Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	GAIN_dom_N	CELSR1 CELSR2	3.96e-04	11	51	2	IPR032471
Domain	GAIN	CELSR1 CELSR2	3.96e-04	11	51	2	PF16489
Domain	zf-CCHC	TUT4 ZCCHC2	1.78e-03	23	51	2	PF00098
Domain	HormR	CELSR1 CELSR2	2.11e-03	25	51	2	SM00008
Domain	-	TUT4 ZCCHC2	2.28e-03	26	51	2	4.10.60.10
Domain	HRM	CELSR1 CELSR2	2.64e-03	28	51	2	PF02793
Domain	EGF_LAM_2	CELSR1 CELSR2	3.03e-03	30	51	2	PS50027
Domain	EGF_LAM_1	CELSR1 CELSR2	3.03e-03	30	51	2	PS01248
Domain	GPS	CELSR1 CELSR2	3.88e-03	34	51	2	SM00303
Domain	GPS	CELSR1 CELSR2	4.11e-03	35	51	2	PF01825
Domain	Laminin_EGF	CELSR1 CELSR2	4.11e-03	35	51	2	PF00053
Domain	ZF_CCHC	TUT4 ZCCHC2	4.11e-03	35	51	2	PS50158
Domain	EGF_Lam	CELSR1 CELSR2	4.11e-03	35	51	2	SM00180
Domain	GPS	CELSR1 CELSR2	4.34e-03	36	51	2	PS50221
Domain	PTPc	PTPN5 PTPN23	4.34e-03	36	51	2	SM00194
Domain	GPS	CELSR1 CELSR2	4.58e-03	37	51	2	IPR000203
Domain	LAM_G_DOMAIN	CELSR1 CELSR2	4.83e-03	38	51	2	PS50025
Domain	Laminin_EGF	CELSR1 CELSR2	4.83e-03	38	51	2	IPR002049
Domain	TYR_PHOSPHATASE_PTP	PTPN5 PTPN23	5.08e-03	39	51	2	PS50055
Domain	G_PROTEIN_RECEP_F2_1	CELSR1 CELSR2	5.34e-03	40	51	2	PS00649
Domain	GPCR_2_extracellular_dom	CELSR1 CELSR2	5.34e-03	40	51	2	IPR001879
Domain	Laminin_G_2	CELSR1 CELSR2	5.34e-03	40	51	2	PF02210
Domain	G_PROTEIN_RECEP_F2_3	CELSR1 CELSR2	5.34e-03	40	51	2	PS50227
Domain	EGF-like_CS	CELSR1 CELSR2 ADAM17 ITGB4	5.57e-03	261	51	4	IPR013032
Domain	PTPase_domain	PTPN5 PTPN23	5.60e-03	41	51	2	IPR000242
Domain	Y_phosphatase	PTPN5 PTPN23	5.60e-03	41	51	2	PF00102
Domain	PSI	SEMA5A ITGB4	6.43e-03	44	51	2	IPR016201
Domain	LamG	CELSR1 CELSR2	6.43e-03	44	51	2	SM00282
Domain	PSI	SEMA5A ITGB4	7.01e-03	46	51	2	SM00423
Pubmed	Elevated semaphorin5A in systemic lupus erythematosus is in association with disease activity and lupus nephritis.	SEMA5A ADAM17	2.28e-06	2	53	2	28063160
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	2.28e-06	2	53	2	23292348
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CELSR1 PDE4A ZNF48 KANSL1 CELSR2 SREBF1 CUL9 RPSA ITGB4 AP3D1	5.67e-06	1105	53	10	35748872
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR2	6.83e-06	3	53	2	11677057
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR2	1.36e-05	4	53	2	37224017
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR2	1.36e-05	4	53	2	11850187
Pubmed	Expression patterns of laminin receptor splice variants alpha 6A beta 1 and alpha 6B beta 1 suggest different roles in mouse development.	RPSA ITGB4	1.36e-05	4	53	2	8573717
Pubmed	Mass spectrometry-based proteomics revealed Glypican-1 as a novel ADAM17 substrate.	EIF4B RPSA ADAM17 ITGB4	3.03e-05	116	53	4	27576135
Pubmed	Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.	CELSR1 CELSR2	3.40e-05	6	53	2	36712970
Pubmed	Mitotic internalization of planar cell polarity proteins preserves tissue polarity.	CELSR1 ITGB4	4.76e-05	7	53	2	21743464
Pubmed	Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.	DLG5 KIF7	4.76e-05	7	53	2	25644602
Pubmed	Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.	CELSR1 CELSR2	4.76e-05	7	53	2	17937400
Pubmed	Variants in several genomic regions associated with asperger disorder.	SLTM FHIT	4.76e-05	7	53	2	21182207
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	YEATS2 EIF4B PTPN23 RPSA OCRL PRMT7 AP3D1 XAB2	7.98e-05	934	53	8	33916271
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	CELSR1 CELSR2	1.24e-04	11	53	2	25024228
Pubmed	Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.	CELSR1 CELSR2	1.49e-04	12	53	2	11891983
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR1 CELSR2	1.49e-04	12	53	2	20631168
Pubmed	Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles.	CELSR1 ITGB4	1.76e-04	13	53	2	18849982
Pubmed	A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.	CELSR1 CELSR2	1.76e-04	13	53	2	26989192
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	CELSR1 TMEM79 AP3D1	1.85e-04	72	53	3	25917818
Pubmed	Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration.	CELSR1 TMEM79	2.05e-04	14	53	2	35649377
Pubmed	Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.	CELSR1 CELSR2	2.05e-04	14	53	2	39225402
Pubmed	APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.	TFAP2B AP3D1	2.05e-04	14	53	2	29262337
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR1 CELSR2	2.36e-04	15	53	2	20473291
Pubmed	Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.	KCNA5 TFAP2B	2.70e-04	16	53	2	17444492
Pubmed	MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters.	KANSL1 ITGB4	3.05e-04	17	53	2	37479688
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	SLTM AP3D1 XAB2	3.57e-04	90	53	3	35654790
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	PTPN5 EFHC1 KANSL1 TMEM79 PTPN23 PRPF38A FHIT JAKMIP2 NT5C	3.59e-04	1477	53	9	31515488
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	DLG5 EIF4B MRPL19 RPSA	3.96e-04	226	53	4	25900982
Pubmed	Local regulation of fat metabolism in peripheral nerves.	SREBF1 ITGB4	5.65e-04	23	53	2	14522948
Pubmed	Primary cilia in murine palatal rugae development.	CELSR1 CELSR2	5.65e-04	23	53	2	31226309
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	CELSR1 CELSR2	7.23e-04	26	53	2	37228654
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	ZNF48 SLTM MRPL19 RPSA PRPF38A XAB2	7.36e-04	713	53	6	29802200
Pubmed	Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis.	DLG5 ITGB4	7.80e-04	27	53	2	23466739
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	DLG5 EIF4B ITGB4	7.88e-04	118	53	3	30979931
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	DLG5 LCT	8.40e-04	28	53	2	19422935
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	CELSR2 SREBF1	9.01e-04	29	53	2	20167577
Pubmed	Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.	FHIT NXN	1.10e-03	32	53	2	24954895
Pubmed	Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.	CELSR1 CELSR2	1.10e-03	32	53	2	23177622
Pubmed	Primary Ciliary Dyskinesia	CCNO HYDIN	1.10e-03	32	53	2	20301301
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	CELSR1 CELSR2	1.17e-03	33	53	2	25713288
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DLG5 SLTM MRPL19 RPSA PRPF38A AP3D1 XAB2	1.22e-03	1082	53	7	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	EIF4B SLTM PTPN23 ADAM17 PRPF38A ZCCHC2 ITGB4	1.24e-03	1084	53	7	11544199
Pubmed	Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.	AGBL5 HYDIN	1.31e-03	35	53	2	37890489
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	CELSR1 CUL9 AP3D1	1.34e-03	142	53	3	19851296
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	CELSR1 CUL9 AP3D1	1.37e-03	143	53	3	20198315
Pubmed	Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.	PTPN5 KCTD8 OCRL	1.37e-03	143	53	3	32560809
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	NAE1 EIF4B OCRL KIF7	1.46e-03	321	53	4	32098917
Interaction	FDCSP interactions	SLTM PRPF38A FHIT	3.51e-06	12	52	3	int:FDCSP
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	NFATC3 NAE1 PRMT7 HYDIN	6.14e-05	183	53	4	chr16q22
Cytoband	16q22.2	NFATC3 HYDIN	2.98e-04	22	53	2	16q22.2
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	8.53e-06	3	31	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	8.53e-06	3	31	2	1189
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN5 PTPN23	4.28e-04	18	31	2	812
GeneFamily	Zinc fingers CCHC-type\|RNA binding motif containing	TUT4 ZCCHC2	8.33e-04	25	31	2	74
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#2_top-relative-expression-ranked_200	TUT4 KANSL1 MRPL19 TFAP2B	6.40e-05	88	52	4	gudmap_developingKidney_e15.5_200_k2
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_500	TUT4 KANSL1 MRPL19 SEMA5A	8.29e-05	94	52	4	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_500_k4
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000	CELSR1 TUT4 KANSL1 CELSR2 EIF4B AUTS2 MRPL19 SEMA5A TFAP2B	1.20e-04	795	52	9	gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000	TUT4 KANSL1 MRPL19 SEMA5A OCRL TFAP2B	1.74e-04	339	52	6	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500	TUT4 KANSL1 MRPL19 TFAP2B	1.93e-04	117	52	4	gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000	TUT4 KANSL1 MRPL19 SEMA5A TFAP2B	2.26e-04	226	52	5	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_200	KANSL1 MRPL19 TFAP2B	2.65e-04	51	52	3	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_200_k4
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_200	TUT4 KANSL1 SEMA5A	3.15e-04	54	52	3	gudmap_developingKidney_e15.5_cortic collect duct_200_k3
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	TUT4 KANSL1 EIF4B MRPL19 SEMA5A TFAP2B	3.16e-04	379	52	6	gudmap_developingKidney_e15.5_1000_k3
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CELSR2 RPSA NXN ITGB4	2.80e-06	186	53	5	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CELSR2 RPSA NXN ITGB4	3.02e-06	189	53	5	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	CELSR1 EFHC1 CCNO JAKMIP2 HYDIN	3.79e-06	198	53	5	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	CELSR1 EFHC1 CCNO JAKMIP2 HYDIN	3.79e-06	198	53	5	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	COVID-CD8-exh_CD4\|COVID / Condition, Cell_class and T cell subcluster	YEATS2 ZNF48 ARHGEF5 PTPN23	4.55e-05	166	53	4	4ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	YEATS2 RASIP1 CUL9 JAKMIP2	5.22e-05	172	53	4	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CELSR1 CELSR2 CCNO ITGB4	5.71e-05	176	53	4	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	Epithelial-basal_cell\|World / Lineage, Cell type, age group and donor	CELSR1 CCNO NXN ITGB4	6.09e-05	179	53	4	d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	CELSR1 SEMA5A NXN ITGB4	6.36e-05	181	53	4	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	Control-Epithelial-Basal\|World / Disease state, Lineage and Cell class	CELSR1 SEMA5A NXN ITGB4	6.50e-05	182	53	4	759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCell	Control-Epithelial-Basal\|Control / Disease state, Lineage and Cell class	CELSR1 SEMA5A NXN ITGB4	6.50e-05	182	53	4	caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASIP1 CELSR1 NXN ITGB4	6.50e-05	182	53	4	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	COPD-Epithelial-Basal\|COPD / Disease state, Lineage and Cell class	CELSR1 SEMA5A NXN ITGB4	6.64e-05	183	53	4	0f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KANSL1 NAE1 ADAM17 JAKMIP2	7.07e-05	186	53	4	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA5A FHIT HYDIN FAM135B	7.07e-05	186	53	4	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASIP1 KCNA5 NXN ITGB4	7.07e-05	186	53	4	5302399825f213d105ac70b91366a4513b732838
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	CELSR1 SEMA5A NXN ITGB4	7.22e-05	187	53	4	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA5 KCTD8 AUTS2 OCRL	7.52e-05	189	53	4	fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	CELSR1 SEMA5A NXN ITGB4	7.99e-05	192	53	4	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CELSR1 EFHC1 CFAP74 HYDIN	8.15e-05	193	53	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 ARHGEF5 TMEM79 ITGB4	8.15e-05	193	53	4	22ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCell	facs-Tongue\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CELSR2 TMEM79 ITGB4	8.49e-05	195	53	4	77128895db9221a64a171082d468ebcd6380c936
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLG5 CELSR1 SEMA5A ITGB4	8.83e-05	197	53	4	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CELSR1 CCNO JAKMIP2 HYDIN	9.18e-05	199	53	4	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CELSR1 CCNO JAKMIP2 HYDIN	9.18e-05	199	53	4	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLG5 CELSR1 SEMA5A ITGB4	9.36e-05	200	53	4	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	EFHC1 CCNO JAKMIP2 HYDIN	9.36e-05	200	53	4	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Mesenchymal-Cilia-bearing_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	EFHC1 KCNA5 CCNO HYDIN	9.36e-05	200	53	4	c6060205cab46628d845edbf17e2c5be7508181c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	DLG5 CELSR2 AUTS2 MAPK8IP2	9.36e-05	200	53	4	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	EFHC1 CCNO JAKMIP2 HYDIN	9.36e-05	200	53	4	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	lung-Type_I_Pneumocytes\|lung / shred on tissue and cell subclass	ZNF48 KANSL1 JAKMIP2	1.28e-04	82	53	3	6023212a51f8b3e05e6c3dcf4e8fbf53ba696fb2
Drug	Ado-p-CH2-p-ps-Ado	FHIT MAPK8IP2	5.12e-06	2	52	2	CID006858209
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A	DLG5 AP5S1 CUL9 ITGB4 XAB2 MAPK8IP2	5.68e-06	197	52	6	3862_DN
Drug	hemigossypol	LCT NT5C	1.53e-05	3	52	2	CID000115300
Disease	grip strength measurement	LINC01565 CELSR1 KANSL1 AUTS2 OCRL TFAP2B	3.43e-05	350	52	6	EFO_0006941
Disease	Asperger syndrome	SLTM FHIT	6.36e-05	7	52	2	EFO_0003757
Disease	caudate nucleus measurement, functional brain measurement, response to reward	CELSR1 NXN FAM135B	7.92e-05	47	52	3	EFO_0007849, EFO_0008387, EFO_0008396
Disease	cortical surface area measurement	CELSR1 KCNA5 KANSL1 SREBF1 AUTS2 CUL9 SEMA5A RPSA AGBL5 TFAP2B	1.03e-04	1345	52	10	EFO_0010736
Disease	atopic dermatitis (implicated_via_orthology)	TMEM79 ADAM17	1.66e-04	11	52	2	DOID:3310 (implicated_via_orthology)
Disease	colorectal health	AUTS2 SEMA5A FHIT JAKMIP2	4.38e-04	201	52	4	EFO_0008460
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 HYDIN	5.11e-04	19	52	2	DOID:10908 (implicated_via_orthology)
Disease	eye colour measurement	MPST CELSR1 KCNA5 FHIT	5.94e-04	218	52	4	EFO_0009764
Disease	taste liking measurement	RASIP1 KCNA5 KANSL1 AUTS2 FHIT	5.99e-04	388	52	5	EFO_0010155
Disease	cortical thickness	CELSR1 KCNA5 KANSL1 SREBF1 AUTS2 CUL9 RPSA FHIT	6.88e-04	1113	52	8	EFO_0004840
Disease	resistin measurement	LINC01565 XAB2	1.20e-03	29	52	2	EFO_0004819
Disease	Kartagener Syndrome	CCNO HYDIN	1.75e-03	35	52	2	C0022521
Disease	low density lipoprotein cholesterol measurement, C-reactive protein measurement	RASIP1 CELSR2	1.75e-03	35	52	2	EFO_0004458, EFO_0004611
Disease	Polynesian Bronchiectasis	CCNO HYDIN	1.75e-03	35	52	2	C4317124
Disease	pit and fissure surface dental caries	LINC01565 FHIT	1.75e-03	35	52	2	EFO_0006338
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	CCNO HYDIN	1.75e-03	35	52	2	C4551906

Protein segments in the cluster

Peptide	Gene	Start	Entry
LREDREPRLEQLFPD	AGBL5	216	Q8NDL9
RVSRPVDLRLGDHPE	CCNO	296	P22674
VSEHPEAPAREPLRR	ARHGEF5	956	Q12774
THPLPFDMVRERERD	LINC01565	71	O15544
DDPRPHGAERDRLLR	AP5S1	36	Q9NUS5
ARVPRFDTIHEEFPR	CELSR1	2261	Q9NYQ6
EPEELARRQRRHPEL	CELSR2	2226	Q9HCU4
DPRRDYHSVRRPDVL	TFAP2B	136	Q92481
RRPKHRPSEADEEEL	AP3D1	651	O14617
REPVLRFRPREEEAL	RASIP1	541	Q5U651
FRRRFPEEPHVPLEQ	NT5C	26	Q8TCD5
ALRLIERDPYEHPER	PTPN23	1156	Q9H3S7
ERDPYEHPERLRQLQ	PTPN23	1161	Q9H3S7
DRAPPLLHLVREVEE	PTPN5	466	P54829
PEHFPEKERLLREAE	KCTD8	121	Q6ZWB6
FRNLELEERERRSPP	JAKMIP2	586	Q96AA8
AVFRFIPRHPDELEL	MAPK8IP2	611	Q13387
SAERAERERQPHRPI	PDE4A	51	P27815
ERERQPHRPIERADA	PDE4A	56	P27815
IRDPLRDPYRELDIH	AUTS2	1071	Q8WXX7
RDPYRELDIHRRDPL	AUTS2	1076	Q8WXX7
GERRKDRPYVEEPRH	DLG5	1336	Q8TDM6
EEEEEEPPRRTLHLR	KIF7	626	Q2M1P5
ADPEQRHVPLRRRSE	KANSL1	421	Q7Z3B3
PERPEDLRASERFLH	LCT	611	P09848
RPGEERHFELEVFEP	ITGB4	111	P16144
LRPVERFHDLRPDEV	FHIT	41	P49789
RPELELEPRQLHFDR	HYDIN	2931	Q4G0P3
TLPEFRDERELLRHP	KCNA5	271	P22460
RALDFRESREAEPHP	PRMT7	551	Q9NVM4
REVHERNDGRDPFPL	EFHC1	276	Q5JVL4
EVTERDHPLVRPDRS	CUL9	711	Q8IWT3
ELPSDREVLHPFVRR	FAM135B	706	Q49AJ0
FDPRHREEAEELRPI	CFAP74	1501	Q9C0B2
LDEPKLERRPRERHP	EIF4B	391	P23588
FREPRLLVVTDPRAD	RPSA	116	P08865
RLSRPERPDLVFEEE	XAB2	6	Q9HCS7
LGRDARREFEERHIP	MPST	41	P25325
AAAEPEPRRRLEIVF	NXN	76	Q6DKJ4
LKRPRDVDHRRDDPY	SLTM	726	Q9NWH9
IRERRFEIPDEEHCL	OCRL	91	Q01968
EEIELFPERRREPIR	SEMA5A	446	Q13591
ELEPRPTRREHAEAL	SREBF1	1076	P36956
EELVHRVKRRADPDP	ADAM17	206	P78536
EERRHPDLEPILRQL	ZCCHC2	426	Q9C0B9
HRPVEPERRFLSPEF	MRPL19	66	P49406
DLHRPEEREPQRGAR	ZNF48	11	Q96MX3
EIERDLRRSLPEHPA	TBC1D8B	531	Q0IIM8
ALRPFGEPRREVEIH	TMEM79	266	Q9BSE2
PEREFLERPSRDHLY	NFATC3	136	Q12968
DEKLERVPSPDHRRR	PRPF38A	201	Q8NAV1
DPRDLHDTRDFRDPR	TUT4	1341	Q5TAX3
EDLRLDKPFPELREH	NAE1	181	Q13564
SERRSPRPIFDLEFH	PRR23C	206	Q6ZRP0
DLVEVREPPFHLTRR	YEATS2	266	Q9ULM3
AEPPGRRRELLHTEV	ULK3	416	Q6PHR2