Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	N-acetylglucosamine-6-sulfatase activity	SULF1 GNS	4.51e-05	3	78	2	GO:0008449
GeneOntologyMolecularFunction	histone H2B deubiquitinase activity	USP49 USP22	8.99e-05	4	78	2	GO:0140936
GeneOntologyMolecularFunction	bile acid:sodium symporter activity	SLC10A2 SLC10A6	2.24e-04	6	78	2	GO:0008508
GeneOntologyMolecularFunction	histone deubiquitinase activity	USP49 USP22	4.15e-04	8	78	2	GO:0140934
GeneOntologyMolecularFunction	protein-glutamine gamma-glutamyltransferase activity	TGM7 TGM5	5.33e-04	9	78	2	GO:0003810
GeneOntologyBiologicalProcess	innervation	GABRB3 SULF1 VCAM1 EDNRA	8.47e-06	34	79	4	GO:0060384
GeneOntologyBiologicalProcess	response to histamine	GABRB1 GABRB3 DRD2	1.16e-05	12	79	3	GO:0034776
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	WDR19 RAD51B RNF220 ERCC2 CMIP USP22 SULF1 MIB1 PRAMEF12 ARHGAP35 THOC2 VCAM1 EDNRA	4.83e-05	929	79	13	GO:0009792
GeneOntologyBiologicalProcess	nerve development	GABRB3 SULF1 SCN1A VCAM1 EDNRA	6.21e-05	109	79	5	GO:0021675
GeneOntologyBiologicalProcess	cellular response to luteinizing hormone stimulus	LHCGR EDNRA	1.44e-04	5	79	2	GO:0071373
GeneOntologyBiologicalProcess	chordate embryonic development	WDR19 RAD51B RNF220 ERCC2 CMIP SULF1 MIB1 PRAMEF12 ARHGAP35 THOC2 VCAM1 EDNRA	1.63e-04	906	79	12	GO:0043009
GeneOntologyBiologicalProcess	peptidyl-tryptophan modification	DPY19L2 DPY19L1	2.15e-04	6	79	2	GO:0018211
GeneOntologyBiologicalProcess	protein C-linked glycosylation via tryptophan	DPY19L2 DPY19L1	2.15e-04	6	79	2	GO:0018317
GeneOntologyBiologicalProcess	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	DPY19L2 DPY19L1	2.15e-04	6	79	2	GO:0018406
GeneOntologyBiologicalProcess	protein C-linked glycosylation	DPY19L2 DPY19L1	2.15e-04	6	79	2	GO:0018103
GeneOntologyBiologicalProcess	luteinizing hormone signaling pathway	LHB LHCGR	3.00e-04	7	79	2	GO:0042700
GeneOntologyBiologicalProcess	regulation of inositol trisphosphate biosynthetic process	LHCGR P2RY1	3.00e-04	7	79	2	GO:0032960
GeneOntologyBiologicalProcess	positive regulation of inositol trisphosphate biosynthetic process	LHCGR P2RY1	3.00e-04	7	79	2	GO:0032962
GeneOntologyBiologicalProcess	response to luteinizing hormone	LHCGR EDNRA	3.00e-04	7	79	2	GO:0034699
GeneOntologyBiologicalProcess	cellular response to histamine	GABRB1 GABRB3	3.00e-04	7	79	2	GO:0071420
GeneOntologyBiologicalProcess	embryo development	WDR19 RAD51B RNF220 ERCC2 CMIP USP22 SULF1 MIB1 PRAMEF12 ARHGAP35 MYO15A THOC2 TRIP12 VCAM1 EDNRA	3.20e-04	1437	79	15	GO:0009790
Domain	Peptidase_M12B_N	ADAMTS2 ADAM29 ADAM2 ADAM22	2.41e-05	39	81	4	IPR002870
Domain	Pep_M12B_propep	ADAMTS2 ADAM29 ADAM2 ADAM22	2.41e-05	39	81	4	PF01562
Domain	DISINTEGRIN_1	ADAMTS2 ADAM29 ADAM2 ADAM22	2.66e-05	40	81	4	PS00427
Domain	Reprolysin	ADAMTS2 ADAM29 ADAM2 ADAM22	2.66e-05	40	81	4	PF01421
Domain	ADAM_MEPRO	ADAMTS2 ADAM29 ADAM2 ADAM22	2.66e-05	40	81	4	PS50215
Domain	DISINTEGRIN_2	ADAMTS2 ADAM29 ADAM2 ADAM22	2.66e-05	40	81	4	PS50214
Domain	Peptidase_M12B	ADAMTS2 ADAM29 ADAM2 ADAM22	2.66e-05	40	81	4	IPR001590
Domain	Disintegrin_dom	ADAMTS2 ADAM29 ADAM2 ADAM22	2.94e-05	41	81	4	IPR001762
Domain	Disintegrin_CS	ADAM29 ADAM2 ADAM22	4.23e-05	16	81	3	IPR018358
Domain	GABAAb_rcpt	GABRB1 GABRB3	5.56e-05	3	81	2	IPR002289
Domain	ADAM_CR	ADAM29 ADAM2 ADAM22	6.12e-05	18	81	3	PF08516
Domain	-	ADAM29 ADAM2 ADAM22	8.49e-05	20	81	3	4.10.70.10
Domain	Disintegrin	ADAM29 ADAM2 ADAM22	9.88e-05	21	81	3	PF00200
Domain	DISIN	ADAM29 ADAM2 ADAM22	9.88e-05	21	81	3	SM00050
Domain	LRRC37AB_C	LRRC37A LRRC37A2	1.11e-04	4	81	2	PF14914
Domain	Bilac:Na_transpt	SLC10A2 SLC10A6	1.11e-04	4	81	2	IPR004710
Domain	Dpy19	DPY19L2 DPY19L1	1.11e-04	4	81	2	PF10034
Domain	LRRC37_N	LRRC37A LRRC37A2	1.11e-04	4	81	2	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A2	1.11e-04	4	81	2	IPR029423
Domain	LRRC37	LRRC37A LRRC37A2	1.11e-04	4	81	2	PF15779
Domain	Dpy-19/Dpy-19-like	DPY19L2 DPY19L1	1.11e-04	4	81	2	IPR018732
Domain	LRRC37A/B-like	LRRC37A LRRC37A2	1.11e-04	4	81	2	IPR015753
Domain	ACR	ADAM29 ADAM2 ADAM22	2.13e-04	27	81	3	SM00608
Domain	ADAM_Cys-rich	ADAM29 ADAM2 ADAM22	2.13e-04	27	81	3	IPR006586
Domain	RhoGEF	FGD1 ECT2 FGD6 PREX1	2.17e-04	68	81	4	SM00325
Domain	RhoGEF	FGD1 ECT2 FGD6 PREX1	2.42e-04	70	81	4	PF00621
Domain	DH_2	FGD1 ECT2 FGD6 PREX1	2.42e-04	70	81	4	PS50010
Domain	DH-domain	FGD1 ECT2 FGD6 PREX1	2.56e-04	71	81	4	IPR000219
Domain	-	FGD1 ECT2 FGD6 PREX1	2.56e-04	71	81	4	1.20.900.10
Domain	FYVE	FGD1 ZFYVE26 FGD6	2.65e-04	29	81	3	PF01363
Domain	FYVE	FGD1 ZFYVE26 FGD6	2.65e-04	29	81	3	SM00064
Domain	BilAc:Na_symport/Acr3	SLC10A2 SLC10A6	3.85e-04	7	81	2	IPR002657
Domain	SBF	SLC10A2 SLC10A6	3.85e-04	7	81	2	PF01758
Domain	MetalloPept_cat_dom	ADAMTS2 ADAM29 ADAM2 ADAM22	4.24e-04	81	81	4	IPR024079
Domain	-	ADAMTS2 ADAM29 ADAM2 ADAM22	4.24e-04	81	81	4	3.40.390.10
Domain	Znf_FYVE-rel	FGD1 ZFYVE26 FGD6	4.27e-04	34	81	3	IPR017455
Domain	Znf_FYVE	FGD1 ZFYVE26 FGD6	5.94e-04	38	81	3	IPR000306
Domain	GDS_CDC24_CS	FGD1 ECT2 PREX1	6.42e-04	39	81	3	IPR001331
Domain	Transglut_N	TGM7 TGM5	6.56e-04	9	81	2	PF00868
Domain	TRANSGLUTAMINASES	TGM7 TGM5	6.56e-04	9	81	2	PS00547
Domain	Transglutaminase_N	TGM7 TGM5	6.56e-04	9	81	2	IPR001102
Domain	Transglut_C	TGM7 TGM5	6.56e-04	9	81	2	PF00927
Domain	-	TGM7 TGM5	6.56e-04	9	81	2	3.90.260.10
Domain	Gln_gamma-glutamylTfrase_euk	TGM7 TGM5	6.56e-04	9	81	2	IPR023608
Domain	Transglutaminase_AS	TGM7 TGM5	6.56e-04	9	81	2	IPR013808
Domain	ZF_FYVE	FGD1 ZFYVE26 FGD6	6.92e-04	40	81	3	PS50178
Domain	-	USP49 RNF220 USP22 MIB1 FGD1 ZFYVE26 TRIM68 FGD6	7.27e-04	449	81	8	3.30.40.10
Domain	Transglutaminase_C	TGM7 TGM5	8.17e-04	10	81	2	IPR008958
Domain	Znf_RING/FYVE/PHD	USP49 RNF220 USP22 MIB1 FGD1 ZFYVE26 TRIM68 FGD6	8.39e-04	459	81	8	IPR013083
Domain	TGc	TGM7 TGM5	9.96e-04	11	81	2	SM00460
Domain	Transglut_core	TGM7 TGM5	9.96e-04	11	81	2	PF01841
Domain	Transglutaminase-like	TGM7 TGM5	9.96e-04	11	81	2	IPR002931
Domain	Znf_UBP	USP49 USP22	1.63e-03	14	81	2	IPR001607
Domain	zf-UBP	USP49 USP22	1.63e-03	14	81	2	PF02148
Domain	ZF_UBP	USP49 USP22	1.63e-03	14	81	2	PS50271
Domain	Clathrin/coatomer_adapt-like_N	AP4E1 NCAPD2	1.88e-03	15	81	2	IPR002553
Domain	Adaptin_N	AP4E1 NCAPD2	1.88e-03	15	81	2	PF01602
Domain	Sulfatase_CS	SULF1 GNS	2.14e-03	16	81	2	IPR024607
Domain	SULFATASE_1	SULF1 GNS	2.42e-03	17	81	2	PS00523
Domain	SULFATASE_2	SULF1 GNS	2.42e-03	17	81	2	PS00149
Domain	MAM	MALRD1 EGFL6	2.42e-03	17	81	2	SM00137
Domain	DH_1	FGD1 ECT2 PREX1	2.59e-03	63	81	3	PS00741
Domain	MAM	MALRD1 EGFL6	2.72e-03	18	81	2	PF00629
Domain	Sulfatase	SULF1 GNS	2.72e-03	18	81	2	PF00884
Domain	MAM_dom	MALRD1 EGFL6	2.72e-03	18	81	2	IPR000998
Domain	MAM_2	MALRD1 EGFL6	2.72e-03	18	81	2	PS50060
Domain	Sulfatase_N	SULF1 GNS	2.72e-03	18	81	2	IPR000917
Domain	ARM-type_fold	AP4E1 UPF2 NCAPD2 FRYL MEI1 TRIP12	3.54e-03	339	81	6	IPR016024
Domain	EGF_3	MALRD1 ADAM29 ADAM2 ADAM22 EGFL6	3.56e-03	235	81	5	PS50026
Pubmed	GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.	GABRB1 GABRB3	5.63e-06	2	83	2	21735059
Pubmed	Inactivating mutations of luteinizing hormone beta-subunit or luteinizing hormone receptor cause oligo-amenorrhea and infertility in women.	LHB LHCGR	5.63e-06	2	83	2	19129711
Pubmed	Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.	GABRB1 GABRB3	5.63e-06	2	83	2	26950270
Pubmed	A receptor-binding region in human choriogonadotropin/lutropin beta subunit.	LHB LHCGR	5.63e-06	2	83	2	3470775
Pubmed	Multiple modes for conferring surface expression of homomeric beta1 GABAA receptors.	GABRB1 GABRB3	5.63e-06	2	83	2	18650446
Pubmed	Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAA receptor beta3 subunit genes.	GABRB3 DRD2	5.63e-06	2	83	2	15296817
Pubmed	A mutation in GABRB3 associated with Dravet syndrome.	GABRB3 SCN1A	5.63e-06	2	83	2	28544625
Pubmed	Association between genes encoding components of the Leutinizing hormone/Luteinizing hormone-choriogonadotrophin receptor pathway and polycystic ovary syndrome in Egyptian women.	LHB LHCGR	5.63e-06	2	83	2	26662070
Pubmed	Association of the genetic variants of luteinizing hormone, luteinizing hormone receptor and polycystic ovary syndrome.	LHB LHCGR	5.63e-06	2	83	2	22546001
Pubmed	Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis.	ARHGAP35 ECT2	5.63e-06	2	83	2	18642445
Pubmed	Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex.	DPY19L2 DPY19L1 NEUROD6	1.45e-05	20	83	3	22028030
Pubmed	RNF220 promotes the proliferation of leukaemic cells and reduces the degradation of the Cyclin D1 protein through USP22.	RNF220 USP22	1.69e-05	3	83	2	32896826
Pubmed	A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction.	DRD2 NEUROD6	1.69e-05	3	83	2	32034128
Pubmed	LH (Trp8Arg/Ile15Thr), LHR (insLQ) and FSHR (Asn680Ser) polymorphisms genotypic prevalence in women with endometriosis and infertility.	LHB LHCGR	1.69e-05	3	83	2	25935136
Pubmed	Polymorphisms of the dopamine D2 receptor, serotonin transporter, and GABA(A) receptor beta(3) subunit genes and alcoholism in Mexican-Americans.	GABRB3 DRD2	1.69e-05	3	83	2	15066703
Pubmed	A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E epsilon4 allele.	LHB LHCGR	1.69e-05	3	83	2	18439297
Pubmed	Ring finger 220 promotes the stemness and progression of colon cancer cells via Ubiquitin specific peptidase 22-BMI1 axis.	RNF220 USP22	1.69e-05	3	83	2	34753387
Pubmed	Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.	GABRB1 GABRB3	1.69e-05	3	83	2	18281286
Pubmed	GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.	GABRB1 GABRB3	1.69e-05	3	83	2	7893750
Pubmed	Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.	GABRB1 GABRB3	1.69e-05	3	83	2	11085308
Pubmed	GABAA receptor beta subunit mRNA expression in the human alcoholic brain.	GABRB1 GABRB3	1.69e-05	3	83	2	15337300
Pubmed	Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.	GABRB1 GABRB3	1.69e-05	3	83	2	1282920
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	DRD2 RYR1	3.37e-05	4	83	2	18206662
Pubmed	Association study of dopamine D2, D4 receptor gene, GABAA receptor beta subunit gene, serotonin transporter gene polymorphism with children of alcoholics in Korea: a preliminary study.	GABRB3 DRD2	3.37e-05	4	83	2	18358985
Pubmed	Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior.	ARHGAP35 NEUROD6	3.37e-05	4	83	2	22357865
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A2	3.37e-05	4	83	2	22419166
Pubmed	Identification of QTLs influencing alcohol preference in the High Alcohol Preferring (HAP) and Low Alcohol Preferring (LAP) mouse lines.	DRD2 SCN1A	3.37e-05	4	83	2	16482403
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	WDR19 CNPPD1 RNF220 SULF1 MIB1 TRIM68 KIF5C NEUROD6 TRIP12 PREX1 ADAM22 FBXW11	5.29e-05	1285	83	12	35914814
Pubmed	The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.	GABRB1 GABRB3	5.60e-05	5	83	2	15198677
Pubmed	A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABA(A) receptors by cAMP-dependent protein kinase via selective interaction with receptor beta subunits.	GABRB1 GABRB3	5.60e-05	5	83	2	12595241
Pubmed	Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.	GABRB1 GABRB3	5.60e-05	5	83	2	9039914
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRYL KIF5C DENND5A FBXW11	5.77e-05	87	83	4	12465718
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CNPPD1 JAK3 ERCC2 NCAPD2 ZFYVE26 FRYL DENND5A ARHGAP35 SPPL2B PREX1 RYR1	6.32e-05	1105	83	11	35748872
Pubmed	The role of amino acid neurotransmitters in the regulation of pituitary gonadotropin release in fish.	GABRB1 LHB	8.39e-05	6	83	2	10949077
Pubmed	USP7 Deubiquitinates and Stabilizes SIRT1.	USP22 ECT2	8.39e-05	6	83	2	31502386
Pubmed	Functional analysis of LHbeta knockout mice.	LHB LHCGR	8.39e-05	6	83	2	17350160
Pubmed	Nephronectin is required to maintain right lung lobar separation during embryonic development.	COL4A1 EGFL6	8.39e-05	6	83	2	36719987
Pubmed	Increases in luteinizing hormone are associated with declines in cognitive performance.	LHB LHCGR	8.39e-05	6	83	2	17376589
Pubmed	C-mip interacts with the p85 subunit of PI3 kinase and exerts a dual effect on ERK signaling via the recruitment of Dip1 and DAP kinase.	CMIP MIB1	8.39e-05	6	83	2	20018188
Pubmed	Comprehensive analysis of reproductive ADAMs: relationship of ADAM4 and ADAM6 with an ADAM complex required for fertilization in mice.	ADAM29 ADAM2	8.39e-05	6	83	2	19129510
Pubmed	Evolution of GABA(A) receptor diversity in the human genome.	GABRB1 GABRB3	8.39e-05	6	83	2	10023064
Pubmed	The GABAA Receptor β Subunit Is Required for Inhibitory Transmission.	GABRB1 GABRB3	8.39e-05	6	83	2	29706582
Pubmed	DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes.	NEUROD6 VCAM1	8.39e-05	6	83	2	14515137
Pubmed	Dependence of uterine cyclooxygenase2 expression on luteinizing hormone signaling.	LHB LHCGR	8.39e-05	6	83	2	15814897
Pubmed	Genetic, personality, and environmental predictors of drug use in adolescents.	GABRB3 DRD2	8.39e-05	6	83	2	19717274
Pubmed	The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships.	SLC10A2 SLC10A6	8.39e-05	6	83	2	16541252
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	FGD1 ECT2 PREX1	1.04e-04	38	83	3	11756498
Pubmed	Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.	SLC10A2 NALCN	1.17e-04	7	83	2	12364586
Pubmed	Integrin α3 is required for late postnatal stability of dendrite arbors, dendritic spines and synapses, and mouse behavior.	ARHGAP35 NEUROD6	1.17e-04	7	83	2	23595732
Pubmed	Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein.	AMER1 FBXW11	1.17e-04	7	83	2	22215675
Pubmed	Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z.	TGM7 TGM5	1.17e-04	7	83	2	11390390
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRB1 GABRB3	1.17e-04	7	83	2	20843900
Pubmed	ADH1B1, ADH1C2, DRD2 (-141C Ins), and 5-HTTLPR are associated with alcoholism in Mexican American men living in Los Angeles.	GABRB3 DRD2	1.17e-04	7	83	2	15318112
Pubmed	Evidence for cross-talk between the LH receptor and LH during implantation in mice.	LHB LHCGR	1.17e-04	7	83	2	23464498
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	SLCO2A1 THOC2 ECT2 GNS GPR45 RYR1	1.40e-04	329	83	6	17474147
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	FGD1 ECT2 PREX1	1.51e-04	43	83	3	12376548
Pubmed	HIV-1 gp120-dependent induction of apoptosis in antigen-specific human T cell clones is characterized by 'tissue' transglutaminase expression and prevented by cyclosporin A.	TGM7 TGM5	1.56e-04	8	83	2	7906657
Pubmed	Human-immunodeficiency-virus transmembrane glycoprotein gp41 is an amino acceptor and donor substrate for transglutaminase in vitro.	TGM7 TGM5	1.56e-04	8	83	2	7688299
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRB1 GABRB3	1.56e-04	8	83	2	11528422
Pubmed	Developmental changes of cell adhesion molecule expression in the fetal mouse liver.	COL4A1 VCAM1	2.00e-04	9	83	2	20687112
Pubmed	Genetic variation in sex hormone genes influences heel ultrasound parameters in middle-aged and elderly men: results from the European Male Aging Study (EMAS).	LHB LHCGR	2.00e-04	9	83	2	18767927
Pubmed	ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.	USP49 USP22	2.00e-04	9	83	2	29669287
Pubmed	Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men.	LHB LHCGR	2.00e-04	9	83	2	20173016
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A2	2.50e-04	10	83	2	23064749
Pubmed	Identification, chromosomal location, and genome organization of mammalian G-protein-coupled receptors.	LHCGR DRD2 EDNRA	2.66e-04	52	83	3	8288218
Pubmed	Non-apical mitoses contribute to cell delamination during mouse gastrulation.	COL4A1 ECT2	3.05e-04	11	83	2	39198421
Pubmed	Single nuclei RNA-seq of mouse placental labyrinth development.	PODXL SLCO2A1	3.66e-04	12	83	2	33141023
Pubmed	USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.	USP49 USP22	3.66e-04	12	83	2	27801882
Pubmed	Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.	AMER1 FBXW11	3.66e-04	12	83	2	22682247
Pubmed	A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory.	GABRB1 GABRB3 DRD2	3.68e-04	58	83	3	11140838
Pubmed	Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).	FGD1 ECT2 PREX1	4.07e-04	60	83	3	12787561
Pubmed	A feedforward circuit shaped by ECT2 and USP7 contributes to breast carcinogenesis.	ECT2 TRIP12	4.31e-04	13	83	2	32929379
Pubmed	A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects.	PODXL ARHGAP35	4.31e-04	13	83	2	26859289
Pubmed	Expression patterns of sulfatase genes in the developing mouse embryo.	SULF1 GNS	4.31e-04	13	83	2	20503373
Pubmed	Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?	GABRB1 DRD2	4.31e-04	13	83	2	17655760
Pubmed	Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse.	GABRB3 LHB	4.31e-04	13	83	2	8601493
Pubmed	The biochemical anatomy of cortical inhibitory synapses.	GABRB1 GABRB3	5.03e-04	14	83	2	22768092
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	UPF2 MIB1 FGD6 PREX1	5.05e-04	153	83	4	10718198
Pubmed	Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome.	GABRB3 LHB LHCGR	5.14e-04	65	83	3	19598235
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	DRD2 SCN1A	5.79e-04	15	83	2	9726281
Pubmed	Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice.	SFTPD LOXL2	5.79e-04	15	83	2	27645581
Pubmed	Embryonic gonadotropin-releasing hormone signaling is necessary for maturation of the male reproductive axis.	LHB LHCGR	6.61e-04	16	83	2	20805495
Pubmed	Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.	AMER1 FBXW11	7.48e-04	17	83	2	17510365
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RAD51B CMIP AMER1 LOXL2 FRYL KIF5C DENND5A ARHGAP35 SPPL2B DNAH14 FBXW11	8.14e-04	1489	83	11	28611215
Pubmed	Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation.	COL4A1 DENND5A	8.40e-04	18	83	2	32496646
Pubmed	Novel cell lines promote the discovery of genes involved in early heart development.	JAK3 VCAM1	8.40e-04	18	83	2	11437454
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRB1 GABRB3	8.40e-04	18	83	2	19078961
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRB1 GABRB3	8.40e-04	18	83	2	18985723
Pubmed	Neurog3-dependent pancreas dysgenesis causes ectopic pancreas in Hes1 mutant mice.	PODXL MIB1	8.40e-04	18	83	2	30093553
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	GABRB1 GABRB3 RAD51B MIB1 ECT2 ADAM22	8.47e-04	462	83	6	31138677
Pubmed	Dissociation of heterotrimeric g proteins in cells.	LHCGR DRD2 P2RY1 EDNRA	9.08e-04	179	83	4	18577758
Pubmed	Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.	PODXL MIB1	9.37e-04	19	83	2	18505817
Pubmed	Lung cancer susceptibility model based on age, family history and genetic variants.	ERCC2 DRD2	9.37e-04	19	83	2	19390575
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AMER1 USP22 FRYL TRIM68 KIF5C ECT2 TRIP12 FGD6	1.05e-03	861	83	8	36931259
Pubmed	Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.	GABRB1 GABRB3	1.15e-03	21	83	2	25708312
Pubmed	The Gsh2 homeodomain gene controls multiple aspects of telencephalic development.	DRD2 NEUROD6	1.15e-03	21	83	2	11060228
Pubmed	The syntenic relationship of proximal mouse chromosome 7 and the myotonic dystrophy gene region on human chromosome 19q.	LHB ERCC2	1.15e-03	21	83	2	2307474
Pubmed	Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development†.	LHCGR VCAM1	1.15e-03	21	83	2	32301970
Pubmed	Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.	MALRD1 SLC10A2	1.15e-03	21	83	2	23747249
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	COL4A1 SULF1 LOXL2	1.16e-03	86	83	3	28327460
Cytoband	15q15.2	TGM7 TGM5	3.81e-04	16	83	2	15q15.2
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	FGD1 ECT2 FGD6 PREX1	4.80e-05	66	55	4	722
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM29 ADAM2 ADAM22	7.40e-05	27	55	3	47
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	FGD1 ZFYVE26 FGD6	1.13e-04	31	55	3	81
GeneFamily	Transglutaminases	TGM7 TGM5	3.23e-04	9	55	2	773
GeneFamily	Sulfatases	SULF1 GNS	1.35e-03	18	55	2	410
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB1 GABRB3	1.50e-03	19	55	2	563
GeneFamily	Solute carriers	SLC10A2 SLCO2A1 SLC10A6 SLC37A2 SLC47A2	6.90e-03	395	55	5	752
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B KIF5C	8.63e-03	46	55	2	622
Coexpression	NABA_ECM_REGULATORS	ADAMTS2 SULF1 LOXL2 ADAM29 TGM7 ADAM2 ADAM22 TGM5	8.21e-07	238	82	8	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTS2 SULF1 LOXL2 ADAM29 TGM7 ADAM2 ADAM22 TGM5	9.31e-07	242	82	8	MM17062
Coexpression	VANHARANTA_UTERINE_FIBROID_UP	COL4A1 SULF1 LOXL2 EDNRA	1.10e-05	44	82	4	M18274
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	GABRB1 GABRB3 KIF21B TLCD3B CMIP NALCN FGD1 ADAM2 KIF5C ADAM22	1.42e-05	584	82	10	M39068
Coexpression	GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_DN	GABRB3 LHB SCN1A DENND5A HHLA1 TRIP12	3.34e-05	194	82	6	M8864
Coexpression	GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN	COL4A1 LHCGR PODXL FRYL GNS ADAM22	3.96e-05	200	82	6	M7469
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_100	GABRB1 NALCN EDNRA EGFL6	1.46e-05	39	81	4	gudmap_developingGonad_P2_epididymis_100_k3
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_200	GABRB1 AMER1 PODXL SULF1 EDNRA EGFL6	3.16e-05	158	81	6	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_200
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500	CMIP ADAM22 EDNRA EGFL6	6.66e-05	57	81	4	gudmap_kidney_P3_CapMes_Crym_k4_500
CoexpressionAtlas	DevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#5_top-relative-expression-ranked_1000	COL4A1 JAK3 LOXL2 TRIP12 EDNRA	8.21e-05	116	81	5	gudmap_developingGonad_e18.5_testes_1000_k5
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#1_top-relative-expression-ranked_200	GABRB1 NALCN EDNRA EGFL6	8.69e-05	61	81	4	gudmap_developingGonad_P2_epididymis_200_k1
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_500	GABRB1 NALCN ADAMTS2 EDNRA EGFL6	1.04e-04	122	81	5	gudmap_developingGonad_P2_epididymis_500_k5
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	GABRB1 AMER1 ADAMTS2 PODXL SULF1 LOXL2 SLC37A2 THOC2 EDNRA RYR1 EGFL6	2.10e-04	795	81	11	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#1_top-relative-expression-ranked_500	GABRB1 NALCN EDNRA EGFL6	2.15e-04	77	81	4	gudmap_developingGonad_e18.5_epididymis_500_k1
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	GABRB1 SULF1 MIB1 THOC2 EDNRA EGFL6	2.22e-04	225	81	6	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	GABRB1 AMER1 SULF1 THOC2 EDNRA EGFL6	2.49e-04	230	81	6	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_100	GABRB1 NALCN EDNRA EGFL6	2.74e-04	82	81	4	gudmap_developingGonad_P2_epididymis_100
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 SLC10A2 PODXL SULF1 SLCO2A1 SLC10A6 VCAM1	8.11e-08	195	83	7	fde8e7b38b3631109b95ef111c5f6e3f9878cfbd
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	COL4A1 P2RY1 ADAMTS2 SULF1 LOXL2 EDNRA	1.33e-06	186	83	6	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_progenitor_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 ADAMTS2 SULF1 LOXL2 VCAM1 EDNRA	1.70e-06	194	83	6	3d25d6ebec8d1b6001f602257cd15b3ba04cf0c1
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A1 ADAMTS2 SULF1 LOXL2 VCAM1 EDNRA	1.70e-06	194	83	6	ff19fb5bc7feae3e774ef4ab720beb9dec219f45
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A1 ADAMTS2 SULF1 LOXL2 NCAPD2 EDNRA	1.76e-06	195	83	6	78cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL4A1 SFTPD PODXL LOXL2 SLC47A2 EDNRA	2.03e-06	200	83	6	ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	COL4A1 SFTPD PODXL LOXL2 SLC47A2 EDNRA	2.03e-06	200	83	6	07d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	JAK3 AMER1 SCN1A ADAM2 ECT2	3.58e-06	124	83	5	a7b7d8b14d1218194da8fcf69b4780b6e9469332
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RAD51B AMER1 USP22 STPG1 VCAM1	1.36e-05	163	83	5	0ab043b68e8739adcedda01165a3758cd0d22728
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS2 PODXL SULF1 NEUROD6 DNAH14	1.57e-05	168	83	5	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	COL4A1 ADAMTS2 LOXL2 KIF5C EDNRA	2.56e-05	186	83	5	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	ERCC2 STXBP2 ZFYVE26 ECT2 GNS	2.62e-05	187	83	5	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	2.76e-05	189	83	5	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL4A1 ADAMTS2 SULF1 EDNRA EGFL6	2.76e-05	189	83	5	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-3\|TCGA-Ovary / Sample_Type by Project: Shred V9	ADAMTS2 SULF1 LOXL2 VCAM1 EDNRA	2.90e-05	191	83	5	80d30d8eedb4c70b58440646325bc04c5700803e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB3 TLCD3B NALCN KIF5C NEUROD6	2.98e-05	192	83	5	fe9297cb65234d9f511bab1a5dbf2679d5a4cd15
ToppCell	facs-Lung-3m-Mesenchymal\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS2 LOXL2 SLC10A6 VCAM1 EDNRA	2.98e-05	192	83	5	8df15085b35b86f39debd933284cb703c5dd63c2
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 PODXL SLCO2A1 SLC10A6 VCAM1	3.13e-05	194	83	5	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 PODXL SLCO2A1 SLC10A6 VCAM1	3.13e-05	194	83	5	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 NALCN ADAMTS2 SULF1 EDNRA	3.21e-05	195	83	5	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	ASK440-Endothelial-Endothelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL4A1 PODXL SULF1 SLCO2A1 VCAM1	3.21e-05	195	83	5	304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCell	Endothelial-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 PODXL SLCO2A1 SLC10A6 VCAM1	3.21e-05	195	83	5	c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCell	IPF-Endothelial-VE_Peribronchial\|IPF / Disease state, Lineage and Cell class	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	3.21e-05	195	83	5	2c3ad3cb79f11119ac69c413a938d21199145040
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 NALCN ADAMTS2 SULF1 EDNRA	3.21e-05	195	83	5	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 PODXL SLCO2A1 PREX1 VCAM1	3.29e-05	196	83	5	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS2 SULF1 LOXL2 VCAM1 EDNRA	3.29e-05	196	83	5	d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 NALCN ADAMTS2 SULF1 EDNRA	3.29e-05	196	83	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 NALCN ADAMTS2 SULF1 EDNRA	3.29e-05	196	83	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 DPY19L2 ADAMTS2 SULF1 EDNRA	3.37e-05	197	83	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	COL4A1 LOXL2 ECT2 FGD6 CYRIB	3.37e-05	197	83	5	1bb8f9535a9ab6c7a444bcbe346fcc0a13b09bdf
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Endothelial-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	3.37e-05	197	83	5	f969685dee212f33a6f09e54c0cd1fd24ffef546
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	3.37e-05	197	83	5	1a137af40697137bb9d2b5caf2b1ffda55f04461
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 ADAMTS2 LOXL2 EDNRA EGFL6	3.37e-05	197	83	5	452be45f4aac8459dd860493171f5f715368d663
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	USP49 P2RY1 DENND5A FGD6 RYR1	3.37e-05	197	83	5	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Endothelial-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	3.37e-05	197	83	5	96d63a8d00583e2aa0a38412e2ae27e23f399493
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	USP49 P2RY1 DENND5A FGD6 RYR1	3.37e-05	197	83	5	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CMIP ADAMTS2 SULF1 LOXL2 VCAM1	3.45e-05	198	83	5	09be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell	ASK452-Endothelial-Endothelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	3.45e-05	198	83	5	e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 ADAMTS2 SULF1 LOXL2 EDNRA	3.45e-05	198	83	5	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 CMIP ADAMTS2 LOXL2 VCAM1	3.45e-05	198	83	5	7582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GABRB1 ADAMTS2 LOXL2 VCAM1 EDNRA	3.53e-05	199	83	5	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GABRB1 ADAMTS2 LOXL2 VCAM1 EDNRA	3.53e-05	199	83	5	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	Sepsis-URO\|Sepsis / Disease, condition lineage and cell class	JAK3 STXBP2 P2RY1 ADAMTS2 GNS	3.53e-05	199	83	5	8e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL4A1 PODXL LOXL2 SLCO2A1 VCAM1	3.53e-05	199	83	5	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GABRB1 ADAMTS2 LOXL2 VCAM1 EDNRA	3.53e-05	199	83	5	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL4A1 SULF1 LOXL2 EDNRA EGFL6	3.62e-05	200	83	5	fee22a6a6c7b93af204b5b56f2c34f1411500e18
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 JAK3 CMIP SLCO2A1 VCAM1	3.62e-05	200	83	5	50b8788494b744e0f0ec8c4d67a1c90ae09dca65
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial-Proteoglycan-expressing_cell\|3m / Sample Type, Dataset, Time_group, and Cell type.	COL4A1 SULF1 LOXL2 EDNRA EGFL6	3.62e-05	200	83	5	94ef227b2162ba77af33b8cc8aaa4a7e3bdf79a7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	GABRB3 KIF21B TLCD3B CMIP KIF5C	3.62e-05	200	83	5	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	390C-Endothelial_cells-Endothelial-A_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 JAK3 CMIP SLCO2A1 VCAM1	3.62e-05	200	83	5	f5f24273bee3259a4a3be99ba53b88defa1286c0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal\|6m / Sample Type, Dataset, Time_group, and Cell type.	GABRB3 KIF21B TLCD3B KIF5C NEUROD6	3.62e-05	200	83	5	cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	GABRB3 KIF21B TLCD3B KIF5C NEUROD6	3.62e-05	200	83	5	6f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial\|3m / Sample Type, Dataset, Time_group, and Cell type.	COL4A1 SULF1 LOXL2 EDNRA EGFL6	3.62e-05	200	83	5	429028c3112d279b26abf3296e01b1884b4b7fcb
ToppCell	(5)_Fibroblast-B_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL4A1 ADAMTS2 SULF1 LOXL2 EDNRA	3.62e-05	200	83	5	9bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCell	mLN-Dendritic_cell-cDC1\|Dendritic_cell / Region, Cell class and subclass	CMIP SLCO2A1 SLC37A2 VCAM1	3.69e-05	100	83	4	c560326f6ae5338aecdf11ef8adf04bc8769745c
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	P2RY1 SLC10A6 SLC37A2 ARHGAP35	8.01e-05	122	83	4	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAQR9 STPG1 SCN1A ADAM2	1.33e-04	139	83	4	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	P03-Hematopoietic-Erythroid\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAQR9 TLCD3B MYO15A RYR1	1.52e-04	144	83	4	2ee6a834860eac7ed004f366ab4fc38c4b80c905
ToppCell	P03-Hematopoietic-Erythroid-enucleate_erythrocyte\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAQR9 TLCD3B MYO15A RYR1	1.52e-04	144	83	4	9fa63904389f4d7163db22ea85ab721d8f6e8d99
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STXBP2 DPY19L1 LOXL2 NEUROD6	1.73e-04	149	83	4	558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLC10A2 DDX49 LOXL2 SCN1A	1.78e-04	150	83	4	6f7087a051a2f05c5611ff65a945c01736d5ec2b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-NP\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STXBP2 LOXL2 NEUROD6 FGD6	1.87e-04	152	83	4	b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 LHCGR PODXL TRIM68	1.87e-04	152	83	4	acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A1 LHCGR PODXL TRIM68	1.87e-04	152	83	4	9d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|390C / Donor, Lineage, Cell class and subclass (all cells)	USP49 UPF2 FGD6 PREX1	2.02e-04	155	83	4	98d8432739965dd1ab77c899cb6321f7f05eaa46
ToppCell	Int-URO-Lymphocyte-T_NK-CD8_TCM\|Int-URO / Disease, Lineage and Cell Type	TLCD3B OXNAD1 ADAM22 RFPL3S	2.17e-04	158	83	4	edcc5a26d4571b179f3ae538fed23b661e4677dd
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF21B P2RY1 THOC2 ADAM22	2.39e-04	162	83	4	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AP4E1 STPG1 LOXL2 ADAM22	2.44e-04	163	83	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 LHB ADAM22 EDNRA	2.56e-04	165	83	4	3d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTS2 SLC37A2 PREX1 TMEM236	2.62e-04	166	83	4	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	WDR19 ERCC2 CMTR2 FBXW11	2.68e-04	167	83	4	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	COL4A1 JAK3 ADAMTS2 EGFL6	2.74e-04	168	83	4	aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell	facs-Aorta-Heart-24m-Endothelial-endocardial_endothelial_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B SLCO2A1 NEUROD6 VCAM1	2.74e-04	168	83	4	edbab94f14e16a1a76546a18fe777a183080d1de
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB3 TLCD3B NALCN KIF5C	2.80e-04	169	83	4	606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 KIF21B LRRC37A2 TMEM236	2.80e-04	169	83	4	0589f39d8e9468e42d25d30ff70bb7cb8b921628
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB3 TLCD3B NALCN KIF5C	2.80e-04	169	83	4	052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 DPY19L2 EDNRA EGFL6	2.87e-04	170	83	4	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	AT1-AT2_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	DPY19L1 PODXL SLCO2A1 VCAM1	2.93e-04	171	83	4	0b9912f07393aca889db72b40da08e0bc9bc1e8c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 SULF1 EDNRA EGFL6	2.93e-04	171	83	4	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 DPY19L2 EDNRA EGFL6	3.00e-04	172	83	4	107417cfab7775bc1f80807115047abfb50b7a7e
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB1 P2RY1 SLCO2A1 FGD6	3.00e-04	172	83	4	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 AMER1 ADAM22 EDNRA	3.06e-04	173	83	4	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A1 AMER1 ADAM22 EDNRA	3.06e-04	173	83	4	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	CMIP P2RY1 SLC10A6 SLC37A2	3.20e-04	175	83	4	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB\|TCGA-Thymus / Sample_Type by Project: Shred V9	NALCN EDNRA RYR1 EGFL6	3.20e-04	175	83	4	50f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell	facs-Skin-nan-24m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB3 MYO15A TGM5 EGFL6	3.20e-04	175	83	4	f1166b567bca80dac3abe90c3dc544c831006640
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DRD2 DPY19L2 ADAM2 EDNRA	3.34e-04	177	83	4	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR19 SFTPD PREX1 ADAM22	3.34e-04	177	83	4	14fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFTPD NCAPD2 ECT2 EGFL6	3.34e-04	177	83	4	a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL4A1 STPG1 PODXL SLCO2A1	3.34e-04	177	83	4	0e74980a7686c31fcf1476b8f19a3392541df240
ToppCell	LPS-antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAD51B JAK3 STXBP2 SFTPD	3.41e-04	178	83	4	289d1425c4e57fabcca994b27f9af1c0ce5d5bec
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A1 DPY19L1 DENND5A VCAM1	3.41e-04	178	83	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	CMIP SULF1 SLCO2A1 VCAM1	3.48e-04	179	83	4	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	Fetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A1 PODXL SLCO2A1 PREX1	3.56e-04	180	83	4	d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAD51B JAK3 VCAM1 EDNRA	3.56e-04	180	83	4	f103e161e966c257eac97e1b30a461c4ed9cafc2
ToppCell	Endothelial-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 PODXL SLCO2A1 VCAM1	3.56e-04	180	83	4	4c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell	COPD-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	COL4A1 PODXL LOXL2 SLCO2A1	3.63e-04	181	83	4	61608123959483ff60f07d8467996853c4371b6a
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GABRB1 DPY19L2 NALCN ADAMTS2	3.63e-04	181	83	4	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	Severe-Lymphoid-T-innate_T\|Severe / Condition, Lineage, Cell class and cell subclass	OXNAD1 ADAM29 KIF5C VCAM1	3.63e-04	181	83	4	50ab8562552339d97e4f19aa6ae49fd797da492e
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 STXBP2 FGD1 EGFL6	3.63e-04	181	83	4	35c470988a93381eefa300831aabb813fa1b90bd
Drug	thieno[2,3-d]pyrimidine	LHCGR VCAM1 EDNRA	9.27e-07	6	83	3	CID012225304
Drug	mono-(2-ethylhexyl)phthalate	LHB LHCGR KIF21B NALCN DPY19L1 LOXL2 SCN1A KIF5C MYO15A ADAM22 DNAH14 RYR1	4.57e-06	658	83	12	ctd:C016599
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; MCF7; HT_HG-U133A	RAD51B AP4E1 DRD2 FGD1 ARHGAP35 CYRIB EDNRA	7.27e-06	195	83	7	2266_DN
Drug	Nitrazepam	GABRB1 GABRB3 SCN1A	7.55e-06	11	83	3	DB01595
Drug	Gabrene	GABRB1 GABRB3 DRD2 SLCO2A1	1.36e-05	40	83	4	CID005361323
Drug	AC1O6F2N	LHB LHCGR EDNRA	3.06e-05	17	83	3	CID006473746
Drug	17 alpha-hydroxy-20 beta-dihydroprogesterone	LHB LHCGR DRD2	6.84e-05	22	83	3	CID000107701
Drug	dehydroepiandrosterone sulfate	GABRB1 GABRB3 LHCGR SLC10A2 P2RY1 SLCO2A1 SLC10A6	6.90e-05	277	83	7	CID000005244
Drug	Tolazamide [1156-19-0]; Up 200; 12.8uM; MCF7; HT_HG-U133A	ERCC2 ARHGAP35 HHLA1 GNS ADAM22 CYRIB	7.54e-05	193	83	6	2842_UP
Drug	Glycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A	CNPPD1 LOXL2 KIF5C ARHGAP35 FGD6 FBXW11	7.75e-05	194	83	6	5316_DN
Drug	tunicamycin B2	LHB LHCGR	7.84e-05	4	83	2	CID006438721
Drug	Fillalbin [4540-25-4]; Down 200; 13.8uM; PC3; HT_HG-U133A	P2RY1 LOXL2 KIF5C ARHGAP35 MYO15A FBXW11	7.98e-05	195	83	6	4092_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A	ERCC2 LOXL2 ADAM2 ARHGAP35 GNS ADAM22	7.98e-05	195	83	6	3862_UP
Drug	Adamantamine fumarate [80789-67-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A	COL4A1 RAD51B JAK3 DRD2 FGD1 ADAM2	8.21e-05	196	83	6	4806_UP
Drug	Metoclopramide monohydrochloride [7232-21-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	KIF21B ERCC2 P2RY1 FGD1 ADAM22 RYR1	8.21e-05	196	83	6	4750_UP
Drug	Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A	KIF21B AP4E1 SULF1 SLCO2A1 SPPL2B ADAM22	8.44e-05	197	83	6	6250_UP
Drug	GSK-3 Inhibitor IX; Down 200; 0.5uM; MCF7; HT_HG-U133A	RAD51B JAK3 SULF1 NCAPD2 FRYL FBXW11	8.44e-05	197	83	6	7101_DN
Drug	Enoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A	COL4A1 SLCO2A1 SPPL2B ADAM22 EDNRA RYR1	8.44e-05	197	83	6	5616_UP
Drug	Harmalol hydrochloride dihydrate [6028-07-5]; Up 200; 14.6uM; PC3; HT_HG-U133A	AP4E1 SLC10A2 SULF1 ARHGAP35 ADAM22 CYRIB	8.44e-05	197	83	6	5076_UP
Drug	Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; HL60; HT_HG-U133A	DRD2 SLCO2A1 KIF5C ARHGAP35 ADAM22 VCAM1	8.44e-05	197	83	6	2718_UP
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; HL60; HT_HG-U133A	RAD51B DRD2 SLCO2A1 KIF5C ARHGAP35 EDNRA	8.68e-05	198	83	6	2732_UP
Drug	Cefadroxil [50370-12-2]; Down 200; 11uM; MCF7; HT_HG-U133A	RAD51B AP4E1 ERCC2 SULF1 SPPL2B EDNRA	8.68e-05	198	83	6	3259_DN
Drug	Novobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; MCF7; HT_HG-U133A	JAK3 SLCO2A1 PRAMEF12 MYO15A ADAM22 RYR1	8.68e-05	198	83	6	4392_UP
Drug	Oxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; HL60; HT_HG-U133A	DRD2 SLCO2A1 PRAMEF12 KIF5C EDNRA RYR1	8.68e-05	198	83	6	6145_UP
Drug	Cinoxacin [28657-80-9]; Up 200; 15.2uM; HL60; HT_HG-U133A	RAD51B DRD2 SLCO2A1 FGD1 ADAM22 EDNRA	9.17e-05	200	83	6	2722_UP
Drug	alpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A	SULF1 LOXL2 SLCO2A1 ARHGAP35 HHLA1 RYR1	9.17e-05	200	83	6	3795_UP
Disease	Leydig Cell Tumor	LHB LHCGR	2.23e-05	3	81	2	C0023601
Disease	Malignant neoplasm of breast	RAD51B LHCGR LRRC37A STPG1 ACADM LOXL2 LRRC37A2 SLC10A6 ZFYVE26 ECT2 GPR45 EDNRA	3.55e-05	1074	81	12	C0006142
Disease	Cerebral Small Vessel Diseases	COL4A1 SCN1A	7.40e-05	5	81	2	C2733158
Disease	Lennox-Gastaut syndrome	GABRB3 SCN1A	1.11e-04	6	81	2	C0238111
Disease	Hyperprolactinemia	LHB DRD2	1.11e-04	6	81	2	C0020514
Disease	Testotoxicosis	LHB LHCGR	2.06e-04	8	81	2	C1504412
Disease	xanthine measurement	RAD51B ADAM22	5.69e-04	13	81	2	EFO_0010548
Disease	Tachycardia	LHB DRD2	1.11e-03	18	81	2	C0039231
Disease	metabolically healthy obesity	SLC10A2 P2RY1	1.11e-03	18	81	2	EFO_0009382
Disease	Tachyarrhythmia	LHB DRD2	1.11e-03	18	81	2	C0080203
Disease	pulmonary hypertension (biomarker_via_orthology)	COL4A1 VCAM1 RYR1	1.41e-03	80	81	3	DOID:6432 (biomarker_via_orthology)
Disease	post-traumatic stress disorder symptom measurement	RAD51B SULF1 LRRC37A2	1.51e-03	82	81	3	EFO_0008535
Disease	Attention Deficit Disorder	DRD2 FGD1	1.66e-03	22	81	2	C0041671
Disease	Minimal Brain Dysfunction	DRD2 FGD1	1.66e-03	22	81	2	C1321905
Disease	lung disease (is_implicated_in)	SFTPD EDNRA	1.66e-03	22	81	2	DOID:850 (is_implicated_in)
Disease	Autism Spectrum Disorders	GABRB3 SCN1A TRIP12	1.67e-03	85	81	3	C1510586
Disease	Etat Marbre	DRD2 SCN1A	1.81e-03	23	81	2	C0266487
Disease	Hypertensive disease	LHB DRD2 VCAM1 EDNRA	1.88e-03	190	81	4	C0020538
Disease	Attention deficit hyperactivity disorder	DRD2 FGD1	1.98e-03	24	81	2	C1263846
Disease	migraine disorder, diastolic blood pressure	COL4A1 STXBP2	2.14e-03	25	81	2	EFO_0006336, MONDO_0005277
Disease	Neurodevelopmental Disorders	GABRB3 SCN1A TRIP12	2.16e-03	93	81	3	C1535926
Disease	Bradycardia	LHB DRD2	2.32e-03	26	81	2	C0428977
Disease	migraine disorder, pulse pressure measurement	COL4A1 STXBP2	2.32e-03	26	81	2	EFO_0005763, MONDO_0005277
Disease	Nephrotic Syndrome	COL4A1 PODXL	2.50e-03	27	81	2	C0027726

Protein segments in the cluster

Peptide	Gene	Start	Entry
MCTPHRSCAIVTFMN	ADAM29	306	Q9UKF5
LMPDATCVNSRTCAM	EGFL6	126	Q8IUX8
CLFMSKERMCRPSFE	ADAM2	436	Q99965
MMCLEHRCLPVASFN	ADAM22	661	Q9P0K1
CLMVSPACSTMSIEL	CMIP	431	Q8IY22
DVMILPVLSCFTRFM	CMTR2	641	Q8IYT2
QATCCIPPMTMSISL	AMER1	991	Q5JTC6
MPLVCTAIFYTLMTC	EDNRA	266	P25101
LGRMTEEPLMCAYCV	ACADM	146	P11310
MMCTAFRTFDPCKQL	ADAMTS2	501	O95450
CMALTVVSQIFPCEM	AP4E1	151	Q9UPM8
SRCAVCEAPAMVMAV	COL4A1	1546	P02462
ELLCMVSRACAPKMQ	RAD51B	51	O15315
FSCRPLYCTSMMNLV	ECT2	166	Q9H8V3
KSCSPSAEFLRMMGC	JAK3	1026	P52333
IYSMCTTVAMFCVPL	P2RY1	216	P47900
DRFSMPLIITIVCMA	PODXL	456	O00592
MAILIFTDFTCMAPI	LHCGR	571	P22888
MSSAQCPALVCVMSR	LRRC37A2	1	A6NM11
MSSAQCPALVCVMSR	LRRC37A	1	A6NMS7
MCVSVLSRLCKVMPN	MYO15A	1861	Q9UKN7
TTICAGYCPTMMRVL	LHB	51	P01229
MERPLCSHLCSCLAM	LOXL2	1	Q9Y4K0
ESMCALSCLQSMPSV	FBXW11	31	Q9UKB1
SLEVMMLCSECPTVF	FRYL	2746	O94915
TIMIACVSPSDRDFM	KIF21B	341	O75037
TPHMCVMASLICSRQ	DPY19L1	476	Q2PZI1
FTMTLARVCLCPMII	ERCC2	481	P18074
GLLSFPVMITMVCCA	GABRB1	11	P18505
TTTAACMMDLRRYPL	GABRB1	156	P18505
TTTAACMMDLRRYPL	GABRB3	156	P28472
MAFCSITAPKMICDI	OR4F15	71	Q8NGB8
TDVTLCTTMVPNMLC	OR52N2	71	Q8NGI0
TPHMCVMASLICSRQ	DPY19L2	561	Q6NUT2
IMLSLCCMPFTAVTL	GPR45	81	Q9Y5Y3
ALRTFVFVMPLSMAC	PAQR9	241	Q6ZVX9
TMCPVCLDRLKNMIF	MIB1	961	Q86YT6
FLLSACDSLCIPMVM	MEI1	546	Q5TIA1
MACAAVMIPGLLRCS	OXNAD1	1	Q96HP4
DRMLAFPMNETFCCL	MALRD1	6	Q5VYJ5
MEAFTRRCCETLTTM	PRAMEF12	41	O95522
RATTCCVMLILAAPM	SLC37A2	361	Q8TED4
SREACISPCAMMLAL	CNPPD1	86	Q9BV87
CICLITPMSFMKACR	DENND5A	206	Q6IQ26
TVSRCAMVYMDPVDL	DNAH14	1626	Q0VDD8
RLMMLQSCSGPTCRT	GNS	506	P15586
CQILCMMLRKFSFPT	DDX49	261	Q9Y6V7
TDCLSTMASVCRVML	CYRIB	221	Q9NUQ9
TMASVCRVMLETPEY	CYRIB	226	Q9NUQ9
CAISIDRYTAVAMPM	DRD2	126	P14416
CLMSLCRYIRPSMLQ	RYR1	2606	P21817
PCMSDVAEDLCSMLR	UPF2	631	Q9HAU5
TCSTLLALGMMPLCL	SLC10A2	131	Q12908
CLCMSQRSPRTEDMR	HHLA1	476	C9JL84
VMLTCSVMGCESPSF	VCAM1	331	P19320
FFSLAVPSMLMICVE	SLC47A2	291	Q86VL8
MADPAECSIKVMCRF	KIF5C	1	O60282
TPIREKEVTMCMRCQ	FGD1	726	P98174
CRRLMALSSAIVTMP	PREX1	901	Q8TCU6
IMLNTESTCPMCSER	WDR19	1306	Q8NEZ3
ICMDSYSMPLTSIQC	RNF220	516	Q5VTB9
DLRIVMCLMCGDPFS	ARHGAP35	781	Q9NRY4
CTILTNCVFMTMSNP	SCN1A	136	P35498
CCPLERCSSVMLLGM	NCAPD2	766	Q15021
TISMILCVPLFFMGC	SLCO2A1	406	Q92959
CEMQSPSSCLVCEMS	USP22	211	Q9UPT9
CPICMTFLREPMSID	TRIM68	16	Q6AZZ1
LLESYMSMCEPQTLC	THOC2	231	Q8NI27
LLPSLSLMDCNACMS	THOC2	491	Q8NI27
YSHRTMPSACTLVMC	SFTPD	26	P35247
TCMFPSMCARLDTII	STPG1	91	Q5TH74
CVMSPLRTLLRSSEM	RFPL3S	16	P0C7P2
LIMDHPSMRILSSCC	STXBP2	31	Q15833
PSMRILSSCCKMSDI	STXBP2	36	Q15833
VTPVMTCVFVVMCCS	SPPL2B	221	Q8TCT7
PDTRATMCMICTSEF	FGD6	1221	Q6ZV73
VLTMEPYCCRDMLSS	USP49	576	Q70CQ1
TCSTVAALGMMPLCI	SLC10A6	131	Q3KNW5
FAAVMCTVMRCLGIP	TGM5	281	O43548
CMLMAEVSTPFVCLG	TLCD3B	161	Q71RH2
MCTVMRCLGVPTRVV	TGM7	286	Q96PF1
VVRMFSLMCSNCPTL	TRIP12	671	Q14669
SLMCSNCPTLAVQLM	TRIP12	676	Q14669
FVTTPMCCPSRSSML	SULF1	81	Q8IWU6
SCCVEDPSTVMNMIL	ZFYVE26	1541	Q68DK2
MMCVVLTTLPCLTFS	TMEM236	91	Q5W0B7
TICSCISMMFESPFR	NALCN	896	Q8IZF0
VMPESQMCRKFSREC	NEUROD6	11	Q96NK8