Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A1 ZP1 COL4A3 FBN1 FN1 MATN3 LAMA2 LTBP2 TECTA COLQ	5.91e-11	188	53	10	GO:0005201
GeneOntologyMolecularFunction	calcium ion binding	MASP1 SCUBE1 FBN1 DLL4 CCBE1 ADGRE3 MATN3 C1R LTBP2 DLL1 NOTCH2	3.47e-06	749	53	11	GO:0005509
GeneOntologyMolecularFunction	structural molecule activity	COL4A1 ZP1 COL4A3 FBN1 FN1 MATN3 LAMA2 KRTAP24-1 LTBP2 TECTA COLQ	1.79e-05	891	53	11	GO:0005198
GeneOntologyMolecularFunction	heparin binding	FBN1 FN1 RSPO2 LTBP2 COLQ	1.54e-04	192	53	5	GO:0008201
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A1 COL4A3 COLQ	2.47e-04	46	53	3	GO:0030020
GeneOntologyMolecularFunction	glycosaminoglycan binding	FBN1 FN1 RSPO2 LTBP2 COLQ	7.12e-04	268	53	5	GO:0005539
GeneOntologyMolecularFunction	sulfur compound binding	FBN1 FN1 RSPO2 LTBP2 COLQ	1.63e-03	323	53	5	GO:1901681
GeneOntologyMolecularFunction	Notch binding	DLL4 DLL1	2.33e-03	27	53	2	GO:0005112
GeneOntologyBiologicalProcess	extracellular matrix organization	COL4A1 COL4A3 FN1 MATN3 LAMA2 COLQ AXIN2	5.45e-05	377	54	7	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	COL4A1 COL4A3 FN1 MATN3 LAMA2 COLQ AXIN2	5.54e-05	378	54	7	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	COL4A1 COL4A3 FN1 MATN3 LAMA2 COLQ AXIN2	5.64e-05	379	54	7	GO:0045229
GeneOntologyBiologicalProcess	regulation of fat cell differentiation	FBN1 HDAC6 KLF5 ZFP36 AXIN2	7.74e-05	168	54	5	GO:0045598
GeneOntologyBiologicalProcess	response to growth factor	FBN1 HDAC6 BMP10 DLL4 CCBE1 CHRDL1 LTBP2 DLL1 ZFP36 NOTCH2	8.48e-05	883	54	10	GO:0070848
GeneOntologyBiologicalProcess	cardiac atrium morphogenesis	BMP10 DLL4 NOTCH2	1.05e-04	35	54	3	GO:0003209
GeneOntologyBiologicalProcess	developmental growth	LIMK1 HDAC6 FN1 BMP10 KLF5 RSPO2 DLL1 COLQ NOTCH2 ZFY	1.10e-04	911	54	10	GO:0048589
GeneOntologyBiologicalProcess	cardiac atrium development	BMP10 DLL4 NOTCH2	1.81e-04	42	54	3	GO:0003230
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	COL4A1 COL4A3 FBN1 BMP10 CCBE1 ADGRE3 CSNK2B CHRDL1 LTBP2 DLL1 NOTCH2	2.11e-04	1186	54	11	GO:0007167
GeneOntologyBiologicalProcess	axis specification	CHRDL1 DLL1 NOTCH2 AXIN2	2.19e-04	113	54	4	GO:0009798
GeneOntologyBiologicalProcess	circulatory system development	COL4A1 COL4A3 SCUBE1 FBN1 FN1 BMP10 DLL4 CCBE1 KLF5 DLL1 NOTCH2 AXIN2	2.85e-04	1442	54	12	GO:0072359
GeneOntologyBiologicalProcess	marginal zone B cell differentiation	DLL1 NOTCH2	2.99e-04	10	54	2	GO:0002315
GeneOntologyBiologicalProcess	proximal tubule development	DLL1 NOTCH2	2.99e-04	10	54	2	GO:0072014
GeneOntologyBiologicalProcess	cholangiocyte proliferation	HDAC6 NOTCH2	2.99e-04	10	54	2	GO:1990705
GeneOntologyBiologicalProcess	cell fate determination	CHRDL1 DLL1 NOTCH2	3.05e-04	50	54	3	GO:0001709
GeneOntologyBiologicalProcess	semi-lunar valve development	DLL4 NOTCH2 AXIN2	3.05e-04	50	54	3	GO:1905314
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	FBN1 BMP10 DLL4 CCBE1 CHRDL1 LTBP2 DLL1 ZFP36 NOTCH2	3.30e-04	850	54	9	GO:0071363
GeneOntologyBiologicalProcess	collagen-activated tyrosine kinase receptor signaling pathway	COL4A1 COL4A3	4.37e-04	12	54	2	GO:0038063
GeneOntologyBiologicalProcess	angiogenesis	COL4A1 COL4A3 FN1 DLL4 CCBE1 KLF5 DLL1 NOTCH2	4.77e-04	708	54	8	GO:0001525
GeneOntologyBiologicalProcess	renal system development	COL4A1 COL4A3 FBN1 BMP10 DLL1 NOTCH2	5.00e-04	386	54	6	GO:0072001
GeneOntologyBiologicalProcess	regulation of osteoclast development	FBN1 NOTCH2	5.15e-04	13	54	2	GO:2001204
GeneOntologyBiologicalProcess	tube morphogenesis	COL4A1 COL4A3 FN1 DLL4 CCBE1 KLF5 CSNK2B RSPO2 DLL1 NOTCH2	5.97e-04	1125	54	10	GO:0035239
GeneOntologyBiologicalProcess	left/right axis specification	DLL1 NOTCH2	6.00e-04	14	54	2	GO:0070986
GeneOntologyBiologicalProcess	heart valve morphogenesis	DLL4 NOTCH2 AXIN2	6.03e-04	63	54	3	GO:0003179
GeneOntologyCellularComponent	extracellular matrix	COL4A1 ZP1 COL4A3 FBN1 FCGBP FN1 OTOGL CCBE1 MATN3 LAMA2 C1QA LTBP2 TECTA COLQ	7.97e-10	656	54	14	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A1 ZP1 COL4A3 FBN1 FCGBP FN1 OTOGL CCBE1 MATN3 LAMA2 C1QA LTBP2 TECTA COLQ	8.29e-10	658	54	14	GO:0030312
GeneOntologyCellularComponent	basement membrane	COL4A1 COL4A3 FBN1 FN1 LAMA2 COLQ	7.17e-07	122	54	6	GO:0005604
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL4A1 ZP1 COL4A3 FBN1 FN1 MATN3 LAMA2 C1QA LTBP2 COLQ	8.86e-07	530	54	10	GO:0062023
GeneOntologyCellularComponent	collagen trimer	COL4A1 COL4A3 CCBE1 C1QA COLQ	3.17e-06	88	54	5	GO:0005581
GeneOntologyCellularComponent	collagen type IV trimer	COL4A1 COL4A3	9.76e-05	6	54	2	GO:0005587
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A1 COL4A3	1.82e-04	8	54	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A1 COL4A3	1.82e-04	8	54	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A1 COL4A3	1.82e-04	8	54	2	GO:0098645
GeneOntologyCellularComponent	endoplasmic reticulum lumen	COL4A1 COL4A3 FBN1 FN1 MATN3 CHRDL1	2.09e-04	332	54	6	GO:0005788
GeneOntologyCellularComponent	complex of collagen trimers	COL4A1 COL4A3	1.33e-03	21	54	2	GO:0098644
HumanPheno	Iridodonesis	FBN1 CHRDL1 LTBP2	1.65e-06	5	29	3	HP:0100693
HumanPheno	Deep anterior chamber	CHRDL1 LTBP2	3.13e-05	2	29	2	HP:0007765
HumanPheno	Abnormal vascular morphology	COL4A1 LIMK1 MASP1 FBN1 POLR1A FN1 DLL4 CCBE1 LAMA2 RSPO2 C1R LTBP2 UQCRFS1 DLL1 COLQ SH2D1A CD96 NOTCH2	4.13e-05	1319	29	18	HP:0025015
HumanPheno	Abnormal blood vessel morphology	COL4A1 LIMK1 MASP1 FBN1 POLR1A DLL4 CCBE1 LAMA2 RSPO2 C1R LTBP2 UQCRFS1 DLL1 COLQ SH2D1A CD96 NOTCH2	5.24e-05	1201	29	17	HP:0033353
HumanPheno	Ventricular septal defect	LIMK1 MASP1 FBN1 POLR1A DLL4 CCBE1 RSPO2 LTBP2 UQCRFS1 CD96 NOTCH2	5.87e-05	510	29	11	HP:0001629
HumanPheno	Abnormal ventricular septum morphology	LIMK1 MASP1 FBN1 POLR1A DLL4 CCBE1 RSPO2 LTBP2 UQCRFS1 CD96 NOTCH2	7.16e-05	521	29	11	HP:0010438
HumanPheno	Limitation of joint mobility	LIMK1 MASP1 FBN1 FN1 MATN3 LAMA2 RSPO2 LTBP2 COLQ CD96	7.95e-05	432	29	10	HP:0001376
HumanPheno	Aplasia/hypoplasia involving bones of the hand	MASP1 FBN1 HDAC6 FN1 DLL4 CCBE1 MATN3 RSPO2 LTBP2 CD96 NOTCH2	9.63e-05	538	29	11	HP:0005927
HumanPheno	Abnormality of lens shape	COL4A3 FBN1 LTBP2	1.28e-04	18	29	3	HP:0011526
HumanPheno	Abnormal cardiac ventricle morphology	LIMK1 MASP1 FBN1 POLR1A DLL4 CCBE1 LAMA2 RSPO2 LTBP2 UQCRFS1 COLQ CD96 NOTCH2	1.44e-04	780	29	13	HP:0001713
HumanPheno	Aplasia/hypoplasia involving bones of the upper limbs	MASP1 FBN1 HDAC6 FN1 DLL4 CCBE1 MATN3 RSPO2 LTBP2 CD96 NOTCH2	1.69e-04	572	29	11	HP:0006496
HumanPheno	Hyperlordosis	LIMK1 MASP1 FBN1 FN1 MATN3 LAMA2 COLQ	1.86e-04	222	29	7	HP:0003307
HumanPheno	Lordosis	LIMK1 MASP1 FBN1 FN1 MATN3 LAMA2 COLQ	1.86e-04	222	29	7	HP:0002939
HumanPheno	Microspherophakia	FBN1 LTBP2	1.86e-04	4	29	2	HP:0030961
HumanPheno	Abnormal thorax morphology	LIMK1 MASP1 VRK1 FBN1 HDAC6 POLR1A FN1 CCBE1 MATN3 LAMA2 RSPO2 C1R LTBP2 DLL1 COLQ CD96 NOTCH2	2.03e-04	1328	29	17	HP:0000765
HumanPheno	Megalocornea	LIMK1 FBN1 CHRDL1 LTBP2	2.20e-04	54	29	4	HP:0000485
HumanPheno	Anterior chamber mesodermal anomalies	LIMK1 FBN1 CHRDL1 LTBP2	2.20e-04	54	29	4	HP:0008040
HumanPheno	Spherophakia	FBN1 LTBP2	3.10e-04	5	29	2	HP:0034375
MousePheno	abnormal capillary morphology	COL4A1 COL4A3 DLL4 DLL1 NOTCH2	9.22e-06	93	43	5	MP:0003658
MousePheno	abnormal artery morphology	FBN1 FN1 BMP10 DLL4 KLF5 CAPZA2 UNK DLL1	4.98e-05	440	43	8	MP:0002191
Domain	EGF-like_dom	MASP1 SCUBE1 FBN1 FCGBP DLL4 CCBE1 ADGRE3 MATN3 LAMA2 C1R LTBP2 TECTA DLL1 NOTCH2	5.88e-15	249	53	14	IPR000742
Domain	EGF_CA	MASP1 SCUBE1 FBN1 DLL4 CCBE1 ADGRE3 MATN3 C1R LTBP2 DLL1 NOTCH2	3.53e-14	122	53	11	SM00179
Domain	EGF-like_Ca-bd_dom	MASP1 SCUBE1 FBN1 DLL4 CCBE1 ADGRE3 MATN3 C1R LTBP2 DLL1 NOTCH2	4.23e-14	124	53	11	IPR001881
Domain	EGF	SCUBE1 FBN1 FCGBP DLL4 CCBE1 ADGRE3 MATN3 LAMA2 C1R LTBP2 TECTA DLL1 NOTCH2	7.66e-14	235	53	13	SM00181
Domain	ASX_HYDROXYL	MASP1 SCUBE1 FBN1 DLL4 CCBE1 ADGRE3 C1R LTBP2 DLL1 NOTCH2	1.97e-13	100	53	10	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	MASP1 SCUBE1 FBN1 DLL4 CCBE1 ADGRE3 C1R LTBP2 DLL1 NOTCH2	3.58e-13	106	53	10	IPR000152
Domain	EGF_CA	MASP1 SCUBE1 FBN1 CCBE1 ADGRE3 MATN3 C1R LTBP2 NOTCH2	2.27e-12	86	53	9	PF07645
Domain	EGF_Ca-bd_CS	MASP1 SCUBE1 FBN1 CCBE1 ADGRE3 C1R LTBP2 DLL1 NOTCH2	6.91e-12	97	53	9	IPR018097
Domain	EGF-like_CS	MASP1 SCUBE1 FBN1 FN1 DLL4 CCBE1 MATN3 LAMA2 C1R LTBP2 DLL1 NOTCH2	6.91e-12	261	53	12	IPR013032
Domain	EGF_CA	MASP1 SCUBE1 FBN1 CCBE1 ADGRE3 C1R LTBP2 DLL1 NOTCH2	8.33e-12	99	53	9	PS01187
Domain	EGF_3	MASP1 SCUBE1 FBN1 DLL4 CCBE1 ADGRE3 MATN3 C1R LTBP2 DLL1 NOTCH2	4.74e-11	235	53	11	PS50026
Domain	EGF_1	MASP1 SCUBE1 FBN1 FN1 DLL4 CCBE1 LAMA2 C1R LTBP2 DLL1 NOTCH2	1.14e-10	255	53	11	PS00022
Domain	EGF_2	MASP1 SCUBE1 FBN1 DLL4 CCBE1 MATN3 LAMA2 C1R LTBP2 DLL1 NOTCH2	1.72e-10	265	53	11	PS01186
Domain	Growth_fac_rcpt_	SCUBE1 FBN1 DLL4 ADGRE3 MATN3 RSPO2 LTBP2 DLL1 NOTCH2	5.08e-10	156	53	9	IPR009030
Domain	EGF	DLL4 MATN3 LTBP2 TECTA DLL1 NOTCH2	1.48e-06	126	53	6	PF00008
Domain	Collagen	COL4A1 COL4A3 CCBE1 C1QA COLQ	4.19e-06	85	53	5	IPR008160
Domain	Collagen	COL4A1 COL4A3 CCBE1 C1QA COLQ	4.19e-06	85	53	5	PF01391
Domain	CUB	MASP1 SCUBE1 C1R SEZ6L2	1.11e-05	49	53	4	PF00431
Domain	CUB	MASP1 SCUBE1 C1R SEZ6L2	1.21e-05	50	53	4	SM00042
Domain	-	MASP1 SCUBE1 C1R SEZ6L2	1.41e-05	52	53	4	2.60.120.290
Domain	CUB	MASP1 SCUBE1 C1R SEZ6L2	1.53e-05	53	53	4	PS01180
Domain	CUB_dom	MASP1 SCUBE1 C1R SEZ6L2	2.04e-05	57	53	4	IPR000859
Domain	TILa	FCGBP TECTA	2.37e-05	3	53	2	PF12714
Domain	TILa_dom	FCGBP TECTA	2.37e-05	3	53	2	IPR025615
Domain	DSL	DLL4 DLL1	4.72e-05	4	53	2	PF01414
Domain	Pept_S1A_C1r/C1S/mannan-bd	MASP1 C1R	4.72e-05	4	53	2	IPR024175
Domain	DSL	DLL4 DLL1	4.72e-05	4	53	2	SM00051
Domain	DSL	DLL4 DLL1	7.86e-05	5	53	2	IPR001774
Domain	DSL	DLL4 DLL1	7.86e-05	5	53	2	PS51051
Domain	Notch_ligand_N	DLL4 DLL1	7.86e-05	5	53	2	IPR011651
Domain	MNNL	DLL4 DLL1	7.86e-05	5	53	2	PF07657
Domain	C4	COL4A1 COL4A3	1.18e-04	6	53	2	SM00111
Domain	-	COL4A1 COL4A3	1.18e-04	6	53	2	2.170.240.10
Domain	Collagen_VI_NC	COL4A1 COL4A3	1.18e-04	6	53	2	IPR001442
Domain	C4	COL4A1 COL4A3	1.18e-04	6	53	2	PF01413
Domain	NC1_IV	COL4A1 COL4A3	1.18e-04	6	53	2	PS51403
Domain	TB	FBN1 LTBP2	1.64e-04	7	53	2	PF00683
Domain	VWC	FCGBP CHRDL1 TECTA	1.70e-04	38	53	3	SM00214
Domain	-	FBN1 LTBP2	2.19e-04	8	53	2	3.90.290.10
Domain	VWF_dom	FCGBP CHRDL1 TECTA	2.29e-04	42	53	3	IPR001007
Domain	TB	FBN1 LTBP2	2.81e-04	9	53	2	PS51364
Domain	TB_dom	FBN1 LTBP2	2.81e-04	9	53	2	IPR017878
Domain	ZP_dom_CS	ZP1 TECTA	3.50e-04	10	53	2	IPR017977
Domain	Sushi	MASP1 C1R SEZ6L2	4.32e-04	52	53	3	PF00084
Domain	CCP	MASP1 C1R SEZ6L2	4.83e-04	54	53	3	SM00032
Domain	TIL	FCGBP TECTA	5.12e-04	12	53	2	PF01826
Domain	C8	FCGBP TECTA	5.12e-04	12	53	2	PF08742
Domain	SUSHI	MASP1 C1R SEZ6L2	5.38e-04	56	53	3	PS50923
Domain	Sushi_SCR_CCP_dom	MASP1 C1R SEZ6L2	5.67e-04	57	53	3	IPR000436
Domain	Unchr_dom_Cys-rich	FCGBP TECTA	6.04e-04	13	53	2	IPR014853
Domain	C8	FCGBP TECTA	6.04e-04	13	53	2	SM00832
Domain	ZP_1	ZP1 TECTA	7.03e-04	14	53	2	PS00682
Domain	TIL_dom	FCGBP TECTA	7.03e-04	14	53	2	IPR002919
Domain	ZP_2	ZP1 TECTA	7.03e-04	14	53	2	PS51034
Domain	ZP	ZP1 TECTA	8.10e-04	15	53	2	SM00241
Domain	VWD	FCGBP TECTA	9.24e-04	16	53	2	SM00216
Domain	VWF_type-D	FCGBP TECTA	9.24e-04	16	53	2	IPR001846
Domain	VWFD	FCGBP TECTA	9.24e-04	16	53	2	PS51233
Domain	VWD	FCGBP TECTA	9.24e-04	16	53	2	PF00094
Domain	ZP_dom	ZP1 TECTA	1.05e-03	17	53	2	IPR001507
Domain	Zona_pellucida	ZP1 TECTA	1.05e-03	17	53	2	PF00100
Domain	VWC_out	FCGBP TECTA	1.31e-03	19	53	2	SM00215
Domain	RHOD	MOCS3 CDC25B	1.76e-03	22	53	2	SM00450
Domain	RHODANESE_3	MOCS3 CDC25B	1.92e-03	23	53	2	PS50206
Domain	Rhodanese-like_dom	MOCS3 CDC25B	2.10e-03	24	53	2	IPR001763
Domain	Rhodanese	MOCS3 CDC25B	2.10e-03	24	53	2	PF00581
Domain	-	MOCS3 CDC25B	2.10e-03	24	53	2	3.40.250.10
Domain	cEGF	SCUBE1 FBN1	2.46e-03	26	53	2	IPR026823
Domain	cEGF	SCUBE1 FBN1	2.46e-03	26	53	2	PF12662
Domain	hEGF	DLL1 NOTCH2	2.85e-03	28	53	2	PF12661
Domain	VWFC_2	CHRDL1 TECTA	5.20e-03	38	53	2	PS50184
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A1 COL4A3 SCUBE1 FBN1 FN1 BMP10 MATN3 LAMA2 LTBP2	3.59e-07	300	45	9	M610
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL4A1 COL4A3 SCUBE1 FBN1 FN1 BMP10 MATN3 LTBP2	1.36e-06	258	45	8	MM14572
Pathway	PID_INTEGRIN1_PATHWAY	COL4A1 COL4A3 FBN1 FN1 LAMA2	2.04e-06	66	45	5	M18
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FN1 BMP10 LTBP2	3.05e-06	32	45	4	MM14854
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL4A1 COL4A3 FN1 MATN3 LAMA2	4.12e-06	76	45	5	M27219
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	FBN1 FN1 BMP10 LTBP2	5.54e-06	37	45	4	M27134
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 FN1 BMP10 LTBP2	6.87e-06	39	45	4	MM14601
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY	DLL4 DLL1 NOTCH2	8.50e-06	13	45	3	M47423
Pathway	PID_INTEGRIN3_PATHWAY	COL4A1 COL4A3 FBN1 FN1	1.02e-05	43	45	4	M53
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	FBN1 FN1 BMP10 LTBP2	1.12e-05	44	45	4	M26969
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	COL4A1 COL4A3 FN1 DLL4 DLL1 NOTCH2	1.14e-05	161	45	6	M39770
Pathway	WP_NEURAL_CREST_DIFFERENTIATION	HDAC6 DLL4 DLL1 NOTCH2 AXIN2	1.37e-05	97	45	5	MM15926
Pathway	WP_NEURAL_CREST_DIFFERENTIATION	HDAC6 DLL4 DLL1 NOTCH2 AXIN2	1.66e-05	101	45	5	M39448
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	MASP1 C1QA C1R	2.00e-05	17	45	3	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	MASP1 C1QA C1R	2.00e-05	17	45	3	MM1369
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A1 COL4A3 SCUBE1 FBN1 FN1	2.99e-05	114	45	5	MM14571
Pathway	BIOCARTA_COMP_PATHWAY	MASP1 C1QA C1R	3.34e-05	20	45	3	M917
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A1 COL4A3 FN1 LAMA2	3.63e-05	59	45	4	M27218
Pathway	REACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL4 DLL1 NOTCH2	4.49e-05	22	45	3	M27210
Pathway	WP_COMPLEMENT_ACTIVATION	MASP1 C1QA C1R	4.49e-05	22	45	3	M39502
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A1 COL4A3 SCUBE1 FBN1 FN1	7.98e-05	140	45	5	M587
Pathway	WP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING	DLL4 DLL1 NOTCH2	8.43e-05	27	45	3	M39545
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A1 COL4A3 FBN1 FN1	9.83e-05	76	45	4	MM14867
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A1 COL4A3 LAMA2	1.16e-04	30	45	3	M27216
Pathway	WP_BREAST_CANCER_PATHWAY	DLL4 CSNK2B DLL1 NOTCH2 AXIN2	1.25e-04	154	45	5	M39739
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A1 COL4A3 FN1	1.41e-04	32	45	3	MM14924
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_FIBRINOLYTIC_SYSTEM_C1INH	MASP1 C1R	1.48e-04	6	45	2	M47882
Pathway	KEGG_MEDICUS_PATHOGEN_SARS_COV_2_S_TO_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE	C1QA C1R	1.48e-04	6	45	2	M47783
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A1 COL4A3 FBN1 FN1	1.52e-04	85	45	4	M16441
Pathway	REACTOME_SIGNALING_BY_NOTCH2	DLL4 DLL1 NOTCH2	1.55e-04	33	45	3	M604
Pathway	WP_CANCER_PATHWAYS	COL4A1 COL4A3 FN1 DLL4 LAMA2 DLL1 NOTCH2 AXIN2	1.77e-04	507	45	8	M48302
Pathway	REACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT	DLL4 DLL1	2.07e-04	7	45	2	M27199
Pathway	KEGG_MEDICUS_ENV_FACTOR_E2_TO_NUCLEAR_INITIATED_ESTROGEN_SIGNALING_PATHWAY	DLL4 DLL1	2.07e-04	7	45	2	M47805
Pathway	WP_SMALL_CELL_LUNG_CANCER	COL4A1 COL4A3 FN1 LAMA2	2.43e-04	96	45	4	M39834
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C1QA C1R	2.76e-04	8	45	2	M47872
Pathway	KEGG_MEDICUS_REFERENCE_NOTCH_LIGAND_UBIQUITYLATION	DLL4 DLL1	3.54e-04	9	45	2	M47866
Pathway	WP_NOTCH_SIGNALING_WP268	DLL4 DLL1 NOTCH2	3.93e-04	45	45	3	M39571
Pathway	WP_NOTCH_SIGNALING_PATHWAY	DLL4 DLL1 NOTCH2	4.19e-04	46	45	3	MM15971
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A1 COL4A3	4.41e-04	10	45	2	M22040
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A1 COL4A3	4.41e-04	10	45	2	MM1560
Pathway	KEGG_NOTCH_SIGNALING_PATHWAY	DLL4 DLL1 NOTCH2	4.47e-04	47	45	3	M7946
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	FBN1 BMP10 CHRDL1 LTBP2	5.33e-04	118	45	4	MM15588
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A1 COL4A3	5.38e-04	11	45	2	M15422
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	FBN1 FN1 MATN3 CHRDL1	5.68e-04	120	45	4	MM14982
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	FBN1 FN1 MATN3 CHRDL1	6.43e-04	124	45	4	M27285
Pathway	BIOCARTA_HES_PATHWAY	DLL1 NOTCH2	6.44e-04	12	45	2	MM1562
Pathway	BIOCARTA_HES_PATHWAY	DLL1 NOTCH2	6.44e-04	12	45	2	M22042
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A1 COL4A3	6.44e-04	12	45	2	MM1526
Pathway	BIOCARTA_CLASSIC_PATHWAY	C1QA C1R	6.44e-04	12	45	2	MM1368
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	MASP1 C1QA C1R	6.73e-04	54	45	3	MM14655
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A1 COL4A3	7.60e-04	13	45	2	MM1347
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A1 COL4A3	7.60e-04	13	45	2	M12950
Pathway	REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER	HDAC6 DLL4 DLL1	8.30e-04	58	45	3	M29616
Pathway	WP_COMPLEMENT_AND_COAGULATION_CASCADES	MASP1 C1QA C1R	8.30e-04	58	45	3	M39649
Pathway	WP_DENGUE2_INTERACTIONS_WITH_COMPLEMENT_AND_COAGULATION_CASCADES	MASP1 C1QA C1R	8.72e-04	59	45	3	M48343
Pathway	PID_NOTCH_PATHWAY	DLL4 DLL1 NOTCH2	8.72e-04	59	45	3	M17
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A1 COL4A3	8.85e-04	14	45	2	MM1458
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A1 COL4A3	8.85e-04	14	45	2	M6487
Pathway	WP_NOTCH_SIGNALING_WP61	DLL4 DLL1 NOTCH2	9.61e-04	61	45	3	M39540
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A1 COL4A3	1.02e-03	15	45	2	MM14922
Pathway	REACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER	DLL4 DLL1	1.02e-03	15	45	2	M27202
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	COL4A1 COL4A3	1.02e-03	15	45	2	M27161
Pathway	BIOCARTA_CLASSIC_PATHWAY	C1QA C1R	1.02e-03	15	45	2	M7146
Pathway	KEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY	DLL4 DLL1	1.16e-03	16	45	2	M47424
Pathway	PID_INTEGRIN5_PATHWAY	FBN1 FN1	1.31e-03	17	45	2	M212
Pathway	WP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION	DLL4 DLL1	1.31e-03	17	45	2	M39389
Pathway	KEGG_COMPLEMENT_AND_COAGULATION_CASCADES	MASP1 C1QA C1R	1.37e-03	69	45	3	M16894
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A1 COL4A3	1.48e-03	18	45	2	M27164
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A1 COL4A3	1.48e-03	18	45	2	MM14882
Pathway	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	MASP1 C1QA C1R	1.49e-03	71	45	3	M1078
Pathway	WP_OVERVIEW_OF_NANOPARTICLE_EFFECTS	COL4A1 FN1	1.65e-03	19	45	2	M39473
Pathway	REACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS	COL4A1 MASP1	1.65e-03	19	45	2	M27221
Pathway	REACTOME_SIGNALING_BY_NOTCH3	DLL4 DLL1	1.65e-03	19	45	2	MM15594
Pathway	PID_AVB3_INTEGRIN_PATHWAY	COL4A1 COL4A3 FN1	1.68e-03	74	45	3	M160
Pathway	REACTOME_SIGNALING_BY_NOTCH1	HDAC6 DLL4 DLL1	1.68e-03	74	45	3	M616
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	FBN1 BMP10 CHRDL1 LTBP2	1.70e-03	161	45	4	M27871
Pathway	BIOCARTA_AMI_PATHWAY	COL4A1 COL4A3	1.83e-03	20	45	2	M15394
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A1 COL4A3	1.83e-03	20	45	2	MM15061
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	MASP1 C1QA C1R	2.10e-03	80	45	3	M6121
Pathway	WP_DELTANOTCH_SIGNALING_PATHWAY	DLL4 DLL1 NOTCH2	2.26e-03	82	45	3	MM15922
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A1 COL4A3	2.42e-03	23	45	2	M15997
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A1 COL4A3	2.42e-03	23	45	2	MM1427
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	COL4A1 FN1 LAMA2	2.42e-03	84	45	3	M3228
Pathway	REACTOME_COMPLEMENT_CASCADE	MASP1 C1QA C1R	2.42e-03	84	45	3	MM14653
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL4A1 FN1 LAMA2	2.42e-03	84	45	3	M7098
Pathway	REACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS	DLL4 DLL1	2.85e-03	25	45	2	M27879
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FBN1 LTBP2	2.85e-03	25	45	2	M39713
Pathway	REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY	HDAC6 NOTCH2	3.57e-03	28	45	2	M6177
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	FN1 LAMA2	4.09e-03	30	45	2	M27772
Pathway	REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS	DLL4 DLL1	4.37e-03	31	45	2	M592
Pathway	REACTOME_SIGNALING_BY_BMP	BMP10 CHRDL1	4.37e-03	31	45	2	M1662
Pathway	REACTOME_SIGNALING_BY_BMP	BMP10 CHRDL1	4.37e-03	31	45	2	MM14789
Pathway	WP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY	MASP1 C1QA C1R	4.66e-03	106	45	3	M42535
Pathway	WP_7Q1123_COPY_NUMBER_VARIATION_SYNDROME	LIMK1 FBN1 HDAC6	4.66e-03	106	45	3	M40052
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	COL4A1 COL4A3 LIMK1 KRTAP19-7 CSNK2B KRTAP24-1	4.96e-03	502	45	6	MM14537
Pathway	REACTOME_COMPLEMENT_CASCADE	MASP1 C1QA C1R	5.85e-03	115	45	3	M19752
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	DLL4 DLL1 NOTCH2	6.28e-03	118	45	3	M39852
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A1 COL4A3	6.51e-03	38	45	2	MM14969
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	FBN1 LTBP2	6.51e-03	38	45	2	MM14874
Pathway	REACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION	C1QA C1R	6.85e-03	39	45	2	MM17212
Pubmed	Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.	COL4A1 COL4A3 FBN1 FN1	1.17e-09	10	55	4	9415455
Pubmed	Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.	COL4A1 COL4A3 FN1 LAMA2	3.96e-09	13	55	4	9833687
Pubmed	Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.	DLL4 DLL1 NOTCH2 AXIN2	1.31e-08	17	55	4	39315665
Pubmed	Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.	DLL4 DLL1 NOTCH2	1.50e-08	4	55	3	32820046
Pubmed	Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands.	DLL4 DLL1 NOTCH2	1.50e-08	4	55	3	28319044
Pubmed	Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.	DLL4 DLL1 NOTCH2	3.73e-08	5	55	3	21726900
Pubmed	Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.	DLL4 DLL1 NOTCH2	3.73e-08	5	55	3	30181175
Pubmed	Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19.	MASP1 C1QA C1R	7.46e-08	6	55	3	10878362
Pubmed	Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.	DLL4 DLL1 NOTCH2	7.46e-08	6	55	3	19217325
Pubmed	Promotion of tumor cell migration by extracellular matrix proteins in human pancreatic cancer.	COL4A1 FN1 LAMA2	7.46e-08	6	55	3	19893454
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL4A1 COL4A3 FBN1 FN1 LAMA2 C1QA	7.58e-08	135	55	6	28675934
Pubmed	Substrate specificities of recombinant mannan-binding lectin-associated serine proteases-1 and -2.	MASP1 C1QA C1R	1.30e-07	7	55	3	11527969
Pubmed	GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.	DLL4 DLL1 NOTCH2	1.30e-07	7	55	3	32060138
Pubmed	Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.	DLL4 DLL1 NOTCH2	1.30e-07	7	55	3	27576369
Pubmed	Hypoplastic basement membrane of the lens anlage in the inheritable lens aplastic mouse (lap mouse).	COL4A1 COL4A3 FN1	1.30e-07	7	55	3	10716744
Pubmed	The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.	DLL4 DLL1 NOTCH2	1.30e-07	7	55	3	30289388
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL4A1 COL4A3 FBN1 FN1 LAMA2 COLQ	1.59e-07	153	55	6	25037231
Pubmed	Appearance and persistence of fibronectin in cartilage. Specific interaction of fibronectin with collagen type II.	COL4A1 COL4A3 FN1	2.08e-07	8	55	3	3997552
Pubmed	Mice develop normally without tenascin.	COL4A1 COL4A3 FN1	2.08e-07	8	55	3	1383086
Pubmed	Molecular properties of wild-type and mutant betaIG-H3 proteins.	COL4A1 COL4A3 FN1	2.08e-07	8	55	3	11867580
Pubmed	Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.	DLL4 DLL1 COLQ NOTCH2 AXIN2	2.59e-07	86	55	5	35103284
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL4A1 FBN1 FN1 LAMA2 LTBP2 COLQ	2.67e-07	167	55	6	22159717
Pubmed	Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.	DLL4 DLL1 NOTCH2	3.12e-07	9	55	3	16245338
Pubmed	Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling.	COL4A1 COL4A3 KLF5	3.12e-07	9	55	3	12101409
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL4A1 COL4A3 FBN1 FN1 LAMA2 LTBP2	3.52e-07	175	55	6	28071719
Pubmed	Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.	DLL4 DLL1 NOTCH2	4.46e-07	10	55	3	23665443
Pubmed	Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.	DLL4 DLL1 NOTCH2	4.46e-07	10	55	3	24015274
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	COL4A1 FBN1 FN1 LAMA2 LTBP2	4.74e-07	97	55	5	27559042
Pubmed	The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.	DLL4 KLF5 DLL1 NOTCH2 AXIN2	5.51e-07	100	55	5	24859004
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A1 COL4A3 FN1	6.12e-07	11	55	3	7500359
Pubmed	Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.	COL4A1 COL4A3 LAMA2	8.15e-07	12	55	3	26794322
Pubmed	Matrilin-2 interacts with itself and with other extracellular matrix proteins.	COL4A1 COL4A3 FN1	8.15e-07	12	55	3	12180907
Pubmed	Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.	DLL4 DLL1 NOTCH2	8.15e-07	12	55	3	15465494
Pubmed	Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia.	FN1 DLL4 DLL1 NOTCH2	1.03e-06	48	55	4	35247391
Pubmed	Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.	DLL4 DLL1 NOTCH2	1.06e-06	13	55	3	11578869
Pubmed	Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation.	DLL1 NOTCH2 AXIN2	1.06e-06	13	55	3	18708576
Pubmed	Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.	DLL4 DLL1 NOTCH2 AXIN2	1.22e-06	50	55	4	27510977
Pubmed	Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.	DLL4 DLL1 NOTCH2	1.35e-06	14	55	3	14757642
Pubmed	Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.	DLL4 DLL1 NOTCH2	1.68e-06	15	55	3	12971992
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A1 COL4A3 LAMA2	1.68e-06	15	55	3	10625553
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	COL4A1 COL4A3 LAMA2	1.68e-06	15	55	3	9264260
Pubmed	Expression of Notch pathway components in fetal and adult mouse small intestine.	DLL4 DLL1 NOTCH2	2.07e-06	16	55	3	12617809
Pubmed	Craniofacial malformation in R-spondin2 knockout mice.	FN1 RSPO2 AXIN2	2.07e-06	16	55	3	19233133
Pubmed	An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.	DLL4 DLL1 NOTCH2	2.07e-06	16	55	3	17273555
Pubmed	Fibronectin binds to the C1q component of complement.	FN1 C1QA	2.46e-06	2	55	2	6981115
Pubmed	Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism.	DLL1 NOTCH2	2.46e-06	2	55	2	14660750
Pubmed	Fibrillin assembly requires fibronectin.	FBN1 FN1	2.46e-06	2	55	2	19037100
Pubmed	Suppression of Th2 cell development by Notch ligands Delta1 and Delta4.	DLL4 DLL1	2.46e-06	2	55	2	18209061
Pubmed	Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development.	DLL4 DLL1	2.46e-06	2	55	2	16393955
Pubmed	Direct comparison of Dll1- and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes.	DLL4 DLL1	2.46e-06	2	55	2	20548034
Pubmed	Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease.	FBN1 AXIN2	2.46e-06	2	55	2	28069701
Pubmed	Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome.	COL4A1 FN1	2.46e-06	2	55	2	34424299
Pubmed	Isolation and characterization of the notch ligand delta4.	DLL4 DLL1	2.46e-06	2	55	2	11035934
Pubmed	Selective integrin subunit reduction disrupts fibronectin extracellular matrix deposition and fibrillin 1 gene expression.	FBN1 FN1	2.46e-06	2	55	2	22782528
Pubmed	DLL1- and DLL4-Mediated Notch Signaling Is Essential for Adult Pancreatic Islet Homeostasis.	DLL4 DLL1	2.46e-06	2	55	2	32029480
Pubmed	Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo.	DLL4 DLL1	2.46e-06	2	55	2	15146182
Pubmed	Induction of T-cell development by Delta-like 4-expressing fibroblasts.	DLL4 DLL1	2.46e-06	2	55	2	23988616
Pubmed	In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects.	DLL4 DLL1	2.46e-06	2	55	2	15728481
Pubmed	Fibrillin-1 microfibril deposition is dependent on fibronectin assembly.	FBN1 FN1	2.46e-06	2	55	2	18653538
Pubmed	Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.	FBN1 LTBP2	2.46e-06	2	55	2	24867584
Pubmed	Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice.	DLL4 DLL1	2.46e-06	2	55	2	31934853
Pubmed	Complex contributions of fibronectin to initiation and maturation of microfibrils.	FBN1 FN1	2.46e-06	2	55	2	24070235
Pubmed	Dengue virus up-regulates expression of notch ligands Dll1 and Dll4 through interferon-β signalling pathway.	DLL4 DLL1	2.46e-06	2	55	2	25041739
Pubmed	Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.	DLL4 DLL1 NOTCH2	2.50e-06	17	55	3	18694942
Pubmed	Segmental expression of Notch and Hairy genes in nephrogenesis.	DLL4 DLL1 NOTCH2	2.50e-06	17	55	3	15821257
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	COL4A1 FBN1 FN1 LAMA2 C1QA LTBP2	2.68e-06	248	55	6	24006456
Pubmed	Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.	DLL4 DLL1 NOTCH2	3.00e-06	18	55	3	18093989
Pubmed	ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.	COL4A1 FBN1 FN1	3.00e-06	18	55	3	39040056
Pubmed	RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.	DLL4 DLL1 NOTCH2	3.00e-06	18	55	3	15689374
Pubmed	RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.	DLL4 DLL1 NOTCH2	3.56e-06	19	55	3	20335360
Pubmed	Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.	DLL4 DLL1 NOTCH2	3.56e-06	19	55	3	16518823
Pubmed	Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.	DLL4 DLL1 NOTCH2	3.56e-06	19	55	3	25691540
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	COL4A1 FBN1 FN1 LAMA2 LTBP2	3.58e-06	146	55	5	27068509
Pubmed	Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.	BMP10 DLL4 NOTCH2	4.19e-06	20	55	3	23314057
Pubmed	Tie2 regulates endocardial sprouting and myocardial trabeculation.	FN1 BMP10 DLL4 DLL1	4.23e-06	68	55	4	31112136
Pubmed	Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.	DLL4 DLL1 NOTCH2	4.88e-06	21	55	3	28656980
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	LAMA2 DLL1 AXIN2	5.64e-06	22	55	3	28334989
Pubmed	Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.	DLL4 DLL1 NOTCH2	5.64e-06	22	55	3	21750033
Pubmed	Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling.	COL4A1 FN1 AXIN2	5.64e-06	22	55	3	24000064
Pubmed	Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.	DLL4 DLL1 NOTCH2	6.48e-06	23	55	3	14701881
Pubmed	Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.	DLL4 DLL1 NOTCH2	6.48e-06	23	55	3	19897741
Pubmed	Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.	DLL4 DLL1 NOTCH2	6.48e-06	23	55	3	24337118
Pubmed	Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.	DLL4 DLL1 NOTCH2	6.48e-06	23	55	3	36239412
Pubmed	Helicobacter pylori Infection of Gastric Epithelial Cells Affects NOTCH Pathway In Vitro.	DLL4 NOTCH2	7.36e-06	3	55	2	27073072
Pubmed	Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.	COL4A1 COL4A3	7.36e-06	3	55	2	3025878
Pubmed	Identification of an Altered Matrix Signature in Kidney Aging and Disease.	COL4A1 COL4A3	7.36e-06	3	55	2	34049963
Pubmed	Protein kinase CK2 regulates CDC25B phosphatase activity.	CSNK2B CDC25B	7.36e-06	3	55	2	12527891
Pubmed	C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.	C1QA C1R	7.36e-06	3	55	2	34155115
Pubmed	Notch signaling confers antigen-presenting cell functions on mast cells.	DLL1 NOTCH2	7.36e-06	3	55	2	19130928
Pubmed	Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines.	DLL4 DLL1	7.36e-06	3	55	2	12684674
Pubmed	PDGFRβ-positive cell-mediated post-stroke remodeling of fibronectin and laminin α2 for tissue repair and functional recovery.	FN1 LAMA2	7.36e-06	3	55	2	36514952
Pubmed	Analysis of human C1q by combined bottom-up and top-down mass spectrometry: detailed mapping of post-translational modifications and insights into the C1r/C1s binding sites.	C1QA C1R	7.36e-06	3	55	2	20008834
Pubmed	The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells.	COL4A1 FN1	7.36e-06	3	55	2	22919069
Pubmed	O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells.	DLL4 NOTCH2	7.36e-06	3	55	2	33351914
Pubmed	KLF13 restrains Dll4-muscular Notch2 axis to improve the muscle atrophy.	DLL4 NOTCH2	7.36e-06	3	55	2	38973459
Pubmed	Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.	DLL4 DLL1	7.36e-06	3	55	2	21372153
Pubmed	T/B lineage choice occurs prior to intrathymic Notch signaling.	FN1 DLL1	7.36e-06	3	55	2	15845899
Pubmed	Lack of Delta like 1 and 4 expressions in nude thymus anlages.	DLL4 DLL1	7.36e-06	3	55	2	16095582
Pubmed	Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.	DLL1 NOTCH2	7.36e-06	3	55	2	11823422
Pubmed	Correlation of extracellular matrix-related gene expression with objective Fuchs endothelial corneal dystrophy severity.	COL4A1 FN1	7.36e-06	3	55	2	30578652
Interaction	DCN interactions	COL4A1 COL4A3 FBN1 FN1 C1QA	8.39e-08	43	52	5	int:DCN
Interaction	C1S interactions	FN1 C1QA C1R	1.92e-06	10	52	3	int:C1S
Interaction	FBLN2 interactions	COL4A1 COL4A3 FBN1 FN1	2.52e-05	66	52	4	int:FBLN2
Interaction	TGFBI interactions	COL4A1 COL4A3 FN1	3.58e-05	25	52	3	int:TGFBI
Interaction	COL4A2 interactions	COL4A1 FN1 CSNK2B COLQ	4.18e-05	75	52	4	int:COL4A2
Cytoband	19q13.1	FCGBP ZFP36	2.01e-03	55	55	2	19q13.1
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	MASP1 C1R SEZ6L2	1.97e-04	57	36	3	1179
GeneFamily	Complement system\|Sushi domain containing	C1QA C1R	2.33e-03	36	36	2	492
GeneFamily	Collagens	COL4A1 COL4A3	3.78e-03	46	36	2	490
GeneFamily	Endogenous ligands	FN1 BMP10 RSPO2	1.15e-02	237	36	3	542
GeneFamily	Keratin associated proteins	KRTAP19-7 KRTAP24-1	1.99e-02	109	36	2	619
Coexpression	NABA_CORE_MATRISOME	COL4A1 ZP1 COL4A3 FBN1 FN1 OTOGL MATN3 LAMA2 RSPO2 LTBP2 TECTA COLQ	3.31e-13	270	55	12	MM17057
Coexpression	NABA_MATRISOME	COL4A1 ZP1 COL4A3 MASP1 SCUBE1 FBN1 FN1 BMP10 OTOGL CCBE1 MATN3 LAMA2 RSPO2 C1QA CHRDL1 LTBP2 TECTA COLQ	1.09e-12	1008	55	18	MM17056
Coexpression	NABA_ECM_GLYCOPROTEINS	ZP1 FBN1 FN1 OTOGL MATN3 LAMA2 RSPO2 LTBP2 TECTA COLQ	7.33e-12	191	55	10	MM17059
Coexpression	NABA_CORE_MATRISOME	COL4A1 ZP1 COL4A3 FBN1 FN1 MATN3 LAMA2 RSPO2 LTBP2 TECTA COLQ	1.10e-11	275	55	11	M5884
Coexpression	NABA_MATRISOME	COL4A1 ZP1 COL4A3 MASP1 SCUBE1 FBN1 FN1 BMP10 CCBE1 MATN3 LAMA2 RSPO2 C1QA CHRDL1 LTBP2 TECTA COLQ	1.75e-11	1026	55	17	M5889
Coexpression	NABA_ECM_GLYCOPROTEINS	ZP1 FBN1 FN1 MATN3 LAMA2 RSPO2 LTBP2 TECTA COLQ	2.87e-10	196	55	9	M3008
Coexpression	BOQUEST_STEM_CELL_UP	PRR16 FBN1 BHMT2 LAMA2 CHRDL1 C1R LTBP2 NOTCH2	7.06e-08	261	55	8	M1834
Coexpression	HAY_BONE_MARROW_STROMAL	COL4A1 SCUBE1 FBN1 FN1 OTOGL CCBE1 MATN3 CHRDL1 C1R LTBP2 ZFP36	4.64e-07	767	55	11	M39209
Coexpression	NABA_BASEMENT_MEMBRANES	COL4A1 COL4A3 LAMA2 COLQ	1.50e-06	40	55	4	M5887
Coexpression	AIZARANI_LIVER_C21_STELLATE_CELLS_1	COL4A1 MASP1 FBN1 CCBE1 C1R ZFP36	3.26e-06	194	55	6	M39122
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	COL4A1 FBN1 FN1 MATN3 LAMA2 NOTCH2	3.89e-06	200	55	6	M5930
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL4 DLL1 NOTCH2	4.80e-06	16	55	3	MM1296
Coexpression	FUKUSHIMA_TNFSF11_TARGETS	DLL4 DLL1 NOTCH2	4.80e-06	16	55	3	M2207
Coexpression	HOSHIDA_LIVER_CANCER_SUBCLASS_S1	COL4A1 FBN1 FCGBP KLF5 LTBP2 CDC25B	9.78e-06	235	55	6	M5311
Coexpression	HU_FETAL_RETINA_FIBROBLAST	COL4A1 SCUBE1 FBN1 FN1 C1R ZFP36 NOTCH2	1.55e-05	385	55	7	M39264
Coexpression	VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP	COL4A1 FBN1 FN1 LAMA2 LTBP2	3.61e-05	178	55	5	M17079
Coexpression	CUI_DEVELOPING_HEART_VASCULAR_ENDOTHELIAL_CELL	C1R LTBP2 SEZ6L2 ZFP36 ZFY	5.30e-05	193	55	5	M39321
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR	FN1 CCBE1 LTBP2	5.46e-05	35	55	3	MM17054
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	FBN1 LAMA2 LTBP2	5.46e-05	35	55	3	M11788
Coexpression	CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN	FBN1 LAMA2 LTBP2	5.94e-05	36	55	3	MM1212
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN	FBN1 POLR1A FN1 LTBP2 NOTCH2	6.28e-05	200	55	5	M9657
Coexpression	GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_DN	COL4A1 FBN1 POLR1A C1QA LTBP2	6.28e-05	200	55	5	M4354
Coexpression	BROWNE_HCMV_INFECTION_48HR_DN	MASP1 FN1 MOCS3 LAMA2 LTBP2 SH2D1A ZFP36	6.44e-05	482	55	7	M12144
Coexpression	PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP	COL4A1 FBN1 FN1 C1QA C1R	8.09e-05	211	55	5	M12225
Coexpression	VANHARANTA_UTERINE_FIBROID_UP	COL4A1 FN1 LTBP2	1.09e-04	44	55	3	M18274
Coexpression	TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP	COL4A1 FBN1 FN1	1.33e-04	47	55	3	M7585
Coexpression	TRAVAGLINI_LUNG_ALVEOLAR_EPITHELIAL_TYPE_1_CELL	COL4A1 COL4A3 FN1 CCBE1 MATN3 ZFP36	1.66e-04	391	55	6	M41659
Coexpression	HALLMARK_COAGULATION	FBN1 FN1 C1QA C1R	2.04e-04	138	55	4	M5946
Coexpression	DESCARTES_FETAL_LUNG_STROMAL_CELLS	PRR16 LAMA2 RSPO2	2.24e-04	56	55	3	M40248
Coexpression	DESCARTES_FETAL_KIDNEY_MESANGIAL_CELLS	CCBE1 LAMA2 SEZ6L2	2.24e-04	56	55	3	M40224
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPERIC	COL4A1 PRR16 FBN1 FN1 LAMA2 ZFP36 NOTCH2 AXIN2	2.39e-04	795	55	8	M39050
Coexpression	DESCARTES_FETAL_KIDNEY_STROMAL_CELLS	FBN1 CHRDL1 C1R LTBP2	2.53e-04	146	55	4	M40222
Coexpression	RUBENSTEIN_SKELETAL_MUSCLE_FBN1_FAP_CELLS	FBN1 FN1 CHRDL1 C1R NOTCH2	3.49e-04	289	55	5	M41750
Coexpression	MA_RAT_AGING_DN	COL4A1 FBN1 FN1 ZFP36	3.66e-04	161	55	4	M46419
Coexpression	VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	COL4A3 DLL4 DLL1 NOTCH2	3.84e-04	163	55	4	M12112
Coexpression	DESCARTES_FETAL_ADRENAL_LYMPHOID_CELLS	YWHAH-AS1 DTHD1 SH2D1A CD96	3.93e-04	164	55	4	M40154
Coexpression	MA_RAT_AGING_DN	COL4A1 FBN1 FN1 ZFP36	4.50e-04	170	55	4	MM16097
Coexpression	GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP	COL4A1 FN1 ZFY	4.71e-04	72	55	3	MM1131
CoexpressionAtlas	placenta	COL4A1 FBN1 FN1 DLL4 MATN3 LAMA2 RSPO2	2.16e-05	349	52	7	placenta
CoexpressionAtlas	Stromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2	FBN1 FN1 CHRDL1 C1R	5.59e-05	85	52	4	GSM777067_100
CoexpressionAtlas	Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5	FBN1 FN1 CHRDL1 C1R	6.12e-05	87	52	4	GSM777050_100
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	FBN1 FN1 LAMA2 C1R	9.36e-05	97	52	4	GSM777046_100
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_reference_BronchSmoothMuscl_top-relative-expression-ranked_1000	PRR16 MASP1 FBN1 FN1 CCBE1 BHMT2 RSPO2 C1R LTBP2 CD96	1.14e-04	981	52	10	PCBC_ctl_BronchSmoothMuscl_1000
CoexpressionAtlas	Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4	COL4A1 FBN1 FN1 CHRDL1 C1R LTBP2 ZFP36	1.15e-04	455	52	7	GSM777055_500
CoexpressionAtlas	JC_fibro_top-relative-expression-ranked_500_k-means-cluster#3	PRR16 FBN1 FN1 BHMT2 C1R	1.47e-04	206	52	5	JC_fibro_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#5	VRK1 SCUBE1 KLF5 CDC25B DLL1	1.68e-04	212	52	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K5
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500	MASP1 FBN1 CCBE1 LTBP2 CDC25B DLL1 ZFP36	1.82e-04	490	52	7	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	COL4A1 SCUBE1 FBN1 FN1 LAMA2 NOTCH2	2.26e-04	356	52	6	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000	FBN1 KLF5 LAMA2 C1QA CHRDL1 LTBP2	2.74e-04	369	52	6	gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#1_top-relative-expression-ranked_500	FBN1 KLF5 LAMA2 C1QA CHRDL1	2.98e-04	240	52	5	gudmap_kidney_adult_RenalCapsule_k1_500
CoexpressionAtlas	alpha beta T cells, T.DP69+.Th, 4+ 8+ TCRlo/int 69+, Thymus, avg-3	COLQ SH2D1A CD96	3.69e-04	57	52	3	GSM399394_100
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A1 MASP1 SCUBE1 FBN1 FN1 CCBE1 LAMA2 CHRDL1 LTBP2	1.22e-12	181	55	9	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	2.40e-12	195	55	9	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	2.75e-12	198	55	9	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 MASP1 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2 DLL1	3.01e-12	200	55	9	8ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCell	-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 LTBP2 SH2D1A CD96	5.57e-11	179	55	8	e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	7.56e-11	186	55	8	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR16 FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.02e-10	193	55	8	5bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCell	21-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL4A1 PRR16 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R	1.06e-10	194	55	8	749dd8113ef260e00facac09de9861d61725124a
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A3 PRR16 FBN1 FN1 LAMA2 C1R LTBP2 NOTCH2	1.10e-10	195	55	8	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.10e-10	195	55	8	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A1 FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	1.10e-10	195	55	8	1236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.15e-10	196	55	8	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	1.20e-10	197	55	8	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.24e-10	198	55	8	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	PRR16 FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.30e-10	199	55	8	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.30e-10	199	55	8	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 C1R LTBP2	1.35e-10	200	55	8	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	FBN1 FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	1.35e-10	200	55	8	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	Adult-Mesenchymal-chondrocyte-D231\|Adult / Lineage, Cell type, age group and donor	FBN1 FN1 DLL4 CCBE1 LAMA2 LTBP2 SEZ6L2	1.32e-09	164	55	7	2ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell	-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	PRR16 FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 LTBP2	1.62e-09	169	55	7	8ebe9a88111c53a09c25a7b6a164a0a17880458d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR16 MASP1 FBN1 CCBE1 LAMA2 CHRDL1 LTBP2	2.07e-09	175	55	7	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	MASP1 FBN1 BHMT2 LAMA2 CHRDL1 C1R LTBP2	2.15e-09	176	55	7	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A1 PRR16 SCUBE1 FBN1 CCBE1 LAMA2 LTBP2	2.52e-09	180	55	7	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR16 LIMK1 FBN1 FN1 LAMA2 ZNF518B COLQ	3.05e-09	185	55	7	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR16 LIMK1 FBN1 FN1 LAMA2 ZNF518B COLQ	3.05e-09	185	55	7	049d793d043d5d434f143025de49dd210d18756c
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR16 LIMK1 FBN1 FN1 LAMA2 ZNF518B COLQ	3.05e-09	185	55	7	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 LTBP2	3.28e-09	187	55	7	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 LTBP2	3.67e-09	190	55	7	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	3.94e-09	192	55	7	b9e4585bea280ca0ae159f0c6a2bf7b88a15a6e6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR16 MASP1 FN1 CCBE1 LAMA2 C1R LTBP2	4.23e-09	194	55	7	8fae8061b350336299aa81f378e07deadbd55123
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 LTBP2	4.23e-09	194	55	7	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	COL4A1 COL4A3 FBN1 FN1 LAMA2 C1R LTBP2	4.23e-09	194	55	7	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2	4.23e-09	194	55	7	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR16 MASP1 FN1 CCBE1 LAMA2 C1R LTBP2	4.23e-09	194	55	7	4d7d24390fdb379f943ddcc70a63f23955e10163
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A1 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	4.39e-09	195	55	7	78cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	4.39e-09	195	55	7	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 LTBP2	4.39e-09	195	55	7	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 LTBP2	4.39e-09	195	55	7	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	4.39e-09	195	55	7	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 MASP1 FBN1 CCBE1 LAMA2 LTBP2 USP35	4.39e-09	195	55	7	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	COL4A1 PRR16 CCBE1 LAMA2 CHRDL1 C1R LTBP2	4.55e-09	196	55	7	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	4.55e-09	196	55	7	9737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 C1R	4.55e-09	196	55	7	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	4.55e-09	196	55	7	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRR16 FBN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	4.55e-09	196	55	7	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	4.71e-09	197	55	7	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	PRR16 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	4.71e-09	197	55	7	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	COL4A1 PRR16 CCBE1 LAMA2 CHRDL1 C1R LTBP2	4.71e-09	197	55	7	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	4.71e-09	197	55	7	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	tumor_Lung-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lung / Location, Cell class and cell subclass	FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	4.88e-09	198	55	7	2d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 SCUBE1 FBN1 CCBE1 LAMA2 CHRDL1 LTBP2	4.88e-09	198	55	7	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	distal-mesenchymal-Myofibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRR16 FBN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	4.88e-09	198	55	7	beef5075ba6dcd4d0a447bc4e57efcaf2e93c546
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	PRR16 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	4.88e-09	198	55	7	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 C1R	4.88e-09	198	55	7	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	PRR16 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	4.88e-09	198	55	7	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FN1 CCBE1 LAMA2 C1R LTBP2 AXIN2	4.88e-09	198	55	7	08d393853e195a7eacace454153e425a273e2d23
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2	4.88e-09	198	55	7	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2	5.05e-09	199	55	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	COL4A1 FBN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.05e-09	199	55	7	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	ASK452-Mesenchymal-Fibroblast\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.05e-09	199	55	7	4d0bf2a4bd97e5a3bfe4570a201cc21bb9c4c1f6
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 COL4A3 SCUBE1 FBN1 LAMA2 CHRDL1 C1R	5.05e-09	199	55	7	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	ASK452-Mesenchymal\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.05e-09	199	55	7	93e85e3731a9ece9aee3eb82c5dfdad331ee62d6
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.05e-09	199	55	7	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 C1R	5.05e-09	199	55	7	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	cellseq-Mesenchymal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A1 FBN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL4A1 FBN1 FN1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	2022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 PRR16 FBN1 FN1 CCBE1 LAMA2 LTBP2	5.23e-09	200	55	7	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 LTBP2	5.23e-09	200	55	7	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCell	Bronchus_Control_(B.)-Stromal-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL4A1 FBN1 FN1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	69b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	58c5870030192b337e7d883044948634fcd17d2c
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL4A1 PRR16 FBN1 MATN3 LAMA2 C1R LTBP2	5.23e-09	200	55	7	4f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCell	proximal-mesenchymal-Adventitial_Fibroblast-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	05486d86868f6a93429226063cca270f00dd8714
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	COL4A1 PRR16 FBN1 MATN3 LAMA2 C1R LTBP2	5.23e-09	200	55	7	ca777a7d001848f6d01c613ff2bda7e4f3e20521
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 PRR16 FBN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	proximal-3-mesenchymal-Adventitial_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	869d45b71efd395d050873db5fee2ed0443d5e6f
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 LTBP2	5.23e-09	200	55	7	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A1 PRR16 FBN1 FN1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 MASP1 FN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	251fd2923f108cd2086961d897244b392c32ad54
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 CCBE1 LAMA2 RSPO2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRR16 FBN1 FN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	b441b3771fb7d9ee7b7a104afc35e466aace2da2
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 FN1 CCBE1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	fd92d8250c6ad1e8bb46b303ac37f8dcf80387d8
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRR16 MASP1 FN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	07641f476cb1a131c2a50258b88cc13bb38c8379
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	PRR16 MASP1 FN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 FN1 CCBE1 LAMA2 RSPO2 LTBP2	5.23e-09	200	55	7	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A1 FBN1 FN1 LAMA2 CHRDL1 C1R LTBP2	5.23e-09	200	55	7	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR16 MASP1 FN1 CCBE1 LAMA2 C1R LTBP2	5.23e-09	200	55	7	d0c00cdd52c2e001aec9b935f4e981ba77d0386a
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRR16 SCUBE1 OTOGL CCBE1 LAMA2 LTBP2	3.40e-08	152	55	6	621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	PRR16 FBN1 FN1 DLL4 LAMA2 LTBP2	4.45e-08	159	55	6	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRR16 SCUBE1 FBN1 CCBE1 LAMA2 LTBP2	7.35e-08	173	55	6	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 FBN1 CCBE1 LAMA2 CHRDL1 LTBP2	7.86e-08	175	55	6	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 FN1 BHMT2 LAMA2 CHRDL1 C1R	8.13e-08	176	55	6	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 FN1 BHMT2 LAMA2 CHRDL1 C1R	8.13e-08	176	55	6	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FBN1 CCBE1 LAMA2 RSPO2 CHRDL1 LTBP2	8.99e-08	179	55	6	10fadbaa1b6d21cbf9f354d717cc4c225619f4fd
ToppCell	390C-Fibroblasts-Fibroblast-G\|390C / Donor, Lineage, Cell class and subclass (all cells)	MASP1 FN1 BHMT2 RSPO2 C1R LTBP2	9.29e-08	180	55	6	137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell	390C-Fibroblasts-Fibroblast-G-\|390C / Donor, Lineage, Cell class and subclass (all cells)	MASP1 FN1 BHMT2 RSPO2 C1R LTBP2	9.29e-08	180	55	6	cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRR16 MASP1 FN1 CCBE1 LAMA2 LTBP2	9.60e-08	181	55	6	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	COL4A1 FBN1 FN1 MATN3 C1R LTBP2	9.60e-08	181	55	6	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
Computational	ECM and collagens.	COL4A1 PRR16 FBN1 FN1 C1R LTBP2	5.43e-05	225	33	6	MODULE_47
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	9.13e-06	3	52	2	C0265313
Disease	Weill-Marchesani Syndrome, Autosomal Dominant	FBN1 LTBP2	9.13e-06	3	52	2	C1869115
Disease	Weill-Marchesani Syndrome, Autosomal Recessive	FBN1 LTBP2	9.13e-06	3	52	2	C1869114
Disease	Weill-Marchesani syndrome	FBN1 LTBP2	1.82e-05	4	52	2	cv:C0265313
Disease	Weill-Marchesani syndrome (is_implicated_in)	FBN1 LTBP2	1.82e-05	4	52	2	DOID:0050475 (is_implicated_in)
Disease	Marfan syndrome (implicated_via_orthology)	FBN1 MATN3	1.36e-04	10	52	2	DOID:14323 (implicated_via_orthology)
Disease	Marfan Syndrome	FBN1 LTBP2	1.66e-04	11	52	2	C0024796
Disease	collagen disease (implicated_via_orthology)	COL4A1 COL4A3	1.99e-04	12	52	2	DOID:854 (implicated_via_orthology)
Disease	iron deficiency anemia (biomarker_via_orthology)	FN1 C1QA	2.35e-04	13	52	2	DOID:11758 (biomarker_via_orthology)
Disease	dilated cardiomyopathy (implicated_via_orthology)	DLL4 LTBP2 DLL1	3.85e-04	80	52	3	DOID:12930 (implicated_via_orthology)
Disease	Hyalinosis, Segmental Glomerular	COL4A1 FN1	1.12e-03	28	52	2	C0086432
Disease	cancer (implicated_via_orthology)	DLL4 DLL1 NOTCH2 AXIN2	1.28e-03	268	52	4	DOID:162 (implicated_via_orthology)
Disease	spontaneous coronary artery dissection	COL4A1 FBN1	1.37e-03	31	52	2	EFO_0010820
Disease	Squamous cell carcinoma	KLF5 CSNK2B NOTCH2	1.38e-03	124	52	3	C0007137
Disease	macrophage inflammatory protein 1a measurement	SCUBE1 CSNK2B	1.46e-03	32	52	2	EFO_0008218
Disease	Complement deficiency disease	C1QA C1R	1.55e-03	33	52	2	C0272242
Disease	Heart Failure, Diastolic	COL4A1 CDC25B	1.55e-03	33	52	2	C1135196
Disease	refractive error, self reported educational attainment	FBN1 LAMA2	1.65e-03	34	52	2	EFO_0004784, MONDO_0004892

Protein segments in the cluster

Peptide	Gene	Start	Entry
NHSGRFVCTVPGYYY	C1QA	146	P02745
SPFLECHGRGTCNYY	COL4A3	1611	Q01955
HCEPCTGYQYQVDRY	GRM4	541	Q14833
DQEDGYHCLCPPGYY	DLL4	341	Q9NR61
TQRVHCFCPGGSEYY	AXIN2	536	Q9Y2T1
HNYVGGYFCSCRPGY	C1R	166	P00736
APFIECHGRGTCNYY	COL4A1	1611	P02462
YFIAGCGPAVCYYAV	YWHAH-AS1	31	Q9Y442
NTHYCQCPLGYTGSY	NOTCH2	1131	Q04721
LPGSYGDLQCTQYCY	COLQ	431	Q9Y215
ASYHCDCYPGYTLNE	MATN3	411	O15232
LGCRGYYFVHELCAY	NTSR2	106	O95665
VIVDCRYPYEYEGGH	CDC25B	436	P30305
YEGQYCERCAPGYTG	LAMA2	1501	P24043
GYEAYECRGVCNYPL	BMP10	346	O95393
YIGGCCGFEPYHIRA	BHMT2	286	Q9H2M3
HPYLEPYGLVYCVNC	CHRDL1	51	Q9BU40
HRYVCECARGYGGPN	DLL1	501	O00548
GCYHNGVYYEPEQTV	FCGBP	1586	Q9Y6R7
HGVRYQCYCYGRGIG	FN1	581	P02751
GGYRCSCPQGYLQHY	FBN1	2586	P35555
FGRVLCTCYPGYRYD	CCBE1	106	Q6UXH8
YQQGDFGYCPRVYCE	CSNK2B	101	P67870
GNYSCPHYKGTIVVY	DTHD1	606	Q6ZMT9
VPGYVCLCNPGFHYD	LTBP2	1506	Q14767
IGGYYCSCRFGYILH	MASP1	161	P48740
YGGYRYSCCHPSCYG	KRTAP19-7	41	Q3SYF9
YPGVCSTTSYRTHCY	KRTAP24-1	11	Q3LI83
LSCYQVYCGRYINGH	HDAC6	1146	Q9UBN7
PGSFQCLCHRGYILY	SCUBE1	341	Q8IWY4
QITVYHYDGGPCYRC	MOCS3	211	O95396
YYPCPAVCTIYGDRH	OTOGL	941	Q3ZCN5
SSAYGLVHCCYEIYG	POLR1A	756	O95602
SVPGVYCLCVLYHGY	SH2D1A	36	O60880
VQYHGYCPDCDTRYN	PRR16	211	Q569H4
DCTYSIHVYPGYGIE	SEZ6L2	201	Q6UXD5
YGECLHSCPSGYYGH	RSPO2	71	Q6UXX9
YNVEGSFYCQCVPGY	ADGRE3	86	Q9BY15
SFYCQCVPGYRLHSG	ADGRE3	91	Q9BY15
YVKEHYPNGVCTVYG	CAPZA2	131	P47755
LPHSCGCYSDGKYYE	TECTA	1421	O75443
FGGYYCPCHGSHYDA	UQCRFS1	231	P47985
CYDNTREVPCYYGNT	ZP1	261	P60852
YHPQYGFYCAYGRPC	CD96	71	P40200
NCSRSYYYPVCGDGV	SLCO4C1	506	Q6ZQN7
GHYYCYAREGAARPA	USP35	861	Q9P2H5
YLQGRCPYGSRCHFI	ZFP36	151	P26651
VDYGLAYRYCPEGVH	VRK1	196	Q99986
NCYASYGLCGIHYID	GTF3C2	676	Q8WUA4
YCGPFEYEVGYCERL	PLBD2	141	Q8NHP8
RLCRQGYACPYYHNS	UNK	226	Q9C0B0
VFYKCGECGSYYNPH	ZNF619	186	Q8N2I2
HTGEKPYQCQYCEYR	ZFY	566	P08048
GIFPYQCEYCDYGAI	ZNF518B	186	Q9C0D4
RIHYCDYPGCTKVYT	KLF5	371	Q13887
KLYCGHCYYQTVVTP	LIMK1	131	P53667