Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserotonin-gated monoatomic cation channel activity

HTR3A HTR3E HTR3D

4.86e-075743GO:0022850
GeneOntologyMolecularFunctionserotonin receptor activity

HTR3A HTR3E HTR3D

9.69e-076743GO:0099589
GeneOntologyMolecularFunctionribosomal protein S6 kinase activity

RPS6KA2 RPS6KA3 RPS6KA6

1.69e-067743GO:0004711
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

HTR3A HTR3E HTR3D

5.42e-0443743GO:0005231
GeneOntologyMolecularFunctionglycosyltransferase activity

FUT11 ART3 DPY19L4 GYG2 UGGT2 B4GALT4

6.96e-04288746GO:0016757
GeneOntologyMolecularFunctiontransporter activity

SLC37A1 GJB3 PIEZO2 HTR3A SLC16A5 HTR3E DISP2 HTR3D ATP8B1 PANX2 MFSD4B PKDREJ XPR1

8.30e-0412897413GO:0005215
GeneOntologyMolecularFunctionUDP-glucosyltransferase activity

GYG2 UGGT2

1.03e-0313742GO:0035251
GeneOntologyMolecularFunctionhexosyltransferase activity

FUT11 DPY19L4 GYG2 UGGT2 B4GALT4

1.12e-03211745GO:0016758
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

HTR3A HTR3E HTR3D

1.24e-0357743GO:1904315
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC37A1 GJB3 PIEZO2 HTR3A SLC16A5 HTR3E DISP2 HTR3D PANX2 MFSD4B PKDREJ XPR1

1.25e-0311807412GO:0022857
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

HTR3A HTR3E HTR3D

1.44e-0360743GO:0099529
GeneOntologyMolecularFunctiontransmitter-gated channel activity

HTR3A HTR3E HTR3D

1.81e-0365743GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

HTR3A HTR3E HTR3D

1.81e-0365743GO:0022824
GeneOntologyMolecularFunctionmagnesium ion binding

RPS6KA2 RPS6KA3 RPS6KA6 SIK2 ATP8B1

2.24e-03247745GO:0000287
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

HTR3A HTR3E HTR3D

2.72e-0375743GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

HTR3A HTR3E HTR3D

2.94e-0377743GO:0005230
GeneOntologyMolecularFunctionglucosyltransferase activity

GYG2 UGGT2

2.98e-0322742GO:0046527
GeneOntologyMolecularFunctionchannel activity

GJB3 PIEZO2 HTR3A HTR3E HTR3D PANX2 PKDREJ

3.29e-03525747GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GJB3 PIEZO2 HTR3A HTR3E HTR3D PANX2 PKDREJ

3.32e-03526747GO:0022803
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC37A1 XPR1

3.55e-0324742GO:0005315
GeneOntologyMolecularFunctiongap junction channel activity

GJB3 PANX2

3.85e-0325742GO:0005243
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R1 TAS2R50

4.48e-0327742GO:0033038
GeneOntologyBiologicalProcessserotonin receptor signaling pathway

HTR3A HTR3E HTR3D

6.32e-0611713GO:0007210
GeneOntologyCellularComponentserotonin receptor complex

HTR3A HTR3E HTR3D

3.90e-075723GO:0098665
GeneOntologyCellularComponentserotonin-activated cation-selective channel complex

HTR3A HTR3E HTR3D

3.90e-075723GO:1904602
GeneOntologyCellularComponent90S preribosome

WDR36 PES1 NOC4L

1.34e-0429723GO:0030686
GeneOntologyCellularComponentneurotransmitter receptor complex

HTR3A HTR3E HTR3D

6.84e-0450723GO:0098878
DomainRibosomal_S6_kinase_II

RPS6KA2 RPS6KA3 RPS6KA6

1.18e-066743IPR016239
Domain-

HTR3A HTR3E HTR3D

9.99e-05237431.20.120.370
DomainAcetylcholine_rcpt_TM

HTR3A HTR3E HTR3D

9.99e-0523743IPR027361
DomainPkinase_C

RPS6KA2 RPS6KA3 RPS6KA6

4.21e-0437743IPR017892
DomainPkinase_C

RPS6KA2 RPS6KA3 RPS6KA6

6.13e-0442743PF00433
DomainGlyco_transf_8

GYG2 UGGT2

6.83e-0410742PF01501
DomainGlyco_trans_8

GYG2 UGGT2

6.83e-0410742IPR002495
DomainNeur_chan_memb

HTR3A HTR3E HTR3D

8.02e-0446743PF02932
DomainNeur_chan_LBD

HTR3A HTR3E HTR3D

8.54e-0447743PF02931
DomainNEUROTR_ION_CHANNEL

HTR3A HTR3E HTR3D

8.54e-0447743PS00236
DomainNeurotrans-gated_channel_TM

HTR3A HTR3E HTR3D

8.54e-0447743IPR006029
Domain-

HTR3A HTR3E HTR3D

8.54e-04477432.70.170.10
DomainNeur_channel

HTR3A HTR3E HTR3D

8.54e-0447743IPR006201
DomainNeur_chan_lig-bd

HTR3A HTR3E HTR3D

8.54e-0447743IPR006202
DomainAGC-kinase_C

RPS6KA2 RPS6KA3 RPS6KA6

1.42e-0356743IPR000961
DomainAGC_KINASE_CTER

RPS6KA2 RPS6KA3 RPS6KA6

1.42e-0356743PS51285
DomainS_TK_X

RPS6KA2 RPS6KA3 RPS6KA6

1.42e-0356743SM00133
DomainApc4_WD40_dom

NWD1 WDR36

2.81e-0320742IPR024977
DomainANAPC4_WD40

NWD1 WDR36

2.81e-0320742PF12894
DomainMFS_1

SLC37A1 SLC16A5 MFSD4B

3.54e-0377743PF07690
DomainMFS

SLC37A1 SLC16A5 MFSD4B

3.54e-0377743IPR011701
Domain-

GYG2 UGGT2 B4GALT4

4.08e-03817433.90.550.10
DomainTAS2R

TAS2R1 TAS2R50

4.73e-0326742PF05296
DomainT2R

TAS2R1 TAS2R50

4.73e-0326742IPR007960
DomainNucleotide-diphossugar_trans

GYG2 UGGT2 B4GALT4

5.15e-0388743IPR029044
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

RPS6KA2 RPS6KA3 RPS6KA6

5.59e-075553MM15108
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

RPS6KA2 RPS6KA3 RPS6KA6

1.11e-066553M47936
PathwayREACTOME_RSK_ACTIVATION

RPS6KA2 RPS6KA3 RPS6KA6

1.95e-067553M27369
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

RPS6KA2 RPS6KA3 RPS6KA6

2.47e-0515553MM15103
PathwayREACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION

HTR3A RPS6KA2 RPS6KA3 HTR3E RPS6KA6 HTR3D

1.41e-04205556M752
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

RPS6KA2 RPS6KA3 RPS6KA6

1.72e-0428553M837
PathwayREACTOME_CREB_PHOSPHORYLATION

RPS6KA2 RPS6KA3

3.10e-047552M27096
PathwayREACTOME_CREB_PHOSPHORYLATION

RPS6KA2 RPS6KA3

3.10e-047552MM14784
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

RPS6KA2 RPS6KA3 RPS6KA6

3.37e-0435553MM15109
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

RPS6KA2 RPS6KA3 BCR

3.66e-0436553M1315
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

HTR3A RPS6KA2 RPS6KA3 HTR3E RPS6KA6 HTR3D

6.16e-04270556M15514
PathwayWP_THERMOGENESIS

RPS6KA2 RPS6KA3 RPS6KA6 CPT1B

8.23e-04108554M39746
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

RPS6KA2 RPS6KA3 RPS6KA6

9.12e-0449553M891
PathwayREACTOME_NEURONAL_SYSTEM

HTR3A RPS6KA2 RPS6KA3 HTR3E RPS6KA6 HTR3D PANX2

1.03e-03411557M735
PathwayKEGG_MTOR_SIGNALING_PATHWAY

RPS6KA2 RPS6KA3 RPS6KA6

1.08e-0352553M7561
PathwayREACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK

RPS6KA2 RPS6KA3

1.73e-0316552MM15477
Pubmed

Polymorphism in HTR3D shows different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy.

HTR3A HTR3E HTR3D

3.69e-08474320602613
Pubmed

A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patients.

HTR3A HTR3E HTR3D

9.22e-08574320356718
Pubmed

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.

RPS6KA2 RPS6KA3 RPS6KA6

9.22e-08574337068088
Pubmed

Characterization of the novel human serotonin receptor subunits 5-HT3C,5-HT3D, and 5-HT3E.

HTR3A HTR3E HTR3D

9.22e-08574317392525
Pubmed

RSK2 is a modulator of craniofacial development.

RPS6KA2 RPS6KA3 RPS6KA6

9.22e-08574324416220
Pubmed

Influence of 5-HT3 receptor subunit genes HTR3A, HTR3B, HTR3C, HTR3D and HTR3E on treatment response to antipsychotics in schizophrenia.

HTR3A HTR3E HTR3D

9.22e-08574319794330
Pubmed

Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation.

RPS6KA2 RPS6KA3 RPS6KA6

9.22e-08574311160957
Pubmed

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

RPS6KA2 RPS6KA3 RPS6KA6

1.84e-07674312832467
Pubmed

Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy.

HTR3A HTR3E HTR3D

1.84e-07674320021265
Pubmed

RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.

RPS6KA2 RPS6KA6

4.47e-06274223635776
Pubmed

MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit.

RPS6KA2 RPS6KA3

4.47e-06274211495723
Pubmed

RIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A) receptors despite direct interactions with 5-HT3A, -C, -D, and -E subunits.

HTR3A HTR3E

1.34e-05374220522555
Pubmed

Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning.

RPS6KA2 RPS6KA3

1.34e-05374212393804
Pubmed

Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.

HTR3E HTR3D

1.34e-05374221192076
Pubmed

Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinase.

RPS6KA2 RPS6KA3

1.34e-05374212016217
Pubmed

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome.

HTR3A HTR3E

1.34e-05374218614545
Pubmed

Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.

HTR3E HTR3D

1.34e-05374212801637
Pubmed

Human rsk isoforms: cloning and characterization of tissue-specific expression.

RPS6KA2 RPS6KA3

1.34e-0537428141249
Pubmed

The Clinical Implications of RSK1-3 in Human Breast Cancer.

RPS6KA2 RPS6KA3

1.34e-05374226977024
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

INF2 EFHD1 RPS6KA2 RPS6KA3 RPS6KA6

2.41e-0516074531678930
Pubmed

Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene.

RPS6KA2 RPS6KA3

2.67e-0547429770464
Pubmed

A cluster of novel serotonin receptor 3-like genes on human chromosome 3.

HTR3E HTR3D

2.67e-05474214597179
Pubmed

p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.

RPS6KA2 RPS6KA3

2.67e-05474221527514
Pubmed

RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation.

RPS6KA2 RPS6KA3

2.67e-0547427623830
Pubmed

Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis.

RPS6KA3 RPS6KA6

2.67e-05474212711546
Pubmed

90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

RPS6KA2 RPS6KA3

4.45e-05574210480933
Pubmed

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes.

RPS6KA2 RPS6KA3

4.45e-05574215526037
Pubmed

The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction.

RPS6KA2 RPS6KA3

4.45e-05574215867353
Pubmed

Ribosomal S6 kinase 2 interacts with and phosphorylates PDZ domain-containing proteins and regulates AMPA receptor transmission.

RPS6KA2 RPS6KA3

4.45e-05574216217014
Pubmed

Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo.

RPS6KA2 RPS6KA3

4.45e-0557429915826
Pubmed

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase.

RPS6KA2 RPS6KA3

6.66e-0567428688081
Pubmed

NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation.

RPS6KA2 RPS6KA3

6.66e-05674211175347
Pubmed

The MAP kinase ERK5 binds to and phosphorylates p90 RSK.

RPS6KA2 RPS6KA3

6.66e-05674216626623
Pubmed

Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinases.

RPS6KA2 RPS6KA3

6.66e-0567428939914
Pubmed

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.

USP38 ASB11 RNFT1

8.63e-054074330759391
Pubmed

The small-subunit processome is a ribosome assembly intermediate.

WDR36 NOC4L

1.24e-04874215590835
Pubmed

CREB is a regulatory target for the protein kinase Akt/PKB.

RPS6KA2 RPS6KA3

1.24e-0487429829964
Pubmed

P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons.

RPS6KA2 RPS6KA3

1.59e-04974219555761
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PDS5B DNAAF5 FADS1 ADAMTS1 INF2 PES1 UGGT2 YIPF3 KIAA2013

1.73e-0494274931073040
Pubmed

A candidate gene study of obstructive sleep apnea in European Americans and African Americans.

HTR3A HTR3E HTR3D

1.90e-045274320538960
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

PLEKHG4B USP38 MFSD4B

3.35e-046374311572484
Pubmed

Entire mitogen activated protein kinase (MAPK) pathway is present in preimplantation mouse embryos.

RPS6KA2 RPS6KA3

4.00e-041474215305288
Pubmed

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

RPS6KA2 RPS6KA3

4.00e-04147429687510
Pubmed

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

FADS1 EFHD1 ATP8B1

4.20e-046874322001757
Pubmed

Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.

FADS1 CCDC190 SCUBE3 MYO16

4.44e-0416674419906978
Pubmed

The DNA sequence of human chromosome 22.

TBC1D22A PES1 PANX2 CPT1B PKDREJ

4.58e-0430074510591208
Pubmed

Mutation of the 3-Phosphoinositide-Dependent Protein Kinase 1 (PDK1) Substrate-Docking Site in the Developing Brain Causes Microcephaly with Abnormal Brain Morphogenesis Independently of Akt, Leading to Impaired Cognition and Disruptive Behaviors.

RPS6KA2 RPS6KA3

4.61e-041574227644329
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

WDR36 ADAMTS1 HECW2 BCR KIAA2013

5.54e-0431374538270169
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

WDR36 INF2 PES1 NOC4L DHX57

7.23e-0433274525693804
Pubmed

A mega-analysis of genome-wide association studies for major depressive disorder.

HTR3E HTR3D

7.46e-041974222472876
Pubmed

Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules.

RPS6KA2 RPS6KA3

8.28e-042074221421818
Pubmed

A novel family of mammalian taste receptors.

TAS2R1 TAS2R50

9.14e-042174210761934
Pubmed

Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

TAS2R1 TAS2R50

1.00e-032274212734386
Pubmed

The molecular receptive ranges of human TAS2R bitter taste receptors.

TAS2R1 TAS2R50

1.10e-032374220022913
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PLEKHG4B SLC37A1 DNAAF5 CDS1 INF2 TBC1D22A EFHD1 RPS6KA2 ATP8B1 BCR

1.19e-031489741028611215
Pubmed

Receptors for bitter and sweet taste.

TAS2R1 TAS2R50

1.30e-032574212139982
Pubmed

Molecular mechanisms of bitter and sweet taste transduction.

TAS2R1 TAS2R50

1.40e-032674211696554
Pubmed

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.

USP38 MYO16

1.51e-032774234709416
Pubmed

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.

TAS2R1 TAS2R50

1.51e-032774212581520
Pubmed

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.

EBF2 LINGO2

1.63e-032874224427155
Pubmed

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.

TAS2R1 TAS2R50

1.63e-032874215744053
Pubmed

Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions.

GJB3 ATP8B1

1.75e-032974224952082
Pubmed

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.

TAS2R1 TAS2R50

1.87e-033074212679530
Pubmed

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

SACS RPS6KA2

2.13e-033274225189868
InteractionCMKLR1 interactions

PDS5B DNAAF5 FADS1 YIPF3 KIAA2013 XPR1

1.27e-06101696int:CMKLR1
Cytoband3q27.1

HTR3E HTR3D

8.76e-04277423q27.1
Cytoband11q23.1

HTR3A SIK2

1.65e-033774211q23.1
Cytoband22q13.33

PANX2 CPT1B

1.74e-033874222q13.33
CytobandEnsembl 112 genes in cytogenetic band chr22q13

TBC1D22A PANX2 CPT1B PKDREJ

2.03e-03330744chr22q13
GeneFamily5-hydroxytryptamine receptors, ionotropic

HTR3A HTR3E HTR3D

1.44e-075453172
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA2 RPS6KA3 RPS6KA6

2.34e-06114531156
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

HECW2 BCR

3.62e-0336452823
GeneFamilyTaste 2 receptors

TAS2R1 TAS2R50

4.23e-03394521162
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 ART3 SACS HECW2 LINGO2

1.00e-05172745073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellCerebellum-Macroglia|Cerebellum / BrainAtlas - Mouse McCarroll V32

NWD1 TMEM229A EFHD1 CCDC190 ITIH3

1.39e-0518474591b047a01d2cad231308279ca37fa699630f7864
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCAIM SLC16A5 ADAMTS1 EFHD1 SCTR

1.62e-05190745bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCAIM SLC16A5 ADAMTS1 EFHD1 SCTR

1.62e-05190745b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 ART3 ADAMTS1 HECW2 B4GALT4

1.75e-051937455d42979d811ee13a07dee08a3743a90776017cb4
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 ART3 ADAMTS1 HECW2 B4GALT4

1.75e-0519374597c0730aad9135ac681250b3871cc094a28f80a7
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

FMO2 ADAMTS1 EFHD1 SCUBE3 ITIH3

1.93e-0519774578d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FMO2 ADAMTS1 EFHD1 SCUBE3 ITIH3

1.93e-0519774531bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

EBF2 ART3 ADAMTS1 EFHD1 DISP2

2.02e-0519974545c3b853900d8c3d5965117d904e3714100138bc
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L EBF2 TMEM229A RPS6KA3

6.95e-051327444152529611eeacf0c547e2a134d5b98c45426b13
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GREB1L EBF2 GJB3 RPS6KA2

6.95e-05132744ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

EBF2 FMO2 PIEZO2 HECW2

1.26e-04154744511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellClub_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

GREB1L GJB3 FMO2 SCUBE3

1.46e-04160744b261a3a49c850d92bc9e04fc3527c752dfe37a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NWD1 TCAIM EFHD1 SCTR

1.46e-0416074403b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

1.50e-04161744fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLEKHG4B FMO2 EFHD1 ATP8B1

1.50e-041617442d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

1.50e-04161744c53c461fc721a7960cef86662f49e2a495520701
ToppCellClub_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

FMO2 EFHD1 SCUBE3 ATP8B1

1.50e-04161744342f5c61d37df61b35c18f5d258043a8f5cef629
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC37A1 CDS1 SIK2 MCMDC2

1.53e-041627448e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB3 FMO2 ADAMTS1 SCTR

1.53e-041627443a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

1.53e-041627442ac02523348660e514d464f8f2434ee0c312d784
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJB3 FMO2 ADAMTS1 SCTR

1.53e-0416274404b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC37A1 CDS1 SIK2 MCMDC2

1.53e-04162744e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCellClub_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

GJB3 FMO2 EFHD1 PANX2

1.61e-041647444e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ASB11 HECW2 RPS6KA2 DIPK2B

1.61e-041647448f074940afdbda88a4b697a7ddc687e09a4b818b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ASB11 HECW2 RPS6KA2 DIPK2B

1.61e-04164744a784f47f67a5eda84d58ad7d9400e3978edbb487
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ASB11 HECW2 RPS6KA2 DIPK2B

1.61e-041647441a1795969673232191425dde84ab24ee6a98143f
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

SLC35G3 SCUBE3 PANX2 B4GALT4

1.61e-0416474481c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCellClub_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

GJB3 FMO2 SCUBE3 CYP4X1

1.68e-04166744a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST1 HECW2 BCR ITIH3

1.84e-0417074467d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST1 HECW2 BCR ITIH3

1.84e-041707448e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DNAAF5 NDST1 SLC16A5 ASB11

1.93e-04172744df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EBF2 TMEM87B SCUBE3 MTBP

1.97e-04173744b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NDST1 CDS1 FMO2 MCMDC2

2.01e-04174744e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

NDST1 CDS1 FMO2 MCMDC2

2.10e-04176744bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EBF2 EFHD1 CYP4X1 ZP2

2.10e-041767448b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.15e-04177744c274fbdc141855ff4581d437d4997c64cc193278
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.15e-04177744c8a51e480b978dc0ded85583261f2c892e085be8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.15e-04177744f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCelldroplet-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 ART3 SACS PKDREJ

2.24e-04179744dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 ADAMTS1 HECW2 DIPK2B

2.34e-04181744e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 ADAMTS1 EFHD1 ITIH3

2.39e-041827441c1a687f728341c209b048b6715bcddd0ac20069
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.39e-0418274441b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.39e-041827445e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.39e-04182744b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EBF2 ADAMTS1 EFHD1 ITIH3

2.39e-0418274497bb07478f56a937b490fba121ee603db64134a1
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

PLEKHG4B EFHD1 CYP4X1 ATP8B1

2.44e-04183744940cbe298e9c53b5622af09264586ed823d3141f
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

EBF2 ADAMTS1 EFHD1 ATP8B1

2.60e-04186744e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 CDS1 USP38 TMEM87B

2.65e-0418774443ef900b76f3c38bd8ce9858201124130c743d56
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TMEM229A ADAMTS1 EFHD1

2.65e-041877449aa411ae9b5a923378a5daebb8bb2fc2613f2510
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 CDS1 USP38 TMEM87B

2.65e-041877446e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

NDST1 FMO2 INF2 MYO16

2.65e-041877443a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

PIEZO2 ADAMTS1 HECW2 DIPK2B

2.65e-041877441e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TMEM229A ADAMTS1 EFHD1

2.70e-04188744842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TMEM229A ADAMTS1 EFHD1

2.70e-04188744a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR3A SLC16A5 ASB11 EFHD1

2.70e-04188744ab6fa1beff91584d9303c2a33735de89aae8d5cd
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EBF2 ADAMTS1 EFHD1 CYP4X1

2.76e-041897441ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell5'-Adult-Appendix-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 EFHD1 CYP4X1 ITIH3

2.76e-04189744b6bb4327b4560d07d2b728abcc5f144f428948a5
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS1 EFHD1 SCTR ITIH3

2.76e-04189744975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell5'-Adult-Appendix-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 EFHD1 CYP4X1 ITIH3

2.76e-041897440daa8efac08dca9525d2b8d421952068cab4eb50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.81e-04190744876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 FMO2 EFHD1 UGGT2

2.81e-0419074412992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellwk_08-11-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RPS6KA2 ZP2 ITIH3 DIPK2B

2.81e-04190744279c5f68b993dc7adbf9aa69fffb1321cdebc48a
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A5 EFHD1 RPS6KA6 CPT1B

2.81e-0419074468ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.81e-04190744be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS1 EFHD1 SCTR ITIH3

2.81e-0419074473d94fbae92029745989a8712eed8b99fd84c193
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 HECW2 RPS6KA2 DIPK2B

2.81e-0419074409a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO2 EFHD1 CYP4X1 SCTR

2.81e-04190744136ca6da77a202874376af193a1dd71d810c76c4
ToppCellwk_08-11-Endothelial-Lymph_endothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RPS6KA2 ZP2 ITIH3 DIPK2B

2.81e-04190744d7f1dc032d161529559e01832d1a3112c6f6cc1a
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A5 EFHD1 RPS6KA6 CPT1B

2.81e-04190744010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCellwk_20-22-Endothelial-Lymph_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RPS6KA2 ZP2 ITIH3 DIPK2B

2.87e-04191744631f95fd80dd3678b5b2ef201abf7fe646049af6
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EBF2 FMO2 CYP4X1 UGGT2

2.87e-0419174470c067c54084bfb02c29bab085f4defd477194fb
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIEZO2 FADS1 ADAMTS1 MYO16

2.93e-04192744162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART3 ADAMTS1 SCTR BCR

2.93e-04192744a804cb101c3a5585f72217e1143584b1ca436724
ToppCelldroplet-Lung-nan-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 HECW2 ATP8B1 B4GALT4

2.93e-0419274445929c757d873fe314cc36d27abd265414635490
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 HECW2 B4GALT4 DIPK2B

2.93e-041927445012cc3ec0766f06af447463413422b484446c43
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-Pericytes|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO2 EFHD1 CYP4X1 SCTR

2.93e-041927447aadc7c5bd03274f9861dde2febda5c37f8afc9c
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

EBF2 FMO2 CYP4X1 UGGT2

2.93e-04192744356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCelldroplet-Lung-nan-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS1 HECW2 ATP8B1 B4GALT4

2.93e-04192744beb336d3479821bdab7e8e2c58812f155e44e9a2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FMO2 PIEZO2 HECW2 DIPK2B

2.93e-04192744c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ART3 ADAMTS1 SCTR BCR

2.99e-04193744d0dcc0c11ccf99ff6b07e456d25b9742649aadd8
ToppCelldroplet-Pancreas-Endocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART3 ADAMTS1 HECW2 B4GALT4

2.99e-0419374495e64b9580d30c28702639a043a8b72ce1cadeb6
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS1 EFHD1 SCUBE3 ITIH3

2.99e-041937445182284dfa7c94027e94172e08f78c86b95d63f4
ToppCell368C-Fibroblasts-Fibroblast-K_(Pericytes)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS1 EFHD1 SCUBE3 ITIH3

2.99e-041937444f7bab0115469c855160636d168bd6e5d4e2dd2f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FMO2 PIEZO2 HECW2 DIPK2B

2.99e-0419374452e918884877b6659cdca0496390e440f73694a9
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RPS6KA2 ZP2 ITIH3 DIPK2B

3.05e-04194744bc03d0f8dca9f4ba10db2f2274293f8b119e8951
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RPS6KA2 ZP2 ITIH3 DIPK2B

3.05e-04194744640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ART3 ADAMTS1 EFHD1 ITIH3

3.11e-041957447155cc12cc6a97efd626bbdb95249fb3d7041dcf
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ART3 ADAMTS1 EFHD1 ITIH3

3.11e-04195744a52ee3ad6cd317f10b9308450517861ef2e363bb
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB11 RPS6KA2 DISP2 ATP8B1

3.11e-04195744bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCelltumor_Lung-Fibroblasts-Smooth_muscle_cells|tumor_Lung / Location, Cell class and cell subclass

FMO2 ADAMTS1 EFHD1 ITIH3

3.11e-04195744ea9ff25020c2fcd1bab80e1829af0f4e4777de8b
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ART3 ADAMTS1 EFHD1 ITIH3

3.11e-04195744b3660779f274ca97dd844cf83f62d85ba88cb182
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|367C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS1 EFHD1 SCUBE3 ITIH3

3.17e-04196744c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS1 EFHD1 SCUBE3 ITIH3

3.17e-041967442f76f050083483f0880639e6c34ff349caac3503
ToppCellLAM-Mesenchyme|LAM / Condition, Lineage and Cell class

FMO2 ADAMTS1 EFHD1 ITIH3

3.17e-04196744e7918b0cd5eeb675012f871f43f4388471845035
ToppCellILEUM-non-inflamed-(8)_Pericytes|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FMO2 ADAMTS1 EFHD1 CYP4X1

3.17e-04196744b98fe1519e420d8b03c66e164bf4544f3dbb2e44
ToppCellPericytes|World / shred by cell class for parenchyma

ADAMTS1 EFHD1 SCUBE3 ITIH3

3.17e-041967448e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell(5)_Fibroblast-K_(Pericytes)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ADAMTS1 EFHD1 SCUBE3 ITIH3

3.17e-04196744e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

FUT11 ADAMTS1 HECW2 DIPK2B

3.17e-0419674414dd6956ef420b660be0baf52a66960e57d75d16
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

FUT11 ADAMTS1 HECW2 DIPK2B

3.17e-041967442b777a2026b56839112fd179f2db482c49f4594a
ComputationalNeighborhood of PPP2R5B

SLC16A5 TBC1D22A ATP8B1 ZP2 ITIH3

1.68e-04173335MORF_PPP2R5B
ComputationalNeighborhood of ARL3

HTR3A SLC16A5 TBC1D22A ATP8B1 ZP2 ITIH3

2.83e-04304336MORF_ARL3
ComputationalNeighborhood of ERCC4

HTR3A SLC16A5 TBC1D22A ATP8B1 ZP2 ITIH3

3.79e-04321336MORF_ERCC4
ComputationalNeighborhood of TFDP2

SLC16A5 TBC1D22A ATP8B1 ZP2 ITIH3

6.25e-04230335MORF_TFDP2
ComputationalNeighborhood of IL13

HTR3A SLC16A5 TBC1D22A ZP2 ITIH3

6.76e-04234335MORF_IL13
ComputationalNeighborhood of BRCA1

SLC16A5 TBC1D22A ATP8B1 ZP2 ITIH3

1.14e-03263335MORF_BRCA1
ComputationalNeighborhood of MYL3

HTR3A ZP2 ITIH3

1.25e-0370333MORF_MYL3
ComputationalNeighborhood of FOSL1

HTR3A SLC16A5 TBC1D22A ATP8B1 ZP2 ITIH3

1.30e-03406336MORF_FOSL1
ComputationalNeighborhood of NOS2A

HTR3A SLC16A5 TBC1D22A ATP8B1 ITIH3

1.71e-03288335MORF_NOS2A
DrugBI D1870

RPS6KA2 RPS6KA3 RPS6KA6

5.34e-0611743ctd:C516541
Drugtridecyl-stigmatellin

CDS1 HTR3A HTR3E HTR3D

8.60e-0640744CID000448047
Drugacid violet

CDS1 RBL2

1.04e-052742CID000015537
DrugOvta

RPS6KA2 RPS6KA3 RPS6KA6

1.17e-0514743CID003081047
DrugAD 288

RPS6KA2 RPS6KA3 RPS6KA6

1.17e-0514743CID000073553
DrugR165481

RPS6KA2 RPS6KA3 RPS6KA6

1.79e-0516743CID005459348
Drugbenzoctamine

HTR3A HTR3E HTR3D

2.60e-0518743CID000028425
DrugDEAC

RPS6KA2 RPS6KA3 PES1 RPS6KA6

3.09e-0555744CID000007277
Drug8-OH-DPAT

HTR3A ART3 EFHD1 HTR3E HTR3D

3.99e-05117745CID000001220
DrugLumicolchicine gamma [6901-14-0]; Down 200; 10uM; MCF7; HT_HG-U133A

NDST1 INF2 RPS6KA2 RNFT1 ATP8B1 CPT1B

4.17e-051957463254_DN
DrugChelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A

MOCS3 TBC1D22A RPS6KA2 RNFT1 DHX57 ATP8B1

4.29e-051967466236_DN
DrugAsiaticoside [16830-15-2]; Up 200; 4.2uM; PC3; HT_HG-U133A

GREB1L NDST1 MOCS3 RNFT1 CPT1B BCR

4.42e-051977467244_UP
Drugritanserin

HTR3A EFHD1 HTR3E HTR3D

4.66e-0561744CID000005074
Drugazathioprine, USP; Down 200; 100uM; MCF7; HG-U133A

CDS1 GJB3 HTR3A RNFT1 GYG2 ATP8B1

4.81e-05200746338_DN
DrugAC1L1HE1

HTR3A EFHD1 HTR3E HTR3D

6.75e-0567744CID000004090
Drugpizotifen

HTR3A HTR3E HTR3D

7.20e-0525743CID000027400
Drugnaratriptan

HTR3A HTR3E HTR3D

7.20e-0525743CID000004440
Drug1-(1-naphthyl)piperazine

HTR3A HTR3E XPR1

8.12e-0526743CID000001342
DrugTubocurarine,d

HTR3A RPS6KA2 RPS6KA3 CPT1B

8.95e-0572744CID000001210
DrugAC1MS9WM

RPS6KA2 RPS6KA3 RPS6KA6

9.11e-0527743CID003530978
DrugK00085

RPS6KA2 RPS6KA3 RPS6KA6

9.11e-0527743CID009549283
DrugNSC169490

HTR3A HTR3E HTR3D

9.11e-0527743CID004210613
DrugNSC407316

HTR3A HTR3E HTR3D

1.02e-0428743CID000003067
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA2 RPS6KA3 RPS6KA6

4.89e-084693DOID:3783 (implicated_via_orthology)
Disease1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement

GREB1L FADS1

3.50e-0412692EFO_0800453
DiseaseMyoinositol measurement

TBC1D22A ZP2

3.50e-0412692EFO_0021652
Diseaselevel of Phosphatidylcholine (16:1_18:1) in blood serum

GREB1L FADS1

4.13e-0413692OBA_2045082
Disease4-acetamidobutanoate measurement

TBC1D22A PANX2

6.33e-0416692EFO_0021003
DiseaseAlzheimer disease, brain volume measurement

PDS5B LINGO2

7.16e-0417692EFO_0006930, MONDO_0004975
Diseaseairway responsiveness measurement

SCUBE3 LINGO2

1.44e-0324692EFO_0006897
Diseasexanthosine measurement

FMO2 LINGO2

1.56e-0325692EFO_0010549
Diseaseasthma

PLEKHG4B PDS5B FUT11 FADS1 WDR36 SIK2 SCUBE3

1.85e-03751697MONDO_0004979
Diseasebipolar I disorder

FADS1 RPS6KA2 MYO16

4.45e-03141693EFO_0009963

Protein segments in the cluster

PeptideGeneStartEntry
LQFLIRYHRFISFAL

CDS1

176

Q92903
FHRKRFSFYLLLGFL

HTR3E

6

A5X5Y0
TFHLSYKFRLLLLLT

B4GALT4

6

O60513
LLTFLFLLDHLKRVA

BCR

1176

P11274
KLLFHIYLLAVLAYS

HTR3A

451

P46098
LRKSNFFHFVLALYD

EBF2

61

Q9HAK2
LLIKVFLALLTHFYI

ASB11

26

Q8WXH4
HFTDRDKLRLLYTLA

DIPK2B

201

Q9H7Y0
SAIYQLLHFLLDRDF

DISP2

406

A7MBM2
FKRAANLYFLALLIL

ATP8B1

116

O43520
LLFNYKRFFVSLLHG

ATP8B1

1026

O43520
SLLYTELLARLHFFA

NWD1

806

Q149M9
YLNLALHLASDFFLK

PDS5B

56

Q9NTI5
YLLTLFSVAARLYKH

ADAMTS1

281

Q9UHI8
LKALLKHFDLFVRFL

MSL3P1

401

P0C860
LSLFFRKVYHLAAVR

RBL2

836

Q08999
LALIHQYLLDAFFTR

HECW2

1316

Q9P2P5
RYTAKHSSLFFLLFL

OR10S1

31

Q8NGN2
ALKYLVFLSEAHARL

MCMDC2

586

Q4G0Z9
FRDLLAKSLYSRLFS

MYO16

736

Q9Y6X6
KFYLAELALALDHLH

RPS6KA3

171

P51812
FLELLSKARNAHYLR

CCDC190

246

Q86UF4
DRLGLYTFKHLVRFL

NDST1

536

P52848
FLAFKHLVYLTHLNL

LINGO2

266

Q7L985
KFYLAELALALDHLH

RPS6KA6

176

Q9UK32
SKHAALLYTVTFLLF

OR2T34

26

Q8NGX1
SKHAALLYTVTFLLF

OR2T3

26

Q8NH03
ARFLIKELSYHNLEL

GREB1L

1581

Q9C091
AKLASADHFYLLLLA

INF2

696

Q27J81
FRRAKYHNALLCLLF

MFSD4B

221

Q5TF39
LIDSADYIHLAFLKR

GYG2

96

O15488
ILTFLLYASFHLSRK

SLC37A1

26

P57057
ELLAFLSRYKFHLAL

FUT11

266

Q495W5
KYHALYISALRKLFD

DGAT2L6

306

Q6ZPD8
RLHISEFLYDKALTF

DHX57

386

Q6P158
IFELSKIIFHRLYSL

CYP4X1

216

Q8N118
RLYSLLYHSDIIFKL

CYP4X1

226

Q8N118
SHYLLFLQAISLFLL

DPY19L4

266

Q7Z388
KANHVFFLLYLLHIL

FADS1

126

O60427
LSFREFLLIFHKAAA

EFHD1

146

Q9BUP0
FLHNSKLLEYFRIFA

FMO2

81

Q99518
LRDRYSFFHKLIPLL

DNAAF5

276

Q86Y56
IFKLIIEFLFLYLLH

GJB3

136

O75712
FLLRLAGLDYELAHK

SCUBE3

596

Q8IX30
LKLFHSLKLLVDYCF

SACS

3126

Q9NZJ4
VKYRARFFHLADLFL

NOC4L

341

Q9BVI4
MRIHYLLFALLFLFL

DEFB103A

1

P81534
YKRLLDSGAFHLLLD

MOCS3

341

O95396
IFFFRQTLKLLLCYH

CPT1B

121

Q92523
SLLVLTRKHFLDYFD

MTBP

501

Q96DY7
NFLAKLYLARHVLIL

PANX2

221

Q96RD6
YLLKIANFSNLLFLH

TAS2R50

106

P59544
LALSLRLLVYRSLHF

SLC35G3

201

Q8N808
DVFYNRLLKSRILFH

TCAIM

346

Q8N3R3
ALYHCQVFLKRFLRL

TMEM229A

166

B2RXF0
LTARALDLSLKYHFV

ITIH3

581

Q06033
RALLFLSYILTHFIF

PKDREJ

1706

Q9NTG1
LSYILTHFIFLALLL

PKDREJ

1711

Q9NTG1
FLRKHFLATGIIRFY

PKDREJ

2016

Q9NTG1
FAAIYFLLVERLKSH

SIK2

326

Q9H0K1
SHAMDALLFRLYLLF

HTR3D

426

Q70Z44
FLSSLKFHIRRFIFL

TAS2R1

246

Q9NYW7
LKLAFSEFYLSLILL

XPR1

131

Q9UBH6
YLILKLLEFFGHLRT

RNFT1

331

Q5M7Z0
ASHRKYLFSLALLLN

SLC16A5

301

O15375
ARTFYLIKDIRFLLH

PES1

61

O00541
KKYLRHVFLFEDLIL

PLEKHG4B

1016

Q96PX9
HTLLAISFFSERKYL

SCTR

241

P47872
LTVLFLKFLEYFHKL

PIEZO2

916

Q9H5I5
LLLAEAYRLKFAFAD

TBC1D22A

496

Q8WUA7
LILTLLRFSYDQKYH

USP38

761

Q8NB14
LYRHFKNTLIFAVLA

TMEM87B

391

Q96K49
LAALHMLFLLYLHFA

YIPF3

281

Q9GZM5
LHINLLKFAFSIRAY

UGGT2

101

Q9NYU1
LHQFYLASLKLTFLL

ZP2

331

Q05996
ELAQAYLALFLKLHL

WDR36

891

Q8NI36
LITLFHLFLFKLIYN

KIAA2013

601

Q8IYS2
VKFYLAELALALDHL

RPS6KA2

161

Q15349
KAFHFYLTRALQLLR

ART3

136

Q13508