Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlipid transporter activity

ABCC3 ABCA2 CEACAM5 PSG3 PSG11 NPC1L1 STRA6 ATP10A ATP8B2 CEACAM1

1.09e-081968510GO:0005319
GeneOntologyMolecularFunctionToll-like receptor binding

CEACAM5 PSG3 PSG11 TLR2 CEACAM1

1.36e-0729855GO:0035325
GeneOntologyMolecularFunctiongranulocyte colony-stimulating factor receptor binding

CEACAM5 PSG3 PSG11 CEACAM1

2.96e-0714854GO:0005130
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

ABCC3 CEACAM5 PSG3 PSG11 CEACAM1

3.13e-0734855GO:0015125
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

ABCC3 CEACAM5 PSG3 PSG11 STRA6 CEACAM1

5.25e-0770856GO:1901618
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC3 CEACAM5 PSG3 PSG11 STRA6 CEACAM1

6.74e-0773856GO:0170055
GeneOntologyMolecularFunctionGPI anchor binding

CEACAM5 PSG3 PSG11 CEACAM1

2.55e-0623854GO:0034235
GeneOntologyMolecularFunctionfilamin binding

CEACAM5 PSG3 PSG11 CEACAM1

6.70e-0629854GO:0031005
GeneOntologyMolecularFunctionfloppase activity

ABCA2 ATP10A ATP8B2

4.01e-0516853GO:0140328
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

ABCC3 CEACAM5 PSG3 PSG11 CEACAM1

4.11e-0590855GO:0008028
GeneOntologyMolecularFunctionglycolipid binding

CEACAM5 PSG3 PSG11 CEACAM1

5.60e-0549854GO:0051861
GeneOntologyMolecularFunctiontransporter activity

ABCC3 CACNA2D4 ABCA2 CEACAM5 PSG3 PSG11 NPC1L1 SLC28A1 STRA6 PKD1L2 PKD1L3 SLC22A24 ATP10A TAP2 ATP8B2 CEACAM1

9.43e-0512898516GO:0005215
GeneOntologyMolecularFunctiongrowth factor receptor binding

KL CEACAM5 PSG3 PSG11 TLR9 CEACAM1

9.63e-05173856GO:0070851
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA2 ATP10A ATP8B2

2.26e-0428853GO:0140326
GeneOntologyMolecularFunctionphosphatidylcholine flippase activity

ATP10A ATP8B2

2.66e-046852GO:0140345
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

CEACAM5 PSG3 PSG11 CEACAM3 CEACAM1

4.39e-04149855GO:1990782
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ATP10A ATP8B2

4.93e-048852GO:0090554
GeneOntologyMolecularFunctionubiquitin conjugating enzyme activity

UBE2NL UBE2D2 UBE2D3

5.21e-0437853GO:0061631
GeneOntologyMolecularFunctioncomplement component C1q complex binding

C4A C4B

7.88e-0410852GO:0001849
GeneOntologyMolecularFunctionubiquitin-like protein conjugating enzyme activity

UBE2NL UBE2D2 UBE2D3

8.12e-0443853GO:0061650
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCA2 TAP2

1.19e-0349853GO:0140359
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA2 ATP10A ATP8B2

1.34e-0351853GO:0140303
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCC3 CACNA2D4 ABCA2 CEACAM5 PSG3 PSG11 SLC28A1 STRA6 PKD1L2 PKD1L3 SLC22A24 TAP2 CEACAM1

1.40e-0311808513GO:0022857
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP10A ATP8B2

1.58e-0314852GO:0140333
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

ABCC3 CEACAM5 PSG3 PSG11 CEACAM1

1.91e-03207855GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

ABCC3 CEACAM5 PSG3 PSG11 CEACAM1

1.95e-03208855GO:0005342
GeneOntologyMolecularFunctionprotein phosphatase binding

CEACAM5 PSG3 PSG11 SMG5 CEACAM1

2.04e-03210855GO:0019903
GeneOntologyMolecularFunctioncarbohydrate binding

MAN2C1 C4A C4B PKD1L2 PKD1L3 FREM1

2.09e-03310856GO:0030246
GeneOntologyMolecularFunctionflippase activity

ATP10A ATP8B2

2.34e-0317852GO:0140327
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 ABCA2 DYNC2H1 ATP10A TAP2 ATP8B2 KIFC2

2.74e-03441857GO:0016887
GeneOntologyMolecularFunctioncalmodulin binding

CEACAM5 PSG3 PSG11 UBR4 CEACAM1

3.02e-03230855GO:0005516
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCA2 ATP10A

3.24e-0320852GO:0046624
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ATP10A ATP8B2

3.24e-0320852GO:0008525
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

KL MAN2C1 GLB1L3 TLR2

3.34e-03144854GO:0016798
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 ABCA2 DYNC2H1 NAE1 ATP10A TAP2 ATP8B2 KIFC2

4.60e-03614858GO:0140657
GeneOntologyMolecularFunctiontelomerase RNA binding

SMG5 TEP1

5.04e-0325852GO:0070034
GeneOntologyMolecularFunctionopsonin binding

C4A C4B

5.04e-0325852GO:0001846
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity directed against tumor cell target

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

3.55e-0823865GO:0002858
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immune response to tumor cell

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

4.47e-0824865GO:0002855
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity directed against tumor cell target

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

4.47e-0824865GO:0002420
GeneOntologyBiologicalProcessnatural killer cell mediated immune response to tumor cell

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

5.57e-0825865GO:0002423
GeneOntologyBiologicalProcessnegative regulation of platelet activation

CEACAM5 PSG3 PSG11 CEACAM1 GP5

1.75e-0731865GO:0010544
GeneOntologyBiologicalProcessnegative regulation of brown fat cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

2.73e-0714864GO:0070348
GeneOntologyBiologicalProcessregulation of brown fat cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

3.71e-0715864GO:0070347
GeneOntologyBiologicalProcesspositive regulation of homophilic cell adhesion

CEACAM5 PSG3 PSG11 CEACAM1

3.71e-0715864GO:1903387
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immune response to tumor cell

CEACAM5 PSG3 PSG11 CEACAM1

3.71e-0715864GO:0002856
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

CEACAM5 PSG3 PSG11 CEACAM1

3.71e-0715864GO:0002859
GeneOntologyBiologicalProcessinsulin receptor internalization

CEACAM5 PSG3 PSG11 CEACAM1

4.93e-0716864GO:0038016
GeneOntologyBiologicalProcessnegative regulation of fatty acid biosynthetic process

CEACAM5 PSG3 PSG11 UBR4 CEACAM1

5.77e-0739865GO:0045717
GeneOntologyBiologicalProcessbrown fat cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

6.43e-0717864GO:0070342
GeneOntologyBiologicalProcessinsulin catabolic process

CEACAM5 PSG3 PSG11 CEACAM1

6.43e-0717864GO:1901143
GeneOntologyBiologicalProcessgranulocyte colony-stimulating factor signaling pathway

CEACAM5 PSG3 PSG11 CEACAM1

6.43e-0717864GO:0038158
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

6.57e-0740865GO:0045953
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

7.46e-0741865GO:0002716
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

7.62e-0776866GO:0042269
GeneOntologyBiologicalProcessregulation of homophilic cell adhesion

CEACAM5 PSG3 PSG11 CEACAM1

8.24e-0718864GO:1903385
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immunity

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

1.03e-0680866GO:0002715
GeneOntologyBiologicalProcessnegative regulation of hepatocyte proliferation

CEACAM5 PSG3 PSG11 CEACAM1

1.30e-0620864GO:2000346
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated cytotoxicity

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

1.50e-0647865GO:0001911
GeneOntologyBiologicalProcessbile acid and bile salt transport

ABCC3 CEACAM5 PSG3 PSG11 CEACAM1

1.50e-0647865GO:0015721
GeneOntologyBiologicalProcessnegative regulation of fat cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

1.60e-0621864GO:0070345
GeneOntologyBiologicalProcessnegative regulation of response to tumor cell

CEACAM5 PSG3 PSG11 CEACAM1

1.60e-0621864GO:0002835
GeneOntologyBiologicalProcessnegative regulation of immune response to tumor cell

CEACAM5 PSG3 PSG11 CEACAM1

1.60e-0621864GO:0002838
GeneOntologyBiologicalProcessregulation of immune response to tumor cell

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

1.85e-0649865GO:0002837
GeneOntologyBiologicalProcessnegative regulation of granulocyte differentiation

CEACAM5 PSG3 PSG11 CEACAM1

1.95e-0622864GO:0030853
GeneOntologyBiologicalProcessregulation of response to tumor cell

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

2.05e-0650865GO:0002834
GeneOntologyBiologicalProcessnegative regulation of lipid biosynthetic process

ABCA2 CEACAM5 PSG3 PSG11 UBR4 CEACAM1

2.21e-0691866GO:0051055
GeneOntologyBiologicalProcessnegative regulation of platelet aggregation

CEACAM5 PSG3 PSG11 CEACAM1

2.35e-0623864GO:0090331
GeneOntologyBiologicalProcessnegative regulation of cell killing

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

2.50e-0652865GO:0031342
GeneOntologyBiologicalProcesspositive regulation of vasculogenesis

CEACAM5 PSG3 PSG11 CEACAM1

2.81e-0624864GO:2001214
GeneOntologyBiologicalProcesscommon myeloid progenitor cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

3.33e-0625864GO:0035726
GeneOntologyBiologicalProcessimmune response to tumor cell

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

3.62e-0656865GO:0002418
GeneOntologyBiologicalProcesslipid localization

ABCC3 ABCA2 CEACAM5 MOSPD2 PSG3 PSG11 NPC1L1 STRA6 SLC22A24 ATP10A ATP8B2 CEACAM1

3.84e-065658612GO:0010876
GeneOntologyBiologicalProcessregulation of fat cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

4.59e-0627864GO:0070344
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

5.09e-06105866GO:0042267
GeneOntologyBiologicalProcessnegative regulation of fatty acid metabolic process

CEACAM5 PSG3 PSG11 UBR4 CEACAM1

5.11e-0660865GO:0045922
GeneOntologyBiologicalProcessnegative regulation of homotypic cell-cell adhesion

CEACAM5 PSG3 PSG11 CEACAM1

5.34e-0628864GO:0034111
GeneOntologyBiologicalProcessregulation of vasculogenesis

CEACAM5 PSG3 PSG11 CEACAM1

6.18e-0629864GO:2001212
GeneOntologyBiologicalProcessnatural killer cell mediated immunity

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

6.32e-06109866GO:0002228
GeneOntologyBiologicalProcesslipid transport

ABCC3 ABCA2 CEACAM5 PSG3 PSG11 NPC1L1 STRA6 SLC22A24 ATP10A ATP8B2 CEACAM1

8.09e-065068611GO:0006869
GeneOntologyBiologicalProcessregulation of platelet activation

CEACAM5 PSG3 PSG11 CEACAM1 GP5

8.20e-0666865GO:0010543
GeneOntologyBiologicalProcessdetection of stimulus

NR2F6 OR11L1 CACNA2D4 TLR2 CRTAM OR2W5P GPR52 C4B TLR9 PKD1L2 PKD1L3 PPEF1 WDR47

8.79e-067228613GO:0051606
GeneOntologyBiologicalProcessregulation of endothelial cell differentiation

CEACAM5 PSG3 PSG11 BTG1 CEACAM1

8.83e-0667865GO:0045601
GeneOntologyBiologicalProcessnegative regulation of bone resorption

CEACAM5 PSG3 PSG11 CEACAM1

9.27e-0632864GO:0045779
GeneOntologyBiologicalProcessfat cell proliferation

CEACAM5 PSG3 PSG11 CEACAM1

9.27e-0632864GO:0070341
GeneOntologyBiologicalProcessregulation of blood vessel remodeling

CEACAM5 PSG3 PSG11 CEACAM1

9.27e-0632864GO:0060312
GeneOntologyBiologicalProcessnegative regulation of blood coagulation

CEACAM5 PSG3 PSG11 CEACAM1 GP5

1.02e-0569865GO:0030195
GeneOntologyBiologicalProcessregulation of granulocyte differentiation

CEACAM5 PSG3 PSG11 CEACAM1

1.05e-0533864GO:0030852
GeneOntologyBiologicalProcessnegative regulation of feeding behavior

CEACAM5 PSG3 PSG11 CEACAM1

1.05e-0533864GO:2000252
GeneOntologyBiologicalProcessnegative regulation of hemostasis

CEACAM5 PSG3 PSG11 CEACAM1 GP5

1.10e-0570865GO:1900047
GeneOntologyBiologicalProcessresponse to tumor cell

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

1.17e-0571865GO:0002347
GeneOntologyBiologicalProcessnegative regulation of vascular permeability

CEACAM5 PSG3 PSG11 CEACAM1

1.19e-0534864GO:0043116
GeneOntologyBiologicalProcessnegative regulation of bone remodeling

CEACAM5 PSG3 PSG11 CEACAM1

1.19e-0534864GO:0046851
GeneOntologyBiologicalProcessnegative regulation of coagulation

CEACAM5 PSG3 PSG11 CEACAM1 GP5

1.26e-0572865GO:0050819
GeneOntologyBiologicalProcessregulation of leukocyte mediated cytotoxicity

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

1.33e-05124866GO:0001910
GeneOntologyBiologicalProcessinsulin metabolic process

CEACAM5 PSG3 PSG11 CEACAM1

1.34e-0535864GO:1901142
GeneOntologyBiologicalProcessregulation of fatty acid biosynthetic process

CEACAM5 PSG3 PSG11 UBR4 CEACAM1

1.35e-0573865GO:0042304
GeneOntologyBiologicalProcessorganic hydroxy compound transport

ABCC3 ABCA2 CEACAM5 PSG3 PSG11 NPC1L1 STRA6 SLC22A24 CEACAM1

1.83e-05358869GO:0015850
GeneOntologyBiologicalProcessregulation of hepatocyte proliferation

CEACAM5 PSG3 PSG11 CEACAM1

1.87e-0538864GO:2000345
GeneOntologyBiologicalProcessprotein K27-linked ubiquitination

UBE2D2 UBE2D3 UBR4

2.46e-0514863GO:0044314
GeneOntologyBiologicalProcessnegative regulation of lymphocyte mediated immunity

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

2.52e-0583865GO:0002707
GeneOntologyBiologicalProcessregulation of platelet aggregation

CEACAM5 PSG3 PSG11 CEACAM1

2.79e-0542864GO:0090330
GeneOntologyBiologicalProcessnegative regulation of lipid metabolic process

ABCA2 CEACAM5 PSG3 PSG11 UBR4 CEACAM1

3.22e-05145866GO:0045833
GeneOntologyBiologicalProcessregulation of cell killing

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

3.48e-05147866GO:0031341
GeneOntologyBiologicalProcessnegative regulation of behavior

CEACAM5 PSG3 PSG11 CEACAM1

3.68e-0545864GO:0048521
GeneOntologyBiologicalProcessdetection of molecule of bacterial origin

TLR2 C4B TLR9

3.77e-0516863GO:0032490
GeneOntologyBiologicalProcessregulation of blood coagulation

CEACAM5 PSG3 PSG11 CEACAM1 GP5

3.93e-0591865GO:0030193
GeneOntologyBiologicalProcessepithelial cell proliferation involved in liver morphogenesis

CEACAM5 PSG3 PSG11 CEACAM1

4.02e-0546864GO:0072575
GeneOntologyBiologicalProcesshepatocyte proliferation

CEACAM5 PSG3 PSG11 CEACAM1

4.02e-0546864GO:0072574
GeneOntologyBiologicalProcessdetection of biotic stimulus

TLR2 CRTAM C4B TLR9

4.02e-0546864GO:0009595
GeneOntologyBiologicalProcessregulation of hemostasis

CEACAM5 PSG3 PSG11 CEACAM1 GP5

4.36e-0593865GO:1900046
GeneOntologyBiologicalProcessnegative regulation of tissue remodeling

CEACAM5 PSG3 PSG11 CEACAM1

4.38e-0547864GO:0034104
GeneOntologyBiologicalProcessregulation of leukocyte mediated immunity

CEACAM5 PSG3 PSG11 TLR2 CRTAM TLR9 TAP2 CEACAM1

4.46e-05309868GO:0002703
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated immunity

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

5.08e-0596865GO:0002704
GeneOntologyBiologicalProcessregulation of coagulation

CEACAM5 PSG3 PSG11 CEACAM1 GP5

5.08e-0596865GO:0050818
GeneOntologyBiologicalProcessliver morphogenesis

CEACAM5 PSG3 PSG11 CEACAM1

5.17e-0549864GO:0072576
GeneOntologyBiologicalProcessnegative regulation of wound healing

CEACAM5 PSG3 PSG11 CEACAM1 GP5

5.61e-0598865GO:0061045
GeneOntologyBiologicalProcessregulation of homotypic cell-cell adhesion

CEACAM5 PSG3 PSG11 CEACAM1

7.06e-0553864GO:0034110
GeneOntologyBiologicalProcessnegative regulation of T cell proliferation

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

8.53e-05107865GO:0042130
GeneOntologyBiologicalProcessdetection of external stimulus

NR2F6 CACNA2D4 GPR52 PKD1L2 PKD1L3 WDR47

8.62e-05173866GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

NR2F6 CACNA2D4 GPR52 PKD1L2 PKD1L3 WDR47

9.18e-05175866GO:0009582
GeneOntologyBiologicalProcessnegative regulation of osteoclast differentiation

CEACAM5 PSG3 PSG11 CEACAM1

1.08e-0459864GO:0045671
GeneOntologyBiologicalProcessgranulocyte differentiation

CEACAM5 PSG3 PSG11 CEACAM1

1.15e-0460864GO:0030851
GeneOntologyBiologicalProcessnegative regulation of innate immune response

CEACAM5 PSG3 PSG11 TAP2 CEACAM1

1.15e-04114865GO:0045824
GeneOntologyBiologicalProcessnegative regulation of cell activation

CEACAM5 FN1 PSG3 PSG11 CRTAM CEACAM1 GP5

1.18e-04264867GO:0050866
GeneOntologyBiologicalProcessregulation of feeding behavior

CEACAM5 PSG3 PSG11 CEACAM1

1.23e-0461864GO:0060259
GeneOntologyBiologicalProcesspositive regulation of MAPK cascade

RAF1 LPAR3 KL CEACAM5 PSG3 PSG11 NTRK3 TLR2 TLR9 CEACAM1

1.31e-045718610GO:0043410
GeneOntologyBiologicalProcessleukocyte mediated cytotoxicity

CEACAM5 PSG3 PSG11 CRTAM TAP2 CEACAM1

1.32e-04187866GO:0001909
GeneOntologyBiologicalProcessleukocyte mediated immunity

CEACAM5 PSG3 PSG11 TLR2 CRTAM C4A C4B TLR9 TAP2 CEACAM1

1.41e-045768610GO:0002443
GeneOntologyBiologicalProcessnegative regulation of lymphocyte proliferation

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

1.71e-04124865GO:0050672
GeneOntologyBiologicalProcessnegative regulation of response to wounding

CEACAM5 PSG3 PSG11 CEACAM1 GP5

1.84e-04126865GO:1903035
GeneOntologyBiologicalProcessnegative regulation of mononuclear cell proliferation

CEACAM5 PSG3 PSG11 CRTAM CEACAM1

1.84e-04126865GO:0032945
GeneOntologyBiologicalProcessregulation of behavior

CEACAM5 PSG3 PSG11 STRA6 CEACAM1

1.98e-04128865GO:0050795
GeneOntologyBiologicalProcessregulation of ERK1 and ERK2 cascade

CEACAM5 FN1 PSG3 PSG11 NTRK3 TLR2 TLR9 CEACAM1

2.04e-04385868GO:0070372
GeneOntologyBiologicalProcesspositive regulation of MAP kinase activity

CEACAM5 PSG3 PSG11 NTRK3 CEACAM1

2.06e-04129865GO:0043406
GeneOntologyBiologicalProcessregulation of bone resorption

CEACAM5 PSG3 PSG11 CEACAM1

2.09e-0470864GO:0045124
GeneOntologyBiologicalProcessregulation of vascular permeability

CEACAM5 PSG3 PSG11 CEACAM1

2.21e-0471864GO:0043114
GeneOntologyCellularComponenttransforming growth factor beta ligand-receptor complex

CEACAM5 PSG3 PSG11 CEACAM1

4.46e-0716854GO:0070021
GeneOntologyCellularComponentapical part of cell

KL CEACAM5 FN1 PSG3 DYNC2H1 PSG11 NPC1L1 SLC28A1 TLR9 ENPEP CEACAM1

2.74e-055928511GO:0045177
GeneOntologyCellularComponentapical plasma membrane

KL CEACAM5 FN1 PSG3 PSG11 NPC1L1 SLC28A1 TLR9 ENPEP CEACAM1

2.82e-054878510GO:0016324
GeneOntologyCellularComponentciliary membrane

CEACAM5 PSG3 PSG11 CEACAM1 TCTN2

4.98e-0598855GO:0060170
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC3 CEACAM5 PSG3 PSG11 TLR9 MAP7 CEACAM1

3.28e-04320857GO:0016323
GeneOntologyCellularComponentcell projection membrane

CEACAM5 PSG3 PSG11 NPC1L1 SLC28A1 ENPEP CEACAM1 TCTN2

3.68e-04431858GO:0031253
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

CEACAM5 PSG3 PIK3C2G PSG11 POLR2A INSRR CEACAM1

4.32e-04335857GO:0061695
GeneOntologyCellularComponentsymbiont cell surface

C4A C4B

4.50e-048852GO:0106139
GeneOntologyCellularComponentlateral plasma membrane

CEACAM5 PSG3 PSG11 CEACAM1

4.99e-0490854GO:0016328
GeneOntologyCellularComponentspecific granule membrane

MOSPD2 UBR4 CEACAM3 CEACAM1

5.20e-0491854GO:0035579
GeneOntologyCellularComponentplasma membrane signaling receptor complex

CEACAM5 PSG3 PSG11 TLR2 INSRR CEACAM1 GP5

5.60e-04350857GO:0098802
GeneOntologyCellularComponentother organism part

C4A C4B

5.77e-049852GO:0044217
GeneOntologyCellularComponentreceptor complex

CEACAM5 PSG3 PSG11 NTRK3 TLR2 INSRR PKD1L3 CEACAM1 GP5

5.86e-04581859GO:0043235
GeneOntologyCellularComponentbasal plasma membrane

ABCC3 CEACAM5 PSG3 PSG11 TLR9 MAP7 CEACAM1

5.99e-04354857GO:0009925
GeneOntologyCellularComponentprotein kinase complex

CEACAM5 PSG3 PSG11 INSRR CEACAM1

6.51e-04170855GO:1902911
GeneOntologyCellularComponentbasal part of cell

ABCC3 CEACAM5 PSG3 PSG11 TLR9 MAP7 CEACAM1

8.80e-04378857GO:0045178
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP10A ATP8B2

1.44e-0314852GO:1990531
GeneOntologyCellularComponentblood microparticle

FN1 C4A C4B CPN2

2.84e-03144854GO:0072562
GeneOntologyCellularComponentserine/threonine protein kinase complex

CEACAM5 PSG3 PSG11 CEACAM1

3.87e-03157854GO:1902554
GeneOntologyCellularComponentspecific granule

MOSPD2 UBR4 CEACAM3 CEACAM1

4.14e-03160854GO:0042581
GeneOntologyCellularComponentT cell receptor complex

CEACAM5 PSG3 PSG11 CEACAM1

4.42e-03163854GO:0042101
GeneOntologyCellularComponentplasma membrane protein complex

CACNA2D4 ABCA2 CEACAM5 PSG3 PSG11 TLR2 INSRR CEACAM1 GP5

4.57e-03785859GO:0098797
GeneOntologyCellularComponenttelomerase holoenzyme complex

SMG5 TEP1

4.61e-0325852GO:0005697
GeneOntologyCellularComponentbrush border membrane

NPC1L1 SLC28A1 ENPEP

4.72e-0383853GO:0031526
GeneOntologyCellularComponentendocytic vesicle

NLGN3 TLR2 TLR9 HEATR5B TAP2 KIFC2

4.78e-03384856GO:0030139
GeneOntologyCellularComponentcell surface

NLGN3 CEACAM5 PSG3 PSG11 TLR2 CEACAM3 IL17RC PKD1L3 ENPEP CEACAM1 GP5

5.27e-0311118511GO:0009986
GeneOntologyCellularComponenttransferase complex

CEACAM5 UBE2D2 UBE2D3 PELP1 PSG3 PIK3C2G PSG11 POLR2A INSRR CEACAM1

5.63e-039638510GO:1990234
MousePhenodecreased susceptibility to Coronaviridae infection

CEACAM5 PSG3 PSG11 C4A C4B CEACAM1

5.66e-0928736MP:0020950
MousePhenoabnormal susceptibility to Coronaviridae infection

CEACAM5 PSG3 PSG11 C4A C4B CEACAM1

1.93e-0749736MP:0020948
MousePhenodecreased susceptibility to Coronaviridae infection induced morbidity/mortality

CEACAM5 PSG3 PSG11 CEACAM1

1.55e-0617734MP:0031047
MousePhenoincreased skeletal muscle triglyceride level

CEACAM5 PSG3 PSG11 CEACAM1

3.83e-0621734MP:0031415
MousePhenodecreased susceptibility to viral infection

CEACAM5 PSG3 PSG11 TLR2 C4A C4B CEACAM1

3.86e-06125737MP:0002410
MousePhenodecreased susceptibility to Riboviria infection

CEACAM5 PSG3 PSG11 C4A C4B CEACAM1

4.21e-0682736MP:0020914
MousePhenodecreased fatty acid oxidation

CEACAM5 PSG3 PSG11 CEACAM1

6.72e-0624734MP:0014172
MousePhenoabnormal fatty acid oxidation

CEACAM5 PSG3 PSG11 LCLAT1 CEACAM1

8.76e-0654735MP:0010953
MousePhenoincreased abdominal fat pad weight

CEACAM5 PSG3 PSG11 CEACAM1

1.10e-0527734MP:0009286
MousePhenodecreased susceptibility to viral infection induced morbidity/mortality

CEACAM5 PSG3 PSG11 TLR2 CEACAM1

1.48e-0560735MP:0009790
MousePhenoabnormal cellular glucose uptake

CEACAM5 PSG3 PSG11 TLR2 STRA6 CEACAM1

1.49e-05102736MP:0003925
MousePhenoabnormal lipid oxidation

CEACAM5 PSG3 PSG11 LCLAT1 CEACAM1

1.60e-0561735MP:0010951
MousePhenoabnormal skeletal muscle triglyceride level

CEACAM5 PSG3 PSG11 CEACAM1

1.94e-0531734MP:0031413
MousePhenodecreased carbon dioxide production

CEACAM5 PSG3 PSG11 CEACAM1

1.94e-0531734MP:0008964
MousePhenoincreased insulin secretion

CEACAM5 PSG3 PSG11 TLR2 CEACAM1

2.03e-0564735MP:0003058
MousePhenodecreased skeletal muscle cell glucose uptake

CEACAM5 PSG3 PSG11 CEACAM1

3.17e-0535734MP:0031618
MousePhenoabnormal muscle triglyceride level

CEACAM5 PSG3 PSG11 CEACAM1

3.55e-0536734MP:0031412
MousePhenodecreased muscle cell glucose uptake

CEACAM5 PSG3 PSG11 CEACAM1

4.90e-0539734MP:0030022
MousePhenodecreased susceptibility to infection

CEACAM5 PSG3 PSG11 TLR2 C4A C4B TLR9 CEACAM1

5.30e-05255738MP:0002409
MousePhenopolyphagia

CEACAM5 PSG3 PSG11 LCLAT1 CEACAM1

5.99e-0580735MP:0001433
MousePhenodecreased susceptibility to Riboviria infection induced morbidity/mortality

CEACAM5 PSG3 PSG11 CEACAM1

7.93e-0544734MP:0031023
MousePhenoabnormal susceptibility to infection induced morbidity/mortality

CEACAM5 PSG3 PSG11 TLR2 C4A C4B TLR9 CEACAM1

9.96e-05279738MP:0009785
MousePhenoabnormal susceptibility to viral infection

CEACAM5 PSG3 PSG11 TLR2 C4A C4B TLR9 CEACAM1

9.96e-05279738MP:0020185
MousePhenoabnormal skeletal muscle cell glucose uptake

CEACAM5 PSG3 PSG11 CEACAM1

1.03e-0447734MP:0031617
MousePhenoabnormal intestine morphology

KL CEACAM5 MAN2C1 PSG3 PSG11 TLR2 LAMA5 C4A C4B FREM1 CEACAM1

1.15e-045467311MP:0000477
MousePhenodecreased cellular glucose uptake

CEACAM5 PSG3 PSG11 CEACAM1

1.65e-0453734MP:0003926
MousePhenoabnormal insulin secretion

KL CEACAM5 PSG3 PSG11 TLR2 CEACAM1

2.65e-04171736MP:0003564
MousePhenoabnormal endocrine pancreas secretion

KL CEACAM5 PSG3 PSG11 TLR2 CEACAM1

3.10e-04176736MP:0014195
MousePhenoabnormal pancreas secretion

KL CEACAM5 PSG3 PSG11 TLR2 CEACAM1

3.82e-04183736MP:0002694
MousePhenodecreased susceptibility to infection induced morbidity/mortality

CEACAM5 PSG3 PSG11 TLR2 CEACAM1

4.04e-04120735MP:0009786
MousePhenoabnormal muscle cell glucose uptake

CEACAM5 PSG3 PSG11 CEACAM1

4.09e-0467734MP:0004130
MousePhenoabnormal carbon dioxide production

CEACAM5 PSG3 PSG11 CEACAM1

4.09e-0467734MP:0008962
MousePhenoabnormal susceptibility to Riboviria infection

CEACAM5 PSG3 PSG11 C4A C4B CEACAM1

4.16e-04186736MP:0020912
MousePhenoincreased food intake

CEACAM5 PSG3 PSG11 TLR2 LCLAT1 CEACAM1

4.53e-04189736MP:0011939
MousePhenoabnormal pancreatic beta cell physiology

KL CEACAM5 PSG3 PSG11 TLR2 CEACAM1

5.49e-04196736MP:0003562
MousePhenoabnormal vascular wound healing

CEACAM5 PSG3 PSG11 CEACAM1

5.67e-0473734MP:0004883
MousePhenoabnormal endocrine pancreas physiology

KL CEACAM5 PSG3 PSG11 TLR2 CEACAM1

6.44e-04202736MP:0010147
MousePhenodecreased oxygen consumption

CEACAM5 PSG3 PSG11 CEACAM1

7.65e-0479734MP:0005290
MousePhenoabnormal glycogen homeostasis

CEACAM5 MAN2C1 PSG3 PSG11 CEACAM1

9.26e-04144735MP:0005438
MousePhenoabnormal blood vessel physiology

KL CEACAM5 PSG3 INF2 PSG11 C4A C4B CEACAM1

1.01e-03394738MP:0000249
DomainARM-type_fold

KPNA7 THADA PELP1 INF2 PIK3C2G UBR4 MEI1 HEATR5B

1.82e-04339878IPR016024
DomainAnaphylatoxin_comp_syst

C4A C4B

2.13e-045872IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

2.13e-045872IPR001840
DomainV-set

CEACAM5 PSG3 PSG11 CEACAM3 CRTAM CEACAM1

2.20e-04184876PF07686
DomainIg_V-set

CEACAM5 PSG3 PSG11 CEACAM3 CRTAM CEACAM1

3.35e-04199876IPR013106
DomainLRR

NTRK3 TLR2 CPN2 TLR9 STK11IP GP5

3.53e-04201876PS51450
DomainIg_2

CEACAM5 PSG3 PSG11 CEACAM1

3.74e-0473874PF13895
DomainLRRCT

TLR2 CPN2 GP5

4.39e-0432873PF01463
DomainANATO

C4A C4B

4.44e-047872SM00104
DomainANATO

C4A C4B

4.44e-047872PF01821
DomainANAPHYLATOXIN_2

C4A C4B

4.44e-047872PS01178
DomainANAPHYLATOXIN_1

C4A C4B

4.44e-047872PS01177
DomainAnaphylatoxin/fibulin

C4A C4B

4.44e-047872IPR000020
DomainThiol-ester_cl

C4A C4B

5.90e-048872PF10569
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

5.90e-048872IPR019565
DomainMacrogloblnA2_CS

C4A C4B

5.90e-048872IPR019742
DomainUQ_con

UBE2NL UBE2D2 UBE2D3

7.90e-0439873PF00179
DomainCys-rich_flank_reg_C

NTRK3 TLR2 CPN2 GP5

8.27e-0490874IPR000483
DomainLRRCT

NTRK3 TLR2 CPN2 GP5

8.27e-0490874SM00082
DomainL_dom-like

NTRK3 TLR2 INSRR CPN2 TLR9 STK11IP GP5

8.49e-04328877IPR032675
DomainUBIQUITIN_CONJUGAT_1

UBE2NL UBE2D2 UBE2D3

8.52e-0440873PS00183
DomainUBQ-conjugat_E2

UBE2NL UBE2D2 UBE2D3

9.16e-0441873IPR000608
DomainUBIQUITIN_CONJUGAT_2

UBE2NL UBE2D2 UBE2D3

9.16e-0441873PS50127
DomainA2M_N

C4A C4B

9.42e-0410872PF01835
DomainA2M_N

C4A C4B

9.42e-0410872IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

9.42e-0410872IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

9.42e-0410872PS00477
DomainA2M

C4A C4B

9.42e-0410872PF00207
DomainA2M_N_2

C4A C4B

9.42e-0410872IPR011625
DomainA2M_comp

C4A C4B

9.42e-0410872IPR011626
DomainA2M_N_2

C4A C4B

9.42e-0410872PF07703
DomainA2M_recep

C4A C4B

9.42e-0410872PF07677
DomainA2M_comp

C4A C4B

9.42e-0410872PF07678
DomainMacroglobln_a2

C4A C4B

9.42e-0410872IPR001599
DomainABC_transporter_CS

ABCC3 ABCA2 TAP2

9.83e-0442873IPR017871
DomainPKD_channel

PKD1L2 PKD1L3

1.15e-0311872PF08016
DomainTyr_kinase_rcpt_2_CS

NTRK3 INSRR

1.15e-0311872IPR002011
DomainPKD1_2_channel

PKD1L2 PKD1L3

1.15e-0311872IPR013122
DomainLRR_8

NTRK3 TLR2 CPN2 TLR9 GP5

1.22e-03171875PF13855
DomainRECEPTOR_TYR_KIN_II

NTRK3 INSRR

1.37e-0312872PS00239
DomainABC_tran

ABCC3 ABCA2 TAP2

1.45e-0348873PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCA2 TAP2

1.45e-0348873PS50893
DomainABC_TRANSPORTER_1

ABCC3 ABCA2 TAP2

1.54e-0349873PS00211
DomainIg-like_fold

CEACAM5 FN1 PSG3 PSG11 NTRK3 CEACAM3 CRTAM INSRR CAMTA2 CEACAM1

1.62e-037068710IPR013783
DomainABC_transporter-like

ABCC3 ABCA2 TAP2

1.63e-0350873IPR003439
DomainLeu-rich_rpt

NTRK3 TLR2 CPN2 TLR9 STK11IP GP5

1.67e-03271876IPR001611
Domain-

UBE2NL UBE2D2 UBE2D3

1.73e-03518733.10.110.10
DomainP_typ_ATPase_c

ATP10A ATP8B2

1.88e-0314872IPR032630
DomainP-type_ATPase_N

ATP10A ATP8B2

1.88e-0314872IPR032631
DomainP-type_ATPase_IV

ATP10A ATP8B2

1.88e-0314872IPR006539
DomainPhoLip_ATPase_C

ATP10A ATP8B2

1.88e-0314872PF16212
DomainPhoLip_ATPase_N

ATP10A ATP8B2

1.88e-0314872PF16209
DomainUBQ-conjugating_enzyme/RWD

UBE2NL UBE2D2 UBE2D3

1.93e-0353873IPR016135
Domainig

CEACAM5 PSG3 PSG11 NTRK3 CEACAM1

1.95e-03190875PF00047
DomainImmunoglobulin

CEACAM5 PSG3 PSG11 NTRK3 CEACAM1

1.95e-03190875IPR013151
DomainCRAL/TRIO_N_dom

MOSPD2 SEC14L5

2.17e-0315872IPR011074
DomainC345C

C4A C4B

2.79e-0317872SM00643
DomainLH2

PKD1L2 PKD1L3

3.13e-0318872SM00308
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

3.13e-0318872IPR008930
DomainNTR

C4A C4B

3.48e-0319872PF01759
DomainNetrin_module_non-TIMP

C4A C4B

3.48e-0319872IPR018933
DomainIG

CEACAM5 PSG3 PSG11 NTRK3 CEACAM3 CRTAM CEACAM1

3.50e-03421877SM00409
DomainIg_sub

CEACAM5 PSG3 PSG11 NTRK3 CEACAM3 CRTAM CEACAM1

3.50e-03421877IPR003599
DomainLRR_1

NTRK3 TLR2 CPN2 TLR9 GP5

3.59e-03219875PF00560
Domain-

CEACAM5 FN1 PSG3 PSG11 NTRK3 CEACAM3 CRTAM INSRR CEACAM1

3.70e-036638792.60.40.10
Domain-

NTRK3 TLR2 CPN2 TLR9 STK11IP GP5

3.87e-033218763.80.10.10
DomainPLAT

PKD1L2 PKD1L3

4.25e-0321872PS50095
Domain-

PKD1L2 PKD1L3

4.25e-03218722.60.60.20
DomainCRAL_TRIO

MOSPD2 SEC14L5

4.25e-0321872PF00650
DomainPLAT

PKD1L2 PKD1L3

4.25e-0321872PF01477
DomainPLAT/LH2_dom

PKD1L2 PKD1L3

4.25e-0321872IPR001024
DomainTIR

TLR2 TLR9

4.25e-0321872SM00255
DomainAAA+_ATPase

ABCC3 ABCA2 DYNC2H1 TAP2

4.60e-03144874IPR003593
DomainAAA

ABCC3 ABCA2 DYNC2H1 TAP2

4.60e-03144874SM00382
PathwayREACTOME_INNATE_IMMUNE_SYSTEM

RAF1 CEACAM5 MOSPD2 UBE2D2 UBE2D3 PSG3 PSG11 UBR4 TLR2 BIRC3 C4A C4B CPN2 TLR9 STK11IP CEACAM1

2.68e-059957116MM14661
Pubmed

Increased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1.

CEACAM5 PSG3 PSG11 CEACAM3 CEACAM1

2.72e-101588525490771
Pubmed

A mouse carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138841985902
Pubmed

CEACAM1+ myeloid cells control angiogenesis in inflammation.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388419273835
Pubmed

Mechanism of glucose intolerance in mice with dominant negative mutation of CEACAM1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388416638824
Pubmed

Decreased osteoclastogenesis and high bone mass in mice with impaired insulin clearance due to liver-specific inactivation to CEACAM1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388420044046
Pubmed

Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388432150576
Pubmed

Mouse hepatitis virus type 4 (JHM strains). induced fatal central nervous system disease. I. genetic control and murine neuron as the susceptible site of disease.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138846265583
Pubmed

Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388434440862
Pubmed

CEACAM1 is a potent regulator of B cell receptor complex-induced activation.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388412832451
Pubmed

CEACAM1 confers resistance toward oxygen-induced vessel damage in a mouse model of retinopathy of prematurity.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388425406283
Pubmed

Crystal structure of mouse coronavirus receptor-binding domain complexed with its murine receptor.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388421670291
Pubmed

Investigations on the usefulness of CEACAMs as potential imaging targets for molecular imaging purposes.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388422162753
Pubmed

A mouse analogue of the human carcinoembryonic antigen.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138842702644
Pubmed

Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138848380065
Pubmed

The receptor for mouse hepatitis virus in the resistant mouse strain SJL is functional: implications for the requirement of a second factor for viral infection.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138841279194
Pubmed

Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388425724769
Pubmed

High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388426374765
Pubmed

CEACAM1 deficiency delays important wound healing processes.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388422092845
Pubmed

Activation-induced expression of carcinoembryonic antigen-cell adhesion molecule 1 regulates mouse T lymphocyte function.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388411801635
Pubmed

Liver-specific reconstitution of CEACAM1 reverses the metabolic abnormalities caused by its global deletion in male mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388428913658
Pubmed

Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138848500759
Pubmed

Mouse susceptibility to mouse hepatitis virus infection is linked to viral receptor genotype.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138849343248
Pubmed

Ceacam1 deletion causes vascular alterations in large vessels.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388423800882
Pubmed

Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388419285068
Pubmed

Ceacam1 separates graft-versus-host-disease from graft-versus-tumor activity after experimental allogeneic bone marrow transplantation.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388421760897
Pubmed

Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138841719235
Pubmed

Mouse hepatitis virus utilizes two carcinoembryonic antigens as alternative receptors.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138841326665
Pubmed

Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388439168268
Pubmed

The expression of mouse biliary glycoprotein, a carcinoembryonic antigen-related gene, is down-regulated in malignant mouse tissues.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138848402684
Pubmed

Deletion of the carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1) gene contributes to colon tumor progression in a murine model of carcinogenesis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388416619040
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 controls IL-2-dependent regulatory T-cell induction in immune-mediated hepatitis in mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388429377208
Pubmed

Expression of MHV-A59 receptor glycoproteins in susceptible and resistant strains of mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138848209741
Pubmed

Leptin Resistance Contributes to Obesity in Mice with Null Mutation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388427002145
Pubmed

Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388421949477
Pubmed

Differential effects of prenatal stress on metabolic programming in diet-induced obese and dietary-resistant rats.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388426219866
Pubmed

Spatiotemporal expression of murine carcinoembryonic antigen (CEA) gene family members during mouse embryogenesis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138842133556
Pubmed

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388432521208
Pubmed

Targeted disruption of carcinoembryonic antigen-related cell adhesion molecule 1 promotes diet-induced hepatic steatosis and insulin resistance.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388419406938
Pubmed

Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388419621080
Pubmed

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388429967450
Pubmed

Expression of newly identified secretory CEACAM1(a) isoforms in the intestinal epithelium.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388419358828
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388416680193
Pubmed

The mouse biliary glycoprotein gene (Bgp): partial nucleotide sequence, expression, and chromosomal assignment.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138841653760
Pubmed

Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388434058224
Pubmed

Down-regulation of Bgp1(a) viral receptor by interferon-gamma is related to the antiviral state and resistance to mouse hepatitis virus 3 infection.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388410964771
Pubmed

Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388432169849
Pubmed

Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388422469976
Pubmed

CEACAM1 creates a pro-angiogenic tumor microenvironment that supports tumor vessel maturation.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388421532628
Pubmed

Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388428035001
Pubmed

Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388415316023
Pubmed

In vivo adaptation and persistence of Neisseria meningitidis within the nasopharyngeal mucosa.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388423935487
Pubmed

Ceacam1a-/- mice are completely resistant to infection by murine coronavirus mouse hepatitis virus A59.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388415331748
Pubmed

Organ tropism of murine coronavirus does not correlate with the expression levels of the membrane-anchored or secreted isoforms of the carcinoembryonic antigen-related cell adhesion molecule 1 receptor.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388422673933
Pubmed

Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388422406619
Pubmed

Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138847628460
Pubmed

Forced Hepatic Overexpression of CEACAM1 Curtails Diet-Induced Insulin Resistance.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388425972571
Pubmed

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388419008452
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388418544705
Pubmed

Expression of the mouse hepatitis virus receptor by central nervous system microglia.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388415220458
Pubmed

Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388418843289
Pubmed

Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388415207636
Pubmed

CEACAM1: a key regulator of vascular permeability.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388421081647
Pubmed

Pregnancy-specific glycoprotein (PSG) in baboon (Papio hamadryas): family size, domain structure, and prediction of a functional region in primate PSGs.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388411133662
Pubmed

Targeted disruption of the Ceacam1 (MHVR) gene leads to reduced susceptibility of mice to mouse hepatitis virus infection.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388411483763
Pubmed

Purification of the 110-kilodalton glycoprotein receptor for mouse hepatitis virus (MHV)-A59 from mouse liver and identification of a nonfunctional, homologous protein in MHV-resistant SJL/J mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138842164599
Pubmed

Liver-specific rescuing of CEACAM1 reverses endothelial and cardiovascular abnormalities in male mice with null deletion of Ceacam1 gene.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388429396368
Pubmed

The spike glycoprotein of murine coronavirus MHV-JHM mediates receptor-independent infection and spread in the central nervous systems of Ceacam1a-/- Mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388418003729
Pubmed

Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388426284027
Pubmed

CEACAM1 specifically suppresses B cell receptor signaling-mediated activation.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388433352461
Pubmed

Loss of CEACAM1 in hepatocytes causes hepatic fibrosis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388438381498
Pubmed

Murine coronavirus receptors are differentially expressed in the central nervous system and play virus strain-dependent roles in neuronal spread.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388420739537
Pubmed

mmCGM1a: a mouse carcinoembryonic antigen gene family member, generated by alternative splicing, functions as an adhesion molecule.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-08138841633107
Pubmed

The role of CEA-related cell adhesion molecule-1 (CEACAM1) in vascular homeostasis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388427695943
Pubmed

Generation of human CEACAM1 transgenic mice and binding of Neisseria Opa protein to their neutrophils.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388420404914
Pubmed

Loss of CEACAM1, a Tumor-Associated Factor, Attenuates Post-infarction Cardiac Remodeling by Inhibiting Apoptosis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388426911181
Pubmed

Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388432027621
Pubmed

Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388430664851
Pubmed

Role for hepatic CEACAM1 in regulating fatty acid metabolism along the adipocyte-hepatocyte axis.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388427777319
Pubmed

Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice.

CEACAM5 PSG3 PSG11 CEACAM1

2.69e-081388418848945
Pubmed

Alternative splicing of CEACAM1 by hypoxia-inducible factor-1α enhances tolerance to hepatic ischemia in mice and humans.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488437531413
Pubmed

Human CEACAM1-LF regulates lipid storage in HepG2 cells via fatty acid transporter CD36.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488434666041
Pubmed

Mice Lacking PECAM-1 and Ceacam1 Have Enhanced Platelet Secretion and Thrombus Growth: Novel Link with PAR4.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488434619794
Pubmed

SHP1 phosphatase-dependent T cell inhibition by CEACAM1 adhesion molecule isoforms.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488417081782
Pubmed

Loss of Ceacam1 promotes prostate cancer progression in Pten haploinsufficient male mice.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488432209360
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488411994468
Pubmed

CEACAM1 regulates insulin clearance in liver.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488411850617
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488420381490
Pubmed

CEACAM1 regulates integrin αIIbβ3-mediated functions in platelets.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488426196244
Pubmed

Biliary glycoprotein 1 expression during embryogenesis: correlation with events of epithelial differentiation, mesenchymal-epithelial interactions, absorption, and myogenesis.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-08148848896983
Pubmed

Acceleration of collateral development by carcinoembryonic antigen-related cell adhesion molecule 1 expression on CD11b/⁺Gr-1⁺ myeloid cells--brief report.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488422962327
Pubmed

The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488417623671
Pubmed

PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488426846848
Pubmed

CEACAM1, a SOX9 direct transcriptional target identified in the colon epithelium.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488418794798
Pubmed

Protein kinase Cε modulates insulin receptor localization and trafficking in mouse embryonic fibroblasts.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488423469261
Pubmed

Intestinal tumor progression is promoted by decreased apoptosis and dysregulated Wnt signaling in Ceacam1-/- mice.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488418454175
Pubmed

Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488422159884
Pubmed

NLRC5 deficiency protects against acute kidney injury in mice by mediating carcinoembryonic antigen-related cell adhesion molecule 1 signaling.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488429907459
Pubmed

Neutrophil CEACAM1 determines susceptibility to NETosis by regulating the S1PR2/S1PR3 axis in liver transplantation.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488436719377
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488423780386
Pubmed

Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene.

CEACAM5 PSG3 PSG11 CEACAM1

3.76e-081488428567513
InteractionPSG4 interactions

NLGN3 PSG3 PSG11

3.99e-068853int:PSG4
InteractionCOLQ interactions

PARP4 FN1 POLR2A TEP1

1.10e-0533854int:COLQ
Cytoband19q13.2

PSG3 PSG11 CEACAM3 CEACAM1

2.90e-0416488419q13.2
GeneFamilyAdenosine receptors|V-set domain containing

CEACAM5 PSG3 PSG11 CEACAM3 CRTAM CEACAM1

2.61e-05163656590
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CEACAM5 TLR2 CEACAM3 CRTAM TLR9 ENPEP CEACAM1 GP5

8.08e-05394658471
GeneFamilyCD molecules|V-set domain containing|Immunoglobulin like domain containing|Carcinoembryonic antigen related cell adhesion molecule family

CEACAM5 CEACAM3 CEACAM1

8.50e-0524653906
GeneFamilyUbiquitin conjugating enzymes E2

UBE2NL UBE2D2 UBE2D3

4.29e-0441653102
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PKD1L2 PKD1L3 FREM1

4.29e-04416531298
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

4.51e-0496521234
GeneFamilyCD molecules|Toll like receptors

TLR2 TLR9

5.62e-0410652948
GeneFamilyCD molecules|V-set domain containing|Pregnancy specific glycoproteins

PSG3 PSG11

6.85e-04116521315
GeneFamilyATPase phospholipid transporting

ATP10A ATP8B2

1.30e-03156521210
GeneFamilyComplement system|Sushi domain containing

C4A C4B

7.41e-0336652492
GeneFamilyGlycosyltransferase family 6|Blood group antigens

C4A C4B

7.82e-0337652454
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK3 INSRR

9.09e-0340652321
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KPNA7 THADA

1.05e-0243652409
CoexpressionOUYANG_PROSTATE_CANCER_MARKERS

CEACAM5 FN1 PSG3 PSG11 CEACAM1

1.08e-0735875MM757
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

ABCC3 MTMR11 PAXBP1 INF2 NPC1L1 SLC28A1 ENPEP ATP8B2

2.43e-06259878M40029
CoexpressionGIBBONS_GENETIC_MOUSE_MODEL_LUNG_ADENOCARCINOMA_DOWN_IN_METASTASIS

CEACAM5 PSG3 PSG11 CEACAM1

3.79e-0632874MM2
CoexpressionBOYLAN_MULTIPLE_MYELOMA_PCA3_DN

CEACAM5 PSG3 PSG11 HEATR5B CEACAM1

1.07e-0587875MM851
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_DN

MTMR11 CEACAM5 PSG3 PSG11 LAMA5 CEACAM1

1.53e-05159876MM760
CoexpressionWANG_RESPONSE_TO_BEXAROTENE_UP

CEACAM5 PSG3 PSG11 CEACAM1

1.97e-0548874MM531
CoexpressionGSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_UP

LPAR3 MAN2C1 RDH5 TEP1 PGAP6 SEC14L5

5.53e-05200876M9324
CoexpressionOHGUCHI_LIVER_HNF4A_TARGETS_DN

CEACAM5 PSG3 PSG11 RDH5 CPN2 CEACAM1

5.69e-05201876MM1294
CoexpressionBROWN_MYELOID_CELL_DEVELOPMENT_UP

CEACAM5 PSG3 PSG11 TLR2 CEACAM1 GP5

5.69e-05201876MM1006
CoexpressionHOLLERN_EMT_BREAST_TUMOR_DN

CEACAM5 PSG3 PSG11 MAP7 CEACAM1

8.86e-05135875MM965
CoexpressionTABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_MYELOID_CELL_AGEING

CEACAM5 FN1 PSG3 PSG11 BTG1 CEACAM1

9.13e-05219876MM3826
CoexpressionBYSTROEM_CORRELATED_WITH_IL5_DN

CEACAM5 PSG3 PSG11 CEACAM1

1.15e-0475874MM605
CoexpressionMCBRYAN_PUBERTAL_BREAST_3_4WK_UP

ABCC3 CEACAM5 FN1 PSG3 PSG11 CEACAM1

1.19e-04230876MM986
DrugAC1L1IPV

CEACAM5 PSG3 PSG11 CEACAM3 CEACAM1

6.59e-0743885CID000004683
DrugMas-G

KL CEACAM5 CEACAM3

1.93e-067883CID000195918
DrugKI-8110

CEACAM5 FN1 CEACAM3

9.00e-0611883CID003081597
DrugMinaprine dihydrochloride [25953-17-7]; Up 200; 10.8uM; HL60; HG-U133A

UBE2NL CEACAM5 FN1 POLR2A CEACAM3 STRA6 PGAP6

1.11e-051968871968_UP
DrugDiflorasone Diacetate [33564-31-7]; Down 200; 8uM; MCF7; HT_HG-U133A

NR2F6 ABCA2 FN1 POLR2A TLR2 IL17RC TCTN2

1.15e-051978874158_DN
DrugNicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; HL60; HG-U133A

UBE2NL NR2F6 CEACAM5 FN1 POLR2A SMG5 TCTN2

1.15e-051978871600_DN
DrugNalidixic acid sodium salt hydrate; Up 200; 14.6uM; PC3; HT_HG-U133A

NR2F6 FN1 CEACAM3 TRAPPC10 SEC14L5 CEACAM1 TCTN2

1.22e-051998877367_UP
DrugArg-Phe-Asp-Ser

FN1 ENPEP

4.42e-053882CID005236782
Drug2-aminothiophenol

C4A C4B

4.42e-053882ctd:C005464
DrugRodorubicine

CEACAM5 CEACAM3

4.42e-053882CID000057097
DrugP3cs

TLR2 TLR9 ENPEP

5.17e-0519883CID000126985
DrugAC1L2ZKY

RAF1 FN1

8.82e-054882CID000131675
DrugPromazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A

ABCC3 ABCA2 EXD3 BIRC3 ATP10A CEACAM1

9.31e-051898864308_UP
DrugAcetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; HL60; HG-U133A

UBE2NL ABCA2 CEACAM5 FN1 INF2 CEACAM3

1.07e-041948861377_DN
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

LPAR3 NTRK3 UBR4 BIRC3 ENPEP GP5

1.11e-041958866183_UP
DrugIsradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A

ABCA2 EXD3 FN1 INF2 STRA6 TEP1

1.11e-041958865447_DN
DrugEthotoin [86-35-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A

ABCC3 LPAR3 FN1 PSG11 CEACAM3 CEACAM1

1.11e-041958866052_UP
DrugClorsulon [60200-06-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A

NR2F6 ABCA2 EXD3 LMF1 STRA6 TCTN2

1.11e-041958862884_DN
DrugMeptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; HL60; HT_HG-U133A

LPAR3 ABCA2 FN1 UBR4 RDH5 CEACAM1

1.11e-041958862906_UP
DrugCyclacillin [3485-14-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

ABCA2 PSG11 NTRK3 CEACAM3 CPN2 ATP10A

1.11e-041958863800_UP
DrugAzathioprine [446-86-6]; Down 200; 14.4uM; PC3; HT_HG-U133A

NR2F6 CEACAM5 INF2 CEACAM3 IL17RC ATP8B2

1.14e-041968864667_DN
DrugMethylergometrine maleate [113-42-8]; Up 200; 8.8uM; PC3; HT_HG-U133A

EXD3 KL CEACAM5 CEACAM3 CPN2 ENPEP

1.14e-041968866704_UP
DrugKanamycin A sulfate [25389-94-0]; Up 200; 6.8uM; PC3; HT_HG-U133A

NR2F6 KL FN1 PIK3C2G PSG11 CPN2

1.17e-041978864625_UP
DrugSulfamerazine [127-79-7]; Up 200; 15.2uM; HL60; HT_HG-U133A

LMF1 UBR4 BIRC3 IL17RC MAP7 GP5

1.17e-041978862181_UP
DrugIsoxicam [34552-84-6]; Up 200; 12uM; MCF7; HT_HG-U133A

LMF1 SRD5A3 FN1 CPN2 STRA6 TCTN2

1.17e-041978861698_UP
DrugPrazosin hydrochloride [19237-84-4]; Up 200; 9.6uM; HL60; HT_HG-U133A

UBE2NL ABCA2 LMF1 SMG5 ATP10A ATP8B2

1.17e-041978863098_UP
DrugHalofantrine hydrochloride [36167-63-2]; Down 200; 7.4uM; MCF7; HT_HG-U133A

UBE2NL SRD5A3 SMG5 ATP8B2 B3GAT3 TCTN2

1.17e-041978866509_DN
DrugPhthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A

ABCA2 CDADC1 BIRC3 CPN2 STRA6 ATP10A

1.17e-041978865249_UP
DrugAllantoin [97-59-6]; Up 200; 25.2uM; HL60; HT_HG-U133A

ABCA2 FN1 INF2 IL17RC ATP8B2 TCTN2

1.17e-041978861842_UP
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

ABCA2 EXD3 DYNC2H1 POLR2A STRA6 TEP1

1.20e-041988863869_DN
DrugPhenazopyridine hydrochloride [136-40-3]; Up 200; 16uM; HL60; HT_HG-U133A

LPAR3 CEACAM5 FN1 CEACAM3 ENPEP SEC14L5

1.20e-041988862537_UP
DrugTadjakonine [11087-94-8]; Down 200; 7.4uM; HL60; HT_HG-U133A

UBE2NL BIRC3 SMG5 TEP1 ATP8B2 TCTN2

1.24e-041998862165_DN
DrugRonidazole [7681-76-7]; Up 200; 20uM; HL60; HT_HG-U133A

LPAR3 ABCA2 LMF1 IL17RC CPN2 ENPEP

1.24e-041998866134_UP
DrugPiretanide [55837-27-9]; Down 200; 11uM; PC3; HT_HG-U133A

ABCA2 EXD3 CEACAM5 FN1 SMG5 TCTN2

1.24e-041998864490_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ABCC3 MAN2C1 SRD5A3 INF2 CAMTA2 TEP1

1.24e-041998864526_DN
DrugFelbinac [5728-52-9]; Down 200; 18.8uM; HL60; HT_HG-U133A

LPAR3 ABCA2 KL FN1 DYNC2H1 CEACAM1

1.24e-041998863061_DN
DrugPromazine hydrochloride [53-60-1]; Up 200; 12.4uM; MCF7; HT_HG-U133A

ABCC3 LPAR3 UBE2NL FN1 TLR2 ATP10A

1.27e-042008863927_UP
DrugNialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A

MTMR11 CEACAM5 INF2 CDADC1 MAP7 TEP1

1.27e-042008864525_DN
Drugfluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

ABCA2 UBE2D2 INF2 DYNC2H1 LAMA5 B3GAT3

1.27e-042008866996_DN
Drugokadaic acid tetramethyl ether

RAF1 FN1

1.47e-045882CID000147507
Diseasesystemic lupus erythematosus (is_implicated_in)

C4A C4B TLR9 TAP2

3.15e-0562854DOID:9074 (is_implicated_in)
Diseasepregnanediol-3-glucuronide measurement

ABCC3 SLC22A24

2.27e-048852EFO_0800341
Diseasepulmonary tuberculosis (is_implicated_in)

TLR2 TLR9 TAP2

2.44e-0442853DOID:2957 (is_implicated_in)
Diseaseend stage renal disease (is_marker_for)

KL FN1 TLR2

3.20e-0446853DOID:783 (is_marker_for)
Diseasecutaneous leishmaniasis (is_marker_for)

TLR2 TLR9

3.64e-0410852DOID:9111 (is_marker_for)
DiseaseDisorder of eye

CACNA2D4 RDH5 STRA6 FREM1 TCTN2

3.76e-04212855C0015397
Diseasediffuse scleroderma (is_implicated_in)

TLR2 TAP2

4.44e-0411852DOID:1580 (is_implicated_in)
Diseaserenal cell carcinoma (is_marker_for)

FN1 BIRC3 PFAS TLR9

5.21e-04128854DOID:4450 (is_marker_for)
DiseaseNight blindness, congenital stationary

CACNA2D4 RDH5

1.08e-0317852C0339535
Diseaseallergic rhinitis (is_marker_for)

TLR2 TLR9

1.08e-0317852DOID:4481 (is_marker_for)
Diseaserenal fibrosis (implicated_via_orthology)

TLR2 GPR52

1.08e-0317852DOID:0050855 (implicated_via_orthology)
Diseasedermatomyositis (is_marker_for)

TLR2 TLR9

1.08e-0317852DOID:10223 (is_marker_for)
Diseaseperinatal necrotizing enterocolitis (biomarker_via_orthology)

TLR2 TLR9

1.08e-0317852DOID:8677 (biomarker_via_orthology)
Diseasesinusitis (is_marker_for)

TLR2 TLR9

1.22e-0318852DOID:0050127 (is_marker_for)
Diseasesmall cell lung carcinoma

DYNC2H1 CRTAM IL17RC

1.62e-0380853EFO_0000702
Diseasevitiligo (is_implicated_in)

TLR2 C4A

1.66e-0321852DOID:12306 (is_implicated_in)
Diseasehepatocellular carcinoma (is_implicated_in)

TLR2 BIRC3 TLR9 TEP1

1.88e-03181854DOID:684 (is_implicated_in)
Diseaseapolipoprotein L1 measurement

CPN2 PKD1L3

2.36e-0325852EFO_0021854
Diseaseacute necrotizing pancreatitis (biomarker_via_orthology)

TLR2 TLR9

2.55e-0326852DOID:0080998 (biomarker_via_orthology)
Diseaseanogenital venereal wart (is_marker_for)

TLR2 TLR9

2.55e-0326852DOID:11168 (is_marker_for)
Diseasecolorectal adenocarcinoma (is_marker_for)

RAF1 STRA6

2.75e-0327852DOID:0050861 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
WSPALQIRTVLLSIQ

UBE2NL

96

Q5JXB2
LSQTLSLVPRLHWLL

B3GAT3

96

O94766
LWLQRNAITHLPLSI

CPN2

246

P22792
RFQILTLWLPDSLTT

C4B

791

P0C0L5
QRLLLTASLLTFWNP

CEACAM5

16

P06731
ARRFLSLPSTQLDWL

CAMTA2

616

O94983
ARLLTFQTWPLTFLS

BIRC3

171

Q13489
PRLSKVNLFTLLSLW

CDADC1

31

Q9BWV3
TLLLWQARLKSNRPS

FAM200A

381

Q8TCP9
LSSLFSLPTFSLLNW

ATP10A

1426

O60312
LQLIPQISSLSWFTT

ATP8B2

86

P98198
DWSNIRQLLLFPNST

RAF1

186

P04049
LPVADQVALLRLSWS

NR2F6

226

P10588
TILRRWTFSQPLEAL

PIK3C2G

711

O75747
FLNLLWSAPLQIILA

ABCC3

426

O15438
AAVIRNLTALWNPSL

CDKN2A-DT

36

Q9UH64
LPITFLRNITWTLSN

KPNA7

211

A9QM74
FPALQTLRNRVWLLS

KIAA0100

806

Q14667
LQLSPWESSVVNRLL

MAP7

216

Q14244
TLSWQLFQTLSLREL

NTRK3

141

Q16288
VWLFSRGALTPLNQL

MTMR11

561

A4FU01
SWLLQDPRLLLRTTN

GLB1L3

176

Q8NCI6
NNRLVATWLTLPVAL

LCLAT1

81

Q6UWP7
LCFTASIAPQLLWNL

OR2W5P

71

A6NFC9
LLLAWASPTFISINR

FREM1

16

Q5H8C1
RWFLLLALLNSVVNP

LPAR3

276

Q9UBY5
WLNGTVSLPVNLRLL

ENPEP

771

Q07075
LSLSAWSRRANLIIP

PGAP6

446

Q9HCN3
IVARLNLTSPDLFWL

LAMA5

916

O15230
TTVPLLLANLLSWGQ

OR11L1

76

Q8NGX0
NQSLLASSEWPELRL

PARP4

1221

Q9UKK3
FNPLIRLQLLTWTPL

PAXBP1

626

Q9Y5B6
ILIGRLLPQVLNSWS

PELP1

396

Q8IZL8
RVLDNPTLSFLTTWL

GPR52

291

Q9Y2T5
LEPTLRSSQLLWEAL

INF2

301

Q27J81
LRGFWPRSLTLLQSN

PKD1L2

716

Q7Z442
VASQPWNRFLLFTLL

MEI1

1146

Q5TIA1
LWALLLRLAQSEPYT

NPC1L1

11

Q9UHC9
ALNPLRAVWLTLTAA

SRD5A3

11

Q9H8P0
LWFLSLALRASTQAP

NLGN3

26

Q9NZ94
LNTLQPKDTFRLWLT

DYNC2H1

3796

Q8NCM8
LLSVLHRLLLTWNPS

HEATR5B

1641

Q9P2D3
HRLLLTWNPSSVQLL

HEATR5B

1646

Q9P2D3
ITQILRNPWFSRLDS

LINC01599

116

Q8WXQ3
LSLLAWFPLQEASLT

CRTAM

6

O95727
QGLLLTASLLTFWNP

CEACAM1

16

P13688
DSSLIQQVLLRPSFW

DYTN

36

A2CJ06
RFLATTPNSLLVSWQ

FN1

2001

P02751
SPISAFLTATRWLLQ

CACNA2D4

956

Q7Z3S7
LWRFLTQNLSLPNST

ABCA2

161

Q9BZC7
QGLLLTASLLNFWNP

CEACAM3

16

P40198
AWFLLQISPNSRLSQ

MAN2C1

771

Q9NTJ4
QSWNLLDVELPLSRT

INSRR

541

P14616
WLNRTQLRTLPAAAF

GP5

296

P40197
SPNLRQLLSWIDLEF

KL

391

Q9UEF7
TALLLNFWNLPTTAQ

PSG11

21

Q9UQ72
LWTLISPFINENTRR

SEC14L5

431

O43304
TSQLLALLAWLRSPR

KIFC2

121

Q96AC6
RFQILTLWLPDSLTT

C4A

791

P0C0L4
RLQLLTLQSWLLDAP

IL17RC

376

Q8NAC3
TALLLNFWNLPTTAQ

PSG3

21

Q16557
LGLNLPWRSLSSNLV

PPEF1

516

O14829
LAAARLLSTWQRLPQ

ITPRIPL2

491

Q3MIP1
SVNDLNESSIPRWLL

MOSPD2

76

Q8NHP6
SWLQLTLAVPLQDLS

STK11IP

851

Q8N1F8
LLNFLIWQDALPSSL

THADA

851

Q6YHU6
LWALLNLTVALAFNP

PRSS58

6

Q8IYP2
SLWNRLSVLLNLLPA

SMG5

681

Q9UPR3
NTFILSLEWTLPRSR

SLC22A24

216

Q8N4F4
LLATVQLWNLLRHSP

PKD1L3

1561

Q7Z443
RFLWSLPQSDLLRGN

SIX4

131

Q9UIU6
SNWLPLNANVLLRSL

TAP2

261

Q03519
WLLRDRQSLPASNAF

RDH5

16

Q92781
RNLLLFRSLESSWPF

STRA6

461

Q9BX79
SQELFRLLPSELTLW

BTG1

91

P62324
LDILRSQWSPALTIS

UBE2D2

86

P62837
DLSLLSWLQNLPSSV

WDR47

241

O94967
SLQSLWLLSRFQKPV

TEP1

2001

Q99973
IWLDLSQNRLHTLLP

TLR9

631

Q9NR96
TLTTSPWLQLFINAR

PFAS

1316

O15067
ILPWSTFRLNLSVTT

POLR2A

476

P24928
LDILRSQWSPALTIS

UBE2D3

86

P61077
LWLSLDTSQRPEQLV

SLC28A1

166

O00337
LRSAQIWSLASPLRS

ZNF445

161

P59923
FSRQCTLLLFLQRPW

TRAPPC10

311

P48553
PQSLSVLSRLLLIWQ

UBR4

751

Q5T4S7
SLRLADVLWNSQIPL

NAE1

136

Q13564
WPSLQTLILRQNHLA

TLR2

386

O60603
LLFLTLALFLSNPWT

TCTN2

676

Q96GX1
AWLSVPVVLNLLSSR

LMF1

376

Q96S06
DPLLLLQALQTLWST

EXD3

21

Q8N9H8