Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

9.98e-11111586GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

5.50e-08141585GO:0003964
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

4.24e-07371586GO:0016891
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25

4.24e-07371586GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25

5.00e-07381586GO:0070001
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

5.35e-07211585GO:0035613
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

1.61e-06461586GO:0016893
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 PIWIL4 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

3.06e-06791587GO:0004521
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.18e-05381585GO:0034061
GeneOntologyMolecularFunctionformyltetrahydrofolate dehydrogenase activity

ALDH1L1 ALDH1L2

6.22e-0521582GO:0016155
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 PIWIL4 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

1.06e-041361587GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 PIWIL4 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

1.06e-041361587GO:0004519
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

TMEM94 ATP13A3 ATP1A1 ATP12A

1.82e-04361584GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

TMEM94 ATP13A3 ATP1A1 ATP12A

1.82e-04361584GO:0015662
GeneOntologyMolecularFunctionaldehyde dehydrogenase (NAD+) activity

ALDH1L1 ALDH1L2 ALDH3A1

2.06e-04151583GO:0004029
GeneOntologyMolecularFunctionaldehyde dehydrogenase [NAD(P)+] activity

ALDH1L1 ALDH1L2 ALDH3A1

3.05e-04171583GO:0004030
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH1 DNAH17

3.63e-04181583GO:0008569
GeneOntologyMolecularFunctionCoA carboxylase activity

ACACB PCCB

9.14e-0461582GO:0016421
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 PMS2P5 RTEL1 CECR2 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.17e-032621588GO:0140097
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1E TMEM94 HCN2 RYR3 ITPR3 SLC5A11 P2RX4 SLC28A2 KCNS2 ATP1A1 ATP12A

1.21e-0346515811GO:0046873
GeneOntologyMolecularFunctionligase activity, forming carbon-carbon bonds

ACACB PCCB

1.27e-0371582GO:0016885
GeneOntologyMolecularFunctionphosphofructokinase activity

PFKFB4 PFKL

1.27e-0371582GO:0008443
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 ERVK-7 FPGT ERVK-10 ERVK-8 ERVK-11

1.34e-031521586GO:0016779
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DNAH1 DNAH17

1.38e-03281583GO:0051959
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

TMEM94 ATP13A3 ATP1A1 ATP12A

1.47e-03621584GO:0019829
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA2 TMEM94 ATP13A3 ATP1A1 ATP12A

1.76e-031091585GO:0042626
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR3 ITPR3 P2RX4

1.86e-03311583GO:0099604
GeneOntologyMolecularFunctionO-acetyltransferase activity

LPCAT1 CASD1

2.16e-0391582GO:0016413
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

HCN2 RYR3 ITPR3

2.23e-03331583GO:0005217
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1E TMEM94 ANO10 HCN2 RYR3 ITPR3 SLC5A11 P2RX4 SLC28A2 KCNS2 ATP13A3 ATP1A1 ATP12A

2.43e-0366415813GO:0008324
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 PIWIL4 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

2.47e-032311587GO:0004518
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP12A

2.69e-03101582GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP12A

2.69e-03101582GO:0005391
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DNAH1 DNAH17

3.10e-03371583GO:0045505
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

2.90e-10131576GO:0015074
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 NYNRIN ERVK-8 ERVK-11

1.67e-06481576GO:0000731
GeneOntologyBiologicalProcessNADPH regeneration

ACACB ALDH1L1 MTOR ALDH1L2

3.61e-05251574GO:0006740
HumanPhenoAbsent sperm flagella

DNHD1 CFAP251 SPEF2 DNAH1 DNAH17

9.92e-0628555HP:0032558
HumanPhenoCoiled sperm flagella

DNHD1 CFAP251 SPEF2 DNAH1 DNAH17

1.97e-0532555HP:0032560
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

1.69e-06121464PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

1.69e-06121464IPR027970
DomainATPase_P-typ_cation-transptr_C

TMEM94 ATP13A3 ATP1A1 ATP12A

7.88e-06171464IPR006068
DomainCation_ATPase_C

TMEM94 ATP13A3 ATP1A1 ATP12A

7.88e-06171464PF00689
DomainL27_2

MPDZ PATJ

6.07e-0521462PF09045
Domain10_FTHF_DH

ALDH1L1 ALDH1L2

6.07e-0521462IPR011407
DomainL27_2

MPDZ PATJ

6.07e-0521462IPR015132
DomainC8

ZAN BMPER OTOG

9.78e-05121463PF08742
DomainTIL

ZAN BMPER OTOG

9.78e-05121463PF01826
DomainUnchr_dom_Cys-rich

ZAN BMPER OTOG

1.26e-04131463IPR014853
DomainC8

ZAN BMPER OTOG

1.26e-04131463SM00832
DomainTIL_dom

ZAN BMPER OTOG

1.60e-04141463IPR002919
Domain-

ALDH1L1 ALDH1L2

1.81e-04314623.10.25.10
DomainGART_AS

ALDH1L1 ALDH1L2

1.81e-0431462IPR001555
DomainFormyl_trans_C

ALDH1L1 ALDH1L2

1.81e-0431462PF02911
DomainFormyl_trans_C

ALDH1L1 ALDH1L2

1.81e-0431462IPR005793
DomainGART

ALDH1L1 ALDH1L2

1.81e-0431462PS00373
DomainATPase_P-typ_transduc_dom_A

TMEM94 ATP13A3 ATP1A1 ATP12A

1.94e-04371464IPR008250
DomainE1-E2_ATPase

TMEM94 ATP13A3 ATP1A1 ATP12A

1.94e-04371464PF00122
DomainVWF_type-D

ZAN BMPER OTOG

2.43e-04161463IPR001846
DomainVWFD

ZAN BMPER OTOG

2.43e-04161463PS51233
DomainATPase_P-typ_TM_dom

TMEM94 ATP1A1 ATP12A

2.43e-04161463IPR023298
DomainVWD

ZAN BMPER OTOG

2.43e-04161463SM00216
Domain-

TMEM94 ATP1A1 ATP12A

2.43e-041614631.20.1110.10
DomainAld_DH_CS_GLU

ALDH1L1 ALDH1L2 ALDH3A1

2.43e-04161463IPR029510
DomainVWD

ZAN BMPER OTOG

2.43e-04161463PF00094
DomainAld_DH_CS_CYS

ALDH1L1 ALDH1L2 ALDH3A1

2.94e-04171463IPR016160
DomainVWF_dom

ZAN NELL2 BMPER OTOG

3.18e-04421464IPR001007
DomainCation_ATPase_N

ATP13A3 ATP1A1 ATP12A

3.50e-04181463PF00690
DomainALDEHYDE_DEHYDR_CYS

ALDH1L1 ALDH1L2 ALDH3A1

3.50e-04181463PS00070
DomainALDEHYDE_DEHYDR_GLU

ALDH1L1 ALDH1L2 ALDH3A1

3.50e-04181463PS00687
DomainG8_domain

PKHD1L1 PKHD1

3.60e-0441462IPR019316
DomainG8

PKHD1L1 PKHD1

3.60e-0441462PS51484
DomainCarboxyl_trans

ACACB PCCB

3.60e-0441462PF01039
Domain-

ALDH1L1 ALDH1L2

3.60e-04414623.40.50.170
DomainFormyl_transf_N

ALDH1L1 ALDH1L2

3.60e-0441462IPR002376
DomainCOA_CT_CTER

ACACB PCCB

3.60e-0441462PS50989
DomainCOA_CT_NTER

ACACB PCCB

3.60e-0441462PS50980
DomainG8

PKHD1L1 PKHD1

3.60e-0441462SM01225
DomainG8

PKHD1L1 PKHD1

3.60e-0441462PF10162
DomainCOA_CT_N

ACACB PCCB

3.60e-0441462IPR011762
DomainCOA_CT_C

ACACB PCCB

3.60e-0441462IPR011763
DomainFormyl_trans_N

ALDH1L1 ALDH1L2

3.60e-0441462PF00551
DomainCarboxyl_trans

ACACB PCCB

3.60e-0441462IPR000022
Domain-

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-041914633.40.605.10
DomainAldedh

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-04191463PF00171
DomainVWC_out

ZAN NELL2 OTOG

4.14e-04191463SM00215
DomainAld_DH_C

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-04191463IPR016163
DomainAld_DH_N

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-04191463IPR016162
DomainAld_DH/histidinol_DH

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-04191463IPR016161
DomainATPase_P-typ_cation-transptr_N

ATP13A3 ATP1A1 ATP12A

4.14e-04191463IPR004014
DomainAldehyde_DH_dom

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-04191463IPR015590
Domain-

ALDH1L1 ALDH1L2 ALDH3A1

4.14e-041914633.40.309.10
Domain-

ALDH1L1 ALDH1L2

5.98e-04514621.10.1200.10
DomainPHOSPHOPANTETHEINE

ALDH1L1 ALDH1L2

5.98e-0451462PS00012
DomainFormyl_transferase_C-like

ALDH1L1 ALDH1L2

5.98e-0451462IPR011034
DomainINTEGRASE

ERVK-6 NYNRIN

5.98e-0451462PS50994
DomainIntegrase_cat-core

ERVK-6 NYNRIN

5.98e-0451462IPR001584
DomainNlgn

NLGN1 NLGN4X

5.98e-0451462IPR000460
DomainPP-binding

ALDH1L1 ALDH1L2

5.98e-0451462PF00550
DomainACP_DOMAIN

ALDH1L1 ALDH1L2

5.98e-0451462PS50075
DomainRIH_assoc-dom

RYR3 ITPR3

8.92e-0461462IPR013662
DomainPbH1

PKHD1L1 PKHD1

8.92e-0461462SM00710
DomainIns145_P3_rec

RYR3 ITPR3

8.92e-0461462PF08709
DomainRIH_assoc

RYR3 ITPR3

8.92e-0461462PF08454
DomainRIH_dom

RYR3 ITPR3

8.92e-0461462IPR000699
DomainIns145_P3_rcpt

RYR3 ITPR3

8.92e-0461462IPR014821
DomainRyanodine_recept-rel

RYR3 ITPR3

8.92e-0461462IPR015925
DomainFAT

TRRAP MTOR

8.92e-0461462PS51189
DomainFATC

TRRAP MTOR

8.92e-0461462PS51190
Domain-

RYR3 ITPR3

8.92e-04614621.25.10.30
DomainFAT

TRRAP MTOR

8.92e-0461462PF02259
DomainPIK-rel_kinase_FAT

TRRAP MTOR

8.92e-0461462IPR003151
DomainFATC_dom

TRRAP MTOR

8.92e-0461462IPR003152
DomainRYDR_ITPR

RYR3 ITPR3

8.92e-0461462PF01365
DomainPbH1

PKHD1L1 PKHD1

8.92e-0461462IPR006626
DomainP-type_ATPase_IIC

ATP1A1 ATP12A

8.92e-0461462IPR005775
DomainPIK_FAT

TRRAP MTOR

8.92e-0461462IPR014009
DomainPP-bd_ACP

ALDH1L1 ALDH1L2

8.92e-0461462IPR009081
DomainFATC

TRRAP MTOR

8.92e-0461462SM01343
DomainIntegrin_dom

ITGAE ITGAX ITGB5

9.49e-04251463IPR032695
DomainVWF_A

ITGAE ITGAX ITGB5 SEC24D HMCN2

1.08e-03991465IPR002035
DomainPectin_lyase_fold/virulence

PKHD1L1 PKHD1

1.65e-0381462IPR011050
Domain-

ATP13A3 ATP1A1 ATP12A

1.97e-033214633.40.1110.10
Domain-

ATP13A3 ATP1A1 ATP12A

1.97e-033214632.70.150.10
DomainIon_trans_dom

CACNA1E HCN2 RYR3 ITPR3 KCNS2

2.02e-031141465IPR005821
DomainIon_trans

CACNA1E HCN2 RYR3 ITPR3 KCNS2

2.02e-031141465PF00520
DomainATPase_P-typ_cyto_domN

ATP13A3 ATP1A1 ATP12A

2.55e-03351463IPR023299
DomainMIR

RYR3 ITPR3

2.62e-03101462PF02815
DomainMIR_motif

RYR3 ITPR3

2.62e-03101462IPR016093
DomainMIR

RYR3 ITPR3

2.62e-03101462PS50919
DomainMIR

RYR3 ITPR3

2.62e-03101462SM00472
DomainVWFC_1

ZAN NELL2 BMPER

2.77e-03361463PS01208
DomainATPase_P-typ_P_site

ATP13A3 ATP1A1 ATP12A

2.77e-03361463IPR018303
DomainP_typ_ATPase

ATP13A3 ATP1A1 ATP12A

2.77e-03361463IPR001757
DomainATPASE_E1_E2

ATP13A3 ATP1A1 ATP12A

2.77e-03361463PS00154
DomainIntegrin_alpha

ITGAE ITGAX

3.19e-03111462PF00357
DomainVWFC_2

ZAN NELL2 BMPER

3.23e-03381463PS50184
DomainVWC

ZAN NELL2 BMPER

3.23e-03381463SM00214
DomainOlfact_rcpt

OR4D6 OR6C65 OR11H12 OR4D2 OR4C15 OR11H1 OR6C4 OR6C75 OR6K3

3.80e-033931469IPR000725
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

6.42e-096160420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

6.42e-096160425930072
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25 ERVK-11

2.80e-0794160721542922
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PMS2P2 INTU RASA1 RTEL1 PFKFB4 PFKL CERT1 TRRAP ITGB5 TASOR2 DNAH1 TYK2 SCARB1 LMLN CSTF3 RIPOR1 LRRC7 LIMCH1 PATJ GPT2 LSM7 VPS13B ADGRD1

3.72e-0714891602328611215
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

3.81e-074160310469592
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-18

9.49e-075160312629516
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-10 ERVK-18 ERVK-25 ERVK-11

1.26e-0618160418664271
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ACACB TOPAZ1 ALDH1L1 ME1 TRRAP SPATA31A6 TGM5 RYR3 LIMCH1 ATP1A1 HERC1 DNPEP

3.62e-064971601236774506
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCA2 TMEM94 FBXL12 NUBPL TRRAP FAAP100 ITGB5 MAP3K5 ITPR3 TYK2 CNPPD1 MTOR SCARB1 A4GALT RIPOR1 GPC2 HERC1 MVB12B

3.71e-0611051601835748872
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5

4.27e-0624160432212159
Pubmed

Genetic control of leucocyte--endothelial cell interaction in collagen-induced arthritis.

SELL IL13RA1 IL1B

1.12e-0510160320223839
Pubmed

RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non-Small Cell Lung Carcinomas Sensitive to MEK Inhibition.

RASA1 NF1

2.10e-052160229127119
Pubmed

Tumor-secreted factors induce IL-1β maturation via the glucose-mediated synergistic axis of mTOR and NF-κB pathways in mouse macrophages.

MTOR IL1B

2.10e-052160230586442
Pubmed

The murine vik gene (chromosome 9) encodes a putative receptor with unique protein kinase motifs.

ME1 RYK

2.10e-05216028380921
Pubmed

SF3B3-regulated mTOR alternative splicing promotes colorectal cancer progression and metastasis.

SF3B3 MTOR

2.10e-052160238671459
Pubmed

Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation.

P2RX4 MTOR

2.10e-052160236385525
Pubmed

Relocation of phosphofructokinases within epithelial cells is a novel event preceding breast cancer recurrence that accurately predicts patient outcomes.

PFKFB4 PFKL

2.10e-052160234348486
Pubmed

PATJ and MPDZ are required for trophectoderm lineage specification in early mouse embryos.

MPDZ PATJ

2.10e-052160237318097
Pubmed

A Significant Difference in Core PDZ Interactivity of SARS-CoV, SARS-CoV2 and MERS-CoV Protein E Peptide PDZ Motifs In Vitro.

MPDZ PATJ

2.10e-052160236932261
Pubmed

Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.

RASA1 NF1

2.10e-052160212730209
Pubmed

Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.

NF1 MTOR

2.10e-052160221748792
Pubmed

[Presence of a male sterility factor, Hst-2, segregating in interspecies crosses. M. musculus L. x M. spretus Lastaste and linked to Mod-1, and Mpi-1 on chromosome 9].

ME1 MPI

2.10e-05216026812867
Pubmed

Characterization of the cytoplasmic domain of interleukin-13 receptor-alpha.

IL13RA1 TYK2

2.10e-052160210409622
Pubmed

ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.

ALDH1L1 ALDH1L2

2.10e-052160220498374
Pubmed

CD11c(+)  CD103(+) cells of Mycobacterium tuberculosis-infected C57BL/6 but not of BALB/c mice induce a high frequency of interferon-γ- or interleukin-17-producing CD4(+) cells.

ITGAE ITGAX

2.10e-052160225322675
Pubmed

CD103 Regulates Dermal Regulatory T Cell Motility and Interactions with CD11c-Expressing Leukocytes to Control Skin Inflammation.

ITGAE ITGAX

2.10e-052160237341508
Pubmed

Treponemapallidum Dysregulates Monocytes and Promotes the Expression of IL-1β and Migration in Monocytes Through the mTOR Signaling Pathway.

MTOR IL1B

2.10e-052160233282751
Pubmed

Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

ERVK-6 ERVK-18

2.10e-052160211672541
Pubmed

Tbx6 controls left-right asymmetry through regulation of Gdf1.

DAND5 RFX3 WNT5B

2.64e-0513160329650695
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

MBTD1 TMEM94 FBXL12 FAM91A1 ANO10 ERVK-10 FAAP100 RYK TASOR2 FREM2 NF1 NLGN4X ARSL RIPOR1 ERVK-25 ZBTB18 DNPEP

4.83e-0512151601715146197
Pubmed

Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase.

ALDH1L1 ALDH1L2

6.29e-053160219933275
Pubmed

Linkage of the structural gene for uroporphyrinogen I synthase to markers on mouse chromosome 9 in a cross between feral and inbred mice.

ME1 MPI

6.29e-05316027138495
Pubmed

Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.

RASA1 NF1

6.29e-053160226002977
Pubmed

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein.

RASA1 NF1

6.29e-05316027477259
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-11

6.29e-05316029971820
Pubmed

The genes coding for pyruvate kinase (M2) and mannosephosphate isomerase are linked in man and mouse.

ME1 MPI

6.29e-0531602752545
Pubmed

[Genetic studies of primary open-angle glaucoma].

WDR36 MYOC

6.29e-053160225711070
Pubmed

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells.

MPDZ PATJ

6.29e-053160212403818
Pubmed

Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.

ITGB5 IL1B

6.29e-053160218276918
Pubmed

Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase.

ALDH1L1 ALDH1L2

6.29e-053160221238436
Pubmed

[Genetic variants of CYP1B1 and WDR36 in the patients with primary congenital glaucoma and primary open angle glaucoma from Saint-Petersburg].

WDR36 MYOC

6.29e-053160220198978
Pubmed

A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer.

RASA1 NF1

6.29e-053160228108518
Pubmed

Elucidating the mechanism of IL-1β-Mediated Piezo1 expression regulation of chondrocyte autophagy and apoptosis via the PI3K/AKT/mTOR signaling Pathway.

MTOR IL1B

6.29e-053160238134572
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-18

6.29e-053160210516026
Pubmed

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.

MAP3K5 MTOR

6.29e-053160215218033
Pubmed

Application of the ovarian teratoma mapping method in the mouse.

ME1 MPI

6.29e-05316026852526
Pubmed

Similar and distinct properties of MUPP1 and Patj, two homologous PDZ domain-containing tight-junction proteins.

MPDZ PATJ

6.29e-053160219255144
Pubmed

The serotonin 5-HT1B receptor subtype (Htr1b) gene maps to mouse chromosome 9.

ME1 MPI

6.29e-05316028358175
Pubmed

Tg (9 HSA-MYC), a homozygous lethal insertion in the mouse.

ME1 MPI

6.29e-05316021797233
Pubmed

Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway.

MTOR IL1B

6.29e-053160227669541
Pubmed

Esterase-17 (ES-17): characterization and genetic location on chromosome 9 of a bis-p-nitrophenyl phosphate-resistant esterase of the house mouse (Mus musculus).

ME1 MPI

6.29e-05316026838491
Pubmed

Effects of timolol on MYOC, OPTN, and WDR36 RNA levels.

WDR36 MYOC

6.29e-053160218195223
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TMEM94 NUBPL NF1 NLGN4X MTOR SCARB1 EHD1 ATP13A3 ATP1A1 PATJ VPS13B

7.06e-055691601130639242
Pubmed

An investigation into the human serum "interactome".

SPEF2 SPATA31A7 ERVK-10 ITGB5 AP4E1 SACS

1.09e-04162160615174051
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

INTU TMEM94 FAM91A1 NLGN1 CSMD3 RIPOR1 LRRC7 LIMCH1 VPS13B

1.20e-04407160912693553
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR3 ITPR3

1.25e-044160222100703
Pubmed

Multiple gene polymorphisms analysis revealed a different profile of genetic polymorphisms of primary open-angle glaucoma in northern Chinese.

WDR36 MYOC

1.25e-044160219145250
Pubmed

MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1.

NF1 MTOR

1.25e-044160224509877
Pubmed

Glaucomatous MYOC mutations activate the IL-1/NF-κB inflammatory stress response and the glaucoma marker SELE in trabecular meshwork cells.

MYOC IL1B

1.25e-044160226396484
Pubmed

Neurofibromatosis 1 (NF1) heterozygosity results in a cell-autonomous growth advantage for astrocytes.

RASA1 NF1

1.25e-044160211246230
Pubmed

Localization of cytochrome P1-450 and P3-450 genes to mouse chromosome 9.

ME1 MPI

1.25e-04416026328503
Pubmed

p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.

NF1 MTOR

1.25e-044160229392777
Pubmed

Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia.

CHGA IL1B

1.25e-044160223831373
Pubmed

Location of the gene for theta antigen in the mouse. III. The position of Thy-1 relative to Lap-1 and Mpi-1.

ME1 MPI

1.25e-0441602314952
Pubmed

Polymorphism and linkage for mannosephosphate isomerase in Mus musculus.

ME1 MPI

1.25e-04416024693062
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN1 NLGN4X

1.25e-044160216077734
Pubmed

Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex.

MTOR IL1B

1.25e-044160225418470
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10

1.25e-04416027983737
Pubmed

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing.

PIWIL4 TASOR2

1.25e-044160232719317
Pubmed

[Modification of Levels of Adhesion Molecule Expression of Human Innate Immune Cells by Glycopolymers of Marine Bacteria].

SELL ITGAX

1.25e-044160226852488
Pubmed

Aldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systems.

ALDH1L1 ALDH1L2 ALDH3A1

1.58e-0423160318971422
Pubmed

Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia.

OR6C65 OR6C4 OR6C75

1.80e-0424160324152035
Pubmed

The DNA sequence, annotation and analysis of human chromosome 3.

ZNF717 NLGN1 ATP13A3 ERVK-11

1.96e-0462160416641997
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP12A

2.08e-04516023035563
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

2.08e-045160211401426
Pubmed

Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.

NLGN1 NLGN4X

2.08e-045160215620359
Pubmed

A serum protein polymorphism determinant on chromosome 9 of Mus musculus.

ME1 MPI

2.08e-04516026929943
Pubmed

A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis.

SELL ITGAE

2.08e-045160218250468
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN1 NLGN4X

2.08e-045160237865312
Pubmed

Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance.

ITGAE ITGAX

2.08e-045160223733880
Pubmed

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.

PKHD1L1 PKHD1

2.08e-045160220048263
Pubmed

Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins.

SELL ITGB5

2.08e-045160214718670
Pubmed

Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.

KNTC1 NBAS

2.08e-045160220462495
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN1 NLGN4X

2.08e-045160210996085
Pubmed

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

ATP1A1 ATP12A

2.08e-045160216870707
Pubmed

Digitoxin Suppresses Human Cytomegalovirus Replication via Na+, K+/ATPase α1 Subunit-Dependent AMP-Activated Protein Kinase and Autophagy Activation.

MTOR ATP1A1

2.08e-045160229321306
Pubmed

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.

ADRM1 ITPR3 HERC1 LSM7

2.35e-0465160428276505
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGAE ITGAX ITGB5

2.58e-0427160331541017
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN1 NLGN4X

3.12e-046160221838267
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP12A

3.12e-04616023036582
Pubmed

Transcription factor AP-2β regulates the neurotransmitter phenotype and maturation of chromaffin cells.

DBH CHGA

3.12e-046160220875861
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR3 ITPR3

3.12e-046160223463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR3 ITPR3

3.12e-046160225966694
Pubmed

The isolation and mapping of PCR markers specific to mouse Chromosome 2.

DBH IL1B

3.12e-04616028835533
Pubmed

Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.

MPDZ PATJ

3.12e-046160217397395
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN1 NLGN4X

3.12e-046160229724786
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR3 ITPR3

3.12e-046160220519450
Pubmed

Multiple CD11c+ cells collaboratively express IL-1β to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth.

ITGAX IL1B

3.12e-046160224659690
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR3 ITPR3

3.12e-046160216844763
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CACNA1E NLGN1 NF1 NLGN4X SACS MTOR LRRC7

3.40e-04281160728706196
Cytoband5q13.3

RASA1 CERT1 PDE8B

2.51e-043516035q13.3
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

3.33e-0481602chr9q12
GeneFamilyAldehyde dehydrogenases

ALDH1L1 ALDH1L2 ALDH3A1

1.20e-0419933398
GeneFamilyOlfactory receptors, family 6

OR6C65 OR6C4 OR6C75 OR6K3

1.36e-0451934153
GeneFamilyPDZ domain containing|Crumbs complex

MPDZ PATJ

9.20e-0499321223
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELL MASP1 CSMD3

3.15e-03579331179
GeneFamilyDyneins, axonemal

DNAH1 DNAH17

3.39e-0317932536
GeneFamilyAminopeptidases|CD molecules

LAP3 DNPEP

3.39e-0317932104
GeneFamilySulfatases

ARSL GNS

3.80e-0318932410
GeneFamilyCD molecules|Integrin alpha subunits

ITGAE ITGAX

3.80e-03189321160
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN NLGN1 CSMD3 PKHD1L1 RYR3 DNAH1 PKHD1 ATP12A

1.24e-07169152812bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN CSMD3 PKHD1L1 RYR3 DNAH1 FREM2 PKHD1 OTOG

2.38e-0718415282cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN CSMD3 PKHD1L1 RYR3 DNAH1 FREM2 PKHD1 OTOG

2.38e-071841528ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN CSMD3 PKHD1L1 RYR3 DNAH1 FREM2 PKHD1 OTOG

2.38e-0718415282b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LPCAT1 CECR2 NLGN1 ME1 MAP3K5 PKHD1 LIMCH1 PATJ

2.70e-07187152858d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZAN CSMD3 PKHD1L1 FREM2 PKHD1 LRRC7 ATP12A

1.44e-061621527bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL13RA1 INTU MPDZ CERT1 AP4E1 LIMCH1 GPC2

1.50e-061631527132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 MAP3K5 PKHD1 LIMCH1 PATJ

2.59e-0617715279af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TNPO2 TAB3 DNAH1 RIPOR1 LIMCH1 GPT2 ZBTB18

2.90e-06180152762511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TNPO2 TAB3 DNAH1 RIPOR1 LIMCH1 GPT2 ZBTB18

3.12e-06182152703992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LPCAT1 CECR2 NLGN1 FREM2 NELL2 LIMCH1 PATJ

3.47e-0618515270d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCelldroplet-Thymus-nan-24m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E IL13RA1 CPED1 SEC24D ALDH1L2 A4GALT HCRTR2

3.47e-061851527e583f6601f9ed79b0b23d2f9426a4ba8b969230b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 ITPR3 FREM2 PKHD1 LIMCH1 ATP1A1 PATJ

3.73e-0618715275df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellCOPD-Myeloid-cMonocyte|Myeloid / Disease state, Lineage and Cell class

SELL LPCAT1 ITGAX SRGAP1 EHD1 ATP13A3 IL1B

4.00e-0618915276294691231c7d38707323cf31578a107d3b2c622
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 ITPR3 FREM2 PKHD1 LIMCH1 ATP1A1 PATJ

4.28e-061911527ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 ITPR3 FREM2 PKHD1 LIMCH1 ATP1A1 PATJ

4.43e-06192152729f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages|GI_small-bowel / Manually curated celltypes from each tissue

IL13RA1 HLA-DMA CPED1 ITGB5 CD163L1 SRGAP1 IL1B

5.61e-06199152796070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCell390C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MASP1 PFKFB4 DNAH1 FANCB LMLN LIMCH1

1.39e-051521526ebce79e106bf1d84241f8dd3496ff1771f9666be
ToppCell390C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MASP1 PFKFB4 DNAH1 FANCB LMLN LIMCH1

1.39e-0515215264a749d1b6d35fd55a8c42d7bd04b6ff5b11ce781
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

ACACB MYOC CPED1 RYR3 HMCN2 ADGRD1

1.86e-0516015268a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

ACACB MYOC CPED1 RYR3 HMCN2 ADGRD1

1.86e-051601526d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

ACACB MYOC CPED1 RYR3 HMCN2 ADGRD1

1.86e-051601526c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|390C / Donor, Lineage, Cell class and subclass (all cells)

RASA1 ITGAX P2RX4 NYNRIN LRRC7 GPC2

2.62e-051701526439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMA CHGA ITGAX ITGB5 P2RX4 GNS

2.62e-051701526067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELL THEMIS ITGAE CD163L1 SLC28A2 PKHD1

2.71e-051711526801893c318f7b1abc8d97bac86a00974f910a71c
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E NLGN1 ALDH1L1 SLC5A11 FREM2 PKHD1

3.39e-05178152623a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 PKHD1 LIMCH1 PATJ

3.50e-05179152604ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

INTU ITGAX ITGB5 CD163L1 SRGAP1 IL1B

3.61e-0518015267be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 PKHD1 LIMCH1 PATJ

3.72e-051811526b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E NLGN1 SLC5A11 FREM2 PKHD1 GPT2

3.72e-0518115266980ea624151da32b7f537f263e40fcb87a02e81
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 PKHD1 LIMCH1 PATJ

4.08e-05184152642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellControl-Epithelial_alveolar-AT_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LPCAT1 CECR2 NLGN1 FREM2 NELL2 PATJ

4.08e-05184152651e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell(7)_DC_activated|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

IL13RA1 WNT5B NELL2 PDE8B SRGAP1 LIMCH1

4.08e-051841526b89871a3e36fde6daa68daf116f8c8d587554c0f
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 PKHD1 LIMCH1 PATJ

4.20e-0518515263937e026add96a396122139daf8011cfbc60e75c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 PKHD1 LIMCH1 PATJ

4.33e-0518615264e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CECR2 NLGN1 ME1 PKHD1 LIMCH1 PATJ

4.33e-0518615263aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-DZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFAP251 HLA-DMA ITGAE PKHD1L1 A4GALT LSM7

4.60e-0518815269a10536afa2dea34c78421d36564cfd8252afe45
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

GCGR ALDH1L1 FREM2 PKHD1 ATP1A1 PATJ

4.60e-0518815261d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

4.87e-0519015264b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

CFAP251 HLA-DMA ITGAE PDE8B SCARB1 A4GALT

4.87e-051901526c5c80a6b9087821a2e07250fa90bcd3505f103b6
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NLGN1 WNT5B SEC24D HMCN2 ALDH1L2 LRRC7

5.17e-0519215268d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

LPCAT1 CECR2 ITPR3 FREM2 LIMCH1 PATJ

5.17e-05192152658c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 ITPR3 FREM2 PKHD1 LIMCH1 PATJ

5.17e-051921526fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

5.17e-0519215268e606eae3e5b07a856d3c2a74186d486da96309c
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LPCAT1 ITPR3 FREM2 PKHD1 LIMCH1 PATJ

5.32e-051931526a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INTU CFAP251 SPEF2 EFHB C11orf16 RFX3

5.47e-0519415264a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCelldroplet-Lung-1m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PFKFB4 TMBIM6 ITGAX ATP13A3 PATJ GNS

5.47e-051941526d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCell(010)_cDC|World / immune cells in Peripheral Blood (logTPM normalization)

IL13RA1 HLA-DMA CPED1 ITGAX ITGB5 LIMCH1

5.63e-0519515264aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCellILEUM-non-inflamed-(3)_moDC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IL13RA1 HLA-DMA ITGAX CD163L1 SRGAP1 IL1B

5.79e-051961526e10f01172fd076d6892906853f9375d4c3058951
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 SPEF2 ALDH1L1 EFHB C11orf16 RFX3

5.96e-05197152691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell(6)_Macrophage|World / shred on Cell_type and subtype

IL13RA1 ITGAX ITGB5 NELL2 CD163L1 IL1B

5.96e-051971526010b275d4da4a896175ad7fbaa96d1dc11a0b744
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 SPEF2 ALDH1L1 EFHB C11orf16 RFX3

5.96e-05197152622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INTU CFAP251 SPEF2 MPDZ RFX3 LMLN

5.96e-05197152674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 SPEF2 ALDH1L1 EFHB C11orf16 RFX3

5.96e-0519715263bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellPBMC-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

5.96e-05197152622e4ffb5de483eaf78f14badf3d08db898e3b3dd
ToppCellPBMC-Severe-Myeloid-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

5.96e-051971526346974c6c5809a3fe88cbf067e2d64c340310a31
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP251 SPEF2 ALDH1L1 EFHB C11orf16 RFX3

5.96e-05197152687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellPBMC-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

5.96e-0519715261ae45c1ec3b3f88e0c1f99de58c58b1ec1b968ee
ToppCellCOVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease group, lineage and cell class

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

5.96e-051971526843b0f1cc26864ee635df7938c77552ee06fe00b
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPCAT1 CECR2 ITPR3 FREM2 LIMCH1 ADGRD1

5.96e-051971526bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellPBMC-Severe-Myeloid-cDC-cDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

5.96e-051971526f78f44dcd7855c96f148678c1f416075aef71b4e
ToppCellcontrol-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 HLA-DMA CPED1 ITGAX LIMCH1 IL1B

6.30e-05199152631825ba336603fe940dea6022e18ec25af110f4c
ToppCell3'_v3-GI_small-bowel-Myeloid_Mac|GI_small-bowel / Manually curated celltypes from each tissue

IL13RA1 HLA-DMA CPED1 ITGB5 CD163L1 IL1B

6.30e-0519915268990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCellSigmoid-T_cell-Tcm|T_cell / Region, Cell class and subclass

SELL IL13RA1 SF3B3 MTOR PDE8B OR6C75

6.30e-051991526acdf95f4d58df47690f4ae254245bc618f9ac07e
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

IL13RA1 PFKFB4 ME1 ITGB5 IL1B GNS

6.30e-051991526facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

IL13RA1 PFKFB4 ME1 ITGB5 IL1B GNS

6.30e-051991526dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LPCAT1 ITPR3 FREM2 LIMCH1 ATP1A1 ADGRD1

6.30e-0519915262dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

WDR36 MAP3K5 SRGAP1 ATP13A3 LIMCH1 ADGRD1

6.30e-0519915268b86c69aaf60feff53aa782559cfece7342a23de
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E NELL2 SRGAP1 LIMCH1 ZBTB18 RAI2

6.48e-05200152684e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellmild-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

6.48e-05200152686f585bf9066b179bbcbc703bf43f15da4a07284
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Monocytic-Monocyte_CD14|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SELL ITGAX DNAH17 EHD1 ATP13A3 IL1B

6.48e-05200152654221271becd02a4ffa826e06c8e76fcd2651d50
ToppCellSigmoid-Macrophage-Macrophage|Sigmoid / Region, Cell class and subclass

IL13RA1 ITGAX ITGB5 CD163L1 SRGAP1 IL1B

6.48e-0520015269ee3a799de7bade1bfe94b6827461633f02bc1dc
ToppCellSigmoid-(5)_Dendritic_cell-(51)_cDC1|Sigmoid / shred on region, Cell_type, and subtype

CECR2 NUBPL TGM5 PDE8B LIMCH1 MVB12B

6.48e-0520015264ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

LPCAT1 CECR2 ME1 PKHD1 LIMCH1 PATJ

6.48e-0520015262dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

ALDH1L1 WNT5B ALDH1L2 SRGAP1 ATP12A GPT2

6.48e-052001526682960e28542a3d6c119047cd0131941932cfdea
ToppCellCOVID-19-COVID-19_Severe-Myeloid-cDC|COVID-19_Severe / Disease, condition lineage and cell class

IL13RA1 HLA-DMA CPED1 ITGAX LAP3 LIMCH1

6.48e-052001526e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1E ALDH1L1 ALDH1L2 SRGAP1 ATP12A GPT2

6.48e-052001526ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

CHGA NELL2 SRGAP1 LRRC7 GPC2 ZBTB18

6.48e-052001526af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellSigmoid-Macrophage|Sigmoid / Region, Cell class and subclass

IL13RA1 ITGAX ITGB5 CD163L1 SRGAP1 IL1B

6.48e-052001526b07ac0ff3b8530e99094678fed80f35949cafac8
ToppCellSigmoid-(6)_Macrophage-(60)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

IL13RA1 ITGAX ITGB5 CD163L1 SRGAP1 IL1B

6.48e-052001526ad84a83a5a1893f7b053d39eddeca851463a8ff0
ToppCellSigmoid-Dendritic_cell-cDC1|Sigmoid / Region, Cell class and subclass

CECR2 NUBPL TGM5 PDE8B LIMCH1 MVB12B

6.48e-0520015263523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E NELL2 SRGAP1 LIMCH1 ZBTB18 RAI2

6.48e-05200152619055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 HLA-DMA CPED1 ITGAX LIMCH1 IL1B

6.48e-0520015264a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellSigmoid-Dendritic_cell-cDC1|Dendritic_cell / Region, Cell class and subclass

NUBPL TGM5 PDE8B LIMCH1 GPT2 MVB12B

6.48e-05200152609deb831fc2c8a8867cc850f3aa094a5e48489ff
ToppCellSigmoid-(6)_Macrophage|Sigmoid / shred on region, Cell_type, and subtype

IL13RA1 ITGAX ITGB5 CD163L1 SRGAP1 IL1B

6.48e-0520015269e10cca4429de2c4c8c3c6cf2c9e28637a095be9
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1E ALDH1L1 ALDH1L2 SRGAP1 ATP12A GPT2

6.48e-05200152685c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell(60)_Macrophage|World / shred on Cell_type and subtype

IL13RA1 ITGAX ITGB5 NELL2 CD163L1 IL1B

7.22e-05204152606d0cb306f1ad0014d81f8228868938e48c2bcf3
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MASP1 ABCA2 RYR3 WDR91 HMCN2

7.80e-0512815252cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

TOPAZ1 NOX3 CSMD3 SPATA31A6 PKHD1

8.40e-0513015251ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-RGCs_3|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

INTU PFKFB4 ARSL SLC28A2 LIMCH1

1.04e-0413615255e209185b5f6e9347829fc9066f0b2c3711df057
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

MYOC NLGN1 DNAH1 CD163L1 RAI2

1.08e-041371525b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND01-03-samps / Age Group, Lineage, Cell class and subclass

NLGN1 DNAH1 HMCN2 TESK2 ADGRD1

1.08e-041371525a69976938d4e89315ec0be3a332b91ddf3799d65
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RASA1 FBXL12 PATJ

1.16e-04281523456cf2e0a6ea59c279efc77a1d02e5572196cb6b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL13RA1 ITGB5 SLC5A11 HMCN2 SRGAP1

1.19e-0414015252c44e8cc5190226049be7ebc465d685393e701c4
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2|TCGA-Bladder / Sample_Type by Project: Shred V9

MYOC CPED1 RYR3 HMCN2 ADGRD1

1.23e-0414115251baa054c2ae3b446d1954244b7fbf8af824ef345
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GCGR WNT5B FREM2 NYNRIN ADGRD1

1.31e-04143152527e06327f96cb72bd111ea6ece6307e5ebb3a146
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GCGR WNT5B FREM2 NYNRIN ADGRD1

1.31e-0414315254edef95ae2a1ef4fc4b0d4fadf75bfc54b583932
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELL THEMIS ITGAE CD163L1 SLC28A2

1.40e-041451525a9f5a32abcf3eb2c66bd65f2521a6dd4ce56c635
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSMD3 FREM2 PKHD1 LRRC7 ATP12A

1.40e-04145152596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SELL THEMIS ITGAE CD163L1 SLC28A2

1.59e-0414915254fda987bc7bb6d1dbd41b8f1f8c1bc59613255a8
ComputationalGenes in the cancer module 412.

ITGAE ITGAX ITGB5

1.16e-0413823MODULE_412
DiseasePheochromocytoma, Extra-Adrenal

DBH CHGA NF1

5.60e-05161403C1257877
DiseaseIntellectual Disability

CACNA1E TMEM94 CERT1 TRRAP AP4E1 NF1 SACS MTOR ATP1A1 GPT2

5.73e-0544714010C3714756
DiseasePheochromocytoma

DBH CHGA NF1

9.58e-05191403C0031511
Diseasecrescentic glomerulonephritis (implicated_via_orthology)

MTOR IL1B

3.31e-0461402DOID:13139 (implicated_via_orthology)
DiseaseGlaucoma

WDR36 MYOC

3.31e-0461402cv:C0017601
DiseaseX-13553 measurement

DBH ARSL

3.31e-0461402EFO_0021355
DiseaseSarcomatoid Renal Cell Carcinoma

DNHD1 FPGT CSMD3 MTOR SCARB1

3.71e-041281405C1266043
DiseaseChromophobe Renal Cell Carcinoma

DNHD1 FPGT CSMD3 MTOR SCARB1

3.71e-041281405C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

DNHD1 FPGT CSMD3 MTOR SCARB1

3.71e-041281405C1266044
DiseasePapillary Renal Cell Carcinoma

DNHD1 FPGT CSMD3 MTOR SCARB1

3.71e-041281405C1306837
DiseaseRenal Cell Carcinoma

DNHD1 FPGT CSMD3 MTOR SCARB1

3.71e-041281405C0007134
DiseaseIgA glomerulonephritis (is_implicated_in)

SELL CHGA IL1B

3.86e-04301403DOID:2986 (is_implicated_in)
DiseaseOvarian Mucinous Adenocarcinoma

TRRAP RYK MTOR

4.26e-04311403C1335167
DiseaseGlobal developmental delay

CACNA1E TMEM94 TRRAP NBAS ZBTB18

4.42e-041331405C0557874
Diseaserecalcitrant atopic dermatitis

THEMIS NBAS

4.62e-0471402EFO_1000651
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP12A

4.62e-0471402DOID:0060178 (implicated_via_orthology)
Diseasesleep duration, circadian rhythm, excessive daytime sleepiness measurement, insomnia measurement

PATJ HCRTR2

6.14e-0481402EFO_0004354, EFO_0005271, EFO_0007875, EFO_0007876
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 FPGT CSMD3 MTOR SCARB1

7.19e-041481405C0279702
Diseaseasparagine measurement

PIWIL4 CERT1 RFX3

9.77e-04411403EFO_0009766
DiseaseAnorectal Malformations

INTU NLGN1 FANCB

9.77e-04411403C3495676
Diseasealpha wave measurement, electroencephalogram measurement

NOX3 DNAH1

9.81e-04101402EFO_0004357, EFO_0006870
DiseaseParanoia

DBH TYK2

1.20e-03111402C1456784
Diseasequality of life during menstruation measurement, dysmenorrheic pain measurement

IL1B VPS13B

1.20e-03111402EFO_0007889, EFO_0009366
DiseaseSecondary Open Angle Glaucoma

WDR36 MYOC

1.43e-03121402C0271148
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP12A

1.43e-03121402DOID:863 (implicated_via_orthology)
DiseaseGlaucoma, Open-Angle

WDR36 MYOC

1.43e-03121402C0017612
DiseaseX-12707 measurement

DBH ARSL

1.43e-03121402EFO_0800720
Diseasesystemic lupus erythematosus (is_marker_for)

SELL TAB3 IL1B

1.45e-03471403DOID:9074 (is_marker_for)
Diseasecolitis (implicated_via_orthology)

SELL IL1B

1.68e-03131402DOID:0060180 (implicated_via_orthology)
DiseaseGlaucoma, Primary Open Angle

WDR36 MYOC

1.68e-03131402C0339573
DiseaseAlcoholic Intoxication, Chronic

THEMIS MPDZ DBH NLGN4X TESK2 IL1B

1.81e-032681406C0001973
Diseaseabdominal aortic aneurysm (biomarker_via_orthology)

SELL IL1B

1.96e-03141402DOID:7693 (biomarker_via_orthology)
Diseasenon-high density lipoprotein cholesterol measurement

MBTD1 DAND5 TMBIM6 CERT1 TYK2 ARSL CD163L1 NYNRIN SCARB1 PCCB

2.20e-0371314010EFO_0005689
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKHD1

2.57e-03161402DOID:0110861 (implicated_via_orthology)
Diseasesugar consumption measurement

MYOC NBAS PKHD1 VPS13B

2.61e-031201404EFO_0010158
Diseasetestosterone measurement

ZAN CECR2 DENND2D CSMD3 RYK TYK2 NF1 CGB2 PDE8B NYNRIN SCARB1 ATP12A PCCB DNPEP

3.03e-03127514014EFO_0004908
Diseaseandrostenedione measurement, estrone measurement

OR4D2 BMPER

3.25e-03181402EFO_0007970, EFO_0007972
Diseasechronic obstructive pulmonary disease (is_implicated_in)

IL13RA1 RTEL1 IL1B

3.37e-03631403DOID:3083 (is_implicated_in)
Diseasesensorineural hearing loss (implicated_via_orthology)

SCARB1 DNAH17

3.63e-03191402DOID:10003 (implicated_via_orthology)
Diseasemyocardial infarction (implicated_via_orthology)

MAP3K5 MTOR IL1B

3.85e-03661403DOID:5844 (implicated_via_orthology)
DiseaseSeizures

CACNA1E MPDZ TRRAP ATP1A1 IL1B

3.91e-032181405C0036572
Diseaseradiation-induced disorder

NOX3 WDR91 NELL2

4.01e-03671403EFO_0009565
Diseaseend stage renal disease (implicated_via_orthology)

MTOR IL1B

4.02e-03201402DOID:783 (implicated_via_orthology)
DiseaseCocaine Dependence

DBH TYK2 SCARB1 LRRC7

4.41e-031391404C0600427
Diseasehyperglycemia (biomarker_via_orthology)

IL1B HCRTR2

4.42e-03211402DOID:4195 (biomarker_via_orthology)
Diseasestatus epilepticus (implicated_via_orthology)

MTOR IL1B

4.42e-03211402DOID:1824 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ELPSECNVGPVMSRQ

nan

181

A8MWP4
LSVRLCPPVSGQAAM

GPT2

371

Q8TD30
CPPVSGQAAMDIVVN

GPT2

376

Q8TD30
IQFANGTEELPVPLM

nan

366

Q9N2K0
ITEQPMCFQRTTPLI

ARSL

261

P51690
ERLQMDGAPPVCQVL

CSMD3

2441

Q7Z407
LSPQDIFQLACMDPA

CACNA1E

1941

Q15878
PLQDLMVRNDTPCGT

DNPEP

411

Q9ULA0
VSPSVCLDQGMQLKP

CPED1

211

A4D0V7
SLLSCFPNVQMLPLD

A4GALT

131

Q9NPC4
ISFRLEPGTTPCQVM

ADGRD1

621

Q6QNK2
VIPLNGTIMPCDAVL

ATP13A3

296

Q9H7F0
ELNVLPFCTQFIPMD

ALDH1L2

101

Q3SY69
MQEEIFGPVLPIVCV

ALDH3A1

331

P30838
AQALGRQLVMLPCSP

DNHD1

1701

Q96M86
LDNCQMTVLGAPPCI

CD163L1

976

Q9NR16
IAMQQLSSRVCPPGV

CECR2

906

Q9BXF3
VVSQIFPCEMIPAVL

AP4E1

156

Q9UPM8
PYQPLIAIGSICGMI

CFAP251

616

Q8TBY9
TVLQPLCLGESPVVM

RAI2

76

Q9Y5P3
ILTMNQTQGLCPEIP

P2RX4

106

Q99571
CPAILNPRMFNIISD

RASA1

906

P20936
CEPIGLQVPPEAVNM

ITGAX

76

P20702
RSMEQIVFPVPGICQ

ITPR3

2131

Q14573
PPVIMGLQLDFCDSS

OR6C65

156

A6NJZ3
ENLTNVMSGFCLPEP

ACACB

1001

O00763
CALIGMSPQVNAVFP

ANO10

571

Q9NW15
VAMICQTLVSPPEGN

CERT1

551

Q9Y5P4
INIIGLAPLCENMPS

LAP3

326

P28838
IVMISTLPFCGPNQI

OR6K3

176

Q8NGY3
LNPQEVIQGMCKAVP

DAND5

91

Q8N907
KMLVPCPQTFQENDL

IL1B

76

P01584
SIVQLALMLPLPFCG

OR4D2

156

P58180
MIQILFTFQLPFCGP

OR4C15

156

Q8NGM1
PQIMIFPEGTCTNRT

LPCAT1

201

Q8NF37
GGMNPQECLPVILDV

ME1

181

P48163
LVMPQGFIAQCPDLN

NELL2

211

Q99435
FPVGFCEINMIELTP

MBTD1

441

Q05BQ5
ISGLQQERSMCTPLP

LRRC7

531

Q96NW7
VPSLMPCQGFCLNVV

GPC2

266

Q8N158
MELLCDAQGTPQPNI

HMCN2

3521

Q8NDA2
SNLCFVGLLSMIDPP

ATP12A

596

P54707
DNLCFVGLISMIDPP

ATP1A1

581

P05023
SCIAVPPLEGFVMNR

FAM91A1

231

Q658Y4
GCPLRMVVQESQLTP

FREM2

706

Q5SZK8
CGTDTMLGQPLQLLP

HERC1

1786

Q15751
LCPNMISTQPQEFVG

LMLN

251

Q96KR4
PQPVASVLIMNCRIG

ITGAE

896

P38570
MCVIPATISNNVPGT

PFKL

521

P17858
MPITINDVPPCISQL

PDE8B

536

O95263
PICFQGPFVQVDELM

CSTF3

626

Q12996
TNCPTLIVMVGLPAR

PFKFB4

36

Q16877
LLACQPQVPSAQVMD

GCGR

16

P47871
IITMCLNSLPDFQIP

KCNS2

201

Q9ULS6
FGPEMPAVQLLLLAC

MYOC

11

Q99972
LPQGMLNSPTICQTF

HERVK_113

161

P63132
CQFLEGSPAMLPVQP

PMS2P5

86

A8MQ11
VIQCEPLSAPDLGIM

SELL

256

P14151
CQMLADNVPVTVPVG

KNTC1

1111

P50748
VCPQNIIDGRLPEVM

NLGN1

116

Q8N2Q7
SIIQVILMLPFPFCG

OR4D6

156

Q8NGJ1
PPIILMTQVDFCVSN

OR6C4

156

Q8NGE1
VAMTDLCPAGPIQAV

FAAP100

771

Q0VG06
EPECGNTPNAMTILL

ITGB5

711

P18084
PEMAIALTPFQGLCG

MPI

136

P34949
LPEACFNGDSLMIIP

NBAS

776

A2RRP1
LPQGMLNSPTICQTF

ERVK-7

161

P63135
LPQGMLNSPTICQTF

ERVK-6

161

Q9BXR3
CFMVPGVLPDTLNTV

IL13RA1

296

P78552
SCVPESMQPFDLLGI

MVB12B

266

Q9H7P6
ETLPPTCQGNLLIMG

NUTM1

856

Q86Y26
VCQLPFGDPCAVQLM

FANCB

276

Q8NB91
TENIERVLSCIPGPM

INTU

241

Q9ULD6
ASGVIPQISLIMGPC

PCCB

186

P05166
LPQGMLNSPTICQTF

ERVK-18

161

Q9QC07
PQAIVMECSTVFPGL

HCRTR2

186

O43614
CPTMTRVLQGVLPAL

CGB2

56

Q6NT52
IPLVPSCAVFITMNP

DNAH1

1671

Q9P2D7
LPQPQQCSLFSVMEL

CNPPD1

386

Q9BV87
VLQIPFITDNPCIMC

BMPER

56

Q8N8U9
LTFGINPFIALMIQP

C2orf83

6

Q53S99
PGNPMLNIIVSTFIF

CASD1

731

Q96PB1
LNAAGMIIPCLGFPQ

DNAH17

56

Q9UFH2
ACTMEVQAPNIQIPS

DBH

211

P09172
VPFCGQEVTDPVQMI

GIMD1

116

P0DJR0
VCFVSNLFPPMLTVN

HLA-DMA

146

P28067
ILPVMQSLCPDGQRD

ABCA2

66

Q9BZC7
CIAVNPSILPTAFMG

TMBIM6

106

P55061
IQEPNTFPAILRSMC

GNS

126

P15586
SPVLNAFVMPICLPE

MASP1

561

P48740
AFVMPICLPEGPQQE

MASP1

566

P48740
ICLPEGPQQEGAMVI

MASP1

571

P48740
VVLICPQDGMEAIPN

LSM7

81

Q9UK45
ANVREPICGFTPLME

ANKS3

161

Q6ZW76
QMGLVIEPPQCQFAQ

EFHB

211

Q8N7U6
GSGEAMLQLIPPFQC

C6orf89

286

Q6UWU4
FMCAQLPNPVLDSIS

EHD1

136

Q9H4M9
VPCLSTRLINPENMG

SACS

1436

Q9NZJ4
IAQPINCPDELFAVM

RYK

561

P34925
MQIVQGFPADAPLCA

DSCR10

1

P59022
DGCLQFLVPMLQDFP

HCN2

381

Q9UL51
PLLFTPVCVMLNSNV

NLGN4X

11

Q8N0W4
LQVTCQQMPPFICGA

CEBPZ

591

Q03701
DFPLNMNPGILVTCA

FPGT

166

O14772
LATVCCPTPFMVGVQ

DENND2D

296

Q9H6A0
MACPALGLEALQPLQ

LIMCH1

1

Q9UPQ0
PVLGLVQNMSVFQCP

NUBPL

231

Q8TB37
PPVMLLLQLDFCASN

OR6C75

156

A6NL08
VSALCLMAPNSQLPF

NYNRIN

1146

Q9P2P1
FLIPIVLISQMPFCG

OR11H1

171

Q8NG94
VLISQMPFCGPNIID

OR11H1

176

Q8NG94
FLIPIVLISQMPFCG

OR11H12

171

B2RN74
VLISQMPFCGPNIID

OR11H12

176

B2RN74
PVCLSRELGVMQPGQ

OTOG

2686

Q6ZRI0
SLGLKCVQFLPQVMP

MTOR

981

P42345
CVQFLPQVMPTFLNV

MTOR

986

P42345
PQVMPTFLNVIRVCD

MTOR

991

P42345
ELMQPNFELLLGPIC

MAP3K5

236

Q99683
EMQIPFPVCLENPHI

RTEL1

491

Q9NZ71
IPVNQDCILDGFPMT

SPEF2

716

Q9C093
AICFGPTLMPVPEIQ

SRGAP1

656

Q7Z6B7
PTLMPVPEIQDQVSC

SRGAP1

661

Q7Z6B7
PEIPEGVVSQCMLQN

TAB3

21

Q8N5C8
KTELSQAFPVGCMQP

RFX3

696

P48380
QAFPVGCMQPVLETG

RFX3

701

P48380
GCMQPVLETGVQPSL

RFX3

706

P48380
PPETCQMEAGSLFLL

SPATA31A6

306

Q5VVP1
DCQFLEGSPAMLPVQ

PMS2P2

256

O95744
MPALESLCLQGPLVT

FBXL12

251

Q9NXK8
PPETCQMEAGSLFLL

SPATA31A7

306

Q8IWB4
DPDVQLVMCILPSNQ

PIWIL4

541

Q7Z3Z4
PQLILVNMASFPECT

MRRF

141

Q96E11
PVTGIPMNCSVKLQL

SCARB1

376

Q8WTV0
PGMVSRILFPDQVAC

SLC5A11

326

Q8WWX8
PMVFVDDQLPCNVTF

PKHD1

1516

P08F94
KMAPGQYILVQCPAI

NOX3

316

Q9HBY0
NTRGQIPPLVTTDCM

SEC24D

286

O94855
IPPLVTTDCMIQDQG

SEC24D

291

O94855
PEQLIPFAGICMFIL

SLC28A2

171

O43868
NVLPFCSQFIPMEII

ALDH1L1

81

O75891
QLGPLMCQFGLPAEA

ADRM1

351

Q16186
LCAGQVTALPVNSPM

CHGA

11

P10645
FLEMPLRQSGLCQPE

C11orf16

371

Q9NQ32
LPQGMLNSPTICQTF

ERVK-25

161

P63136
AGPLTFNEMIQPVCL

TMPRSS3

311

P57727
PPETCQMEAGSLFLL

SPATA31A3

306

Q5VYP0
QIEGCESLQPFELPM

THEMIS

66

Q8N1K5
VNQMAVCPGNAVEPL

MPDZ

1436

O75970
PPETCQMEAGSLFLL

SPATA31A5

306

Q5VU36
RDNMSVILICFPNAP

PPM1A

281

P35813
QVPGQSSIFTMCELP

TMEM94

771

Q12767
ATCPIVPGQEMIIEI

PATJ

1426

Q8NI35
PIGLNMCTPGDQELI

RYR3

3376

Q15413
PCIAEFMPILGTNLN

TNPO2

701

O14787
NILSPAGQIFMCPLC

ZBTB18

361

Q99592
LPQGMLNSPTICQTF

ERVK-10

161

P10266
LPQGMLNSPTICQTF

ERVK-8

161

P63133
RPEMFIIGAQPVCSQ

WNT5B

36

Q9H1J7
LPIAMALANVVPCSQ

NF1

1221

P21359
LPQGMLNSPTICQTF

ERVK-11

161

Q9UQG0
VYIGGMPCELLIPQS

PKHD1L1

191

Q86WI1
PPNMGQDICFVLLAL

TGM5

516

O43548
DVVCMSLANVPPGEQ

SF3B3

586

Q15393
DCQNMLFPIKPGETQ

ZNF717

161

Q9BY31
MVGECQFAVPVPKPL

TOPAZ1

1016

Q8N9V7
GQTSMPGTLVLCLPQ

VPS13B

1106

Q7Z7G8
MCQPVARGFVVLPIT

TMEM130

116

Q8N3G9
NMGCAVINPEPITLT

TASOR2

1041

Q5VWN6
MVGDCPPDFLQLTFN

TESK2

276

Q96S53
DLCLAMAVQTPVPTA

RIPOR1

771

Q6ZS17
NFLSVLFQCMPVPVI

WDR91

161

A4D1P6
LFQCMPVPVILNFDA

WDR91

166

A4D1P6
MVAVAQQCGPFLLPC

TRRAP

1051

Q9Y4A5
CLPQPGETSNLIIMR

TYK2

551

P29597
PSIVMLPGTCQTQDV

WDR36

711

Q8NI36
VVAMGFILINPGTCP

ZAN

521

Q9Y493