Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of cell cycle phase transition

EIF2AK4 ACVR1 EZH2 NSUN2 TP53BP1

3.83e-05311265GO:1901988
GeneOntologyBiologicalProcessnegative regulation of retinoic acid receptor signaling pathway

ZNF536 EZH2

6.83e-0510262GO:0048387
GeneOntologyBiologicalProcessnegative regulation of cell cycle process

EIF2AK4 ACVR1 EZH2 NSUN2 TP53BP1

7.87e-05362265GO:0010948
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

NCOA1 ZNF536 EZH2 UBR5

1.13e-04202264GO:0141193
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

NCOA1 ZNF536 EZH2 UBR5

2.33e-04244264GO:0009755
GeneOntologyBiologicalProcessnegative regulation of cell cycle

EIF2AK4 ACVR1 EZH2 NSUN2 TP53BP1

2.51e-04464265GO:0045786
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

ZNF536 EZH2

3.16e-0421262GO:0048385
GeneOntologyBiologicalProcessregulation of cell cycle phase transition

EIF2AK4 ACVR1 EZH2 NSUN2 TP53BP1

4.09e-04516265GO:1901987
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

1.49e-084303IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

1.49e-084303PF14914
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

1.49e-084303IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

1.49e-084303PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

1.49e-084303IPR015753
DomainCALPONIN_1

TAGLN TAGLN3

3.73e-056302PS01052
DomainCALPONIN_2

TAGLN TAGLN3

3.73e-056302PS51122
DomainCalponin_repeat

TAGLN TAGLN3

3.73e-056302IPR000557
DomainCalponin

TAGLN TAGLN3

3.73e-056302PF00402
DomainSM22_calponin

TAGLN TAGLN3

1.36e-0411302IPR003096
DomainLRR_8

LRRC37A LRRC37A3 LRRC37A2

2.55e-03171303PF13855
DomainLeu-rich_rpt_typical-subtyp

LRRC37A LRRC37A3 LRRC37A2

2.81e-03177303IPR003591
DomainLRR_TYP

LRRC37A LRRC37A3 LRRC37A2

2.81e-03177303SM00369
DomainLRR

LRRC37A LRRC37A3 LRRC37A2

4.02e-03201303PS51450
DomainCH

TAGLN TAGLN3

4.87e-0365302SM00033
DomainLRR_1

LRRC37A LRRC37A3 LRRC37A2

5.11e-03219303PF00560
DomainCH

TAGLN TAGLN3

5.63e-0370302PF00307
Domain-

TAGLN TAGLN3

5.79e-03713021.10.418.10
DomainCH

TAGLN TAGLN3

6.11e-0373302PS50021
DomainCH-domain

TAGLN TAGLN3

6.44e-0375302IPR001715
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

2.32e-09430322419166
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

6.92e-081030323064749
Pubmed

Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22α expression in endothelial cells in response to interleukin-1β and transforming growth factor-β2.

TAGLN EZH2

7.19e-07230225917318
Pubmed

Whole-Exome Sequencing Identifies Novel Recurrent Somatic Mutations in Sporadic Parathyroid Adenomas.

EZH2 ASXL3

2.16e-06330229982334
Pubmed

TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks.

EZH2 TP53BP1

4.31e-06430237002234
Pubmed

Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells.

NCOA1 EZH2

7.18e-06530217502350
Pubmed

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes.

UBR5 TP53BP1

7.18e-06530222884692
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

NHSL1 FAM193A WASHC2A UBR5

3.07e-0520930436779422
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

NCOA1 UBR5 TP53BP1

5.45e-058530316051665
Pubmed

Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.

ACVR1 TAGLN

7.50e-051530231618630
Pubmed

Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.

RNF213 TAGLN

8.57e-051630229859889
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

RNF213 UBR5

1.50e-042130237422473
Pubmed

Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis.

UBR5 TP53BP1

1.50e-042130230179224
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

APLP1 EIF2AK4 UBR5 NSUN2

1.54e-0431730417620599
Pubmed

Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development.

ACVR1 TAGLN

1.80e-042330225759071
Pubmed

Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.

TAGLN EZH2

2.88e-042930228049658
Pubmed

Single-cell atlas of craniogenesis uncovers SOXC-dependent, highly proliferative, and myofibroblast-like osteodermal progenitors.

TAGLN EZH2

3.08e-043030235830813
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

NHSL1 EIF2AK4 NYNRIN

3.11e-0415330310718198
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

CHERP EZH2 UBR5 TP53BP1

3.59e-0439630426687479
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

RNF213 ZNF536 FAM193A CHERP WASHC2A

3.78e-0473330534672954
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF536 WASHC2A UBR5 SNX19

3.98e-0440730412693553
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

CHERP UBR5 TP53BP1

4.01e-0416730325659891
Pubmed

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.

CLCA1 MYBPC1

6.65e-044430226075897
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

NCOA1 EIF2AK4 FAM193A EZH2 UBR5 NSUN2

8.24e-04132730632694731
InteractionTNRC6A interactions

EIF2AK4 FAM193A EZH2 UBR5 NYNRIN TP53BP1

3.06e-06280306int:TNRC6A
InteractionUBE2L3 interactions

NCOA1 RNF213 EZH2 UBR5 TP53BP1

1.38e-05211305int:UBE2L3
Cytoband17q21.31

LRRC37A LRRC37A2

1.33e-038230217q21.31
CytobandEnsembl 112 genes in cytogenetic band chr15q15

EIF2AK4 TP53BP1

4.18e-03147302chr15q15
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A WASHC2A NYNRIN LRRC37A2

4.33e-061643041aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

LRRC37A WASHC2A NYNRIN LRRC37A2

5.23e-06172304fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 LUZP2 ZNF536 TAGLN

6.68e-0618330412daaea821e49bc94a01e2496331e92a80d27339
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 LUZP2 ZNF536 TAGLN

6.98e-061853043b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 LUZP2 ZNF536 TAGLN

6.98e-061853046712512100ccef456d2e2bd201d0987986c92ac9
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 LUZP2 ZNF536 TAGLN

7.91e-0619130408042952431ca1a6fd7dfc13f36eb28643979598
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KIAA0408 LUZP2 ZNF536 TAGLN

8.58e-061953044dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KIAA0408 LUZP2 ZNF536 TAGLN

9.12e-061983042d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal|GW26 / Sample Type, Dataset, Time_group, and Cell type.

APLP1 ZNF536 ASXL3 TAGLN3

9.49e-06200304306926cb7a847871641f02e03d52dc56fd55711c
ToppCellfacs-MAT-Fat-3m-Epithelial-epithelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 CLCA1 MYBPC1

3.33e-05933030d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCellfacs-MAT-Fat-3m-Epithelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 CLCA1 MYBPC1

3.33e-0593303abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCellfacs-MAT-Fat-3m-Epithelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 CLCA1 MYBPC1

3.33e-0593303dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

7.67e-0512330387401764a073c1808f214642a9c84299c78f7ec7
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM124A TAGLN NSUN2

1.20e-0414330339060dc1d87505a16e2df95140087c731f099570
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIAA0408 SNX19 NYNRIN

1.20e-04143303b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LUZP2 ZNF536 MYBPC1

1.86e-0416630359d47c1fca7a8c70f6998f3367a9dbcb9b67966f
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

2.17e-041753031799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LUZP2 ZNF536 MYBPC1

2.29e-041783036ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A LUZP2 TAGLN

2.29e-041783036d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A LUZP2 TAGLN

2.29e-04178303d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.32e-0417930302c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LUZP2 TAGLN3 MYBPC1

2.32e-041793037ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LUZP2 ZNF536 TAGLN

2.40e-0418130325915e2500430a902db37d79a749ce2990b69810
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA0408 ZNF536 TAGLN

2.40e-04181303fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LUZP2 ZNF536 TAGLN

2.40e-04181303d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-7|TCGA-Prostate / Sample_Type by Project: Shred V9

TMEM184A EZH2 NSUN2

2.44e-04182303af16334fec2c757b03c84cf252d00e92fa81e4cd
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA0408 ZNF536 TAGLN

2.48e-0418330361a73de857f4ae02dcba3af348f436f602b28ff2
ToppCelldroplet-Heart-4Chambers-21m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LUZP2 ZNF536 TMEM184A

2.48e-04183303a046b569bc10083d471b420eb2c6fee93437602d
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LUZP2 ZNF536 TAGLN

2.48e-04183303af8d86f15a549064530d94bd47081daf59d58ecd
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LUZP2 ZNF536 TMEM184A

2.48e-041833034de2082dca2569d3aac3c9b466f27971c82d302b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0408 ZAN ASXL3

2.52e-04184303ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0408 ZAN ASXL3

2.52e-041843032cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0408 ZAN ASXL3

2.52e-041843032b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APLP1 LUZP2 TAGLN3

2.52e-04184303abb61e744a9031e0c91eb560a8f486a0ca5a01cc
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 CLCA1 TAGLN3

2.56e-041853033a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.56e-04185303e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCelldroplet-Heart-nan-18m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LUZP2 ZNF536 TMEM184A

2.56e-04185303c61267cfadea018794f7964904445787629a40d1
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LUZP2 ZNF536 TMEM184A

2.56e-041853033a592719d5643011954f89d5bb61a5e94682b68e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APLP1 LUZP2 TAGLN3

2.56e-04185303edb114487206e4e8df4c7878285df40f49b7fd64
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NHSL1 CLCA1 TAGLN3

2.56e-04185303224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.60e-041863036add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LUZP2 ZNF536 TAGLN

2.64e-04187303c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LUZP2 ZNF536 TAGLN

2.68e-04188303c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LUZP2 ZNF536 TAGLN

2.68e-041883034d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.68e-041883033177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LUZP2 ZNF536 TAGLN

2.68e-04188303f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 UBR5 NYNRIN

2.68e-041883036468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 UBR5 NYNRIN

2.68e-041883037a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 UBR5 NYNRIN

2.68e-041883039cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellfacs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 TAGLN MYBPC1

2.68e-04188303794fc1d9a726945c42f7eac221eed938309b47a9
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.68e-04188303293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FAM124A ZNF536 TAGLN

2.68e-041883033004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FAM124A ZNF536 TAGLN

2.72e-04189303f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellNeuronal_cells-Schwann_cells|World / Lineage and Cell class

APLP1 LUZP2 ZNF536

2.72e-04189303371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCellNeuronal_cells|World / Lineage and Cell class

APLP1 LUZP2 ZNF536

2.72e-041893033948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.72e-041893037ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NHSL1 CLCA1 TAGLN3

2.77e-04190303a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM124A ZNF536 TAGLN

2.77e-04190303c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

LUZP2 ZNF536 TAGLN

2.77e-04190303645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 LUZP2 TAGLN3

2.77e-04190303e792e42fc49472eaf974eb0905819eb51a1da8e5
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NHSL1 CLCA1 TAGLN3

2.77e-0419030357c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NHSL1 CLCA1 TAGLN3

2.77e-04190303f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIAA0408 TAGLN MYBPC1

2.77e-04190303799351fea7490d4159271d020c43c845ef37c788
ToppCell5'-Adult-LymphNode-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 NYNRIN TP53BP1

2.81e-04191303e5c41c3054ead03597c136eaccaf9822e6bb9d1a
ToppCell5'-Adult-LymphNode-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLCA1 NYNRIN TP53BP1

2.81e-041913037e24175c7fabe5ea0b22b73173da4c3a666e5eb8
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LUZP2 ZNF536 TAGLN3

2.81e-04191303a53616c84178eb6c29b48662358765b082df3f97
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM124A CLCA1 NYNRIN

2.85e-041923035890076929598e88fe9d59a4e4e858b446746ce9
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 ZNF536 TAGLN

2.85e-04192303992d08092edbc68c47b945deb8708379738c239a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA0408 LUZP2 ZNF536

2.85e-0419230363d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APLP1 FAM124A ZNF536

2.85e-041923033ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCellwk_15-18-Epithelial-PNS|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

APLP1 ZNF536 TAGLN3

2.90e-04193303ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LUZP2 ZNF536 TAGLN

2.90e-04193303146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIAA0408 APLP1 FAM124A

2.90e-04193303947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FAM124A ZNF536 TAGLN

2.90e-04193303516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

2.94e-0419430391205b22650e7ecdb72bb59348ce2530b76c532c
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NHSL1 CLCA1 TAGLN

2.94e-041943032f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

2.94e-041943038fae8061b350336299aa81f378e07deadbd55123
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

UBR5 TP53BP1 LRRC37A2

2.94e-0419430388db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

UBR5 TP53BP1 LRRC37A2

2.94e-04194303a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

2.94e-041943034d7d24390fdb379f943ddcc70a63f23955e10163
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

2.94e-041943036e12a7da35be4c0ecf998ef94b8989b89d74b200
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

2.94e-04194303c52f10140c66e8c0566421c3d535d5d92bf595e1
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LUZP2 ZNF536 TAGLN

2.99e-04195303eb2003d4f15cad213d17eda8ab7479f5a0c62164
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LUZP2 ZNF536 TAGLN

2.99e-0419530344f67437ea65d530133a0240b17f9860d9cc0e99
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APLP1 ZNF536 TAGLN3

3.03e-04196303eea354bdaf4c558df6a94ec4f2f817f7073821d9
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

APLP1 ZNF536 TAGLN

3.08e-04197303378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LUZP2 ZNF536 TAGLN

3.08e-0419730316758f181ef07c60aee63072e1da9572c5c85414
ToppCellwk_08-11-Epithelial-PNS|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

APLP1 ZNF536 TAGLN3

3.08e-04197303ce3f9feb6935f0e9daf13673b0a0d6e92817e187
ToppCellproximal-mesenchymal-Myofibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LUZP2 ZNF536 TAGLN

3.08e-04197303ab21baea931ff134cf5a7ee369c091230988108b
ToppCellproximal-mesenchymal-Myofibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LUZP2 ZNF536 TAGLN

3.08e-0419730315f2f169758a07143fc7d1bdb58d0b4d750a0be4
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

APLP1 ZNF536 TAGLN

3.08e-04197303079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

APLP1 LUZP2 TAGLN3

3.08e-04197303b9478212f14b7888e3abac02995177974ac3bd17
ToppCellP07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

APLP1 ZNF536 TAGLN

3.08e-04197303b1135378d768fbbe62a75747d1e8653d35252187
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

APLP1 FAM124A ZNF536

3.08e-0419730382b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellproximal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LUZP2 ZNF536 TAGLN

3.08e-04197303c59b64674fb4aaa945c1df7e4a9a3605c7cd2b75
ToppCellP03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

APLP1 ZNF536 TAGLN

3.08e-041973032cec938caf6ffd031cea37277071487e59b2c71c
ToppCelldistal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LUZP2 ZNF536 TAGLN

3.12e-04198303dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

NHSL1 NCOA1 LRRC37A3

3.12e-041983031996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APLP1 LUZP2 ZNF536

3.12e-04198303731a90f7e68b19e387499d63e3979af78b503b0c
ToppCelldistal-mesenchymal-Fibromyocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LUZP2 ZNF536 TAGLN

3.12e-041983039d1d95e7703cfc70a8ad427e400c340dbd205db8
DiseaseMammary Neoplasms, Human

NCOA1 ACVR1 LRRC37A EZH2 TP53BP1 LRRC37A2

1.03e-05525296C1257931
DiseaseMammary Carcinoma, Human

NCOA1 ACVR1 LRRC37A EZH2 TP53BP1 LRRC37A2

1.03e-05525296C4704874
DiseaseMammary Neoplasms

NCOA1 ACVR1 LRRC37A EZH2 TP53BP1 LRRC37A2

1.06e-05527296C1458155
DiseaseBreast Carcinoma

NCOA1 ACVR1 LRRC37A EZH2 TP53BP1 LRRC37A2

1.19e-05538296C0678222
Diseaseasymmetrical dimethylarginine measurement, serum dimethylarginine measurement

ZNF536 CLCA1

4.83e-0433292EFO_0005418, EFO_0006522
Diseaseglucose measurement

ACVR1 LRRC37A ZAN LRRC37A3

4.98e-04380294EFO_0004468
DiseaseMalignant neoplasm of breast

NCOA1 ACVR1 LRRC37A EZH2 TP53BP1 LRRC37A2

5.31e-041074296C0006142
Diseaselipoprotein-associated phospholipase A(2) measurement

RNF213 TP53BP1

7.11e-0440292EFO_0004746
Diseaseantibody measurement

ZNF536 ASXL3

1.07e-0349292EFO_0004556
DiseaseNasal Cavity Polyp

NCOA1 LUZP2

1.34e-0355292EFO_1000391
Diseasecolon cancer (is_marker_for)

EZH2 UBR5

1.54e-0359292DOID:219 (is_marker_for)
Diseasehistidine measurement

NYNRIN TP53BP1

1.92e-0366292EFO_0009769
DiseaseS-warfarin measurement

NHSL1 EIF2AK4

4.10e-0397292EFO_0803323
Diseasecorneal topography

NHSL1 EIF2AK4

5.14e-03109292EFO_0004345
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

NYNRIN TP53BP1

5.33e-03111292EFO_0004530, EFO_0008595

Protein segments in the cluster

PeptideGeneStartEntry
PQPKMPLVEQSPEDS

EIF2AK4

541

Q9P2K8
LPSPSMEDEKPKVNP

ACVR1

16

Q04771
QPPDSKDDTPMTLPK

APLP1

511

P51693
KDEKSNPTPMEPTSP

FAM193A

1116

P78312
PSDQKQPPVTMETTK

ASXL3

2051

Q9C0F0
TQIRPTMFPPKDPEK

NSUN2

386

Q08J23
TMKETPTQPPKKVVP

LRRC37A3

566

O60309
TMKETPTQPPKKVVP

LRRC37A2

566

A6NM11
TMKETPTQPPKKVVP

LRRC37A

566

A6NMS7
DTPKVKQTDGDMPPP

FAM124A

516

Q86V42
MVQPDVSPAPKQEEP

NHSL1

1286

Q5SYE7
TPIKMKPNIEPPENV

EZH2

416

Q15910
MPVPMENVPDNPTKK

KIAA0408

501

Q6ZU52
PPTTQPDDSKPPIQM

CHERP

371

Q8IWX8
ETEPIPQKLQMPPCS

LUZP2

306

Q86TE4
QPPKMTKPETPEETQ

SAMD15

231

Q9P1V8
QVEPTTPKTPQAQKM

NYNRIN

616

Q9P2P1
PPGQEPIPKISESKM

TAGLN3

71

Q9UI15
EKKENSPAPPAPMQS

TMEM184A

331

Q6ZMB5
TNPTPMTKPTPEEIK

NCOA1

786

Q15788
PVKVPENPPSMVFKQ

TAGLN

76

Q01995
DFKKTTPMTTQPPNP

CLCA1

281

A8K7I4
EKTQRMKQPPATTPP

RNF213

291

Q63HN8
SQQPMKPISPVKDPV

TP53BP1

1086

Q12888
EMQPTKAPEKDPEQP

SNX19

776

Q92543
VKNKSPSDPEVPVPM

ZNF536

401

O15090
SMKEPQKPEQPTPRK

WASHC2A

426

Q641Q2
PESKQEPVKTEMGPP

UBR5

596

O95071
STEKPTIPSEKPNMP

ZAN

601

Q9Y493
TIPSEKPNMPSEKPT

ZAN

606

Q9Y493
KPNMPSEKPTIPSEK

ZAN

611

Q9Y493
MPEPTKKEENEVPAP

MYBPC1

1

Q00872