Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 HOOK2 DNAH9 DNAH14 DNAH11

1.06e-0728845GO:0051959
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH9 DNAH14 DNAH11

8.52e-0718844GO:0008569
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH9 DNAH14 DNAH11

1.73e-0537844GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 DNAH9 DNAH14 DNAH11

2.16e-0470844GO:0003777
GeneOntologyCellularComponentdynein complex

DNHD1 DNAH9 DNAH14 DNAH11

6.90e-0554854GO:0030286
HumanPhenoRhinitis

BLM CLCN7 TCIRG1 DNAH9 DNAH11 SPINK5

2.64e-05113286HP:0012384
HumanPhenoChronic rhinitis

CLCN7 TCIRG1 DNAH9 DNAH11 SPINK5

4.00e-0573285HP:0002257
MousePhenoabnormal kidney size

NCOA2 AP4E1 COL6A3 STAG1 DIS3L COL27A1 WNT11 TCIRG1 LAMP1 ABCC2 ZNF236 ARHGEF17 ACE

9.75e-067146113MP:0002706
MousePhenoenlarged kidney

AP4E1 COL6A3 STAG1 DIS3L COL27A1 TCIRG1 ABCC2 ZNF236 ARHGEF17

2.10e-05354619MP:0003068
MousePhenoabnormal kidney morphology

NCOA2 AP4E1 COL6A3 CLCN7 STAG1 JADE3 DIS3L COL27A1 PDGFD WNT11 TCIRG1 LAMP1 ABCC2 ZNF236 ARHGEF17 ACE DNAH11

4.92e-0513636117MP:0002135
DomainDynein_HC_stalk

DNHD1 DNAH9 DNAH14 DNAH11

3.86e-0714854IPR024743
DomainMT

DNHD1 DNAH9 DNAH14 DNAH11

3.86e-0714854PF12777
DomainDHC_fam

DNHD1 DNAH9 DNAH14 DNAH11

5.25e-0715854IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH9 DNAH14 DNAH11

5.25e-0715854IPR004273
DomainDynein_heavy

DNHD1 DNAH9 DNAH14 DNAH11

5.25e-0715854PF03028
DomainDynein_heavy_chain_D4_dom

DNAH9 DNAH14 DNAH11

3.19e-0514853IPR024317
DomainDynein_heavy_dom-2

DNHD1 DNAH9 DNAH11

3.19e-0514853IPR013602
DomainDHC_N2

DNHD1 DNAH9 DNAH11

3.19e-0514853PF08393
DomainAAA_8

DNAH9 DNAH14 DNAH11

3.19e-0514853PF12780
DomainATPase_dyneun-rel_AAA

MDN1 DNAH9 DNAH11

3.19e-0514853IPR011704
DomainAAA_5

MDN1 DNAH9 DNAH11

3.19e-0514853PF07728
DomainDHC_N1

DNAH9 DNAH11

5.63e-048852PF08385
DomainDynein_heavy_dom-1

DNAH9 DNAH11

5.63e-048852IPR013594
DomainARM-type_fold

AP4E1 USP34 THADA STAG1 NBEAL1 MROH2A TARBP1

8.96e-04339857IPR016024
DomainDUF4599

SPATA31C2 SPATA31A6

1.31e-0312852PF15371
DomainDUF4599

SPATA31C2 SPATA31A6

1.31e-0312852IPR027970
Domain-

BLM DNHD1 TPST1 MDN1 DNM1L ABCC2 DNAH9 DNAH14 CARD14 DNAH11

2.04e-0374685103.40.50.300
DomainZZ

DRP2 KCMF1

2.99e-0318852PF00569
DomainZF_ZZ_2

DRP2 KCMF1

2.99e-0318852PS50135
DomainZF_ZZ_1

DRP2 KCMF1

2.99e-0318852PS01357
DomainZnf_ZZ

DRP2 KCMF1

3.33e-0319852IPR000433
DomainZnF_ZZ

DRP2 KCMF1

3.33e-0319852SM00291
DomainAAA+_ATPase

MDN1 ABCC2 DNAH9 DNAH11

4.23e-03144854IPR003593
DomainAAA

MDN1 ABCC2 DNAH9 DNAH11

4.23e-03144854SM00382
DomainSpectrin

DRP2 SYNE2

4.87e-0323852PF00435
DomainP-loop_NTPase

BLM DNHD1 TPST1 MDN1 DNM1L ABCC2 DNAH9 DNAH14 CARD14 DNAH11

5.08e-038488510IPR027417
DomainMetal_Hydrolase

CAD TATDN1

5.29e-0324852IPR032466
DomainSpectrin_repeat

DRP2 SYNE2

7.67e-0329852IPR002017
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

VANGL2 USP34 TRIM66 THADA EHMT2 ZNF827 DIS3L INTS13 BCAS2 ACTR6 FAT3 MCC HIC2 DDB1

5.98e-071116861431753913
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

VANGL2 BLM THADA CAD MDN1 FAF2 CLCN7 EHMT2 BCAS2 RRP9 SYNE2 GATB DDB1 CLUH RPL9

3.40e-061487861533957083
Pubmed

CLCN7 and TCIRG1 mutations differentially affect bone matrix mineralization in osteopetrotic individuals.

CLCN7 TCIRG1

6.04e-06286224108692
Pubmed

Chloride channel ClCN7 mutations are responsible for severe recessive, dominant, and intermediate osteopetrosis.

CLCN7 TCIRG1

6.04e-06286214584882
Pubmed

Novel mutations in Indian patients with autosomal recessive infantile malignant osteopetrosis.

CLCN7 TCIRG1

6.04e-06286220424301
Pubmed

CLCN7 and TCIRG1 mutations in a single family: Evidence for digenic inheritance of osteopetrosis.

CLCN7 TCIRG1

6.04e-06286230431110
Pubmed

Inhibition of the Tumor Suppressor Gene SPINK5 via EHMT2 Induces the Oral Squamous Cell Carcinoma Development.

EHMT2 SPINK5

6.04e-06286237071303
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

TRIM66 MDN1 ERC2 ARHGEF17 DNAH9

6.23e-061048659205841
Pubmed

CircHIPK3 contributes to human villous trophoblast growth, migration and invasion via modulating the pathway of miR-346/KCMF1.

HIPK3 KCMF1

1.81e-05386235032791
Pubmed

Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration.

CLCN7 TCIRG1

1.81e-05386215706348
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA2 CAD MDN1 HCN4 EHMT2 PAK5 SYNE2 MCC DNM1L ERC2 DDB1

2.55e-05963861128671696
Pubmed

NCOA2 promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA.

NCOA2 CAD FAF2 RPL9

2.82e-057086431751430
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BLM USP34 CAD MDN1 RRP9 SYNE2 DDB1 CLUH RPL9

3.49e-0565386922586326
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

3.61e-05486236140829
Pubmed

A single-center experience in 20 patients with infantile malignant osteopetrosis.

CLCN7 TCIRG1

3.61e-05486219507210
Pubmed

The use of whole exome sequencing for the diagnosis of autosomal recessive malignant infantile osteopetrosis.

CLCN7 TCIRG1

3.61e-05486227187610
Pubmed

LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.

MDN1 EHMT2 DNM1L DDB1

4.54e-057986426446488
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

6.01e-05586226909801
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

VANGL2 CAD MDN1 FAF2 BCAS2 DDB1 CLUH

6.12e-0539986737536630
Pubmed

Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3.

RSPO3 HCN4 WNT11

6.24e-053186325053429
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

VANGL2 BLM THADA CAD MDN1 FAF2 EHMT2 RRP9 SYNE2 GATB DNM1L DDB1 CLUH

7.65e-051496861332877691
Pubmed

The functional interactome landscape of the human histone deacetylase family.

CAD MDN1 STAG1 EHMT2 ZNF827 SYNE2

8.42e-0528986623752268
Pubmed

HIV-1 Vpr triggers mitochondrial destruction by impairing Mfn2-mediated ER-mitochondria interaction.

DNM1L DDB1

9.01e-05686222438978
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH9 DNAH11

9.01e-05686233347437
Pubmed

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

INTS13 HIC2 DDB1 RPL9

1.23e-0410286426584622
Pubmed

Wnt proteins contribute to neuromuscular junction formation through distinct signaling pathways.

VANGL2 WNT11

1.26e-04786228348167
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

VANGL2 FAT3

1.26e-04786222510986
Pubmed

Identifying key m6A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses.

ERC2 ZNF236

1.26e-04786236482889
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH9 DNAH11

1.26e-04786231178125
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

NCOA2 DNHD1 FAF2 COL27A1 DNM1L

1.71e-0420886533230847
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA2 MDN1 DRP2 FAF2 INTS13 SYNE2 TARBP1 DNAH11

1.85e-0463886831182584
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

BLM USP34 CAD MDN1 EHMT2 INTS13 BCAS2 DNM1L DDB1 PDXK

2.03e-041014861032416067
Pubmed

Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.

VANGL2 WNT11

2.15e-04986223095888
Pubmed

The -9247 T/C polymorphism in the SOST upstream regulatory region that potentially affects C/EBPalpha and FOXA1 binding is associated with osteoporosis.

CLCN7 TCIRG1

2.15e-04986219371798
Pubmed

Wnt-induced Vangl2 phosphorylation is dose-dependently required for planar cell polarity in mammalian development.

VANGL2 LAMP1

2.68e-041086229056748
Pubmed

Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract.

VANGL2 WNT11

2.68e-041086215637299
Pubmed

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

VANGL2 WNT11

2.68e-041086218604206
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

BLM USP34 THADA MDN1 FAF2 CLCN7 PTPRM CD38 TCIRG1 HOOK2

2.91e-041061861033845483
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 CAD MDN1 FAT3 ARHGEF17

2.95e-0423486536243803
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

THADA MDN1 NBEAL1 DNM1L CLUH TARBP1 RPL9 DNAH11

3.11e-0468986836543142
Pubmed

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex.

VANGL2 WNT11

3.28e-041186218606138
Pubmed

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal.

ACTR6 COL27A1 PDGFD

3.49e-045586319884258
Pubmed

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

HCN4 SYNE2

3.93e-041286222544366
Pubmed

Candidate positive targets of LHX6 and LHX8 transcription factors in the developing upper jaw.

RSPO3 WNT11

3.93e-041286234861428
Pubmed

A role for Saccharomyces cerevisiae Centrin (Cdc31) in mitochondrial function and biogenesis.

MDN1 DDI1

3.93e-041286230251372
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

COL6A3 MCC ACE CARD14

4.36e-0414286419851296
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

COL6A3 MCC ACE CARD14

4.48e-0414386420198315
Pubmed

The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

AP4E1 HOOK2

4.63e-041386232073997
Pubmed

A data set of human endogenous protein ubiquitination sites.

DDB1 RPL9

4.63e-041386220972266
Pubmed

Identification of novel oocyte and granulosa cell markers.

NCOA2 ZFP69

4.63e-041386219539053
Pubmed

Ambra1 deficiency impairs mitophagy in skeletal muscle.

DNM1L LAMP1

4.63e-041386235593053
Pubmed

Differential gene expression in migrating cortical interneurons during mouse forebrain development.

PTPRM ASTN1

4.63e-041386220151419
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

BLM MDN1 STAG1 INTS13 BCAS2 DNM1L DDB1

6.09e-0458286720467437
Pubmed

CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.

DNM1L LAMP1

6.21e-041586234048907
Pubmed

Id2 controls specification of Lgr5+ intestinal stem cell progenitors during gut development.

RSPO3 WNT11

6.21e-041586228077488
Pubmed

Prickle1 mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects.

VANGL2 WNT11

6.21e-041586226883626
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

VANGL2 USP34 FAF2 PTPRM MCC DNM1L HOOK2 DDB1 CLUH

6.83e-0497486928675297
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

BLM AP4E1 USP34 THADA FAF2 EHMT2 DNM1L RPL9

6.86e-0477786835844135
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

USP34 MDN1 EHMT2 KCMF1 DNM1L

6.90e-0428286523667531
Pubmed

Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2.

VANGL2 WNT11

7.09e-041686217767158
Pubmed

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.

GATB TARBP1

7.09e-041686217903297
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 THADA CAD MDN1 FAF2 RRP9 DNM1L DDB1 CLUH RPL9 PDXK

7.68e-041425861130948266
Pubmed

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.

AP4E1 DNM1L HOOK2

7.70e-047286334882091
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

BLM CAD ACTR6 RRP9 RPL9 LRCH3

7.94e-0444086634244565
Pubmed

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.

VANGL2 WNT11

8.02e-041786228292423
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 THADA CAD MDN1 FAF2 BCAS2 SYNE2 HOOK2 DDB1 PDXK LRCH3

8.37e-041440861130833792
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

TRIM66 DNAH9 DDB1

8.67e-047586325593309
Pubmed

CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1.

BCAS2 SYNE2

9.01e-041886233361760
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

BLM USP34 MDN1 STAG1 ZNF827 INTS13

9.23e-0445386629656893
Pubmed

Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.

RSPO3 WNT11

1.01e-031986228834739
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CAD MDN1 FAF2 BCAS2 DNM1L DDB1 RPL9

1.04e-0363886733239621
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIPK3 NCOA2 THADA ZNF827 INPP4A HOOK2 ZNF236 TATDN1 DNAH14 PDXK LRCH3

1.10e-031489861128611215
Pubmed

SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects.

VANGL2 WNT11

1.12e-032086232511952
Pubmed

T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.

VANGL2 WNT11

1.23e-032186217119020
Pubmed

Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.

WNT11 DNAH11

1.23e-032186216291790
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

BLM CAD BCAS2 RRP9 DDB1 RPL9

1.28e-0348386636912080
Pubmed

Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.

VANGL2 WNT11

1.35e-032286227582005
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

CAD MDN1 DDB1 RPL9

1.48e-0319786431620119
Pubmed

Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.

VANGL2 WNT11

1.48e-032386221035938
Pubmed

Genomic variants in an inbred mouse model predict mania-like behaviors.

CAD DNAH11

1.48e-032386229768498
Pubmed

GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.

DNHD1 THADA

1.48e-032386223725790
Pubmed

Primary cilia in murine palatal rugae development.

VANGL2 WNT11

1.48e-032386231226309
Pubmed

Mesenchymal Wnts are required for morphogenetic movements of calvarial osteoblasts during apical expansion.

VANGL2 WNT11

1.61e-032486238814743
Pubmed

Atmin mediates kidney morphogenesis by modulating Wnt signaling.

VANGL2 WNT11

1.61e-032486224852369
Pubmed

An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity.

VANGL2 DNM1L

1.75e-032586237589075
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

CAD EHMT2 BCAS2 SYNE2 WNT11

1.98e-0335886532460013
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

RSPO3 CLCN7 JADE3 TCIRG1

2.00e-0321486422199357
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

USP34 COL6A3 MDN1 ERC2 ZNF112

2.10e-0336386514691545
Pubmed

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes.

VANGL2 WNT11

2.19e-032886220940229
Pubmed

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

DIS3L MCC

2.19e-032886224483146
Pubmed

Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.

RSPO3 WNT11

2.35e-032986222956684
Pubmed

TopBP1 controls BLM protein level to maintain genome stability.

BLM DDB1

2.35e-032986224239288
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

USP34 SYNE2 ERC2 HIC2

2.39e-0322586412168954
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

VANGL2 MDN1 CLCN7 SYNE2 RPL9

2.42e-0337586532788342
GeneFamilyDyneins, axonemal

DNAH9 DNAH14 DNAH11

2.29e-0517603536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DRP2 KCMF1

1.60e-031860291
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE MROH2A FAT3 PAK5 ASTN1 DNAH9

6.84e-07160866c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE MROH2A FAT3 PAK5 ASTN1 DNAH9

6.84e-0716086625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

DNHD1 FBXL22 RRP9 DDB1 CLUH TARBP1

1.08e-06173866d11705e56b6b21eec963ea224717f27680c781ed
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE DRP2 MROH2A FAT3 DNAH9 DNAH11

1.55e-061848662cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE DRP2 MROH2A FAT3 DNAH9 DNAH11

1.55e-06184866ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE DRP2 MROH2A FAT3 DNAH9 DNAH11

1.55e-061848662b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE FAT3 SYNE2 DNAH14 PDXK DNAH11

1.81e-06189866904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

HIPK3 LRRC8C TCIRG1 ABCC2 CARD14

1.35e-051578652c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL6A3 FBXL22 FAT3 COL27A1 WNT11

1.35e-05157865b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL22 MROH2A ERC2 TMEM125 DDI1

1.47e-0516086541d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL22 MROH2A ERC2 TMEM125 DDI1

1.47e-05160865c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

MDN1 CD38 ARHGEF17 CARD14 OPHN1

1.52e-05161865347edb0de10850b7d16c40945751033289289c9b
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C TPST1 KCMF1 TENT5B DNAH11

1.87e-051688652e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

BLM DNHD1 ERC2 ARHGEF17 TENT5B

1.87e-051688658c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A FAT3 DNAH9 DNAH11 SPINK5

1.92e-0516986512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A3 THADA CLCN7 FAT3 WDR90

1.97e-05170865ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RSPO3 COL6A3 PDGFD ZNF112 TENT5B

2.21e-051748654da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VANGL2 PTPRM MROH2A COL27A1 RNASE12

2.33e-051768657292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VANGL2 PTPRM MROH2A COL27A1 RNASE12

2.33e-0517686588ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VANGL2 PTPRM PDGFD ACE TATDN1

2.60e-05180865baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VANGL2 PTPRM PDGFD ACE TATDN1

2.60e-051808652d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VANGL2 PTPRM PDGFD ACE TATDN1

2.60e-051808650f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRRC8C PTPRM PDGFD CD38 ACE

2.74e-05182865fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

NBEAL1 COL27A1 CD38 ASTN1 ARHGEF17

2.81e-05183865e3835db4795362b0442d5893baf2a78efcc20428
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

NBEAL1 COL27A1 CD38 ASTN1 ARHGEF17

2.81e-05183865273db6a3b00a93ca852498471187b642b5368185
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

NBEAL1 COL27A1 CD38 ASTN1 ARHGEF17

2.96e-05185865ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

NBEAL1 COL27A1 CD38 ASTN1 ARHGEF17

2.96e-05185865acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE TPST1 SYNE2 DNAH14 DNAH11

3.04e-05186865f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

NCOA2 USP34 STAG1 JADE3 NBEAL1

3.04e-0518686503db813598b67b1e08f759758a1c2023396921fa
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM PDGFD CD38 MCC

3.20e-05188865ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM PDGFD CD38 MCC

3.20e-05188865e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

COL27A1 ERC2 FHDC1 DNAH14 SPINK5

3.20e-05188865ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM PDGFD CD38 MCC

3.20e-051888650fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCellfacs-Heart-LV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM PDGFD CD38 MCC

3.28e-05189865d424d2554595b2304219f7324406b401711af7c2
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM PDGFD CD38 MCC

3.28e-05189865393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCellfacs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC8C PTPRM PDGFD CD38 MCC

3.28e-05189865bec57459ad4bab15b2532b57722549fec2e771fb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 SYNE2 RPL9 PDXK DNAH11

3.36e-05190865a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RSPO3 PTPRM INPP4A COL27A1 MCC

3.71e-05194865f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRM PDGFD CD38 MCC ACE

3.71e-05194865f159ef8541d75a4e98468947f231bb463bec922c
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JADE3 GATB WDR90 ABCC2

1.04e-04126864518a6e4919981b556ce6b451a91270dba976bc75
Diseasesphingomyelin 14:0 measurement

THADA PAK5 SYNE2

1.37e-0517823EFO_0010390
DiseaseOsteopetrosis - intermediate type

CLCN7 TCIRG1

2.28e-053822C0432261
DiseaseOsteopetrosis, Autosomal Recessive 6

CLCN7 TCIRG1

2.28e-053822C1969093
DiseaseInfantile malignant osteopetrosis

CLCN7 TCIRG1

4.56e-054822C1318518
Diseasecortical surface area measurement

VANGL2 NCOA2 RSPO3 USP34 THADA STAG1 NBEAL1 FAT3 PDGFD ERC2 HOOK2 DNAH11

3.31e-0413458212EFO_0010736
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 HOOK2

4.94e-0412822DOID:11726 (implicated_via_orthology)
DiseaseMental Retardation, Psychosocial

AP4E1 STAG1 INPP4A MCC

6.20e-04139824C0025363
DiseaseProfound Mental Retardation

AP4E1 STAG1 INPP4A MCC

6.20e-04139824C0020796
DiseaseMental deficiency

AP4E1 STAG1 INPP4A MCC

6.20e-04139824C0917816
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

RSPO3 STAG1 EHMT2

6.31e-0460823EFO_0021898
Diseasefree cholesterol in chylomicrons and extremely large VLDL measurement

RSPO3 STAG1 EHMT2

6.95e-0462823EFO_0022263
Diseaseneuroimaging measurement

VANGL2 THADA STAG1 NBEAL1 FAT3 PDGFD PAK5 RNASE12 ERC2 DNAH11

7.52e-0410698210EFO_0004346
Diseaseobstructive sleep apnea

TYW3 THADA ERC2

8.34e-0466823EFO_0003918
DiseaseParoxysmal atrial fibrillation

USP34 HCN4 SYNE2 ACE

9.54e-04156824C0235480
Diseasefamilial atrial fibrillation

USP34 HCN4 SYNE2 ACE

9.54e-04156824C3468561
DiseasePersistent atrial fibrillation

USP34 HCN4 SYNE2 ACE

9.54e-04156824C2585653
Diseasepsoriasis

PAK5 SYNE2 SPATA31C2 ERC2 CARD14

9.98e-04273825EFO_0000676
Diseaseglomerulonephritis (implicated_via_orthology)

PDGFD ACE

1.01e-0317822DOID:2921 (implicated_via_orthology)
DiseaseAtrial Fibrillation

USP34 HCN4 SYNE2 ACE

1.05e-03160824C0004238
Diseasevisual cortical surface area measurement

RSPO3 PDGFD

1.40e-0320822EFO_0004771
Diseaseend stage renal disease (implicated_via_orthology)

ABCC2 ACE

1.40e-0320822DOID:783 (implicated_via_orthology)
DiseaseHodgkins lymphoma

PDGFD ERC2 ACE

1.56e-0382823EFO_0000183
Diseasenon-alcoholic fatty liver disease

RSPO3 STAG1 ZNF827 TARBP1

1.68e-03182824EFO_0003095
Diseasecoronary artery disease

AP4E1 COL6A3 THADA STAG1 HCN4 ZNF827 NBEAL1 RNASE12 PDXK OPHN1

1.72e-0311948210EFO_0001645
Diseasethalamus volume

RSPO3 FAT3 ERC2

1.73e-0385823EFO_0006935
Diseaseprostate specific antigen measurement

THADA ZNF827 ST6GAL1 DNAH11

1.90e-03188824EFO_0004624
DiseaseCoronary heart disease

ACE DNAH11

2.02e-0324822C0010068
DiseaseAlbuminuria

CD38 ACE

2.02e-0324822C0001925
DiseaseFEV/FEC ratio

RSPO3 USP34 COL6A3 THADA FBXL22 PTPRM SYNE2 MCC ERC2 ARHGEF17

2.12e-0312288210EFO_0004713
DiseaseIGF-1 measurement

RSPO3 TRIM66 STAG1 SYNE2 ASTN1 TENT5B

2.41e-03488826EFO_0004627
Diseaseapolipoprotein B measurement

RSPO3 THADA STAG1 PDGFD SYNE2 ZNF112 DNAH11

2.48e-03663827EFO_0004615
Diseasetriglycerides:total lipids ratio, high density lipoprotein cholesterol measurement

RSPO3 STAG1 SYNE2 RNASE12

2.64e-03206824EFO_0004612, EFO_0020947
Diseaseprimary biliary cholangitis (biomarker_via_orthology)

ABCC2 ACE

2.75e-0328822DOID:12236 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
TMESILQHLEFCITH

VANGL2

416

Q9ULK5
QHAMECHHRIEERSQ

TPST1

26

O60507
LLDVTMVIVHEICHQ

TRHDE

431

Q9UKU6
RQLHVMDETHVINQV

ACTR6

191

Q9GZN1
CVELVHEEMQRIIQH

DNM1L

431

O00429
QCTRVTMDQLSTVHH

ACE

376

P12821
HLVLFEDAMQHVCRI

DNAH11

2826

Q96DT5
LEQLCHSVMEAHPQV

GATB

501

O75879
TMNIDRNITHLQHCT

EHMT2

961

Q96KQ7
ILRLVHEDTYHMQQC

DNHD1

461

Q96M86
EMVLQRFHQQVCSHL

DNHD1

2996

Q96M86
ITDLRHHLQRECMNG

ASTN1

246

O14525
ALQHQMTIIECLDHP

AP4E1

371

Q9UPM8
TEIHPEMRHVDCQSV

CD38

71

P28907
HIIRHMDIVTCLATD

NBEAL1

2436

Q6ZS30
HLVNVCEHSKENLMT

OPHN1

506

O60890
VTLEQCLILQHEHGM

INPP4A

906

Q96PE3
HVRMLEDCVQETIHE

INTS13

171

Q9NVM9
LEHHEQFLEQVRHCM

ARHGEF17

1121

Q96PE2
THTRMNEEQIATVCL

PAK5

536

Q9P286
QIIHMERLLIEDHCS

DDI1

46

Q8WTU0
MSCEELHSILHLVLQ

FHDC1

286

Q9C0D6
HLRHLMELDVSCNEI

LRCH3

171

Q96II8
INHDLHERLCVSMSK

MDN1

86

Q9NU22
HHICIEVDNINAAVM

MCEE

121

Q96PE7
MLCHENLIRQTNTHI

SPINK5

1026

Q9NQ38
HIQRIMTLEESVQHV

HOOK2

131

Q96ED9
IQSIHVSQDERECTM

CLCN7

721

P51798
TMALVDIQLDHHERC

PDGFD

346

Q9GZP0
CTVITIAHRLHTIMD

ABCC2

1486

Q92887
MRVSHEENQHLQLTI

ERC2

211

O15083
QHRNHTCLVFEMLEQ

HIPK3

266

Q9H422
IIQQIVQHDREMAHC

HCN4

741

Q9Y3Q4
NHCTLEQQRVMARHL

PLCD1

391

P51178
AQCEQSHLMREHEDV

MCC

56

P23508
ISLQQQLIHVMEHIC

BLM

366

P54132
QVHCNEVLHVTDTMF

CARD14

696

Q9BXL6
EVHETVAECMILANH

DIS3L

676

Q8TF46
MINLHRLCIIHVVAT

LINC00305

1

Q7Z4B0
QVLETLHDAMHETLC

COL6A3

1811

P12111
ILTARMLDHELVQHC

FAT3

2346

Q8TDW7
SSEVTQHITIHCLNM

COL27A1

1756

Q8IZC6
HMHSVNVEEITQIVL

DNAH14

906

Q0VDD8
HTTDHPMQCILTRVD

KCMF1

46

Q9P0J7
VHMNNVTVTLHDATI

LAMP1

161

P11279
EDAMRHVCHINRILE

DNAH9

2801

Q9NYC9
CNHMIIQRVIREPDH

RNASE12

46

Q5GAN4
QACDMVHHFTTEVIQ

CYP4F22

266

Q6NT55
LRQISHTEMEHEVAC

DDB1

526

Q16531
NLMEKTVEVLERHCH

JADE3

166

Q92613
TVEVLERHCHENMNH

JADE3

171

Q92613
QASEHVMDVVEVIHC

DRP2

436

Q13474
REQLDMHSIIVSCVN

FEZ2

141

Q9UHY8
AISIVCEMLRHQRTV

PTPRM

1401

P28827
MQLHTIFTELHVQVC

MROH2A

341

A6NES4
CDVIIMVENSIFRAH

HIC2

46

Q96JB3
CHIIQILEIMSAVRD

TATDN1

261

Q6P1N9
ISHHMQTCVENRELI

THADA

1661

Q6YHU6
EMLCHLQRMVSEQCH

THADA

1866

Q6YHU6
QILEENMSLCHARHA

SPATA31C2

1061

B4DYI2
QLNHHMEVLRELCEE

SYNE2

991

Q8WXH0
CTERTHIENILKAHM

SPATA31A6

716

Q5VVP1
IESMDQCRHTLEQHN

FAF2

26

Q96CS3
TMHITQLNRECLLHL

FBXL22

6

Q6P050
RCHLRDHVNVSMVEV

ST6GAL1

141

P15907
HQAVRIENLELMSQH

BCAS2

116

O75934
MEEECRVLSIQSHVI

PDXK

1

O00764
LHRVVNESTVCLMNH

TENT5B

346

Q96A09
QEIHQVLMDREDTCH

CLUH

71

O75153
LVISLHMLHREQNVC

NCOA2

366

Q15596
HILEIDCQRMVVRHA

WDR90

581

Q96KV7
ELATVRTICSHVQNM

RPL9

66

P32969
SIDCIHLINEEHMVS

RRP9

326

O43818
NNHTMECVSIVHCEV

RSPO3

136

Q9BXY4
IELMVCTIRQAAEAH

STAG1

526

Q8WVM7
MVAQLTQRSVHICHV

CAD

1601

P27708
RHLQIHLITRMFECD

ZNF827

1036

Q17R98
CSSNLDIQHRVHMEE

ZNF112

426

Q9UJU3
VQLCRSNLELMHTVV

WNT11

56

O96014
QNTCLTQHMRIHTGE

ZNF502

446

Q8TBZ5
TLQSQLAVHMEEHRQ

ZNF236

131

Q9UL36
LRDVIHCTMITHQIL

TARBP1

511

Q13395
FSHMQQHDILDTLCR

USP34

3511

Q70CQ2
HRCRHVEEVLQNQRM

TRIM66

96

O15016
VQDMNCIRQAHHVAL

TMEM125

91

Q96AQ2
EVLMHQAIHTIEFCL

TCIRG1

711

Q13488
CLQHALERETMTNLH

TYW3

191

Q6IPR3
HQETCMRDVRQAILT

ZFP69

201

Q49AA0
VDVSSHLQKMCIHND

LRRC8C

561

Q8TDW0