Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone binding	TSPY3 TSPY9 TSPY2 CHD2 TSPY1 JAK2 NCAPD2 CDYL PRMT7 SMARCA5 TSPY4 RRP8 TSPY8 TSPY10	8.81e-07	265	210	14	GO:0042393
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3C RIMBP3 RIMBP3B	1.13e-05	5	210	3	GO:0030156
GeneOntologyBiologicalProcess	gonadal mesoderm development	TSPY3 TSPY9 TSPY2 TSPY1 TSPY4 TSPY8 TSPY10	3.39e-13	9	208	7	GO:0007506
GeneOntologyBiologicalProcess	mesoderm development	TSPY3 TSPY9 TSPY2 TSPY1 JAK2 WNT3A WNT3 TSPY4 TSPY8 TSPY10	4.53e-06	157	208	10	GO:0007498
GeneOntologyBiologicalProcess	nucleosome organization	TSPY3 TSPY9 TSPY2 CHD2 TSPY1 SMARCA5 TSPY4 TSPY8 TSPY10	1.42e-05	142	208	9	GO:0034728
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	LDLRAP1 DISC1 TOGARAM1 EPS8L1 PPP1R15A MFF ANLN KHDC3L G3BP2 WNT3A MAD1L1 NCAPD2 TRPV2 PDXP GPSM2 EEF2K PML CARMIL2 KALRN WNT3 CCT4 GRID2 ICE1 ABCG1 APPL2 ANO6 EIF4G2 MARK2 IL2RB SLX4 PINK1	1.85e-05	1366	208	31	GO:0051130
GeneOntologyBiologicalProcess	nucleosome assembly	TSPY3 TSPY9 TSPY2 TSPY1 SMARCA5 TSPY4 TSPY8 TSPY10	3.37e-05	122	208	8	GO:0006334
GeneOntologyBiologicalProcess	sexual reproduction	RAD18 BRIP1 CENPC TSPY3 SPO11 TSPY9 TSPY2 TSPY1 RMI1 ANTXR2 TUBGCP3 NCAPD2 DIAPH2 RIMBP3C CDYL PRMT7 CRTAP ATP8B3 WNT3 TSPY4 CCT4 TSPY8 PKMYT1 RIMBP3 EHHADH TSPY10 RIMBP3B NEURL4 SLX4	5.70e-05	1312	208	29	GO:0019953
GeneOntologyBiologicalProcess	axon extension	DISC1 FSTL4 NRP2 WNT3A TRPV2 WNT3 SPG11 EIF4G2	6.93e-05	135	208	8	GO:0048675
GeneOntologyBiologicalProcess	positive regulation of collateral sprouting in absence of injury	WNT3A WNT3	1.01e-04	2	208	2	GO:0048697
GeneOntologyBiologicalProcess	mesenchyme development	TSPY3 TSPY9 TSPY2 TSPY1 NRP2 WNT3A SEMA3B LDLRAD4 TSPY4 TSPY8 DCHS1 TSPY10 SPRED1	1.10e-04	372	208	13	GO:0060485
GeneOntologyCellularComponent	microtubule	DISC1 EML6 FAM161B TOGARAM1 MTUS1 TUBGCP3 DNAH9 DYNC2H1 CCT4 HID1 KIFC2 SHROOM1 HOOK3 EHHADH PCNT KIF1C	9.20e-05	533	208	16	GO:0005874
Domain	PH_dom-like	LDLRAP1 TBC1D2 EPS8L1 PHLDA2 NIBAN3 JAK2 PTPN14 ANLN FGD1 IRS4 KALRN TRIOBP PTPN21 APPL2 SPRED1 LRBA	1.79e-05	426	203	16	IPR011993
Domain	NAP_family	TSPY2 TSPY4 TSPY8 TSPY10	2.89e-05	17	203	4	IPR002164
Domain	NAP	TSPY2 TSPY4 TSPY8 TSPY10	2.89e-05	17	203	4	PF00956
Domain	Wnt3	WNT3A WNT3	1.18e-04	2	203	2	IPR009141
Domain	Tyr_Pase_non-rcpt_typ-14/21	PTPN14 PTPN21	1.18e-04	2	203	2	IPR014392
Domain	PRKG1_interact	PPP1R12B PPP1R12C	3.50e-04	3	203	2	IPR031775
Domain	PRKG1_interact	PPP1R12B PPP1R12C	3.50e-04	3	203	2	PF15898
Domain	MYPT1/MYPT2_chordates	PPP1R12B PPP1R12C	3.50e-04	3	203	2	IPR017401
Domain	ARM-type_fold	PDS5B CAND2 TOGARAM1 NCAPD2 DIAPH2 ATXN10 ARMC7 ECPAS CWC22 ARMCX3 EIF4G2 LRBA	3.50e-04	339	203	12	IPR016024
Domain	-	LDLRAP1 TBC1D2 PHLDA2 NIBAN3 PTPN14 ANLN FGD1 IRS4 KALRN TRIOBP PTPN21 APPL2 SPRED1	3.64e-04	391	203	13	2.30.29.30
Domain	GPS	PKD1L2 CELSR1 CELSR3 ADGRD2	4.87e-04	34	203	4	SM00303
Domain	GPS	PKD1L2 CELSR1 CELSR3 ADGRD2	5.45e-04	35	203	4	PF01825
Domain	GPS	PKD1L2 CELSR1 CELSR3 ADGRD2	6.08e-04	36	203	4	PS50221
Domain	ANF_lig-bd_rcpt	GRID2 GPRC6A GABBR2 GUCY2F	6.76e-04	37	203	4	IPR001828
Domain	ANF_receptor	GRID2 GPRC6A GABBR2 GUCY2F	6.76e-04	37	203	4	PF01094
Domain	GPS	PKD1L2 CELSR1 CELSR3 ADGRD2	6.76e-04	37	203	4	IPR000203
Domain	Matrilin_ccoil	MATN1 MATN4	6.95e-04	4	203	2	SM01279
Domain	-	MATN1 MATN4	6.95e-04	4	203	2	1.20.5.30
Domain	Matrilin_ccoil	MATN1 MATN4	6.95e-04	4	203	2	PF10393
Domain	TRPV1-4_channel	TRPV2 TRPV1	6.95e-04	4	203	2	IPR008347
Domain	Matrilin_coiled-coil_trimer	MATN1 MATN4	6.95e-04	4	203	2	IPR019466
Domain	-	PDS5B CAND2 TOGARAM1 NCAPD2 ATXN10 ARMC7 ECPAS ARMCX3 LRBA	7.42e-04	222	203	9	1.25.10.10
Domain	Peripla_BP_I	GRID2 GPRC6A GABBR2 GUCY2F	8.27e-04	39	203	4	IPR028082
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDS5B RAD18 BRIP1 RBM10 SF3A1 TBC1D2 ANLN MAD1L1 CCDC86 MED13 MRTFA SMARCA5 NACC1 PARG BAG3 ECPAS ZNF106 EIF4G2 SCRIB EIF3G MARK2 PCM1	2.95e-09	774	213	22	15302935
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RAD18 PHLDA2 ANLN MAD1L1 NCAPD2 NHS EEF2K MRTFA SMARCA5 KALRN BAG3 RRP8 HOOK3 SCRIB MARK2 PCM1 KIF1C	1.68e-08	503	213	17	16964243
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PDS5B ASXL1 RAD18 CENPC SF3A1 PPP1R12B CEP76 RMI1 ANLN TUBGCP3 MAD1L1 CRTAP CWC15 TRIOBP CWC22 PKMYT1 ZNF106 SCRIB EIF3G MARK2 NEURL4 SLX4 PCM1 PPP1R12C KIF1C	5.22e-08	1155	213	25	20360068
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LDLRAP1 ARMCX4 GPSM2 ATXN10 DGCR8 LNX1 UAP1L1 MED13 CRTAP KALRN POLR1C TRIOBP ZNF251 APPL2 CELSR3 CIAO3 LGI3 EIF4G2 SPRED1 SCRIB LRBA TRIM37 SLX4 PCM1 PINK1 PCNT	1.04e-07	1285	213	26	35914814
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PPP1R12B CHD2 RRAS MFF GGCX ANLN SUPT7L NCAPD2 CDYL DGCR8 CCDC86 MED13 POLR1C TRIOBP CCT4 RRP8 ICE1 NOL9 SRBD1 KIAA1671 CCNT1 CELSR1 APPL2 EIF4G2 EIF3G MARK2 IMP3 PPP1R12C	1.62e-07	1497	213	28	31527615
Pubmed	PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport.	PTPN21 HOOK3 KIF1C	2.27e-07	3	213	3	31217419
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	RAD18 CENPC MAD1L1 NCAPD2 CDYL SMARCA5 RRP8 PKMYT1 PCM1 PCNT	7.67e-07	210	213	10	16565220
Pubmed	Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis.	HOOK3 PCM1 PCNT	9.02e-07	4	213	3	20152126
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3C RIMBP3 RIMBP3B	9.02e-07	4	213	3	19091768
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RBM10 SF3A1 PRMT7 PML SMARCA5 IRS4 NACC1 CWC15 PARG BAG3 CCT4 ICE1 KIAA1671 CCNT1 EIF4G2 SCRIB EIF3G LRBA PCM1 PCNT	1.44e-06	934	213	20	33916271
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PRAG1 PTPN14 MTUS1 ANLN MAD1L1 NHS PML IRS4 CARMIL2 BAG3 PTPN21 MAP3K6 KIAA1671 ZNF106 SCRIB MARK2 PCM1 PPP1R12C KIF1C	1.72e-06	861	213	19	36931259
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PDS5B RAD18 BRIP1 CENPC RBM10 SF3A1 ANLN DGCR8 CCDC86 PML SMARCA5 IRS4 CWC15 RRP8 ICE1 CWC22 CCNT1 EIF4G2 SLX4 PCM1	1.98e-06	954	213	20	36373674
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CENPC PPP1R12B PTPN14 MTUS1 NHS ATXN10 CCDC86 IRS4 BAG3 TRIOBP CCT4 HID1 PTPN21 PTPRU TARS2 KIAA1671 CNNM1 SCRIB NEURL4 PPP1R12C PCNT	2.24e-06	1049	213	21	27880917
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3C RIMBP3 RIMBP3B	2.24e-06	5	213	3	17855024
Pubmed	Analysis of phosphatase and tensin homolog tumor suppressor interacting proteins by in vitro and in silico proteomics.	CENPC PTPN14 G3BP2 IRS4 PINK1	2.66e-06	36	213	5	15717329
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	LDLRAP1 RAD18 RBM10 SF3A1 ANLN G3BP2 TUBGCP3 MAD1L1 NCAPD2 SMARCA5 CWC15 CCT4 SCRIB MARK2 PCNT	3.52e-06	582	213	15	20467437
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CAND2 CENPC SF3A1 PTPN14 TUBGCP3 EEF2K ATXN10 PML DYNC2H1 CWC15 BAG3 POLR1C TRIOBP SPG11 RRP8 NOL9 TARS2 PKMYT1 ANO6 EIF4G2 SCRIB MARK2 NEURL4 PCM1 PCNT	5.22e-06	1487	213	25	33957083
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PTPN14 MTUS1 PROSER3 MINDY4 POLR1C CCT4 ECPAS RIMBP3 KIAA1671 HOOK3 EIF4G2 RASEF EIF3G NEURL4 TRIM37 PCM1 PCNT KIF1C	6.03e-06	853	213	18	28718761
Pubmed	A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development.	DYNC2H1 SCRIB PCNT	7.79e-06	7	213	3	15314648
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	CENPC RBM10 SF3A1 ABT1 ANLN DGCR8 CCDC86 PML SMARCA5 NACC1 BAG3 POLR1C CCT4 RRP8 NOL9 SRBD1 CWC22 ZNF106 IMP3	1.24e-05	989	213	19	36424410
Pubmed	The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors.	DISC1 PCM1 PCNT	1.24e-05	8	213	3	22031837
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PDS5B CHD2 CEP76 NCAPD2 DIAPH2 SMARCA5 CWC15 SPG11 RRP8 ECPAS ZNF106 MARK2 LRBA	1.37e-05	497	213	13	36774506
Pubmed	Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.	NRP2 CELSR1 DCHS1	1.85e-05	9	213	3	28705793
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	PPP1R12B GGCX PROSER3 G3BP2 TUBGCP3 CCDC86 BAG3 TARS2 ECPAS ARMCX3 ANO6 EIF3G MARK2 NEURL4 PCM1 PCNT	1.88e-05	754	213	16	33060197
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	RBM10 ABT1 G3BP2 NKTR PML SMARCA5 IRS4 GPATCH2 RRP8 SCRIB IMP3 SLX4	1.96e-05	440	213	12	34244565
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	DUS3L IRS4 TARS2 CCNT1 ZNF106 SCRIB MARK2 LRBA IMP3	2.02e-05	242	213	9	34011540
Pubmed	ATRX proximal protein associations boast roles beyond histone deposition.	CENPC PML NOL9 ZNF106 ATF3 IMP3	2.13e-05	91	213	6	34780483
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	RAD18 BRIP1 RBM10 RMI1 ANLN DGCR8 MED13 PML ICE1 ZNF106 ATF3 SLX4	2.60e-05	453	213	12	29656893
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SF3A1 ABT1 PTPN14 FAM83F ANLN G3BP2 PML SMARCA5 CWC15 POLR1C OAS3 CCT4 RRP8 NOL9 SRBD1 CWC22 KIAA1671 SCRIB EIF3G MARK2 IMP3	3.39e-05	1257	213	21	36526897
Pubmed	JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML.	JAK2 PML	3.73e-05	2	213	2	33075130
Pubmed	Cannabidiol enhances microglial phagocytosis via transient receptor potential (TRP) channel activation.	TRPV2 TRPV1	3.73e-05	2	213	2	24641282
Pubmed	JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation.	JAK2 PML	3.73e-05	2	213	2	25143485
Pubmed	High disease activity in ankylosing spondylitis is associated with increased serum sclerostin level and decreased wingless protein-3a signaling but is not linked with greater structural damage.	WNT3A SOST	3.73e-05	2	213	2	23509994
Pubmed	A combination of cytomorphology, cytogenetic analysis, fluorescence in situ hybridization and reverse transcriptase polymerase chain reaction for establishing clonality in cases of persisting hypereosinophilia.	JAK2 PCM1	3.73e-05	2	213	2	16769584
Pubmed	Kendrin/pericentrin-B, a centrosome protein with homology to pericentrin that complexes with PCM-1.	PCM1 PCNT	3.73e-05	2	213	2	11171385
Pubmed	DISC1-kendrin interaction is involved in centrosomal microtubule network formation.	DISC1 PCNT	3.73e-05	2	213	2	18955030
Pubmed	Mutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes.	GGCX ABCC6	3.73e-05	2	213	2	18800149
Pubmed	Up-regulation of TRPV1 in mononuclear cells of end-stage kidney disease patients increases susceptibility to N-arachidonoyl-dopamine (NADA)-induced cell death.	TRPV2 TRPV1	3.73e-05	2	213	2	19619644
Pubmed	The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2.	JAK2 PCM1	3.73e-05	2	213	2	15805263
Pubmed	DISC1 localizes to the centrosome by binding to kendrin.	DISC1 PCNT	3.73e-05	2	213	2	15094396
Pubmed	Regulation of WNT3 and WNT3A mRNAs in human cancer cell lines NT2, MCF-7, and MKN45.	WNT3A WNT3	3.73e-05	2	213	2	11788904
Pubmed	An Exceptional Gene: Evolution of the TSPY Gene Family in Humans and Other Great Apes.	TSPY9 TSPY1	3.73e-05	2	213	2	24710137
Pubmed	ALOX12B and PNPLA1 Have Distinct Roles in Epidermal Lipid Lamellar Organization.	PNPLA1 ALOX12B	3.73e-05	2	213	2	36116510
Pubmed	PCM1-JAK2 fusion in myeloproliferative disorders and acute erythroid leukemia with t(8;9) translocation.	JAK2 PCM1	3.73e-05	2	213	2	16034466
Pubmed	Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein".	TSPY9 TSPY1	3.73e-05	2	213	2	9678360
Pubmed	Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1.	ALOX12B ALOXE3	3.73e-05	2	213	2	11773004
Pubmed	Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex.	TRPV2 TRPV1	3.73e-05	2	213	2	16115206
Pubmed	Expression of transient receptor potential vanilloid 1 (TRPV1) and 2 (TRPV2) in human peripheral blood.	TRPV2 TRPV1	3.73e-05	2	213	2	16777226
Pubmed	Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.	WNT3A WNT3	3.73e-05	2	213	2	2001840
Pubmed	TSPY-related sequences represent a microheterogeneous gene family organized as constitutive elements in DYZ5 tandem repeat units on the human Y chromosome.	TSPY9 TSPY1	3.73e-05	2	213	2	8244388
Pubmed	Altered erythropoiesis via JAK2 and ASXL1 mutations in myeloproliferative neoplasms.	ASXL1 JAK2	3.73e-05	2	213	2	38340948
Pubmed	The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain.	DISC1 PCM1	3.73e-05	2	213	2	20360304
Pubmed	Distribution of TRPV1 and TRPV2 in the human stellate ganglion and spinal cord.	TRPV2 TRPV1	3.73e-05	2	213	2	25641129
Pubmed	Should myeloid and lymphoid neoplasms with PCM1-JAK2 and other rearrangements of JAK2 be recognized as specific entities?	JAK2 PCM1	3.73e-05	2	213	2	24913195
Pubmed	ASXL1 and JAK2V617F gene mutation screening in Iranian patients with chronic myeloid leukemia.	ASXL1 JAK2	3.73e-05	2	213	2	27640403
Pubmed	Blockade of epithelial sodium channels improves sperm motility in asthenospermia patients.	SCNN1A SCNN1D	3.73e-05	2	213	2	18298571
Pubmed	ASXL1 mutation confers poor prognosis in primary myelofibrosis patients with low JAK2V617F allele burden but not in those with high allele burden.	ASXL1 JAK2	3.73e-05	2	213	2	33046688
Pubmed	Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3.	ALOX12B ALOXE3	3.73e-05	2	213	2	15629692
Pubmed	ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis.	ATF3 PINK1	3.73e-05	2	213	2	29363258
Pubmed	TRP vanilloid 2 knock-out mice are susceptible to perinatal lethality but display normal thermal and mechanical nociception.	TRPV2 TRPV1	3.73e-05	2	213	2	21832173
Pubmed	Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins.	WNT3A SOST	3.73e-05	2	213	2	15545262
Pubmed	Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families.	MMP21 PRMT7	3.73e-05	2	213	2	26437029
Pubmed	Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis.	CELSR1 SCRIB	3.73e-05	2	213	2	22095531
Pubmed	t(8;9)(p22;p24)/PCM1-JAK2 activates SOCS2 and SOCS3 via STAT5.	JAK2 PCM1	3.73e-05	2	213	2	23372669
Pubmed	The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier.	ALOX12B ALOXE3	3.73e-05	2	213	2	24021977
Pubmed	DISC-1 Leu607Phe alleles differentially affect centrosomal PCM1 localization and neurotransmitter release.	DISC1 PCM1	3.73e-05	2	213	2	19455170
Pubmed	Microtubule affinity-regulating kinase 2 (MARK2) turns on phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) at Thr-313, a mutation site in Parkinson disease: effects on mitochondrial transport.	MARK2 PINK1	3.73e-05	2	213	2	22238344
Pubmed	ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFA axis-mediated neoplastic fibrocyte generation in myeloproliferative neoplasms.	ASXL1 JAK2	3.73e-05	2	213	2	36005555
Pubmed	Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance.	TRPV2 TRPV1	3.73e-05	2	213	2	24322617
Pubmed	Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B.	ALOX12B ALOXE3	3.73e-05	2	213	2	19131948
Pubmed	ASXL1 alteration cooperates with JAK2V617F to accelerate myelofibrosis.	ASXL1 JAK2	3.73e-05	2	213	2	30651633
Pubmed	Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis.	TSPY9 TSPY1	3.73e-05	2	213	2	29974883
Pubmed	A t(8;9) translocation with PCM1-JAK2 fusion in a patient with T-cell lymphoma.	JAK2 PCM1	3.73e-05	2	213	2	16424865
Pubmed	Nociceptors lacking TRPV1 and TRPV2 have normal heat responses.	TRPV2 TRPV1	3.73e-05	2	213	2	15254097
Pubmed	Evolutional change of karyotype with t(8;9)(p22;p24) and HLA-DR immunophenotype in relapsed acute myeloid leukemia.	JAK2 PCM1	3.73e-05	2	213	2	18594780
Pubmed	Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum.	PTPN21 KIF1C	3.73e-05	2	213	2	9685376
Pubmed	TSPY, the candidate gonadoblastoma gene on the human Y chromosome, has a widely expressed homologue on the X - implications for Y chromosome evolution.	TSPY9 TSPY1	3.73e-05	2	213	2	15241014
Pubmed	12R-lipoxygenase deficiency disrupts epidermal barrier function.	ALOX12B ALOXE3	3.73e-05	2	213	2	17403930
Pubmed	Targeting TRPV1 and TRPV2 for potential therapeutic interventions in cardiovascular disease.	TRPV2 TRPV1	3.73e-05	2	213	2	23453732
Pubmed	CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress.	JAK2 SIGLEC1	3.73e-05	2	213	2	23502962
Pubmed	Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients.	ALOX12B ALOXE3	3.73e-05	2	213	2	33435499
Pubmed	The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene.	JAK2 PCM1	3.73e-05	2	213	2	16091753
Pubmed	A capsaicin-receptor homologue with a high threshold for noxious heat.	TRPV2 TRPV1	3.73e-05	2	213	2	10201375
Pubmed	Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope.	ALOX12B ALOXE3	3.73e-05	2	213	2	21558561
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	ABT1 ATXN10 DGCR8 CCDC86 SMARCA5 IRS4 POLR1C CCT4 RRP8 NOL9 MARK2 IMP3	4.83e-05	483	213	12	36912080
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	ASXL1 SF3A1 G3BP2 SUPT7L TUBGCP3 CRTAP DYNC2H1 BAG3 POLR1C RRP8 ICE1 SRBD1 SHQ1 EIF4G2 SCRIB EIF3G MARK2 NEURL4	5.25e-05	1005	213	18	19615732
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PDS5B RAD18 CENPC ABT1 CHD2 MAD1L1 NCAPD2 ATXN10 MED13 PML SMARCA5 NACC1 POLR1C CCT4 ECPAS CCNT1 EIF4G2 EIF3G	5.88e-05	1014	213	18	32416067
Pubmed	Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea.	GPSM2 WNT3 CELSR1 PCNT	6.17e-05	35	213	4	32907846
Pubmed	Autosomal Recessive Congenital Ichthyosis	PNPLA1 ALOX12B ALOXE3	6.19e-05	13	213	3	20301593
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	CD300A FSTL4 CHAT SEMA3B KALRN PTPRU SIGLEC1	6.69e-05	162	213	7	25826454
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBM10 SF3A1 ABT1 PHLDA2 MFF G3BP2 TUBGCP3 ATXN10 CCDC86 SMARCA5 POLR1C CCT4 RRP8 NOL9 CCNT1 IMP3	7.47e-05	847	213	16	35850772
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3C RIMBP3 RIMBP3B	7.84e-05	14	213	3	17662146
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	TOGARAM1 EPS8L1 PKD1L2 GGCX CCDC86 DNAH9 BAG3 ICE1 SHROOM1 CELSR3	8.53e-05	361	213	10	26167880
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B CENPC MYO9B CHD2 DUS3L PTPN14 ANLN TUBGCP3 NCAPD2 CCDC86 ALOX12B SMARCA5 BAG3 POLR1C OAS3 CCT4 NOL9 SRBD1 CCNT1 EIF4G2 SCRIB	9.63e-05	1353	213	21	29467282
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARMCX4 EHD3 G3BP2 MAD1L1 DIAPH2 KALRN NACC1 TRIOBP CCT4 NOL9 GABBR2 HOOK3 DCHS1 SCRIB NEURL4 PCM1 PCNT	1.01e-04	963	213	17	28671696
Pubmed	AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair.	PRSS16 AJM1 SCNN1D KATNIP ARMCX3 SPRED1	1.05e-04	121	213	6	31900314
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	SF3A1 TUBGCP3 POLR1C CCT4 CWC22 SHQ1 EHHADH PCM1 KIF1C	1.06e-04	300	213	9	28561026
Pubmed	The DNA sequence of human chromosome 22.	SF3A1 PDXP ATXN10 MRTFA BPIFC TRIOBP RIMBP3 CELSR1 IL2RB	1.06e-04	300	213	9	10591208
Pubmed	Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure.	ASXL1 JAK2	1.12e-04	3	213	2	34210413
Pubmed	The role of lipoxygenases in epidermis.	ALOX12B ALOXE3	1.12e-04	3	213	2	23954555
Interaction	TSPY8 interactions	TSPY3 TSPY2 TSPY8	1.07e-06	3	207	3	int:TSPY8
Cytoband	Yp11.2	TSPY3 TSPY9 TSPY2 TSPY1 TSPY4 TSPY8 TSPY10	3.05e-07	94	213	7	Yp11.2
Cytoband	Ensembl 112 genes in cytogenetic band chrYp11	TSPY3 TSPY9 TSPY2 TSPY1 TSPY4 TSPY8 TSPY10	7.03e-06	150	213	7	chrYp11
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	1.20e-04	3	115	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR3	1.20e-04	3	115	2	1189
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R12B PPP1R15A PPP1R26 GPATCH2 PKMYT1 SPRED1 PPP1R12C	1.58e-04	181	115	7	694
GeneFamily	Sodium channels epithelial	SCNN1A SCNN1D	2.39e-04	4	115	2	185
GeneFamily	Blood group antigens\|CD molecules\|ATP binding cassette subfamily G	ABCG8 ABCG1	3.96e-04	5	115	2	811
GeneFamily	Arachidonate lipoxygenases	ALOX12B ALOXE3	5.92e-04	6	115	2	407
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARMCX4 ARMC7 ARMCX3	2.57e-03	43	115	3	409
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	JAK2 PTPN14 PTPN21	3.95e-03	50	115	3	1293
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	ASXL1 CENPC MYO9B SF3A1 PPP1R12B NCAPD2 MED13 CNNM1 ZNF106 PCM1	2.06e-06	180	210	10	M8239
Coexpression	GSE27786_NKCELL_VS_NKTCELL_DN	ARMCX4 ANTXR2 ETNK1 ARMC7 NOL9 ZNF251 CCDC82 EIF3G TRIM37 PCNT	5.04e-06	199	210	10	M4852
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRP2 EHD3 JAK2 MTUS1 MINDY4 KALRN LAMA4 HOOK3	2.68e-06	181	213	8	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD1 NRP2 EHD3 CHST15 MTUS1 CRTAP LAMA4 TRIM37	2.68e-06	181	213	8	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	droplet-Liver-Npc-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EHD3 CHST15 MINDY4 LDLRAD4 CRTAP LAMA4 DCHS1 TRIM37	3.28e-06	186	213	8	75258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R12B NRP2 JAK2 ANTXR2 KALRN LAMA4 GRID2 GPC6	4.83e-06	196	213	8	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R12B NRP2 JAK2 ANTXR2 KALRN LAMA4 GRID2 GPC6	4.83e-06	196	213	8	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CENPC CHD2 JAK2 NKTR SMARCA5 OAS3 SIGLEC1 PCM1	5.60e-06	200	213	8	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KHDC3L KIFC2 KIAA1671 SIGLEC1 LRBA NEURL4 KIF1C	1.32e-05	162	213	7	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MATN4 EPS8L1 PPP1R26 SEMA3B SCNN1A CELSR1 LGI3	2.02e-05	173	213	7	45808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MATN4 EPS8L1 PPP1R26 SEMA3B SCNN1A CELSR1 LGI3	2.02e-05	173	213	7	7fa9dbcb258c3ab974490063951620e2def03db1
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPC PTPN14 SUPT7L DGCR8 MINDY4 PTPN21 MAP3K6	2.18e-05	175	213	7	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD18 CAND2 TOGARAM1 MATN4 ANLN MAP3K6 SLC2A13	2.52e-05	179	213	7	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS16 PHLDA2 FFAR4 FAM83F SCNN1A HID1 RASEF	3.00e-05	184	213	7	886d2d9bf2fe31207f17e3edc309ef44029924e1
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS16 PHLDA2 FFAR4 FAM83F SCNN1A HID1 RASEF	3.00e-05	184	213	7	936b39377eebea3961d702532779f6cd27953be7
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DISC1 NRP2 ANTXR2 LDLRAD4 APPL2 SPRED1 SIGLEC1	3.11e-05	185	213	7	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LDLRAP1 NRP2 PPP1R26 MTUS1 KALRN LAMA4 HID1	3.22e-05	186	213	7	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	COVID-19_Mild-Neu_4\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	RAD18 CENPC NIBAN3 EEF2K PRMT7 ICE1 SHQ1	3.33e-05	187	213	7	714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-ELP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NIBAN3 C1QTNF4 ATXN10 TSGA10IP BANK1 LDLRAD4 ENAM	3.44e-05	188	213	7	0a47de24812c619f6756c9351a413b109128d54f
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	THSD1 NRP2 PTPN14 CHST15 KALRN LAMA4 KIAA1671	3.44e-05	188	213	7	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THSD1 NRP2 PTPN14 CHST15 KALRN LAMA4 KIAA1671	3.44e-05	188	213	7	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THSD1 NRP2 PTPN14 CHST15 KALRN LAMA4 KIAA1671	3.44e-05	188	213	7	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PDS5B RAD18 BRIP1 ANLN MAD1L1 NCAPD2 DGCR8	3.68e-05	190	213	7	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	PPP1R15A NRP2 CHST15 KALRN BAG3 ABCG1 ATF3	3.81e-05	191	213	7	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ASXL1 PPP1R15A PTPN14 FBXO34 MRTFA BAG3 ATF3	4.07e-05	193	213	7	dbf0fe496254320c894568c31e5f9ce63707d1b5
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	G3BP2 GAL3ST3 SYN2 CARMIL2 GABBR2 CNNM1 TRIM37	4.07e-05	193	213	7	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LDLRAP1 PHLDA2 PDXP ALOX12B BPIFC RRP8 SYTL1	4.20e-05	194	213	7	bd94d30584128628b34ed8c3857ce103586cfe2e
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte-new-cluster\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LDLRAP1 PHLDA2 PDXP ALOX12B BPIFC RRP8 SYTL1	4.20e-05	194	213	7	b847c5b4e8914b1c306bfff3d7119c32063784a8
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRIP1 FFAR4 ANLN NCAPD2 PKMYT1 ABCG1 EHHADH	4.20e-05	194	213	7	effd38e51062b225ecabc7e1c50154e65495d559
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NRP2 PTPN14 CHST15 MTUS1 TRIOBP LAMA4 NTAN1	5.10e-05	200	213	7	76e90231aa94afc12e618da8ae314c51644acab4
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NRP2 PTPN14 CHST15 MTUS1 TRIOBP LAMA4 NTAN1	5.10e-05	200	213	7	e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Down 200; 8uM; MCF7; HT_HG-U133A	PRR4 EPS8L1 PTPN14 SEMA3B DIAPH2 PML PTPRU EHHADH ATF3 CDH6 PCM1	1.74e-06	196	205	11	3248_DN
Disease	Congenital ichthyosis	PNPLA1 ALOX12B ALOXE3	2.77e-06	5	194	3	C0020758
Disease	ICHTHYOSIS, CONGENITAL, AUTOSOMAL RECESSIVE 2	ALOX12B ALOXE3	4.30e-05	2	194	2	242100
Disease	Autosomal recessive congenital ichthyosis 2	ALOX12B ALOXE3	4.30e-05	2	194	2	cv:C3888093
Disease	ICHTHYOSIFORM ERYTHRODERMA, CONGENITAL, NONBULLOUS, 1	ALOX12B ALOXE3	4.30e-05	2	194	2	C1855792
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	PNPLA1 ALOX12B ALOXE3	4.44e-05	11	194	3	C0079154
Disease	Congenital ichthyosis of skin	PNPLA1 ALOX12B ALOXE3	4.44e-05	11	194	3	cv:C0020758
Disease	Prostatic Neoplasms	TBC1D2 MATN4 RRAS JAK2 ANTXR2 MAD1L1 ALOX12B PML IL17RC APPL2 EHHADH ALOXE3 ATF3 GREB1	6.28e-05	616	194	14	C0033578
Disease	Malignant neoplasm of prostate	TBC1D2 MATN4 RRAS JAK2 ANTXR2 MAD1L1 ALOX12B PML IL17RC APPL2 EHHADH ALOXE3 ATF3 GREB1	6.28e-05	616	194	14	C0376358
Disease	Familial hypercholesterolemia - homozygous	LDLRAP1 ABCG8	1.28e-04	3	194	2	C0342881
Disease	Self-Healing Collodion Baby	ALOX12B ALOXE3	1.28e-04	3	194	2	C1855789
Disease	attention deficit hyperactivity disorder, conduct disorder	MATN1 FSTL4 PKD1L2 CWC15	1.38e-04	40	194	4	EFO_0003888, EFO_0004216
Disease	revision of total hip arthroplasty, aseptic loosening	TBC1D2 ICE1 GABBR2 CELSR1	1.67e-04	42	194	4	EFO_0010725, EFO_0020973
Disease	Ichthyosis Congenita I	ALOX12B ALOXE3	2.56e-04	4	194	2	C4551630
Disease	Harlequin Fetus	ALOX12B ALOXE3	2.56e-04	4	194	2	C0239849
Disease	Ichthyosis Congenita II	ALOX12B ALOXE3	2.56e-04	4	194	2	C3536797
Disease	myeloproliferative neoplasm (implicated_via_orthology)	ASXL1 JAK2	2.56e-04	4	194	2	DOID:2226 (implicated_via_orthology)
Disease	Collodion Fetus	ALOX12B ALOXE3	2.56e-04	4	194	2	C3543867
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	FFAR4 RMI1 ABCG8 SPG11 ZNF106 LRBA	4.88e-04	150	194	6	EFO_0004611, EFO_0020947
Disease	adverse effect, response to xenobiotic stimulus	CENPC MAD1L1 SCNN1A LDLRAD4	6.22e-04	59	194	4	EFO_0009658, GO_0009410
Disease	smoking status measurement, triglyceride measurement	DGCR8 TMEM175	6.34e-04	6	194	2	EFO_0004530, EFO_0006527
Disease	hereditary lymphedema (is_implicated_in)	THSD1 CELSR1	8.84e-04	7	194	2	DOID:0050580 (is_implicated_in)
Disease	Myeloid Leukemia, Chronic	ASXL1 JAK2 ETNK1	9.01e-04	29	194	3	C0023473
Disease	myelofibrosis (is_implicated_in)	ASXL1 JAK2	1.17e-03	8	194	2	DOID:4971 (is_implicated_in)
Disease	NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO	CELSR1 SCRIB	1.17e-03	8	194	2	C3891448
Disease	platelet measurement	LDLRAP1 MYO9B EML6 EHD3 SYN2 BANK1 FBXO34 KALRN	1.20e-03	315	194	8	EFO_0005036
Disease	Situs ambiguous	MMP21 DNAH9	1.50e-03	9	194	2	C1167664
Disease	Congenital neurologic anomalies	FGD1 SPRED1	1.87e-03	10	194	2	C0497552
Disease	Cranioschisis	FGD1 SPRED1	1.87e-03	10	194	2	C0265541
Disease	cancer antigen 125 measurement	GAL3ST3 CIAO3	1.87e-03	10	194	2	EFO_0010603
Disease	small cell lung carcinoma	FSTL4 ABT1 DYNC2H1 IL17RC	1.94e-03	80	194	4	EFO_0000702
Disease	Schizophrenia	PRSS16 MYO9B DISC1 CHAT MAD1L1 SYN2 DGCR8 CCDC86 PML PTPN21 MARK2 PCM1 PINK1 PCNT	2.22e-03	883	194	14	C0036341
Disease	Ankylosing spondylitis	ANTXR2 ANO6	2.27e-03	11	194	2	C0038013
Disease	Situs Inversus	MMP21 DNAH9	2.27e-03	11	194	2	C0037221
Disease	spleen volume	MYO9B SYN2 KIF1C	2.85e-03	43	194	3	EFO_0600047
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	FFAR4 ABCG8 SPG11 ZNF106 NTAN1 LRBA	3.60e-03	222	194	6	EFO_0008317, EFO_0020943
Disease	Neuroblastoma	PTPN14 SEMA3B PINK1	3.67e-03	47	194	3	C0027819
Disease	Fanconi anemia	BRIP1 SLX4	3.72e-03	14	194	2	cv:C0015625
Disease	Testicular Germ Cell Tumor	MAD1L1 ALOX12B	3.72e-03	14	194	2	C1336708
Disease	Situs ambiguus	MMP21 DNAH9	4.27e-03	15	194	2	C0266642
Disease	hypertension	MYO9B EML6 FSTL4 GDF10 BANK1 OAS3 ANO6	4.35e-03	307	194	7	EFO_0000537
Disease	2-hydroxyglutarate measurement	GAL3ST3 PCNT	4.86e-03	16	194	2	EFO_0021506
Disease	substance-related disorder	ABT1 BANK1 C4orf54	4.88e-03	52	194	3	MONDO_0002494
Disease	Influenza	OAS3 ATF3 SIGLEC1	4.88e-03	52	194	3	C0021400
Disease	Moyamoya Disease	ABCC6 PCNT	5.48e-03	17	194	2	C0026654
Disease	ischemia (implicated_via_orthology)	SCNN1A SCNN1D	5.48e-03	17	194	2	DOID:326 (implicated_via_orthology)
Disease	Parkinson disease	BRIP1 MED13 WNT3 BAG3 TMEM175 CCDC82 SLC2A13	5.52e-03	321	194	7	MONDO_0005180
Disease	Major Depressive Disorder	DISC1 EHD3 KALRN GABBR2 PINK1 PCNT	5.57e-03	243	194	6	C1269683
Disease	gallstones	ABCG8 LIAS HID1 LRBA	5.70e-03	108	194	4	EFO_0004210
Disease	Bone marrow hypocellularity	BRIP1 SLX4	6.14e-03	18	194	2	C1855710
Disease	Schizophrenia	DISC1 SYN2	6.14e-03	18	194	2	cv:C0036341
Disease	level of Phosphatidylcholine (15:0_18:2) in blood serum	RAD18 NTAN1	6.14e-03	18	194	2	OBA_2045065
Disease	Hypercholesterolemia, Familial	LDLRAP1 ABCG8	6.14e-03	18	194	2	C0020445

Protein segments in the cluster

Peptide	Gene	Start	Entry
QDRARIESPAFSTLR	BANK1	656	Q8NDB2
PNRRADDNATIRVTN	EIF3G	231	O75821
SRTRRALVEFESNPE	CCDC86	26	Q9H6F5
SNNRRSADQIRPIFF	CARNMT1	261	Q8N4J0
TEAQRFSSLPRRAAV	ABCG1	61	P45844
ALFKEQRNRETAPRT	ATXN10	31	Q9UBB4
DVAQAQRSRPELTAR	CARMIL2	676	Q6F5E8
QREPGSLSRNNSFRR	FBXO34	296	Q9NWN3
VINNPARDDRSTSFQ	BTBD17	326	A6NE02
TDNDLRATERPSARA	AJM1	536	C9J069
LRAQEQPSCRRAFDL	ANTXR2	31	P58335
FDEQRRPGARRAASQ	C1QTNF4	106	Q9BXJ3
PRTFSQAQRDKRVED	ABCG8	176	Q9H221
PAQDSRARRSSEVLQ	ATP8B3	881	O60423
REQLENSPSRRFGVD	CCNT1	16	O60563
RLLDTPRQAARFVNV	CEP76	331	Q8TAP6
RSPETIFRQREISNE	LINC01600	111	Q96MT4
RASDRDSPINANLRY	CELSR1	376	Q9NYQ6
TTQDAPEEVRNRDFR	CWC15	46	Q9P013
ERAEQALRRFSQGPT	DUS3L	226	Q96G46
ESRARPFQALPREQS	DGCR8	21	Q8WYQ5
GAITTAAERNNRERF	DIAPH2	296	O60879
AAERNNRERFSPIVE	DIAPH2	301	O60879
DLAQAARNSSRPERD	DISC1	276	Q9NRI5
ARRAVQKRASPNSDD	ARMCX3	101	Q9UH62
LRANSQVEALPDARD	ARMCX4	436	Q5H9R4
VASRIQAEPDNLARA	ASXL1	486	Q8IXJ9
NSFQPISSLRDDERR	RBM10	671	P98175
HRVSRRAQQRAESPE	PDS5B	1346	Q9NTI5
RVRPADAEAVFQRLD	RASEF	41	Q8IZ41
QDTEISPRQNRRTRA	RAD18	466	Q9NS91
SPRQNRRTRAAESAE	RAD18	471	Q9NS91
RQRARDLSEQASAPL	RIMBP3B	466	A6NNM3
RQRARDLSEQASAPL	RIMBP3C	466	A6NJZ7
NQRPSFRDLALRVDQ	JAK2	1111	O60674
LQRSQAPAARAFLDA	NIBAN3	231	Q86XR2
DEAFSRLAQSRTNPQ	LDLRAP1	256	Q5SW96
IVDRDAFFNPATRSR	ANO6	196	Q4KMQ2
RSREAPRAQDFQRAE	MAB21L4	26	Q08AI8
ARQVSRAAAARRPNT	NOL9	66	Q5SY16
LLVEATDRPANASRR	DCHS1	1511	Q96JQ0
AQSPEESRAQNRRLL	PIP5KL1	311	Q5T9C9
SRRLDDQRASFSNLP	GPSM2	556	P81274
SRNELQVPRSFVDRV	H2AP	21	O75409
RPQDSVQDVSARARA	MATN1	156	P21941
QVQSVFPLRAFSRRE	MATN4	81	O95460
SLNPTSVARQRLRED	MAD1L1	546	Q9Y6D9
FREQANLEDRSPRRT	MAGEA11	66	P43364
EVRRRTFQARPLSAD	KIAA1671	496	Q9BY89
QTANAREDRPLFFLT	GREB1	1931	Q4ZG55
RSDSAPRNKISRFQA	MFF	176	Q9GZY8
LRRNSDNRNPSADRA	MTUS1	736	Q9ULD2
ANNTSEDRPQELRRS	KATNIP	171	O60303
EAPRRSIAAFQSRLA	ALOXE3	666	Q9BYJ1
QIEPANREFCARRNT	ANLN	1041	Q9NQW6
PSERNNYSRVANDRD	CWC22	791	Q9HCG8
AAQNLRFEDVPALRA	C1orf109	51	Q9NX04
NNSADPRVRRAAQAT	GDF10	281	P55107
AIRFAQRVSDQPLES	EHHADH	181	Q08426
LLRSRQAAETFPANI	ECPAS	341	Q5VYK3
ARERFSGPQLRQELA	MAP3K6	246	O95382
PTRQALEQISDFRNT	GRID2	911	O43424
DAPLRSLEQANRTRF	FFAR4	11	Q5NUL3
VPDNRRQAESLSLTR	PCM1	361	Q15154
QREASKRPSARVAAN	PINK1	491	Q9BXM7
AEAVRRFQRANALPA	MMP21	86	Q8N119
SDARSFPSRQRRVLD	PARG	26	Q86W56
LRDIFVQAQNRDSSP	FAM234B	341	A2RU67
NVILQEDFRRRPTAA	KALRN	2916	O60229
PDDRNFLRLQSDSQR	NRP2	681	O60462
ERSQPSLRARQASLE	PNPLA1	291	Q8N8W4
RVRPFNARETSQDAK	KIF1C	11	O43896
RRDSRSTVFRIPEFN	LRBA	1296	P50851
SRQVRQRSPDIFQEA	LNX1	461	Q8TBB1
SPASFEQERQRAQRQ	FAM161B	191	Q96MY7
SKVRDPRANFDQSLR	LIAS	246	O43766
RATNAQFDSPEILRR	TUBGCP3	606	Q96CW5
DFCSPRQVAEARSRQ	ARMC7	166	Q9H6L4
RPRRVNSSAFQEADI	PCDH10	891	Q9P2E7
RAIIEDLEPRFNNSS	HOOK3	566	Q86VS8
IPARSTRRDDNSAAN	EIF4G2	51	P78344
ARRSAEARQSPAAAE	PCNT	2891	O95613
TVSAKARPEDQRRQA	PKD1L2	986	Q7Z442
RIDPQSNSSQLREEF	PTPRU	1166	Q92729
ARLPENAERNRFQDV	PTPN21	916	Q16825
ALILVDDRFRNNPSR	BRIP1	841	Q9BX63
PAFLSDNTIEVRINR	GPRC6A	246	Q5T6X5
AFRRVPNASLEAFLR	GAL3ST3	171	Q96A11
PDTFLNALRQETARA	DYNC2H1	4176	Q8NCM8
FAQRPTEQELRARKA	ABT1	211	Q9ULW3
DNRFVQPRLESLVSR	CCDC82	381	Q8N4S0
QSTNFDKSRLRNRPV	ICE1	1501	Q9Y2F5
RSARSAPENFNTRFR	GPC6	351	Q9Y625
RFRLALPESNRSNIE	BPIFC	406	Q8NFQ6
DQPFDKRLRFSVRQT	CDYL	321	Q9Y232
RPRFGEINDQDRTDR	PRMT7	376	Q9NVM4
RFCRPSRARDINTEQ	CENPC	16	Q03188
RSNRSRQEPSRFNIK	CHD2	111	O14647
QSQPSREVLADFQRR	CRTAP	131	O75718
SSNPFTRAQEEERRR	COX11	76	Q9Y6N1
QNDSDNRRIIRYPDS	G3BP2	316	Q9UN86
RQDSPASAARQLLVD	FSTL4	661	Q6MZW2
ARLAIERINRDPSFD	GUCY2F	76	P51841
EFRALNARLPLNTDA	IL2RB	521	P14784
RAQNGRTPEDERNLF	ATF3	156	P18847
LPATEFLDQNRGSRR	APPL2	456	Q8NEU8
EAPRRSIEAFRQRLN	ALOX12B	656	O75342
QPREQARESLVSTFR	FBXO40	686	Q9UH90
AFRVQAFSRSSRPAQ	GLMP	191	Q8WWB7
QRSVSANPKQRRFSD	MARK2	396	Q7KZI7
TLRTNPDAATQNRRF	GABBR2	746	O75899
PERDQFRVRASAALL	IMP3	66	Q9NV31
AVTQRFREDARDPVT	KHDC3L	201	Q587J8
RRTPTARDNTDVRDF	CDH6	701	P55285
FDLSPRERDAVNQNT	EEF2K	326	O00418
SQNPFRDDVSTLRRN	ENAM	941	Q9NRM1
SAIQDIRISPDNRFL	EML6	1771	Q6ZMW3
FRTVLELQPRDSQAR	DNAH9	4196	Q9NYC9
PRSSSDNRNFLRERA	ETNK1	6	Q9HBU6
DNRNFLRERAGLSSA	ETNK1	11	Q9HBU6
RPEARKVTSANRARF	CELSR3	301	Q9NYQ7
RATQEELQRDRSPAA	EPS8L1	171	Q8TE68
SDFAVDNVGNRTLRR	GPATCH2	146	Q9NW75
RFRTEAAAAAPQRSQ	BAG3	121	O95817
QDPDLNVRRATLAFF	CAND2	1021	O75155
AAAFENLARERPRSL	C4orf54	1356	D6RIA3
RRARSVASSLRDNNP	SCNN1A	201	P37088
SPVAAASFQSRQEAR	SCNN1D	106	P51172
DPDGARRLREAQTIN	KIFC2	646	Q96AC6
TAERRRPLDEFNNGV	NEURL4	336	Q96JN8
RAEQVSRALQPALDS	IL17RC	751	Q8NAC3
RFARRITQAQEELSP	PPP1R15A	591	O75807
AAARRQPAARAAQAF	SCRIB	66	C0HLS1
RSRQPFFTQRELVDE	LAMA4	431	Q16363
RPASNVSASIQRIRE	LAMA4	806	Q16363
TPAAALDRFVARRLQ	OAS3	6	Q9Y6K5
ERRRPQSRSQSFFAA	IRS4	1081	O14654
RAARRQFQQDETPAF	SLC2A13	66	Q96QE2
LPDDSQASRQRTRVV	SYTL1	451	Q8IYJ3
QELTAAARPFRRLEA	TARS2	186	Q9BW92
RRRLSDSSFIANLPN	SYN2	6	Q92777
QRPRRGSISEEEQFS	TSGA10IP	236	Q3SY00
FVLENFSTLRQRADP	TRIM37	281	O94972
ERATQRQERFAERPA	PPP1R12C	716	Q9BZL4
DRREQRAAAPLSIAA	NHS	246	Q6T4R5
RLNRRPRNQESSSDE	NKTR	1286	P30414
NARVDESQRISFPRL	ABCC6	1151	O95255
RQRARDLSEQASAPL	RIMBP3	466	Q9UFD9
LQPLTFNRNADRSIE	RMI1	336	Q9H9A7
TPALDNVFFESLQRR	PML	101	P29590
PILFFLNDARADQSR	HID1	401	Q8IV36
ARLLEEARNRSSFPA	FGD1	401	P98174
STAALPENAERSRIR	PTPN14	926	Q15678
FTPAAERRQKRLAAE	SHQ1	176	Q6PI26
RQACAPQELERFSRF	SHROOM1	691	Q2M3G4
DRDKPAQIRFSNISA	CCT4	26	P50991
ASQDAALAFRVRRPA	PPP1R26	786	Q5T8A7
INRFRQAQPTSREER	PROSER3	106	Q2NL68
ANPRLDTFSREIFRN	POLR1C	276	O15160
QTNRSSFDLLPREFR	SUPT7L	16	O94864
APDSQVRFSNIRTND	MED13	501	Q9UHV7
DLDVVRRPRAASDSN	METTL22	121	Q9BUU2
RASFQDRGPEEQLRA	NTAN1	191	Q96AB6
RPRARSAKANQAELE	SOST	196	Q9BQB4
ARNGPEFEARIRQNE	SF3A1	61	Q15459
QDLFRDIQSLPRNAA	EHD3	276	Q9NZN3
RDFLSSPERQALRAA	FAM83F	56	Q8NEG4
SPAAFHEQRRSLERA	MRTFA	6	Q969V6
NLRSAVSIARRVQDP	SRBD1	651	Q8N5C6
AQRDNLRASSPIRAT	TRIOBP	796	Q9H2D6
FVSNNSRRARPELAL	PDXP	56	Q96GD0
AFSERIRPEAENKSR	SLX4	446	Q8IY92
PASSEEANRVQRFLS	ADGRD2	551	Q7Z7M1
VFDSNTNRIAAQRPR	CD300A	271	Q9UGN4
RASLAARFQLNPTDT	CIAO3	121	Q9H6Q4
RPFNARLAQVLADEA	CHST15	541	Q7LFX5
RFQEGRVDNIRSATP	CHAT	561	P28329
RAQRRTAAASAVLDP	NCAPD2	461	Q15021
LNRSESPNRERSDFG	CNNM1	736	Q9NRU3
LGRNQEETEPRFSRQ	SPG11	1811	Q96JI7
EPVNAQARKAFSRQR	TSPY9	126	A0A494C1R9
PVNAQARKAFSRQRE	TSPY10	121	P0CW01
PVNAQARKAFSRQRE	TSPY2	121	A6NKD2
EPVNAQARKAFSRQR	TSPY4	126	P0CV99
VSINDRFQQRIFDPR	GGCX	471	P38435
QTSAFARQPRDELER	TMEM175	361	Q9BSA9
PVNAQARKAFSRQRE	TSPY1	121	Q01534
DQERPRSDLSINNRN	MINDY4	31	Q4G0A6
SLARNEAPAFTIDNR	SPO11	61	Q9Y5K1
LLREASARDRQSAQP	TRPV1	796	Q8NER1
QLQPRRVSFRGEASE	PKMYT1	76	Q99640
RFRRQDVRNGDPSTL	SEMA3B	551	Q13214
SNIRPSPFEDLNARR	SPRED1	171	Q7Z699
RTCEQAEDRFRPQSR	THSD1	686	Q9NS62
PNRFDRDRLFNAVSR	TRPV2	71	Q9Y5S1
RDRLFNAVSRGVPED	TRPV2	76	Q9Y5S1
DRDSPRTARQALLTQ	UAP1L1	416	Q3KQV9
VLVSREFADARENRP	WNT3	166	P56703
RDLRQRPASLVVADF	RRP8	301	O43159
PQDAVLSSFRDSRAR	SIGLEC1	1346	Q9BZZ2
AASSASEQRRPRFQA	PRAG1	616	Q86YV5
ALQDFRSRQERTAPA	PHLDA2	106	Q53GA4
PVNAQARKAFSRQRE	TSPY3	121	P0CV98
PVNAQARKAFSRQRE	TSPY8	121	P0CW00
SLQEASSFFQRDRPA	PRR4	111	Q16378
STFVDQQRFSRPRNL	RABAC1	46	Q9UI14
PEFVSRRLLRDNAQA	ZNF251	116	Q9BRH9
SREFADARENRPDAR	WNT3A	166	P56704
QLLRTARDPSEAFQA	TOGARAM1	101	Q9Y4F4
LESQRQVPRSEASAF	RRAS	146	P10301
DELRQCIRNSPQFRF	SMARCA5	971	O60264
LDPFNVSDRRSFLQR	PRSS16	66	Q9NQE7
NRPFSDNSARDSLRI	THEGL	286	P0DJG4
FSVEQRNTRNRENSP	ZNF106	1266	Q9H2Y7
AARQIELDLNRTFPN	TBC1D2	666	Q9BYX2
FINRPNQSRRREDGL	LDLRAD4	96	O15165
RSRDRFTAPSFIQRD	LDLRAD4	136	O15165
NTTRFTRLQDIDPQR	LGI3	311	Q8N145
RDLFNNSRSAVVELP	NACC1	56	Q96RE7
NRTRELRQALQTDPA	MYO9B	1741	Q13459
FSRSRAERQAQEQPR	PPP1R12B	661	O60237