Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	cell cortex	ITCH MYO5B SPTBN1 MYRIP FRYL GRM7 SAPCD2 RYR1 IQGAP1 SPTBN5 MISP EXOC7 FCHSD1	8.79e-06	371	166	13	GO:0005938
GeneOntologyCellularComponent	apical cortex	MYO5B SAPCD2 SPTBN5	5.66e-05	10	166	3	GO:0045179
GeneOntologyCellularComponent	cortical actin cytoskeleton	SPTBN1 MYRIP IQGAP1 SPTBN5 MISP FCHSD1	9.87e-05	93	166	6	GO:0030864
GeneOntologyCellularComponent	symmetric, GABA-ergic, inhibitory synapse	NLGN4Y NLGN4X	3.72e-04	4	166	2	GO:0098983
GeneOntologyCellularComponent	glycinergic synapse	NLGN4Y NLGN4X GLRA2	5.08e-04	20	166	3	GO:0098690
GeneOntologyCellularComponent	cortical cytoskeleton	SPTBN1 MYRIP IQGAP1 SPTBN5 MISP FCHSD1	5.83e-04	129	166	6	GO:0030863
GeneOntologyCellularComponent	actin cytoskeleton	WAS MYO5B CARMIL1 SPTBN1 MYRIP SORBS1 ADCY8 IQGAP1 SPTBN5 MISP DIXDC1 RINL FCHSD1	7.13e-04	576	166	13	GO:0015629
GeneOntologyCellularComponent	glutamatergic synapse	MYO5B NLGN4Y SPTBN1 PI4K2A BCAN GRM7 ADCY8 ARF1 SHISA9 NLGN4X ACAN FARP1 NGEF DIXDC1 PLCG1 FBXL20	8.19e-04	817	166	16	GO:0098978
Domain	CH	SYNE1 SPTBN1 IQGAP1 SPTBN5 ASPM DIXDC1	2.10e-05	65	162	6	SM00033
Domain	CH	SYNE1 SPTBN1 IQGAP1 SPTBN5 ASPM DIXDC1	3.22e-05	70	162	6	PF00307
Domain	STAT_TF_alpha	STAT5A STAT5B RNF20	3.47e-05	8	162	3	IPR013800
Domain	-	SYNE1 SPTBN1 IQGAP1 SPTBN5 ASPM DIXDC1	3.49e-05	71	162	6	1.10.418.10
Domain	CH	SYNE1 SPTBN1 IQGAP1 SPTBN5 ASPM DIXDC1	4.09e-05	73	162	6	PS50021
Domain	CH-domain	SYNE1 SPTBN1 IQGAP1 SPTBN5 ASPM DIXDC1	4.77e-05	75	162	6	IPR001715
Domain	NLGN4	NLGN4Y NLGN4X	7.48e-05	2	162	2	IPR030025
Domain	SNF2_N	CHD8 CHD1L RAD54L2 ZRANB3	1.62e-04	32	162	4	IPR000330
Domain	SNF2_N	CHD8 CHD1L RAD54L2 ZRANB3	1.62e-04	32	162	4	PF00176
Domain	FOXO-TAD	FOXO1 FOXO4	2.23e-04	3	162	2	IPR032067
Domain	FOXO-TAD	FOXO1 FOXO4	2.23e-04	3	162	2	PF16676
Domain	PI3_PI4_kinase	PI4K2B SMG1 PI4K2A	4.75e-04	18	162	3	PF00454
Domain	PI3_4_KINASE_1	PI4K2B SMG1 PI4K2A	4.75e-04	18	162	3	PS00915
Domain	PI3_4_KINASE_2	PI4K2B SMG1 PI4K2A	4.75e-04	18	162	3	PS00916
Domain	PI3/4_kinase_cat_dom	PI4K2B SMG1 PI4K2A	4.75e-04	18	162	3	IPR000403
Domain	PI3_4_KINASE_3	PI4K2B SMG1 PI4K2A	4.75e-04	18	162	3	PS50290
Domain	PH	SPTBN1 FERMT1 CERT1 SPTBN5 PLEKHM2 FARP1 NGEF PLCG1 RASAL2	7.34e-04	278	162	9	SM00233
Domain	Nlgn	NLGN4Y NLGN4X	7.35e-04	5	162	2	IPR000460
Domain	PH_DOMAIN	SPTBN1 FERMT1 CERT1 SPTBN5 PLEKHM2 FARP1 NGEF PLCG1 RASAL2	7.53e-04	279	162	9	PS50003
Domain	PH_domain	SPTBN1 FERMT1 CERT1 SPTBN5 PLEKHM2 FARP1 NGEF PLCG1 RASAL2	7.72e-04	280	162	9	IPR001849
Domain	EGF	BCAN F12 FAT1 CELSR1 FAT2 EGF	8.12e-04	126	162	6	PF00008
Domain	PH	SPTBN1 FERMT1 CERT1 SPTBN5 PLEKHM2 FARP1 NGEF PLCG1	8.86e-04	229	162	8	PF00169
Domain	Spectrin	SYNE1 SPTBN1 SPTBN5	9.99e-04	23	162	3	PF00435
Domain	ACTININ_2	SYNE1 SPTBN1 SPTBN5	9.99e-04	23	162	3	PS00020
Domain	ACTININ_1	SYNE1 SPTBN1 SPTBN5	9.99e-04	23	162	3	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 SPTBN1 SPTBN5	9.99e-04	23	162	3	IPR001589
Domain	Rho_GTPase_activation_prot	DEPDC1 ARHGAP11A FAM13B IQGAP1 RASAL2	1.01e-03	88	162	5	IPR008936
Domain	Dilute_dom	MYO5B RASIP1	1.10e-03	6	162	2	IPR002710
Domain	CP2	TFCP2 TFCP2L1	1.10e-03	6	162	2	PF04516
Domain	CP2	TFCP2 TFCP2L1	1.10e-03	6	162	2	IPR007604
Domain	DIL	MYO5B RASIP1	1.10e-03	6	162	2	PF01843
Domain	DILUTE	MYO5B RASIP1	1.10e-03	6	162	2	PS51126
Domain	DIL	MYO5B RASIP1	1.10e-03	6	162	2	SM01132
Domain	STAT_TF_DNA-bd_sub	STAT5A STAT5B	1.53e-03	7	162	2	IPR012345
Domain	STAT	STAT5A STAT5B	1.53e-03	7	162	2	IPR001217
Domain	STAT_int	STAT5A STAT5B	1.53e-03	7	162	2	SM00964
Domain	STAT_TF_DNA-bd	STAT5A STAT5B	1.53e-03	7	162	2	IPR013801
Domain	STAT_bind	STAT5A STAT5B	1.53e-03	7	162	2	PF02864
Domain	STAT_int	STAT5A STAT5B	1.53e-03	7	162	2	PF02865
Domain	-	STAT5A STAT5B	1.53e-03	7	162	2	1.10.532.10
Domain	STAT_alpha	STAT5A STAT5B	1.53e-03	7	162	2	PF01017
Domain	-	STAT5A STAT5B	1.53e-03	7	162	2	1.20.1050.20
Domain	STAT_TF_prot_interaction	STAT5A STAT5B	1.53e-03	7	162	2	IPR013799
Domain	STAT_TF_coiled-coil	STAT5A STAT5B	1.53e-03	7	162	2	IPR015988
Domain	-	STAT5A STAT5B	1.53e-03	7	162	2	2.60.40.630
Domain	Spectrin_repeat	SYNE1 SPTBN1 SPTBN5	1.98e-03	29	162	3	IPR002017
Domain	PIWI	PIWIL1 PIWIL4	2.02e-03	8	162	2	PS50822
Domain	Piwi	PIWIL1 PIWIL4	2.02e-03	8	162	2	SM00950
Domain	HATC_C_dom	ZBED1 THAP12	2.02e-03	8	162	2	IPR008906
Domain	Piwi	PIWIL1 PIWIL4	2.02e-03	8	162	2	PF02171
Domain	Dimer_Tnp_hAT	ZBED1 THAP12	2.02e-03	8	162	2	PF05699
Domain	Piwi	PIWIL1 PIWIL4	2.02e-03	8	162	2	IPR003165
Domain	-	WAS SPTBN1 FERMT1 CERT1 SPTBN5 PLEKHM2 FARP1 NGEF PLCG1 RASAL2	2.23e-03	391	162	10	2.30.29.30
Pathway	KEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY	STAT5A STAT5B EGF	2.05e-05	7	120	3	M47430
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MBLAC2 ITCH RTEL1 NLGN4Y SLC22A23 CARMIL1 CAPN1 MYRIP EVC NFASC FRYL CHD1L CERT1 STAT5B SHISA9 SERPINB6 NADSYN1 TULP4 FARP1 NGEF LSS PLCG1 ALG12 MTARC1 KDM4B	5.91e-08	1489	168	25	28611215
Pubmed	FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis.	FOXO1 ACAN FOXO4	4.41e-07	4	168	3	31980519
Pubmed	FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.	FOXO1 ACAN FOXO4	4.41e-07	4	168	3	29963746
Pubmed	Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.	STAT5A STAT5B EGF	1.10e-06	5	168	3	22729867
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CUL1 ITCH CAPN1 SPTBN1 FERMT1 SAE1 MCM7 CHD8 CHD1L HNRNPUL1 SUCLG2 DUS3L IQGAP1 METTL13 SERPINB6 RNF20 ASPM PLCG1 BUB3 NIPBL RASAL2	2.59e-06	1353	168	21	29467282
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 PGS1 ACADM POGK CHD8 COLGALT2 RAD54L2 STAT5B MOGS RNF20 AP4B1 EXOC7 ZBED1 RASAL2	3.70e-06	650	168	14	38777146
Pubmed	Dengue hemorrhagic fever is associated with polymorphisms in JAK1.	SPTBN1 NFASC TLR7 TLR9 OASL THAP12	5.51e-06	91	168	6	20588308
Pubmed	A systematic scan of interactions with tyrosine motifs in the erythropoietin receptor using a mammalian 2-hybrid approach.	STAT5A STAT5B PLCG1	9.10e-06	9	168	3	15644415
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	CUL1 SYNE1 CAPN1 SPTBN1 ZNF805 MCM7 CHD8 HNRNPUL1 RYR1 ARF1 IQGAP1 MOGS RNF20 ELAPOR1 BUB3	9.65e-06	807	168	15	30575818
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	C5orf52 CARMIL1 SPTBN1 FRYL CERT1 RTF1 OPTN BPGM PLEKHM2 VPS13A ASPM SNX31 IFT80 CCDC24 GIMAP6 SPATA25 RASAL2 KDM4B ATG16L2	9.87e-06	1242	168	19	30973865
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	VWA5B2 CRYBG2 RPRD1B EGF TULP4 ELAPOR1 MED12L EXOC7 KDM4B ATG16L2	1.43e-05	371	168	10	15747579
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 RTEL1 SYNE1 NFASC CHD8 RTF1 METTL13 KDM4B	1.48e-05	225	168	8	12168954
Pubmed	Targeting ARF1-IQGAP1 interaction to suppress colorectal cancer metastasis and vemurafenib resistance.	ARF1 IQGAP1	2.32e-05	2	168	2	36396045
Pubmed	Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.	STAT5A STAT5B	2.32e-05	2	168	2	23151802
Pubmed	Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.	STAT5A STAT5B	2.32e-05	2	168	2	26999798
Pubmed	Expression of toll-like receptors in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma--an in vivo and in vitro study.	TLR7 TLR9	2.32e-05	2	168	2	25941114
Pubmed	A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.	STAT5A STAT5B	2.32e-05	2	168	2	31443474
Pubmed	Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.	STAT5A STAT5B	2.32e-05	2	168	2	12377952
Pubmed	Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.	TLR7 TLR9	2.32e-05	2	168	2	24342772
Pubmed	Actin foci facilitate activation of the phospholipase C-γ in primary T lymphocytes via the WASP pathway.	WAS PLCG1	2.32e-05	2	168	2	25758716
Pubmed	A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.	STAT5A STAT5B	2.32e-05	2	168	2	21127177
Pubmed	The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.	STAT5A STAT5B	2.32e-05	2	168	2	16289657
Pubmed	Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.	STAT5A STAT5B	2.32e-05	2	168	2	25552366
Pubmed	Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.	STAT5A STAT5B	2.32e-05	2	168	2	25470773
Pubmed	The Role of TLR7 and TLR9 in the Pathogenesis of Systemic Sclerosis.	TLR7 TLR9	2.32e-05	2	168	2	38892317
Pubmed	Polymorphisms in Toll-Like Receptors (TLRs)-7 and 9 Genes in Indian Population with Progressive and Nonprogressive HIV-1 Infection.	TLR7 TLR9	2.32e-05	2	168	2	30793925
Pubmed	Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.	TLR7 TLR9	2.32e-05	2	168	2	22628437
Pubmed	Constitutively active Stat5A and Stat5B promote adipogenesis.	STAT5A STAT5B	2.32e-05	2	168	2	21431790
Pubmed	Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.	TLR7 TLR9	2.32e-05	2	168	2	27373163
Pubmed	Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.	STAT5A STAT5B	2.32e-05	2	168	2	28500076
Pubmed	STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.	STAT5A STAT5B	2.32e-05	2	168	2	21826656
Pubmed	Human plasmacytoid dendritic cells mount a distinct antiviral response to virus-infected cells.	TLR7 TLR9	2.32e-05	2	168	2	33811059
Pubmed	Effects of Single-Nucleotide Polymorphisms in the TLR7 and TLR9 Genes of Asthmatic Children.	TLR7 TLR9	2.32e-05	2	168	2	30373864
Pubmed	Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.	STAT5A STAT5B	2.32e-05	2	168	2	7720707
Pubmed	STAT5A and STAT5B have opposite correlations with drug response gene expression.	STAT5A STAT5B	2.32e-05	2	168	2	27264955
Pubmed	The SH3 domain, but not the catalytic domain, is required for phospholipase C-gamma1 to mediate epidermal growth factor-induced mitogenesis.	EGF PLCG1	2.32e-05	2	168	2	20621058
Pubmed	FOXOs modulate proteasome activity in human-induced pluripotent stem cells of Huntington's disease and their derived neural cells.	FOXO1 FOXO4	2.32e-05	2	168	2	28973411
Pubmed	Single nucleotide polymorphisms of toll-like receptor 7 and toll-like receptor 9 in hepatitis C virus infection patients from central China.	TLR7 TLR9	2.32e-05	2	168	2	24532514
Pubmed	Sex bias in susceptibility to MCMV infection: implication of TLR9.	TLR7 TLR9	2.32e-05	2	168	2	23028824
Pubmed	The Role of the Oxidative State and Innate Immunity Mediated by TLR7 and TLR9 in Lupus Nephritis.	TLR7 TLR9	2.32e-05	2	168	2	37894915
Pubmed	Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.	STAT5A STAT5B	2.32e-05	2	168	2	22159083
Pubmed	Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.	HNRNPUL1 MTARC1	2.32e-05	2	168	2	32561361
Pubmed	STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.	STAT5A STAT5B	2.32e-05	2	168	2	20008792
Pubmed	STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.	STAT5A STAT5B	2.32e-05	2	168	2	33199496
Pubmed	Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.	NLGN4Y NLGN4X	2.32e-05	2	168	2	23183221
Pubmed	Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice.	TLR7 TLR9	2.32e-05	2	168	2	19944565
Pubmed	Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.	NLGN4Y NLGN4X	2.32e-05	2	168	2	24855039
Pubmed	Emerging roles of TLR7 and TLR9 in murine SLE.	TLR7 TLR9	2.32e-05	2	168	2	19846276
Pubmed	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.	NLGN4Y NLGN4X	2.32e-05	2	168	2	37001827
Pubmed	Increased expression of Toll-like receptors 7 and 9 in myasthenia gravis thymus characterized by active Epstein-Barr virus infection.	TLR7 TLR9	2.32e-05	2	168	2	26723518
Pubmed	The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.	STAT5A STAT5B	2.32e-05	2	168	2	16502315
Pubmed	Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9.	TLR7 TLR9	2.32e-05	2	168	2	26903634
Pubmed	Stat5: an essential regulator of mast cell biology.	STAT5A STAT5B	2.32e-05	2	168	2	12217382
Pubmed	Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma.	TLR7 TLR9	2.32e-05	2	168	2	24990399
Pubmed	Association of single-nucleotide polymorphisms in TLR7 (Gln11Leu) and TLR9 (1635A/G) with a higher CD4T cell count during HIV infection.	TLR7 TLR9	2.32e-05	2	168	2	24747071
Pubmed	Toll-like receptor (TLR) 7 decreases and TLR9 increases the airway responses in mice with established allergic inflammation.	TLR7 TLR9	2.32e-05	2	168	2	24041926
Pubmed	Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.	STAT5A STAT5B	2.32e-05	2	168	2	31599926
Pubmed	DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.	STAT5A STAT5B	2.32e-05	2	168	2	10594041
Pubmed	Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.	STAT5A STAT5B	2.32e-05	2	168	2	21036145
Pubmed	Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.	STAT5A STAT5B	2.32e-05	2	168	2	10486277
Pubmed	Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.	STAT5A STAT5B	2.32e-05	2	168	2	16840779
Pubmed	The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.	STAT5A STAT5B	2.32e-05	2	168	2	15128421
Pubmed	STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.	STAT5A STAT5B	2.32e-05	2	168	2	30377054
Pubmed	Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.	STAT5A STAT5B	2.32e-05	2	168	2	23565285
Pubmed	Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.	STAT5A STAT5B	2.32e-05	2	168	2	32790723
Pubmed	In vivo identification of novel STAT5 target genes.	STAT5A STAT5B	2.32e-05	2	168	2	18492722
Pubmed	Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.	STAT5A STAT5B	2.32e-05	2	168	2	10066807
Pubmed	Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.	STAT5A STAT5B	2.32e-05	2	168	2	10835485
Pubmed	Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.	STAT5A STAT5B	2.32e-05	2	168	2	35464049
Pubmed	Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly.	EGF PLCG1	2.32e-05	2	168	2	12788694
Pubmed	Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.	STAT5A STAT5B	2.32e-05	2	168	2	18286195
Pubmed	Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.	STAT5A STAT5B	2.32e-05	2	168	2	23773921
Pubmed	Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.	TLR7 TLR9	2.32e-05	2	168	2	24711620
Pubmed	Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.	STAT5A STAT5B	2.32e-05	2	168	2	8631883
Pubmed	Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.	STAT5A STAT5B	2.32e-05	2	168	2	11030348
Pubmed	Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.	STAT5A STAT5B	2.32e-05	2	168	2	24878107
Pubmed	Human Plasmacytoid Dendritic Cells and Cutaneous Melanoma.	TLR7 TLR9	2.32e-05	2	168	2	32054102
Pubmed	Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.	STAT5A STAT5B	2.32e-05	2	168	2	12847485
Pubmed	Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.	STAT5A STAT5B	2.32e-05	2	168	2	12835478
Pubmed	Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation.	TFCP2 TFCP2L1	2.32e-05	2	168	2	20661472
Pubmed	Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.	STAT5A STAT5B	2.32e-05	2	168	2	7568026
Pubmed	Identification of STAT5A and STAT5B target genes in human T cells.	STAT5A STAT5B	2.32e-05	2	168	2	24497979
Pubmed	Necrotizing lymphadenitis may be induced by overexpression of Toll-like receptor7 (TLR7) caused by reduced TLR9 transport in plasmacytoid dendritic cells (PDCs).	TLR7 TLR9	2.32e-05	2	168	2	33994431
Pubmed	Overexpression of TLR7 and TLR9 Occurs Before Onset Symptoms In First-Degree Relatives of Rheumatoid Arthritis Patients.	TLR7 TLR9	2.32e-05	2	168	2	34272096
Pubmed	Cofactors required for TLR7- and TLR9-dependent innate immune responses.	TLR7 TLR9	2.32e-05	2	168	2	22423970
Pubmed	Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.	STAT5A STAT5B	2.32e-05	2	168	2	17536022
Pubmed	STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.	STAT5A STAT5B	2.32e-05	2	168	2	17382296
Pubmed	Hyper-responsive Toll-like receptor 7 and 9 activation in NADPH oxidase-deficient B lymphoblasts.	TLR7 TLR9	2.32e-05	2	168	2	26340429
Pubmed	STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.	STAT5A STAT5B	2.32e-05	2	168	2	17911616
Pubmed	STAT5 signaling in sexually dimorphic gene expression and growth patterns.	STAT5A STAT5B	2.32e-05	2	168	2	10486314
Pubmed	The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.	STAT5A STAT5B	2.32e-05	2	168	2	17599554
Pubmed	MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.	STAT5A STAT5B	2.32e-05	2	168	2	24497923
Pubmed	Critical role for the catalytic activity of phospholipase C-gamma1 in epidermal growth factor-induced cell migration.	EGF PLCG1	2.32e-05	2	168	2	20674545
Pubmed	Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.	STAT5A STAT5B	2.32e-05	2	168	2	24335105
Pubmed	Brain STAT5 signaling modulates learning and memory formation.	STAT5A STAT5B	2.32e-05	2	168	2	29460051
Pubmed	Increased expression of TLR7 and TLR9 in alopecia areata.	TLR7 TLR9	2.32e-05	2	168	2	31571275
Pubmed	Up-regulation of Toll-like receptors 7 and 9 and its potential implications in the pathogenic mechanisms of LMNA-related myopathies.	TLR7 TLR9	2.32e-05	2	168	2	29895224
Pubmed	Impact of TLR7 and TLR9 polymorphisms on susceptibility to placental infections and pregnancy complications.	TLR7 TLR9	2.32e-05	2	168	2	34102513
Pubmed	STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.	STAT5A STAT5B	2.32e-05	2	168	2	28606561
Pubmed	Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.	STAT5A STAT5B	2.32e-05	2	168	2	12393407
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	BCAN ACAN	2.14e-04	4	109	2	574
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN1 FERMT1 CERT1 PLEKHM2 FARP1 PLCG1 RASAL2	2.51e-04	206	109	7	682
GeneFamily	I-set domain containing\|IgLON cell adhesion molecules	LSAMP IGLON5	3.56e-04	5	109	2	1052
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN1 SPTBN5	7.42e-04	7	109	2	1113
GeneFamily	Argonaute/PIWI family	PIWIL1 PIWIL4	9.85e-04	8	109	2	408
GeneFamily	CD molecules\|Toll like receptors	TLR7 TLR9	1.57e-03	10	109	2	948
ToppCell	droplet-Lung-nan-18m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B ANPEP TCN1 MYO5B BCAN GALNT13 TFCP2L1 FAT2 ELAPOR1	4.48e-08	189	168	9	ca657353f2b649530809c0bc057e448adc511ec1
ToppCell	droplet-Lung-nan-18m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B ANPEP TCN1 MYO5B BCAN GALNT13 TFCP2L1 FAT2 ELAPOR1	4.48e-08	189	168	9	e5325f1c7430b574947f8ee67e425455b60dc518
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCN1 MYO5B FERMT1 BCAN GALNT13 MISP TFCP2L1 FAT2 ELAPOR1	4.68e-08	190	168	9	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FERMT1 DEPDC1 SAPCD2 F12 MISP FAT2 ASPM SNX31 PRODH	6.97e-08	199	168	9	fe22833e69928a1478df265e1c356c463611dedd
ToppCell	10x5'-Lung-Lymphocytic_B_plasma-Plasmablasts\|Lung / Manually curated celltypes from each tissue	PI4K2B MZB1 SPTBN1 DEPDC1 ARHGAP11A ASPM FUT8 ZBED1	4.15e-07	179	168	8	3fa75eec3e86fd1797eaa33362257df7f9b2a0bf
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	MYO5B CARMIL1 SPTBN1 GALNT13 CNTN6 SH3RF2 FARP1 RASAL2	5.33e-07	185	168	8	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 MYO5B SLC22A23 GALNT13 CNTN6 CELSR1 SH3RF2 IFT80	5.55e-07	186	168	8	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SDK2 MYO5B SLC22A23 GALNT13 CNTN6 CELSR1 ARSD FARP1	5.78e-07	187	168	8	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	droplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B BCAN GALNT13 TFCP2L1 ELAPOR1	6.52e-07	190	168	8	a51405f8466fc6d4087873137472619b2e84c1da
ToppCell	droplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B BCAN GALNT13 TFCP2L1 ELAPOR1	6.52e-07	190	168	8	059beca1c92181b8ba4dcd6fc71ff7530d83d0de
ToppCell	droplet-Lung-18m-Epithelial-alveolar_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B BCAN GALNT13 TFCP2L1 ELAPOR1	6.78e-07	191	168	8	caed913e7ede9f8ae3af273d1ecf375de6c5e813
ToppCell	droplet-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANPEP TCN1 MYO5B FERMT1 BCAN TFCP2L1 ELAPOR1 CCDC24	6.78e-07	191	168	8	1b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCell	facs-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B TCN1 MYO5B BCAN TFCP2L1 FAT1 CELSR1 ELAPOR1	7.05e-07	192	168	8	cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYO5B SLC22A23 CNTN6 MISP CELSR1 SH3RF2 FARP1 IFT80	9.24e-07	199	168	8	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO5B SLC22A23 CNTN6 MISP CELSR1 SH3RF2 FARP1 IFT80	9.59e-07	200	168	8	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO5B SLC22A23 MYRIP TFCP2L1 CELSR1 EGF FARP1 ELAPOR1	9.59e-07	200	168	8	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFASC DEPDC1 GALNT13 SHISA9 NLGN4X NALCN ASPM	4.66e-06	175	168	7	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFASC DEPDC1 GALNT13 SHISA9 NLGN4X NALCN ASPM	4.66e-06	175	168	7	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFASC DEPDC1 GALNT13 SHISA9 NLGN4X NALCN ASPM	4.66e-06	175	168	7	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFASC DEPDC1 GALNT13 SHISA9 NLGN4X NALCN ASPM	4.66e-06	175	168	7	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CARMIL1 FERMT1 COLGALT2 GALNT13 MCTP1 FUT8 RASAL2	5.40e-06	179	168	7	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B SLC22A23 CNTN6 MISP CELSR1 SH3RF2 FARP1	5.81e-06	181	168	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Late_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ANPEP MYO5B GRM7 RPRD1B MISP NGEF FOXO4	6.03e-06	182	168	7	f8257c884393f168f605d371e0840cfca8d3657e
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CARMIL1 FERMT1 COLGALT2 GALNT13 IQGAP1 MCTP1 FUT8	6.03e-06	182	168	7	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B SLC22A23 GALNT13 CNTN6 CELSR1 SH3RF2 FARP1	6.47e-06	184	168	7	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	droplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B ANPEP TCN1 MYO5B BCAN TFCP2L1 ELAPOR1	6.71e-06	185	168	7	6938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell	droplet-Lung-nan-21m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B ANPEP TCN1 MYO5B BCAN TFCP2L1 ELAPOR1	6.71e-06	185	168	7	0e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B SLC22A23 CARMIL1 CNTN6 CELSR1 SH3RF2 FARP1	6.95e-06	186	168	7	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	MYO5B CARMIL1 SPTBN1 GALNT13 CNTN6 SH3RF2 FARP1	7.20e-06	187	168	7	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	droplet-Marrow-nan-21m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO1 MZB1 DEPDC1 SAPCD2 BUB3 GIMAP6 ATG16L2	7.45e-06	188	168	7	2c4432cada1273d08cbdc2824922cf578e448ec8
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B BCAN TFCP2L1 FAT1	7.45e-06	188	168	7	068b761a7b6778bc6d6c776b5f09094aac87477e
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B BCAN TFCP2L1 FAT1	7.45e-06	188	168	7	c95134245dab9057eb1f9b54acb371470f9c8b86
ToppCell	droplet-Lung-21m-Epithelial-alveolar_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B BCAN TFCP2L1 FAT1	7.45e-06	188	168	7	3ee321a74f04eb0982c7b4977426946b0ae6e5a9
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FERMT1 MISP FAT1 CELSR1 FAT2 SH3RF2 ELAPOR1	7.98e-06	190	168	7	47e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCell	facs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FERMT1 MISP FAT1 CELSR1 FAT2 SH3RF2 ELAPOR1	7.98e-06	190	168	7	261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCell	droplet-Lung-21m-Epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 MYO5B TFCP2L1 FAT1 ELAPOR1	7.98e-06	190	168	7	50a8ba20f8153279387c335538bc52bf18ac1fc2
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B TCN1 MYO5B BCAN TFCP2L1 CELSR1 ELAPOR1	8.26e-06	191	168	7	c06bbad24e4897b2c3b5015e4de02411ebf75367
ToppCell	facs-Lung-nan-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PI4K2B TCN1 MYO5B BCAN TFCP2L1 CELSR1 ELAPOR1	8.26e-06	191	168	7	5f43f98cfe7a08d61ed55f34808fabfe47f1ac2e
ToppCell	Control-PLT_5\|World / Disease Group and Platelet Clusters	MYRIP MCRIP1 ADCY8 GALNT13 FAT1 FAT2	8.43e-06	126	168	6	4ba753c4e83eb1d41964edfa22135e047f06c481
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 BCAN TFCP2L1 CELSR1 ELAPOR1	8.55e-06	192	168	7	13e4b17d7a592604140777aca235f795df6b3f91
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 BCAN TFCP2L1 CELSR1 ELAPOR1	8.55e-06	192	168	7	f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	SDK2 SLC22A23 FAT1 CELSR1 FAT2 SH3RF2 B4GALNT3	8.55e-06	192	168	7	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PI4K2B ANPEP TCN1 BCAN TFCP2L1 CELSR1 ELAPOR1	8.55e-06	192	168	7	6244541688f85917018a057aa0b3e5972934dfbc
ToppCell	facs-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCN1 MYO5B FERMT1 TFCP2L1 FAT1 FAT2 ELAPOR1	8.84e-06	193	168	7	8e934f127bc763e905c788beabfa867bd559b682
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PI4K2B MYO5B SLC22A23 PIWIL4 CNTN6 FARP1	1.01e-05	130	168	6	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDK2 CARMIL1 DUSP14 ACAN FARP1 DIXDC1 FUT8	1.01e-05	197	168	7	6e111ba16fc8adde782b3f7da250248cddf11228
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDK2 CARMIL1 DUSP14 ACAN FARP1 DIXDC1 FUT8	1.01e-05	197	168	7	4b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDK2 CARMIL1 DUSP14 ACAN FARP1 DIXDC1 FUT8	1.01e-05	197	168	7	ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	MYO5B CARMIL1 CNTN6 MISP CELSR1 FARP1 IFT80	1.04e-05	198	168	7	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MYO5B SLC22A23 CNTN6 MISP CELSR1 SH3RF2 FARP1	1.04e-05	198	168	7	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Caecum-(1)_T_cell-(18)_cycling_gd_T\|Caecum / shred on region, Cell_type, and subtype	MCM7 DEPDC1 BCAN ARHGAP11A RYR1 ASPM RASAL2	1.04e-05	198	168	7	64278d8831c81874937e76b561c53928dfc437c5
ToppCell	facs-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 CARMIL1 DUSP14 ACAN FARP1 DIXDC1 FUT8	1.04e-05	198	168	7	71e847e8c24744d6df4a960348ad2ecf310373b4
ToppCell	Caecum-T_cell-cycling_gd_T\|Caecum / Region, Cell class and subclass	MCM7 DEPDC1 BCAN ARHGAP11A RYR1 ASPM RASAL2	1.04e-05	198	168	7	5b719b67f8384863077070e1eb7e04a320e6dab4
ToppCell	proximal-Epithelial-Proliferating_Basal\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FERMT1 DEPDC1 ARHGAP11A SAPCD2 FAT2 ASPM SNX31	1.08e-05	199	168	7	521ff4ae3437c8ba477a0a42b9da195af976c3ff
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYO5B SLC22A23 CNTN6 MISP CELSR1 FARP1 IFT80	1.08e-05	199	168	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	proximal-Epithelial-Proliferating_Basal-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FERMT1 DEPDC1 ARHGAP11A SAPCD2 FAT2 ASPM SNX31	1.08e-05	199	168	7	e8549b2c4152cb23548351d9cee27c3805892cd8
ToppCell	proximal-3-Epithelial-Proliferating_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FERMT1 DEPDC1 ARHGAP11A SAPCD2 FAT2 ASPM SNX31	1.08e-05	199	168	7	2263bb73d9c5693b44d91d2548305efc1b6e4079
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TCN1 CAPN1 RYR1 TFCP2L1 FAT2 TMTC3 SNX31	1.08e-05	199	168	7	ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FERMT1 BCAN GRM7 GALNT13 SHISA9 MCTP1 NLGN4X	1.11e-05	200	168	7	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FERMT1 BCAN GRM7 GALNT13 SHISA9 MCTP1 NLGN4X	1.11e-05	200	168	7	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FERMT1 BCAN GRM7 GALNT13 SHISA9 MCTP1 NLGN4X	1.11e-05	200	168	7	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYO5B SLC22A23 CNTN6 MISP CELSR1 FARP1 IFT80	1.11e-05	200	168	7	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PAPSS1 ADCY8 GALNT13 TFCP2L1 EGF FARP1 ELAPOR1	1.11e-05	200	168	7	7c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FERMT1 BCAN GRM7 GALNT13 SHISA9 MCTP1 NLGN4X	1.11e-05	200	168	7	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FERMT1 BCAN GRM7 GALNT13 SHISA9 MCTP1 NLGN4X	1.11e-05	200	168	7	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TCN1 MYO5B MYRIP GALNT13 EGF FARP1 ELAPOR1	1.11e-05	200	168	7	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells-Neuroepithelial_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	SAE1 MCM7 DEPDC1 ARHGAP11A SAPCD2 ASPM BUB3	1.11e-05	200	168	7	55501f83409e0174c756a13ad8077f5b59975e27
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Stem_cells\|6m / Sample Type, Dataset, Time_group, and Cell type.	SAE1 MCM7 DEPDC1 ARHGAP11A SAPCD2 ASPM BUB3	1.11e-05	200	168	7	b9aad527d3ad5bc701e93fa2afdebf695b2a74bb
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	FERMT1 BCAN GRM7 GALNT13 SHISA9 MCTP1 NLGN4X	1.11e-05	200	168	7	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYRIP NFASC ADCY8 GALNT13 FAT1 FAT2	1.30e-05	136	168	6	27a41463e6f16deb5b1d4f17fefded9959038c07
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYRIP NFASC ADCY8 GALNT13 FAT1 FAT2	1.30e-05	136	168	6	88b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NLGN4Y DEPDC1 ARHGAP11A ASPM B4GALNT3 CCDC24	2.36e-05	151	168	6	c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CHRNA9 DUSP14 MYRIP TFCP2L1 BPGM NLGN4X	2.45e-05	152	168	6	655d47efe0608d729801f1f01668e84c1bc0675f
ToppCell	Basal_cells-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CRYBG2 SDK2 FERMT1 ZNF300 FAT2 ELAPOR1	3.27e-05	160	168	6	b223cc47e68a29df4758c5ccf8f6dbffe2a6fa1d
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN CHRNA9 GRM7 RYR1 CNTN6 LSAMP	3.63e-05	163	168	6	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBG2 RELN MZB1 DUSP14 SAPCD2 FUT8	3.75e-05	164	168	6	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBG2 RELN MZB1 DUSP14 SAPCD2 FUT8	3.75e-05	164	168	6	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MZB1 SLC22A23 DUSP14 EVC ERMAP	3.88e-05	165	168	6	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	NLGN4Y MYRIP DEPDC1 ASPM PLCG1 GIMAP6	4.29e-05	168	168	6	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	Basal_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	SDK2 NLGN4Y FERMT1 FAT2 ACAN SNX31	4.29e-05	168	168	6	48089fa2d4a0f31a72405717119b767a92571f01
ToppCell	Dividing_Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	PIWIL1 DEPDC1 ARHGAP11A SAPCD2 ASPM ZNF543	4.44e-05	169	168	6	bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	DEPDC1 ARHGAP11A FAT1 ACAN ASPM LSS	5.22e-05	174	168	6	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANPEP MYO5B CARMIL1 PIWIL4 MISP SH3RF2	5.39e-05	175	168	6	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN MZB1 EVC SH3RF2 ERMAP FUT8	5.39e-05	175	168	6	28b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANPEP MYO5B CARMIL1 PIWIL4 MISP SH3RF2	5.39e-05	175	168	6	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PI4K2A MSANTD2 ZNF300 ARHGAP11A ZNF264 ZNF606	5.39e-05	175	168	6	87e557f7508c88b2087db5d57e77d5e2c92ca083
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-plasma_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN MZB1 EVC SH3RF2 ERMAP FUT8	5.39e-05	175	168	6	ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B SLC22A23 CARMIL1 CNTN6 CELSR1 IFT80	5.74e-05	177	168	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA5B2 PRLHR PI4K2A NALCN VPS13A ELAPOR1	5.74e-05	177	168	6	c80893e5cf5688ee9f5afc8f11b3890f296c9e1f
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a\|Striatum / BrainAtlas - Mouse McCarroll V32	F12 MISP SH3RF2 NGEF SNX31	5.84e-05	109	168	5	e8e0f2c5f8c9e45f2b4d173569c94275eedfe432
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCN1 MYO5B BCAN TFCP2L1 NGEF DIXDC1	5.92e-05	178	168	6	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCN1 MYO5B BCAN TFCP2L1 NGEF DIXDC1	5.92e-05	178	168	6	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCN1 MYO5B BCAN TFCP2L1 NGEF DIXDC1	5.92e-05	178	168	6	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCN1 MYO5B BCAN TFCP2L1 NGEF DIXDC1	5.92e-05	178	168	6	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MZB1 PIWIL1 DEPDC1 ARHGAP11A SAPCD2 ASPM	6.11e-05	179	168	6	021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANPEP TCN1 SLC22A23 BCAN GALNT13 TFCP2L1	6.11e-05	179	168	6	ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO5B PAPSS1 GALNT13 CNTN6 SH3RF2 FARP1	6.11e-05	179	168	6	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANPEP TCN1 SLC22A23 BCAN GALNT13 TFCP2L1	6.11e-05	179	168	6	c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO5B SLC22A23 GALNT13 CNTN6 CELSR1 SH3RF2	6.11e-05	179	168	6	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MZB1 TLR7 SPTBN5 NDUFAF1 MOGS ASPM	6.30e-05	180	168	6	8e96f8646c002768b272359af485dc0ab57e0ccd
Drug	BDP_X	SYNE1 CAPN1 SERPINB6 EGF ERMAP	1.04e-05	40	166	5	CID000978607
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A	SPTBN1 PI4K2A ZNF205 CHD1L CERT1 GNA13 PLCG1 ZNF606 RASAL2	1.32e-05	194	166	9	4736_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A	CRYBG2 TCN1 SPTBN1 SPTBN5 RASIP1 TFCP2L1 ARSD ZER1 RASAL2	1.32e-05	194	166	9	6031_UP
Drug	Naproxen [22204-53-1]; Down 200; 17.4uM; MCF7; HT_HG-U133A	SPTBN1 ZNF205 STAT5B VPS13A OASL PLCG1 ZNF606 EXOC7 PRODH	1.32e-05	194	166	9	5457_DN
Drug	Amiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A	KLHL24 CHRNA9 NOX5 RYR1 RASIP1 ZER1 AGBL2 EXOC7 KDM4B	1.43e-05	196	166	9	5253_UP
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	KLHL24 CRYBG2 RELN SYNE1 CHD1L GRM7 MCTP1 RASAL2 KDM4B	1.43e-05	196	166	9	6435_UP
Drug	Dioxybenzone [131-53-3]; Down 200; 16.4uM; MCF7; HT_HG-U133A	PI4K2A ZNF205 FANCC BPGM FARP1 ZER1 LSS EXOC7 MTARC1	1.55e-05	198	166	9	5699_DN
Disease	Congenital disorder of glycosylation with defective fucosylation	FCSK FUT8	3.03e-05	2	163	2	cv:C4693905
Disease	Drug habituation	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0013170
Disease	Drug abuse	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0013146
Disease	Prescription Drug Abuse	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C4316881
Disease	Substance-Related Disorders	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0236969
Disease	Drug Use Disorders	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0013222
Disease	Drug Dependence	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C1510472
Disease	Substance Dependence	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0038580
Disease	Substance Use Disorders	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0038586
Disease	Organic Mental Disorders, Substance-Induced	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.44e-05	115	163	6	C0029231
Disease	Substance abuse problem	SYNE1 PIWIL1 CHD1L GRM7 FARP1 ZNF606	4.66e-05	116	163	6	C0740858
Disease	Drug-induced agranulocytosis, response to clozapine	NFASC GRM7 TMTC3 FARP1	8.53e-05	42	163	4	GO_0097338, HP_0012235
Disease	Unipolar Depression	RELN ANPEP TLR7 GRM7 TFCP2 EGF LSAMP DIXDC1	1.02e-04	259	163	8	C0041696
Disease	neuroimaging measurement	VWA5B2 RELN ITCH CARMIL1 SPTBN1 RPL13AP3 FRYL BCAN TFCP2 ARF1 CELSR1 BPGM GNA13 SNX31 FBXL20 KDM4B	3.00e-04	1069	163	16	EFO_0004346
Disease	Major Depressive Disorder	RELN ANPEP TLR7 GRM7 TFCP2 EGF LSAMP	4.22e-04	243	163	7	C1269683
Disease	leucine-rich repeat-containing protein 15 measurement	CPNE2 B4GALNT3	6.25e-04	7	163	2	EFO_0801761
Disease	Periventricular Nodular Heterotopia	ARF1 TMTC3	6.25e-04	7	163	2	C1868720
Disease	R-warfarin measurement	SMG1 MYO5B SLC22A23 ZNF300 GRM7 ACAN ELAPOR1	7.06e-04	265	163	7	EFO_0803324
Disease	cesarean section, Self-injurious behavior	ANPEP CELSR1 LSAMP	7.30e-04	32	163	3	EFO_0009636, HP_0100716
Disease	response to topoisomerase inhibitor, response to antineoplastic agent	RPL13AP3 GRM7	1.06e-03	9	163	2	GO_0072758, GO_0097327
Disease	Autism Spectrum Disorders	RELN CHD8 NLGN4X GLRA2	1.28e-03	85	163	4	C1510586
Disease	Congenital Disorders of Glycosylation	FCSK MOGS	1.33e-03	10	163	2	C0282577
Disease	hematocrit	FOXO1 CHRNA9 RTEL1 DUSP14 SAE1 SORBS1 MCRIP1 FANCC TFCP2L1 FAT1 BPGM OASL FBXL20 FUT8	1.51e-03	1011	163	14	EFO_0004348
Disease	asparagine measurement	PIWIL4 CERT1 CNTN6	1.51e-03	41	163	3	EFO_0009766
Disease	advanced glycosylation end product-specific receptor, soluble measurement	B4GALNT3 FUT8	2.27e-03	13	163	2	EFO_0020131
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	PGS1 CERT1 ZER1 MTARC1	2.51e-03	102	163	4	EFO_0004329, EFO_0004611
Disease	Malignant neoplasm of breast	ACADM SYNE1 SORBS1 COLGALT2 ARHGAP11A CNTN6 ARF1 STAT5A EGF FARP1 ELAPOR1 NIPBL RASAL2 PRODH	2.62e-03	1074	163	14	C0006142
Disease	Crohn's disease	CUL1 SLC22A23 FERMT1 ZNF300 ADCY8 STAT5B RASIP1 SERPINB6	3.25e-03	441	163	8	EFO_0000384
Disease	severe acute respiratory syndrome, COVID-19	PGS1 RELN MYRIP NFASC GRM7 CNTN6 GLRA2 LSAMP	3.52e-03	447	163	8	EFO_0000694, MONDO_0100096
Disease	Alzheimer disease, brain volume measurement	ADCY8 FARP1	3.91e-03	17	163	2	EFO_0006930, MONDO_0004975
Disease	respiratory symptom change measurement, response to placebo	ADCY8 CNTN6	3.91e-03	17	163	2	EFO_0008344, EFO_0010068
Disease	lupus nephritis (is_marker_for)	TLR9 EGF	3.91e-03	17	163	2	DOID:0080162 (is_marker_for)
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR7 TLR9	3.91e-03	17	163	2	DOID:8677 (biomarker_via_orthology)
Disease	asthma, Eczema, allergic rhinitis	FOXO1 RTEL1 IQGAP1 RTF1	4.62e-03	121	163	4	EFO_0005854, HP_0000964, MONDO_0004979
Disease	neuroticism measurement, wellbeing measurement, depressive symptom measurement	SHISA9 FARP1	4.88e-03	19	163	2	EFO_0007006, EFO_0007660, EFO_0007869
Disease	pursuit maintenance gain measurement	SDK2 NLGN4Y CARMIL1 NGEF	4.90e-03	123	163	4	EFO_0008433
Disease	Bipolar Disorder	RELN SYNE1 GRM7 ADCY8 CNTN6 DIXDC1 PLCG1 PRODH	5.18e-03	477	163	8	C0005586

Protein segments in the cluster

Peptide	Gene	Start	Entry
GQQLEYTARLDFLWR	ADCY8	916	P40145
RLTEENGFWYLDQIR	NAT1	151	P18440
LALRWEAGIYANQEE	AKAP2	841	Q9Y2D5
AWQQFVQRGSRYRDH	C1orf167	691	Q5SNV9
EVDAALRAQLWGYTQ	ARSD	191	P51689
LREYQLEGVNWLLFN	CHD8	811	Q9HCK8
GRWIEYDRTETAINN	CPNE2	56	Q96FN4
WRAQNAVQRAAYEAL	ATG16L2	156	Q8NAA4
LIVNRYWSQFDENIR	RNF20	91	Q5VTR2
WLNQVESYIAEQRRG	B4GALNT3	561	Q6L9W6
QADVWALQLQLYRQG	APOF	101	Q13790
WSVRALVQQYEGQQR	DIXDC1	196	Q155Q3
AVRINQLYEQARWAI	FERMT1	286	Q9BQL6
DQWGQAEVLNFLLRY	AP4B1	211	Q9Y6B7
NVGFWRQLIDYERQL	DUSP14	151	O95147
VWDLRNMGYVQQRRE	BUB3	161	O43684
DERNQILTAYLWIRQ	CHRNA9	71	Q9UGM1
IRDGRQQQDYWLIDV	ANPEP	591	P15144
LDRENVAVYNLWALA	CELSR1	956	Q9NYQ6
GRSREQRYTKLADWQ	DUS3L	466	Q96G46
SYQRAAWEVDSGRRN	ACADM	336	P11310
QGAQKWVRNISYFRL	RAD54L2	771	Q9Y4B4
GLVEFNILWNRIRNY	CAPN1	606	P07384
KLGRWREESVNSNRY	C5orf52	136	A6NGY3
VQNKAASLIQGYWRR	ASPM	1346	Q8IZT6
GVSRFLQVNSAWRYD	ALG12	401	Q9BV10
GVTAAYNREQLWLAN	IQGAP1	731	P46940
YNREQLWLANEGLIT	IQGAP1	736	P46940
WGNERLVEARYQQLE	MSANTD2	116	Q6P1R3
FYQWSRAVQIRTNLD	RASIP1	796	Q5U651
LHIRSQGQWTNRLYE	NOX5	506	Q96PH1
AGASQLFRIWRYNQE	MPC2	106	O95563
YLRAQDPDHRQQWID	CERT1	96	Q9Y5P4
NNRYREYQWIGLNDR	BCAN	736	Q96GW7
VGDYWRNFQRALRNI	FAT1	3656	Q14517
NREDEGWQVYRLGAR	MISP	86	Q8IVT2
GYRRSLQESWAQNLL	C22orf46	116	C9J442
YQNRDIDQWNRTEPS	nan	891	O00370
INCINLDWINGSREY	PNLIPRP3	116	Q17RR3
WNYFLIISGKDNRQR	MCTP1	836	Q6DN14
NQVNQILSNWREERY	MED12L	1491	Q86YW9
SGNLRDRFWLVINQE	MTARC1	86	Q5VT66
HSVELNRGNNVLYWR	ELAPOR1	231	Q6UXG2
NAETVEWLRQRYDSG	FAM13B	66	Q9NYF5
VSQRSNGLRYEGEWL	JPH4	296	Q96JJ6
YDINWVRQATGQGLE	IGHV1-8	51	P0DP01
AEGLSRRAQEWYQLQ	FAT2	3486	Q9NYQ8
RRAQEWYQLQIQASD	FAT2	3491	Q9NYQ8
SRRNAWGNQSYAELI	FOXO4	96	P98177
LGQQERVQLQEYWRR	PGS1	446	Q32NB8
RTLFDWYRRQNGTED	FRYL	76	O94915
RGRQTWTYLQDERAG	LSS	31	P48449
RDTGYDWFEQLLQNL	NIPBL	1941	Q6KC79
AGEAVDWLYDLLRNN	DEPDC1	46	Q5TB30
VERTAAWVLNNGQYE	RASAL2	956	Q9UJF2
LYDDDVAQWNIGSLR	KDM4B	141	O94953
ILAYGRQQGEQDRAW	KIAA2012	116	Q0VF49
NHGEEQVRLWRRSYN	BPGM	106	P07738
ALWADSGIQNAYDRR	GNA13	151	Q14344
DSVRAQYSNWLLAGN	POGK	516	Q9P215
LLGRQAQEVRWKYQA	RPL13AP3	51	Q6NVV1
RISRWLVEYGRNQDF	EXOC7	201	Q9UPT5
YEELNVWQVNASRTR	MCM7	701	P33993
AQDYQWIGLNDRTIE	ACAN	2371	P16112
DGSIDLQANWYRIQG	RELN	1611	P78509
ELRANVVGNVWRQYQ	MOGS	786	Q13724
LNVAEGYRWDIVAQR	OASL	311	Q15646
YSLWNRDVQGALRAL	OR1K1	291	Q8NGR3
NIRWNNYIAGRAFVL	THAP12	456	O43422
GNQLWEYDAERLTLR	GALNT13	501	Q8IUC8
DYIIRNTDRGNDNWL	PI4K2A	301	Q9BTU6
LDYIIRNTDRGNDNW	PI4K2B	296	Q8TCG2
RNTDRGNDNWLVRYE	PI4K2B	301	Q8TCG2
QGARYVWNRTELLQA	ALPG	261	P10696
YGQRERVWALAQEKA	FCHSD1	151	Q86WN1
LESVRNYEQWQLQRS	ITCH	391	Q96J02
WNRVYSDTVQGQLRE	NFASC	846	O94856
NYGLLDQIQALRWIE	NLGN4Y	221	Q8NFZ3
LQVLDRVYWNDGLDQ	PAPSS1	381	O43252
VAGYLQSARAQLWRE	FCSK	296	Q8N0W3
RRNAWGNLSYADLIT	FOXO1	156	Q12778
LNRSNILYAGNDRWT	IGLON5	66	A6NGN9
ININLYNWERALELA	IFT80	691	Q9P2H3
RINSRDVWIYNSQLN	KLHL24	371	Q6TFL4
DKRLFWIQYNREGSN	EGF	211	P01133
LALWEGRSNAQIRDY	FARP1	606	Q9Y4F1
WDDLRAGIQQVYTRQ	CUL1	21	Q13616
LRSYQLEGVNWLAQR	CHD1L	46	Q86WJ1
DWSQFNTLYLRVRGD	NDUFAF1	201	Q9Y375
RSWEVSRDIYNLQQP	CRYBG2	1181	Q8N1P7
EIIGFLDQTLYRWNR	FANCC	521	Q00597
LDQTLYRWNRLGIES	FANCC	526	Q00597
YSQLDANTRNIGWRR	AGBL2	341	Q5U5Z8
LYEGLDWLSNQLRNQ	ARF1	166	P84077
IAWNRNTGRVLGYEV	CNTN6	826	Q9UQ52
DYRVNIFLRQQWNDS	GLRA2	91	P23416
IFLRQQWNDSRLAYS	GLRA2	96	P23416
ERFYESGNRANIWLV	MBLAC2	21	Q68D91
YEAWQGVERDLRGQV	MCRIP1	41	C9JLW8
GYRLIGQWTDELQLN	GRM7	491	Q14831
EVSRRSWGQQAQEYQ	CARMIL1	1326	Q5VZK9
YLRQEVQENAAWQLG	EVC	556	P57679
RLAEAVQERQQYAWL	METTL13	241	Q8N6R0
IDQAQLDWELIYIGR	COLGALT2	456	Q8IYK4
IYFWEAQRGNLTERV	SDK2	1661	Q58EX2
LLIRYVDNNRAQWLT	RYR1	3411	P21817
NYGLLDQIQALRWIE	NLGN4X	221	Q8N0W4
RDQAQAWVQYSPRVL	CCDC24	101	Q8N4L8
ALALRNWGENYDRQR	MFSD5	216	Q6N075
NWGENYDRQRAFSRT	MFSD5	221	Q6N075
RNYAGRWDVLIQQAT	HNRNPUL1	471	Q9BUJ2
GRSRAWLYLALNENS	PLEKHM2	91	Q8IWE5
QAYLVQRGAEDRDWR	OPTN	531	Q96CV9
NDNVQRELRDWGLSF	PIWIL1	431	Q96J94
TYRNVTAEQARNWGL	F12	246	P00748
NGHWLLRQSRGNEYE	ERMAP	326	Q96PL5
GTQRTLILESQNWRY	FUT8	236	Q9BYC5
FLSGQEWYRQQASRA	RTEL1	676	Q9NZ71
EWYRQQASRAVNQAI	RTEL1	681	Q9NZ71
NISAISYINQRNREW	RTF1	556	Q92541
SYINQRNREWNIVES	RTF1	561	Q92541
RYESVGWRLANQQSL	ARHGAP11A	456	Q6P4F7
RLLNIWQERSVYGGE	RPRD1B	106	Q9NQG5
GSQERQRQLYAWGLL	PRLHR	216	P49683
ALESLRQDWQAYQHR	SYNE1	3571	Q8NF91
YQNEVTGLWAQGREL	SYNE1	4506	Q8NF91
GIIDSQIRQWQRYRE	SYNE1	7556	Q8NF91
YVRETNNQALAWLDV	GIMAP6	176	Q6P9H5
WYRDDTRINSANGLE	LSAMP	251	Q13449
RAWDYGIRAGLVQNV	SLC22A23	201	A1A5C7
DGSNWQRIDLFDFQR	FBXL20	61	Q96IG2
GLYKRWQQREAALQA	SMG1	2216	Q96Q15
DSWRNLIEQIGLLYQ	NGEF	166	Q8N5V2
IQRNTNARFELETWG	PIWIL4	421	Q7Z3Z4
GNAQEAYRSRRTWEL	PRODH	56	O43272
LVLVNAVYFRGNWDE	SERPINB6	161	P35237
KLSWREQQALQVRYG	SETD6	446	Q8TBK2
WDPNEQSLRRQAYSN	SHISA9	371	B4DS77
AAQYDRQIRLWGLEA	SAE1	16	Q9UBE0
LEAWLQREAQTLQQY	STAT5B	211	P51692
QVRNQGIIALSYRDW	NSMCE4A	346	Q9NXX6
DRRLQYTEHQQLEGW	TFCP2L1	106	Q9NZI6
VRQLESLGWDNGYSR	SPATA25	96	Q9BR10
VRYSQLHGWNEQLRR	SNX31	36	Q8N9S9
ALQDQRDQVYQTWAR	SPTBN5	2026	Q9NRC6
YIREQWANLEQLSAI	SPTBN1	721	Q01082
LEAWLQREAQTLQQY	STAT5A	211	P42229
NRTLMGNWNQERYDL	C11orf1	66	Q9H5F2
GNWNQERYDLRNIVQ	C11orf1	71	Q9H5F2
NQLYLETHRGWGREQ	RINL	171	Q6ZS11
SIEDWYKNQGRILRN	ZNF564	51	Q8TBZ8
QYEGRWSVELVNDRG	TULP4	111	Q9NRJ4
QLTSRRWLNLQEYQS	SUCLG2	31	Q96I99
AIQSWDINSRRNINY	ZER1	666	Q7Z7L7
VQLLYSRVGDNWREA	VPS13A	716	Q96RL7
QRYQRGLERNDSWGS	NUFIP2	641	Q7Z417
RGRDWYQQQLQRVQE	SAPCD2	251	Q86UD0
DRRLQYTEHQQLEGW	TFCP2	126	Q12800
SAVADWVYNELRGQL	TLR9	881	Q9NR96
GERITLLRQVDENWY	SORBS1	891	Q9BX66
GLCANNNDRTYWELL	TCN1	391	P20061
GSYVVRNGENLEVRW	TCN1	416	P20061
QAGRLLWEQELYSQL	WAS	91	P42768
YQGELWAVDRLQVQE	PLCG1	261	P19174
LDVLWREGDNRYLQL	TLR7	631	Q9NYK1
EEWGQLDLAQRTLYQ	ZNF264	26	O43296
QRRDSDGDRQVWFLQ	VWA5B2	306	Q8N398
EEWGRLDHTQQNFYR	ZNF205	136	O95201
EEWGQLDAAQRTLYQ	ZNF543	21	Q08ER8
IILLRRQLDENWYQG	SH3RF2	151	Q8TEC5
IQIGYQRRNKDVLAW	TAPR1	116	Q14CZ0
WSLLSRVVAQYAQRN	TTC37	1196	Q6PGP7
STFENGNVQLWDIRR	WDR24	181	Q96S15
WRSENQNRAYVTLAA	ZBED1	201	O96006
ELDRNNADLWYNLAI	TMTC3	591	Q6ZXV5
EWQQLDPSQRTLYRD	ZNF300	21	Q96RE9
TQDAQWQRALDYLSA	PPIP5K1	861	Q6PFW1
EWGQLDLAQRTLYQE	ZNF805	26	Q5CZA5
AVNNSNYGWRALRLL	THOC1	486	Q96FV9
WGQLDLVQRTLYRDV	ZNF606	76	Q8WXB4
QEEFWIRSNNSYLRA	ZRANB3	941	Q5FWF4
AGFWQSRRNRYDLLV	NALCN	1266	Q8IZF0
ALANEGNYRELRWFT	NADSYN1	116	Q6IA69
QLRYNISQLEEWLRG	MYO5B	1711	Q9ULV0
RLLRAQSLEWFYNNV	MYRIP	111	Q8NFW9
SRNWQDYGVREVDQV	MZB1	96	Q8WU39