Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.81e-1326908GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

7.93e-1152908GO:0005272
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

3.22e-0914905GO:0031402
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

1.01e-0726905GO:0031420
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.05e-06171908GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

2.44e-05343909GO:0005261
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A SCN10A

5.75e-0517903GO:0099508
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

2.25e-04459909GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

2.48e-04465909GO:0046873
GeneOntologyMolecularFunctionchannel activity

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

5.99e-04525909GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.07e-04526909GO:0022803
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1B TPCN2 SCN1A SCN2A SCN10A

1.40e-03182905GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1B TPCN2 SCN1A SCN2A SCN10A

1.47e-03184905GO:0022832
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.94e-1036917GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.04e-0862917GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.16e-0863917GO:0019228
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.13e-0787917GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.79e-0793917GO:0086003
GeneOntologyBiologicalProcessactin filament-based movement

MYO1C SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.85e-07153918GO:0030048
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.40e-07112917GO:0019226
GeneOntologyBiologicalProcessmembrane depolarization

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.08e-06121917GO:0051899
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.50e-06127917GO:0070252
GeneOntologyBiologicalProcesssodium ion transport

DRD2 TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.53e-06275919GO:0006814
GeneOntologyBiologicalProcesssodium ion transmembrane transport

TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.88e-06208918GO:0035725
GeneOntologyBiologicalProcessheart contraction

CACNA1B DRD2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.76e-06298919GO:0060047
GeneOntologyBiologicalProcessheart process

CACNA1B DRD2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

9.04e-06309919GO:0003015
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

9.20e-06167917GO:0060048
GeneOntologyBiologicalProcessaction potential

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.05e-05201917GO:0001508
GeneOntologyBiologicalProcessstriated muscle contraction

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

4.96e-05217917GO:0006941
GeneOntologyBiologicalProcessmuscle contraction

DRD2 TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.84e-05400919GO:0006936
GeneOntologyBiologicalProcessresponse to pain

CACNA1B SCN3A SCN9A SCN10A

7.56e-0551914GO:0048265
GeneOntologyBiologicalProcesspositive regulation of renal sodium excretion

NPR1 DRD2

1.15e-044912GO:0035815
GeneOntologyBiologicalProcessblood circulation

CACNA1B GPR4 NPR1 DRD2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.31e-046489111GO:0008015
GeneOntologyBiologicalProcessactin filament-based process

MYO3A KISS1R MYO1C SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A OBSCN SCN10A PDXP OBSL1

1.78e-049129113GO:0030029
GeneOntologyBiologicalProcesspositive regulation of DNA damage checkpoint

TTI2 TTI1

1.91e-045912GO:2000003
GeneOntologyBiologicalProcessbehavioral response to pain

SCN3A SCN9A SCN10A

3.76e-0432913GO:0048266
GeneOntologyBiologicalProcesscirculatory system process

CACNA1B GPR4 NPR1 DRD2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.78e-047339111GO:0003013
GeneOntologyBiologicalProcessnegative regulation of toll-like receptor 2 signaling pathway

MFHAS1 NOD2

3.99e-047912GO:0034136
GeneOntologyBiologicalProcessregulation of renal sodium excretion

NPR1 DRD2

5.30e-048912GO:0035813
GeneOntologyBiologicalProcessnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

DRD2 SH2B3 NOP53 OBSCN

5.71e-0486914GO:0051898
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

4.76e-1317927GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.66e-1129927GO:0034706
GeneOntologyCellularComponentcation channel complex

CACNA1B SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

9.36e-06235928GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

4.35e-05378929GO:0034702
GeneOntologyCellularComponentTTT Hsp90 cochaperone complex

TTI2 TTI1

5.73e-053922GO:0110078
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

8.91e-0520923GO:0033268
GeneOntologyCellularComponentintercalated disc

SCN1A SCN2A OBSCN OBSL1

2.31e-0468924GO:0014704
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

2.77e-0429923GO:0043194
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

4.94e-04523929GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

7.08e-04550929GO:1990351
GeneOntologyCellularComponentcell-cell contact zone

SCN1A SCN2A OBSCN OBSL1

7.92e-0494924GO:0044291
GeneOntologyCellularComponentaxon

CACNA1B DRD2 NRTN SIGMAR1 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.83e-038919211GO:0030424
HumanPhenoImpulsivity

CACNA1B GLDC SCN1A SCN2A SCN3A SCN8A SCN9A TTI1 SRCAP DALRD3

6.00e-081493710HP:0100710
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A

4.03e-0616374HP:0011172
HumanPhenoTibial torsion

SCN1A SCN2A SCN9A TTI1

1.89e-0523374HP:0100694
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

1.93e-058373HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

1.93e-058373HP:0200048
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

2.67e-0525374HP:0006813
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

3.67e-0527374HP:0011171
HumanPhenoErythromelalgia

SH2B3 SCN9A SCN10A

4.09e-0510373HP:0032147
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

5.59e-0511373HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

7.42e-0512373HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

7.42e-0512373HP:0032898
HumanPhenoStatus epilepticus

CACNA1B SCN1A SCN2A SCN3A SCN8A SCN9A VPS51 DALRD3

9.06e-05207378HP:0002133
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A

9.35e-0534374HP:0011169
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

9.60e-0513373HP:0007058
HumanPhenoRigidity

CACNA1B SCN1A SCN2A SCN3A SCN8A SCN9A SMPD1 DALRD3

1.14e-04214378HP:0002063
HumanPhenoFacial tics

SCN1A SCN2A SCN9A

1.51e-0415373HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A

1.51e-0415373HP:0007207
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

1.85e-0416373HP:0025101
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A

2.17e-0442374HP:0002266
HumanPhenoMyoclonus

CACNA1B DRD2 GLDC SCN1A SCN2A SCN3A SCN8A SCN9A DALRD3 TOE1

2.18e-043713710HP:0001336
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

2.24e-0417373HP:0032663
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

2.24e-0417373HP:0011151
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A SCN8A SCN9A

2.63e-0481375HP:0020221
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A

2.67e-0418373HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

2.67e-0418373HP:0032860
HumanPhenoAbnormal hippocampus morphology

SCN1A SCN2A SCN9A VPS51

3.65e-0448374HP:0025100
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

3.69e-0420373HP:0032671
HumanPhenoEEG with abnormally slow frequencies

CACNA1B SCN1A SCN3A SCN8A DALRD3

3.87e-0488375HP:0011203
HumanPhenoAbnormal morphology of the limbic system

SCN1A SCN2A SCN9A VPS51

3.95e-0449374HP:0007343
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

4.29e-0421373HP:0004684
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A

4.94e-0422373HP:0020207
HumanPhenoEEG with multifocal slow activity

CACNA1B SCN3A SCN8A DALRD3

4.97e-0452374HP:0010844
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

5.06e-045372HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

5.06e-045372HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

5.06e-045372HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

5.06e-045372HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

5.06e-045372HP:0032906
HumanPhenoAllodynia

SCN9A SCN10A

5.06e-045372HP:0012533
HumanPhenoWeakness of the intrinsic hand muscles

FBXO38 SIGMAR1 SCN4A

6.43e-0424373HP:0009005
HumanPhenoPes valgus

SCN1A SCN2A SCN4A SCN9A

6.61e-0456374HP:0008081
HumanPhenoAbnormality of the calcaneus

SCN1A SCN2A SCN9A OBSL1

7.07e-0457374HP:0008364
HumanPhenoIntellectual disability, borderline

SCN3A SCN8A ALOXE3

7.27e-0425373HP:0006889
HumanPhenoNormal interictal EEG

SCN2A SCN8A

7.56e-046372HP:0002372
HumanPhenoAggressive behavior

CACNA1B GLDC SCN1A SCN2A SCN3A TTI2 SCN8A SCN9A TTI1 SRCAP DALRD3

7.62e-045163711HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

CACNA1B GLDC SCN1A SCN2A SCN3A TTI2 SCN8A SCN9A TTI1 SRCAP DALRD3

7.62e-045163711HP:0006919
HumanPhenoCompulsive behaviors

DRD2 SCN1A SCN2A SCN8A SCN9A SRCAP

8.48e-04158376HP:0000722
HumanPhenoLimited knee extension

SCN1A SCN2A SCN9A

9.15e-0427373HP:0003066
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A SCN9A

9.15e-0427373HP:0031475
HumanPhenoReduced tendon reflexes

CACNA1B FBXO38 SIGMAR1 GLDC SCN3A SCN4A SCN8A SCN9A OBSCN SCN10A SMPD1 DALRD3

9.37e-046173712HP:0001315
HumanPhenoFocal aware seizure

SCN1A SCN2A SCN9A

1.02e-0328373HP:0002349
HumanPhenoEyelid myoclonia seizure

SCN2A SCN8A

1.05e-037372HP:0032678
HumanPhenoGeneralized tonic seizure

SCN1A SCN2A SCN8A SCN9A

1.10e-0364374HP:0010818
HumanPhenoAthetosis

CACNA1B SCN1A SCN2A SCN8A SMPD1 TOE1

1.10e-03166376HP:0002305
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN2A SCN9A

1.13e-0329373HP:0032658
HumanPhenoLimb myoclonus

DRD2 SCN2A SCN8A

1.13e-0329373HP:0045084
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A

1.23e-0366374HP:0010841
HumanPhenoProgressive gait ataxia

SCN1A SCN2A SCN9A

1.25e-0330373HP:0007240
HumanPhenoProgressive ataxia

SCN1A SCN2A SCN9A

1.25e-0330373HP:0001329
MousePhenoimpaired behavioral response to alcohol

CACNA1B TAOK3 DRD2

1.80e-0510763MP:0009755
MousePhenoabnormal single cell response

CACNA1B DRD2 SCN9A SCN10A

3.72e-0535764MP:0003463
DomainNa_channel_asu

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.11e-1510917IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.11e-1510917IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.11e-1510917PF06512
DomainChannel_four-helix_dom

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

7.66e-1257919IPR027359
Domain-

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

7.66e-12579191.20.120.350
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A SCN9A

1.47e-116915PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN8A SCN9A

1.47e-116915IPR024583
DomainIQ_motif_EF-hand-BS

MYO3A MYO1C SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A OBSCN SCN10A

1.89e-11909110IPR000048
DomainIQ

MYO3A MYO1C SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A OBSCN SCN10A

2.63e-11939110PS50096
DomainIQ

MYO3A MYO1C SCN1A SCN3A SCN4A SCN8A SCN9A OBSCN SCN10A

6.00e-1171919PF00612
DomainIQ

MYO3A MYO1C SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A OBSCN

2.02e-1081919SM00015
DomainIon_trans_dom

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

4.41e-09114919IPR005821
DomainIon_trans

CACNA1B TPCN2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

4.41e-09114919PF00520
DomainEF-hand-dom_pair

CAPN12 CACNA1B SCN1A SCN3A SCN8A SCN9A RAB11FIP4

5.06e-04287917IPR011992
Domain-

FBXO38 PODNL1 MFHAS1 LINGO3 LGR6 NYX NOD2

9.78e-043219173.80.10.10
DomainL_dom-like

FBXO38 PODNL1 MFHAS1 LINGO3 LGR6 NYX NOD2

1.11e-03328917IPR032675
DomainLRRNT

PODNL1 LINGO3 LGR6 NYX

1.34e-0398914IPR000372
DomainLRRNT

PODNL1 LINGO3 LGR6 NYX

1.34e-0398914SM00013
DomainLRR_8

PODNL1 MFHAS1 LINGO3 LGR6 NYX

1.50e-03171915PF13855
DomainLeu-rich_rpt_typical-subtyp

PODNL1 MFHAS1 LINGO3 LGR6 NYX

1.74e-03177915IPR003591
DomainLRR_TYP

PODNL1 MFHAS1 LINGO3 LGR6 NYX

1.74e-03177915SM00369
DomainLeu-rich_rpt

PODNL1 MFHAS1 LINGO3 LGR6 NYX NOD2

2.10e-03271916IPR001611
DomainLRRNT

LINGO3 LGR6 NYX

2.20e-0353913PF01462
DomainFN3

RIMBP3 PTPRB OBSCN OBSL1 EPHA10

2.90e-03199915PS50853
DomainLRR

PODNL1 MFHAS1 LINGO3 LGR6 NOD2

3.02e-03201915PS51450
DomainFN3_dom

RIMBP3 PTPRB OBSCN OBSL1 EPHA10

3.57e-03209915IPR003961
DomainLRR_1

PODNL1 MFHAS1 LINGO3 LGR6 NYX

4.35e-03219915PF00560
Domain-

PITPNM2 STARD9

5.56e-03239123.30.530.20
DomainSTART-like_dom

PITPNM2 STARD9

5.56e-0323912IPR023393
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

5.43e-1131627M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

6.93e-1132627M27455
PathwayREACTOME_CARDIAC_CONDUCTION

NPR1 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

9.38e-08130628M27454
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

9.59e-07121627M872
PathwayREACTOME_MUSCLE_CONTRACTION

NPR1 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

2.80e-06203628M5485
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

6.42e-0628624M45519
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

NRTN SCN1A SCN2A SCN3A SCN4A CYP51A1 SCN8A SCN9A SCN10A EPHA10

1.87e-045756210M29853
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

DRD2 SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.94e-04367628M48346
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

2.78e-17993716382098
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A SCN10A

3.10e-16693623652591
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN8A SCN9A SCN10A

5.24e-131393615123669
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN4A SCN8A

1.53e-11993515746173
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

4.79e-11493417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

4.79e-11493435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

4.79e-11493429578003
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

2.39e-1059348812438
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN4A SCN8A

2.39e-10593417724025
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

1.85e-08393319284629
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

1.85e-08393312610651
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

1.85e-08393333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

1.85e-08393323859570
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN3A SCN9A SCN10A

1.85e-08393319699781
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

1.85e-08393318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

1.85e-08393317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

1.85e-08393332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

1.85e-08393328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

1.85e-08393317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

1.85e-08393314973256
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN8A

2.33e-081293430175250
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

DRD2 SCN1A SCN2A SCN3A

6.39e-08159349726281
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

7.39e-08493321156207
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN1A SCN9A SCN10A

7.39e-08493322260870
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

7.39e-08493335801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

7.39e-0849338974318
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1B SCN1A SCN3A SCN4A SCN8A SCN9A SCN10A

9.95e-0813993716985003
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

1.84e-0759331679748
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN8A SCN9A

1.84e-07593322875929
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

1.84e-07593324337656
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN8A SCN9A SCN10A

3.68e-07693316029194
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN3A SCN8A SCN10A

3.68e-07693323711479
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

6.43e-07793325818041
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN3A SCN9A SCN10A

6.43e-07793324440715
Pubmed

Significant determinants of mouse pain behaviour.

SCN3A SCN9A SCN10A

1.03e-06893325101983
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

THEM6 CNNM3 ATAD3B POM121 SIGMAR1 TTI2 CLPTM1 CYP51A1 PDXP OBSL1 SRP68 GALNT12 VPS51

1.37e-06942931331073040
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN3A SCN9A SCN10A

1.54e-0699338854872
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

4.00e-06129338169823
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

7.07e-06293229649454
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

7.07e-06293220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

7.07e-06293237901435
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

7.07e-06293218079277
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

7.07e-06293226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

7.07e-06293210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

7.07e-06293219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

7.07e-06293235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

7.07e-06293211245985
Pubmed

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

SCN9A SCN10A

7.07e-06293216111501
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

7.07e-06293215760941
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

7.07e-0629321317301
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

7.07e-06293223016767
Pubmed

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers.

DRD2 SIGMAR1

7.07e-06293223637801
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

7.07e-06293227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

7.07e-06293233096315
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

7.07e-06293224990319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

7.07e-06293225172946
Pubmed

Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel.

CACNA1B SIGMAR1

7.07e-06293228603497
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

7.07e-06293231439038
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

7.07e-06293217805013
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

7.07e-06293226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

7.07e-06293233411788
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

7.07e-06293231943325
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

7.07e-06293215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

7.07e-06293227690330
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

7.07e-06293227174182
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

7.07e-06293221377452
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

7.07e-06293218601978
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

7.07e-06293223965409
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

7.07e-06293219465131
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

7.07e-06293237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

7.07e-06293217881658
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

7.07e-06293230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

7.07e-06293223735284
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CCND3 PITPNM2 SH2B3 MFHAS1 SGSM2 NBEAL2 SCN8A OBSCN SNAPC4 SRCAP BIRC6 PKN3 NOD2

7.74e-061105931335748872
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

2.12e-05393228784306
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

2.12e-05393232185219
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

2.12e-05393232005694
Pubmed

The cell and molecular basis of mechanical, cold, and inflammatory pain.

SCN9A SCN10A

2.12e-05393218669863
Pubmed

Sodium channels and mammalian sensory mechanotransduction.

SCN9A SCN10A

2.12e-05393222449024
Pubmed

Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.

OBSCN OBSL1

2.12e-05393231098411
Pubmed

Sodium channel Na(v)1.7 is essential for lowering heat pain threshold after burn injury.

SCN9A SCN10A

2.12e-05393222875917
Pubmed

Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.

SCN2A SCN8A

2.12e-05393216033895
Pubmed

Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.

SCN2A SCN8A

2.12e-05393229991598
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN9A

2.12e-05393220038812
Pubmed

Synergistic regulation of serotonin and opioid signaling contributes to pain insensitivity in Nav1.7 knockout mice.

SCN9A SCN10A

2.12e-05393228074005
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

2.12e-05393227816501
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

2.12e-05393224704313
Pubmed

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

OBSCN OBSL1

2.12e-05393220133654
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

2.12e-05393219270815
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN2A SCN3A

2.12e-05393216052353
Pubmed

Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.

SCN9A SCN10A

2.12e-05393238999942
Pubmed

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain.

SCN9A SCN10A

2.12e-05393215314237
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

2.12e-05393225155934
Pubmed

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.

SCN1A SCN8A

2.12e-05393228117367
Pubmed

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain.

SCN8A SCN10A

2.12e-05393229497094
Pubmed

Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.

SCN9A SCN10A

2.12e-05393230554136
Pubmed

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

SCN3A SCN10A

2.12e-05393217052333
Pubmed

Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of NaV1.2 and NaV1.6.

SCN2A SCN8A

2.12e-05393238514708
Pubmed

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

SCN1A SCN8A

2.12e-05393226182346
Pubmed

De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.

SCN1A SCN8A

2.12e-05393231054517
InteractionSCN11A interactions

CACNA1B SCN1A SCN8A SCN9A SCN10A

4.60e-0915905int:SCN11A
InteractionCACNA1B interactions

CACNA1B SIGMAR1 SCN1A SCN9A OBSL1

6.18e-0737905int:CACNA1B
InteractionSCN5A interactions

CACNA1B SCN1A SCN8A SCN9A SCN10A

2.10e-0647905int:SCN5A
InteractionCACNA1D interactions

CACNA1B SCN1A SCN9A SCN10A

3.69e-0624904int:CACNA1D
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

4.75e-068903int:SCN4B
InteractionSCN1A interactions

CACNA1B SCN1A SCN9A SCN10A

8.11e-0629904int:SCN1A
InteractionNALCN interactions

CACNA1B SCN1A SCN9A

3.03e-0514903int:NALCN
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A SCN9A

1.35e-04127934chr2q24
Cytoband2q24

SCN3A SCN9A

2.21e-04119322q24
CytobandEnsembl 112 genes in cytogenetic band chr19p13

PODNL1 CPAMD8 KISS1R NRTN USHBP1 LINGO3 RTBDN PTGER1

2.22e-04797938chr19p13
Cytoband2q24.3

SCN1A SCN2A

4.78e-04169322q24.3
CytobandEnsembl 112 genes in cytogenetic band chr9q34

CACNA1B AJM1 SNAPC4 FUT7 PKN3

5.39e-04325935chr9q34
Cytoband19q13.3

GPR4 NOP53 CLPTM1

6.35e-048293319q13.3
Cytoband3p21.31

TCAIM NBEAL2 DALRD3

1.13e-031009333p21.31
Cytoband9q34.3

AJM1 SNAPC4 FUT7

1.33e-031069339q34.3
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.58e-1696371203
GeneFamilyTTT complex

TTI2 TTI1

3.58e-0536321320
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

RASL10A GPR4 TRABD2A CPAMD8 PTPRB USHBP1 PKN3

7.89e-08173937ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

RASL10A GPR4 TRABD2A CPAMD8 PTPRB USHBP1 PKN3

7.89e-0817393722200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 SGSM2 SCN1A SCN2A SCN8A SIDT1 EPHA10

1.29e-071869377278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1B DRD2 SCN2A SCN3A SCN8A RNF183

2.77e-06188936c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 GLDC SCN2A SCN3A PTGER1 PAPSS2

2.86e-061899363a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 GLDC SCN2A SCN3A PTGER1 PAPSS2

3.13e-061929360bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM2 SCN1A SCN2A SCN8A SIDT1 EPHA10

3.22e-06193936be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM2 SCN1A SCN2A SCN8A SIDT1 EPHA10

3.22e-061939360c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGSM2 SCN1A SCN2A SCN8A SIDT1 EPHA10

3.22e-061939368689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell(6)_Endothelial-B_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

RASL10A GPR4 CPAMD8 PTPRB USHBP1 PKN3

3.32e-061949360cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCellproximal-Endothelial-Capillary-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PODNL1 NPR1 TEPSIN PTPRB USHBP1 NOD2

3.63e-06197936ddb8ea895f0f34d4f20a0740b708fa0f3e378801
ToppCellproximal-Endothelial-Capillary|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PODNL1 NPR1 TEPSIN PTPRB USHBP1 NOD2

3.63e-0619793653baef54bd85c60ae24a3c163b3a3d937fb6ff0b
ToppCellproximal-3-Endothelial-Capillary|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PODNL1 NPR1 TEPSIN PTPRB USHBP1 NOD2

3.63e-06197936a1a61c03d67272693ec23e0d15f0a12bf618e2da
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RASL10A GPR4 CPAMD8 PTPRB PAPSS2 PKN3

3.63e-0619793656afed433887cb2766eb30f22aec195148db33ab
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RASL10A GPR4 CPAMD8 PTPRB PAPSS2 PKN3

3.73e-061989361b9200e30f1d9b91bb0c6411c4f95208aedbe161
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RASL10A GPR4 CPAMD8 PTPRB PAPSS2 PKN3

3.73e-061989367e2d6e21b2b3d5a4a9f786890ec6ba2688a506cc
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RASL10A CPAMD8 PTPRB USHBP1 PAPSS2 PKN3

3.73e-0619893655378e15360f867c9500b03293814965562ae55d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

CACNA1B SCN2A SCN9A OBSCN LGR6 CPNE7

3.96e-0620093661d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Artery-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPR4 CPAMD8 PTPRB USHBP1 PAPSS2 PKN3

3.96e-06200936622206c33640cb2694fe158e8dc55515bb7bd4f5
ToppCellParenchyma_COVID-19-Endothelial-TX-Artery|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TRABD2A CPAMD8 NPR1 PTPRB USHBP1 PKN3

3.96e-0620093634b279804475ea58fbb052b96f44128c082627a9
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Artery|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GPR4 CPAMD8 PTPRB USHBP1 PAPSS2 PKN3

3.96e-062009365b4a54cd81bc4d9f5e92798362239e1aa1b70bee
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRABD2A CPAMD8 NPR1 PTPRB USHBP1 PKN3

3.96e-062009368552cc7a439449b30b59760c3e8667217b9852b5
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Artery|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

GPR4 CPAMD8 PTPRB USHBP1 PAPSS2 PKN3

3.96e-06200936590d1c0f86f136c7e76ea107fbb8ac5ff1164386
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRABD2A CPAMD8 NPR1 PTPRB USHBP1 PKN3

3.96e-0620093645c08f1befe78553bbadcc2fcffb6138306638f3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SBK1 VPS9D1 MFHAS1 GLDC SCN2A

8.51e-06132935295980f70645ee2934145e9959c01f999044da3e
ToppCellremission-unassigned|World / disease stage, cell group and cell class

CAPN12 MFHAS1 SCN9A SRCAP CPNE7

1.85e-05155935d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|367C / Donor, Lineage, Cell class and subclass (all cells)

LINGO3 LGR6 RAB11FIP4 FUT7 CYP2W1

2.16e-05160935ab633295cb4de88fdbc076295e1352769f47cc00
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

TEPSIN SMPD1 MESP1 PHF8 CPNE7

2.57e-051669354ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

RASL10A GPR4 PTPRB USHBP1 PKN3

2.80e-05169935605cc2638271803cf1d972ab3fa8f13f89666376
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

RASL10A GPR4 PTPRB USHBP1 PKN3

2.80e-05169935337be3bf485b54afad86e256cb0c4c1d0c2a9a2a
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THEM6 RASL10A TRABD2A PTPRB PKN3

3.05e-05172935de9b11ab109d04937186c09772cec9105a935f95
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SBK1 OTUB2 ZNF672 TTI1 RAB11FIP4

3.14e-0517393523e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCelldroplet-Fat-Bat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAIM GLDC OBSL1 PHF8 CPNE7

3.31e-05175935b4f01e7782cdd107d0817ef601891fd3a382bc35
ToppCelldroplet-Fat-Bat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAIM GLDC OBSL1 PHF8 CPNE7

3.31e-05175935ef6f811d8e1839f405c3b41090ddf79be57a099f
ToppCelldroplet-Fat-Bat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAIM GLDC OBSL1 PHF8 CPNE7

3.31e-051759357f7598d46d10bff1cbea42f950bdde1aaa16e9a4
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1B SCN1A SCN2A SCN3A EPHA10

3.69e-05179935af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN3A RNF183 MESP1 RTBDN EPHA10

3.79e-051809356b1606238417490e0d9930870a7827419d1c3737
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

CACNA1B SCN2A SCN3A SCN8A RNF183

3.99e-0518293557bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B SCN3A SCN9A EPHA10 CPNE7

4.21e-051849353e5c68a99c10eb1ddc1048bea4aa9f6b8e2746ff
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1B SCN3A SCN9A EPHA10 CPNE7

4.21e-051849351e2f0cec50475a1cf2973a5082826bbc60fc9a68
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEM6 PTPRB SH2B3 USHBP1 SIDT1

4.32e-05185935602536a3308a848f106adcb0a83530997440c8f4
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 NPR1 PTPRB MYO1C USHBP1

4.32e-05185935a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1B SCN2A SCN3A SCN8A RNF183

4.43e-05186935b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 GLDC SCN2A SCN3A PAPSS2

4.54e-05187935e3095455d2f255854f339f6b05fa87852af0700f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NPR1 USHBP1 SCN9A PKN3

4.66e-0518893573f6ec915934154f435a376cb274b058ff7c5f35
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CACNA1B SCN2A SCN3A SCN9A EPHA10

4.66e-05188935b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 GLDC SCN2A SCN3A PAPSS2

4.78e-05189935532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NPR1 PTPRB USHBP1 SCN9A

4.90e-05190935a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR4 PTPRB USHBP1 PKN3 NOD2

4.90e-051909352655df8c0883dd811fa7617301f9c4b0a4dd55ec
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

USHBP1 SCN2A SCN3A SCN9A RTBDN

5.02e-0519193576311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

CPAMD8 PTPRB MFHAS1 SIDT1 PAPSS2

5.02e-05191935ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 NPR1 USHBP1 SCN9A PKN3

5.15e-05192935c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellIPF-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

TRABD2A CPAMD8 PTPRB SIDT1 PAPSS2

5.15e-05192935e911e286da26202853f9650ba3cdefe5a5c9b585
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 THEM6 NPR1 PTPRB PKN3

5.15e-05192935ac3d87aa301d30515c369bd7fc16f33b82173a85
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B SCN2A SCN3A SIDT1 EPHA10

5.28e-05193935461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B SCN2A SCN3A SIDT1 EPHA10

5.28e-051939350dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCND3 PITPNM2 CPAMD8 MFHAS1 GLDC

5.28e-05193935f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 GLDC SCN3A PTGER1 PAPSS2

5.28e-05193935e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CCND3 PITPNM2 CPAMD8 MFHAS1 GLDC

5.28e-0519393542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 SCN2A SCN3A PTGER1 PAPSS2

5.41e-05194935be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 SCN2A SCN3A PTGER1 PAPSS2

5.41e-051949354d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 PTPRB SEMA5B USHBP1 CPNE7

5.41e-051949359d7cbbcf995274019ca10be0562f114513ec197a
ToppCelldroplet-Bladder-Unstain-18m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 PTPRB SEMA5B USHBP1 CPNE7

5.54e-05195935fbfe4a8ae9775764108b45920eec92003b24fb2e
ToppCellproximal-Endothelial-Capillary_Aerocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PITPNM2 RASL10A GPR4 NPR1 USHBP1

5.54e-05195935f1cbf82484f489fe7e0b5de6a49ea28d69f04e1a
ToppCellproximal-Endothelial-Capillary_Aerocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PITPNM2 RASL10A GPR4 NPR1 USHBP1

5.54e-0519593513168c9632b58dd65ecb365df3832d95e7325919
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 PTPRB SEMA5B USHBP1 CPNE7

5.54e-051959352a6056172c41c46acfe0242be22269ef1d07921e
ToppCellproximal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PITPNM2 RASL10A GPR4 NPR1 USHBP1

5.54e-0519593536b2e754ed7ff138ac05fb51f4494e5339669828
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B SCN1A SCN2A SCN3A SCN8A

5.96e-05198935c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DRD2 SCN2A SCN3A SCN8A RNF183

5.96e-051989358f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B SCN1A SCN2A SCN3A SCN8A

5.96e-051989356d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASL10A CPAMD8 PTPRB USHBP1 PKN3

5.96e-051989358a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B SCN1A SCN2A SCN3A SCN8A

5.96e-051989354ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DRD2 SCN2A SCN3A SCN8A RNF183

5.96e-05198935e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor-1|TCGA-Testes / Sample_Type by Project: Shred V9

PNMA6F KISS1R TMEM88B CPNE7

5.99e-05101934d1112a5edda7da38f454a15a0b8b25180099510c
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RASL10A CPAMD8 PTPRB USHBP1 PKN3

6.10e-05199935bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR4 NPR1 PTPRB USHBP1 PAPSS2

6.10e-05199935c5c12c8288fe868322bae9d691b91fee953ceb3e
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPR4 CPAMD8 PTPRB USHBP1 PKN3

6.10e-05199935fff88d2bba262583bb726900ae01e44954b72eb9
ToppCelldistal-2-Endothelial-Artery|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RASL10A GPR4 TRABD2A CPAMD8 PTPRB

6.10e-05199935fa8aaf7a90699e41a7a4cee5614f8c9248110327
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Macrophage / Region, Cell class and subclass

DNHD1 MFHAS1 NBEAL2 SCN9A PDXP

6.10e-05199935fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCelldistal-Endothelial-Artery-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RASL10A GPR4 TRABD2A CPAMD8 PTPRB

6.10e-051999353788f3218356aaaa10684e48d63757037f8a3a3c
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPR4 CPAMD8 PTPRB USHBP1 PKN3

6.25e-05200935ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PITPNM2 GPR4 NPR1 PTPRB USHBP1

6.25e-052009355ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 CPAMD8 NPR1 USHBP1 SCN9A

6.25e-0520093566f7e8ee63c828f17468e79a4b816346b33e8980
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 NPR1 PTPRB USHBP1 SCN9A

6.25e-05200935a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 NPR1 PTPRB USHBP1 SCN9A

6.25e-052009351d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 NPR1 PTPRB USHBP1 SCN9A

6.25e-05200935d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PITPNM2 NPR1 PTPRB USHBP1 SCN9A

6.25e-0520093560d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

CACNA1B SCN2A SCN9A OBSCN CPNE7

6.25e-052009355c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYO3A NRTN NYX CPNE7

6.72e-05104934b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-A|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PITPNM2 RAB11FIP4 F7 EPHA10

8.96e-05112934d21cfcb04a27cc9fb74e0c2afa8a8cdfb886ae21
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF672 TPCN2 TCAIM GLDC

1.29e-04123934a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-6|TCGA-Lung / Sample_Type by Project: Shred V9

RASL10A USHBP1 STARD9 SCN1A

1.41e-04126934b49b15ba1458488f98d54e87100257a12ee34076
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

PTPRB USHBP1 PKN3 NOD2

2.06e-0413993434398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

PTPRB USHBP1 PKN3 NOD2

2.06e-04139934450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO3A DRD2 F7

2.07e-0455933948f26841f18d2d45f74c7c0c7b5be10737a4f43
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO3A DRD2 F7

2.07e-0455933616be3c334949ab0264293b9771d494381d74fb4
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO3A DRD2 F7

2.07e-0455933ed14bdb80cf2ff171b0dfc391ac0b150da344992
ToppCellLPS-antiTNF-Endothelial-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KISS1R SCN2A ALOXE3 SMPD1

2.36e-0414493475b16adfbe84f69376e6566d531ba7919d5c5192
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

GPR4 PTPRB USHBP1 PKN3

2.42e-0414593437580218f6a6f65a1d827cbcf59465f8827f9a55
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B SCN1A SCN9A SCN10A

2.42e-0414593496712c68ab759d7ade0d912581a1a7c25dc6def8
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN4A SCN8A SCN10A

5.77e-126925ctd:C475726
DrugZonisamide

SCN1A SCN2A SCN3A SCN4A SCN9A

5.75e-0917925DB00909
Drugisradipine

CACNA1B DRD2 TPCN2 SCN3A SCN4A SCN9A SCN10A PDXP

7.16e-09100928CID000003784
Drugdihydrochloride

DRD2 PTPRB SIGMAR1 SCN3A SCN4A SCN9A SCN10A SMPD1 PKN3

1.67e-08159929CID000070978
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A SCN10A

1.73e-088924ctd:C489827
Drugtetradotoxin

CACNA1B NPR1 DRD2 SIGMAR1 SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A PTGER1 PKN3 NOD2

1.77e-084289213CID000020382
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN4A SCN9A

6.38e-083923ctd:C561228
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A SCN10A

2.55e-074923ctd:C501880
DrugGBR 12909

DRD2 SIGMAR1 SCN3A SCN4A SCN9A SCN10A

3.60e-0769926CID000003455
Drugbenzocaine

SCN2A SCN3A SCN4A SCN9A SCN10A

3.80e-0737925CID000002337
Druglamotrigine

CACNA1B TPCN2 SCN2A SCN3A SCN4A SCN9A SCN10A

4.55e-07116927CID000003878
DrugCAS 298-57-7

CACNA1B DRD2 TPCN2 PDXP PTGER1 NOD2

5.05e-0773926CID000002761
Drug1, 3-diallylurea

SCN3A SCN4A SCN9A SCN10A SMPD1 VPS51

5.48e-0774926CID000074537
DrugTetrodotoxin

KISS1R SCN2A SCN3A SCN8A SCN9A

5.68e-0740925ctd:D013779
Drugverapamil

CACNA1B MYO3A DRD2 TPCN2 SCN3A SCN4A SCN9A SCN10A PDXP VPS51 BIRC6 PKN3

6.58e-074909212CID000002520
DrugScorpion Venoms

SCN2A SCN3A SCN4A SCN9A

7.31e-0718924ctd:D012604
Drugbupivacaine

SIGMAR1 SCN3A SCN4A SCN9A SCN10A PTGER1 PKN3

7.55e-07125927CID000002474
Drugbepridil

CACNA1B TPCN2 SCN3A SCN4A SCN9A SCN10A BIRC6

7.97e-07126927CID000002351
Drugdiprafenone

SCN3A SCN4A SCN9A SCN10A

9.24e-0719924CID000071249
Drugspiradoline

SIGMAR1 SCN3A SCN4A SCN9A SCN10A

1.16e-0646925CID000005620
DrugSodium

NPR1 SCN2A SCN3A SCN8A SCN9A SCN10A

1.16e-0684926ctd:D012964
Drugfenpropathrin

SCN2A SCN3A SCN10A

1.27e-066923ctd:C044267
Drugclenbuterol

MYO3A MYO1C SCN3A SCN4A CYP51A1 SCN9A SCN10A

1.78e-06142927CID000002783
Drugdecamethrin

CACNA1B DRD2 SCN1A SCN2A SCN3A SCN8A SCN10A

2.14e-06146927ctd:C017180
Drugpropafenone

SCN3A SCN4A CYP51A1 SCN9A SCN10A CYP2W1

2.88e-0698926CID000004932
Drugprocaine

CACNA1B TPCN2 SCN3A SCN4A SCN9A SCN10A PKN3

2.93e-06153927CID000004914
DrugAC1NT1AF

SCN3A SCN4A SCN9A SCN10A

2.96e-0625924CID005322157
Drugphenytoin

CACNA1B TPCN2 SIGMAR1 SCN2A SCN3A SCN4A SCN9A SCN10A

3.00e-06219928CID000001775
DrugPirmenolum

SCN3A SCN4A SCN9A SCN10A

3.49e-0626924CID000004853
DrugPbTx-1

SCN3A SCN4A SCN9A SCN10A

4.08e-0627924CID006437089
DrugAC1L1MOZ

SCN3A SCN4A SCN9A SCN10A

4.08e-0627924CID000031958
Drugnefopam

SCN3A SCN4A SCN9A SCN10A

4.08e-0627924CID000004450
DrugGTP[S]

CACNA1B GPR4 NPR1 DRD2 TPCN2 SIGMAR1 SCN3A SCN4A SCN9A SCN10A PTGER1 PKN3

4.59e-065919212CID000001764
Drugparaben

SCN3A SCN4A SCN9A SCN10A

4.75e-0628924CID000007175
Drugtocainide

SCN3A SCN4A SCN9A SCN10A

6.31e-0630924CID000038945
Drugsaxitoxin

SCN2A SCN3A SCN4A SCN9A SCN10A

6.58e-0665925CID000037165
Drugnifedipine

CACNA1B MYO3A NPR1 TPCN2 CYP51A1 SMPD1 BIRC6 PKN3 CYP2W1 NOD2

6.92e-064159210CID000004485
Drugmexiletine

CACNA1B SCN3A SCN4A SCN9A SCN10A

7.10e-0666925CID000004178
Drugdibucaine

CACNA1B SCN3A SCN4A SCN9A SCN10A

8.23e-0668925CID000003025
DrugNSC93767

SCN3A SCN4A SCN9A SCN10A

8.23e-0632924CID000005658
DrugNSC7524

CACNA1B DRD2 SCN2A SCN3A SCN4A SCN9A SCN10A

9.18e-06182927CID000005657
Drughydrochlorothiazide

SCN3A SCN4A SCN9A SCN10A PDXP SMPD1

9.31e-06120926CID000003639
Drug5-hydroxypropafenone

SCN3A SCN4A SCN9A SCN10A

1.06e-0534924CID000107927
Drugsipatrigine

CACNA1B SCN2A SCN4A SCN9A

1.49e-0537924CID000060803
Drugisoproterenol

CACNA1B MYO3A NPR1 DRD2 MYO1C SCN3A SCN4A SCN9A SCN10A SMPD1 PTGER1 PKN3

1.59e-056699212CID000003779
DrugBupivacaine

SCN10A PTGER1

1.62e-052922DB00297
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

1.62e-052922ctd:C502265
Drugaprindine

SCN3A SCN4A SCN9A SCN10A

1.66e-0538924CID000002218
Drugbupropion

DRD2 SCN3A SCN4A SCN9A SCN10A

1.94e-0581925CID000000444
DrugS-ropivacaine

SCN3A SCN4A SCN9A SCN10A

2.04e-0540924CID000071273
Drugpilsicainide

SCN3A SCN4A SCN9A SCN10A

3.58e-0546924CID000004820
Drugindoxacarb

SCN3A SCN4A SCN9A SCN10A

4.60e-0549924CID000107720
Druggabapentin

CACNA1B TPCN2 SCN3A SCN4A SCN9A SCN10A

6.44e-05169926CID000003446
DrugAC1NSN3X

SCN3A SCN4A SCN9A SCN10A

6.76e-0554924CID005366189
Drugpyraclofos

CACNA1B SCN2A SCN4A SCN9A SMPD1

7.09e-05106925CID000093460
Drugriluzole

CACNA1B NRTN SCN3A SCN4A SCN9A SCN10A

7.57e-05174926CID000005070
Drugfenfluramine

SCN3A SCN4A SCN9A SCN10A SMPD1 BIRC6

8.58e-05178926CID000003337
Drugcarbamazepine

DRD2 SCN2A SCN3A SCN4A SCN9A SCN10A

8.85e-05179926CID000002554
Drugtriamterene

SCN3A SCN4A SCN9A SCN10A

8.96e-0558924CID000005546
DrugLidocaine

SCN9A SCN10A

9.64e-054922DB00281
DrugPropofol

SCN2A SCN4A

9.64e-054922DB00818
DrugFospropofol

SCN2A SCN4A

9.64e-054922DB06716
Drugalpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol

DRD2 SIGMAR1

9.64e-054922ctd:C050408
DrugAY9944

SCN2A CYP51A1 SMPD1

1.07e-0423923CID000009704
Drugzonisamide

SCN3A SCN4A SCN9A SCN10A

1.16e-0462924CID000005734
Drugethanol

CACNA1B DRD2 SIGMAR1 SCN3A SCN4A SCN9A SCN10A PTGER1 BIRC6 F7 CYP2W1 NOD2

1.37e-048379212CID000000702
DrugZalcitabine [7481-89-2]; Up 200; 19uM; MCF7; HT_HG-U133A

VPS9D1 SIGMAR1 SCN10A ALOXE3 SRCAP FUT7

1.38e-041949267352_UP
DrugAC1L1AY5

NPR1 SMPD1 PTGER1

1.38e-0425923CID000001202
DrugMulticide

SCN2A SCN4A SCN9A

1.38e-0425923CID000024365
DrugAC1L1CQC

SCN3A SCN4A SCN9A SCN10A

1.40e-0465924CID000002012
DrugTribenoside [10310-32-4]; Down 200; 8.4uM; HL60; HT_HG-U133A

THEM6 DGLUCY CLPTM1 SRCAP FUT7 DALRD3

1.41e-041959262946_DN
DrugDiethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; HL60; HT_HG-U133A

THEM6 PODNL1 NPR1 SCN4A PAPSS2 CYP2W1

1.41e-041959262394_UP
DrugCarcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A

DRD2 SCN4A ALOXE3 NYX PHF8 FUT7

1.45e-041969264225_UP
Drugdisopyramide

SCN3A SCN4A SCN9A SCN10A

1.49e-0466924CID000003114
Drugresiniferatoxin

SCN3A SCN4A SCN9A SCN10A

1.49e-0466924CID000104826
DrugScopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

FBXO38 GPR4 DRD2 PTPRB SMPD1 CPNE7

1.50e-041979264803_UP
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; HL60; HT_HG-U133A

SCN10A ALOXE3 SMPD1 SRCAP CYP2W1 CPNE7

1.50e-041979262554_DN
Drug6-Furfurylaminopurine [525-79-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A

OBSL1 SMPD1 PTGER1 CYP2W1 CPNE7 NOD2

1.50e-041979266813_UP
DrugEthoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A

FBXO38 DRD2 SCN8A ALOXE3 SNAPC4 CPNE7

1.54e-041989263764_DN
DrugBenzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A

THEM6 GPR4 PTPRB PTGER1 PAPSS2 CYP2W1

1.54e-041989262989_DN
Druggallopamil

CACNA1B TPCN2 BIRC6 NOD2

1.58e-0467924CID000001234
DrugNifurtimox [23256-30-6]; Up 200; 14uM; PC3; HT_HG-U133A

FBXO38 NPR1 PTPRB NRTN OBSL1 SRCAP

1.58e-041999266608_UP
DrugDiflunisal [22494-42-4]; Up 200; 16uM; PC3; HT_HG-U133A

NPR1 DRD2 NRTN SCN3A ALOXE3 NOD2

1.58e-041999264210_UP
DrugRemoxipride

DRD2 SIGMAR1

1.60e-045922DB00409
DrugNSC-9618

NPR1 SH2B3

1.60e-045922CID000407806
Drugcinuperone

DRD2 SIGMAR1

1.60e-045922CID000133831
DrugT2755

SCN3A SCN4A SCN9A SCN10A

1.97e-0471924CID000005514
Drugflecainide

SCN3A SCN4A SCN9A SCN10A

1.97e-0471924CID000003355
Drugsynthetic pyrethrins

CACNA1B SCN4A CYP51A1 SCN9A

1.97e-0471924CID000002982
Drugcyfluthrin

SCN2A SCN3A SCN10A

2.16e-0429923ctd:C052570
Drugimide

SCN3A SCN4A SCN9A SCN10A

2.31e-0474924CID000443040
Drugcarpipramine

DRD2 SIGMAR1

2.40e-046922CID000002580
Drug[11c]sa4503

DRD2 SIGMAR1

2.40e-046922CID009820591
Drugdiphenhydramine

SCN3A SCN4A SCN9A SCN10A

2.44e-0475924CID000003100
Drugpentobarbital

SIGMAR1 SCN3A SCN4A SCN9A SCN10A PKN3

2.99e-04224926CID000004737
Drugsalbutamol

NPR1 SCN3A SCN4A SCN9A SCN10A

3.18e-04146925CID000002083
Drugumespirone

DRD2 SIGMAR1

3.35e-047922CID000065902
Drugfluorocyclobutane

SCN2A SCN4A

3.35e-047922CID011051569
DrugGR218,231

DRD2 SIGMAR1

3.35e-047922CID005312124
Drugbenzothiazolone

DRD2 SIGMAR1

3.35e-047922CID000013625
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.96e-1610887DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.96e-1610887DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

1.29e-1512887DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA1B SCN1A SCN2A SCN3A SCN4A SCN8A SCN9A SCN10A

3.22e-08163888DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

5.18e-0722884DOID:2030 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

2.13e-069883C3502809
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

7.17e-0613883C0751122
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

8.79e-062882C4551549
DiseaseB Virus Infection

SCN8A SCN9A

2.63e-053882C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

2.63e-053882cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

2.63e-053882C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

2.63e-053882C0019372
DiseasePrimary Erythermalgia

SCN9A SCN10A

2.63e-053882C0014805
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN9A SCN10A

2.63e-053882C1833661
DiseaseSpinal muscular atrophy, Jerash type

FBXO38 SIGMAR1

8.74e-055882C1854023
DiseaseMovement Disorders

CACNA1B DRD2 SCN1A

8.85e-0529883C0026650
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

1.31e-046882C0220669
DiseaseNeurodevelopmental Disorders

SCN1A SCN2A SCN8A SRCAP

1.76e-0493884C1535926
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.83e-047882C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.83e-047882C0751057
DiseaseCongenital Pain Insensitivity

SCN9A SCN10A

1.83e-047882C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN9A SCN10A

1.83e-047882C0020075
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

2.43e-048882C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

2.43e-048882C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

2.43e-048882C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

2.43e-048882C0751120
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

2.43e-048882C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

2.43e-048882C0393703
Diseaseleft ventricular systolic function measurement

MYO1C SH2B3 OBSCN

3.11e-0444883EFO_0008206
DiseaseFebrile Convulsions

SCN1A SCN2A

3.12e-049882C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

3.12e-049882C0014550
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A

3.24e-04109884C0014544
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

3.90e-0410882C0917800
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

4.75e-0411882C0393702
DiseaseMMR-related febrile seizures

SCN1A SCN2A

9.00e-0415882EFO_0006519
DiseaseNeuralgia, Supraorbital

SCN9A SCN10A

1.03e-0316882C0038870
DiseaseNeuralgia

SCN9A SCN10A

1.03e-0316882C0027796
DiseaseNeuralgia, Atypical

SCN9A SCN10A

1.03e-0316882C0234247
DiseaseNeuralgia, Stump

SCN9A SCN10A

1.03e-0316882C0234249
DiseaseNeuralgia, Iliohypogastric Nerve

SCN9A SCN10A

1.03e-0316882C0423712
DiseaseNeuralgia, Perineal

SCN9A SCN10A

1.03e-0316882C0423711
DiseaseParoxysmal Nerve Pain

SCN9A SCN10A

1.03e-0316882C0751373
DiseaseNerve Pain

SCN9A SCN10A

1.03e-0316882C0751372
DiseaseNeuralgia, Ilioinguinal

SCN9A SCN10A

1.03e-0316882C0751371
DiseaseNeuralgia, Vidian

SCN9A SCN10A

1.03e-0316882C0042656
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

1.03e-0316882C0393706
Diseaseaggressive behaviour measurement, ADHD symptom measurement

DRD2 MFHAS1 BIRC6

1.12e-0368883EFO_0007826, EFO_0007860
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

1.30e-0318882HP_0002373
Diseasediabetes mellitus (biomarker_via_orthology)

CYP51A1 F7

1.45e-0319882DOID:9351 (biomarker_via_orthology)
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A

1.91e-0382883C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A

1.91e-0382883C0751111
DiseaseAura

SCN1A SCN2A SCN8A

1.91e-0382883C0236018
DiseaseEtat Marbre

DRD2 SCN1A

2.14e-0323882C0266487
Diseasetraumatic brain injury (biomarker_via_orthology)

DRD2 METTL14

2.33e-0324882DOID:0081292 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QDSFSLAHPLLRRLR

USHBP1

256

Q8N6Y0
LAFILHRLSLPRDRQ

CCND3

161

P30281
ARHVPLYRALLELLR

BIRC6

4386

Q9NR09
ARLHRIVPRLRDVFG

SMPD1

71

P17405
LRLRGVFLRHEFPRV

AJM1

906

C9J069
RAILRTLLEARRPHV

CYP2W1

241

Q8TAV3
FRHPRRLLLALRGEA

DNHD1

4586

Q96M86
ALLDAVRSFRIRHRP

NPR1

951

P16066
FDLRTLRAVRVLRPL

CACNA1B

186

Q00975
PAALLRSVRRLREVF

RAB11FIP4

11

Q86YS3
HRLPRTLDARIARLA

NRTN

41

Q99748
HDRTLARLSVRPRQL

OBSL1

1526

O75147
LSILRDHPENRIYRR

OTUB2

16

Q96DC9
RRRLLERGYKHPVLL

PAPSS2

426

O95340
RLSIRRDRPLSVHLN

PTPRB

1656

P23467
PRLFRVASKRHRDLL

PCDHA8

61

Q9Y5H6
AALRAARLRHQELFR

NOP53

356

Q9NZM5
DPRHLRRLRDKLLSV

MFHAS1

631

Q9Y4C4
NPHFRDDLRRLRPRA

LGR6

831

Q9HBX8
LPLLLDHRTRELRAR

ALOXE3

126

Q9BYJ1
RRRLHLFGRDSTIRP

METTL14

341

Q9HCE5
HLRLRQVLSRARPSE

PNMA6F

381

A0A0J9YX94
RPLLHAARVSVARAR

PTGER1

141

P34995
RLSLHGDIRLLFSRR

FAM214B

496

Q7L5A3
RARLYRQLAPHLRVD

FUT7

186

Q11130
FPLRALHRRTPRLAL

KISS1R

146

Q969F8
LHRRTPRLALAVSLS

KISS1R

151

Q969F8
PRGSFRDLVRLRELH

LINGO3

286

P0C6S8
PLRDRLSFLHRLPIL

TEPSIN

6

Q96N21
RERAATLLHLRPGAR

EPHA10

406

Q5JZY3
ASRLEPLLERRFHAL

PITPNM2

766

Q9BZ72
YLAVAHPLRFARLRR

GPR4

116

P46093
ARRLHRLFRTKSPAE

OBSCN

5011

Q5VST9
HRAFRRLRALRSLDL

PODNL1

401

Q6PEZ8
VRKARHRRTLFASPL

POM121

96

Q96HA1
ARLLRLYRRHEPRFP

FJX1

386

Q86VR8
RPLTRARSRLSHVLL

FBXO38

866

Q6PIJ6
PRSHALLPRLLRADR

CAPN12

466

Q6ZSI9
RPLRLTRFDVAVRAH

CPAMD8

966

Q8IZJ3
LRLSCRHLLDRDPLT

CPNE7

26

Q9UBL6
LPLPSFRRRDRAHRE

CYP51A1

251

Q16850
YLSDRISLHRRLPER

GALNT12

106

Q8IXK2
RSRDFLAPHRALQAR

DALRD3

36

Q5D0E6
KRSSRAFRAHLRAPL

DRD2

226

P14416
HLRSRLPSAIRSLIL

DGLUCY

6

Q7Z3D6
RFLKHELTSELRRRP

SBK1

311

Q52WX2
AHPLRSRVTRELRAA

PKN3

246

Q6P5Z2
LHARTFAALSRLRRL

NYX

126

Q9GZU5
EHLQRALRSRFRLRL

RTBDN

91

Q9BSG5
LRFGPRRALAALVRR

RASL10A

136

Q92737
RLLKSRILFHPRSLR

TCAIM

351

Q8N3R3
LAHLSLVTPARRRLL

RNF183

41

Q96D59
LRALRPLRALSRFEG

SCN4A

1131

P35499
RHRRSLRLLEPFEVR

THEM6

106

Q8WUY1
HYRARVEVRLPRDLL

RIMBP3

1051

Q9UFD9
HRRRRANAFLEELRP

F7

56

P08709
FRRPLAQLREVHLRR

NBEAL2

1966

Q6ZNJ1
LRPRRSIAFRLRLAS

GMCL2

446

Q8NEA9
LLHQLRRRAAGFLRS

SGSM2

51

O43147
TLRALRPLRALSRFE

SCN9A

1291

Q15858
LAFSRLIVELRRLHP

SIGMAR1

56

Q99720
LLRHDFVRRDRPLRV

TAOK3

271

Q9H2K8
LRALRPLRALSRFEG

SCN3A

1306

Q9NY46
NFPVHLSRIRRLRAE

STARD9

1546

Q9P2P6
RTLARALHELRRFLP

MESP1

96

Q9BRJ9
DTFLPRHRLSRRVLL

SRCAP

961

Q6ZRS2
NTEPRKRFHLLSRLR

SRP68

146

Q9UHB9
SRRARPELALRFARL

PDXP

61

Q96GD0
RTLRALRPLRALSRF

SCN1A

1316

P35498
ALRHPIQVSRRLLSR

ATAD3B

296

Q5T9A4
RLDREHRVAGIFPRL

CLPTM1

441

O96005
LRLRLRAEAVRPHSA

CNNM3

101

Q8NE01
SLLVRALDRFHRRLR

VPS51

366

Q9UID3
ALDRFHRRLRAPGAL

VPS51

371

Q9UID3
RRTRYPDIHLRERLA

MIXL1

106

Q9H2W2
ARDLQSHRPAIVRRL

NOD2

131

Q9HC29
EPEHRLLLRRTYARN

TTI2

351

Q6NXR4
TLRALRPLRALSRFE

SCN10A

1251

Q9Y5Y9
FLLIVLRRDILHRRA

SIDT1

511

Q9NXL6
RRFPHLPALLLHRRR

ZNF672

106

Q499Z4
RTLRALRPLRALSRF

SCN2A

1306

Q99250
RTLRALRPLRALSRF

SCN8A

1296

Q9UQD0
SLRHIFRRRSAGELP

SH2B3

141

Q9UQQ2
LDRHISTELRLPRRG

TRABD2A

456

Q86V40
EPLRSLRILHSARAL

SEMA5B

526

Q9P283
LASAVRARLARRLRP

TMEM88B

121

A6NKF7
TLTFRALRRALCRLP

TLCD1

16

Q96CP7
ILDIFRGLRENRRHP

PHF8

411

Q9UPP1
HRRLLNRRLLLAVTP

SNAPC4

736

Q5SXM2
PLLLALYRSVHRARE

VPS9D1

456

Q9Y2B5
LFLELIRARRPLVLH

TOE1

176

Q96GM8
HEPLRIRRLLRPFFL

TPCN2

181

Q8NHX9
HRLTRDAPLAVLRAF

TTI1

916

O43156
RLLERLLPRHDDFAR

GLDC

51

P23378
TIRRLIRGFVLRHAP

MYO1C

786

O00159
ARIRRLGFSHRILFA

MYO3A

981

Q8NEV4