Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	3.33e-05	431	75	9	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR1N2 GHR MET OR11L1 OR52K1 CSF2RA ADGRG2 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 IL17RD GPR160 OR1J2	1.29e-04	1353	75	15	GO:0004888
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1C CACNA1D	1.38e-04	5	75	2	GO:0086007
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	RELN SACS CLTC	4.22e-04	39	75	3	GO:0070325
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR1N2 OR11L1 OR52K1 ADGRG2 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 GPR160 OR1J2	4.41e-04	884	75	11	GO:0004930
GeneOntologyBiologicalProcess	actin filament-based process	FMNL3 CACNA1C GPM6B CACNA1D MET MYH2 NF1 NCKAP1 TBCK SCN8A PIP5K1A PRKCQ STRIP1	2.25e-05	912	75	13	GO:0030029
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	2.64e-05	432	75	9	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	4.68e-05	465	75	9	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	6.47e-05	485	75	9	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	1.17e-04	524	75	9	GO:0009593
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	CACNA1C CACNA1D	1.30e-04	5	75	2	GO:1904879
GeneOntologyBiologicalProcess	smooth muscle contraction involved in micturition	CACNA1C KCNMA1	1.30e-04	5	75	2	GO:0060083
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	1.61e-04	547	75	9	GO:0007606
MousePheno	abnormal endplate potential	STXBP5L SCN8A PRKCQ	4.20e-05	17	57	3	MP:0002914
MousePheno	abnormal hindbrain development	MET RGL1 RELN IPO9 IFT172 SCN8A	5.26e-05	164	57	6	MP:0006108
Domain	ARM-type_fold	FMNL3 STK36 THADA IPO9 NF1 PSME4 IFT172 CLTC USP24 MIF4GD FRYL RSPRY1	8.43e-09	339	74	12	IPR016024
Domain	Olfact_rcpt	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	2.44e-05	393	74	9	IPR000725
Domain	CAC1F_C	CACNA1C CACNA1D	4.63e-05	3	74	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D	4.63e-05	3	74	2	PF16885
Domain	VDCC_L_a1su	CACNA1C CACNA1D	9.24e-05	4	74	2	IPR005446
Domain	GPCR_Rhodpsn_7TM	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 GPR160 OR1J2	2.99e-04	670	74	10	IPR017452
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D	3.21e-04	7	74	2	IPR014873
Domain	GPHH	CACNA1C CACNA1D	3.21e-04	7	74	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D	3.21e-04	7	74	2	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1D	3.21e-04	7	74	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D	3.21e-04	7	74	2	PF08763
Domain	G_PROTEIN_RECEP_F1_1	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 GPR160 OR1J2	3.56e-04	685	74	10	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 GPR160 OR1J2	3.81e-04	691	74	10	PS50262
Domain	GPCR_Rhodpsn	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 GPR160 OR1J2	3.86e-04	692	74	10	IPR000276
Domain	VDCCAlpha1	CACNA1C CACNA1D	6.83e-04	10	74	2	IPR002077
Domain	ARM-like	STK36 IPO9 NF1 PSME4 FRYL RSPRY1	7.03e-04	270	74	6	IPR011989
Domain	Ion_trans_dom	CACNA1C CACNA1D SCN8A KCNMA1	1.09e-03	114	74	4	IPR005821
Domain	Ion_trans	CACNA1C CACNA1D SCN8A KCNMA1	1.09e-03	114	74	4	PF00520
Domain	7tm_1	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	1.38e-03	677	74	9	PF00001
Domain	Channel_four-helix_dom	CACNA1C CACNA1D SCN8A	1.50e-03	57	74	3	IPR027359
Domain	-	CACNA1C CACNA1D SCN8A	1.50e-03	57	74	3	1.20.120.350
Domain	-	STK36 IPO9 NF1 PSME4 FRYL	1.88e-03	222	74	5	1.25.10.10
Domain	EF-hand-dom_pair	EFHC2 CACNA1C MICU3 EHD1 SCN8A	5.62e-03	287	74	5	IPR011992
Pathway	REACTOME_SENSORY_PERCEPTION	OR1N2 CACNA1D OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 KCNMA1 PRKCQ OR52K2 OR1J2	2.07e-05	636	63	12	M41834
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR6C3 OR52K2 OR1J2	9.14e-05	417	63	9	M4072
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNA1C GPM6B NF1 SACS STXBP5L CDS2 KCNMA1 STRIP1	9.47e-07	347	76	8	17114649
Pubmed	Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.	CACNA1C CACNA1D RELN SCN8A	2.93e-06	45	76	4	25979088
Pubmed	Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology.	CACNA1C EZH2	4.71e-06	2	76	2	29501388
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	4.71e-06	2	76	2	21054386
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	4.71e-06	2	76	2	24086669
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	4.71e-06	2	76	2	26049024
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	4.71e-06	2	76	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	4.71e-06	2	76	2	16706838
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	4.71e-06	2	76	2	23761887
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	4.71e-06	2	76	2	14981074
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	4.71e-06	2	76	2	25292336
Pubmed	Loss of histone lysine methyltransferase EZH2 confers resistance to tyrosine kinase inhibitors in non-small cell lung cancer.	MET EZH2	4.71e-06	2	76	2	32920200
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	4.71e-06	2	76	2	17526649
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	4.71e-06	2	76	2	12606379
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	4.71e-06	2	76	2	24941892
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	4.71e-06	2	76	2	22826131
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	4.71e-06	2	76	2	24470632
Pubmed	TSRC1, a widely expressed gene containing seven thrombospondin type I repeats.	SCN8A ADAMTSL4	4.71e-06	2	76	2	12706885
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	4.71e-06	2	76	2	24760982
Pubmed	CaV1.3 L-type channels, maxiK Ca(2+)-dependent K(+) channels and bestrophin-1 regulate rhythmic photoreceptor outer segment phagocytosis by retinal pigment epithelial cells.	CACNA1D KCNMA1	4.71e-06	2	76	2	24407175
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	4.71e-06	2	76	2	20014384
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	4.71e-06	2	76	2	30001160
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	4.71e-06	2	76	2	21352396
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	4.71e-06	2	76	2	17409250
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	4.71e-06	2	76	2	16267232
Pubmed	Two classes of outer hair cells along the tonotopic axis of the cochlea.	CACNA1D KCNMA1	4.71e-06	2	76	2	17074442
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	4.71e-06	2	76	2	24996399
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	4.71e-06	2	76	2	24849370
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	4.71e-06	2	76	2	17015854
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	4.71e-06	2	76	2	24848473
Pubmed	Activation of Cav1.2 and BKCa is involved in the downregulation of caffeine-induced contraction in mice mesenteric arteries.	CACNA1C KCNMA1	4.71e-06	2	76	2	31194991
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR6C3 OR52K2	9.84e-06	340	76	7	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR6C3 OR52K2	9.84e-06	340	76	7	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR6C3 OR52K2	1.04e-05	343	76	7	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR6C3 OR52K2	1.10e-05	346	76	7	14611657
Pubmed	Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas.	NF1 EZH2	1.41e-05	3	76	2	31431463
Pubmed	Expression and inhibition of BRD4, EZH2 and TOP2A in neurofibromas and malignant peripheral nerve sheath tumors.	BRD4 EZH2	1.41e-05	3	76	2	28813519
Pubmed	EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes.	BRD4 EZH2	1.41e-05	3	76	2	37747726
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D	1.41e-05	3	76	2	17767505
Pubmed	BRD4 Regulates EZH2 Transcription through Upregulation of C-MYC and Represents a Novel Therapeutic Target in Bladder Cancer.	BRD4 EZH2	1.41e-05	3	76	2	26939702
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D	1.41e-05	3	76	2	2173707
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	1.41e-05	3	76	2	26831068
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	1.41e-05	3	76	2	23338940
Pubmed	The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.	CACNA1C CACNA1D	1.41e-05	3	76	2	19351867
Pubmed	Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.	CACNA1C CACNA1D	1.41e-05	3	76	2	21832054
Pubmed	Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex.	RELN EZH2	1.41e-05	3	76	2	26499080
Pubmed	Contribution of Ion Channels in Calcium Signaling Regulating Phagocytosis: MaxiK, Cav1.3 and Bestrophin-1.	CACNA1D KCNMA1	1.41e-05	3	76	2	26427483
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1D	1.41e-05	3	76	2	17289261
Pubmed	Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.	CACNA1C CACNA1D	1.41e-05	3	76	2	23973784
Pubmed	MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.	CACNA1C CACNA1D	1.41e-05	3	76	2	31302118
Pubmed	Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.	CACNA1C CACNA1D	1.41e-05	3	76	2	23045342
Pubmed	Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.	MET NF1	1.41e-05	3	76	2	17348023
Pubmed	Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.	CACNA1C CACNA1D	1.41e-05	3	76	2	24934288
Pubmed	DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.	ZBTB17 ZNF460 KLHL36 BRD4 CDS2 EZH2 ADAMTSL4	1.53e-05	364	76	7	31391242
Pubmed	The human olfactory receptor gene family.	OR1N2 OR11L1 OR52K1 OR51I1 OR5B2 OR5B17 OR52K2 OR1J2	2.43e-05	541	76	8	14983052
Pubmed	Identification of a novel function of the clathrin-coated structure at the plasma membrane in facilitating GM-CSF receptor-mediated activation of JAK2.	CSF2RA CLTC	2.82e-05	4	76	2	22935703
Pubmed	An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB.	NF1 EZH2	2.82e-05	4	76	2	20154697
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1D	2.82e-05	4	76	2	20937870
Pubmed	Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.	CACNA1C CACNA1D	2.82e-05	4	76	2	17110593
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1C CACNA1D	4.69e-05	5	76	2	11296258
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1C CACNA1D	4.69e-05	5	76	2	15451373
Pubmed	Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.	CACNA1C CACNA1D	4.69e-05	5	76	2	31663850
Pubmed	Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis.	CSF2RA EZH2	4.69e-05	5	76	2	34533976
Pubmed	Voltage-gated calcium channels in developing GnRH-1 neuronal system in the mouse.	CACNA1C CACNA1D	7.03e-05	6	76	2	16029198
Pubmed	Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.	CACNA1C CACNA1D	7.03e-05	6	76	2	21224388
Pubmed	Grb10/Nedd4-mediated multiubiquitination of the insulin-like growth factor receptor regulates receptor internalization.	CLTC LAMP1	7.03e-05	6	76	2	18286479
Pubmed	L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins.	CACNA1C CACNA1D	7.03e-05	6	76	2	23734214
Pubmed	Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments.	MYH2 NF1	7.03e-05	6	76	2	8808709
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1D	9.83e-05	7	76	2	12900400
Pubmed	EZH2-CCF-cGAS Axis Promotes Breast Cancer Metastasis.	USP24 EZH2	9.83e-05	7	76	2	35163710
Pubmed	The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.	MET BRD4	1.31e-04	8	76	2	23752591
Pubmed	Interleukin-1 hyperproduction by in vitro activated peripheral macrophages from cerebellar mutant mice.	RELN SCN8A	1.31e-04	8	76	2	2230805
Pubmed	Chromosome localization of two new mammalian kinases related to yeast and fly chromosome segregation-regulators.	MYH2 NF1	1.31e-04	8	76	2	9434955
Pubmed	Cloning and expression analysis of murine phospholipase D1.	MYH2 NF1	1.31e-04	8	76	2	9307024
Pubmed	Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.	MET ADGRG2 CLTC	1.33e-04	45	76	3	19581412
Pubmed	HiPLA: High-throughput imaging proximity ligation assay.	IPO9 BRD4 EZH2	1.42e-04	46	76	3	30419336
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	GHR MET NF1	1.52e-04	47	76	3	8812413
Pubmed	Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo.	CLTC PIP5K1A	1.68e-04	9	76	2	22976293
Pubmed	BRAF activates PAX3 to control muscle precursor cell migration during forelimb muscle development.	MET MYH2	1.68e-04	9	76	2	27906130
Pubmed	Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse.	NCKAP1 IFT172	1.68e-04	9	76	2	22384391
Pubmed	Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29.	EHD1 CLTC	1.68e-04	9	76	2	11423532
Pubmed	Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.	NCKAP1 CLTC KCNMA1	2.05e-04	52	76	3	20114047
Pubmed	Developmental origin and morphogenesis of the diaphragm, an essential mammalian muscle.	MET MYH2	2.10e-04	10	76	2	29679560
Pubmed	Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.	RELN SCN8A	2.10e-04	10	76	2	1565842
Pubmed	Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.	GPX6 PRKCQ EZH2	2.17e-04	53	76	3	36265442
Pubmed	Defining the membrane proteome of NK cells.	ACSL3 IPO9 NF1 CDS2 EHD1 CLTC LAMP1 ADAR ZDHHC13 LRRC8D	2.24e-04	1168	76	10	19946888
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1C CACNA1D SCN8A KCNMA1	2.51e-04	139	76	4	16985003
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNA1C CACNA1D	2.56e-04	11	76	2	18809727
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	CACNA1C CACNA1D MET KCNMA1	2.79e-04	143	76	4	20424473
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ACSL3 NF1 BRD4 CLTC USP24 CPSF1 EZH2 STRIP1	2.89e-04	774	76	8	15302935
Pubmed	Fibroblast-derived Hgf controls recruitment and expansion of muscle during morphogenesis of the mammalian diaphragm.	MET MYH2	3.07e-04	12	76	2	36154712
Pubmed	Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut.	TREH LAMP1	3.62e-04	13	76	2	36504079
Pubmed	ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells.	CLTC LAMP1	3.62e-04	13	76	2	29222402
Pubmed	Ambra1 deficiency impairs mitophagy in skeletal muscle.	MYH2 LAMP1	3.62e-04	13	76	2	35593053
Pubmed	The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.	MYH2 PRKCQ	3.62e-04	13	76	2	8948582
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	OR11L1 NCKAP1 DSG3 TREH EHD1 CLTC ABCB11 LAMP1 STRIP1	3.69e-04	1016	76	9	19056867
Pubmed	Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.	MET MYH2	4.22e-04	14	76	2	17881575
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA1D	4.86e-04	15	76	2	20188150
Pubmed	Divergent and conserved roles of Dll1 signaling in development of craniofacial and trunk muscle.	MET MYH2	4.86e-04	15	76	2	25220152
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA1D	4.86e-04	15	76	2	24453333
Interaction	INA interactions	KRT39 KLHL36 BRD4 TBCK KCNMA1 EZH2 RSPRY1	1.71e-06	173	67	7	int:INA
Interaction	SCN11A interactions	CACNA1C CACNA1D SCN8A	1.55e-05	15	67	3	int:SCN11A
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL11 CACNA1C CACNA1D FRYL ADAR	1.21e-05	174	76	5	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C NF1 STXBP5L SCN8A KCNMA1	1.31e-05	177	76	5	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1 ME1	1.35e-05	178	76	5	24e8c62060455159235985f456af0c5023a7f3f5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1 ME1	1.35e-05	178	76	5	4f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RGL1 CSF2RA AOAH KCNMA1 ME1	1.85e-05	190	76	5	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1 ME1	1.85e-05	190	76	5	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	RGL1 CSF2RA AOAH KCNMA1 ME1	1.99e-05	193	76	5	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	RGL1 CSF2RA AOAH KCNMA1 ME1	2.04e-05	194	76	5	f09675cd472200363c458952f00d2e41990800ee
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RGL1 CSF2RA AOAH KCNMA1 ME1	2.04e-05	194	76	5	663e7e7fe48157e808b4f1a0ea6ad41944e857a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1 ME1	2.04e-05	194	76	5	1dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1 ME1	2.04e-05	194	76	5	c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	RGL1 CSF2RA AOAH KCNMA1 ME1	2.09e-05	195	76	5	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OR52K1 CSF2RA KCNMA1 EZH2 ADAMTSL4	2.20e-05	197	76	5	d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D STXBP5L SCN8A KCNMA1	2.25e-05	198	76	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D STXBP5L SCN8A KCNMA1	2.25e-05	198	76	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D STXBP5L SCN8A KCNMA1	2.25e-05	198	76	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C MYH2 MYLK4 ABCB11	1.70e-04	162	76	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	RGL1 CSF2RA AOAH KCNMA1	1.86e-04	166	76	4	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 OR52K1 CSF2RA SACS	1.91e-04	167	76	4	1bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	1.95e-04	168	76	4	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	Sigmoid-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	CSF2RA AOAH KCNMA1 GPR160	1.95e-04	168	76	4	bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	1.95e-04	168	76	4	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	GPM6B MET TMEM179 PERM1	2.04e-04	170	76	4	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL3 MET RELN PRKCQ	2.18e-04	173	76	4	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GHR CACNA1C SACS KCNMA1	2.18e-04	173	76	4	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF2RA AOAH CLTC GPR160	2.28e-04	175	76	4	53e6f1f8dd482dfa2539e068dacefbb6e08443bc
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF2RA AOAH CLTC GPR160	2.33e-04	176	76	4	adb679e69c0c17f0caee4c141bac55d03c963012
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF2RA AOAH CLTC GPR160	2.38e-04	177	76	4	ab92ffc9624850a50c88e6b8f3a517ff2251ff15
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPM6B STK36 RELN TEX15	2.38e-04	177	76	4	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLTC TEX15 EZH2 ME1	2.38e-04	177	76	4	3081ce5fc66a1bb833719d6c0e0a6fc7115eeb91
ToppCell	Globus_pallidus-Macroglia\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ACSL3 GPM6B LAMP1 PRKCQ	2.49e-04	179	76	4	ab50f711b004b96107f813c9a2526ec21d1c8027
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 CSF2RA AOAH KCNMA1	2.54e-04	180	76	4	66c7b02d85e32ba3e7530d0c4aff17e7525ccdd8
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CSF2RA AOAH CLTC GPR160	2.54e-04	180	76	4	a600bc705993d3a010550a25d3b54358946f061f
ToppCell	droplet-Heart-4Chambers-21m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN NCKAP1 KLHL36 PRKCQ	2.82e-04	185	76	4	bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	2.94e-04	187	76	4	6ab51e17a7782c2ae6394cad813dc3a2cde70c89
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	GHR CACNA1C GPM6B CACNA1D	2.94e-04	187	76	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	2.94e-04	187	76	4	e176b5b051690f840f3b12c8f7c4cc10cbe2bbae
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C RGL1 USP24 KCNMA1	3.00e-04	188	76	4	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C RGL1 USP24 KCNMA1	3.00e-04	188	76	4	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C RGL1 USP24 KCNMA1	3.00e-04	188	76	4	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 CSF2RA AOAH KCNMA1	3.00e-04	188	76	4	fcf1bebef7aa81b4a11c1f9e4319339c290ecd22
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.00e-04	188	76	4	7499e353ea5853d06558b20cedee3c7910425d7d
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.00e-04	188	76	4	562f5984efdbbcb8f53ddcee033ccbf9eb678425
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GHR GPM6B RGL1 KCNMA1	3.06e-04	189	76	4	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D KCNMA1 ADAMTSL4	3.06e-04	189	76	4	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.12e-04	190	76	4	8ff8c586237cf15f930416710bcff45205fe6f70
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RGL1 CSF2RA KCNMA1 ME1	3.12e-04	190	76	4	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	Control-Myeloid-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	ACSL3 CSF2RA AOAH KCNMA1	3.12e-04	190	76	4	d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCell	PND10-Epithelial-Epithelial_Alveolar\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.12e-04	190	76	4	dc20d323cee2741e39fba597263d6418ae0eadaf
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.12e-04	190	76	4	ec1bd4929dc82bec2c983a31ece4e3aa82f3a2ab
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	RGL1 CSF2RA AOAH KCNMA1	3.18e-04	191	76	4	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	3.18e-04	191	76	4	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GHR GPM6B RGL1 KCNMA1	3.18e-04	191	76	4	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C GPM6B CACNA1D KCNMA1	3.18e-04	191	76	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	10x3'2.3-week_17-19-Hematopoietic-MK-early_MK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EFHC2 LAPTM4B PRKCQ TEX15	3.18e-04	191	76	4	3839bf57419d3ec3d4464277bb33301d2b7d701f
ToppCell	PND14-Epithelial-Epithelial_Alveolar\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.18e-04	191	76	4	5f8b3b2d38b37027901db9a1cccdbd1ff70f29de
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GHR GPM6B RGL1 KCNMA1	3.18e-04	191	76	4	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.18e-04	191	76	4	2f71f1fb6b5872d84860840b22e789a87ab14eec
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D KCNMA1 ADAMTSL4	3.18e-04	191	76	4	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.18e-04	191	76	4	4ab3056f9af2a6caed39f32288562f480811cd7b
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GHR CACNA1C GPM6B CACNA1D	3.18e-04	191	76	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.24e-04	192	76	4	7ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH ME1	3.24e-04	192	76	4	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	RGL1 CSF2RA AOAH KCNMA1	3.24e-04	192	76	4	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	OR52K1 CSF2RA AOAH OR52K2	3.24e-04	192	76	4	5ea1a8119012eb8bc3100b739a0430377a8ac534
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH ME1	3.24e-04	192	76	4	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.24e-04	192	76	4	f206c015f091234e2c86dfa66926e97b2ea99690
ToppCell	PND28-Epithelial-Epithelial_Alveolar\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.24e-04	192	76	4	69963e8dc6d6368243e61da133484eb23225625a
ToppCell	PND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MET CLTC TEX15 ME1	3.24e-04	192	76	4	bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell	control-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PSME4 AOAH PRKCQ ADAR	3.31e-04	193	76	4	89d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	RGL1 CSF2RA AOAH ME1	3.31e-04	193	76	4	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	Immune-interstitial_macrophage_(C1Q_positive)\|World / Lineage, Cell type, age group and donor	RGL1 CSF2RA AOAH ME1	3.31e-04	193	76	4	64d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1	3.31e-04	193	76	4	bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MICU3 STXBP5L TMEM179 SCN8A	3.31e-04	193	76	4	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH ME1	3.31e-04	193	76	4	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA AOAH KCNMA1	3.31e-04	193	76	4	374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GHR CACNA1C GPM6B CACNA1D	3.37e-04	194	76	4	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 CSF2RA AOAH KCNMA1	3.37e-04	194	76	4	7c7091de47359760003e910cfbe63db5c99410d6
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 CSF2RA AOAH ME1	3.37e-04	194	76	4	ad72be9f6871b334e1f477d868c15e7792fadea5
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D231\|Adult / Lineage, Cell type, age group and donor	RGL1 CSF2RA AOAH ME1	3.37e-04	194	76	4	800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	RGL1 CSF2RA AOAH KCNMA1	3.37e-04	194	76	4	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA KCNMA1 ME1	3.37e-04	194	76	4	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	STK36 RELN IPO9 TREH	3.44e-04	195	76	4	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	RGL1 CSF2RA AOAH KCNMA1	3.44e-04	195	76	4	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	10x5'v1-week_14-16-Hematopoietic-MK-early_MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	EFHC2 LAPTM4B PRKCQ TEX15	3.44e-04	195	76	4	9b4f217325afb2efb9c65f298ac87649cb1e1af9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 CSF2RA AOAH ME1	3.44e-04	195	76	4	c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RGL1 CSF2RA KCNMA1 ME1	3.44e-04	195	76	4	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	GHR CACNA1C GPM6B CACNA1D	3.44e-04	195	76	4	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	LA-08._Macrophage\|LA / Chamber and Cluster_Paper	RGL1 CSF2RA AOAH KCNMA1	3.44e-04	195	76	4	5e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	3.44e-04	195	76	4	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	3.44e-04	195	76	4	ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D RELN CLTC FRYL	3.44e-04	195	76	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	3.44e-04	195	76	4	09df40ff9b493170861b3f6e57a942a834655b5c
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D RELN CLTC FRYL	3.44e-04	195	76	4	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL1 CSF2RA KCNMA1 LAMP1	3.44e-04	195	76	4	5a7c74f96f213c504abd65e751800da7e03e47d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CSF2RA AOAH KCNMA1 ME1	3.44e-04	195	76	4	34a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCell	10x3'2.3-week_12-13-Hematopoietic-MK-early_MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EFHC2 LAPTM4B PRKCQ TEX15	3.51e-04	196	76	4	fc541e328aed28e84d5b3835169c60da0d64cddc
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C CACNA1D STXBP5L SCN8A	3.51e-04	196	76	4	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Control-Myeloid-Macrophage\|Control / Disease state, Lineage and Cell class	ACSL3 RGL1 CSF2RA KCNMA1	3.51e-04	196	76	4	e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell	COVID-19-lung-Macrophage_metabolically_active\|lung / Disease (COVID-19 only), tissue and cell type	RGL1 CSF2RA AOAH KCNMA1	3.51e-04	196	76	4	a753d76d764c181eecb0e17a794a2e7d0ff70136
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D	3.41e-05	4	71	2	DOID:0060173 (implicated_via_orthology)
Disease	Autistic Disorder	GHR CACNA1C MET RELN NF1 KCNMA1	4.00e-05	261	71	6	C0004352
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1D KCNMA1	9.00e-05	36	71	3	DOID:11723 (implicated_via_orthology)
Disease	pancreatic cancer (biomarker_via_orthology)	MET EZH2	1.19e-04	7	71	2	DOID:1793 (biomarker_via_orthology)
Disease	autistic disorder (is_implicated_in)	MET RELN NF1	1.43e-04	42	71	3	DOID:12849 (is_implicated_in)
Disease	Osteosarcoma	MET BRD4 EZH2	2.01e-04	47	71	3	C0029463
Disease	non-syndromic X-linked intellectual disability (implicated_via_orthology)	ACSL3 THADA	2.03e-04	9	71	2	DOID:0050776 (implicated_via_orthology)
Disease	resting heart rate	FMNL3 CACNA1C CACNA1D MET	4.67e-04	149	71	4	EFO_0004351
Disease	Alopecia, Male Pattern	BRD4 ZDHHC13	5.87e-04	15	71	2	C4083212
Disease	Androgenetic Alopecia	BRD4 ZDHHC13	5.87e-04	15	71	2	C0162311
Disease	Female pattern alopecia (disorder)	BRD4 ZDHHC13	5.87e-04	15	71	2	C0263477
Disease	Manic Disorder	CACNA1C CACNA1D RELN	6.79e-04	71	71	3	C0024713
Disease	Manic	CACNA1C CACNA1D RELN	8.92e-04	78	71	3	C0338831
Disease	Depression, Bipolar	CACNA1C CACNA1D RELN	9.26e-04	79	71	3	C0005587
Disease	Glioblastoma	MET NF1 BRD4	9.26e-04	79	71	3	C0017636
Disease	Pseudopelade	BRD4 ZDHHC13	9.51e-04	19	71	2	C0086873
Disease	Juvenile Myelomonocytic Leukemia	NF1 EZH2	9.51e-04	19	71	2	C0349639
Disease	Alopecia	BRD4 ZDHHC13	9.51e-04	19	71	2	C0002170
Disease	dilated cardiomyopathy	FMNL3 ZBTB17	1.05e-03	20	71	2	EFO_0000407
Disease	Giant Cell Glioblastoma	MET NF1 BRD4	1.11e-03	84	71	3	C0334588
Disease	squamous cell lung carcinoma, family history of lung cancer	GHR NF1 EZH2	1.14e-03	85	71	3	EFO_0000708, EFO_0006953
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	MET NF1	1.40e-03	23	71	2	C1708353
Disease	Adenocarcinoma of large intestine	MET TBCK PRKCQ	1.63e-03	96	71	3	C1319315
Disease	Involutional paraphrenia	CACNA1C RELN	1.65e-03	25	71	2	C1571983
Disease	Psychosis, Involutional	CACNA1C RELN	1.65e-03	25	71	2	C1571984
Disease	Cerebral Astrocytoma	MET NF1	1.65e-03	25	71	2	C0750935
Disease	Intracranial Astrocytoma	MET NF1	1.65e-03	25	71	2	C0750936
Disease	Involutional Depression	CACNA1C RELN	1.65e-03	25	71	2	C0011574
Disease	Pilocytic Astrocytoma	MET NF1	1.65e-03	25	71	2	C0334583
Disease	Astrocytoma	MET NF1	1.65e-03	25	71	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	MET NF1	1.65e-03	25	71	2	C0280783
Disease	Diffuse Astrocytoma	MET NF1	1.65e-03	25	71	2	C0280785
Disease	Grade I Astrocytoma	MET NF1	1.65e-03	25	71	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	MET NF1	1.65e-03	25	71	2	C0205768
Disease	Mixed oligoastrocytoma	MET NF1	1.65e-03	25	71	2	C0547065
Disease	Childhood Cerebral Astrocytoma	MET NF1	1.65e-03	25	71	2	C0338070
Disease	Gemistocytic astrocytoma	MET NF1	1.79e-03	26	71	2	C0334581
Disease	Protoplasmic astrocytoma	MET NF1	1.79e-03	26	71	2	C0334580
Disease	Fibrillary Astrocytoma	MET NF1	1.79e-03	26	71	2	C0334582
Disease	Anaplastic astrocytoma	MET NF1	1.93e-03	27	71	2	C0334579
Disease	Weight Gain	KCNMA1 EZH2 ME1	1.93e-03	102	71	3	C0043094
Disease	free androgen index	CACNA1D MET MYH2 THADA ADAR	2.09e-03	374	71	5	EFO_0007005

Protein segments in the cluster

Peptide	Gene	Start	Entry
CAAFNSQEFMGQLYQ	ADAMTSL4	391	Q6UY14
IQDFNTMFTNCYIYN	BRD4	126	O60885
CNDSAFFRGEIMFQY	ADGRG2	116	Q8IZP9
DRFDCQYLMATFVNV	CDS2	381	O95674
AFAQCIMFIANSASY	ABCB11	986	O95342
VFYAMNSQVNFDFIL	RGL1	716	Q9NZL6
DMTYAQLYSFLNCLQ	AOAH	441	P28039
MNFLDSYFSQKAFAC	DSG3	786	P32926
ECISQMYFFIFFTDL	OR1J2	96	Q8NGS2
RNLLAVCSDYFNSMF	KLHL36	61	Q8N4N3
CTFQTKENLFFVMEY	PRKCQ	446	Q04759
MNVVQCFAYFLQDFC	IL17RD	371	Q8NFM7
YGMNCLIQFEDFANV	ME1	236	P48163
CQNFYKDFTLQIDMA	KCNMA1	206	Q12791
YLMNNFNARFSLDDC	KRT39	71	Q6A163
FSMYCNFFNNSERNL	CPSF1	16	Q10570
NMFENFDTFIYSCVY	EFHC2	631	Q5JST6
QLNSDMNFFNQLAFC	EID3	106	Q8N140
MNFFNQLAFCDFLFL	EID3	111	Q8N140
YMCSFLFNLNNDFVV	EZH2	661	Q15910
YNHVAFNACLVQMFF	OR51I1	91	Q9H343
SYNACAVQMFFFVAL	OR5B2	91	Q96R09
AIFCIQYNIRSFMNV	MYH2	816	Q9UKX2
ASFQFMQECAQYFLE	FRYL	241	O94915
NTCYNSNQLEKMAFF	MYLK4	11	Q86YV6
FCYQIFDFALNMLVA	LAPTM4B	196	Q86VI4
LEDFAIALNMYNFAS	MICU3	436	Q86XE3
AISFSACMAQLYFFV	OR11L1	91	Q8NGX0
NICNTNEFYMSYHLF	GPM6B	211	Q13491
FYAERFQRFMCNTVF	PIP5K1A	436	Q99755
IFCFYSRAFEKMFQQ	NCKAP1	541	Q9Y2A7
DLNLTNAEFIQFYFM	RELN	2566	P78509
YFFENENVCMIFNAG	IFT172	401	Q9UG01
CQNFMEYFCISLAFV	GPR160	51	Q9UJ42
YCFFQMSVVNSNFYQ	KLHL11	546	Q9NVR0
FDNFAFAMLTVFQCI	CACNA1C	346	Q13936
YAQFASQTCEFNMIE	ADAR	511	P55265
VSLCQENFLMDNAYF	GHR	521	P10912
DYLSFAQCSVMFDFE	FMNL3	141	Q8IVF7
FLCQFAQQPCYIMFS	IPO9	1011	Q96P70
CIMANFSAAFSVNYD	LAMP1	41	P11279
MFQQFQASCLVLFFL	GPX6	1	P59796
NAFGNAFLNRFMCAQ	EHD1	126	Q9H4M9
ENDFEALLMYFNCNL	SACS	3381	Q9NZJ4
FAFSQNDMCLVFVAF	PERM1	726	Q5SV97
NFDNFAFAMLTVFQC	CACNA1D	346	Q01668
AQNFSCFIYNADLMN	CSF2RA	121	P15509
LDFQQYVFINQMCYH	LRRC8D	141	Q7L1W4
TFICNIFDYLRVNNM	MIF4GD	106	A9UHW6
AAQMFFCAVFATVEN	OR5B17	96	Q8NGF7
MYFFLANLSLTDACF	OR1N2	76	Q8NGR9
DQEINFFACLVQMFF	OR52K1	91	Q8NGK4
DREINFFACLAQMFF	OR52K2	91	Q8NGK3
AMCAFPIKYVNDFFN	MET	361	P08581
QQYKNFMSSICNSLF	THADA	726	Q6YHU6
ASFMSYQQCEFNFGA	RSPRY1	466	Q96DX4
QFEYMAQHLVFANCI	STRIP1	596	Q5VSL9
YNNCAAQLFFFIFMG	OR6C3	91	Q9NZP0
LMAVIQAYFACTFNL	STK36	531	Q9NRP7
FIADNFCMRGLSNFY	STXBP5L	701	Q9Y2K9
AQACFMYNFQLVTLY	ACSL3	176	O95573
DVFMEYNLIQQCTAF	CLTC	551	Q00610
LENYMNLASVDFFFC	ZNF562	71	Q6V9R5
YKFEEMFNENCFLVQ	ZNF460	171	Q14592
YNLGFMQNLADFFQC	ZDHHC13	576	Q8IUH4
MALNNFLFAQCACYF	TMEM179	1	Q6ZVK1
NFLLPQNQFAMFLYC	TMEM247	166	A6NEH6
QNQFAMFLYCFIFIH	TMEM247	171	A6NEH6
AFLCQAEELMSNFYS	TREH	351	O43280
YFTLFMNLLNDCSEV	NF1	1106	P21359
FNFETFGNSMICLFQ	SCN8A	1686	Q9UQD0
ILNCDYTNSMFDYFL	TRAV29DV5	46	P04437
LYLNFNNEALAYACM	TBCK	556	Q8TEA7
QTMVFYNLFIFLNNE	PSME4	1666	Q14997
AQALVMFQTDADFYQ	ZBTB17	741	Q13105
CAQYFFLFNTFVQKQ	USP24	2281	Q9UPU5
NAELTISFFLCQMLY	TEX15	2246	Q9BXT5
AQLDTFNYQSCFMQS	ZSWIM1	56	Q9BR11