Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	PMS2 ERCC2 ERCC6 ATRX ZRANB3 HELB TOP2B	3.33e-05	127	141	7	GO:0008094
GeneOntologyCellularComponent	symbiont cell surface	GBP2 C4A C4B	1.64e-05	8	141	3	GO:0106139
GeneOntologyCellularComponent	other organism part	GBP2 C4A C4B	2.45e-05	9	141	3	GO:0044217
GeneOntologyCellularComponent	CAK-ERCC2 complex	ERCC2 CCNH	2.69e-04	4	141	2	GO:0070516
Domain	zf-C2H2_6	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 GFI1B ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	7.70e-07	314	141	13	PF13912
Domain	ZF_DAG_PE_1	DEF8 CDC42BPB PLEKHM1 RASSF1 PRKD1 PRKCQ	8.70e-06	64	141	6	PS00479
Domain	ZF_DAG_PE_2	DEF8 CDC42BPB PLEKHM1 RASSF1 PRKD1 PRKCQ	8.70e-06	64	141	6	PS50081
Domain	C1	DEF8 CDC42BPB PLEKHM1 RASSF1 PRKD1 PRKCQ	9.53e-06	65	141	6	SM00109
Domain	PE/DAG-bd	DEF8 CDC42BPB PLEKHM1 RASSF1 PRKD1 PRKCQ	1.04e-05	66	141	6	IPR002219
Domain	LRR_5	TLR7 TSHR FSHR	4.86e-05	10	141	3	PF13306
Domain	LRR_5	TLR7 TSHR FSHR	4.86e-05	10	141	3	IPR026906
Domain	C1_1	DEF8 CDC42BPB RASSF1 PRKD1 PRKCQ	6.98e-05	57	141	5	PF00130
Domain	-	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	1.93e-04	679	141	15	3.30.160.60
Domain	zf-C2H2	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	2.41e-04	693	141	15	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	2.45e-04	694	141	15	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ARID2 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	2.53e-04	775	141	16	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ARID2 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	2.60e-04	777	141	16	PS00028
Domain	Znf_C2H2-like	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ARID2 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	3.40e-04	796	141	16	IPR015880
Domain	Znf_C2H2	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ARID2 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	3.85e-04	805	141	16	IPR007087
Domain	KRAB	ZNF845 ZNF157 ZNF780B ZNF813 ZNF317 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82	3.95e-04	358	141	10	PS50805
Domain	KRAB	ZNF845 ZNF157 ZNF780B ZNF813 ZNF317 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82	3.95e-04	358	141	10	PF01352
Domain	ZnF_C2H2	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ARID2 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	4.01e-04	808	141	16	SM00355
Domain	KRAB	ZNF845 ZNF157 ZNF780B ZNF813 ZNF317 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82	5.01e-04	369	141	10	SM00349
Domain	DAG/PE-bd	CDC42BPB PRKD1 PRKCQ	5.07e-04	21	141	3	IPR020454
Domain	KRAB	ZNF845 ZNF157 ZNF780B ZNF813 ZNF317 ZNF606 ZNF700 ZNF160 ZNF439 ZFP82	5.12e-04	370	141	10	IPR001909
Domain	zf-RING_9	DEF8 PLEKHM1	5.58e-04	5	141	2	PF13901
Domain	Anaphylatoxin_comp_syst	C4A C4B	5.58e-04	5	141	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	5.58e-04	5	141	2	IPR001840
Domain	Zf-RING_9	DEF8 PLEKHM1	5.58e-04	5	141	2	IPR025258
Domain	DUF4206	DEF8 PLEKHM1	5.58e-04	5	141	2	SM01175
Domain	Gphrmn_rcpt_fam	TSHR FSHR	8.32e-04	6	141	2	IPR002131
Domain	ANATO	C4A C4B	1.16e-03	7	141	2	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B	1.16e-03	7	141	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	1.16e-03	7	141	2	PS01177
Domain	ANATO	C4A C4B	1.16e-03	7	141	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	1.16e-03	7	141	2	IPR000020
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	1.54e-03	8	141	2	IPR019565
Domain	Thiol-ester_cl	C4A C4B	1.54e-03	8	141	2	PF10569
Domain	MacrogloblnA2_CS	C4A C4B	1.54e-03	8	141	2	IPR019742
Pathway	BIOCARTA_DNAFRAGMENT_PATHWAY	CASP3 GZMH TOP2B	6.17e-05	11	104	3	MM1349
Pathway	WP_SIDS_SUSCEPTIBILITY_PATHWAYS	CC2D1A DDC AR C4A C4B	7.24e-05	59	104	5	MM15838
Pubmed	High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk.	ERCC2 ERCC6 CCNH	2.89e-07	4	146	3	17728339
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MYH8 ERCC2 ATRX TRIO AFF3 DAPK3 MRPL33 CCNH NF1 AGO1 RASSF1 FIBP AKAP11 PRKD1 IGSF9B LYN HSPA4	3.08e-07	910	146	17	36736316
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF19 NBPF15 NBPF9 NBPF10	1.69e-06	21	146	4	16079250
Pubmed	Nucleotide excision repair gene polymorphisms and risk of advanced colorectal adenoma: XPC polymorphisms modify smoking-related risk.	ERCC2 ERCC6 CCNH	2.51e-06	7	146	3	16492920
Pubmed	Nucleotide excision repair pathway genes and oral premalignant lesions.	ERCC2 ERCC6 CCNH	2.51e-06	7	146	3	17575242
Pubmed	Genetic susceptibility to esophageal cancer: the role of the nucleotide excision repair pathway.	ERCC2 ERCC6 CCNH	4.00e-06	8	146	3	19270000
Pubmed	Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.	ERCC2 ERCC6 ATRX	4.00e-06	8	146	3	9607915
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	ATRX TRIO TUBG2 PREX2 SPATS2L NF1 AGO1 IGSF9B ALB HSPA4 TOP2B	5.75e-06	475	146	11	31040226
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PMS2 ATRX TRIO TUBG2 SYNE1 MBD1 RANBP9 DEF8 LRP1B CDC42BPB RYR3 HEATR6 FIBP IFT122 ZNF606 CADPS2 ZNF439 NIPBL	7.97e-06	1285	146	18	35914814
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ERCC6 NPEPPS SPG11 NSUN7 RYR3 TRANK1 ARID2 COPS7B C4A C4B HYDIN	8.80e-06	497	146	11	36774506
Pubmed	Genome-wide association study identifies eight loci associated with blood pressure.	MECOM PLCD3 RHOBTB1 CLCN6	9.78e-06	32	146	4	19430483
Pubmed	PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis.	DEF8 PLEKHM1 NDEL1	1.17e-05	11	146	3	27777970
Pubmed	Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome.	ATRX CASP3 AR	1.55e-05	12	146	3	21427128
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	1.75e-05	2	146	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	1.75e-05	2	146	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	1.75e-05	2	146	2	15998580
Pubmed	Serum Inflammation Parameters and Survival in Hepatocellular Carcinoma Patients: Importance of Albumin and Gamma-Glutamyltranspeptidase.	GGT1 ALB	1.75e-05	2	146	2	36878197
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	1.75e-05	2	146	2	19062096
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	1.75e-05	2	146	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	1.75e-05	2	146	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	1.75e-05	2	146	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	1.75e-05	2	146	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	1.75e-05	2	146	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	1.75e-05	2	146	2	22387014
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	1.75e-05	2	146	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	1.75e-05	2	146	2	23918728
Pubmed	Predictors for partial suppression of spermatogenesis of hormonal male contraception.	AR FSHR	1.75e-05	2	146	2	18645675
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	1.75e-05	2	146	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	1.75e-05	2	146	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	1.75e-05	2	146	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	1.75e-05	2	146	2	6950384
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	1.75e-05	2	146	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	1.75e-05	2	146	2	8428773
Pubmed	The effects of modulation of gamma-glutamyl transpeptidase activity in HepG2 cells on thiol homeostasis and caspase-3-activity.	CASP3 GGT1	1.75e-05	2	146	2	17141888
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	1.75e-05	2	146	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	1.75e-05	2	146	2	21345967
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	1.75e-05	2	146	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	1.75e-05	2	146	2	2302180
Pubmed	The Cellular Response to Oxidatively Induced DNA Damage and Polymorphism of Some DNA Repair Genes Associated with Clinicopathological Features of Bladder Cancer.	ERCC2 ERCC6	1.75e-05	2	146	2	26649138
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	1.75e-05	2	146	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	1.75e-05	2	146	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	1.75e-05	2	146	2	29080553
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	1.75e-05	2	146	2	6589636
Pubmed	Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models.	AR HSPA4	1.75e-05	2	146	2	36773708
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	1.75e-05	2	146	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	1.75e-05	2	146	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	1.75e-05	2	146	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	1.75e-05	2	146	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	1.75e-05	2	146	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	1.75e-05	2	146	2	3542363
Pubmed	Association of TLR7 and TSHR copy number variation with Graves' disease and Graves' ophthalmopathy in Chinese population in Taiwan.	TLR7 TSHR	1.75e-05	2	146	2	24517461
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	1.75e-05	2	146	2	2387317
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	1.75e-05	2	146	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	1.75e-05	2	146	2	7365238
Pubmed	In human granulosa cells from small antral follicles, androgen receptor mRNA and androgen levels in follicular fluid correlate with FSH receptor mRNA.	AR FSHR	1.75e-05	2	146	2	20843821
Pubmed	Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor.	TSHR FSHR	1.75e-05	2	146	2	25340405
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	1.75e-05	2	146	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	1.75e-05	2	146	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	1.75e-05	2	146	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	1.75e-05	2	146	2	17971229
Pubmed	Synergistic effect of follicle-stimulating hormone receptor and androgen receptor gene variants on semen quality.	AR FSHR	1.75e-05	2	146	2	23013557
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	1.75e-05	2	146	2	6881182
Pubmed	Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death.	CASP3 AR	1.75e-05	2	146	2	12824190
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	1.75e-05	2	146	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	1.75e-05	2	146	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	1.75e-05	2	146	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	1.75e-05	2	146	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	1.75e-05	2	146	2	28873507
Pubmed	Protein kinase C theta is expressed in mast cells and is functionally involved in Fcepsilon receptor I signaling.	PRKCQ LYN	1.75e-05	2	146	2	11358993
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	1.75e-05	2	146	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	1.75e-05	2	146	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	1.75e-05	2	146	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	1.75e-05	2	146	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	1.75e-05	2	146	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	1.75e-05	2	146	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	1.75e-05	2	146	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	1.75e-05	2	146	2	7373044
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	1.75e-05	2	146	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	1.75e-05	2	146	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	1.75e-05	2	146	2	16098595
Pubmed	Methylation of RASSF1A and CDH13 genes in individualized chemotherapy for patients with non-small cell lung cancer.	RASSF1 CDH13	1.75e-05	2	146	2	24998565
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	1.75e-05	2	146	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	1.75e-05	2	146	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	1.75e-05	2	146	2	6559257
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	1.75e-05	2	146	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	1.75e-05	2	146	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	1.75e-05	2	146	2	12480675
Pubmed	SPEF2- and HYDIN-Mutant Cilia Lack the Central Pair-associated Protein SPEF2, Aiding Primary Ciliary Dyskinesia Diagnostics.	SPEF2 HYDIN	1.75e-05	2	146	2	31545650
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	1.75e-05	2	146	2	26800705
Pubmed	ZIP kinase plays a crucial role in androgen receptor-mediated transcription.	DAPK3 AR	1.75e-05	2	146	2	18084323
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	1.75e-05	2	146	2	15390104
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	1.75e-05	2	146	2	1699796
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	1.75e-05	2	146	2	2997024
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	1.75e-05	2	146	2	3624865
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	1.75e-05	2	146	2	21857912
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	1.75e-05	2	146	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	1.75e-05	2	146	2	4514997
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	1.75e-05	2	146	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	1.75e-05	2	146	2	3167981
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	1.75e-05	2	146	2	7545960
GeneFamily	Neuroblastoma breakpoint family	NBPF19 NBPF15 NBPF9 NBPF10	7.79e-06	23	102	4	662
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF845 ZNF157 ZNF780B ZNF813 MECOM ZNF317 ZBTB14 ZSCAN29 GFI1B ZNF606 ZNF700 ZNF160 ZNF439 ZFP82 ZNF646	1.17e-05	718	102	15	28
GeneFamily	Glycoprotein hormone receptors	TSHR FSHR	9.42e-05	3	102	2	199
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC2 ERCC6	6.50e-04	7	102	2	1268
GeneFamily	Complement system\|Sushi domain containing	CFHR5 C4A C4B	1.09e-03	36	102	3	492
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	1.11e-03	9	102	2	1234
Coexpression	PARENT_MTOR_SIGNALING_UP	PMS2 RNGTT TUBG2 NPEPPS SYNE1 RANBP9 GCDH CLSTN1 TFPI TRANK1 HEATR6 PRKD1 IFT122 HSPA4	3.14e-06	567	144	14	M16909
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LCA5 FBXL13 ZNF157 SPEF2 PRKD1 IFT122 HYDIN	8.90e-07	157	146	7	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	Control-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	SYNE1 AFF3 PREX2 FZD4 CADPS2 PLS3 CDH13	2.66e-06	185	146	7	a28187c2fd23564314b35759479ff2ca21f61485
ToppCell	Control-Endothelial-VE_Capillary_A\|Control / Disease state, Lineage and Cell class	SYNE1 AFF3 PREX2 FZD4 CADPS2 PLS3 CDH13	2.85e-06	187	146	7	54d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM GBP2 IFIT3 PREX2 USHBP1 PLXNA2 CDH13	3.06e-06	189	146	7	1d4ad307c0606957dd7bf8da84450e5193cf4a50
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM GBP2 IFIT3 PREX2 USHBP1 PLXNA2 CDH13	3.06e-06	189	146	7	b952026044d5f6c0adce60cf24f6e0199e6f8757
ToppCell	Control-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	SYNE1 AFF3 PREX2 TFPI FZD4 GIMAP8 CADPS2	3.28e-06	191	146	7	c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	SYNE1 MECOM PREX2 GIMAP8 CADPS2 PLXNA2 CDH13	4.02e-06	197	146	7	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATRX TRIO SPEF2 MECOM PREX2 USHBP1 NIPBL	4.44e-06	200	146	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNB2 NBPF19 RHOBTB1 FSHR CADPS2 PLS3	2.09e-05	170	146	6	5de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCell	3'_v3-blood-Mast\|blood / Manually curated celltypes from each tissue	FBXL13 TRIO MECOM RYR3 NDEL1 WSCD2	2.23e-05	172	146	6	e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLSTN1 IFIT3 TFPI USHBP1 PRKD1 ZNF606	2.30e-05	173	146	6	fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell	3'_v3-blood-Mast-Mast_cells\|blood / Manually curated celltypes from each tissue	RYR3 GFI1B NDEL1 WSCD2 ZNF606 ZNF646	2.54e-05	176	146	6	b9da3deaf62622d47eb30b6be7548253eee95597
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	GBP2 CPLX4 IFIT3 HELB TRANK1 SPATS2L	2.79e-05	179	146	6	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	RARRES1 C4A C4B PRKD1 LONRF2 RSPO1	2.88e-05	180	146	6	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SYNE1 AFF3 MECOM TFPI PRKD1 CADPS2	2.88e-05	180	146	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SYNE1 AFF3 FZD4 CADPS2 PLXNA2 CDH13	2.97e-05	181	146	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	cellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CASS4 SYNE1 ZNF780B RASSF1 GZMH PRKCQ	3.06e-05	182	146	6	8ccffcbae28c374fd4161fb0d4cf2c49fae557f6
ToppCell	droplet-Trachea-nan-3m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP2 PREX2 GIMAP8 USHBP1 PLXNA2 CDH13	3.25e-05	184	146	6	fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCell	droplet-Trachea-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP2 PREX2 GIMAP8 USHBP1 PLXNA2 CDH13	3.25e-05	184	146	6	ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell	droplet-Trachea-nan-3m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP2 PREX2 GIMAP8 USHBP1 PLXNA2 CDH13	3.25e-05	184	146	6	1d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCell	droplet-Trachea-nan-3m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP2 PREX2 GIMAP8 USHBP1 PLXNA2 CDH13	3.25e-05	184	146	6	76caad53d55fff5acca27bf190a6de7b27437d9f
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP2 PREX2 GIMAP8 USHBP1 PLXNA2 CDH13	3.25e-05	184	146	6	1fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP2 PREX2 GIMAP8 USHBP1 PLXNA2 CDH13	3.25e-05	184	146	6	2467207aaea307873ab286f89cfc7668a227a694
ToppCell	COPD-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	RARRES1 C4A C4B PRKD1 LONRF2 RSPO1	3.35e-05	185	146	6	23579988036fc1925992c31919750f9b3fe9f790
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MECOM RGS11 PREX2 TFPI GIMAP8 PLXNA2	3.35e-05	185	146	6	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	GBP2 CPLX4 IFIT3 HELB TRANK1 SPATS2L	3.67e-05	188	146	6	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	COPD-Epithelial-Mesothelial\|COPD / Disease state, Lineage and Cell class	RARRES1 C4A C4B PRKD1 LONRF2 RSPO1	3.78e-05	189	146	6	79bb2593ad5d17f94b17972884241f03a0f43770
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 AFF3 PREX2 FZD4 CADPS2 CDH13	3.78e-05	189	146	6	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MECOM RGS11 LRP1B RYR3 IVNS1ABP PRKD1	3.78e-05	189	146	6	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNE1 MECOM PREX2 CADPS2 PLXNA2 CDH13	3.78e-05	189	146	6	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM GBP2 PREX2 USHBP1 PLXNA2 CDH13	3.78e-05	189	146	6	25781edbd08c6e413740b796ecc8ba1934bd3aa5
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MECOM PREX2 FZD4 USHBP1 CADPS2 PLXNA2	3.89e-05	190	146	6	06bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 MECOM IVNS1ABP PRKD1 PRKCQ HYDIN	3.89e-05	190	146	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SYNE1 AFF3 FZD4 GIMAP8 CADPS2 CDH13	3.89e-05	190	146	6	0e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	AFF3 MECOM PREX2 FZD4 CADPS2 PLXNA2	3.89e-05	190	146	6	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	Control-Endothelial-VE_Capillary_B\|Control / Disease state, Lineage and Cell class	SYNE1 AFF3 PREX2 TFPI GIMAP8 CADPS2	4.01e-05	191	146	6	322237793a1278bafb14e63cab688b353e352dcc
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MECOM PREX2 GIMAP8 USHBP1 PLS3 CDH13	4.01e-05	191	146	6	04c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MECOM GTF2IRD1 LRP1B IVNS1ABP PRKD1 PRKCQ	4.01e-05	191	146	6	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MECOM PREX2 GIMAP8 USHBP1 PLS3 CDH13	4.01e-05	191	146	6	db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX SYNE1 IVNS1ABP ALB HYDIN TOP2B	4.13e-05	192	146	6	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 AFF3 MECOM TFPI PRKD1 CADPS2	4.25e-05	193	146	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MECOM PREX2 FZD4 RHOBTB1 USHBP1 PLXNA2	4.25e-05	193	146	6	3f8280ef849d95b2fcea5e6824b95a07febc96d0
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MECOM PREX2 GIMAP8 USHBP1 PLS3 CDH13	4.25e-05	193	146	6	3a9fe4e709c09ec787c71bdd6b58a71c419896de
ToppCell	IPF-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	AFF3 PREX2 TFPI FZD4 GIMAP8 CADPS2	4.25e-05	193	146	6	d7750a7575ef257963b7f1c64fa67c52dbff797b
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SYNE1 AFF3 TFPI FZD4 CADPS2 PLXNA2	4.25e-05	193	146	6	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNE1 AFF3 MECOM TFPI PRKD1 CADPS2	4.25e-05	193	146	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AFF3 PREX2 TFPI FZD4 GIMAP8 CADPS2	4.25e-05	193	146	6	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	SYNE1 MECOM PREX2 GIMAP8 CADPS2 PLXNA2	4.25e-05	193	146	6	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO NPEPPS MECOM GTF2IRD1 LRP1B CADPS2	4.37e-05	194	146	6	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	SYNE1 MECOM PREX2 PRKD1 CADPS2 PLXNA2	4.37e-05	194	146	6	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO NPEPPS MECOM GTF2IRD1 LRP1B CADPS2	4.37e-05	194	146	6	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	COPD-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	AFF3 PREX2 TFPI FZD4 GIMAP8 CADPS2	4.37e-05	194	146	6	68705a6eca947c5b42b943d5224a7aef2a744007
ToppCell	IPF-Endothelial-VE_Capillary_B\|IPF / Disease state, Lineage and Cell class	AFF3 PREX2 TFPI FZD4 GIMAP8 CADPS2	4.37e-05	194	146	6	169a304d5c13f08c39fad4116f093bc4a0765e9d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SYNE1 AFF3 MECOM PRKD1 PRKCQ CADPS2	4.37e-05	194	146	6	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	COPD-Endothelial-VE_Capillary_B\|COPD / Disease state, Lineage and Cell class	AFF3 PREX2 TFPI FZD4 GIMAP8 CADPS2	4.37e-05	194	146	6	18b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	SYNE1 MECOM PREX2 CADPS2 PLXNA2 CDH13	4.50e-05	195	146	6	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	MECOM GTF2IRD1 LRP1B IVNS1ABP PRKD1 PRKCQ	4.63e-05	196	146	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 PREX2 TLNRD1 GIMAP8 USHBP1 CDH13	4.63e-05	196	146	6	65d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX CLSTN1 IVNS1ABP PLS3 TOP2B CDH13	4.90e-05	198	146	6	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	Mild-CD8+_T_activated\|Mild / Disease group and Cell class	GBP2 IFIT3 HELB TRANK1 SPATS2L GZMH	4.90e-05	198	146	6	ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TRIO AFF3 MECOM NF1 PRKD1 CADPS2	4.90e-05	198	146	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	CV-Mild-1\|CV / Virus stimulation, Condition and Cluster	GBP2 IFIT3 HELB TRANK1 SPATS2L GIMAP8	4.90e-05	198	146	6	4b078714c49e7befb7b113d72485e712236d35fa
ToppCell	Skin-Endothelial\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	IFIT3 PREX2 FZD4 GIMAP8 USHBP1 CADPS2	5.03e-05	199	146	6	6b3ef5d8f87cdfe5401d05f19339ddfcd9cda476
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	RARRES1 ATRX RPS3A MBD1 SPATS2L NIPBL	5.03e-05	199	146	6	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATRX SYNE1 IFIT3 CCNH TRANK1 GZMH	5.18e-05	200	146	6	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SYNE1 IFIT3 IVNS1ABP TRANK1 GZMH NBPF10	5.18e-05	200	146	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Slco2a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SDK2 NSUN7 RYR3 IVNS1ABP CADPS2	7.73e-05	133	146	5	9d7a08170d38ae9b2ff10a0fa505aeb3aae2824d
ToppCell	Pericytes-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	ZNF845 PLCD3 HEATR6 MTR CDH13	1.36e-04	150	146	5	dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 PREX2 TLNRD1 GIMAP8 CDH13	1.79e-04	159	146	5	d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 LRP1B RYR3 FSHR HYDIN	1.84e-04	160	146	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 LRP1B RYR3 FSHR HYDIN	1.84e-04	160	146	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MECOM GBP2 DDC GIMAP8 USHBP1	1.89e-04	161	146	5	a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DAPK3 LRP1B RYR3 IGSF9B CDH13	2.01e-04	163	146	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D231\|Adult / Lineage, Cell type, age group and donor	RARRES1 RGS11 KCNB2 AR RSPO1	2.06e-04	164	146	5	3d8ff70fe5582d1fb56b338be8b76fa1428b3657
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP3 NSUN7 SPATS2L IGSF9B CDH13	2.12e-04	165	146	5	1703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCell	Control-Epithelial-Mesothelial\|World / Disease state, Lineage and Cell class	RARRES1 C4A C4B PRKD1 RSPO1	2.18e-04	166	146	5	32ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCell	normal_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	TLR7 IFIT3 GIMAP8 NBPF9 CADPS2	2.24e-04	167	146	5	820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 PREX2 FZD4 GIMAP8 CDH13	2.37e-04	169	146	5	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B RYR3 TRANK1 C4B HYDIN	2.37e-04	169	146	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MECOM CDC42BPB PREX2 ZBTB14 IVNS1ABP	2.44e-04	170	146	5	55fe16d98ea284d05fb899888e4569c685644c7b
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SDK2 AR PLCD3 FOXI2 PRKD1	2.44e-04	170	146	5	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122\|Adult / Lineage, Cell type, age group and donor	SYNE1 AFF3 FZD4 PLXNA2 CDH13	2.50e-04	171	146	5	bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNB2 NBPF19 RHOBTB1 FSHR CADPS2	2.64e-04	173	146	5	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNB2 RYR3 NBPF19 RHOBTB1 CADPS2	2.71e-04	174	146	5	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM PREX2 NSUN7 GIMAP8 USHBP1	2.71e-04	174	146	5	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM PREX2 NSUN7 GIMAP8 USHBP1	2.71e-04	174	146	5	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	10x5'-GI_small-bowel-Mast\|GI_small-bowel / Manually curated celltypes from each tissue	RARRES1 ENTHD1 LRP1B GFI1B WSCD2	2.71e-04	174	146	5	e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCell	10x5'-GI_small-bowel-Mast-Mast_cells\|GI_small-bowel / Manually curated celltypes from each tissue	RARRES1 ENTHD1 LRP1B GFI1B WSCD2	2.71e-04	174	146	5	05525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MECOM PREX2 NSUN7 GIMAP8 USHBP1	2.71e-04	174	146	5	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RGS11 KCNB2 DDC KCNJ11 LONRF2	2.79e-04	175	146	5	9941c35601134d88d1b3249c81f8b43a8fc61610
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPS3A DDC GGT1 GIMAP8 PRKCQ	2.79e-04	175	146	5	c38525583962c0e14130f4c98de912d8747bc4cb
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP2 IFIT3 PREX2 USHBP1 PLXNA2	2.94e-04	177	146	5	ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP2 IFIT3 PREX2 USHBP1 PLXNA2	2.94e-04	177	146	5	f471f7747d6e8db7546899019af9508f48a14f89
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP2 IFIT3 PREX2 USHBP1 PLXNA2	2.94e-04	177	146	5	cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXL13 ZBTB14 GFI1B PRKCQ RSPO1	3.01e-04	178	146	5	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX SYNE1 GBP2 IFIT3 PREX2	3.01e-04	178	146	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNB2 ITPK1 FSHR IGSF9B CADPS2	3.01e-04	178	146	5	731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNB2 NBPF19 RHOBTB1 FSHR CADPS2	3.09e-04	179	146	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASS4 FBXL13 SYNE1 GFI1B PRKCQ	3.17e-04	180	146	5	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CASS4 FBXL13 SYNE1 GFI1B PRKCQ	3.17e-04	180	146	5	4e9e8cde2919610c4ac0025b1c9819808048bc1d
Drug	tallimustine	PMS2 ERCC2 ERCC6 HSPA4 TOP2B	6.58e-07	27	143	5	CID000065924
Drug	HMS3267E16	RNGTT CASP3 AR RYR3 FSHR TCFL5	2.54e-06	62	143	6	CID000003668
Drug	rosiglitazone; Up 200; 10uM; HL60; HT_HG-U133A	TRIO TUBG2 TSHR SSTR5 CDC42BPB DDC ITPK1 FZD4 PRKCQ	4.63e-06	198	143	9	6192_UP
Disease	urinary bladder cancer (is_implicated_in)	PMS2 ERCC2 RASSF1 MTR CDH13	2.65e-05	76	135	5	DOID:11054 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_implicated_in)	ERCC2 ERCC6 CASP3 LRP1B RASSF1 CDH13	4.48e-05	139	135	6	DOID:3908 (is_implicated_in)
Disease	systemic lupus erythematosus (implicated_via_orthology)	TLR7 C4A C4B LYN	4.50e-05	43	135	4	DOID:9074 (implicated_via_orthology)
Disease	arthrogryposis multiplex congenita (is_implicated_in)	MYH8 SYNE1	1.24e-04	4	135	2	DOID:0080954 (is_implicated_in)
Disease	Cerebrooculofacioskeletal Syndrome 1	ERCC2 ERCC6	1.24e-04	4	135	2	C0220722
Disease	Drug habituation	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0013170
Disease	Drug abuse	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0013146
Disease	Prescription Drug Abuse	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C4316881
Disease	Substance-Related Disorders	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0236969
Disease	Drug Use Disorders	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0013222
Disease	Drug Dependence	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C1510472
Disease	Substance Dependence	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0038580
Disease	Substance Use Disorders	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0038586
Disease	Organic Mental Disorders, Substance-Induced	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.91e-04	115	135	5	C0029231
Disease	Substance abuse problem	SYNE1 AFF3 ZNF606 CADPS2 CDH13	1.99e-04	116	135	5	C0740858
Disease	extraversion	WSCD2 MTMR9	3.08e-04	6	135	2	EFO_0004317
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC2 ERCC6	3.08e-04	6	135	2	DOID:2962 (implicated_via_orthology)
Disease	bipolar disorder (is_implicated_in)	SYNE1 SSTR5 DDC	3.14e-04	29	135	3	DOID:3312 (is_implicated_in)
Disease	stomach cancer (is_implicated_in)	ERCC2 ERCC6 CASP3 LRP1B	3.39e-04	72	135	4	DOID:10534 (is_implicated_in)
Disease	Parkinson's disease (biomarker_via_orthology)	GRK6 DDC HSPA4	3.47e-04	30	135	3	DOID:14330 (biomarker_via_orthology)
Disease	Colorectal Carcinoma	PMS2 ERCC2 ERCC6 SYNE1 KCNB2 PREX2 FZD4 GFI1B NF1 PRKD1 LONRF2	3.97e-04	702	135	11	C0009402
Disease	Cerebral ventriculomegaly	IFT122 HYDIN	4.30e-04	7	135	2	C1531647
Disease	Hydrocephalus Ex-Vacuo	IFT122 HYDIN	4.30e-04	7	135	2	C0270720
Disease	Communicating Hydrocephalus	IFT122 HYDIN	4.30e-04	7	135	2	C0009451
Disease	Fetal Cerebral Ventriculomegaly	IFT122 HYDIN	4.30e-04	7	135	2	C2936718
Disease	leukemia (is_marker_for)	TFPI ALB	4.30e-04	7	135	2	DOID:1240 (is_marker_for)
Disease	Post-Traumatic Hydrocephalus	IFT122 HYDIN	4.30e-04	7	135	2	C0477432
Disease	Obstructive Hydrocephalus	IFT122 HYDIN	4.30e-04	7	135	2	C0549423
Disease	peptic ulcer disease	GRK6 MECOM GGT1	4.62e-04	33	135	3	MONDO_0004247
Disease	Complement deficiency disease	CFHR5 C4A C4B	4.62e-04	33	135	3	C0272242
Disease	Parkinsonism (biomarker_via_orthology)	CASP3 KCNJ11 LYN	5.05e-04	34	135	3	DOID:0080855 (biomarker_via_orthology)
Disease	Prostatic Neoplasms	ERCC2 MBD1 LRP1B AR GGT1 IVNS1ABP CCNH ARID2 ZNF160 CDH13	5.58e-04	616	135	10	C0033578
Disease	Malignant neoplasm of prostate	ERCC2 MBD1 LRP1B AR GGT1 IVNS1ABP CCNH ARID2 ZNF160 CDH13	5.58e-04	616	135	10	C0376358
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	TRIO CDH13	5.71e-04	8	135	2	EFO_0005400, MONDO_0009354
Disease	Abdominal Cryptorchidism	ATRX CASP3	5.71e-04	8	135	2	C1563730
Disease	Inguinal Cryptorchidism	ATRX CASP3	5.71e-04	8	135	2	C1563731
Disease	Williams Syndrome	FKBP6 GTF2IRD1	5.71e-04	8	135	2	C0175702
Disease	Congenital Hydrocephalus	IFT122 HYDIN	5.71e-04	8	135	2	C0020256
Disease	Bilateral Cryptorchidism	ATRX CASP3	5.71e-04	8	135	2	C0431663
Disease	Unilateral Cryptorchidism	ATRX CASP3	5.71e-04	8	135	2	C0431664
Disease	Aqueductal Stenosis	IFT122 HYDIN	5.71e-04	8	135	2	C2936786
Disease	lung squamous cell carcinoma (is_marker_for)	ERCC6 ATRX PREX2	5.99e-04	36	135	3	DOID:3907 (is_marker_for)
Disease	Hydrocephalus	IFT122 HYDIN	7.32e-04	9	135	2	C0020255
Disease	Retinal Pigment Epithelial Detachment	CASP3 PRKCQ	7.32e-04	9	135	2	C0339546
Disease	Graves' disease (is_implicated_in)	TSHR C4A C4B	7.59e-04	39	135	3	DOID:12361 (is_implicated_in)
Disease	Craniofacial Abnormalities	ERCC6 ATRX GTF2IRD1 FZD4 NIPBL	7.73e-04	156	135	5	C0376634
Disease	Cryptorchidism	ATRX CASP3	9.13e-04	10	135	2	C0010417
Disease	high grade glioma (is_implicated_in)	ERCC2 ATRX NF1	9.44e-04	42	135	3	DOID:3070 (is_implicated_in)
Disease	autistic disorder (is_implicated_in)	NF1 MTR C4B	9.44e-04	42	135	3	DOID:12849 (is_implicated_in)
Disease	Adenocarcinoma of large intestine	PMS2 DAPK3 CDC42BPB PRKCQ	1.01e-03	96	135	4	C1319315
Disease	Retinal Detachment	CASP3 PRKCQ	1.11e-03	11	135	2	C0035305
Disease	Prostatic Intraepithelial Neoplasias	AR TOP2B	1.11e-03	11	135	2	C0282612
Disease	Occupational Diseases	ERCC2 ALB	1.11e-03	11	135	2	C0028797
Disease	ovarian serous carcinoma	PLEKHM1 USHBP1 RSPO1	1.23e-03	46	135	3	EFO_1001516
Disease	Primary Ciliary Dyskinesia	SPEF2 IFT122 HYDIN	1.31e-03	47	135	3	C4551720
Disease	endometrial carcinoma (is_implicated_in)	RASSF1 CDH13	1.33e-03	12	135	2	DOID:2871 (is_implicated_in)
Disease	Malignant neoplasm of breast	ERCC6 SYNE1 MECOM CFHR5 AR CCNH NF1 GUCY2F MTR OXSM NIPBL PLS3 ZNF646	1.33e-03	1074	135	13	C0006142
Disease	bipolar disorder	SYNE1 MRPL33 GFI1B TRANK1 SPATS2L WSCD2 PRKD1 IGSF9B CDH13	1.39e-03	577	135	9	MONDO_0004985
Disease	Male sterility	AR NSUN7 MTR	1.39e-03	48	135	3	C0917731
Disease	Male infertility	AR NSUN7 MTR	1.39e-03	48	135	3	C0021364
Disease	Subfertility, Male	AR NSUN7 MTR	1.39e-03	48	135	3	C0848676
Disease	hepatocellular carcinoma (is_implicated_in)	ERCC2 LRP1B RYR3 ARID2 ALB	1.50e-03	181	135	5	DOID:684 (is_implicated_in)
Disease	Glioblastoma Multiforme	ATRX CCNH NF1 GUCY2F	1.72e-03	111	135	4	C1621958
Disease	gamma-glutamylglutamate measurement	GGT1 PRKD1	1.82e-03	14	135	2	EFO_0021137
Disease	leukemia	AR FANCD2 NF1	2.07e-03	55	135	3	C0023418
Disease	health study participation	AFF3 LRP1B PLCD3 PLXNA2 ZNF646	2.07e-03	195	135	5	EFO_0010130
Disease	prostate cancer (is_implicated_in)	ERCC2 AR RASSF1 CDH13	2.08e-03	117	135	4	DOID:10283 (is_implicated_in)
Disease	ovarian cancer (is_implicated_in)	PMS2 RASSF1 CDH13	2.17e-03	56	135	3	DOID:2394 (is_implicated_in)
Disease	Diabetic Angiopathies	CASP3 ALB	2.39e-03	16	135	2	C0011875
Disease	Microangiopathy, Diabetic	CASP3 ALB	2.39e-03	16	135	2	C0025945
Disease	Pheochromocytoma, Extra-Adrenal	DDC NF1	2.39e-03	16	135	2	C1257877
Disease	MAJOR AFFECTIVE DISORDER 2	DDC FZD4	2.70e-03	17	135	2	C1839839
Disease	household income	AFF3 ENTHD1 LRP1B SPATS2L PRKD1 LONRF2	2.82e-03	304	135	6	EFO_0009695
Disease	Myeloid Leukemia	MECOM TOP2B	3.03e-03	18	135	2	C0023470
Disease	Leukemia, Monocytic, Chronic	MECOM TOP2B	3.03e-03	18	135	2	C0023466
Disease	Pheochromocytoma	DDC NF1	3.38e-03	19	135	2	C0031511
Disease	ovarian neoplasm	PMS2 ERCC6 MECOM CCNH	3.40e-03	134	135	4	C0919267
Disease	MYELODYSPLASTIC SYNDROME	ATRX MECOM FANCD2	3.62e-03	67	135	3	C3463824
Disease	Parkinson disease	PLEKHM1 HEATR6 WSCD2 IGSF9B CDH13 ZNF646	3.68e-03	321	135	6	MONDO_0005180
Disease	Malignant neoplasm of ovary	PMS2 ERCC6 MECOM CCNH	3.68e-03	137	135	4	C1140680
Disease	skin pigmentation	DEF8 CFHR5 CADPS2	3.94e-03	69	135	3	EFO_0003784
Disease	renal cell carcinoma (is_implicated_in)	RASSF1 C4A C4B	3.94e-03	69	135	3	DOID:4450 (is_implicated_in)
Disease	Infiltrating duct carcinoma of female breast	GRK6 CDC42BPB	4.12e-03	21	135	2	C3165106
Disease	gastric ulcer	MECOM GGT1	4.12e-03	21	135	2	EFO_0009454
Disease	Arthrogryposis	ERCC6 VIPAS39	4.12e-03	21	135	2	C0003886
Disease	cholangiocarcinoma (is_implicated_in)	PREX2 ALB	4.52e-03	22	135	2	DOID:4947 (is_implicated_in)
Disease	Leber Congenital Amaurosis	LCA5 IQCB1	4.52e-03	22	135	2	C0339527

Protein segments in the cluster

Peptide	Gene	Start	Entry
RGSIEKLKCFNRLLS	USHBP1	301	Q8N6Y0
KLKCFNRLLSAVLQG	USHBP1	306	Q8N6Y0
GSNGHRDCKRQKLVF	AFF3	956	P51826
LSFLICNKGRNAIRV	FAM223B	26	A6NKX1
SKNCKLFAASKNVRR	CDY2A	106	Q9Y6F7
RLKCASLQKFGERAF	ALB	221	P02768
ANRKFRCKAVANGKV	CCNH	26	P51946
IANGRLLFKRNCEKE	CASS4	581	Q9NQ75
FCIGRDIRKKDINNI	COPS7B	156	Q9H9Q2
CQFAESLRKKSRDKG	C4B	736	P0C0L5
CDLPVRAAKFVARKN	COPB2	56	P35606
AFVQFLQEKSRKRCG	GZMH	36	P20718
TRLFCADKNERIGKS	AGO1	711	Q9UL18
GNVKLLAANRTCLRF	ARID2	301	Q68CP9
IATKNREEKAACLRN	AKAP11	821	Q9UKA4
LDRKFKLICSELNGR	CLSTN1	786	O94985
LNLTFSDCKGNDKLR	CDH13	51	P55290
LGLVCFRLKGSNKVN	DDC	406	P20711
LKKITNFFRGDRCRS	CASP3	136	P42574
LSFERKKQGCNKRAA	ERCC6	281	Q03468
SEQLRRDCGKNTANK	RANBP9	631	Q96S59
VRKGLQCARLSADCK	RASSF1	76	Q9NS23
AKQRSKGDRLVIACQ	RGS11	171	O94810
RCFGQQTNLDRHLKK	MECOM	976	Q03112
LSFERKKQGCNKRAA	ERCC6	281	P0DP91
LCQQLRSKRKFFGTV	OXSM	21	Q9NWU1
FGRLHNKRNVCKAGL	ENTHD1	191	Q8IYW4
RSLKNNSLEGRCKAL	OR4C12	221	Q96R67
LKGLFRQGLQCKDCR	PRKD1	291	Q15139
SLAERCRKNNGKTEI	PRKCQ	91	Q04759
KLNFQAFAELCRKRG	ITPK1	21	Q13572
EKRLQCLSFSGVKER	IFT122	451	Q9HBG6
KRQANSGLICPEFKR	LRP1B	3956	Q9NZR2
SVCAFNRGKLKVLAT	HSPA4	211	P34932
FIDRCTAASQGQKRK	RNGTT	561	O60942
KLNALRKSGQFCDVR	IVNS1ABP	21	Q9Y6Y0
LRRCDQVQFEKCGKR	MST1L	461	Q2TV78
TFLGNNESERCKLKL	MTMR9	436	Q96QG7
KAKQLKAEAGRSCQR	HHLA3	76	Q9XRX5
CELCTKGFQRKVDLR	GFI1B	306	Q5VTD9
RRNDKQLCLTASKFV	CWC22	246	Q9HCG8
RHNLSLNDCFKKVPR	FOXI2	151	Q6ZQN5
RRARFVSKKGNCNVA	KCNJ11	31	Q14654
KTLCKDCRAQRIAFN	MBD1	151	Q9UIS9
ERSNAACAALDKKQR	MYH8	1436	P13535
KTFRKAINRKEGICA	PLS3	91	P13797
AQRESCGLCLKADRK	PLXNA2	806	O75051
LLFTRKGKDCNLGNL	MINDY4B	161	A8MYZ0
AGLLQRFCSQLVKRQ	NAT16	136	Q8N8M0
LSFLICNKGRNAIRV	FAM223A	26	Q8IWN6
RTAQNFLSIFLKKCG	NIPBL	1536	Q6KC79
SGQFAIVRKCRQKGT	DAPK3	21	O43293
CKNFKVRIRSAAALS	HEATR6	1011	Q6AI08
AFLSGLAQRVCIQRK	ERCC2	356	P18074
KELALRKNAACQSDF	LCA5	311	Q86VQ0
KLGAQLEARRDDFCK	GBP2	381	P32456
LEARRDDFCKQNSKA	GBP2	386	P32456
CKDKLSELLASRNFN	LONRF2	486	Q1L5Z9
RAAEGKQKYLCASRN	AR	586	P10275
LKRNSGTCLFVAVKR	CDC42BPB	1336	Q9Y5S2
LIIDQKNAKALFRCG	FKBP6	246	O75344
KNAKALFRCGQACLL	FKBP6	251	O75344
KCSNRLVNSGKVKRE	FZD4	506	Q9ULV1
HNAFCKKCILRNLGR	ATRX	236	P46100
AAFTQKKAERACLRV	CPLX4	61	Q7Z7G2
LLGATFNCLNKRLAK	CLCN6	346	P51797
CNVLVGRQAKARFKI	HYDIN	3371	Q4G0P3
KTCSRRVKINVGGLN	KCNB2	31	Q92953
KRNNCGKALDIARQA	GCDH	371	Q92947
RFCLDSAKQTRQKVA	FAM193B	871	Q96PV7
LKSRNCVVDGRFVLK	GUCY2F	671	P51841
NSDNKALRRIFKKCG	GIMAP8	581	Q8ND71
QLKCGRNERAKVCFE	IFIT3	146	O14879
KEQFKLCINRSHRGF	CC2D1A	711	Q6P1N0
FLRNDTLLCNGKFHK	CADPS2	911	Q86UW7
GDRDCVLQKSRDLKF	COQ8B	411	Q96D53
ALSACKLRKIRFEGN	FBXL13	396	Q8NEE6
LKFSCRKNLIRVGSD	CFHR5	171	Q9BXR6
YQKQADGLCRRLEKA	LYN	211	P07948
KCARLSLRKQSLFQE	DEF8	491	Q6ZN54
VTLQRAALKFLAKCR	IQCB1	421	Q15051
KNFRRDFFILLSKCG	FSHR	631	P23945
NCFGIAKLRKILEAS	GTF2IRD1	616	Q9UHL9
DKRKACGRQLTQNFL	GRK6	96	P43250
RRLSVKNSFCRKNGL	SDK2	1996	Q58EX2
DRLLRLSQKKFCAGG	NPEPPS	516	P55786
KNKRDFESNVRLCNG	HELB	821	Q8NG08
CQFAESLRKKSRDKG	C4A	736	P0C0L4
NKEKIASLARQFLCR	FANCD2	1151	Q9BXW9
SILRINCAEGRKKAF	OR13D1	256	Q8NGV5
KTGITLKSCRRQFDN	FIBP	126	O43427
SLEALKCFRIRNNEK	PLEKHM1	706	Q9Y4G2
LTGCNRNLTEVERKK	SPEF2	741	Q9C093
GQRKVLFTCFKRNDK	TOP2B	746	Q02880
LGKAARFSCDIEQLK	SPATS2L	331	Q9NUQ6
CLSDLVGQRRKYLNK	SYNE1	4436	Q8NF91
FRNLKEKCFLTQLAG	NBPF9	306	P0DPF3
FRNLKEKCFLTQLSG	NBPF10	306	Q6P3W6
RNLKEKCFLTQLAGF	NBPF15	36	Q8N660
RNLKEKCFLTQLAGF	NBPF19	36	A0A087WUL8
RLFCVGFTKKRNNQI	RPS3A	136	P61247
FSKLCLNIRLAVKEG	TACO1	81	Q9BSH4
LNSFKIKLAAALARC	NSUN7	161	Q8NE18
CRSKKLKAQAIFLGN	NEPRO	381	Q6NW34
ERCNVAGSRKFAKLI	MTR	376	Q99707
NRACERALQYKLGDK	PITRM1	31	Q5JRX3
KKQQLCGFRRGSEER	RSPO1	161	Q2MKA7
LEKGCDRSIVNKSRQ	NUDT12	66	Q9BQG2
CEKEKQSRDFQGRIL	RHOBTB1	311	O94844
FRQSFQKVLCLRKGS	SSTR5	311	P35346
NECGKVFNRKAKLAR	ZNF845	946	Q96IR2
RCKRAQAFISTQGLK	SPG11	2031	Q96JI7
GRAVRKLQAQCQFLS	PITPNM1	1146	O00562
ARGCFLNAKRNKTPV	PRAMEF6	121	Q5VXH4
NLNADFRFCVKAKRK	TAS2R7	151	Q9NYW3
GIRFLDKLCSQKRDV	ZBTB14	116	O43829
KQCGKAFRSASQLRV	ZNF700	421	Q9H0M5
FSLLTQRRKANSCGK	ZNF160	241	Q9HCG1
NECGKSFGRKSQLIL	ZNF157	221	P51786
TGFCFNTKRNRLREK	MRPL33	26	O75394
STLAACFVNKQRKRK	IGSF9B	741	Q9UPX0
ARCLTIAFKGRRKNL	PLCD3	136	Q8N3E9
CASVKRNVTDFLKRA	RYR3	4146	Q15413
SECGKAFRLRKQLAS	ZNF646	1261	O15015
CRNKFLLKNKQADRS	NF1	606	P21359
RDRFSREQFKLGVKC	TLNRD1	206	Q9H1K6
EKGERNSKRVCFNVA	PREX2	1076	Q70Z35
KGKVCSLERFRSLQD	VIPAS39	166	Q9H9C1
KECGKAFSLLTQLAR	ZNF780B	476	Q9Y6R6
QECLRACKKGFIQRI	TFPI	261	P10646
QKSKFLQLRKRLCGS	TLR7	996	Q9NYK1
DVCGKVFNRKRNLVC	ZNF813	246	Q6ZN06
RKFRAKICPGENQAA	PMS2	646	P54278
KECGKAFRVRQQLTL	ZFP82	341	Q8N141
KECRKAFRLNSSLIQ	ZFP82	481	Q8N141
EQNKRPCRKFLLTGQ	ZMAT5	51	Q9UDW3
SCQQFDKLRKRDAFL	TUBG2	391	Q9NRH3
RCQIHFGDNRKLKLS	TRMT12	286	Q53H54
RLLCVESQKDGNFKR	WSCD2	506	Q2TBF2
FLRTLEQCRTKFKGL	ZSCAN29	291	Q8IWY8
RAGNFKKADVDRTQC	TRANK1	2711	O15050
GRLGKCSARVFFKNQ	RARRES1	121	P49788
GEAALCKQALKRNRS	TCFL5	331	Q9UL49
RQCGKTFRNQSILKT	ZNF317	421	Q96PQ6
QKEAFLKACTLARRN	TRIO	1066	O75962
DKCGKVFRNRSALTK	ZNF606	431	Q8WXB4
QKDGIIFALKRNGRC	ZRANB3	41	Q5FWF4
KECGKAFRSASQLRI	ZNF439	441	Q8NDP4
ILLSKFGICKRQAQA	TSHR	691	P16473
DAKQCSKIGRDALRD	GGT1	46	P19440
FENNKLLRREKCSAI	MORN4	116	Q8NDC4
RKVGALESKLAACRN	NDEL1	261	Q9GZM8
LESKLAACRNFAKDQ	NDEL1	266	Q9GZM8