| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyCellularComponent | microtubule associated complex | 1.07e-04 | 161 | 61 | 5 | GO:0005875 | |
| GeneOntologyCellularComponent | intercellular bridge | 1.64e-04 | 94 | 61 | 4 | GO:0045171 | |
| GeneOntologyCellularComponent | centrosome | 3.71e-04 | 770 | 61 | 9 | GO:0005813 | |
| GeneOntologyCellularComponent | cleavage furrow | 7.54e-04 | 61 | 61 | 3 | GO:0032154 | |
| HumanPheno | Macrozoospermia | 1.05e-05 | 2 | 17 | 2 | HP:0025437 | |
| Domain | DH_1 | 5.66e-05 | 63 | 62 | 4 | PS00741 | |
| Domain | RhoGEF | 8.57e-05 | 70 | 62 | 4 | PF00621 | |
| Domain | DH_2 | 8.57e-05 | 70 | 62 | 4 | PS50010 | |
| Domain | DH-domain | 9.06e-05 | 71 | 62 | 4 | IPR000219 | |
| Domain | - | 9.06e-05 | 71 | 62 | 4 | 1.20.900.10 | |
| Domain | AAA+_ATPase | 1.34e-03 | 144 | 62 | 4 | IPR003593 | |
| Domain | AAA | 1.34e-03 | 144 | 62 | 4 | SM00382 | |
| Domain | RhoGEF | 1.50e-03 | 68 | 62 | 3 | SM00325 | |
| Domain | Fibrinogen_CS | 1.79e-03 | 19 | 62 | 2 | IPR020837 | |
| Domain | P-loop_NTPase | 1.84e-03 | 848 | 62 | 9 | IPR027417 | |
| Domain | Leu-rich_rpt | 2.04e-03 | 271 | 62 | 5 | IPR001611 | |
| Domain | CRAL_TRIO | 2.19e-03 | 21 | 62 | 2 | PF00650 | |
| Domain | PH | 2.28e-03 | 278 | 62 | 5 | SM00233 | |
| Domain | PH_DOMAIN | 2.32e-03 | 279 | 62 | 5 | PS50003 | |
| Domain | PH_domain | 2.35e-03 | 280 | 62 | 5 | IPR001849 | |
| Domain | LRR_8 | 2.50e-03 | 171 | 62 | 4 | PF13855 | |
| Domain | - | 2.62e-03 | 23 | 62 | 2 | 3.40.525.10 | |
| Domain | Spectrin | 2.62e-03 | 23 | 62 | 2 | PF00435 | |
| Domain | Leu-rich_rpt_typical-subtyp | 2.84e-03 | 177 | 62 | 4 | IPR003591 | |
| Domain | LRR_TYP | 2.84e-03 | 177 | 62 | 4 | SM00369 | |
| Domain | Fibrinogen_a/b/g_C_2 | 2.85e-03 | 24 | 62 | 2 | IPR014715 | |
| Domain | - | 2.85e-03 | 24 | 62 | 2 | 4.10.530.10 | |
| Domain | SEC14 | 3.10e-03 | 25 | 62 | 2 | SM00516 | |
| Domain | CRAL_TRIO | 3.61e-03 | 27 | 62 | 2 | PS50191 | |
| Domain | Fibrinogen_C | 3.61e-03 | 27 | 62 | 2 | PF00147 | |
| Domain | CRAL-TRIO_dom | 3.88e-03 | 28 | 62 | 2 | IPR001251 | |
| Domain | FBG | 4.16e-03 | 29 | 62 | 2 | SM00186 | |
| Domain | Spectrin_repeat | 4.16e-03 | 29 | 62 | 2 | IPR002017 | |
| Domain | - | 4.23e-03 | 321 | 62 | 5 | 3.80.10.10 | |
| Domain | - | 4.44e-03 | 30 | 62 | 2 | 3.90.215.10 | |
| Domain | Fibrinogen_a/b/g_C_1 | 4.44e-03 | 30 | 62 | 2 | IPR014716 | |
| Domain | L_dom-like | 4.63e-03 | 328 | 62 | 5 | IPR032675 | |
| Domain | RA | 4.74e-03 | 31 | 62 | 2 | SM00314 | |
| Domain | Spectrin/alpha-actinin | 5.04e-03 | 32 | 62 | 2 | IPR018159 | |
| Domain | FIBRINOGEN_C_1 | 5.04e-03 | 32 | 62 | 2 | PS00514 | |
| Domain | Fibrinogen_a/b/g_C_dom | 5.04e-03 | 32 | 62 | 2 | IPR002181 | |
| Domain | FIBRINOGEN_C_2 | 5.04e-03 | 32 | 62 | 2 | PS51406 | |
| Domain | SPEC | 5.04e-03 | 32 | 62 | 2 | SM00150 | |
| Domain | ARM-type_fold | 5.31e-03 | 339 | 62 | 5 | IPR016024 | |
| Domain | LRR_1 | 6.03e-03 | 219 | 62 | 4 | PF00560 | |
| Domain | - | 6.33e-03 | 222 | 62 | 4 | 1.25.10.10 | |
| Domain | RA | 6.35e-03 | 36 | 62 | 2 | PF00788 | |
| Pathway | REACTOME_RHOA_GTPASE_CYCLE | 7.66e-05 | 149 | 42 | 5 | M41805 | |
| Pubmed | 5.65e-08 | 5 | 63 | 3 | 26954557 | ||
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 22267746 | ||
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 9722614 | ||
| Pubmed | Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP. | 3.23e-06 | 2 | 63 | 2 | 26858404 | |
| Pubmed | LARGE2 FAM184B RAPGEF6 VILL SUN1 CCNL1 BOP1 DEDD DCTN1 SERTAD3 RAB11FIP3 | 3.58e-06 | 1084 | 63 | 11 | 11544199 | |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 31801062 | ||
| Pubmed | Study on the Prognostic Values of Dynactin Genes in Low-Grade Glioma. | 1.93e-05 | 4 | 63 | 2 | 33896271 | |
| Pubmed | 2.22e-05 | 30 | 63 | 3 | 38310234 | ||
| Pubmed | A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1. | 3.22e-05 | 5 | 63 | 2 | 10671518 | |
| Pubmed | Assembly of high order G alpha q-effector complexes with RGS proteins. | 3.22e-05 | 5 | 63 | 2 | 18936096 | |
| Pubmed | Biological characterization of angiopoietin-3 and angiopoietin-4. | 4.82e-05 | 6 | 63 | 2 | 15284220 | |
| Pubmed | A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. | 5.75e-05 | 41 | 63 | 3 | 23509962 | |
| Pubmed | Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes. | 6.74e-05 | 7 | 63 | 2 | 24589552 | |
| Pubmed | The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis. | 1.15e-04 | 9 | 63 | 2 | 24413433 | |
| Pubmed | 1.44e-04 | 10 | 63 | 2 | 35794642 | ||
| Pubmed | 1.46e-04 | 146 | 63 | 4 | 21399614 | ||
| Pubmed | 1.76e-04 | 11 | 63 | 2 | 22826121 | ||
| Pubmed | 2.49e-04 | 13 | 63 | 2 | 21177258 | ||
| Pubmed | 2.90e-04 | 14 | 63 | 2 | 19874786 | ||
| Pubmed | 3.81e-04 | 16 | 63 | 2 | 29859889 | ||
| Pubmed | Genetic predictors of fibrin D-dimer levels in healthy adults. | 3.81e-04 | 16 | 63 | 2 | 21502573 | |
| Pubmed | LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy. | 5.03e-04 | 202 | 63 | 4 | 33005030 | |
| Pubmed | Constraint and divergence of global gene expression in the mammalian embryo. | 5.41e-04 | 19 | 63 | 2 | 25871848 | |
| Pubmed | 7.62e-04 | 98 | 63 | 3 | 34943047 | ||
| Pubmed | Proximity interactions among centrosome components identify regulators of centriole duplication. | 8.32e-04 | 101 | 63 | 3 | 24613305 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | 8.34e-04 | 1105 | 63 | 8 | 35748872 | |
| Pubmed | CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI. | 9.05e-04 | 104 | 63 | 3 | 31240132 | |
| Pubmed | 1.02e-03 | 26 | 63 | 2 | 28720576 | ||
| Pubmed | PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase. | 1.06e-03 | 247 | 63 | 4 | 32989298 | |
| Pubmed | Genome-wide association study of smoking behaviours in patients with COPD. | 1.27e-03 | 29 | 63 | 2 | 21685187 | |
| Pubmed | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 1.36e-03 | 30 | 63 | 2 | 20080650 | |
| Pubmed | Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. | 1.39e-03 | 1489 | 63 | 9 | 28611215 | |
| Pubmed | 1.45e-03 | 31 | 63 | 2 | 26618355 | ||
| Pubmed | Insights into the ubiquitin-proteasome system of human embryonic stem cells. | 1.46e-03 | 269 | 63 | 4 | 29511261 | |
| Pubmed | Biochemical and computational analysis of LNX1 interacting proteins. | 1.55e-03 | 32 | 63 | 2 | 22087225 | |
| Pubmed | A SOX17-PDGFB signaling axis regulates aortic root development. | 1.75e-03 | 34 | 63 | 2 | 35831318 | |
| Pubmed | 1.76e-03 | 131 | 63 | 3 | 28031328 | ||
| GeneFamily | Dynactin | 9.44e-05 | 6 | 46 | 2 | 943 | |
| GeneFamily | Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing | 6.30e-04 | 66 | 46 | 3 | 722 | |
| GeneFamily | Fibrinogen C domain containing | 1.83e-03 | 25 | 46 | 2 | 554 | |
| GeneFamily | Blood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing | 7.95e-03 | 161 | 46 | 3 | 593 | |
| GeneFamily | Zinc fingers C2H2-type|ZF class homeoboxes and pseudogenes | 9.30e-03 | 718 | 46 | 6 | 28 | |
| ToppCell | 10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue | 2.81e-06 | 156 | 63 | 5 | 1545169694f686d28648a68b552c2ae606599d66 | |
| ToppCell | 3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue | 4.40e-06 | 171 | 63 | 5 | 2e9a20f8980b78325c52065a9c14ab3656267c05 | |
| ToppCell | droplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.96e-06 | 182 | 63 | 5 | 9edaccf1154cec92ca9a28e9b1f9075cfd422bfd | |
| ToppCell | droplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 5.96e-06 | 182 | 63 | 5 | aba4c06d5d7618ac21b2695bca8e7a1346a91090 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.28e-06 | 184 | 63 | 5 | ea7a7e2bac46d4d2c31a5d576b38a032b5335062 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.28e-06 | 184 | 63 | 5 | 2cbed6462fea2622871bb7e49b0df3d984239281 | |
| ToppCell | facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 6.28e-06 | 184 | 63 | 5 | 2b19a8c5f823e00812908b23e66bb4e563278aff | |
| ToppCell | 10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue | 7.72e-06 | 192 | 63 | 5 | 47646d7e4990be85072987f92bf18d52f8da752e | |
| Disease | synucleinopathy (biomarker_via_orthology) | 2.52e-05 | 4 | 61 | 2 | DOID:0050890 (biomarker_via_orthology) | |
| Disease | neuroblastoma | 9.95e-05 | 116 | 61 | 4 | EFO_0000621 | |
| Disease | lifestyle measurement, systolic blood pressure | 1.50e-04 | 9 | 61 | 2 | EFO_0006335, EFO_0010724 | |
| Disease | visuospatial function measurement | 1.32e-03 | 26 | 61 | 2 | EFO_0803533 | |
| Disease | brain cancer (implicated_via_orthology) | 1.32e-03 | 26 | 61 | 2 | DOID:1319 (implicated_via_orthology) | |
| Disease | D dimer measurement | 1.76e-03 | 30 | 61 | 2 | EFO_0004507 | |
| Disease | central nervous system cancer | 1.88e-03 | 31 | 61 | 2 | EFO_0000326 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| QGHTQVLIHQLSRRR | 556 | Q14137 | |
| HQLRREIEIQAHLQH | 86 | Q9UQB9 | |
| IHQLVRLSNLHVQQQ | 766 | Q8TER5 | |
| QQRHLEKQHLRIQHL | 126 | Q9BY76 | |
| RLVLTQEQLHQLHSR | 1261 | Q14203 | |
| VLQHVQALLVKRFQH | 1351 | P78363 | |
| QQLLNRIQRHHTFLE | 846 | Q8NEN0 | |
| LQAQVEIKRRRHHLQ | 71 | Q8N2C3 | |
| QHVQHQLHVILKELR | 371 | Q53EZ4 | |
| NFRQVLQLLRIITRH | 81 | O75618 | |
| IRDVINVFHHLRQLR | 146 | Q9UK58 | |
| RNAQRKHILAAHQII | 716 | Q7Z4T9 | |
| DIQHILERLHRAQLQ | 91 | O95072 | |
| RDHIINALQEVRIRH | 1011 | Q6ZP01 | |
| QHSRLRQENLQLVHR | 486 | O75154 | |
| RQQQLTVHRVHVTFL | 406 | Q8N3Y3 | |
| QLLLHRSLQSIQVAH | 776 | O75747 | |
| HIEIHRLVLQQQEGL | 1396 | Q8N1W1 | |
| TARHQIIVQLLSQHN | 656 | Q5HY92 | |
| HLQEAVRQHVAQIRQ | 1816 | Q14667 | |
| EIQLLHNLRILNVSH | 206 | A4D1F6 | |
| QLHVRHVAIEQLLKN | 261 | Q9NYK6 | |
| SLVVLHLHNNRIQHL | 211 | Q9HBX8 | |
| LHQGIQRRITVTIIH | 1286 | O60333 | |
| HSLQIQHQTHRLELQ | 691 | Q9ULE4 | |
| QIQNAILHLFTTHRI | 296 | Q9H339 | |
| QHRKVRLHQRLQLCV | 526 | O60229 | |
| KVSQLIHHLLNRLQV | 96 | Q6AI08 | |
| IHHLLNRLQVIVDEQ | 101 | Q6AI08 | |
| HLEILQLSRNHIRTI | 101 | Q9HCJ2 | |
| QVLQRQILHLEQLHH | 211 | Q96M63 | |
| TLHQLNQILRHRLVT | 191 | O60244 | |
| HLAVERQHTQIVRLL | 671 | Q86YT6 | |
| RVREQLHLLKQQLRH | 131 | Q3B8N5 | |
| QVHNSTLRHRVVLVN | 571 | Q9BXP8 | |
| EHAARLQRLAQIHIQ | 121 | O75935 | |
| LRAQQLHHRVLTLQC | 16 | Q6ZRC1 | |
| LHHRVLTLQCQLRDQ | 21 | Q6ZRC1 | |
| LGQNRNREIVEHVIH | 191 | A2RU49 | |
| RIRLQHQVKRHNLIV | 1366 | O14981 | |
| IEREVSILRQVLHHN | 71 | Q9UIK4 | |
| SILRQVLHHNVITLH | 76 | Q9UIK4 | |
| HSLRQLLVLLRHLVQ | 256 | Q9Y264 | |
| GIAIQNHLQRQIREH | 706 | Q6ZVF9 | |
| IHQLQLIEQIRHQIL | 241 | Q9NSC2 | |
| GHLEQLQVLTLRHNR | 96 | Q8WUT4 | |
| QLHQHVQQLHLGTRL | 131 | Q9BPW5 | |
| HRVSQVLQVPAVNLH | 1176 | Q8TEU7 | |
| VLVIAHRLQTVQRAH | 656 | Q03519 | |
| HRLQTVQRAHQILVL | 661 | Q03519 | |
| SLTIHTIQLIQHNRR | 61 | O94864 | |
| SLRRHVLIHNTLQQL | 51 | Q9UJW9 | |
| VVHLVLRRLLQEQHQ | 4641 | Q63HN8 | |
| LLQHQRIHTREQLCE | 516 | Q6P9A3 | |
| RVRQQLTLHQRIHTG | 336 | Q9Y2G7 | |
| RPQLQRQVLQHLHTV | 426 | Q96HA7 | |
| RQVLQHLHTVQLRLQ | 431 | Q96HA7 | |
| QALSLQVEQLLHHRR | 31 | P19623 | |
| RLHLQLSLHQKLVQV | 791 | Q9Y6R6 | |
| HVETNLFNIQRLLHI | 126 | O15195 | |
| SNLIVHQRRHIGENL | 761 | Q06730 | |
| NQRVLVIHHDRARLL | 331 | Q9H892 | |
| IEGHLRHLATQRQIQ | 136 | A2RUT3 | |
| HLAQQLHQIVVDRVE | 431 | Q9NS98 | |
| LRDLQLQILRNVTHH | 551 | O94901 | |
| NVRLHGQHLVQQLVL | 131 | Q9H497 | |
| RLKVLLVQHQRVHSE | 111 | Q9NSD4 | |
| RHIHQALQEAAVQLL | 431 | O95363 | |
| QHRKVRLHQRLQLCV | 556 | O75962 | |
| RQHFLHLRQASVIIQ | 1036 | B2RTY4 |