Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	Bergmann glial cell differentiation	PTPN11 ABL1 ABL2	3.88e-06	12	55	3	GO:0060020
GeneOntologyBiologicalProcess	platelet-derived growth factor receptor signaling pathway	PTPN11 ABL1 ABL2 CSPG4	3.85e-05	71	55	4	GO:0048008
GeneOntologyBiologicalProcess	DN4 thymocyte differentiation	ABL1 ABL2	4.17e-05	4	55	2	GO:1904157
GeneOntologyBiologicalProcess	positive regulation of establishment of T cell polarity	ABL1 ABL2	4.17e-05	4	55	2	GO:1903905
GeneOntologyBiologicalProcess	neuron maturation	ABL2 CSPG4 NFASC TBX6	4.53e-05	74	55	4	GO:0042551
GeneOntologyBiologicalProcess	regulation of establishment of T cell polarity	ABL1 ABL2	1.04e-04	6	55	2	GO:1903903
Domain	VWC	FCGBP CHRDL2 CHRDL1 SSPOP	4.61e-06	38	55	4	SM00214
Domain	VWF_dom	FCGBP CHRDL2 CHRDL1 SSPOP	6.93e-06	42	55	4	IPR001007
Domain	FABD	ABL1 ABL2	8.51e-06	2	55	2	SM00808
Domain	F_actin_bind	ABL1 ABL2	8.51e-06	2	55	2	PF08919
Domain	F-actin_binding	ABL1 ABL2	8.51e-06	2	55	2	IPR015015
Domain	VWFC_1	CHRDL2 CHRDL1 SSPOP	1.61e-04	36	55	3	PS01208
Domain	VWFC_2	CHRDL2 CHRDL1 SSPOP	1.89e-04	38	55	3	PS50184
Domain	SH2	PTPN11 ABL1 ABL2 SLA2	2.22e-04	101	55	4	PF00017
Domain	SH2	PTPN11 ABL1 ABL2 SLA2	3.08e-04	110	55	4	SM00252
Domain	SH2	PTPN11 ABL1 ABL2 SLA2	3.19e-04	111	55	4	PS50001
Domain	SH2	PTPN11 ABL1 ABL2 SLA2	3.30e-04	112	55	4	IPR000980
Domain	-	PTPN11 ABL1 ABL2 SLA2	3.30e-04	112	55	4	3.30.505.10
Domain	TIL	FCGBP SSPOP	5.51e-04	12	55	2	PF01826
Domain	C8	FCGBP SSPOP	5.51e-04	12	55	2	PF08742
Domain	-	ETFDH IL4I1 SDHA	6.00e-04	56	55	3	3.50.50.60
Domain	FAD/NAD-binding_dom	ETFDH IL4I1 SDHA	6.32e-04	57	55	3	IPR023753
Domain	Unchr_dom_Cys-rich	FCGBP SSPOP	6.50e-04	13	55	2	IPR014853
Domain	C8	FCGBP SSPOP	6.50e-04	13	55	2	SM00832
Domain	TIL_dom	FCGBP SSPOP	7.57e-04	14	55	2	IPR002919
Domain	VWD	FCGBP SSPOP	9.95e-04	16	55	2	SM00216
Domain	VWF_type-D	FCGBP SSPOP	9.95e-04	16	55	2	IPR001846
Domain	VWFD	FCGBP SSPOP	9.95e-04	16	55	2	PS51233
Domain	VWD	FCGBP SSPOP	9.95e-04	16	55	2	PF00094
Domain	VWC_out	FCGBP SSPOP	1.41e-03	19	55	2	SM00215
Domain	-	PAPPA2 CSPG4 WDFY3	2.76e-03	95	55	3	2.60.120.200
Domain	VWC	CHRDL2 CHRDL1	3.06e-03	28	55	2	PF00093
Domain	Myb_DNA-binding	NCOR1 SNAPC4	4.76e-03	35	55	2	PF00249
Domain	MYB_LIKE	NCOR1 SNAPC4	5.59e-03	38	55	2	PS50090
Pathway	KEGG_MEDICUS_ENV_FACTOR_METALS_TO_NFKB_SIGNALING_PATHWAY	PTPN11 ABL1 ABL2	1.09e-05	15	42	3	M47816
Pubmed	SHP-2 is a novel target of Abl kinases during cell proliferation.	PTPN11 ABL1 ABL2	1.67e-08	4	57	3	18827006
Pubmed	Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases.	ABL1 ABL2	2.64e-06	2	57	2	15987940
Pubmed	c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3.	ABL1 ABL2	2.64e-06	2	57	2	20150913
Pubmed	The Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infection.	ABL1 ABL2	2.64e-06	2	57	2	22665498
Pubmed	Global Regulation of Differential Gene Expression by c-Abl/Arg Oncogenic Kinases.	ABL1 ABL2	2.64e-06	2	57	2	28555614
Pubmed	The expression of the non-receptor tyrosine kinases Arg and c-abl is differently modulated in B lymphoid cells at different stages of differentiation.	ABL1 ABL2	2.64e-06	2	57	2	12220663
Pubmed	Loss of dendrite stabilization by the Abl-related gene (Arg) kinase regulates behavioral flexibility and sensitivity to cocaine.	ABL1 ABL2	2.64e-06	2	57	2	19805386
Pubmed	c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion via distinct pathways, and drive metastatic progression.	ABL1 ABL2	2.64e-06	2	57	2	21892207
Pubmed	Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes.	ABL1 ABL2	2.64e-06	2	57	2	11279004
Pubmed	Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin.	ABL1 ABL2	2.64e-06	2	57	2	17686996
Pubmed	ABL tyrosine kinases: evolution of function, regulation, and specificity.	ABL1 ABL2	2.64e-06	2	57	2	20841568
Pubmed	Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling.	ABL1 ABL2	2.64e-06	2	57	2	33122628
Pubmed	Dystrophic epidermolysis bullosa pruriginosa: a new case series of a rare phenotype unveils skewed Th2 immunity.	COL7A1 FLG2	2.64e-06	2	57	2	34543471
Pubmed	Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus.	ABL1 ABL2	2.64e-06	2	57	2	20181697
Pubmed	Abl family nonreceptor tyrosine kinases modulate short-term synaptic plasticity.	ABL1 ABL2	2.64e-06	2	57	2	12626632
Pubmed	The Abl family kinases: mechanisms of regulation and signaling.	ABL1 ABL2	2.64e-06	2	57	2	12374288
Pubmed	Defective T cell development and function in the absence of Abelson kinases.	ABL1 ABL2	2.64e-06	2	57	2	18025176
Pubmed	Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.	PTPN11 ABL1 ABL2 SLA2	6.48e-06	73	57	4	24728074
Pubmed	Two distinct phosphorylation pathways have additive effects on Abl family kinase activation.	ABL1 ABL2	7.91e-06	3	57	2	12748290
Pubmed	Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages.	ABL1 ABL2	7.91e-06	3	57	2	23100514
Pubmed	Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment.	ABL1 ABL2	7.91e-06	3	57	2	22738912
Pubmed	ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks.	ABL1 ABL2	7.91e-06	3	57	2	9211900
Pubmed	Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.	PTPN11 ABL1	7.91e-06	3	57	2	23980151
Pubmed	Ubiquitination and degradation of the Arg tyrosine kinase is regulated by oxidative stress.	ABL1 ABL2	7.91e-06	3	57	2	15735735
Pubmed	Arg kinase regulates prefrontal dendritic spine refinement and cocaine-induced plasticity.	ABL1 ABL2	7.91e-06	3	57	2	22396406
Pubmed	Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response.	ABL1 ABL2	7.91e-06	3	57	2	12569093
Pubmed	Catalase is regulated by ubiquitination and proteosomal degradation. Role of the c-Abl and Arg tyrosine kinases.	ABL1 ABL2	7.91e-06	3	57	2	12950161
Pubmed	Non-receptor tyrosine kinases c-Abl and Arg regulate the activity of C/EBPbeta.	ABL1 ABL2	7.91e-06	3	57	2	19563810
Pubmed	Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases.	ABL1 ABL2	7.91e-06	3	57	2	12893824
Pubmed	Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation.	ABL1 ABL2	7.91e-06	3	57	2	9774693
Pubmed	ShcA regulates thymocyte proliferation through specific transcription factors and a c-Abl-dependent signaling axis.	ABL1 ABL2	7.91e-06	3	57	2	25691660
Pubmed	Catalase activity is regulated by c-Abl and Arg in the oxidative stress response.	ABL1 ABL2	7.91e-06	3	57	2	12777400
Pubmed	Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.	PTPN11 ABL1 ABL2 SLA2	8.02e-06	77	57	4	22973453
Pubmed	A quantitative protein interaction network for the ErbB receptors using protein microarrays.	PTPN11 ABL1 ABL2 SLA2	1.49e-05	90	57	4	16273093
Pubmed	Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1.	ABL1 ABL2	1.58e-05	4	57	2	22810897
Pubmed	Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.	ABL1 ABL2	1.58e-05	4	57	2	10995551
Pubmed	Arg interacts with cortactin to promote adhesion-dependent cell edge protrusion.	ABL1 ABL2	1.58e-05	4	57	2	19414610
Pubmed	Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies.	ABL1 ABL2	1.58e-05	4	57	2	29988075
Pubmed	c-Abl kinase regulates the protein binding activity of c-Crk.	ABL1 ABL2	1.58e-05	4	57	2	8194526
Pubmed	Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor.	ABL1 ABL2	1.58e-05	4	57	2	14993293
Pubmed	Reciprocal regulation of Abl and receptor tyrosine kinases.	ABL1 ABL2	1.58e-05	4	57	2	19275932
Pubmed	Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation.	ABL1 ABL2	1.58e-05	4	57	2	20837657
Pubmed	Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.	PTPN11 ABL1 ABL2	1.64e-05	30	57	3	12522270
Pubmed	SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.	PTPN11 ABL1 ABL2	2.00e-05	32	57	3	22974441
Pubmed	Interaction between c-Abl and Arg tyrosine kinases and proteasome subunit PSMA7 regulates proteasome degradation.	ABL1 ABL2	2.63e-05	5	57	2	16678104
Pubmed	Proline-rich sequences mediate the interaction of the Arg protein tyrosine kinase with Crk.	ABL1 ABL2	2.63e-05	5	57	2	8875975
Pubmed	TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy.	WDFY3 NBR1	2.63e-05	5	57	2	24128730
Pubmed	The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.	PTPN11 ABL1	2.63e-05	5	57	2	9393882
Pubmed	Sphingosine 1-phosphate induces membrane ruffling and increases motility of human umbilical vein endothelial cells via vascular endothelial growth factor receptor and CrkII.	ABL1 ABL2	2.63e-05	5	57	2	11956190
Pubmed	c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesis.	ABL1 ABL2	2.63e-05	5	57	2	20417104
Pubmed	Timely Inhibitory Circuit Formation Controlled by Abl1 Regulates Innate Olfactory Behaviors in Mouse.	ABL1 ABL2	2.63e-05	5	57	2	31914386
Pubmed	Essential roles for the Abl and Arg tyrosine kinases in neurulation.	ABL1 ABL2	2.63e-05	5	57	2	9883720
Pubmed	Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor.	ABL1 ABL2	2.63e-05	5	57	2	11494128
Pubmed	Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.	PTPN11 ABL1	2.63e-05	5	57	2	11266449
Pubmed	RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.	ABL1 ABL2	2.63e-05	5	57	2	15886098
Pubmed	Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.	NCOR1 CSPG4	3.94e-05	6	57	2	18829436
Pubmed	ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1.	ABL1 ABL2	3.94e-05	6	57	2	37040401
Pubmed	Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling.	ABL1 ABL2	3.94e-05	6	57	2	12198159
Pubmed	Inhibition of Rho via Arg and p190RhoGAP in the postnatal mouse hippocampus regulates dendritic spine maturation, synapse and dendrite stability, and behavior.	ABL1 ABL2	3.94e-05	6	57	2	17928439
Pubmed	Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes.	PTPN11 ABL1	5.51e-05	7	57	2	8879209
Pubmed	A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.	ABL1 ABL2	5.51e-05	7	57	2	1383690
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOR1 ABL1 PSME4 CSPG4 AKNA GEMIN5 WDFY3 SNAPC4 SDHA	7.29e-05	1105	57	9	35748872
Pubmed	Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation.	CHRDL2 CHRDL1	7.34e-05	8	57	2	18789316
Pubmed	Abl family kinases regulate endothelial barrier function in vitro and in mice.	ABL1 ABL2	7.34e-05	8	57	2	24367707
Pubmed	Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.	ABL1 ABL2	7.34e-05	8	57	2	10892742
Pubmed	Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase.	ABL1 ABL2	9.43e-05	9	57	2	25624478
Pubmed	A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage.	CHRDL2 CHRDL1	9.43e-05	9	57	2	14660436
Pubmed	The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.	WDFY3 NBR1	9.43e-05	9	57	2	20417604
Pubmed	ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling.	ABL1 ABL2	9.43e-05	9	57	2	28086240
Pubmed	Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival.	ABL1 ABL2	9.43e-05	9	57	2	23840065
Pubmed	microRNA-184 Induces a Commitment Switch to Epidermal Differentiation.	KRT10 FLG2	9.43e-05	9	57	2	29198823
Pubmed	The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells.	KRT10 SDHA	1.18e-04	10	57	2	21780252
Pubmed	Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.	ABL1 ABL2	1.44e-04	11	57	2	20598684
Pubmed	Eyelid closure in embryogenesis is required for ocular adnexa development.	KRT10 PTPN11	1.44e-04	11	57	2	25377219
Pubmed	HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity.	NCOR1 KRT10	1.44e-04	11	57	2	32467224
Pubmed	A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.	KRT10 FLG2 SDHA	1.47e-04	62	57	3	26644517
Pubmed	Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality.	PTPN11 CSPG4	1.72e-04	12	57	2	17646384
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	PSME4 CNDP2 NFS1 TICAM2	2.36e-04	183	57	4	31932471
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS16 SSPOP TBX6	2.59e-04	75	57	3	20637190
Pubmed	Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum.	ABL1 ABL2	2.73e-04	15	57	2	20980600
Pubmed	Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.	KRT10 PTPN11 SDHA	4.43e-04	90	57	3	31280863
Pubmed	Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.	NCOR1 JMJD1C	5.43e-04	21	57	2	19596656
Pubmed	The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.	ZNF793 ZNF84	5.97e-04	22	57	2	31403225
Pubmed	Defining the membrane proteome of NK cells.	NCOR1 KRT10 GLT8D1 PARP16 PTDSS1 AKNA GEMIN5 NBR1	6.06e-04	1168	57	8	19946888
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF793 PTDSS1 CNDP2 NFASC ZNF84 SSX2 SSPOP NBR1 JMJD1C	6.64e-04	1489	57	9	28611215
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	NCOR1 JMJD1C	7.12e-04	24	57	2	33722704
Pubmed	Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1.	ABL1 ABL2	7.12e-04	24	57	2	20624904
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	ABL1 ABL2	7.73e-04	25	57	2	15254900
Pubmed	Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.	CSPG4 NFASC	7.73e-04	25	57	2	32266943
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	KRT10 PTPN11 ABL1 ABL2	9.61e-04	266	57	4	19380743
Pubmed	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	ABL1 ABL2	9.71e-04	28	57	2	18067320
Pubmed	BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.	CHRDL2 CHRDL1	9.71e-04	28	57	2	23103586
Pubmed	JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis.	PSME4 JMJD1C	1.04e-03	29	57	2	27649575
Pubmed	Control of developmentally primed erythroid genes by combinatorial co-repressor actions.	NCOR1 JMJD1C	1.11e-03	30	57	2	26593974
Pubmed	Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor.	KRT10 FLG2	1.11e-03	30	57	2	34905516
Pubmed	Sf3b4 regulates chromatin remodeler splicing and Hox expression.	HOXC11 JMJD1C	1.27e-03	32	57	2	37167859
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZNF793 NCOR1 KRT10 PTPN11 JMJD1C	1.33e-03	497	57	5	23414517
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	ABL1 ABL2 SLA2	1.41e-03	134	57	3	24658140
Pubmed	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	PTPN11 JMJD1C	1.43e-03	34	57	2	19820697
Pubmed	In silico prediction of physical protein interactions and characterization of interactome orphans.	ABL1 ABL2 SLA2	1.47e-03	136	57	3	25402006
Cytoband	5p15	ADAMTS16 SDHA	3.17e-05	7	57	2	5p15
Cytoband	3p21.1	COL7A1 GLT8D1	1.26e-03	42	57	2	3p21.1
GeneFamily	SH2 domain containing	PTPN11 ABL1 ABL2 SLA2	7.18e-05	101	40	4	741
ToppCell	ASK454-Endothelial-Lymphatic\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	SEMA3D CHRDL2 PARP16 CHRDL1 SLA2	3.34e-06	179	57	5	fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PAPPA2 CRYBA4 IL4I1 TBX6	6.48e-06	94	57	4	d78535a7a0fda7299b01912333b944dc5e0a0361
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PAPPA2 CRYBA4 IL4I1 TBX6	6.48e-06	94	57	4	dfc3f7977b9df433009d1d2d465b64a2de5806e2
Disease	scoliosis (implicated_via_orthology)	SSPOP TBX6	3.40e-05	5	55	2	DOID:0060249 (implicated_via_orthology)
Disease	nervousness	YLPM1 ETFDH	4.03e-04	16	55	2	NCIT_C74532
Disease	idiopathic scoliosis (implicated_via_orthology)	PTPN11 SSPOP	4.03e-04	16	55	2	DOID:0060250 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	PAPPA2 COL7A1 PTPN11 YLPM1 ETFDH AKNA JMJD1C	9.65e-04	848	55	7	EFO_0004614
Disease	coffee consumption	PTPN11 YLPM1	1.63e-03	32	55	2	EFO_0004330

Protein segments in the cluster

Peptide	Gene	Start	Entry
DGWTPLHVAAHYGRD	ASB7	116	Q9H672
GDEVHYHVTAGPRWG	CSPG4	1161	Q6UVK1
NSLEKHSWYHGPVSR	ABL2	166	P42684
HDTSPYRWGGKTDID	ADGRL2	251	O95490
HWLTSYTHDFTGLGP	C7orf31	276	Q8N865
KYGDEGPKPTHGHWS	ADAMTS16	576	Q8TE57
ESHGRAHDPLYGSWQ	MFSD10	51	Q14728
DTPGHKSGYRHSSWS	FLG2	121	Q5D862
WYEKHGNSHQGEPRD	KRT10	181	P13645
GNPHSRTHAYGWESE	NFS1	86	Q9Y697
HAYSGLGLPSSKWVH	JMJD1C	871	Q15652
GHGRIDHSWLPSDKS	KIAA2012	306	Q0VF49
PGESKDLAGRLHHSW	GOLGA6L2	161	Q8N9W4
GHLKPWGRTASYTDV	GLT8D1	331	Q68CQ7
DPTSERWFHGHLSGK	PTPN11	106	Q06124
GKTYSHGEVWHPAFR	CHRDL2	256	Q6WN34
DLSLALIYSPHGHGW	PARP16	186	Q8N5Y8
HGPWISHVTRGAYLE	PRSS36	546	Q5K4E3
QPGVWHDHSKYPGSV	NFASC	671	O94856
PGTWTHVAATYDGRH	PAPPA2	361	Q9BXP8
VDHTVGWPLDRHTYG	ETFDH	291	Q16134
GSRKLEYGGQTWHEH	FHL3	111	Q13643
LHWSDLPYKGSEHSL	CA4	116	P22748
VSNGKTYSHGESWHP	CHRDL1	261	Q9BU40
WGDPHYVTLDGHRFD	FCGBP	3276	Q9Y6R7
AWGDPHYVTLDGHRF	FCGBP	4476	Q9Y6R7
RGHFLSGWHTIYLPD	FCN2	111	Q15485
SLEKHSWYHGPVSRN	ABL1	121	P00519
TWGSHYGSKSTERLP	AKNA	1126	Q7Z591
GDYKHFREWGSHAPT	CRYBA4	171	P53673
IPSVHGRTDWVAKYG	MAK	606	P20794
REVSYGLEPSGKWHH	HOXC11	71	O43248
GLEPSGKWHHRNSYS	HOXC11	76	O43248
SVEHRPGTHDSEGYW	MARCHF10	426	Q8NA82
GATGYRVSWHSAHGP	COL7A1	711	Q02388
EHTAYPHGWVETAVK	IL4I1	481	Q96RQ9
GGDAYAKWHTRPHYL	SSPOP	2111	A2VEC9
HVAKVSHGWLYEGLS	SLA2	86	Q9H6Q3
HWRKHTLSYVDVGTG	SDHA	621	P31040
LEGTYTSHWRLSHKG	NBR1	451	Q14596
VHSEGDYHRQTPGWA	NCOR1	2356	O75376
HDRWTEHHGRYPSTG	ST3GAL2	266	Q16842
WGLSTYSHGKSQPRH	SPATA31E1	316	Q6ZUB1
SWGKRHSVDTSPGYH	TICAM2	16	Q86XR7
GPYAHKESADHRWVQ	SEMA3D	371	O95025
HYGEESKRPPLFHTW	CINP	126	Q9BW66
GGKPWVSDFSHPHYL	CNDP2	381	Q96KP4
KHWRTHTGEKPYGCN	ZNF793	356	Q6ZN11
WGTPALSRKRHAYHS	WDFY3	801	Q8IZQ1
AGAYDRLSPHHWEKS	ZNF174	181	Q15697
IHERSGPKRGEHAWT	SSX2	151	Q16385
HWKVHTGARPYECGE	ZNF256	481	Q9Y2P7
AWSPHHDGRLVSASY	GEMIN5	646	Q8TEQ6
RVYIHPDSPATGAHW	TBX6	171	O95947
GDRPDNHWLHYDSKT	PSME4	1241	Q14997
RYEGHPAEGTKSKWG	YLPM1	796	P49750
GYPVHLGKAGTHWEQ	nan	601	Q3C1V9
LISHWRTHTGEKPYG	ZNF84	306	P51523
YGVGHWAKIASELPH	SNAPC4	471	Q5SXM2
LPYFRTHEWAHTGGK	ZNF625	81	Q96I27
THEWAHTGGKPYDCE	ZNF625	86	Q96I27
DGTYSPEISWHHRKG	PTDSS1	421	P48651