUF5
WPQGVPQLASPAPGH

MUC3B

56

Q9H195
PPEFHPGVPWKGLQN

TNRC6C

1386

Q9HCJ0
LPPPWGPRTQTGHVI

TMEM200B

231

Q69YZ2
GIPPSGLPQVWSPVE

FER1L5

921

A0AVI2
VSPVSPPQHWPKTSG

SPATA31A6

1311

Q5VVP1
VQVPNPVGFPGTWPL

SEC31B

896

Q9NQW1
TGILTPHPGPQDSWK

SEC31B

981

Q9NQW1
GWGKAVPIPPHPIYI

U2SURP

351

O15042
HSAKVQPQPWPGLTP

CMTM5

111

Q96DZ9
PVPDENGHIPGWVPV

C12orf29

131

Q8N999
VGPNAHKVPPPWLIA

SF3B2

621

Q13435
PHLVPHPGGPEAEVW

TTBK1

386

Q5TCY1
LSPGAVGQIPHPLGW

TCF7L1

236

Q9HCS4
RQPHPEQEGWPPGTG

PLEKHG4B

166

Q96PX9
PVPAAAPTPWETHKG

TBL3

791

Q12788
NVPLKGTPPPGGAWQ

SPOCD1

1056

Q6ZMY3
PGTPPHLGNLWVTDP

TNXB

1156

P22105
SPGTVGQIPHPLGWL

TCF7L2

246

Q9NQB0
PPPHSFIKQEPSWGG

WT1

66

P19544
LHRPQPTWPPGAQQG

UBALD2

136

Q8IYN6
GIPVTTPGPFTVPWQ

PIGO

876

Q8TEQ8
PTTLPGLRHAPWQGP

TNS2

1006

Q63HR2
EQWKPVTPGPISGTH

MYOM3

846

Q5VTT5