Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintegrin binding

VWF LAMB2 ITGB2 EGFR TNN TNR LTBP4

3.23e-051751027GO:0005178
GeneOntologyMolecularFunctionextracellular matrix structural constituent

VWF LAMB2 TECTA SSPOP HMCN2 LTBP4 MUC5AC

5.10e-051881027GO:0005201
GeneOntologyMolecularFunction5-methylcytosine dioxygenase activity

TET2 TET1

7.73e-0531022GO:0070579
GeneOntologyMolecularFunctionRNA uridylyltransferase activity

TUT4 TUT1

7.73e-0531022GO:0050265
GeneOntologyMolecularFunctionglial cell-derived neurotrophic factor receptor activity

GFRA4 GFRA2

2.56e-0451022GO:0016167
GeneOntologyMolecularFunctionopsonin binding

ITGB2 C4A C4B

2.74e-04251023GO:0001846
GeneOntologyMolecularFunctionmethyl-CpG binding

CXXC5 TET1 CXXC4

5.24e-04311023GO:0008327
GeneOntologyMolecularFunctionuridylyltransferase activity

TUT4 TUT1

5.34e-0471022GO:0070569
GeneOntologyMolecularFunctioncomplement binding

ITGB2 C4A C4B

5.76e-04321023GO:0001848
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C4A C4B

1.13e-03101022GO:0001849
GeneOntologyCellularComponentextracellular matrix

VWF ZAN LAMB2 MUC5B TECTA SSPOP FCGBP HMCN2 TNN TNR LTBP4 MUC5AC CDH13

1.64e-0565610113GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

VWF ZAN LAMB2 MUC5B TECTA SSPOP FCGBP HMCN2 TNN TNR LTBP4 MUC5AC CDH13

1.70e-0565810113GO:0030312
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB2 TNN TNR

7.09e-05171013GO:0098637
GeneOntologyCellularComponentcell surface

IL12RB1 VWF TRGC2 GFRA4 ITGB2 GFRA2 TNFRSF4 BMPR1A EGFR TNN GJD3 RSPO2 CORIN LPAR2 TNR CDH13

8.18e-05111110116GO:0009986
GeneOntologyCellularComponenttenascin complex

TNN TNR

1.38e-0441012GO:0090733
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMB2 ITGB2 TNN TNR

1.91e-04591014GO:0098636
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

6.35e-0481012GO:0106139
GeneOntologyCellularComponentplasma membrane raft

CD320 ITGB2 BMPR1A CDH13 VDR

7.40e-041471015GO:0044853
GeneOntologyCellularComponentother organism part

C4A C4B

8.14e-0491012GO:0044217
GeneOntologyCellularComponentexternal side of plasma membrane

IL12RB1 VWF TRGC2 GFRA4 ITGB2 GFRA2 TNFRSF4 BMPR1A CDH13

9.24e-045191019GO:0009897
GeneOntologyCellularComponentside of membrane

IL12RB1 VWF TRGC2 GAS1 TECTA GFRA4 ITGB2 GFRA2 TNFRSF4 ESYT3 BMPR1A CDH13

1.04e-0387510112GO:0098552
GeneOntologyCellularComponentplasma membrane protein complex

IL12RB1 CATSPERD TRGC2 SSPOP ITGB2 LRRC55 BMPR1A EGFR GJD3 C8B CDH13

1.44e-0378510111GO:0098797
GeneOntologyCellularComponentmembrane raft

CD320 ITGB2 BMPR1A EGFR TNR CDH13 VDR

1.88e-033621017GO:0045121
GeneOntologyCellularComponentmembrane microdomain

CD320 ITGB2 BMPR1A EGFR TNR CDH13 VDR

1.94e-033641017GO:0098857
GeneOntologyCellularComponentcaveola

CD320 BMPR1A CDH13 VDR

2.07e-031111014GO:0005901
DomainVWC

VWF ZAN KCP MUC5B TECTA SSPOP NELL2 FCGBP PXDNL CHRDL1 MUC5AC

4.98e-17389811SM00214
DomainVWF_dom

VWF ZAN KCP MUC5B TECTA SSPOP NELL2 FCGBP PXDNL CHRDL1 MUC5AC

1.74e-16429811IPR001007
DomainVWC_out

VWF ZAN KCP MUC5B TECTA SSPOP NELL2 FCGBP MUC5AC

1.83e-1619989SM00215
DomainUnchr_dom_Cys-rich

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

5.41e-1613988IPR014853
DomainC8

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

5.41e-1613988SM00832
DomainTIL_dom

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

1.26e-1514988IPR002919
DomainVWFC_2

VWF ZAN KCP MUC5B TECTA SSPOP NELL2 PXDNL CHRDL1 MUC5AC

4.13e-15389810PS50184
DomainVWD

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

5.34e-1516988SM00216
DomainVWF_type-D

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

5.34e-1516988IPR001846
DomainVWFD

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

5.34e-1516988PS51233
DomainVWD

VWF ZAN KCP MUC5B TECTA SSPOP FCGBP MUC5AC

5.34e-1516988PF00094
DomainTIL

VWF ZAN MUC5B TECTA SSPOP FCGBP MUC5AC

6.83e-1412987PF01826
DomainC8

VWF ZAN MUC5B TECTA SSPOP FCGBP MUC5AC

6.83e-1412987PF08742
DomainVWFC_1

VWF ZAN KCP MUC5B SSPOP NELL2 PXDNL CHRDL1 MUC5AC

1.73e-1336989PS01208
DomainVWC

VWF KCP MUC5B NELL2 PXDNL CHRDL1 MUC5AC

9.53e-1128987PF00093
DomainEGF-like_dom

ZAN LAMB2 TECTA NELL2 CELSR1 FCGBP HMCN2 TNN C8B TNR LTBP4

7.65e-082499811IPR000742
DomainEGF_1

ZAN LAMB2 SSPOP ITGB2 NELL2 CELSR1 HMCN2 TNN C8B TNR LTBP4

9.74e-082559811PS00022
DomainTILa

ZAN TECTA FCGBP

1.40e-073983PF12714
DomainTILa_dom

ZAN TECTA FCGBP

1.40e-073983IPR025615
DomainEGF_2

ZAN LAMB2 SSPOP ITGB2 NELL2 CELSR1 HMCN2 TNN C8B TNR LTBP4

1.44e-072659811PS01186
DomainEGF-like_CS

ZAN LAMB2 ITGB2 NELL2 CELSR1 HMCN2 TNN C8B TNR LTBP4

1.14e-062619810IPR013032
DomainDUF4704

NBEAL1 NBEA LRBA

1.39e-065983IPR031570
DomainDUF4704

NBEAL1 NBEA LRBA

1.39e-065983PF15787
DomainGrowth_fac_rcpt_

LAMB2 NELL2 CELSR1 HMCN2 EGFR TNN RSPO2 LTBP4

1.65e-06156988IPR009030
DomainCTCK_1

VWF MUC5B SSPOP MUC5AC

2.06e-0618984PS01185
DomainPH_BEACH

NBEAL1 NBEA LRBA

2.77e-066983PF14844
DomainGDNF

GAS1 GFRA4 GFRA2

2.77e-066983SM00907
DomainGDNF

GAS1 GFRA4 GFRA2

2.77e-066983PF02351
DomainGDNF/GAS1

GAS1 GFRA4 GFRA2

2.77e-066983IPR016017
DomainEGF_3

ZAN SSPOP NELL2 CELSR1 HMCN2 TNN C8B TNR LTBP4

4.04e-06235989PS50026
DomainEGF

ZAN LAMB2 TECTA NELL2 CELSR1 FCGBP TNN TNR LTBP4

4.04e-06235989SM00181
DomainPH-BEACH_dom

NBEAL1 NBEA LRBA

7.70e-068983IPR023362
Domain-

NBEAL1 NBEA LRBA

7.70e-0689832.30.29.40
DomainPH_BEACH

NBEAL1 NBEA LRBA

7.70e-068983PS51783
DomainCys_knot_C

VWF MUC5B SSPOP MUC5AC

8.28e-0625984IPR006207
DomainCTCK_2

VWF MUC5B SSPOP MUC5AC

8.28e-0625984PS01225
DomainBEACH_dom

NBEAL1 NBEA LRBA

1.15e-059983IPR000409
DomainBEACH

NBEAL1 NBEA LRBA

1.15e-059983PS50197
DomainBeach

NBEAL1 NBEA LRBA

1.15e-059983PF02138
Domain-

NBEAL1 NBEA LRBA

1.15e-0599831.10.1540.10
DomainBeach

NBEAL1 NBEA LRBA

1.15e-059983SM01026
DomainZnf_CXXC

CXXC5 TET1 CXXC4

2.24e-0511983IPR002857
DomainZF_CXXC

CXXC5 TET1 CXXC4

2.24e-0511983PS51058
Domainzf-CXXC

CXXC5 TET1 CXXC4

2.24e-0511983PF02008
DomainTet_JBP

TET2 TET1

2.73e-052982PF12851
Domain2OGFeDO_noxygenase_dom

TET2 TET1

2.73e-052982IPR024779
DomainDUF1088

NBEA LRBA

2.73e-052982IPR010508
DomainDUF1088

NBEA LRBA

2.73e-052982PF06469
DomainTet_JBP

TET2 TET1

2.73e-052982SM01333
DomainLDLR_class-A_CS

CD320 SSPOP CORIN C8B

5.63e-0540984IPR023415
DomainLdl_recept_a

CD320 SSPOP CORIN C8B

9.00e-0545984PF00057
DomainLDLRA_1

CD320 SSPOP CORIN C8B

1.16e-0448984PS01209
DomainLDLRA_2

CD320 SSPOP CORIN C8B

1.26e-0449984PS50068
DomainLDrepeatLR_classA_rpt

CD320 SSPOP CORIN C8B

1.26e-0449984IPR002172
DomainLDLa

CD320 SSPOP CORIN C8B

1.26e-0449984SM00192
Domain-

NBEAL1 NBEA NELL2 CELSR1 LRBA

1.43e-04959852.60.120.200
DomainCT

VWF MUC5B MUC5AC

2.01e-0422983SM00041
DomainAnaphylatoxin_comp_syst

C4A C4B

2.70e-045982IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

2.70e-045982IPR001840
DomainGDNF_rcpt

GFRA4 GFRA2

2.70e-045982IPR003438
DomainEGF_extracell

ITGB2 NELL2 TNN TNR

2.77e-0460984IPR013111
DomainEGF_2

ITGB2 NELL2 TNN TNR

2.77e-0460984PF07974
DomainWxxW_domain

MUC5B MUC5AC

4.03e-046982IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

4.03e-046982PF13330
DomainANATO

C4A C4B

5.63e-047982SM00104
DomainANATO

C4A C4B

5.63e-047982PF01821
DomainPAP_assoc

TUT4 TUT1

5.63e-047982PF03828
DomainANAPHYLATOXIN_2

C4A C4B

5.63e-047982PS01178
DomainANAPHYLATOXIN_1

C4A C4B

5.63e-047982PS01177
DomainPAP_assoc

TUT4 TUT1

5.63e-047982IPR002058
DomainAnaphylatoxin/fibulin

C4A C4B

5.63e-047982IPR000020
DomainThiol-ester_cl

C4A C4B

7.48e-048982PF10569
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

7.48e-048982IPR019565
DomainMacrogloblnA2_CS

C4A C4B

7.48e-048982IPR019742
DomainZnf_FYVE

RNF34 SYTL5 FGD3

1.03e-0338983IPR000306
DomainConA-like_dom

ZAN NBEAL1 NBEA NELL2 CELSR1 LRBA

1.04e-03219986IPR013320
DomainZnf_FYVE_PHD

RNF34 BAZ2A SYTL5 MLLT6 FGD3

1.06e-03147985IPR011011
DomainA2M_N

C4A C4B

1.19e-0310982PF01835
DomainA2M_N

C4A C4B

1.19e-0310982IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

1.19e-0310982IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

1.19e-0310982PS00477
DomainA2M

C4A C4B

1.19e-0310982PF00207
DomainA2M_N_2

C4A C4B

1.19e-0310982IPR011625
DomainA2M_comp

C4A C4B

1.19e-0310982IPR011626
DomainA2M_N_2

C4A C4B

1.19e-0310982PF07703
DomainA2M_recep

C4A C4B

1.19e-0310982PF07677
DomainA2M_comp

C4A C4B

1.19e-0310982PF07678
DomainMacroglobln_a2

C4A C4B

1.19e-0310982IPR001599
DomainZF_FYVE

RNF34 SYTL5 FGD3

1.20e-0340983PS50178
Domain-

CD320 SSPOP CORIN

1.81e-03469834.10.400.10
DomainASX_HYDROXYL

NELL2 CELSR1 HMCN2 LTBP4

1.90e-03100984PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL2 CELSR1 HMCN2 LTBP4

2.35e-03106984IPR000152
DomainGlyco_hormone_CN

MUC5B MUC5AC

2.74e-0315982IPR006208
DomainCys_knot

MUC5B MUC5AC

2.74e-0315982PF00007
DomainC345C

C4A C4B

3.52e-0317982SM00643
DomainLCE

LCE3B LCE3A

3.52e-0317982PF14672
DomainLCE

LCE3B LCE3A

3.52e-0317982IPR028205
DomainEGF_CA

NELL2 CELSR1 HMCN2 LTBP4

3.90e-03122984SM00179
DomainFurin_repeat

EGFR RSPO2

3.95e-0318982IPR006212
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

3.95e-0318982IPR008930
Pubmed

Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.

TET2 CXXC5 TET1

2.45e-083102331433977
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

CXXC5 TET1 CXXC4

2.90e-0610102329276034
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

IL12RB1 VWF GRK6 EGFR LTBP4 VDR

4.23e-06143102620424473
Pubmed

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.

GAS1 LHX6 CDCA7 FGD3

5.88e-0640102427657450
Pubmed

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.

TET2 CELSR1 TET1

6.86e-0613102326989192
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

8.52e-06210227513696
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

8.52e-062102222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

8.52e-062102216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

8.52e-062102215998580
Pubmed

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways.

EGFR MUC5AC

8.52e-062102220525715
Pubmed

Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases.

TET2 TET1

8.52e-062102227362828
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

8.52e-062102219062096
Pubmed

Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors.

TET2 TET1

8.52e-062102230045709
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

8.52e-062102237146737
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

8.52e-062102219933335
Pubmed

Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.

TET2 TET1

8.52e-062102223415914
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

8.52e-062102214988081
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

8.52e-06210222459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

8.52e-062102217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

8.52e-062102212207352
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

8.52e-062102215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

8.52e-062102217621824
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

8.52e-062102224317696
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

8.52e-062102227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

8.52e-062102222387014
Pubmed

Increased expression of mucin 5AC mRNA and decreased expression of epidermal growth-factor receptor mRNA in gallstone patients.

EGFR MUC5AC

8.52e-062102218285671
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

8.52e-062102222391959
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

8.52e-062102235776514
Pubmed

Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.

TET2 TET1

8.52e-062102230540950
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

8.52e-062102223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

8.52e-062102223918728
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

8.52e-062102224327612
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

8.52e-06210223037333
Pubmed

Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation.

TET2 TET1

8.52e-062102232114381
Pubmed

Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development.

TET2 TET1

8.52e-062102235955629
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

8.52e-062102211726230
Pubmed

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells.

EGFR TET1

8.52e-062102227346347
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

8.52e-06210224216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

8.52e-06210226950384
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

8.52e-06210228660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

8.52e-06210228428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

8.52e-062102224638111
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

8.52e-062102221345967
Pubmed

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.

TET2 TET1

8.52e-062102224474761
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

8.52e-062102228607090
Pubmed

Cross-talk between EGFR and T-cadherin: EGFR activation promotes T-cadherin localization to intercellular contacts.

EGFR CDH13

8.52e-062102223411345
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

8.52e-06210222572548
Pubmed

The complement component C4 of mammals.

C4A C4B

8.52e-06210222302180
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

8.52e-062102222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

8.52e-062102218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

8.52e-062102229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

8.52e-06210226589636
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

8.52e-062102225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

8.52e-062102217728371
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

8.52e-062102231030254
Pubmed

Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination.

TET2 TET1

8.52e-062102230606231
Pubmed

Structure and organization of the C4 genes.

C4A C4B

8.52e-06210226149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

8.52e-06210226149581
Pubmed

Ten-eleven translocation 2 modulates allergic inflammation by 5-hydroxymethylcytosine remodeling of immunologic pathways.

TET2 TET1

8.52e-062102234165552
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

8.52e-062102223527003
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

8.52e-062102212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

8.52e-06210223542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

8.52e-06210222387317
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

8.52e-062102216540890
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

8.52e-062102216908004
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

8.52e-06210227365238
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

8.52e-062102227845589
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

8.52e-06210227391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

8.52e-062102217971360
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

8.52e-062102229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

8.52e-062102217971229
Pubmed

Diet-derived 25-hydroxyvitamin D3 activates vitamin D receptor target gene expression and suppresses EGFR mutant non-small cell lung cancer growth in vitro and in vivo.

EGFR VDR

8.52e-062102226654942
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

8.52e-06210226881182
Pubmed

Tet-mediated imprinting erasure in H19 locus following reprogramming of spermatogonial stem cells to induced pluripotent stem cells.

TET2 TET1

8.52e-062102226328763
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

8.52e-062102227435107
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

8.52e-062102226871672
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

8.52e-062102217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

8.52e-062102221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

8.52e-06210226978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

8.52e-062102235898513
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

8.52e-062102228873507
Pubmed

T-Cadherin is an auxiliary negative regulator of EGFR pathway activity in cutaneous squamous cell carcinoma: impact on cell motility.

EGFR CDH13

8.52e-062102222592160
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

8.52e-0621022276882
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

8.52e-06210226832377
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

8.52e-06210223794341
Pubmed

Clinical analysis of NSCLC patients reveals lack of association between EGFR mutation and TET1 downregulation.

EGFR TET1

8.52e-062102228776568
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

8.52e-062102211587997
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

8.52e-062102222785613
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

8.52e-062102232691186
Pubmed

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.

C4A C4B

8.52e-06210228390682
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

8.52e-062102234656442
Pubmed

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).

C4A C4B

8.52e-06210223902619
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

8.52e-06210227373044
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

8.52e-06210223696167
Pubmed

Structural insight into substrate preference for TET-mediated oxidation.

TET2 TET1

8.52e-062102226524525
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

8.52e-062102234058148
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

8.52e-06210221357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

8.52e-062102216098595
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

8.52e-062102215787745
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

8.52e-062102230026462
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL1 NBEA LRBA

4.21e-0696831230
GeneFamilyComplement system|Sushi domain containing

ITGB2 C4A C4B C8B

9.84e-0636684492
GeneFamilyZinc fingers CXXC-type

CXXC5 TET1 CXXC4

1.09e-0512683136
GeneFamilyNon-canonical poly(A) polymerases

TUT4 TUT1

2.89e-0476821318
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

4.93e-0496821234
GeneFamilyLate cornified envelope proteins

LCE3B LCE3A

2.05e-0318682627
GeneFamilyCD molecules|Mucins

MUC5B MUC5AC

2.79e-0321682648
GeneFamilyFibrinogen C domain containing

TNN TNR

3.95e-0325682554
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF KCP LAMB2 TECTA SSPOP NELL2 HMCN2 PXDNL TNN RSPO2 TNR LTBP4

1.64e-1119610212M3008
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF KCP LAMB2 TECTA SSPOP NELL2 HMCN2 TNN RSPO2 TNR LTBP4

2.31e-1019110211MM17059
CoexpressionNABA_CORE_MATRISOME

VWF KCP LAMB2 TECTA SSPOP NELL2 HMCN2 PXDNL TNN RSPO2 TNR LTBP4

8.18e-1027510212M5884
CoexpressionNABA_CORE_MATRISOME

VWF KCP LAMB2 TECTA SSPOP NELL2 HMCN2 TNN RSPO2 TNR LTBP4

8.80e-0927010211MM17057
CoexpressionNABA_MATRISOME

VWF P3H3 WNT8B KCP LAMB2 MUC5B TECTA SSPOP NELL2 HMCN2 PXDNL TNN RSPO2 CHRDL1 TNR LTBP4 MUC5AC

4.36e-07102610217M5889
CoexpressionNABA_MATRISOME

VWF P3H3 WNT8B KCP LAMB2 MUC5B TECTA SSPOP NELL2 HMCN2 TNN RSPO2 CHRDL1 TNR LTBP4 MUC5AC

1.73e-06100810216MM17056
CoexpressionSANSOM_APC_TARGETS_DN

IL12RB1 GBF1 ITGB2 LAPTM5 FCGBP C4A LTBP4 FGD3 VDR

1.34e-053661029M1432
CoexpressionVANTVEER_BREAST_CANCER_ESR1_UP

CXXC5 LAMB2 CELSR1 C4A LRBA FGD3

2.62e-051491026M393
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NBEA MUC5B CELSR1 FCGBP SYTL5 TMC5 MUC5AC

1.75e-071771027779ba86f53650772755b52460be03f18bb204e55
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NBEA MUC5B CELSR1 FCGBP SYTL5 TMC5 MUC5AC

1.75e-0717710270f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

NBEAL1 KCP NBEA GFRA2 RGS20 ZFHX3 FBLIM1

3.99e-07200102769edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT4 WASHC4 RUBCNL LAPTM5 ABLIM1 FCGBP

1.80e-0615910262881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NBEA MUC5B LRRC55 CRYBA2 TMC5 MUC5AC

3.25e-061761026dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHX6 EGFR CDCA7 SYTL5 CHRDL1 CDH13

3.35e-061771026b75f519d72611b293d9684f7dcfb1b70fbf54a90
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF KCP LAMB2 ABLIM1 SP5 LTBP4

3.69e-0618010262405aa5699a8d8cf4c6b3dca07510e774728ac50
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF KCP LAMB2 ABLIM1 SP5 LTBP4

3.69e-0618010269c47852c0a723e2f5cd6898afff4c31a0da06905
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF KCP LAMB2 ABLIM1 SP5 LTBP4

3.69e-061801026499d5fe71e0dc20cffdf85e3b3f14eb4e83e3a3d
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

NBEA MUC5B CELSR1 FCGBP TMC5 MUC5AC

3.94e-0618210263f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

NBEA MUC5B CELSR1 FCGBP TMC5 MUC5AC

4.06e-061831026940cbe298e9c53b5622af09264586ed823d3141f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHX6 EGFR CDCA7 SYTL5 CHRDL1 CDH13

4.19e-061841026e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHX6 SSPOP EGFR CDCA7 SYTL5 CHRDL1

4.19e-061841026ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 GRK6 ITGB2 ABLIM1 LPAR2 TNFAIP3

4.19e-0618410268fc047977fad38fcd26eebcc279a688efd342ed8
ToppCellfacs-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 CHRDL1 C4B FBLIM1 LTBP4

4.89e-061891026bdf8db938aa0863c4fed6fa99dcffd63c8c20c31
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GAS1 LAMB2 NELL2 RSPO2 LTBP4 CDH13

4.89e-061891026c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 GFRA2 C4B FBLIM1 LTBP4

4.89e-061891026e76dc36a01d8ad7590b3acc4c46abfcb76857448
ToppCelldroplet-Lung-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 GFRA2 C4B FBLIM1 LTBP4

5.04e-0619010260b7200897b2c389632c9b1ee37e272b811555dbc
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 GFRA2 C4B FBLIM1 LTBP4

5.19e-0619110268a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 EGFR C4B FBLIM1 LTBP4

5.19e-061911026997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCelldroplet-Lung-21m-Mesenchymal|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 GFRA2 C4B FBLIM1 LTBP4

5.19e-06191102610a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCellfacs-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 GAS1 EGFR C4B FBLIM1 LTBP4

5.35e-0619210268df15085b35b86f39debd933284cb703c5dd63c2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCP LHX6 SYTL5 RSPO2 FBLIM1 CDH13

5.68e-06194102683863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRGC2 ITGB2 LAPTM5 NELL2 CDCA7 TNFAIP3

5.68e-061941026c57cf3cc9fc1a682019090369fc1d3adbf37c371
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GFRA4 CORIN ZFHX3 C4B FBLIM1 CDH13

5.85e-06195102643d372373367b71243c6ea958aedccde4478618f
ToppCellCOVID-19-Lymphoid-CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

TNFRSF4 LAPTM5 ABLIM1 NELL2 LPAR2 TNFAIP3

6.02e-06196102628515d8e2f02366fa0ac1bea251a7a3f659c98c7
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 GAS1 LAMB2 EGFR C4B LTBP4

6.02e-061961026b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 GAS1 LAMB2 EGFR C4B LTBP4

6.02e-061961026787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGB2 LAPTM5 ABLIM1 NELL2 TNFAIP3 FGD3

6.38e-0619810260dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EGFR TET1 CHRDL1 ENDOU C4B LTBP4

6.57e-061991026a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CXXC5 CD320 ITGB2 LAPTM5 VOPP1 DMRT2

6.57e-061991026f197ab861767ee06aa47b86c537fb3d8c2b2bc3e
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

NBEA MUC5B FCGBP SYTL5 TMC5 MUC5AC

6.76e-062001026292c63693eb7f435335a8cfba07aa35b72139393
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRRC4B RFNG HMCN2 TNN USP35

1.15e-0512810252cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellSevere-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT4 WASHC4 RUBCNL ABLIM1 C8B

1.77e-051401025683ee5e103f0c68cbbec019249404d381dbc39f3
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TUT4 WASHC4 RUBCNL ABLIM1 MRNIP

1.97e-051431025bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-3|TCGA-Colorectal / Sample_Type by Project: Shred V9

LRRC4B TNFRSF4 GJD3 LPAR2 CTU1

2.98e-051561025b464871ad7c8ce0d58013a27996639eac1e526d8
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 CATSPERD ITGB2 LAPTM5 CELSR1

3.08e-051571025ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B RAD51AP2 CELSR1 TMC5 MUC5AC

3.27e-05159102560b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IL12RB1 ITGB2 LAPTM5 DLGAP3 FCGBP

3.37e-0516010257f1b58641ba149d20420fafad34ba78a65a2c701
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CATSPERD TAFA3 ITGB2 LAPTM5 TNFAIP3

3.58e-05162102504ccd3d216f8f41afd3434a61264f03d6324db35
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

IL12RB1 CATSPERD NELL2 RGS20 CDH13

3.68e-05163102519c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL12RB1 TAFA3 ITGB2 LAPTM5 VDR

3.68e-051631025476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCell10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

CXXC5 ITGB2 GJD3 ZFHX3 TNR

3.79e-05164102536e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LHX6 SYTL5 ARMCX6 CDH13

3.80e-0582102442017b8ace6f142a8358213c95a2632226c3a867
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP SYTL5 TMC5 MUC5AC

4.25e-051681025b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP SYTL5 TMC5 MUC5AC

4.25e-0516810250757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B FCGBP SYTL5 TMC5 MUC5AC

4.25e-051681025a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 LRRC4B ITGB2 USP35 TNR

4.50e-05170102528fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 LRRC4B ITGB2 USP35 TNR

4.50e-051701025239cb4b801b2d71a6facb386f2684c0851504151
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 ITGB2 TNFRSF4 LAPTM5 TNFAIP3

4.76e-0517210256c7d03393a60dab954054e34ea842cc77412eb19
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LAMB2 MUC5B SYTL5 ZFHX3 MUC5AC

4.76e-0517210250be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellprimary_auditory_cortex_(A1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZAN CATSPERD TMEM52B HMCN2 CDH13

4.76e-05172102520ea9db009370aa6235365ce93e153eb5b28db94
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GAS1 ESYT3 NELL2 CHRDL1 C4B

4.89e-051731025ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 GFRA2 TNN ZFHX3 TMC5

4.89e-0517310252415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GAS1 ESYT3 NELL2 CHRDL1 C4B

4.89e-0517310253725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NBEA MUC5B DMRT2 TMC5 MUC5AC

4.89e-051731025464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 GFRA2 TNN ZFHX3 TMC5

4.89e-0517310252acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRRC4B GFRA4 CHRDL1 FBLIM1 CDH13

4.89e-0517310255c55e1e27e9e3e77600d378cc87b51cc73907527
ToppCellInt-URO-Lymphocyte-T_NK-NK_CD56bright|Int-URO / Disease, Lineage and Cell Type

TRGC2 CXXC5 CD320 TNFRSF4 CORIN

5.02e-05174102593c7acd5941a5f235ec4c57461f78ee2871e7336
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 TRGC2 ITGB2 LAPTM5 NELL2

5.02e-05174102547e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

NBEA MUC5B FCGBP CXXC4 MUC5AC

5.02e-0517410257d2f802f493f19a068e097b2909a9000e2160266
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL12RB1 ITGB2 LAPTM5 CELSR1 TNFAIP3

5.02e-0517410257c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL12RB1 TRGC2 ITGB2 LAPTM5 NELL2

5.02e-051741025a92c745d20633909db0f08effa13fc738fda79a6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC5B FCGBP SYTL5 CROCC2 MUC5AC

5.45e-0517710252af09028014f4ec3b7d2a4c286f1ae5e84a9f590
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 ITGB2 LAPTM5 CELSR1 TNFAIP3

5.45e-05177102531201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 ITGB2 LAPTM5 CELSR1 TNFAIP3

5.45e-05177102589d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TUT4 NBEAL1 ABLIM1 NELL2 CHRDL1

5.45e-051771025db6de487ef7976b444afadbf3ac60b3259925566
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

NBEA MUC5B FCGBP TMC5 MUC5AC

5.60e-051781025f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHX6 EGFR CDCA7 SYTL5 CHRDL1

5.60e-051781025f332c7a96844abecf05ca057480fbea9296688a2
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL12RB1 TRGC2 ITGB2 LAPTM5 NELL2

5.60e-051781025f52f837e948deb6a2d031325f49891bca8d375da
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

NBEA MUC5B CELSR1 FCGBP MUC5AC

5.75e-0517910251fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CXXC5 MUC5B CDCA7 TET1 FGD3

5.75e-051791025d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-TRDV2/TRGV9_gdT|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRGC2 ITGB2 LAPTM5 TNFAIP3 FGD3

5.75e-051791025f7d3d37505893ae55065c89d957084602729decc
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 TNFRSF4 LAPTM5 CELSR1 TNFAIP3

5.75e-0517910256f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF NBEA ESYT3 ARMCX6 LTBP4

5.90e-051801025baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

NBEA MUC5B FCGBP TMC5 MUC5AC

5.90e-051801025a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellfacs-Heart-RA-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 ITGB2 LAPTM5 CELSR1 TNFAIP3

5.90e-0518010259be0af61d496a29d737bb772ad09864797994299
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL12RB1 TRGC2 NBEA TNFRSF4 CELSR1

5.90e-05180102512f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL12RB1 TRGC2 NBEA TNFRSF4 CELSR1

5.90e-0518010251bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF NBEA ESYT3 ARMCX6 LTBP4

5.90e-0518010252d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EGFR CDCA7 SYTL5 CHRDL1 TMC5

5.90e-051801025392bc71a69653ba12de31bed4e9357f181094641
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL12RB1 TRGC2 NBEA TNFRSF4 CELSR1

5.90e-0518010252a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF NBEA ESYT3 ARMCX6 LTBP4

5.90e-0518010250f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 GRK6 RUBCNL CXXC5 ABLIM1

6.06e-05181102546de8c18e4ec8dc9d07f7c8cc7b5f48b9c613aae
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P3H3 GAS1 HMCN2 C4B LTBP4

6.06e-0518110253462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P3H3 GAS1 HMCN2 C4B LTBP4

6.06e-0518110256730e249cac55ae892cc567d9211615882f3dab4
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF LAMB2 ARMCX6 LTBP4 CDH13

6.06e-051811025136b0c60680068838d184d32aa99d7bea8718dbc
ToppCellBronchial_Biopsy-Immune-T_and_NK|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

IL12RB1 TRGC2 ITGB2 TMEM52B LAPTM5

6.22e-051821025dab2ea0298e26649a923c34d4699e437e9385b90
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LHX6 EGFR CDCA7 SYTL5 CHRDL1

6.38e-051831025f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCellBasal|World / shred by cell class for mouse tongue

GAS1 CELSR1 ZFHX3 LTBP4 CDH13

6.38e-051831025c6729a207526ff4aa48176207b9353176f631fea
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT8B TECTA TNN CORIN CDH13

6.38e-051831025877559962b2b073fc2a9f1b64a76e17895e40a97
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 CATSPERD ITGB2 TNFRSF4 LAPTM5

6.38e-051831025ac70a6ec9270b1bfe089702262d4575a6c42afb4
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRK6 ITGB2 LAPTM5 NELL2 TNFAIP3

6.55e-051841025c80acd6a81a3633d72813a77223879d0be254f93
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|World / Cell class and subclass of bone marrow stroma cells in homeostatis

VWF LHX6 ABLIM1 LTBP4 CDH13

6.55e-0518410257e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCP LHX6 HMCN2 FBLIM1 CDH13

6.55e-0518410257f6c8912677764d438ab0555faca344d74c2f483
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-CD8_Tmem|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRK6 TRGC2 ITGB2 LAPTM5 NELL2

6.55e-05184102561e2a8b9a42e5788fb4e47c77cc5de65420acbfa
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC5B FCGBP SYTL5 TMC5 MUC5AC

6.55e-051841025d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NBEA MUC5B FCGBP TMC5 MUC5AC

6.55e-05184102501c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF CD320 LHX6 TNFRSF4 LRRC55

6.72e-051851025a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF TUT1 CD320 LHX6 TNFRSF4

6.72e-0518510250ab1be455f2cd883c9d1522ca78112c37833352e
ComputationalTrachea genes.

VWF GAS1 LAMB2 MUC5B LAPTM5 ABLIM1 FCGBP EGFR TNFAIP3

1.71e-04415539MODULE_6
Diseasebreast cancer (is_marker_for)

TET2 TUT4 EGFR ZFHX3 CDH13 VDR

3.87e-05185996DOID:1612 (is_marker_for)
Diseasemucinous adenocarcinoma (is_marker_for)

ZFHX3 MUC5AC

1.11e-045992DOID:3030 (is_marker_for)
DiseaseComplement deficiency disease

C4A C4B C8B

1.86e-0433993C0272242
DiseaseGraves' disease (is_implicated_in)

C4A C4B VDR

3.07e-0439993DOID:12361 (is_implicated_in)
DiseaseNeoplasm Recurrence, Local

TET2 EGFR LTBP4

3.07e-0439993C0027643
Diseasealpha-2-macroglobulin measurement

TET2 GRK6

3.08e-048992EFO_0020138
DiseaseAutoimmune Diseases

TNFRSF4 C4B TNFAIP3

3.82e-0442993C0004364
Diseaseallergic rhinitis (biomarker_via_orthology)

ITGB2 MUC5AC

4.93e-0410992DOID:4481 (biomarker_via_orthology)
Diseasecortical surface area measurement

RABEP2 TET2 ZAN NBEAL1 GAS1 FBXO16 CELSR1 DMRT2 EGFR RSPO2 ZFHX3 USP35 ATXN10

5.59e-0413459913EFO_0010736
Diseasepulmonary fibrosis

MUC5B MUC5AC

6.01e-0411992EFO_0009448
Diseasepulmonary fibrosis (biomarker_via_orthology)

VWF EGFR MUC5AC

6.40e-0450993DOID:3770 (biomarker_via_orthology)
Diseaseneuroticism measurement, cognitive function measurement

TET2 NBEAL1 GRK6 GFRA2 CXXC4 ZFHX3 TNR CDH13

6.48e-04566998EFO_0007660, EFO_0008354
Diseaseprostate cancer (is_implicated_in)

EGFR ZFHX3 CDH13 VDR

6.61e-04117994DOID:10283 (is_implicated_in)
Diseaselobe attachment

GAS1 NBEA ATXN10 LRBA FGD3

6.79e-04207995EFO_0007667
Diseasebasal cell carcinoma (is_implicated_in)

PTCH2 VDR

7.20e-0412992DOID:2513 (is_implicated_in)
Diseasesevere acute respiratory syndrome, COVID-19

CATSPERD P3H3 ABLIM1 ZFHX3 FBLIM1 TNR CDH13

7.85e-04447997EFO_0000694, MONDO_0100096
Diseaseneuroimaging measurement

NBEAL1 GAS1 CXXC5 RNF34 ABLIM1 NELL2 CELSR1 EGFR GJD3 RSPO2 TMC5

9.21e-0410699911EFO_0004346
DiseaseTinnitus

GRK6 CDCA7 CTU1 CDH13

9.80e-04130994HP_0000360
Diseaseurate measurement, spine bone mineral density

EGFR MARK4 CDH13

9.89e-0458993EFO_0004531, EFO_0007701
DiseaseProstatic Neoplasms

TET2 LAMB2 EGFR BAZ2A SP5 ZFHX3 CDH13 VDR

1.12e-03616998C0033578
DiseaseMalignant neoplasm of prostate

TET2 LAMB2 EGFR BAZ2A SP5 ZFHX3 CDH13 VDR

1.12e-03616998C0376358
Diseasepsoriasis vulgaris

LCE3B LCE3A TNFAIP3

1.14e-0361993EFO_1001494
Diseaselung non-small cell carcinoma (is_implicated_in)

TET2 EGFR ZFHX3 CDH13

1.26e-03139994DOID:3908 (is_implicated_in)
DiseaseDermatitis

ITGB2 EGFR

1.30e-0316992C0011603
Diseasecholangiocarcinoma (is_marker_for)

MUC5B TNFAIP3 MUC5AC

1.32e-0364993DOID:4947 (is_marker_for)
Diseasepeak expiratory flow

TET2 CXXC5 LAPTM5 MLLT6 ATXN10 LTBP4 VDR

1.46e-03498997EFO_0009718
DiseaseAntibody Deficiency Syndrome

C4A C8B

1.47e-0317992C0003257
Diseasemaximum cigarettes per day measurement

EGFR TMC5

1.65e-0318992EFO_0009264
DiseaseLupus Erythematosus, Systemic

C4A C4B TNFAIP3

1.77e-0371993C0024141
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

VWF EGFR

1.84e-0319992DOID:9744 (biomarker_via_orthology)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

TET2 EGFR TNFAIP3

2.00e-0374993DOID:3748 (is_marker_for)
Diseaseanti-Mullerian hormone measurement

CDCA7 TNN

2.04e-0320992EFO_0004769
Diseasepsoriasis, type 2 diabetes mellitus

LCE3B LCE3A TNFAIP3

2.08e-0375993EFO_0000676, MONDO_0005148
Diseasevitiligo (is_implicated_in)

C4A VDR

2.24e-0321992DOID:12306 (is_implicated_in)
Diseasenicotine dependence

GFRA2 DLGAP3 LTBP4

2.32e-0378993EFO_0003768
DiseaseImmunologic Deficiency Syndromes

C4A C8B

2.69e-0323992C0021051
Diseaselow density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram

GFRA2 ZFHX3

2.93e-0324992EFO_0004611, EFO_0006329, EFO_0007871
DiseaseBehcet Syndrome

ITGB2 C4A

2.93e-0324992C0004943
Diseaseprostate cancer, disease progression measurement

IL12RB1 RFNG

2.93e-0324992EFO_0008336, MONDO_0008315
Diseasesystemic scleroderma

IL12RB1 KCP TNFAIP3

2.96e-0385993EFO_0000717
Diseasebreast carcinoma (is_implicated_in)

EGFR CDH13

3.18e-0325992DOID:3459 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CRITKDNRRHCQACR

VDR

66

P11473
DNRRHCQACRLKRCV

VDR

71

P11473
RENTIRNCSCSADIR

C21orf62

36

Q9NYP8
CLRRCLSVLINGCRN

ESYT3

766

A0FGR9
CCLRCIQTRDTNFGT

BUD31

101

P41223
CRKCESQERAARVRC

MLLT6

51

P55198
QLCRRCKTVCQFRAS

CATSPERD

761

Q86XM0
RLCRSTRQRAACAQL

C4B

1716

P0C0L5
RVTFNGRDCLCQLCA

ABLIM1

196

O14639
CNTTRRRLTCAKCVQ

ATG14

46

Q6ZNE5
RCLRNACIECSVNQN

ATXN10

86

Q9UBB4
QTLERCRSAAQVCLC

BAZ2A

1646

Q9UIF9
RCRLLSDCANVCERG

CRYBA2

26

P53672
CELLSRNRTHVACQC

CELSR1

2431

Q9NYQ6
RVQVCSCRNSKVDCN

CDH13

676

P55290
VCRETVSRCCNSFLQ

ARMCX6

201

Q7L4S7
RVDCNTCTCRNRRWE

MUC5B

871

Q9HC84
KRICCINRQSRTTCV

NBEAL1

471

Q6ZS30
CNCSSIQCNVRDSRK

RAD51AP2

351

Q09MP3
FQTATCRRCSACRAC

RUBCNL

616

Q9H714
LCCTRQEARARLQAQ

RABEP2

421

Q9H5N1
NTNCSAVRTRQALCC

RFNG

111

Q9Y644
RAALRRADCLTQCAA

P3H3

116

Q8IVL6
RSRVLRCCSCRLFQA

MRNIP

6

Q6NTE8
LCTCRNQVVDCSSQR

LRRC55

41

Q6ZSA7
RTFRRLLCCACLRQS

LPAR2

301

Q9HBW0
LLCCACLRQSTRESV

LPAR2

306

Q9HBW0
SICRNLNDRAVCSCR

NELL2

411

Q99435
ECRVRNLCQHACRNT

HMCN2

4866

Q8NDA2
NCSRLACLAGELRCT

CD320

126

Q9NPF0
KFNRDAACQCDRRCL

ENDOU

31

P21128
CCRCHQKVRQRARDA

FAM205A

46

Q6ZU69
RQCLRLVCAVAVRNC

LRBA

1441

P50851
ISDRLGCRRCQCNAR

LAMB2

461

P55268
ECSVCRTSLRQQNSC

LHX6

96

Q9UPM6
CTEARRRCDRDSRCN

GAS1

166

P54826
EHRCQCCQELRTSLR

MUC5AC

5576

P98088
AENSRQSRVCRDCFL

FGD3

571

Q5JSP0
CAPCRRRINCEQCSS

CXXC5

266

Q7LFL8
RRINCEQCSSCRNRK

CXXC5

271

Q7LFL8
CCCHRPQESQRRTSR

FBXO38

776

Q6PIJ6
VLPQCECRCRDQSRD

ITGB2

441

P05107
QDCCADCRSRGQFRA

PXDNL

1296

A1KZ92
AVALSCQCALCRRST

CGB2

101

Q6NT52
RDCVSCRNVSRGREC

EGFR

521

P00533
DCQCANCLLVVERQR

DMRT2

146

Q9Y5R5
ICSENGNVLCSRVRC

CHRDL1

66

Q9BU40
FCSCQDQACAERRRQ

GFRA2

221

O00451
LNFCERSRVCRCARA

GFRA4

121

Q9GZZ7
LSEAECRCARAQSRV

CROCC2

1396

H7BZ55
ADELCQRRCTCNGAT

FCGBP

816

Q9Y6R7
ACSRCGALASRALCQ

CTU1

286

Q7Z7A3
TRRSSSVDQARINCC

DLGAP3

426

O95886
AQLRRTIECCRTNLC

BMPR1A

116

P36894
KRLINCGVCSSCRNR

CXXC4

146

Q9H2H0
KCRSGQCVLASRRCD

CORIN

586

Q9Y5Q5
QCVLASRRCDGQADC

CORIN

591

Q9Y5Q5
QCAPCALRARRARRC

GJD3

121

Q8N144
LLSRQGAACRTSECC

IL12RB1

16

P42701
ALRQATAAARCRCRQ

MARK4

676

Q96L34
ARCLNTDGSFRCICR

LTBP4

1591

Q8N2S1
AQCFTCRTCRRQLAG

FBLIM1

206

Q8WUP2
CLCCDARRQVRMQAL

GBF1

1551

Q92538
RSHRCRCQSSNSCDR

LCE3A

56

Q5TA76
CRSHRCRRQSSNSCD

LCE3B

61

Q5TA77
LLERCSLSQQKFCCR

FBXO16

61

Q8IX29
LLQRLFSRQDCCGNC

GRK6

551

P43250
VCAQTGRCVNRRLLC

C8B

126

P07358
RLCRSTRQRAACAQL

C4A

1716

P0C0L4
CSCSNQASRVICTRR

LRRC4B

61

Q9NT99
CQACSLRVCRECRVA

SYTL5

81

Q8TDW5
CEVIAAHRCCNRNRI

TAFA3

46

Q7Z5A8
ATARRCRRCRCPNCQ

SP5

266

Q6BEB4
SLCSCSCNVGIRRRF

SSPOP

2996

A2VEC9
VTCANRCPRRCSDLQ

SSPOP

4071

A2VEC9
IITCCLLRRTAFCCN

TRGC2

171

P03986
STVRQTCCCFNVRIA

LAPTM5

6

Q13571
CSCSCLTVRNQEDQR

RGS20

216

O76081
RLQERGLCVRCSCQA

KCP

386

Q6ZWJ8
LCRCLSGNVQCLARR

KCP

626

Q6ZWJ8
RRCLCLDGSVSCQRL

KCP

691

Q6ZWJ8
FSNSRENRRCLLQCS

NBEA

876

Q8NFP9
CCVAVRNCLECRQRQ

NBEA

1476

Q8NFP9
RRHCQRLDVLCCFSS

PTCH2

556

Q9Y6C5
LCRCSDHCRNRVVQK

SETMAR

121

Q53H47
NRCARCRIENCDSCF

RSPO2

91

Q6UXX9
RRCTLNENRTCTCQG

TET1

1551

Q8NFU7
ICNCSFCRQRDGRCA

CDCA7

326

Q9BWT1
TCRSDVSLCNLERCS

C12orf40

621

Q86WS4
TRRCRCFRRNVIQCD

TECTA

1446

O75443
CCAVRCEQCRRRVTK

WNT8B

316

Q93098
CGSRCCVRALSIQRL

VOPP1

46

Q96AW1
LCEVARLRQNADQCC

VWF

2306

P04275
CARASCKNILACRSE

TNFAIP3

716

P21580
CSAQRCCQGVTDLSR

TNN

126

Q9UQP3
CSVCSVLQENLRRCS

RNF34

86

Q969K3
TSRVAGRLQNCCRAA

TUT1

556

Q9H6E5
SVSCCKQRNNVCTRA

STPG1

156

Q5TH74
TRICCLCCLNVSSRE

USP35

576

Q9P2H5
NCNRHLRKNCCTSVR

ZNF556

131

Q9HAH1
REVSVLRDQCNANCC

TNR

146

Q92752
RDCKCTLACQQFRVR

RP2

106

O75695
TSLCFRCCCLSRQQN

TMEM52B

61

Q4KMG9
DCSESRVLRCKTNCR

ZNF518A

1226

Q6AHZ1
KQLCTATQDTVCRCR

TNFRSF4

96

P43489
SELRERVQTQCDCCF

WASHC4

591

Q2M389
SSLCRLRLRCRAAAC

SLC30A9

16

Q6PML9
NCCIQCLNSISRAYR

TMC5

401

Q6UXY8
TQDRCATRRCRERCP

TUT4

1621

Q5TAX3
RRCALNEERTCACQG

TET2

1261

Q6N021
RAATMCCLCQRSFRT

ZFHX3

1426

Q15911
KELCVCESNNRIRCQ

ZAN

1501

Q9Y493
DCSQRCTCASSRILL

ZAN

2671

Q9Y493
DPSRSRLCSICCRRN

VN1R2

371

Q8NFZ6