Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	USP_CS	USP51 USP27X	5.35e-03	66	31	2	IPR018200
Domain	USP_1	USP51 USP27X	6.00e-03	70	31	2	PS00972
Domain	UCH	USP51 USP27X	6.17e-03	71	31	2	PF00443
Domain	USP_2	USP51 USP27X	6.17e-03	71	31	2	PS00973
Domain	USP_3	USP51 USP27X	6.34e-03	72	31	2	PS50235
Domain	USP_dom	USP51 USP27X	6.34e-03	72	31	2	IPR028889
Domain	Peptidase_C19_UCH	USP51 USP27X	6.34e-03	72	31	2	IPR001394
Pubmed	Identification, structural characterization, and tissue distribution of Tsg-5: a new TNF-stimulated gene.	HTR2A RB1	2.46e-06	3	32	2	12761567
Pubmed	ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.	USP51 USP27X	4.92e-06	4	32	2	27132940
Pubmed	ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways.	ARID4B RB1	4.92e-06	4	32	2	23487765
Pubmed	Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain.	ARID4B RB1	4.92e-06	4	32	2	17043311
Pubmed	Syntenic assignment of human serotonin receptor subtype 2 (HTR2), esterase D (ESD), and fms-related tyrosine kinase (FLT) homologs to bovine chromosome 12.	HTR2A RB1	4.92e-06	4	32	2	8672130
Pubmed	Comparative linkage mapping of human chromosome 13 and bovine chromosome 12.	HTR2A RB1	8.19e-06	5	32	2	9027485
Pubmed	Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas.	DOCK4 RB1	8.19e-06	5	32	2	19383911
Pubmed	A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.	SYNPO2 ANKRD12 RB1	4.21e-05	73	32	3	22094256
Pubmed	High-resolution genetic mapping of the gunmetal gene which regulates platelet production.	HTR2A RB1	8.55e-05	15	32	2	8833241
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 ZHX3 ARID4B RB1 ZMYM4	2.19e-04	608	32	5	36089195
Pubmed	Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.	CALCOCO2 COPS6	3.75e-04	31	32	2	36114200
Pubmed	The DNA sequence and analysis of human chromosome 13.	HTR2A RB1 DCUN1D2	5.13e-04	170	32	3	15057823
Interaction	CDK6 interactions	CALCOCO2 SYNPO2 ANKRD12 USP51 RB1	2.10e-05	215	32	5	int:CDK6
Cytoband	Ensembl 112 genes in cytogenetic band chrXp11	USP51 H2AP USP27X	2.28e-03	377	32	3	chrXp11
GeneFamily	Ubiquitin specific peptidases	USP51 USP27X	1.91e-03	56	21	2	366
Drug	W-13, hydrochloride; Down 200; 10uM; MCF7; HG-U133A	DNAH3 ANKRD12 COPS6 RB1 BTN2A1	8.26e-06	200	32	5	643_DN
Disease	glioblastoma (implicated_via_orthology)	USP51 USP27X	3.83e-05	9	31	2	DOID:3068 (implicated_via_orthology)
Disease	post-traumatic stress disorder	DOCK4 BTN2A1 ZMYM4	1.23e-03	202	31	3	EFO_0001358
Disease	Colorectal Carcinoma	CALCOCO2 DNAH3 ZMYM4 ABCB4	6.00e-03	702	31	4	C0009402

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSCIAAIQMQNSTKK	TBC1D12	736	O60347
AKNKESLCMENSSNS	ARID4B	846	Q4LE39
TKTCNTMNQFVNKFN	COPS6	296	Q7L5N1
CSKTSFNKENSLTNN	CRYBG3	306	Q68DQ2
NFCIQFKQSKTQLMS	ADH6	111	P28332
NSKQDAKTTDNDCSM	HTR2A	431	P28223
SQTQCQKKETEQMYQ	CCDC144CP	821	Q8IYA2
NTMANQSKQILASCT	ANKRD12	1741	Q6UB98
TSEKFQKINQMVCNS	RB1	841	P06400
RKFSSIQMQLKQSTC	PBX1	206	P40424
MSEKKNCKNSSTNNN	H2AP	1	O75409
QTQSKNNLSFMKTNS	LRRC53	1011	A6NM62
SSQKDKVRQFMACTQ	DCUN1D2	6	Q6PH85
LSCSQQSREMTNKNQ	FSIP2	1456	Q5CZC0
STQKNLKNSQMCQKS	ABCB4	666	P21439
DNNTSHCFNKMTNLK	PARP14	1541	Q460N5
MTCNNSFQDKSLRNS	BICRAL	966	Q6AI39
MCKSSQFKSDQSNPS	CARD6	936	Q9BX69
NNQAMKATKESFCIT	DOCK4	556	Q8N1I0
NMVKETTSNCFKQTI	DNAH3	2326	Q8TD57
DSCISLQKQNSDMQA	CALCOCO2	161	Q13137
NMSCSINNTLLGQKK	BTN2A1	216	Q7KYR7
NSLRQSKASCADMQK	KIF4B	886	Q2VIQ3
MDSADSSSQKQNNKT	KIAA1210	491	Q9ULL0
SGTEMNNKNFSKLCK	TPPP2	21	P59282
SSCSQQFMQKKDLQS	ZBTB48	381	P10074
NSCQSYQESTKQLTM	USP51	571	Q70EK9
SCQSYQESTKQLTMN	USP27X	286	A6NNY8
EACNFMQSSSAKQKT	SYNPO2	741	Q9UMS6
QNLCDKTQMSSQQVK	ZHX3	866	Q9H4I2
QDFKSQKNFIINMTC	TM2D3	111	Q9BRN9
NTNSISTKCSMCQKN	ZMYM4	436	Q5VZL5