Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	UNC13B PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 CUBN PCDHGA8 MEX3B UNC13A	1.52e-06	749	49	11	GO:0005509
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	2.42e-07	187	48	7	GO:0007156
GeneOntologyBiologicalProcess	dense core granule docking	UNC13B UNC13A	5.30e-06	2	48	2	GO:0061790
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	7.48e-06	313	48	7	GO:0098742
GeneOntologyBiologicalProcess	embryo development	SOX10 SEC24D CDX1 KMT2D EYA4 LPA HIPK2 CC2D2A DLG4 TBXT CUBN PTCH1 TFAP2A	1.66e-05	1437	48	13	GO:0009790
GeneOntologyBiologicalProcess	pattern specification process	CDX1 HIPK2 CC2D2A TBXT NKX2-2 FGFR4 PTCH1 TFAP2A	2.61e-05	526	48	8	GO:0007389
GeneOntologyBiologicalProcess	dense core granule priming	UNC13B UNC13A	3.17e-05	4	48	2	GO:0061789
GeneOntologyBiologicalProcess	chordate embryonic development	SOX10 SEC24D CDX1 KMT2D LPA CC2D2A TBXT CUBN PTCH1 TFAP2A	3.64e-05	906	48	10	GO:0043009
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	SOX10 SEC24D CDX1 KMT2D LPA CC2D2A TBXT CUBN PTCH1 TFAP2A	4.50e-05	929	48	10	GO:0009792
GeneOntologyBiologicalProcess	lens induction in camera-type eye	HIPK2 TFAP2A	1.11e-04	7	48	2	GO:0060235
GeneOntologyBiologicalProcess	regionalization	CDX1 HIPK2 CC2D2A TBXT NKX2-2 FGFR4 PTCH1	1.11e-04	478	48	7	GO:0003002
GeneOntologyBiologicalProcess	developmental induction	HIPK2 FGFR4 TFAP2A	1.18e-04	41	48	3	GO:0031128
GeneOntologyBiologicalProcess	nerve development	UNC13B NKX2-2 TFAP2A UNC13A	1.20e-04	109	48	4	GO:0021675
GeneOntologyBiologicalProcess	neural tube closure	CC2D2A TBXT PTCH1 TFAP2A	1.38e-04	113	48	4	GO:0001843
GeneOntologyBiologicalProcess	tube closure	CC2D2A TBXT PTCH1 TFAP2A	1.43e-04	114	48	4	GO:0060606
GeneOntologyBiologicalProcess	primary neural tube formation	CC2D2A TBXT PTCH1 TFAP2A	1.74e-04	120	48	4	GO:0014020
GeneOntologyBiologicalProcess	extracellular matrix organization	LPA ADAMTS20 FGFR4 COLGALT1 TFAP2A IMPG2	2.30e-04	377	48	6	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	LPA ADAMTS20 FGFR4 COLGALT1 TFAP2A IMPG2	2.33e-04	378	48	6	GO:0043062
GeneOntologyBiologicalProcess	presynaptic dense core vesicle exocytosis	UNC13B UNC13A	2.36e-04	10	48	2	GO:0099525
GeneOntologyBiologicalProcess	external encapsulating structure organization	LPA ADAMTS20 FGFR4 COLGALT1 TFAP2A IMPG2	2.37e-04	379	48	6	GO:0045229
GeneOntologyBiologicalProcess	neural tube formation	CC2D2A TBXT PTCH1 TFAP2A	2.66e-04	134	48	4	GO:0001841
GeneOntologyBiologicalProcess	embryonic organ development	EYA4 LPA HIPK2 CC2D2A TBXT PTCH1 TFAP2A	2.97e-04	561	48	7	GO:0048568
GeneOntologyBiologicalProcess	positive regulation of nervous system process	UNC13B SOX10 WASF3	3.17e-04	57	48	3	GO:0031646
GeneOntologyBiologicalProcess	neuronal dense core vesicle exocytosis	UNC13B UNC13A	3.45e-04	12	48	2	GO:0099011
GeneOntologyBiologicalProcess	oligodendrocyte development	SOX10 WASF3 NKX2-2	3.51e-04	59	48	3	GO:0014003
GeneOntologyBiologicalProcess	regulation of synaptic vesicle priming	UNC13B UNC13A	4.74e-04	14	48	2	GO:0010807
GeneOntologyBiologicalProcess	neural plate development	TBXT PTCH1	4.74e-04	14	48	2	GO:0001840
GeneOntologyBiologicalProcess	embryonic epithelial tube formation	CC2D2A TBXT PTCH1 TFAP2A	5.08e-04	159	48	4	GO:0001838
GeneOntologyBiologicalProcess	neuromuscular junction development	UNC13B SORBS2 UNC13A	5.33e-04	68	48	3	GO:0007528
GeneOntologyBiologicalProcess	dense core granule exocytosis	UNC13B UNC13A	5.46e-04	15	48	2	GO:1990504
GeneOntologyBiologicalProcess	epithelial tube formation	CC2D2A TBXT PTCH1 TFAP2A	6.98e-04	173	48	4	GO:0072175
GeneOntologyBiologicalProcess	synaptic vesicle docking	UNC13B UNC13A	7.05e-04	17	48	2	GO:0016081
GeneOntologyBiologicalProcess	regulation of nervous system process	UNC13B SOX10 WASF3 DLG4	7.28e-04	175	48	4	GO:0031644
GeneOntologyBiologicalProcess	cell-cell adhesion	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 DLG4 PCDHGA8 MEX3B	7.42e-04	1077	48	9	GO:0098609
GeneOntologyBiologicalProcess	smoothened signaling pathway	HIPK2 CC2D2A NKX2-2 PTCH1	7.44e-04	176	48	4	GO:0007224
GeneOntologyBiologicalProcess	tube formation	CC2D2A TBXT PTCH1 TFAP2A	9.32e-04	187	48	4	GO:0035148
GeneOntologyBiologicalProcess	regulation of neuronal synaptic plasticity	UNC13B DLG4 UNC13A	9.54e-04	83	48	3	GO:0048168
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	CC2D2A TBXT PTCH1 TFAP2A	9.89e-04	190	48	4	GO:0016331
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	SOX10 CDX1 KMT2D SUPT5H GPS2 HIPK2 TBXT NKX2-2 TFAP2A SP7	1.16e-03	1390	48	10	GO:0045944
GeneOntologyBiologicalProcess	regulation of short-term neuronal synaptic plasticity	UNC13B UNC13A	1.19e-03	22	48	2	GO:0048172
GeneOntologyBiologicalProcess	neural tube development	CC2D2A TBXT PTCH1 TFAP2A	1.24e-03	202	48	4	GO:0021915
GeneOntologyBiologicalProcess	embryonic pattern specification	TBXT PTCH1 TFAP2A	1.24e-03	91	48	3	GO:0009880
GeneOntologyBiologicalProcess	somite development	CDX1 TBXT PTCH1	1.37e-03	94	48	3	GO:0061053
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	UNC13B BSN UNC13A	2.07e-05	23	49	3	GO:0098831
GeneOntologyCellularComponent	cell cortex region	UNC13B BSN UNC13A	1.60e-04	45	49	3	GO:0099738
MousePheno	abnormal melanoblast migration	SOX10 ADAMTS20	2.04e-05	3	37	2	MP:0009784
MousePheno	abnormal melanoblast physiology	SOX10 ADAMTS20	2.04e-05	3	37	2	MP:0030904
MousePheno	abnormal neuropore morphology	CC2D2A TBXT PTCH1 TFAP2A	4.90e-05	77	37	4	MP:0012542
MousePheno	pulmonary valve atresia	CC2D2A TFAP2A	1.02e-04	6	37	2	MP:0006130
Domain	Cadherin_tail	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	5.31e-12	37	49	7	PF15974
Domain	Cadherin_CBD	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	5.31e-12	37	49	7	IPR031904
Domain	Cadherin_C_2	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.38e-11	42	49	7	PF16492
Domain	Cadherin_C	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.38e-11	42	49	7	IPR032455
Domain	Cadherin_N	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	3.39e-10	65	49	7	IPR013164
Domain	Cadherin_2	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	3.39e-10	65	49	7	PF08266
Domain	Cadherin_CS	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.33e-08	109	49	7	IPR020894
Domain	Cadherin	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.71e-08	113	49	7	PF00028
Domain	CADHERIN_1	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.71e-08	113	49	7	PS00232
Domain	CADHERIN_2	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.82e-08	114	49	7	PS50268
Domain	-	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.82e-08	114	49	7	2.60.40.60
Domain	CA	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.94e-08	115	49	7	SM00112
Domain	Cadherin-like	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	2.06e-08	116	49	7	IPR015919
Domain	Cadherin	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	2.32e-08	118	49	7	IPR002126
Domain	Unc-13	UNC13B UNC13A	2.02e-05	3	49	2	IPR027080
Domain	EYA_fam	EYA4 EYA3	4.03e-05	4	49	2	IPR028472
Domain	EYA_dom	EYA4 EYA3	4.03e-05	4	49	2	IPR006545
Domain	Munc13_dom-2	UNC13B UNC13A	6.71e-05	5	49	2	IPR014772
Domain	Membr_traf_MHD	UNC13B UNC13A	6.71e-05	5	49	2	PF10540
Domain	DUF1041	UNC13B UNC13A	6.71e-05	5	49	2	SM01145
Domain	MHD2	UNC13B UNC13A	6.71e-05	5	49	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13A	6.71e-05	5	49	2	IPR019558
Domain	DUF1041	UNC13B UNC13A	1.40e-04	7	49	2	PF06292
Domain	Munc13_1	UNC13B UNC13A	1.40e-04	7	49	2	IPR014770
Domain	CAPS_dom	UNC13B UNC13A	1.40e-04	7	49	2	IPR010439
Domain	MHD1	UNC13B UNC13A	1.40e-04	7	49	2	PS51258
Domain	C2	UNC13B CC2D2A UNC13A	4.91e-03	131	49	3	PF00168
Domain	C2	UNC13B CC2D2A UNC13A	5.56e-03	137	49	3	SM00239
Domain	C2	UNC13B CC2D2A UNC13A	6.14e-03	142	49	3	PS50004
Domain	Znf_FYVE_PHD	KMT2D ANKIB1 BSN	6.75e-03	147	49	3	IPR011011
Domain	-	UNC13B CC2D2A UNC13A	6.88e-03	148	49	3	2.60.40.150
Domain	HMG_box	SOX10 KMT2D	8.53e-03	53	49	2	PF00505
Domain	HMG	SOX10 KMT2D	8.85e-03	54	49	2	SM00398
Domain	C2_dom	UNC13B CC2D2A UNC13A	9.11e-03	164	49	3	IPR000008
Domain	-	SOX10 KMT2D	9.16e-03	55	49	2	1.10.30.10
Domain	C1_1	UNC13B UNC13A	9.82e-03	57	49	2	PF00130
Domain	TSP_1	SPON2 ADAMTS20	1.19e-02	63	49	2	PF00090
Domain	ZF_DAG_PE_1	UNC13B UNC13A	1.23e-02	64	49	2	PS00479
Pathway	WP_CELL_LINEAGE_MAP_FOR_NEURONAL_DIFFERENTIATION	SOX10 DLG4 TBXT BSN UNC13A	1.10e-05	132	32	5	M48110
Pubmed	A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 DLG4 NKX2-2 BSN	6.85e-18	44	49	9	19029045
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3	2.82e-14	15	49	6	23515096
Pubmed	Functional significance of isoform diversification in the protocadherin gamma gene cluster.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 BSN	3.68e-14	34	49	7	22884324
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3	2.09e-12	28	49	6	15347688
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	6.40e-12	68	49	7	11230163
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	9.68e-12	72	49	7	10380929
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.18e-11	74	49	7	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.57e-11	77	49	7	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	2.07e-11	80	49	7	10716726
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3	1.96e-10	57	49	6	32633719
Pubmed	Sulfatase 1 promotes the motor neuron-to-oligodendrocyte fate switch by activating Shh signaling in Olig2 progenitors of the embryonic ventral spinal cord.	SOX10 NKX2-2 PTCH1	4.30e-07	11	49	3	23238718
Pubmed	Foxa1 and Foxa2 are required for formation of the intervertebral discs.	TBXT NKX2-2 PTCH1	5.73e-07	12	49	3	23383217
Pubmed	Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis.	TBXT NKX2-2 PTCH1	5.73e-07	12	49	3	18590718
Pubmed	A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis.	SOX10 PTCH1 TFAP2A SP7	9.68e-07	53	49	4	38466355
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3	1.39e-06	58	49	4	30377227
Pubmed	Hedgehog signalling in the mouse requires intraflagellar transport proteins.	TBXT NKX2-2 PTCH1	1.45e-06	16	49	3	14603322
Pubmed	Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain.	SOX10 NKX2-2 PTCH1	1.76e-06	17	49	3	17678855
Pubmed	Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression.	TBXT NKX2-2 PTCH1	1.76e-06	17	49	3	37315133
Pubmed	Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.	SOX10 PTCH1 TFAP2A	1.76e-06	17	49	3	18330926
Pubmed	Multiple essential roles for primary cilia in heart development.	SOX10 PTCH1 TFAP2A	1.76e-06	17	49	3	23351706
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	1.94e-06	2	49	2	12070347
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	1.94e-06	2	49	2	12871971
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	1.94e-06	2	49	2	17561838
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	1.94e-06	2	49	2	23070049
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	1.94e-06	2	49	2	28489077
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	1.94e-06	2	49	2	10440375
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	1.94e-06	2	49	2	22066784
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	1.94e-06	2	49	2	32187536
Pubmed	Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.	UNC13B UNC13A	1.94e-06	2	49	2	28772123
Pubmed	Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.	UNC13B UNC13A	1.94e-06	2	49	2	17267576
Pubmed	Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.	UNC13B UNC13A	1.94e-06	2	49	2	22814762
Pubmed	Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.	UNC13B UNC13A	1.94e-06	2	49	2	28426965
Pubmed	A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.	UNC13B UNC13A	1.94e-06	2	49	2	35613050
Pubmed	Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.	UNC13B UNC13A	1.94e-06	2	49	2	23770256
Pubmed	Membrane bridging by Munc13-1 is crucial for neurotransmitter release.	UNC13B UNC13A	1.94e-06	2	49	2	30816091
Pubmed	Retracing Schwann Cell Developmental Transitions in Embryonic Dissociated DRG/Schwann Cell Cocultures in Mice.	SOX10 TFAP2A	1.94e-06	2	49	2	34093128
Pubmed	A common molecular basis for membrane docking and functional priming of synaptic vesicles.	UNC13B UNC13A	1.94e-06	2	49	2	19558619
Pubmed	Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.	UNC13B UNC13A	1.94e-06	2	49	2	18701688
Pubmed	Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.	UNC13B UNC13A	1.94e-06	2	49	2	31851910
Pubmed	Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.	UNC13B UNC13A	1.94e-06	2	49	2	11832228
Pubmed	Munc13 controls the location and efficiency of dense-core vesicle release in neurons.	UNC13B UNC13A	1.94e-06	2	49	2	23229896
Pubmed	Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.	UNC13B UNC13A	1.94e-06	2	49	2	11792326
Pubmed	Keratan Sulfate Regulates the Switch from Motor Neuron to Oligodendrocyte Generation During Development of the Mouse Spinal Cord.	SOX10 NKX2-2 PTCH1	2.11e-06	18	49	3	26869039
Pubmed	ATX expression and LPA signalling are vital for the development of the nervous system.	SOX10 PTCH1 TFAP2A	2.11e-06	18	49	3	20079728
Pubmed	Ciliary Hedgehog signaling regulates cell survival to build the facial midline.	CC2D2A TBXT PTCH1	2.51e-06	19	49	3	34672258
Pubmed	mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.	DLG4 BSN UNC13A	2.95e-06	20	49	3	23791195
Pubmed	Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion.	SOX10 NKX2-2 TFAP2A	2.95e-06	20	49	3	21377456
Pubmed	Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.	ADAMTS20 NKX2-2 PTCH1	4.56e-06	23	49	3	30814516
Pubmed	Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition.	TBXT NKX2-2 PTCH1	4.56e-06	23	49	3	16357211
Pubmed	The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells.	DLG4 BSN TFAP2A	5.21e-06	24	49	3	35179492
Pubmed	Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.	UNC13B UNC13A	5.83e-06	3	49	2	37343100
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13A	5.83e-06	3	49	2	23658173
Pubmed	Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.	UNC13B UNC13A	5.83e-06	3	49	2	17639022
Pubmed	Transcription factor induction of human oligodendrocyte progenitor fate and differentiation.	SOX10 NKX2-2	5.83e-06	3	49	2	24982138
Pubmed	Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.	KMT2D PTCH1	5.83e-06	3	49	2	22183980
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13A	5.83e-06	3	49	2	33105896
Pubmed	Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.	UNC13B UNC13A	5.83e-06	3	49	2	22966208
Pubmed	Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis.	TBXT SP7	5.83e-06	3	49	2	31909538
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13B UNC13A	5.83e-06	3	49	2	15988013
Pubmed	Association of megacolon with a new dominant spotting gene (Dom) in the mouse.	SOX10 ADAMTS20	5.83e-06	3	49	2	6512238
Pubmed	Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.	UNC13B DLG4 UNC13A	6.68e-06	26	49	3	17124501
Pubmed	Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo.	TBXT NKX2-2 PTCH1	7.51e-06	27	49	3	24706806
Pubmed	Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.	NKX2-2 PTCH1 TFAP2A	8.40e-06	28	49	3	26884322
Pubmed	Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling.	SOX10 PTCH1 TFAP2A	1.04e-05	30	49	3	16368932
Pubmed	Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord.	SOX10 NKX2-2 PTCH1	1.04e-05	30	49	3	23482494
Pubmed	The synaptic vesicle cycle.	UNC13B BSN UNC13A	1.15e-05	31	49	3	15217342
Pubmed	Perinatal lethality (ple): a mutation caused by integration of a transgene into distal mouse chromosome 15.	SOX10 ADAMTS20	1.16e-05	4	49	2	2744761
Pubmed	Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo.	UNC13B UNC13A	1.16e-05	4	49	2	10488064
Pubmed	Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.	DLG4 BSN	1.16e-05	4	49	2	25709106
Pubmed	Molecular basis of estrogen-induced cyclooxygenase type 1 upregulation in endothelial cells.	TFAP2A PTGS1	1.16e-05	4	49	2	15705965
Pubmed	Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.	UNC13B UNC13A	1.16e-05	4	49	2	19996097
Pubmed	Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing.	UNC13B UNC13A	1.16e-05	4	49	2	15123597
Pubmed	ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.	UNC13B UNC13A	1.16e-05	4	49	2	28264913
Pubmed	Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis.	EYA4 EYA3	1.16e-05	4	49	2	19901965
Pubmed	Ibuprofen slows migration and inhibits bowel colonization by enteric nervous system precursors in zebrafish, chick and mouse.	SOX10 PTGS1	1.16e-05	4	49	2	26586201
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	UNC13B UNC13A	1.94e-05	5	49	2	34706221
Pubmed	Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes.	SOX10 SP7	1.94e-05	5	49	2	37102702
Pubmed	Cellular Functions of the Autism Risk Factor PTCHD1 in Mice.	DLG4 PTCH1	1.94e-05	5	49	2	29118110
Pubmed	A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.	UNC13B UNC13A	1.94e-05	5	49	2	32755572
Pubmed	The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation.	SOX10 NKX2-2	1.94e-05	5	49	2	38546197
Pubmed	RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.	UNC13B UNC13A	1.94e-05	5	49	2	22248876
Pubmed	Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor.	TBXT TFAP2A	1.94e-05	5	49	2	36154671
Pubmed	Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations.	SOX10 TFAP2A	1.94e-05	5	49	2	26755698
Pubmed	Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.	UNC13B UNC13A	1.94e-05	5	49	2	33139401
Pubmed	Characterization of the cDNA coding for mouse plasminogen and localization of the gene to mouse chromosome 17.	LPA TBXT	1.94e-05	5	49	2	2081600
Pubmed	Detailed physical and genetic mapping in the region of plasminogen, D17Rp17e, and quaking.	LPA TBXT	1.94e-05	5	49	2	8111116
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	UNC13B UNC13A	1.94e-05	5	49	2	26575293
Pubmed	Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling.	SOX10 NKX2-2 PTCH1	2.14e-05	38	49	3	25936505
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 CC2D2A BSN DMWD PCDHGA8	2.73e-05	1442	49	10	35575683
Pubmed	Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation.	CDX1 TBXT	2.91e-05	6	49	2	11959827
Pubmed	twist is required in head mesenchyme for cranial neural tube morphogenesis.	TBXT TFAP2A	2.91e-05	6	49	2	7729687
Pubmed	A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.	BSN UNC13A	2.91e-05	6	49	2	19812333
Pubmed	Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy.	SOX10 TFAP2A	2.91e-05	6	49	2	31142747
Pubmed	The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting.	BSN UNC13A	2.91e-05	6	49	2	31787876
Pubmed	Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand.	NKX2-2 PTCH1	2.91e-05	6	49	2	25231763
Pubmed	Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles.	UNC13B UNC13A	2.91e-05	6	49	2	28635948
Pubmed	Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.	SOX10 NKX2-2	2.91e-05	6	49	2	17098222
Pubmed	Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry.	SOX10 TFAP2A	2.91e-05	6	49	2	15198977
Pubmed	Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.	BSN UNC13A	2.91e-05	6	49	2	14734538
Pubmed	EYA4, a novel vertebrate gene related to Drosophila eyes absent.	EYA4 EYA3	2.91e-05	6	49	2	9887327
Interaction	PCDHGA4 interactions	PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.63e-08	34	48	5	int:PCDHGA4
Interaction	PCDHGA7 interactions	PCDHGB1 PCDHGA7 PCDHGA6 PCDHGA4	3.45e-07	25	48	4	int:PCDHGA7
Interaction	PCDHGA9 interactions	PCDHGB1 PCDHGA4 PCDHGA3 PCDHGA8	1.10e-06	33	48	4	int:PCDHGA9
Interaction	GPS2 interactions	SOX10 EYA4 SUPT5H GPS2 TBXT SP7	1.15e-06	144	48	6	int:GPS2
Interaction	PCDHGA12 interactions	PCDHGB1 PCDHGA7 PCDHGA4	1.50e-06	10	48	3	int:PCDHGA12
Interaction	SIX4 interactions	EYA4 TBXT EYA3 SP7	4.29e-06	46	48	4	int:SIX4
Interaction	H2BC5 interactions	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.25e-05	331	48	7	int:H2BC5
Interaction	DCHS1 interactions	PCDHGB1 PCDHGA7 PCDHGA6	1.41e-05	20	48	3	int:DCHS1
Interaction	PCDHGA5 interactions	PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA8	1.52e-05	63	48	4	int:PCDHGA5
Interaction	PCDHGA6 interactions	PCDHGA7 PCDHGA6 PCDHGA4	2.48e-05	24	48	3	int:PCDHGA6
Interaction	ATXN1L interactions	SOX10 EYA4 FAM168A TBXT SP7	2.83e-05	150	48	5	int:ATXN1L
Interaction	NCOR2 interactions	SOX10 EYA4 SUPT5H GPS2 TBXT SP7	3.69e-05	264	48	6	int:NCOR2
Interaction	KMT2D interactions	SOX10 KMT2D SUPT5H TBXT SP7	5.00e-05	169	48	5	int:KMT2D
Interaction	BCL9 interactions	SOX10 EYA4 TBXT SP7	5.21e-05	86	48	4	int:BCL9
Interaction	PROSER1 interactions	SOX10 EYA4 SP7	5.44e-05	31	48	3	int:PROSER1
Interaction	PCDHGA8 interactions	PCDHGA4 PCDHGA8	5.53e-05	5	48	2	int:PCDHGA8
Interaction	PCDHA9 interactions	PCDHGA11 PCDHGA6 PCDHGA4	5.99e-05	32	48	3	int:PCDHA9
Interaction	ARID1B interactions	SOX10 FAM168A SUPT5H TBXT SP7	6.23e-05	177	48	5	int:ARID1B
Interaction	ZNF608 interactions	SOX10 EYA4 TBXT SP7	7.08e-05	93	48	4	int:ZNF608
Interaction	NFIA interactions	SOX10 KMT2D GPS2 TBXT SP7	8.28e-05	188	48	5	int:NFIA
Interaction	HNF1B interactions	SOX10 KMT2D EYA4 GPS2 SP7	8.71e-05	190	48	5	int:HNF1B
Interaction	NFIC interactions	SOX10 KMT2D GPS2 TBXT SP7	1.39e-04	210	48	5	int:NFIC
Interaction	RYK interactions	PCDHGA11 PCDHGA7 PCDHGA6 WASF3 FGFR4	1.46e-04	212	48	5	int:RYK
Interaction	LINC02370 interactions	UNC13B PDE4DIP	1.54e-04	8	48	2	int:LINC02370
Interaction	PCDHGB2 interactions	PCDHGB1 PCDHGA11 PCDHGA6	1.57e-04	44	48	3	int:PCDHGB2
Interaction	LDB1 interactions	SOX10 EYA4 TBXT SP7	1.61e-04	115	48	4	int:LDB1
Interaction	SSBP3 interactions	EYA4 SUPT5H TBXT SP7	1.84e-04	119	48	4	int:SSBP3
Interaction	PCDHGA3 interactions	PCDHGA4 PCDHGA3	1.98e-04	9	48	2	int:PCDHGA3
Interaction	PAGR1 interactions	KMT2D TBXT SP7	2.44e-04	51	48	3	int:PAGR1
Interaction	TLE3 interactions	KMT2D GPS2 TBXT NKX2-2 EYA3 SP7	2.57e-04	376	48	6	int:TLE3
Interaction	PCDHGC3 interactions	PCDHGB1 PCDHGA6 PCDHGA4	2.89e-04	54	48	3	int:PCDHGC3
Interaction	TBL1X interactions	SOX10 GPS2 TBXT SP7	3.24e-04	138	48	4	int:TBL1X
Interaction	VPS37C interactions	SORBS2 FAM168A GPS2 MEX3B	3.52e-04	141	48	4	int:VPS37C
Interaction	NCOA2 interactions	SOX10 EYA4 TBXT SP7	3.52e-04	141	48	4	int:NCOA2
Interaction	NFIB interactions	SOX10 KMT2D TBXT SP7	3.61e-04	142	48	4	int:NFIB
Interaction	WDR33 interactions	EYA4 SUPT5H WASF3 SP7	3.91e-04	145	48	4	int:WDR33
Interaction	ZNF609 interactions	SOX10 EYA4 TBXT SP7	4.02e-04	146	48	4	int:ZNF609
Interaction	FBRSL1 interactions	EYA4 TBXT SP7	4.14e-04	61	48	3	int:FBRSL1
Interaction	CHD7 interactions	SOX10 SUPT5H TBXT SP7	4.45e-04	150	48	4	int:CHD7
Interaction	GSE1 interactions	EYA4 SUPT5H TBXT SP7	4.91e-04	154	48	4	int:GSE1
Interaction	BICRA interactions	EYA4 SUPT5H SP7	5.46e-04	67	48	3	int:BICRA
Interaction	KDM6A interactions	SOX10 KMT2D TBXT SP7	5.94e-04	162	48	4	int:KDM6A
Cytoband	5q31	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	4.05e-11	115	49	7	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	3.08e-08	298	49	7	chr5q31
Cytoband	19p13.11	COLGALT1 UNC13A	2.79e-03	73	49	2	19p13.11
GeneFamily	Clustered protocadherins	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.22e-11	64	31	7	20
GeneFamily	UNC13 homologs	UNC13B UNC13A	1.70e-05	4	31	2	836
GeneFamily	EYA transcriptional coactivator and phosphatases	EYA4 EYA3	1.70e-05	4	31	2	1044
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EYA4 PCDHGA3 WASF3 TPRG1 FGFR4 SP7	5.38e-08	185	49	6	0094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|343B / Donor, Lineage, Cell class and subclass (all cells)	EYA4 BMP2K PCDHGA8 MEX3B RUBCN	1.18e-06	169	49	5	2098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B PCDHGA6 PCDHGA4 ADAMTS20 UNC13A	1.65e-06	181	49	5	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 SORBS2 PCDHGA6 ADAMTS20 NKX2-2	1.88e-06	186	49	5	adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX10 SORBS2 ADAMTS20 TFAP2A	3.82e-05	172	49	4	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	UNC13B EYA4 WASF3 MS4A15	4.00e-05	174	49	4	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EYA4 SORBS2 PDE4DIP SP7	4.27e-05	177	49	4	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPON2 DLG4 NKX2-2 UNC13A	4.86e-05	183	49	4	d26c7b79895de28961b8d68351f28d4bb531c75c
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC13B EYA4 WASF3 MS4A15	4.97e-05	184	49	4	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC13B EYA4 WASF3 MS4A15	4.97e-05	184	49	4	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 SORBS2 ADAMTS20 NKX2-2	5.29e-05	187	49	4	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 SORBS2 ADAMTS20 NKX2-2	5.29e-05	187	49	4	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	facs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX10 SORBS2 ADAMTS20 FGFR4	5.40e-05	188	49	4	794fc1d9a726945c42f7eac221eed938309b47a9
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SCRT2 PCDHGB1 TFAP2A MEX3B	5.51e-05	189	49	4	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A PTGS1	5.86e-05	192	49	4	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A PTGS1	5.86e-05	192	49	4	40f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 PDE4DIP USP9Y PTGS1	5.86e-05	192	49	4	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A PTGS1	5.98e-05	193	49	4	e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A PTGS1	6.10e-05	194	49	4	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A PTGS1	6.10e-05	194	49	4	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TTC14 USP9Y PTCH1 IMPG2	6.47e-05	197	49	4	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDX1 SORBS2 BMP2K FGFR4	6.60e-05	198	49	4	ad9fb53cd216af9bc9998d6b3bd0255b45e0dbfb
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDX1 SORBS2 BMP2K FGFR4	6.60e-05	198	49	4	edf3e1c2be9df5690492b9c8fc25e7e48ed5c92c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	PDE4DIP ANKIB1 BSN PCDHGA8	6.73e-05	199	49	4	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	Tracheal-10x5prime-Stromal-Schwann-Schwann_Myelinating\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SOX10 PCDHGA3 CUBN MEX3B	6.73e-05	199	49	4	2b567b6fd8addf059bbf2b72c55a7647aefdc595
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Proliferative_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX10 EYA4 PTGS1	3.85e-04	129	49	3	0dcce7cb95bb3593626ecb34ed9da58c7de4e016
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_smooth_muscle-like\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PCDHGA7 SPON2 DLG4	4.12e-04	132	49	3	9633653dba1edee47d915212fb6e68426da49de5
ToppCell	Control-B_memory-6\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SCRT2 HIPK2 PTCH1	4.50e-04	136	49	3	94f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	KMT2D TTC14 USP9Y	5.64e-04	147	49	3	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 PTGS1	5.64e-04	147	49	3	64fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell	metastatic_Brain-T/NK_cells-Naive_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	SOX10 DLG4 PCDHGA8	5.64e-04	147	49	3	4f7a0c287721befeffabf95b8c5f9ff64149c7c1
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBXT CUBN TFAP2A	5.75e-04	148	49	3	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDE4DIP PTCH1 PTGS1	5.87e-04	149	49	3	aedbae2dffa1e880e5c6a146b6d5a135e7f54308
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	BSN UNC13A SP7	5.87e-04	149	49	3	649eb3441fa859591ea85f1ed5fcf08af272a32b
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA7 SPON2 WASF3	6.46e-04	154	49	3	2d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA7 SPON2 WASF3	6.46e-04	154	49	3	0dec222101530f1727184dbb7c03969d3884f111
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EYA4 HIPK2 PTCH1	6.83e-04	157	49	3	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SOX10 SORBS2 TFAP2A	6.95e-04	158	49	3	adad97e6cf479d42791c5ba9cbc5f15f469322bf
ToppCell	ICU-NoSEP-Lymphocyte-T_NK-gdT\|ICU-NoSEP / Disease, Lineage and Cell Type	SPON2 TPRG1 PTCH1	7.21e-04	160	49	3	2798c5bd971407f27dd4d3a4831d63d9c88003c3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A	7.21e-04	160	49	3	7064af50fc10e3ea03badf415306222b74db0f95
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SPON2 PTCH1 PTGS1	7.21e-04	160	49	3	955acb023ce4ccfac5073c9d693db87db3856187
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	FAM168A WASF3 HIPK2	7.34e-04	161	49	3	347edb0de10850b7d16c40945751033289289c9b
ToppCell	AT1_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	EYA4 WASF3 MS4A15	7.48e-04	162	49	3	ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCell	Club_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	MS4A15 BSN PCDHGA8	7.75e-04	164	49	3	4e25e6362ef793b08de2f4d1dccb6b1fc9c072a5
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	7.75e-04	164	49	3	57301178e420983c0cb72178e288a3a0449fdda3
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EYA4 PCDHGA8 MEX3B	7.75e-04	164	49	3	eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDHGA4 DLG4 PTGS1	8.02e-04	166	49	3	a42268a02a89fc97272e45c4cbe21acf04b7428c
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EYA4 SORBS2 TFAP2A	8.02e-04	166	49	3	1df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCell	LPS-antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EYA4 SORBS2 TFAP2A	8.02e-04	166	49	3	9628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC13B SEC24D PTGS1	8.16e-04	167	49	3	f01b96173deda0239fa482989873cf308e49d48c
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC13B SEC24D PTGS1	8.16e-04	167	49	3	5fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	8.16e-04	167	49	3	17c653b46507c8bb85da95836ae72a6015336142
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	8.31e-04	168	49	3	95dc690c1987b05685d36e6bb20eb79308696e30
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	8.31e-04	168	49	3	af82e07d1eec51fc6530155f37addbce6221885d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CUBN DMWD PCDHGA8	8.31e-04	168	49	3	ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	CC2D2A PTCH1 PTGS1	8.31e-04	168	49	3	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5\|TCGA-Bladder / Sample_Type by Project: Shred V9	BSN MEX3B UNC13A	8.45e-04	169	49	3	9c4e83fe8225d16173a103bf5a57b17d623be923
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	EYA4 PCDHGA8 RUBCN	8.45e-04	169	49	3	e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYA4 SORBS2 PDE4DIP	8.59e-04	170	49	3	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 EYA3 TFAP2A	8.59e-04	170	49	3	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B SORBS2 PTGS1	8.59e-04	170	49	3	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	UNC13B EYA4 WASF3	8.59e-04	170	49	3	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B SORBS2 PTGS1	8.59e-04	170	49	3	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP2K PTGS1 IMPG2	8.74e-04	171	49	3	5885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCell	11.5-Airway-Epithelial-Basal_cell\|Airway / Age, Tissue, Lineage and Cell class	PCDHGB1 TPRG1 TFAP2A	8.89e-04	172	49	3	9d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	8.89e-04	172	49	3	bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	UNC13B COLGALT1 PTGS1	8.89e-04	172	49	3	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC\|lymph-node_spleen / Manually curated celltypes from each tissue	UNC13B EYA4 BMP2K	8.89e-04	172	49	3	1b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell	368C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	BMP2K PCDHGA7 PTGS1	9.04e-04	173	49	3	8cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell	368C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	BMP2K PCDHGA7 PTGS1	9.04e-04	173	49	3	fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	FAM168A PDE4DIP PTCH1	9.04e-04	173	49	3	7e2149205e119cec4f5099c83c85d1e13470137a
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	9.04e-04	173	49	3	922356a5b4c84607318ac24d7caa2e235b72b066
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP2K PDE4DIP MEX3B	9.19e-04	174	49	3	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX10 SORBS2 TFAP2A	9.19e-04	174	49	3	0d8e737860120dcd3a6b57992c612595904d585e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	9.19e-04	174	49	3	667035a11b68745fa8446d6c68214713be42710f
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UNC13B NKX2-2 BSN	9.19e-04	174	49	3	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SOX10 SORBS2 TFAP2A	9.19e-04	174	49	3	aceca0a22bb1e380835e792681cfc9b752fb5496
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	9.19e-04	174	49	3	412ccc099028a372b9d953363984c2da54b2187f
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BMP2K PDE4DIP MEX3B	9.34e-04	175	49	3	1b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	UNC13B WASF3 MS4A15	9.34e-04	175	49	3	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	AT1_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	EYA4 WASF3 MS4A15	9.50e-04	176	49	3	4a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCell	facs-Lung-Endomucin-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPRG1 RUBCN IMPG2	9.50e-04	176	49	3	9b58734017ceabe81f490dd0b9f3192bc903d455
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EYA4 SORBS2 PDE4DIP	9.50e-04	176	49	3	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SORBS2 USP9Y PTGS1	9.66e-04	177	49	3	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA4 NKX2-2 UNC13A	9.66e-04	177	49	3	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BMP2K BSN PTGS1	9.66e-04	177	49	3	86c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell	wk_15-18-Epithelial-PNS-Schwann_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SOX10 KMT2D TFAP2A	9.66e-04	177	49	3	5357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX10 SORBS2 TFAP2A	9.66e-04	177	49	3	8c78f7de091f16e86e326a73c9f1429e0232821f
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX10 PCDHGA7 ADAMTS20	9.66e-04	177	49	3	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA4 NKX2-2 UNC13A	9.66e-04	177	49	3	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SOX10 SORBS2 TFAP2A	9.66e-04	177	49	3	621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 BSN TFAP2A	9.66e-04	177	49	3	0417460bdb012bc43d7254377fa53d79cdab3f34
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B SEC24D SORBS2	9.66e-04	177	49	3	4c069f0d044a96118090b85ca592a21d6b5d9399
ToppCell	ILEUM-inflamed-(9)_Enteric_neurons\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SOX10 SORBS2 TFAP2A	9.81e-04	178	49	3	d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDHGA6 PCDHGA3 DLG4	9.81e-04	178	49	3	09475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDHGA6 PCDHGA3 DLG4	9.81e-04	178	49	3	35de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	9.81e-04	178	49	3	a9ba4089413b1c55d667ce836b6972ca572ee2b8
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC24D PDE4DIP BSN	9.81e-04	178	49	3	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SOX10 SORBS2 TFAP2A	9.81e-04	178	49	3	13dfd28a80889c2dacdc65b94a41bb9762dc409d
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA6 PCDHGA4 PTGS1	9.81e-04	178	49	3	09a215a0d6e98e4bb920cabda12af08ff4de3c98
Drug	montmorillonite	SOX10 PCDHGA11 PCDHGA3 PCDHGA8	1.63e-06	40	49	4	CID000517273
Drug	Naringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A	SEC24D EYA4 BMP2K HIPK2 FGFR4 NPEPL1	3.76e-06	195	49	6	4597_DN
Drug	Amrinone [60719-84-8]; Up 200; 21.4uM; PC3; HT_HG-U133A	PDE4DIP HIPK2 FGFR4 PTCH1 DMWD UNC13A	3.99e-06	197	49	6	4488_UP
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; HL60; HT_HG-U133A	UNC13B GPS2 PDE4DIP TFAP2A RUBCN UNC13A	3.99e-06	197	49	6	3019_DN
Drug	Methyldopa (L,-) [555-30-6]; Up 200; 19uM; MCF7; HT_HG-U133A	SOX10 SPON2 HIPK2 EYA3 USP9Y TFAP2A	3.99e-06	197	49	6	3234_UP
Drug	lactofen	CDX1 PCDHGA11 PCDHGA3 PCDHGA8	2.79e-05	81	49	4	CID000062276
Drug	2-phenylpropionic acid	BSN PTGS1	4.52e-05	5	49	2	CID000010296
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; HL60; HT_HG-U133A	BMP2K EYA3 PTCH1 NPEPL1 RUBCN	5.85e-05	193	49	5	2996_DN
Drug	Alexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; HL60; HT_HG-U133A	WASF3 PDE4DIP HIPK2 EYA3 DMWD	6.30e-05	196	49	5	2576_DN
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; HL60; HT_HG-U133A	SORBS2 PDE4DIP HIPK2 CUBN PTGS1	6.45e-05	197	49	5	2181_UP
Drug	Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; HL60; HT_HG-U133A	SEC24D FAM168A SPON2 EYA3 NPEPL1	6.45e-05	197	49	5	6145_DN
Drug	Biperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; PC3; HT_HG-U133A	EYA4 SORBS2 BMP2K EYA3 PTCH1	6.45e-05	197	49	5	4684_DN
Drug	Harmane hydrochloride [21655-84-5]; Up 200; 18.2uM; PC3; HT_HG-U133A	PDE4DIP FGFR4 EYA3 PTCH1 IMPG2	6.61e-05	198	49	5	4584_UP
Drug	Flunixin meglumine [42461-84-7]; Up 200; 8.2uM; PC3; HT_HG-U133A	SORBS2 LPA PDE4DIP TBXT PTGS1	6.61e-05	198	49	5	3713_UP
Drug	Ronidazole [7681-76-7]; Down 200; 20uM; HL60; HT_HG-U133A	SEC24D BMP2K WASF3 EYA3 NPEPL1	6.77e-05	199	49	5	6134_DN
Disease	Sarcosine measurement	PCDHGB1 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.32e-12	23	48	6	EFO_0021668
Disease	mental development measurement	PCDHGB1 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	2.32e-12	25	48	6	EFO_0008230
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	2.35e-11	71	48	7	EFO_0007878, EFO_0007979
Disease	lung squamous cell carcinoma (is_implicated_in)	KMT2D FGFR4 PTCH1	7.98e-06	24	48	3	DOID:3907 (is_implicated_in)
Disease	eye disease (implicated_via_orthology)	EYA4 EYA3	3.87e-05	6	48	2	DOID:5614 (implicated_via_orthology)
Disease	branchiootorenal syndrome (implicated_via_orthology)	EYA4 EYA3	5.41e-05	7	48	2	DOID:14702 (implicated_via_orthology)
Disease	Gastrointestinal Stromal Sarcoma	HIPK2 CC2D2A PTCH1	6.23e-05	47	48	3	C3179349
Disease	Gastrointestinal Stromal Tumors	HIPK2 CC2D2A PTCH1	7.50e-05	50	48	3	C0238198
Disease	Rhabdomyosarcoma	FGFR4 PTCH1	2.68e-04	15	48	2	C0035412
Disease	mean platelet volume	PCDHGB1 PCDHGA11 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA8	1.23e-03	1020	48	7	EFO_0004584
Disease	free cholesterol measurement, low density lipoprotein cholesterol measurement	LPA DLG4 DMWD	1.45e-03	137	48	3	EFO_0004611, EFO_0008591
Disease	stomach cancer (is_marker_for)	KMT2D FGFR4 PTCH1	1.61e-03	142	48	3	DOID:10534 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPYYTTSQPNASVHQ	UNC13A	211	Q9UPW8
QYPDFSSYSHVEPAP	CDX1	41	P47902
HYGPTQPAYSPSQQL	GPS2	196	Q13227
PSNRHSYPQQAPYWT	FGFR4	136	P22455
YPQSQDPYSHVNDPY	TFAP2A	66	P05549
DPYSHVNDPYSLNPL	TFAP2A	71	P05549
PNTSYGEPYQHNTPL	ANKIB1	36	Q9P2G1
HSVYQPQPSASQYPT	BMP2K	521	Q9NSY1
YNVSHPCASAPPQYS	DMWD	241	Q09019
AHSHFPSSPVQPSYY	ADAMTS20	1266	P59510
NDNPPTFPHSSYSVY	PCDHGA7	446	Q9Y5G6
PSPAHYSYPIQASST	EYA3	156	Q99504
NDNPPTFPHASYSAY	PCDHGA8	446	Q9Y5G5
PVFPHSSYSAYIPEN	PCDHGA11	451	Q9Y5H2
PTFPHASYSAYIPEN	PCDHGA4	481	Q9Y5G9
NDNPPTFPHSSYSVY	PCDHGA6	446	Q9Y5G7
LPTQPHLYTYTAPAA	HIPK2	1096	Q9H2X6
AAAPAYNPSLYPTNS	FAM168A	31	Q92567
VSQSPAPTYPSDSHY	BSN	3206	Q9UPA5
PPNHSEGTLPYSYNL	PCDHGB1	736	Q9Y5G3
PNPTDSCPLYLNYAT	NPEPL1	61	Q8NDH3
NLIPSPPTYNSAHDY	PTGS1	121	P23219
NDNPPTFPHLSYSAY	PCDHGA3	446	Q9Y5H0
IHSPNYPSPYRSNTD	CUBN	1521	O60494
SPRSAHQYSPQLYPS	EYA4	131	O95677
PSTYSPTHNADYPLG	CC2D2A	1081	Q9P2K1
LPSYAPENYNSPASL	COLCA2	56	A8K830
TPHSHSRTPEYYPNA	LPA	626	P08519
PSNAYLSDSYAPPDI	DLG4	246	P78352
SPAASAPPAYDNVAY	MS4A15	221	Q8N5U1
ASRNLAFYPPHPDYT	COLGALT1	246	Q8NBJ5
PSSTYTPPNSYAQHS	RUBCN	211	Q92622
ADYSPPSPALSFAHN	MEX3B	316	Q6ZN04
YAPHRLPPSSYDADQ	SCRT2	46	Q9NQ03
SSPSHPANSFYYPRL	SPON2	216	Q9BUD6
NTRYSPPPPYSSHSF	PTCH1	636	Q13635
YSSASTPQYPTAHPL	NKX2-2	251	O95096
SYQPSPSPQSYHQVA	SUPT5H	901	O00267
PSPAGYQNTHSPASY	SUPT5H	916	O00267
YQNTHSPASYHPTPS	SUPT5H	921	O00267
PYPQHPFYSSASGDV	IMPG2	1176	Q9BZV3
AGLYNPPYSAQSHPA	SORBS2	126	O94875
SHAPYQPSAQSSYPG	SEC24D	96	O94855
SGYANDYPPFSHSFP	SP7	86	Q8TDD2
TDYSYPATPNHSLHP	WASF3	246	Q9UPY6
PPHYTDQPSTSQIAY	SOX10	366	P56693
SVTESTLYPNPYHQP	TPRG1	46	Q6ZUI0
PSHSNHGDPLSYYQT	TTC14	171	Q96N46
YRSETSNSFPPPYHT	UNC13B	191	O14795
RSSPYPSPYAHRNNS	TBXT	286	O15178
PSPYAHRNNSPTYSD	TBXT	291	O15178
DAPLYPHSPASQYQQ	USP9Y	2496	O00507
PEPPTQHSYTYNVSN	KMT2D	4886	O14686
DSSYYLNSAQPHSPP	PDE4DIP	1776	Q5VU43