Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH8 DNAH9 DNAH7

6.94e-0718203GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH8 DNAH9 DNAH7

2.77e-0628203GO:0051959
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

5.71e-064202GO:0005219
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH8 DNAH9 DNAH7

6.53e-0637203GO:0045505
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

1.43e-056202GO:0048763
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH8 DNAH9 DNAH7

4.51e-0570203GO:0003777
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR3

1.44e-0418202GO:0015278
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH8 DNAH9 DNAH7

2.13e-04118203GO:0003774
GeneOntologyMolecularFunctiongated channel activity

KCNMA1 KCNV2 RYR1 RYR3

3.01e-04334204GO:0022836
GeneOntologyMolecularFunctionNADPH binding

CBR3 NOS1

3.05e-0426202GO:0070402
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNMA1 KCNV2 RYR1 RYR3

3.33e-04343204GO:0005261
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

KCNMA1 RYR1 RYR3

3.52e-04140203GO:0099094
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR3

4.36e-0431202GO:0099604
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

KCNMA1 KCNV2 RYR1

4.48e-04152203GO:0022843
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 RYR3

4.94e-0433202GO:0005217
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

KCNMA1 KCNV2 RYR1

7.57e-04182203GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

KCNMA1 KCNV2 RYR1

7.82e-04184203GO:0022832
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

KCNMA1 RYR1 RYR3

8.98e-04193203GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

KCNMA1 RYR1 RYR3

9.53e-04197203GO:0022834
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNMA1 KCNV2 RYR1 RYR3

9.97e-04459204GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

KCNMA1 KCNV2 RYR1 RYR3

1.05e-03465204GO:0046873
GeneOntologyMolecularFunctioncalmodulin binding

NOS1 RYR1 RYR3

1.49e-03230203GO:0005516
GeneOntologyMolecularFunctionchannel activity

KCNMA1 KCNV2 RYR1 RYR3

1.64e-03525204GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

KCNMA1 KCNV2 RYR1 RYR3

1.65e-03526204GO:0022803
GeneOntologyMolecularFunctionNADP binding

CBR3 NOS1

1.74e-0362202GO:0050661
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

KCNMA1 KCNV2 RYR1 RYR3

3.12e-03627204GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

KCNMA1 KCNV2 RYR1 RYR3

3.84e-03664204GO:0008324
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

KCNMA1 KCNV2

4.62e-03102202GO:0005249
GeneOntologyMolecularFunctionmonooxygenase activity

CMAHP NOS1

5.84e-03115202GO:0004497
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

KCNMA1 KCNV2 RYR1 RYR3

6.14e-03758204GO:0015318
GeneOntologyMolecularFunctionoxidoreductase activity

CMAHP CBR3 NOS1 PXDNL

6.37e-03766204GO:0016491
GeneOntologyMolecularFunctionpotassium channel activity

KCNMA1 KCNV2

7.18e-03128202GO:0005267
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

KCNMA1 KCNV2 RYR1 RYR3

7.19e-03793204GO:0015075
GeneOntologyMolecularFunctioncalcium channel activity

RYR1 RYR3

7.29e-03129202GO:0005262
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH8 DNAH9 DNAH7

9.22e-03441203GO:0016887
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

RYR1 RYR3

9.87e-03151202GO:0015085
GeneOntologyMolecularFunctionheme binding

NOS1 PXDNL

1.03e-02154202GO:0020037
GeneOntologyMolecularFunctiontetrapyrrole binding

NOS1 PXDNL

1.16e-02164202GO:0046906
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

KCNMA1 KCNV2

1.20e-02167202GO:0015079
GeneOntologyMolecularFunctiontransmembrane transporter binding

NOS1 CRBN

1.27e-02172202GO:0044325
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CMAHP NOS1

1.59e-02194202GO:0016705
GeneOntologyMolecularFunctionATP-dependent activity

DNAH8 DNAH9 DNAH7

2.23e-02614203GO:0140657
GeneOntologyBiologicalProcessmuscle contraction

KCNMA1 TMOD4 NOS1 RYR1 RYR3

3.26e-05400205GO:0006936
GeneOntologyBiologicalProcesscellular response to caffeine

RYR1 RYR3

4.89e-0511202GO:0071313
GeneOntologyBiologicalProcesscellular response to purine-containing compound

RYR1 RYR3

8.07e-0514202GO:0071415
GeneOntologyBiologicalProcesspotassium ion transport

KCNMA1 NOS1 KCNV2 CRBN

1.21e-04272204GO:0006813
GeneOntologyBiologicalProcessmuscle system process

KCNMA1 TMOD4 NOS1 RYR1 RYR3

1.44e-04547205GO:0003012
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

1.77e-04922206GO:0098662
GeneOntologyBiologicalProcessresponse to caffeine

RYR1 RYR3

1.86e-0421202GO:0031000
GeneOntologyBiologicalProcesscellular response to ATP

RYR1 RYR3

1.86e-0421202GO:0071318
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

1.99e-04942206GO:0098655
GeneOntologyBiologicalProcessresponse to alkaloid

NOS1 RYR1 RYR3

2.30e-04125203GO:0043279
GeneOntologyBiologicalProcessnegative regulation of cytosolic calcium ion concentration

NOS1 RYR3

2.64e-0425202GO:0051481
GeneOntologyBiologicalProcessmetal ion transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

2.76e-041000206GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

3.02e-041017206GO:0098660
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

NOS1 RYR1 RYR3

3.63e-04146203GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

NOS1 RYR1 RYR3

3.70e-04147203GO:0051283
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

NOS1 RYR1 RYR3

3.85e-04149203GO:0051282
GeneOntologyBiologicalProcesssequestering of calcium ion

NOS1 RYR1 RYR3

4.16e-04153203GO:0051208
GeneOntologyBiologicalProcessresponse to calcium ion

KCNMA1 RYR1 RYR3

4.83e-04161203GO:0051592
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

4.95e-041115206GO:0034220
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

RYR1 RYR3

5.83e-0437202GO:0014808
GeneOntologyBiologicalProcessmonoatomic cation transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

6.03e-041157206GO:0006812
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

RYR1 RYR3

6.48e-0439202GO:1903514
GeneOntologyBiologicalProcessresponse to ATP

RYR1 RYR3

6.82e-0440202GO:0033198
GeneOntologyBiologicalProcesscellular response to alkaloid

RYR1 RYR3

6.82e-0440202GO:0071312
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAH8 DNAH7

7.16e-0441202GO:0070286
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

RYR1 RYR3

8.25e-0444202GO:0070296
GeneOntologyBiologicalProcessnegative regulation of potassium ion transport

NOS1 CRBN

9.01e-0446202GO:0043267
GeneOntologyBiologicalProcessaction potential

KCNMA1 NOS1 KCNV2

9.20e-04201203GO:0001508
GeneOntologyBiologicalProcessregulation of muscle contraction

KCNMA1 NOS1 RYR1

9.33e-04202203GO:0006937
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAH8 DNAH9 DNAH7

1.04e-03210203GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAH8 DNAH9 DNAH7

1.12e-03215203GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAH8 DNAH9 DNAH7

1.12e-03215203GO:0001539
GeneOntologyBiologicalProcessstriated muscle contraction

NOS1 RYR1 RYR3

1.15e-03217203GO:0006941
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

NOS1 RYR1 RYR3

1.15e-03217203GO:0097553
GeneOntologyBiologicalProcessprotein homooligomerization

KCNV2 RYR1 RYR3

1.26e-03224203GO:0051260
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

KCNMA1 KCNV2 CRBN

1.39e-03232203GO:0071805
GeneOntologyBiologicalProcessmonoatomic ion transport

KCNMA1 NOS1 KCNV2 CRBN RYR1 RYR3

1.49e-031374206GO:0006811
GeneOntologyBiologicalProcessmaintenance of location in cell

NOS1 RYR1 RYR3

1.90e-03259203GO:0051651
GeneOntologyBiologicalProcesscilium movement

DNAH8 DNAH9 DNAH7

1.95e-03261203GO:0003341
GeneOntologyBiologicalProcesscalcium-mediated signaling

NOS1 RYR1 RYR3

2.06e-03266203GO:0019722
GeneOntologyBiologicalProcessvasodilation

KCNMA1 NOS1

2.19e-0372202GO:0042311
GeneOntologyBiologicalProcessprotein homotetramerization

RYR1 RYR3

2.50e-0377202GO:0051289
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

KCNMA1 NOS1 RYR1 RYR3

2.53e-03611204GO:0030003
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

KCNMA1 NOS1 RYR1 RYR3

2.70e-03622204GO:0006873
GeneOntologyBiologicalProcessinorganic ion homeostasis

KCNMA1 NOS1 RYR1 RYR3

2.70e-03622204GO:0098771
GeneOntologyBiologicalProcessprotein complex oligomerization

KCNV2 RYR1 RYR3

2.78e-03296203GO:0051259
GeneOntologyBiologicalProcesscellular response to calcium ion

RYR1 RYR3

3.25e-0388202GO:0071277
GeneOntologyBiologicalProcessregulation of muscle system process

KCNMA1 NOS1 RYR1

3.38e-03317203GO:0090257
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

KCNMA1 NOS1 RYR1 RYR3

4.24e-03705204GO:0055080
GeneOntologyBiologicalProcessresponse to estrogen

KCNMA1 NOS1

4.42e-03103202GO:0043627
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

KCNMA1 NOS1 RYR1 RYR3

4.50e-03717204GO:0050801
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

NOS1 RYR1 RYR3

4.78e-03359203GO:0006874
GeneOntologyBiologicalProcessaxoneme assembly

DNAH8 DNAH7

4.94e-03109202GO:0035082
GeneOntologyBiologicalProcessresponse to osmotic stress

KCNMA1 RYR1

5.30e-03113202GO:0006970
GeneOntologyBiologicalProcessprotein tetramerization

RYR1 RYR3

5.30e-03113202GO:0051262
GeneOntologyBiologicalProcessnegative regulation of cation transmembrane transport

NOS1 CRBN

5.58e-03116202GO:1904063
GeneOntologyBiologicalProcesscalcium ion homeostasis

NOS1 RYR1 RYR3

5.98e-03389203GO:0055074
GeneOntologyBiologicalProcessregulation of potassium ion transport

NOS1 CRBN

6.05e-03121202GO:0043266
GeneOntologyBiologicalProcessstriated muscle cell differentiation

TMOD4 NOS1 RYR1

6.06e-03391203GO:0051146
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

NOS1 RYR1 RYR3

6.11e-03392203GO:0070588
GeneOntologyBiologicalProcessmaintenance of location

NOS1 RYR1 RYR3

6.28e-03396203GO:0051235
GeneOntologyBiologicalProcessnegative regulation of monoatomic ion transmembrane transport

NOS1 CRBN

6.35e-03124202GO:0034766
GeneOntologyCellularComponentaxonemal dynein complex

DNAH8 DNAH9 DNAH7

1.70e-0625203GO:0005858
GeneOntologyCellularComponentsarcoplasm

KCNMA1 NOS1 RYR1 RYR3

3.80e-06114204GO:0016528
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

NOS1 RYR1 RYR3

1.04e-0545203GO:0033017
GeneOntologyCellularComponentdynein complex

DNAH8 DNAH9 DNAH7

1.80e-0554203GO:0030286
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

3.12e-059202GO:0030314
GeneOntologyCellularComponentouter dynein arm

DNAH8 DNAH9

5.71e-0512202GO:0036157
GeneOntologyCellularComponentcation channel complex

KCNMA1 KCNV2 RYR1 RYR3

6.55e-05235204GO:0034703
GeneOntologyCellularComponentsupramolecular fiber

TMOD4 DNAH8 DNAH9 NOS1 DNAH7 RYR1 RYR3

7.22e-051179207GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

TMOD4 DNAH8 DNAH9 NOS1 DNAH7 RYR1 RYR3

7.53e-051187207GO:0099081
GeneOntologyCellularComponentsarcoplasmic reticulum

NOS1 RYR1 RYR3

7.80e-0588203GO:0016529
GeneOntologyCellularComponentsarcomere

TMOD4 NOS1 RYR1 RYR3

8.19e-05249204GO:0030017
GeneOntologyCellularComponentmyofibril

TMOD4 NOS1 RYR1 RYR3

1.17e-04273204GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

TMOD4 NOS1 RYR1 RYR3

1.48e-04290204GO:0043292
GeneOntologyCellularComponentZ disc

NOS1 RYR1 RYR3

3.85e-04151203GO:0030018
GeneOntologyCellularComponentmonoatomic ion channel complex

KCNMA1 KCNV2 RYR1 RYR3

4.05e-04378204GO:0034702
GeneOntologyCellularComponentmicrotubule associated complex

DNAH8 DNAH9 DNAH7

4.64e-04161203GO:0005875
GeneOntologyCellularComponentI band

NOS1 RYR1 RYR3

5.08e-04166203GO:0031674
GeneOntologyCellularComponentsarcolemma

NOS1 RYR1 RYR3

7.52e-04190203GO:0042383
GeneOntologyCellularComponentsmooth endoplasmic reticulum

RYR1 RYR3

8.78e-0446202GO:0005790
GeneOntologyCellularComponentaxoneme

DNAH8 DNAH9 DNAH7

9.63e-04207203GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH8 DNAH9 DNAH7

9.77e-04208203GO:0097014
GeneOntologyCellularComponenttransmembrane transporter complex

KCNMA1 KCNV2 RYR1 RYR3

1.36e-03523204GO:1902495
GeneOntologyCellularComponent9+2 motile cilium

DNAH8 DNAH9 DNAH7

1.44e-03238203GO:0097729
GeneOntologyCellularComponentperinuclear region of cytoplasm

KCNMA1 NOS1 CRBN RYR1 RYR3

1.56e-03934205GO:0048471
GeneOntologyCellularComponenttransporter complex

KCNMA1 KCNV2 RYR1 RYR3

1.64e-03550204GO:1990351
GeneOntologyCellularComponentcalcium channel complex

RYR1 RYR3

2.19e-0373202GO:0034704
GeneOntologyCellularComponentT-tubule

NOS1 RYR1

2.56e-0379202GO:0030315
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH8 DNAH9 DNAH7

3.25e-03317203GO:0032838
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNMA1 KCNV2

3.38e-0391202GO:0008076
GeneOntologyCellularComponentpotassium channel complex

KCNMA1 KCNV2

4.39e-03104202GO:0034705
GeneOntologyCellularComponentmotile cilium

DNAH8 DNAH9 DNAH7

4.47e-03355203GO:0031514
GeneOntologyCellularComponentcytoplasmic region

DNAH8 DNAH9 DNAH7

4.65e-03360203GO:0099568
GeneOntologyCellularComponentcaveola

KCNMA1 NOS1

4.99e-03111202GO:0005901
GeneOntologyCellularComponentplasma membrane raft

KCNMA1 NOS1

8.59e-03147202GO:0044853
GeneOntologyCellularComponentazurophil granule

NOS1 FUCA2

1.01e-02160202GO:0042582
GeneOntologyCellularComponentprimary lysosome

NOS1 FUCA2

1.01e-02160202GO:0005766
GeneOntologyCellularComponentmembrane protein complex

KCNMA1 KCNV2 LRRN3 RYR1 RYR3

1.17e-021498205GO:0098796
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

RYR1 RYR3

1.33e-02185202GO:0009898
GeneOntologyCellularComponentmicrotubule

DNAH8 DNAH9 DNAH7

1.36e-02533203GO:0005874
GeneOntologyCellularComponentaxon terminus

KCNMA1 NOS1

1.69e-02210202GO:0043679
MousePhenoabnormal muscle relaxation

KCNMA1 NOS1 RYR1

5.15e-0561173MP:0004036
DomainDynein_heavy_dom-2

DNAH8 DNAH9 DNAH7

3.23e-0714193IPR013602
DomainDynein_heavy_chain_D4_dom

DNAH8 DNAH9 DNAH7

3.23e-0714193IPR024317
DomainDHC_N2

DNAH8 DNAH9 DNAH7

3.23e-0714193PF08393
DomainMT

DNAH8 DNAH9 DNAH7

3.23e-0714193PF12777
DomainAAA_8

DNAH8 DNAH9 DNAH7

3.23e-0714193PF12780
DomainDynein_HC_stalk

DNAH8 DNAH9 DNAH7

3.23e-0714193IPR024743
DomainDHC_fam

DNAH8 DNAH9 DNAH7

4.03e-0715193IPR026983
DomainDynein_heavy_dom

DNAH8 DNAH9 DNAH7

4.03e-0715193IPR004273
DomainDynein_heavy

DNAH8 DNAH9 DNAH7

4.03e-0715193PF03028
DomainRR_TM4-6

RYR1 RYR3

2.94e-063192PF06459
DomainRyanrecept_TM4-6

RYR1 RYR3

2.94e-063192IPR009460
DomainRyR

RYR1 RYR3

2.94e-063192PF02026
DomainRyanodine_rcpt

RYR1 RYR3

2.94e-063192IPR003032
DomainRyan_recept

RYR1 RYR3

2.94e-063192IPR013333
DomainIon_trans_dom

KCNMA1 KCNV2 RYR1 RYR3

4.75e-06114194IPR005821
DomainIon_trans

KCNMA1 KCNV2 RYR1 RYR3

4.75e-06114194PF00520
DomainRIH_assoc

RYR1 RYR3

1.47e-056192PF08454
DomainRIH_assoc-dom

RYR1 RYR3

1.47e-056192IPR013662
DomainIns145_P3_rec

RYR1 RYR3

1.47e-056192PF08709
DomainRYDR_ITPR

RYR1 RYR3

1.47e-056192PF01365
DomainRIH_dom

RYR1 RYR3

1.47e-056192IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3

1.47e-056192IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3

1.47e-056192IPR015925
Domain-

RYR1 RYR3

1.47e-0561921.25.10.30
DomainDynein_heavy_dom-1

DNAH8 DNAH9

2.74e-058192IPR013594
DomainDHC_N1

DNAH8 DNAH9

2.74e-058192PF08385
DomainMIR

RYR1 RYR3

4.39e-0510192PS50919
DomainMIR

RYR1 RYR3

4.39e-0510192PF02815
DomainMIR

RYR1 RYR3

4.39e-0510192SM00472
DomainMIR_motif

RYR1 RYR3

4.39e-0510192IPR016093
DomainATPase_dyneun-rel_AAA

DNAH8 DNAH9

8.86e-0514192IPR011704
DomainAAA_5

DNAH8 DNAH9

8.86e-0514192PF07728
DomainSPRY

TRIM43B RYR1 RYR3

8.96e-0587193SM00449
DomainSPRY

TRIM43B RYR1 RYR3

1.13e-0494193PF00622
DomainSPRY_dom

TRIM43B RYR1 RYR3

1.13e-0494193IPR003877
DomainB30.2/SPRY

TRIM43B RYR1 RYR3

1.16e-0495193IPR001870
DomainB302_SPRY

TRIM43B RYR1 RYR3

1.16e-0495193PS50188
DomainAAA+_ATPase

DNAH8 DNAH9 DNAH7

3.97e-04144193IPR003593
DomainAAA

DNAH8 DNAH9 DNAH7

3.97e-04144193SM00382
DomainVG_K_chnl

KCNMA1 KCNV2

5.08e-0433192IPR028325
DomainConA-like_dom

TRIM43B RYR1 RYR3

1.34e-03219193IPR013320
DomainEF_hand_dom

DNAH7 RYR1 RYR3

1.58e-03232193IPR002048
DomainCys-rich_flank_reg_C

PXDNL LRRN3

3.72e-0390192IPR000483
DomainLRRCT

PXDNL LRRN3

3.72e-0390192SM00082
Domain-

TMOD4 PXDNL LRRN3

3.97e-033211933.80.10.10
DomainL_dom-like

TMOD4 PXDNL LRRN3

4.22e-03328193IPR032675
DomainLRRNT

PXDNL LRRN3

4.40e-0398192IPR000372
DomainLRRNT

PXDNL LRRN3

4.40e-0398192SM00013
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH8 DNAH9 DNAH7

2.25e-0627143M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH8 DNAH9 DNAH7

9.40e-0643143M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH8 DNAH9 DNAH7

1.08e-0545143M47670
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

NOS1 RYR1 GPR182 RYR3

1.26e-05154144MM15974
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

NOS1 RYR1 GPR182 RYR3

1.32e-05156144M39475
PathwayREACTOME_MUSCLE_CONTRACTION

TMOD4 NOS1 RYR1 RYR3

1.65e-05165144MM15026
PathwayREACTOME_ION_HOMEOSTASIS

NOS1 RYR1 RYR3

1.88e-0554143M27460
PathwayREACTOME_ION_HOMEOSTASIS

NOS1 RYR1 RYR3

1.88e-0554143MM15202
PathwayREACTOME_MUSCLE_CONTRACTION

TMOD4 NOS1 RYR1 RYR3

3.73e-05203144M5485
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 RYR3

5.01e-0511142M47958
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR3

7.10e-0513142M39589
PathwayREACTOME_CARDIAC_CONDUCTION

NOS1 RYR1 RYR3

1.30e-04103143MM15196
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR3

1.55e-0419142M47760
PathwayREACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE

KCNMA1 NOS1

2.09e-0422142M915
PathwayREACTOME_CARDIAC_CONDUCTION

NOS1 RYR1 RYR3

2.59e-04130143M27454
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

NOS1 RYR1 RYR3

6.50e-04178143M2890
PathwayKEGG_LONG_TERM_DEPRESSION

NOS1 RYR1

2.13e-0370142M8232
PathwayWP_ALZHEIMERS_DISEASE

NOS1 RYR3

2.37e-0374142MM15962
PathwayREACTOME_PLATELET_HOMEOSTASIS

KCNMA1 NOS1

3.19e-0386142M916
PathwayREACTOME_STIMULI_SENSING_CHANNELS

RYR1 RYR3

4.21e-0399142MM14910
PathwayREACTOME_POTASSIUM_CHANNELS

KCNMA1 KCNV2

4.54e-03103142M1073
PathwayREACTOME_STIMULI_SENSING_CHANNELS

RYR1 RYR3

4.81e-03106142M27200
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

RYR1 RYR3

9.05e-03147142MM15854
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

RYR1 RYR3

9.53e-03151142M39329
PathwayKEGG_ALZHEIMERS_DISEASE

NOS1 RYR3

1.14e-02166142M16024
PathwayREACTOME_ION_CHANNEL_TRANSPORT

RYR1 RYR3

1.28e-02176142MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

RYR1 RYR3

1.38e-02183142M997
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

3.14e-07220212565913
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

3.14e-0722029489997
Pubmed

Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells.

KCNMA1 RYR1

3.14e-07220219096717
Pubmed

Temporal and spatial mouse brain expression of cereblon, an ionic channel regulator involved in human intelligence.

KCNMA1 CRBN

3.14e-07220220131966
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

3.14e-07220215894801
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

3.14e-0722029192302
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

3.14e-07220212640042
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

3.14e-0722027556644
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

3.14e-07220214592949
Pubmed

Variable phenotype of del45-55 Becker patients correlated with nNOSμ mislocalization and RYR1 hypernitrosylation.

NOS1 RYR1

3.14e-07220222589245
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

3.14e-0722029799464
Pubmed

Dysregulation of large-conductance Ca2+-activated K+ channel expression in nonsyndromal mental retardation due to a cereblon p.R419X mutation.

KCNMA1 CRBN

3.14e-07220218414909
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

3.14e-07220217118445
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

3.14e-0722029817784
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

3.14e-07220211500519
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR3

9.42e-07320225239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR3

9.42e-0732027621815
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR3

9.42e-0732029204703
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR3

9.42e-07320218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR3

9.42e-07320211159936
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR3

9.42e-0732027876312
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR3

9.42e-0732029242641
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR3

9.42e-07320218403125
Pubmed

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

RYR1 RYR3

9.42e-07320211171121
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR3

9.42e-07320221881589
Pubmed

Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.

RYR1 RYR3

9.42e-07320218313230
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR3

9.42e-07320222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR3

9.42e-07320210788707
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR3

9.42e-07320218434746
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR3

9.42e-07320210473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR3

9.42e-0732027959768
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR3

9.42e-07320212213830
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR3

9.42e-0732024600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR3

9.42e-0732027635066
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR1 RYR3

1.88e-06420222100703
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR3

1.88e-0642029384575
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR3

1.88e-06420218206662
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR3

1.88e-0642029607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR3

1.88e-06420223482488
Pubmed

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.

NOS1 RYR1

1.88e-06420232693782
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR3

1.88e-06420223413940
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR3

3.14e-06520219011160
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR1 RYR3

3.14e-06520223918386
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR1 RYR3

4.71e-06620219549818
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR1 RYR3

4.71e-06620219009018
Pubmed

Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.

RYR1 RYR3

4.71e-06620210444070
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR3

4.71e-06620216844763
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR1 RYR3

4.71e-06620226025922
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR1 RYR3

4.71e-06620214592808
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR3

4.71e-06620223463619
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR3

4.71e-06620220519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR3

4.71e-06620225966694
Pubmed

CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory.

KCNMA1 CRBN

4.71e-06620229370161
Pubmed

Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression.

TMOD4 NOS1 CPT1B

4.92e-065820321884692
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH8 DNAH9

6.59e-06720231178125
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR1 RYR3

6.59e-06720220962236
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR3

6.59e-06720211860456
Pubmed

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

RYR1 RYR3

8.78e-06820230563862
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR1 RYR3

8.78e-06820211784029
Pubmed

Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.

RYR1 RYR3

8.78e-06820221441923
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR3

8.78e-06820219033399
Pubmed

Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy.

RYR1 RYR3

1.13e-05920221858002
Pubmed

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.

DNAH9 DNAH7

1.72e-051120224421334
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR1 RYR3

2.07e-051220219095005
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH8 DNAH7

2.85e-05142029373155
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

KCNMA1 RYR1 RYR3

7.37e-0514320320424473
Pubmed

Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.

RYR1 RHBDL2

1.35e-043020220080650
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

RYR1 RYR3

2.18e-043820230786075
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH8 DNAH9

3.34e-04472028812413
GeneFamilyDyneins, axonemal

DNAH8 DNAH9 DNAH7

3.12e-0717153536
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

1.93e-063152287
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PXDNL LRRN3

7.67e-03161152593
GeneFamilyEF-hand domain containing

DNAH7 RYR3

1.38e-02219152863
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DNAH9 KCNV2 RYR3

7.14e-07160204c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DNAH9 KCNV2 RYR3

7.14e-0716020425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Ptgfr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DNAH9 RYR1 RYR3

2.42e-05127203fb58f4b4d3722f4b9a2e4946c0244c5b70dd883b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CBR3 NOS1 RYR1

2.71e-05132203ddebc0b233fdbb73ceb70187945bbed8fd273f2a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TMOD4 DNAH9 NOS1

3.03e-051372035cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNAH9 RYR1 RYR3

3.52e-0514420308005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellCOVID-19-kidney-Technical/muscle|kidney / Disease (COVID-19 only), tissue and cell type

DNAH8 DNAH9 NOS1

3.82e-051482030dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCell368C-Fibroblasts-Fibroblast-F|368C / Donor, Lineage, Cell class and subclass (all cells)

CBR3 DNAH7 PXDNL

4.55e-0515720374038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell368C-Fibroblasts-Fibroblast-F-|368C / Donor, Lineage, Cell class and subclass (all cells)

CBR3 DNAH7 PXDNL

4.55e-05157203982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM43B LRRN3 RYR3

4.72e-051592034000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH8 DNAH9 RYR1

4.72e-051592035335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM43B LRRN3 RYR3

4.72e-051592037619d0d49738dd08daf01b42664691a5323aa793
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KCNMA1 RYR3 CPT1B

5.09e-051632031e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM43B LRRN3 RYR3

5.37e-051662035e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRIM43B LRRN3 RYR3

5.37e-05166203bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMAHP RYR3 CPT1B

5.66e-05169203d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMAHP RYR3 CPT1B

5.66e-05169203befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMOD4 DNAH9 RYR3

5.66e-0516920312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KCNMA1 CBR3 RAI2

6.50e-0517720399500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH9 DNAH7 CPT1B

6.61e-051782033b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KCNMA1 PXDNL RYR3

8.02e-05190203938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

DNAH9 DNAH7 RYR3

8.14e-051912036228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

DNAH9 DNAH7 RYR3

8.14e-05191203ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM43B GPR182 RAI2

8.27e-051922030b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAH9 NOS1 RYR3

8.66e-0519520319853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAH9 NOS1 RYR3

8.66e-05195203d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

KCNMA1 PXDNL LRRN3

8.79e-0519620324d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

CMAHP DNAH9 DNAH7

8.79e-05196203af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

CMAHP DNAH9 DNAH7

8.79e-051962036d02d494196e3f857d53eea46d9419690d43beca
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

KCNMA1 NOS1 RYR1

8.92e-0519720315b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

KCNMA1 NOS1 RYR1

8.92e-05197203a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellBronchus_Control_(B.)-Epithelial-TX-Transitional_AT2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

KCNMA1 TMOD4 RHBDL2

9.19e-05199203cd581d7330b471431ef427f8a4f5be553f70e068
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)--|Striatum / BrainAtlas - Mouse McCarroll V32

TMOD4 NOS1

5.38e-04772027bb18406d404c51ee938cc577c155dc51868ddb9
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)|Striatum / BrainAtlas - Mouse McCarroll V32

TMOD4 NOS1

5.38e-0477202ac311740424ff75b478b3c19fa0fae93776eb54e
ToppCellStriatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)-|Striatum / BrainAtlas - Mouse McCarroll V32

TMOD4 NOS1

5.38e-04772029f2dbf922acb905d636427a766a217c0db9671d2
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Chodl_(MGE-derived_cortical_interneurons--Long-range-projecting_interneurons)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

DNAH9 NOS1

5.81e-04802021f022bd04de842ec7193e98acae0df17913f4749
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Chodl_(MGE-derived_cortical_interneurons--Long-range-projecting_interneurons)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

DNAH9 NOS1

5.81e-0480202f102890f86fffb30d180a2450b71581181c803cf
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Npsr1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DNAH9 RYR1

5.96e-04812025d9b08bc1ae6ecb894c88c9784fdc4203682d087
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-5|TCGA-Breast / Sample_Type by Project: Shred V9

RYR1 FUCA2

9.23e-04101202f4db710b2510cdbee26dd5c3b581c85fe6f0be00
ToppCellCOVID-19-Heart-Fib_+_CM|Heart / Disease (COVID-19 only), tissue and cell type

NOS1 RYR1

9.79e-041042020b60a56a46f1fe3f8224ec6399d009a34a117a21
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Thalamus / BrainAtlas - Mouse McCarroll V32

CMAHP CPT1B

1.11e-03111202567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Thalamus / BrainAtlas - Mouse McCarroll V32

CMAHP CPT1B

1.11e-03111202d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Thalamus / BrainAtlas - Mouse McCarroll V32

CMAHP CPT1B

1.11e-03111202fd7aa25e83a0d762969e3966a658652da40c490e
ToppCellThalamus-Hematopoietic-MACROPHAGE|Thalamus / BrainAtlas - Mouse McCarroll V32

CMAHP CPT1B

1.11e-03111202d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Thalamus / BrainAtlas - Mouse McCarroll V32

CMAHP CPT1B

1.11e-03111202a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCell(05)_Ciliated-(3)_72hpi|(05)_Ciliated / shred by cell type and Timepoint

DNAH8 CPT1B

1.15e-03113202eaa5bc8f8183b353ee1e7618e99220eb3684cd60
ToppCellControl-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

KCNMA1 DNAH8

1.39e-031242023e987915026f503e8d072a837b6e7a34252e5c63
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Hpgd|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RYR1 RYR3

1.43e-031262029b04ca8a46cc30119baf6ef27711a0b2a6b4a0c9
ToppCellURO-Lymphocyte-T_NK-CD8_Naive|URO / Disease, Lineage and Cell Type

NOS1 LRRN3

1.62e-03134202142b7db0c2b686c8f2704ff7bcd9b44dfcb07403
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

DNAH7 RYR1

1.62e-031342022647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RYR1 RYR3

1.62e-03134202cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CMAHP GPR182

1.64e-031352024cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

CMAHP GPR182

1.64e-031352026bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

CMAHP GPR182

1.64e-031352027e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CMAHP GPR182

1.64e-0313520297989546826bf3739e1b86a10832a457fd37c5d2
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-7|TCGA-Stomach / Sample_Type by Project: Shred V9

KCNMA1 RYR3

1.64e-03135202451e90c154e26ae4f72269d6765e7ef51d67313a
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RYR1 RYR3

1.66e-031362021f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TMOD4 LRRN3

1.69e-031372029bfdbc102cdd861996b3c4eac35b606be8af97eb
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH8 NOS1

1.74e-0313920213247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH8 CPT1B

1.76e-03140202af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RYR1 RYR3

1.76e-031402027cc891d676555609add6fc7880735d948a2ad801
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2|TCGA-Bladder / Sample_Type by Project: Shred V9

KCNMA1 RYR3

1.79e-031412021baa054c2ae3b446d1954244b7fbf8af824ef345
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DNAH9

1.79e-031412024aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DNAH9

1.79e-03141202e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NOS1 RYR1

1.86e-03144202f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DNAH9 NOS1

1.86e-03144202b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NOS1 KCNV2

1.89e-0314520278f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c4-DNAJB1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KCNMA1 RAI2

1.96e-03148202e73860f6b8021482f82b83ccd2b7e1dfd7d9e80b
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH8 DNAH7

1.96e-031482026ffa212f0cc44c40d2143816dc6cfd82fbf09a33
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CBR3 RYR1

1.96e-03148202d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

1.96e-03148202d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

1.96e-03148202c8e93b87212f55774223caa385859c566fa1981f
ToppCell368C-Fibroblasts-Fibroblast-F-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DNAH7 PXDNL

1.99e-031492029286bc56ff2e245630537a0bda5f1a1e17be863a
ToppCell368C-Fibroblasts-Fibroblast-F|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DNAH7 PXDNL

1.99e-03149202f53151d9e5e724a61be0ee6a8c740d1990f28d5f
ToppCellSerous|World / shred by cell class for turbinate

KCNMA1 CBR3

2.02e-031502026a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH8 RYR1

2.02e-031502020205318a870e091add66ee4305747dda9f51510d
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH8 CPT1B

2.02e-0315020253de595376a9fc92491dfd58ff25938b0bf79903
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CMAHP NOS1

2.02e-03150202cc8361bdcaa16ab6a0d6a3684690d709bc42ff3b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH8 CPT1B

2.02e-03150202e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH9 DNAH7

2.04e-031512029d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAH9 DNAH7

2.04e-031512028216462e723fec2797387929dde095370947e10a
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBR3 RYR1

2.07e-0315220282a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellURO-Lymphocyte-T_NK-CD4_Naive|URO / Disease, Lineage and Cell Type

NOS1 LRRN3

2.12e-031542026c214ad5cbbfa8bab3f76b593cb598dfb914b566
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

2.12e-031542024e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

2.12e-031542027556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

2.12e-0315420258072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

2.12e-031542029ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellileum-BEST4+_Enterocytes|ileum / shred on tissue and cell subclass

CMAHP RAI2

2.12e-03154202608e9c982125e0c2c15b86b1920813845a0db81f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDL2 CPT1B

2.12e-0315420266c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

NOS1 RYR1

2.15e-03155202d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

2.15e-031552025f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH9 DNAH7

2.15e-031552020944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Tregs|GI_small-bowel / Manually curated celltypes from each tissue

DNAH8 RYR1

2.15e-03155202d4ef25965a15eab7679478b9b661e1b4a92f1c59
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CMAHP NOS1

2.18e-031562026f8622716bad4e505f241a2a4ef953bf3fc6dbfa
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CBR3 RYR1

2.18e-031562022cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR3 CPT1B

2.21e-031572029021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellcontrol-B_cell|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CBR3 RHBDL2

2.21e-031572021269b55f2ef6a493f6116b131cc5cc7b8897d63e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHBDL2 CPT1B

2.21e-03157202b527e88382c8d21188a0f222b3302523e8816dfc
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR3 CPT1B

2.21e-03157202c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellCOVID-19-APC-like-Monocytes|COVID-19 / group, cell type (main and fine annotations)

LRRN3 RYR1

2.23e-03158202a0d94bd067424783863a48db20976d4c2043600c
ComputationalGenes in the cancer module 330.

NOS1 RYR1

3.55e-0428112MODULE_330
ComputationalMuscle genes.

NOS1 RYR1

6.22e-0437112MODULE_512
ComputationalGenes in the cancer module 387.

NOS1 RYR1

1.09e-0349112MODULE_387
ComputationalGenes in the cancer module 201.

NOS1 RYR1

1.14e-0350112MODULE_201
ComputationalGenes in the cancer module 329.

NOS1 RYR1

1.18e-0351112MODULE_329
Drugcaged InsP3

KCNMA1 RYR1 RYR3 CPT1B

1.01e-0829204CID000122248
DrugMBED

KCNMA1 RYR1 RYR3

1.16e-086203CID000129958
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

7.33e-072202ctd:C005147
DrugAC1O3MDH

NOS1 RYR1 GPR182 RYR3

1.74e-06102204CID006332158
DrugS-nitrosoacetylcysteine

KCNMA1 NOS1 RYR1

2.09e-0629203CID000122058
Drug2-hydroxyheptanoic acid

RYR1 RYR3

2.20e-063202CID002750949
Drugflubendiamide

RYR1 RYR3

2.20e-063202CID011193251
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR3

2.20e-063202CID005748312
Drug8N3-cADPR

RYR1 RYR3

2.20e-063202CID000127713
Drug2-hydroxycarbazole

RYR1 RYR3

2.20e-063202CID000093551
Drugaminodantrolene

RYR1 RYR3

2.20e-063202CID009570289
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

2.20e-063202CID000080262
Drugcis-diammineplatinum(II

RYR1 RYR3

2.20e-063202CID000159790
DrugA-30

RYR1 RYR3

4.39e-064202CID003028528
DrugBastadin 10

RYR1 RYR3

4.39e-064202CID009589366
DrugSC 38249

RYR1 RYR3

4.39e-064202CID000134834
DrugAC1L1U7A

RYR1 RYR3

4.39e-064202CID000035682
DrugPCB74

RYR1 RYR3

4.39e-064202CID000036218
Drug148504-47-6

RYR1 RYR3

4.39e-064202CID006444275
DrugAC1L1IZE

DNAH8 DNAH9 RYR1 RYR3

4.72e-06131204CID000004799
Drugebselen

KCNMA1 NOS1 RYR1 RYR3

4.72e-06131204CID000003194
DrugCsCl

KCNMA1 RYR1 RHBDL2 RYR3

5.48e-06136204CID000024293
Drugisocitrate

KCNMA1 RYR1 RYR3 CPT1B

9.43e-06156204CID000001198
DrugAC1O528X

RYR1 RYR3

1.10e-056202CID006475857
DrugNSC114784

RYR1 RYR3

1.10e-056202CID000419425
DrugNSC692750

RYR1 RYR3

1.10e-056202CID000078910
Drugchloro-m-cresol

RYR1 RYR3

1.10e-056202CID000012008
Drugetridiazole

KCNMA1 RYR1 RYR3

1.11e-0550203CID000017432
DrugNor 3

KCNMA1 NOS1 RYR1

1.11e-0550203CID009578441
DrugAC1L1KRB

RYR1 GPR182 RYR3

1.40e-0554203CID000005621
DrugAzumoleno

RYR1 RYR3

1.54e-057202CID000056259
Drugmag-indo-1

RYR1 RYR3

1.54e-057202CID000131881
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR3

1.54e-057202CID009547999
DrugCHEBI:564108

RYR1 RYR3

1.54e-057202CID006400637
DrugBr2BAPTA

RYR1 RYR3

1.54e-057202CID003081001
DrugHMS3267E16

RYR1 GPR182 RYR3

2.12e-0562203CID000003668
Druglactosyl lysosphingolipid

RYR1 RYR3

2.63e-059202CID006439268
DrugFLA 365

RYR1 RYR3

2.63e-059202CID000072776
DrugAC1N38XE

RYR1 RYR3

3.28e-0510202CID004060965
DrugPCB 95

RYR1 RYR3

3.28e-0510202CID000038012
DrugR 478

RYR1 RYR3

4.01e-0511202CID000084223
Drug8-amino-cADPR

RYR1 RYR3

4.01e-0511202CID003081323
DrugPCB 66

RYR1 RYR3

4.01e-0511202CID000036185
Drugcarbanilide

KCNMA1 RYR1

4.01e-0511202CID000007595
DrugRyanodine

RYR1 RYR3

4.81e-0512202ctd:D012433
Drugverapamil

KCNMA1 NOS1 KCNV2 RYR1 RYR3

5.37e-05490205CID000002520
DrugNSC299933

RYR1 RYR3

5.68e-0513202CID000431902
Drugcromakalim

KCNMA1 NOS1 CPT1B

6.06e-0588203CID000071191
Drugbimoclomol

RYR1 RYR3

6.63e-0514202CID009576891
DrugCID6426996

KCNMA1 CPT1B

6.63e-0514202CID006426996
DrugNP-EGTA

RYR1 RYR3

6.63e-0514202CID000183793
Drugsodium nitroprusside

KCNMA1 NOS1 RYR1 RYR3

7.08e-05261204CID000045469
DrugFPL 64176

RYR1 RYR3

7.64e-0515202CID000003423
DrugGvapspat amide

RYR1 RYR3

7.64e-0515202CID000125015
Drugisotetrandrine

KCNMA1 RYR1 RYR3

8.11e-0597203CID000005422
DrugAC1L1KC5

KCNMA1 NOS1 RYR1 GPR182 RYR3

8.58e-05541205CID000005428
Drugindo-1

KCNMA1 RYR1 RYR3

8.62e-0599203CID000105060
Drugrilmakalim

KCNMA1 CPT1B

8.73e-0516202CID000065966
DrugDM-nitrophen

RYR1 RYR3

8.73e-0516202CID000003083
Drugmagnesium

KCNMA1 DNAH8 DNAH9 NOS1 RYR1 RYR3 CPT1B

8.81e-051325207CID000000888
Drugisradipine

KCNMA1 RYR1 RYR3

8.88e-05100203CID000003784
Drugisoflurane

KCNMA1 NOS1 RYR1 RYR3

9.16e-05279204CID000003763
Drugkazinol B

RYR1 RYR3

9.89e-0517202CID000480869
DrugU46619

NOS1 RYR1 GPR182 RYR3

9.94e-05285204CID000005618
Drugsevoflurane

RYR1 RYR3 CPT1B

1.03e-04105203CID000005206
DrugK-Cl

KCNMA1 NOS1 RYR1 RYR3 CPT1B

1.07e-04567205CID000004873
Drugphosphine oxide

KCNMA1 RYR1 RYR3

1.09e-04107203CID000166931
Drugmethylcoumarin

RYR1 RYR3

1.11e-0418202CID000007092
Drugguanosine 3',5'-cyclic monophosphoric acid

KCNMA1 DNAH9 NOS1 RYR1 RYR3

1.16e-04577205CID000000295
DrugAC1L380G

RYR1 RYR3

1.24e-0419202CID000084698
DrugAC1MW7VF

RYR1 RYR3

1.24e-0419202CID000414699
DrugSK&F 82958

NOS1 RYR1

1.24e-0419202ctd:C071262
DrugAC1L1IZ2

KCNMA1 DNAH9 RYR1 RYR3

1.28e-04304204CID000004795
DrugAC1L1KF5

NOS1 RYR1 RYR3

1.28e-04113203CID000005470
Drug8-bromoguanosine 3',5'-cyclic monophosphate

KCNMA1 NOS1 RYR1 RYR3

1.34e-04308204CID000001915
Drughalothane

KCNMA1 NOS1 RYR1 RYR3

1.44e-04314204CID000003562
DrugTCNB

TMOD4 RYR1 RYR3

1.49e-04119203CID000008330
Drugindo-1/AM

RYR1 RYR3

1.52e-0421202CID000123918
DrugAC1L1CR9

RYR1 RYR3

1.52e-0421202CID000002023
Drugfluo-3

KCNMA1 RYR1 RYR3

1.60e-04122203CID000104978
DrugBAPTA

KCNMA1 NOS1 RYR1 RYR3

1.63e-04324204CID000104751
DrugClorocruoro Hem

NOS1 RYR1 RYR3

1.64e-04123203CID003518809
Drugpotassium

KCNMA1 NOS1 KCNV2 RYR1 RYR3 CPT1B

1.68e-041008206CID000000813
DrugAY9944

KCNMA1 GPR182

1.83e-0423202CID000009704
Drug4-phenylimidazole

NOS1 GPR182

2.00e-0424202CID000069590
DrugT0702

RYR1 RYR3

2.17e-0425202CID000005908
Druglanthanum

CBR3 RYR1 RYR3

2.21e-04136203CID000023926
DrugKn 04

RYR1 RYR3

2.35e-0426202CID000131117
Drugzaprinast

NOS1 RYR1 RYR3

2.45e-04141203CID000005722
Drugcarbachol

KCNMA1 NOS1 RYR1 RYR3 CPT1B

2.64e-04688205CID000002551
DrugDantrolene-13C3

NOS1 RYR1 RYR3

2.66e-04145203CID000002951
Drugdiad

RYR1 RYR3

2.73e-0428202CID000075555
Drugrhod-2

RYR1 RYR3

2.73e-0428202CID000123669
Drug8-dehydrocholesterol

KCNMA1 GPR182

2.73e-0428202CID000129846
Drugperoxynitrite

KCNMA1 NOS1 RYR1 RYR3

2.79e-04373204CID000104806
Drugbarium

KCNMA1 NOS1 CPT1B

2.83e-04148203CID000104810
DrugU-37883A

KCNMA1 GPR182

2.93e-0429202CID000064392
Drug2,4-xylidinothiazoline

RYR1 RYR3

3.14e-0430202CID000099296
DrugLOPAC

RYR1 RYR3

3.14e-0430202CID000062696
Drugcobalt-60

KCNMA1 RYR1 RYR3 CPT1B

3.30e-04390204CID000061492
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

1.31e-063202DOID:8545 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

1.31e-063202DOID:3529 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

KCNMA1 RYR1 RHBDL2 RYR3

8.25e-06195204DOID:1574 (implicated_via_orthology)
Diseasepulmonary hypertension (biomarker_via_orthology)

RYR1 GPR182 RYR3

2.12e-0580203DOID:6432 (biomarker_via_orthology)
Diseaseurate measurement, bone density

KCNMA1 DNAH8 DNAH9 CRBN

7.11e-04619204EFO_0003923, EFO_0004531
DiseasePetit mal status

KCNMA1 NOS1

9.40e-0467202C0270823
DiseaseStatus Epilepticus, Subclinical

KCNMA1 NOS1

9.40e-0467202C0751522
DiseaseSimple Partial Status Epilepticus

KCNMA1 NOS1

9.40e-0467202C0751524
DiseaseNon-Convulsive Status Epilepticus

KCNMA1 NOS1

9.40e-0467202C0751523
DiseaseGrand Mal Status Epilepticus

KCNMA1 NOS1

9.40e-0467202C0311335
DiseaseComplex Partial Status Epilepticus

KCNMA1 NOS1

9.40e-0467202C0393734
DiseaseStatus Epilepticus

KCNMA1 NOS1

9.68e-0468202C0038220
Diseaseschizophrenia (implicated_via_orthology)

NOS1 LRRN3

9.68e-0468202DOID:5419 (implicated_via_orthology)
Diseaseamino acid measurement

CMAHP KCNMA1 DNAH7 RYR3

9.98e-04678204EFO_0005134
Diseasebasophil percentage of granulocytes

CRBN RYR1

1.44e-0383202EFO_0007995
DiseaseBell's palsy

KCNMA1 DNAH8

2.16e-03102202EFO_0007167
Diseaseresponse to vaccine

DNAH9 CRBN

3.07e-03122202EFO_0004645
DiseasePapillary Renal Cell Carcinoma

KCNMA1 RYR1

3.37e-03128202C1306837

Protein segments in the cluster

PeptideGeneStartEntry
DSCQVIPVLPQVMMI

CRBN

76

Q96SW2
LCLGESPVVMPIHMQ

RAI2

81

Q9Y5P3
MDALIIPVTMEVPCD

KCNMA1

66

Q12791
LAKPPHLIMRIMDCV

DNAH8

3176

Q96JB1
DIQHKGMNPCPMVLV

NOS1

1271

P29475
RCMHLMLDHIPQVPQ

PXDNL

36

A1KZ92
IMVELPQLTIHQMPC

FUCA2

441

Q9BTY2
IKLVDIQIMCAMGPP

DNAH7

2081

Q8WXX0
MCNELLPIMKPHGRV

CBR3

121

O75828
IIPIPEQSMVQMVCH

DNAH9

2336

Q9NYC9
VEEMCPDIPVLERLM

RYR1

3236

P21817
EEIKPVMALGIVPMC

CPT1B

291

Q92523
CMQLVLGIPLEMVHK

RHBDL2

141

Q9NX52
HFRDMMEICLPLIAP

LRRN3

411

Q9H3W5
HIQLVEGPEPMCLFM

GPR182

191

O15218
PDLRPILEHVEMLCM

KCNV2

296

Q8TDN2
ILMDGVHPEMDTCII

CMAHP

156

Q9Y471
EMPHVIEVILPMLCN

RYR3

3126

Q15413
QDIPIPMLSELCEAM

TMOD4

206

Q9NZQ9
QELMEMCHKPEVELL

TRIM43B

231

A6NCK2