Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix constituent, lubricant activity	MUC3A MUC4	6.04e-05	4	64	2	GO:0030197
GeneOntologyMolecularFunction	GTPase activator activity	ARHGAP42 AGAP7P AGAP4 AGAP6 SOS1 SYNGAP1	2.68e-04	279	64	6	GO:0005096
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	PCLO BSN	2.80e-04	8	64	2	GO:0098882
GeneOntologyBiologicalProcess	synapse organization	EPHB3 DIP2A DRP2 ABI3BP NRXN2 PCLO NBEA BSN DCLK1 NRP2 NEDD4 SYNGAP1	1.56e-06	685	66	12	GO:0050808
GeneOntologyBiologicalProcess	cell junction organization	EPHB3 DIP2A DRP2 ABI3BP NRXN2 HIPK1 PCLO NBEA BSN DCLK1 NRP2 NEDD4 SYNGAP1	1.07e-05	974	66	13	GO:0034330
GeneOntologyBiologicalProcess	presynapse to nucleus signaling pathway	PCLO BSN	3.02e-05	3	66	2	GO:0099526
GeneOntologyBiologicalProcess	regulation of synapse structure or activity	EPHB3 DIP2A ABI3BP NRXN2 DCLK1 NRP2 NEDD4 SYNGAP1	3.67e-05	395	66	8	GO:0050803
GeneOntologyBiologicalProcess	cell projection morphogenesis	EPHB3 DIP2A NKX2-8 ABI3BP NCAM1 MUC3A DCLK1 NRP2 NEDD4 SOS1 SYNGAP1	5.70e-05	826	66	11	GO:0048858
GeneOntologyBiologicalProcess	presynaptic signal transduction	PCLO BSN	6.03e-05	4	66	2	GO:0098928
GeneOntologyBiologicalProcess	postsynapse organization	EPHB3 DIP2A ABI3BP NRXN2 DCLK1 NRP2 SYNGAP1	6.27e-05	313	66	7	GO:0099173
GeneOntologyBiologicalProcess	cranial nerve development	NEUROG1 SALL1 SCN8A NRP2	6.30e-05	67	66	4	GO:0021545
GeneOntologyBiologicalProcess	presynaptic active zone assembly	PCLO BSN	1.00e-04	5	66	2	GO:1904071
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	EPHB3 DIP2A NKX2-8 ABI3BP NCAM1 DCLK1 NRP2 NEDD4 SOS1 SYNGAP1	1.24e-04	748	66	10	GO:0048667
GeneOntologyBiologicalProcess	maintenance of presynaptic active zone structure	PCLO BSN	1.50e-04	6	66	2	GO:0048790
GeneOntologyBiologicalProcess	vestibulocochlear nerve morphogenesis	NEUROG1 NRP2	2.10e-04	7	66	2	GO:0021648
GeneOntologyBiologicalProcess	neuron projection morphogenesis	EPHB3 DIP2A NKX2-8 ABI3BP NCAM1 DCLK1 NRP2 NEDD4 SOS1 SYNGAP1	2.19e-04	802	66	10	GO:0048812
GeneOntologyBiologicalProcess	regulation of synapse organization	EPHB3 DIP2A ABI3BP NRXN2 DCLK1 NRP2 NEDD4	2.33e-04	387	66	7	GO:0050807
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	EPHB3 DIP2A NKX2-8 ABI3BP NCAM1 DCLK1 NRP2 NEDD4 SOS1 SYNGAP1	2.59e-04	819	66	10	GO:0120039
GeneOntologyBiologicalProcess	maintenance of synapse structure	PCLO BSN SYNGAP1	2.84e-04	40	66	3	GO:0099558
GeneOntologyBiologicalProcess	cell morphogenesis	EPHB3 DIP2A NKX2-8 ABI3BP FRMD6 NCAM1 MUC3A DCLK1 NRP2 NEDD4 SOS1 SYNGAP1	3.60e-04	1194	66	12	GO:0000902
GeneOntologyBiologicalProcess	nerve development	NEUROG1 SALL1 SCN8A NRP2	4.13e-04	109	66	4	GO:0021675
GeneOntologyBiologicalProcess	activation of GTPase activity	ARHGAP42 AGAP7P AGAP4 AGAP6	4.13e-04	109	66	4	GO:0090630
GeneOntologyBiologicalProcess	dendrite morphogenesis	EPHB3 DIP2A ABI3BP DCLK1 NEDD4	4.31e-04	198	66	5	GO:0048813
GeneOntologyBiologicalProcess	presynaptic active zone organization	PCLO BSN	4.46e-04	10	66	2	GO:1990709
GeneOntologyBiologicalProcess	synapse assembly	EPHB3 ABI3BP NRXN2 PCLO BSN DCLK1	4.52e-04	308	66	6	GO:0007416
GeneOntologyBiologicalProcess	protein localization to synapse	NRXN2 PCLO NBEA BSN	5.06e-04	115	66	4	GO:0035418
GeneOntologyBiologicalProcess	vestibulocochlear nerve development	NEUROG1 NRP2	5.44e-04	11	66	2	GO:0021562
GeneOntologyBiologicalProcess	learned vocalization behavior or vocal learning	NEUROG1 NRXN2	5.44e-04	11	66	2	GO:0098598
GeneOntologyBiologicalProcess	neuron projection development	EPHB3 DIP2A NKX2-8 NEUROG1 ABI3BP NCKIPSD NCAM1 DCLK1 NRP2 NEDD4 SOS1 SYNGAP1	6.96e-04	1285	66	12	GO:0031175
GeneOntologyBiologicalProcess	dendrite development	EPHB3 DIP2A ABI3BP DCLK1 NEDD4 SYNGAP1	7.03e-04	335	66	6	GO:0016358
GeneOntologyBiologicalProcess	regulation of GTPase activity	EPHB3 ARHGAP42 AGAP7P AGAP4 AGAP6 SYNGAP1	7.03e-04	335	66	6	GO:0043087
GeneOntologyBiologicalProcess	trigeminal nerve development	NEUROG1 NRP2	7.69e-04	13	66	2	GO:0021559
GeneOntologyBiologicalProcess	postsynaptic density organization	ABI3BP NRXN2 SYNGAP1	8.51e-04	58	66	3	GO:0097106
GeneOntologyCellularComponent	glutamatergic synapse	PRUNE2 DIP2A DRP2 NRXN2 PCLO SCN8A NCAM1 NBEA BSN DCLK1 NRP2 NEDD4 SYNGAP1	1.36e-06	817	66	13	GO:0098978
GeneOntologyCellularComponent	postsynapse	DIP2A DRP2 ABI3BP PCLO SCN8A NCAM1 NBEA BSN CHRM5 DCLK1 NRP2 NEDD4 SYNGAP1	1.48e-05	1018	66	13	GO:0098794
GeneOntologyCellularComponent	somatodendritic compartment	EPHB3 DIP2A NEUROG1 DRP2 ABI3BP PCLO SCN8A NCAM1 LMTK3 BSN CHRM5 NEDD4 SOS1 SYNGAP1	2.36e-05	1228	66	14	GO:0036477
GeneOntologyCellularComponent	dendrite	EPHB3 DIP2A DRP2 ABI3BP PCLO SCN8A LMTK3 BSN CHRM5 NEDD4 SYNGAP1	7.11e-05	858	66	11	GO:0030425
GeneOntologyCellularComponent	dendritic tree	EPHB3 DIP2A DRP2 ABI3BP PCLO SCN8A LMTK3 BSN CHRM5 NEDD4 SYNGAP1	7.26e-05	860	66	11	GO:0097447
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	PCLO BSN	2.72e-04	8	66	2	GO:0048788
GeneOntologyCellularComponent	Golgi lumen	MUC16 MUC12 MUC3A MUC4	3.93e-04	109	66	4	GO:0005796
GeneOntologyCellularComponent	postsynaptic density	DRP2 ABI3BP PCLO SCN8A BSN DCLK1 SYNGAP1	5.40e-04	451	66	7	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	DRP2 ABI3BP PCLO SCN8A BSN DCLK1 SYNGAP1	7.51e-04	477	66	7	GO:0032279
GeneOntologyCellularComponent	presynaptic cytoskeleton	PCLO BSN	8.72e-04	14	66	2	GO:0099569
GeneOntologyCellularComponent	postsynaptic specialization	DRP2 ABI3BP PCLO SCN8A BSN DCLK1 SYNGAP1	1.02e-03	503	66	7	GO:0099572
GeneOntologyCellularComponent	presynaptic active zone	NRXN2 PCLO SCN8A BSN	1.03e-03	141	66	4	GO:0048786
GeneOntologyCellularComponent	neuron to neuron synapse	DRP2 ABI3BP PCLO SCN8A BSN DCLK1 SYNGAP1	1.28e-03	523	66	7	GO:0098984
GeneOntologyCellularComponent	synaptic membrane	NRXN2 SCN8A NCAM1 NBEA BSN CHRM5 NRP2	2.38e-03	583	66	7	GO:0097060
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	PCLO BSN	2.38e-03	23	66	2	GO:0098831
MousePheno	abnormal synaptic vesicle number	PCLO NBEA BSN NEDD4	2.31e-05	42	56	4	MP:0004792
MousePheno	abnormal synaptic vesicle morphology	PCLO NBEA BSN NEDD4	5.02e-05	51	56	4	MP:0004769
MousePheno	abnormal mouth morphology	DIP2A ABI3BP MAP3K11 NBEA TWSG1 EYA1 AGAP7P AGAP4 AGAP6 NEDD4 SOS1	5.85e-05	670	56	11	MP:0000452
MousePheno	abnormal accessory nerve morphology	NKX2-8 NEUROG1	9.41e-05	4	56	2	MP:0001075
MousePheno	abnormal head morphology	DIP2A ABI3BP MAP3K11 NBEA TWSG1 EYA1 HUWE1 AGAP7P AGAP4 AGAP6 SON NRP2 NEDD4 SOS1	9.84e-05	1120	56	14	MP:0000432
MousePheno	abnormal viscerocranium morphology	DIP2A ABI3BP MAP3K11 TWSG1 EYA1 AGAP7P AGAP4 AGAP6 NEDD4 SOS1	1.07e-04	593	56	10	MP:0005274
MousePheno	fused cornea and lens	AGAP7P AGAP4 AGAP6	1.16e-04	24	56	3	MP:0001307
MousePheno	abnormal thyroid gland isthmus morphology	TULP4 EYA1	1.56e-04	5	56	2	MP:0013162
MousePheno	myoclonus	SCN8A BSN NRP2	2.07e-04	29	56	3	MP:0000243
MousePheno	abnormal facial morphology	DIP2A ABI3BP MAP3K11 NBEA TWSG1 EYA1 AGAP7P AGAP4 AGAP6 NRP2 NEDD4 SOS1	2.09e-04	910	56	12	MP:0003743
MousePheno	abnormal jaw morphology	DIP2A ABI3BP MAP3K11 TWSG1 EYA1 AGAP7P AGAP4 AGAP6 NEDD4	2.34e-04	530	56	9	MP:0000454
MousePheno	abnormal glossopharyngeal ganglion morphology	NEUROG1 EYA1 NEDD4	2.78e-04	32	56	3	MP:0001096
MousePheno	abnormal muscle physiology	ARHGAP42 PPP1R3A ABI3BP TULP4 SPEG SCN8A NBEA CMYA5 BSN CHRM5 NRP2 SOS1	3.23e-04	954	56	12	MP:0002106
Domain	PH_dom-like	ARHGAP42 FRMD6 NBEA AGAP7P PLEKHH2 AGAP4 AGAP6 FRMD4B SOS1 SYNGAP1	2.31e-06	426	66	10	IPR011993
Domain	Znf_piccolo	PCLO BSN	1.23e-05	2	66	2	IPR008899
Domain	zf-piccolo	PCLO BSN	1.23e-05	2	66	2	PF05715
Domain	PH	ARHGAP42 AGAP7P PLEKHH2 AGAP4 AGAP6 SOS1 SYNGAP1	5.52e-05	278	66	7	SM00233
Domain	PH_DOMAIN	ARHGAP42 AGAP7P PLEKHH2 AGAP4 AGAP6 SOS1 SYNGAP1	5.65e-05	279	66	7	PS50003
Domain	PH_domain	ARHGAP42 AGAP7P PLEKHH2 AGAP4 AGAP6 SOS1 SYNGAP1	5.78e-05	280	66	7	IPR001849
Domain	-	ARHGAP42 FRMD6 PLEKHH2 AGAP4 AGAP6 FRMD4B SOS1 SYNGAP1	6.83e-05	391	66	8	2.30.29.30
Domain	SEA	MUC16 MUC12 MUC3A	7.10e-05	23	66	3	PS50024
Domain	SEA_dom	MUC16 MUC12 MUC3A	7.10e-05	23	66	3	IPR000082
Domain	DMAP_binding	DIP2A DIP2C	1.22e-04	5	66	2	PF06464
Domain	ArfGap	AGAP7P AGAP4 AGAP6	1.44e-04	29	66	3	SM00105
Domain	ArfGap	AGAP7P AGAP4 AGAP6	1.44e-04	29	66	3	PF01412
Domain	ARFGAP	AGAP7P AGAP4 AGAP6	1.44e-04	29	66	3	PS50115
Domain	ArfGAP	AGAP7P AGAP4 AGAP6	1.44e-04	29	66	3	IPR001164
Domain	PH	ARHGAP42 AGAP7P PLEKHH2 AGAP4 SOS1 SYNGAP1	1.56e-04	229	66	6	PF00169
Domain	DMAP1-bd	DIP2A DIP2C	1.83e-04	6	66	2	IPR010506
Domain	DMAP_binding	DIP2A DIP2C	1.83e-04	6	66	2	SM01137
Domain	fn3	EPHB3 ABI3BP SPEG NCAM1 CMYA5	2.69e-04	162	66	5	PF00041
Domain	FN3	EPHB3 ABI3BP SPEG NCAM1 CMYA5	4.95e-04	185	66	5	SM00060
Domain	FERM_M	FRMD6 PLEKHH2 FRMD4B	5.74e-04	46	66	3	PF00373
Domain	FN3	EPHB3 ABI3BP SPEG NCAM1 CMYA5	6.89e-04	199	66	5	PS50853
Domain	-	FRMD6 PLEKHH2 FRMD4B	6.91e-04	49	66	3	1.20.80.10
Domain	FERM_central	FRMD6 PLEKHH2 FRMD4B	6.91e-04	49	66	3	IPR019748
Domain	FERM_domain	FRMD6 PLEKHH2 FRMD4B	6.91e-04	49	66	3	IPR000299
Domain	FERM_1	FRMD6 PLEKHH2 FRMD4B	7.34e-04	50	66	3	PS00660
Domain	FERM_2	FRMD6 PLEKHH2 FRMD4B	7.34e-04	50	66	3	PS00661
Domain	FERM_3	FRMD6 PLEKHH2 FRMD4B	7.34e-04	50	66	3	PS50057
Domain	Band_41_domain	FRMD6 PLEKHH2 FRMD4B	7.34e-04	50	66	3	IPR019749
Domain	B41	FRMD6 PLEKHH2 FRMD4B	7.34e-04	50	66	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	FRMD6 PLEKHH2 FRMD4B	7.34e-04	50	66	3	IPR014352
Domain	FN3_dom	EPHB3 ABI3BP SPEG NCAM1 CMYA5	8.59e-04	209	66	5	IPR003961
Domain	SEA	MUC16 MUC3A	1.09e-03	14	66	2	SM00200
Domain	SEA	MUC16 MUC12	2.71e-03	22	66	2	PF01390
Domain	SAM	EPHB3 SASH3 PHC2	3.73e-03	88	66	3	SM00454
Domain	FERM_C	FRMD6 FRMD4B	3.78e-03	26	66	2	PF09380
Domain	RASGEF	RAPGEFL1 SOS1	3.78e-03	26	66	2	PS00720
Domain	HECT	HUWE1 NEDD4	4.08e-03	27	66	2	PF00632
Domain	HECTc	HUWE1 NEDD4	4.08e-03	27	66	2	SM00119
Domain	HECT_dom	HUWE1 NEDD4	4.08e-03	27	66	2	IPR000569
Domain	FERM_C	FRMD6 FRMD4B	4.08e-03	27	66	2	SM01196
Domain	FERM_PH-like_C	FRMD6 FRMD4B	4.08e-03	27	66	2	IPR018980
Domain	HECT	HUWE1 NEDD4	4.08e-03	27	66	2	PS50237
Domain	SAM_DOMAIN	EPHB3 SASH3 PHC2	4.63e-03	95	66	3	PS50105
Domain	RASGEF_CAT	RAPGEFL1 SOS1	4.70e-03	29	66	2	PS50009
Domain	SAM	EPHB3 SASH3 PHC2	4.90e-03	97	66	3	IPR001660
Domain	AMP-binding	DIP2A DIP2C	5.02e-03	30	66	2	PF00501
Domain	RasGEF	RAPGEFL1 SOS1	5.02e-03	30	66	2	PF00617
Domain	-	RAPGEFL1 SOS1	5.02e-03	30	66	2	1.10.840.10
Domain	Ras_GEF_dom	RAPGEFL1 SOS1	5.02e-03	30	66	2	IPR023578
Domain	RASGEF_cat_dom	RAPGEFL1 SOS1	5.02e-03	30	66	2	IPR001895
Domain	AMP-dep_Synth/Lig	DIP2A DIP2C	5.02e-03	30	66	2	IPR000873
Domain	UBA	UBAP2L HUWE1	5.02e-03	30	66	2	SM00165
Domain	RasGEF	RAPGEFL1 SOS1	5.02e-03	30	66	2	SM00147
Domain	PROTEIN_KINASE_ATP	EPHB3 HIPK1 SPEG MAP3K11 LMTK3 DCLK1	5.58e-03	459	66	6	PS00107
Domain	FERM_N	FRMD6 FRMD4B	6.05e-03	33	66	2	PF09379
Domain	FERM_N	FRMD6 FRMD4B	6.05e-03	33	66	2	IPR018979
Domain	-	EPHB3 SASH3 PHC2	6.27e-03	106	66	3	1.10.150.50
Domain	MAGE	MAGEB5 MAGEC1	6.41e-03	34	66	2	SM01373
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC16 MUC12 MUC3A MUC4	1.21e-07	16	42	4	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC16 MUC12 MUC3A MUC4	1.57e-07	17	42	4	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC16 MUC12 MUC3A MUC4	5.78e-07	23	42	4	M556
Pathway	REACTOME_DECTIN_2_FAMILY	MUC16 MUC12 MUC3A MUC4	9.70e-07	26	42	4	M27483
Pathway	REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	MUC16 MUC12 MUC3A MUC4	3.35e-05	62	42	4	M546
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	MUC16 MUC12 MUC3A MUC4	4.83e-05	68	42	4	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	MUC16 MUC12 MUC3A MUC4	3.24e-04	111	42	4	M27416
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	UBAP2L HIPK1 PCLO NCAM1 NBEA LMTK3 BSN DCLK1 SOS1 SYNGAP1	1.10e-09	347	66	10	17114649
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP7P AGAP4 AGAP6 CHRM5	2.46e-09	10	66	4	20664521
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	PCLO NCAM1 NBEA AGAP7P AGAP4 AGAP6 DCLK1 NEDD4 SYNGAP1	3.19e-09	281	66	9	28706196
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 SALL1 TULP4 LMTK3 BSN NUP153 SON NEDD4 SOS1 SYNGAP1	8.56e-09	430	66	10	35044719
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC16 MUC12 MUC3A MUC4	3.55e-08	18	66	4	18834073
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SPEG PCLO NCAM1 LMTK3 BSN DCLK1 NEDD4	2.91e-07	231	66	7	16452087
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP7P AGAP4 AGAP6	5.44e-07	9	66	3	12640130
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIP2A PCLO NBEA HUWE1 DCLK1	6.91e-07	87	66	5	12465718
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP7P AGAP4 AGAP6	1.07e-06	11	66	3	15381706
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HIVEP3 PHRF1 NBEA CEP192 HUWE1	1.45e-06	101	66	5	10997877
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP7P AGAP4 AGAP6	1.84e-06	13	66	3	27713690
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	UBAP2L NCAM1 NBEA HUWE1 LMTK3 BSN DCLK1 NUP153 LRRC15 NEDD4 SYNGAP1	1.85e-06	963	66	11	28671696
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP7P AGAP4 AGAP6	2.34e-06	14	66	3	22453919
Pubmed	MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion.	MUC16 NRP2	3.55e-06	2	66	2	35533267
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	PCLO BSN	3.55e-06	2	66	2	23403927
Pubmed	Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 (dip2), and its murine homolog.	DIP2A DIP2C	3.55e-06	2	66	2	12137943
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	PCLO BSN	3.55e-06	2	66	2	26793095
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	PCLO BSN	3.55e-06	2	66	2	20332206
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	PCLO BSN	3.55e-06	2	66	2	21935939
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	3.55e-06	2	66	2	23544943
Pubmed	Familial transmission of oculoauriculovertebral spectrum (Goldenhar syndrome) is not due to mutations in either EYA1 or SALL1.	SALL1 EYA1	3.55e-06	2	66	2	19213029
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	PCLO BSN	3.55e-06	2	66	2	27321892
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	PCLO BSN	3.55e-06	2	66	2	32493491
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	PCLO BSN	3.55e-06	2	66	2	25652077
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	PCLO AGAP7P BSN AGAP4 AGAP6 SYNGAP1	3.76e-06	218	66	6	33378226
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIVEP3 DIP2A TULP4 SPEG SCN8A DIP2C MAP3K11 CEP192 HUWE1 ELL PHC2	6.87e-06	1105	66	11	35748872
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	1.06e-05	3	66	2	23053434
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	1.06e-05	3	66	2	30236127
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	1.06e-05	3	66	2	17592322
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC12	1.06e-05	3	66	2	26770020
Pubmed	CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.	DIP2A DIP2C	1.06e-05	3	66	2	17236128
Pubmed	Mph2 expression in germinal zones of the mouse brain.	NCAM1 PHC2	1.06e-05	3	66	2	15580621
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	1.06e-05	3	66	2	35879412
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	1.06e-05	3	66	2	27483328
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	1.06e-05	3	66	2	24204560
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC4	1.06e-05	3	66	2	24939955
Pubmed	Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation.	SALL1 NCAM1 EYA1	1.28e-05	24	66	3	31142573
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	PHRF1 CEP192 LMTK3 ELL	1.68e-05	80	66	4	19389623
Pubmed	Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.	EPHB3 HUWE1	2.12e-05	4	66	2	27184401
Pubmed	mRNA 5' region sequence incompleteness: a potential source of systematic errors in translation initiation codon assignment in human mRNAs.	DIP2A SON	2.12e-05	4	66	2	14637006
Pubmed	TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.	MUC16 MUC4	2.12e-05	4	66	2	39024979
Pubmed	Two Nedd4-binding motifs underlie modulation of sodium channel Nav1.6 by p38 MAPK.	SCN8A NEDD4	2.12e-05	4	66	2	20530479
Pubmed	Polysialic acid on SynCAM 1 in NG2 cells and on neuropilin-2 in microglia is confined to intracellular pools that are rapidly depleted upon stimulation.	NCAM1 NRP2	3.53e-05	5	66	2	25752299
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	HUWE1 NEDD4	3.53e-05	5	66	2	28425671
Pubmed	Polysialylation and lipopolysaccharide-induced shedding of E-selectin ligand-1 and neuropilin-2 by microglia and THP-1 macrophages.	NCAM1 NRP2	3.53e-05	5	66	2	27159043
Pubmed	Expression of bHLH transcription factors NSCL1 and NSCL2 in the mouse olfactory system.	NEUROG1 NCAM1	3.53e-05	5	66	2	14578122
Pubmed	Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.	SALL1 NCAM1 EYA1	4.84e-05	37	66	3	16319116
Pubmed	An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.	NBEA DCLK1	5.29e-05	6	66	2	19482073
Pubmed	A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.	PCLO BSN	5.29e-05	6	66	2	19812333
Pubmed	β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.	HUWE1 NEDD4	5.29e-05	6	66	2	29964046
Pubmed	Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release.	PCLO BSN	5.29e-05	6	66	2	14734538
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRXN2 PHRF1 AGAP7P BSN AGAP4 AGAP6 FRMD4B	6.49e-05	529	66	7	14621295
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DIP2A NRXN2 UBAP2L PCLO SYNGR3 NCKIPSD NCAM1 NBEA BSN DCLK1 SYNGAP1	7.38e-05	1431	66	11	37142655
Pubmed	Eya1 acts upstream of Tbx1, Neurogenin 1, NeuroD and the neurotrophins BDNF and NT-3 during inner ear development.	NEUROG1 EYA1	7.40e-05	7	66	2	15817220
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	EPHB3 NCAM1 LRRC15 NRP2	7.46e-05	117	66	4	17145500
Pubmed	Brn3a regulates the transition from neurogenesis to terminal differentiation and represses non-neural gene expression in the trigeminal ganglion.	NEUROG1 EYA1 NRP2	8.75e-05	45	66	3	19877281
Pubmed	SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1.	MAP3K11 SOS1	9.86e-05	8	66	2	9346925
Pubmed	Widespread defects in the primary olfactory pathway caused by loss of Mash1 function.	NEUROG1 NCAM1	9.86e-05	8	66	2	12629181
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	UBAP2L PHRF1 HUWE1 TSSC4 NUP153 PHC2 SON SOS1	1.07e-04	774	66	8	15302935
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	PCLO NCAM1 BSN SYNGAP1	1.16e-04	131	66	4	28634551
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	NCAM1 NBEA DCLK1 LRRC15 SYNGAP1	1.17e-04	251	66	5	27507650
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBAP2L HIPK1 SPEG CEP192 SON NEDD4	1.24e-04	407	66	6	12693553
Pubmed	Differential interactions of cerebellin precursor protein (Cbln) subtypes and neurexin variants for synapse formation of cortical neurons.	NRXN2 BSN	1.27e-04	9	66	2	21356198
Pubmed	The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood.	NCAM1 EYA1	1.27e-04	9	66	2	37181748
Pubmed	Six1 is required for the early organogenesis of mammalian kidney.	SALL1 EYA1	1.27e-04	9	66	2	12783782
Pubmed	Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.	SON SYNGAP1	1.27e-04	9	66	2	11782456
Pubmed	A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system.	NEUROG1 NCAM1	1.27e-04	9	66	2	15716344
Pubmed	Superresolution imaging of chemical synapses in the brain.	PCLO BSN	1.27e-04	9	66	2	21144999
Pubmed	EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear.	NEUROG1 EYA1	1.27e-04	9	66	2	22513373
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	EPHB3 NRXN2	1.27e-04	9	66	2	9707552
Pubmed	Proteomic analysis of in vivo phosphorylated synaptic proteins.	PCLO NCAM1 BSN	1.43e-04	53	66	3	15572359
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DIP2A HIPK1 MAP3K11 NBEA HUWE1 CMYA5 FRMD4B DCLK1 SOS1 SYNGAP1	1.47e-04	1285	66	10	35914814
Pubmed	Disrupted development of the cerebral hemispheres in transgenic mice expressing the mammalian Groucho homologue transducin-like-enhancer of split 1 in postmitotic neurons.	NEUROG1 NCAM1	1.58e-04	10	66	2	10781944
Pubmed	Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation.	SALL1 NRP2	1.58e-04	10	66	2	30718617
Pubmed	Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme.	SALL1 EYA1	1.58e-04	10	66	2	16442091
Pubmed	Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11.	NEUROG1 NCAM1	1.58e-04	10	66	2	19297409
Pubmed	Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.	EPHB3 NRP2	1.93e-04	11	66	2	22171039
Pubmed	Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgfbeta1 regulate semaphorin 3a expression in the dental mesenchyme.	NCAM1 NRP2	1.93e-04	11	66	2	15604101
Pubmed	Mouse Hoxa2 mutations provide a model for microtia and auricle duplication.	TWSG1 EYA1	1.93e-04	11	66	2	24067355
Pubmed	Evidence for new homotypic and heterotypic interactions between transmembrane helices of proteins involved in receptor tyrosine kinase and neuropilin signaling.	MUC4 NRP2	1.93e-04	11	66	2	25315821
Pubmed	Eya1 regulates the growth of otic epithelium and interacts with Pax2 during the development of all sensory areas in the inner ear.	SALL1 EYA1	1.93e-04	11	66	2	16916509
Pubmed	Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate.	NEUROG1 NCAM1	1.93e-04	11	66	2	21852401
Pubmed	Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.	BSN NUP153	2.31e-04	12	66	2	28700933
Pubmed	Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development.	SALL1 EYA1	2.31e-04	12	66	2	11688560
Pubmed	Noses and neurons: induction, morphogenesis, and neuronal differentiation in the peripheral olfactory pathway.	NEUROG1 NCAM1	2.31e-04	12	66	2	16193510
Pubmed	Ephrin/ephrin receptor expression during early stages of mouse inner ear development.	EPHB3 NEUROG1	2.31e-04	12	66	2	21465626
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	PCLO BSN	2.31e-04	12	66	2	28386022
Pubmed	The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections.	NCAM1 NRP2	2.31e-04	12	66	2	25007825
Pubmed	The ATP-dependent chromatin remodeling enzyme CHD7 regulates pro-neural gene expression and neurogenesis in the inner ear.	NEUROG1 EYA1	2.31e-04	12	66	2	20736290
Pubmed	Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.	NKX2-8 NRP2	2.31e-04	12	66	2	28407732
Pubmed	Dicer function is required in the metanephric mesenchyme for early kidney development.	SALL1 NCAM1	2.31e-04	12	66	2	24500693
Pubmed	Secreted TARSH regulates olfactory mitral cell dendritic complexity.	PRUNE2 ABI3BP	2.31e-04	12	66	2	19302145
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	NEUROG1 NRXN2 NCAM1 NBEA CHRM5	2.68e-04	300	66	5	19086053
Pubmed	Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.	NCAM1 BSN	2.73e-04	13	66	2	20624980
Pubmed	Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse.	NEUROG1 NCAM1	2.73e-04	13	66	2	16267092
Pubmed	Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease.	SALL1 EYA1	2.73e-04	13	66	2	38692273
Pubmed	Sall1 regulates mitral cell development and olfactory nerve extension in the developing olfactory bulb.	SALL1 NCAM1	2.73e-04	13	66	2	18024993
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN8A NEDD4	2.73e-04	13	66	2	15123669
Pubmed	The novel helicase helG (DHX30) is expressed during gastrulation in mice and has a structure similar to a human DExH box helicase.	NEUROG1 NCAM1	2.73e-04	13	66	2	25219788
Pubmed	Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes.	NEUROG1 EYA1	2.73e-04	13	66	2	15496442
Cytoband	13q13	NBEA DCLK1	2.03e-05	5	66	2	13q13
Cytoband	Ensembl 112 genes in cytogenetic band chr10q11	TMEM72 AGAP7P AGAP4 AGAP6	1.61e-04	188	66	4	chr10q11
Cytoband	Xq26	SASH3 MAGEC1	1.83e-04	14	66	2	Xq26
Cytoband	10q11.23	AGAP7P AGAP6	1.04e-03	33	66	2	10q11.23
Cytoband	7q22	MUC12 MUC3A	1.38e-03	38	66	2	7q22
Cytoband	2p21	PLEKHH2 SOS1	3.53e-03	61	66	2	2p21
GeneFamily	CD molecules\|Mucins	MUC16 MUC12 MUC3A MUC4	2.53e-07	21	48	4	648
GeneFamily	ArfGAPs	AGAP7P AGAP4 AGAP6	9.06e-05	33	48	3	395
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R3A PHRF1 CEP192 LMTK3 ELL	1.15e-04	181	48	5	694
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AGAP7P PLEKHH2 AGAP4 AGAP6 SOS1	2.10e-04	206	48	5	682
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMD6 PLEKHH2 FRMD4B	3.15e-04	50	48	3	1293
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO BSN	7.09e-04	15	48	2	26
GeneFamily	Fibronectin type III domain containing	EPHB3 ABI3BP NCAM1 CMYA5	8.49e-04	160	48	4	555
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP4 AGAP6	9.15e-04	17	48	2	1291
GeneFamily	Sterile alpha motif domain containing	EPHB3 SASH3 PHC2	1.65e-03	88	48	3	760
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	NBEA CMYA5	2.68e-03	29	48	2	396
GeneFamily	MAGE family	MAGEB5 MAGEC1	5.05e-03	40	48	2	1136
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	HIVEP3 TULP4 NRXN2 SPEG PCLO SYNGR3 SCN8A NCAM1 NBEA BSN CHRM5 FRMD4B DCLK1 NRP2	5.20e-07	1106	66	14	M39071
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	HIVEP3 NRXN2 SPEG SCN8A NCAM1 NBEA EYA1 LMTK3 BSN	2.44e-06	465	66	9	M39066
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	TULP4 NRXN2 PCLO SYNGR3 SCN8A NCAM1 NBEA BSN FRMD4B DCLK1	9.84e-06	703	66	10	M39070
Coexpression	GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN	HIVEP3 FRMD6 HIPK1 IRF2 EYA1 BSN	1.14e-05	200	66	6	M8052
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	HIVEP3 TULP4 NRXN2 SYNGR3 SCN8A NCAM1 NBEA LMTK3 DCLK1	1.52e-05	584	66	9	M39068
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5	EPHB3 SSC5D DIP2A SALL1 TULP4 NRXN2 PCLO NCAM1 NBEA TWSG1 LMTK3	1.09e-05	722	65	11	Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_200	NCAM1 EYA1 DCLK1 NRP2	2.25e-05	54	65	4	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_200
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5	EPHB3 SSC5D DIP2A TULP4 NRXN2 PCLO NCAM1 NBEA TWSG1 LMTK3	7.19e-05	732	65	10	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	ARHGAP42 DRP2 ABI3BP MUC16 NCAM1 CEP192 EYA1 PLEKHH2 FRMD4B DCLK1	1.18e-04	777	65	10	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_500	NCAM1 EYA1 DCLK1 NRP2	1.28e-04	84	65	4	gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k1_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	ARHGAP42 DRP2 MUC16 NCAM1 CEP192 EYA1 PLEKHH2 FRMD4B DCLK1 SYNGAP1	1.39e-04	793	65	10	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000	ARHGAP42 DRP2 ABI3BP FRMD6 MUC16 NCAM1 PLEKHH2 FRMD4B DCLK1 SYNGAP1	1.45e-04	797	65	10	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5	EPHB3 SSC5D DIP2A TULP4 NRXN2 PCLO NCAM1 TWSG1 LMTK3	1.69e-04	658	65	9	Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#4	EPHB3 SSC5D DIP2A TULP4 NRXN2 PCLO NCAM1 TWSG1 LMTK3	2.23e-04	683	65	9	Facebase_RNAseq_e9.5_Olfactory Placode_2500_K4
CoexpressionAtlas	dev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000	MUC16 PLEKHH2 FRMD4B SYNGAP1	2.24e-04	97	65	4	gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#1	NEUROG1 FRMD6 EYA1 MUC4	2.92e-04	104	65	4	Facebase_RNAseq_e10.5_Olfactory Pit_500_K1
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_500	DRP2 MUC16 NCAM1 PLEKHH2 FRMD4B DCLK1 SYNGAP1	3.66e-04	436	65	7	gudmap_dev gonad_e11.5_F_GonMes_Sma_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	ARHGAP42 DRP2 FRMD6 DIP2C MUC16 NCAM1 PLEKHH2 DCLK1 SYNGAP1	4.03e-04	740	65	9	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_k-means-cluster#1_top-relative-expression-ranked_200	SALL1 NCAM1 EYA1	4.03e-04	47	65	3	gudmap_kidney_P4_CapMesRenVes_Crym_k1_200
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	EPHB3 DIP2A TULP4 NRXN2 PCLO NCAM1 NBEA TWSG1 LMTK3	4.15e-04	743	65	9	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2	EPHB3 SSC5D DIP2A TULP4 NRXN2 PCLO NCAM1 NBEA TWSG1	4.31e-04	747	65	9	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 ABI3BP FRMD6 FRMD4B LRRC15 NRP2	3.00e-07	182	66	6	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 ABI3BP FRMD6 FRMD4B LRRC15 NRP2	3.00e-07	182	66	6	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 ABI3BP FRMD6 FRMD4B LRRC15 NRP2	3.00e-07	182	66	6	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	PRUNE2 ABI3BP PCLO NCAM1 EYA1 CMYA5	3.86e-07	190	66	6	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 HIVEP3 ABI3BP FRMD6 PLEKHH2 NPAS2	3.86e-07	190	66	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP42 PRUNE2 MUC16 NBEA CMYA5 LMTK3	4.10e-07	192	66	6	8899d81306770adda893b5e146df1253971754c5
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP42 PRUNE2 MUC16 NBEA CMYA5 LMTK3	4.10e-07	192	66	6	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 NBEA EYA1 MUC4 NPAS2	4.13e-06	161	66	5	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	SYNGR3 NCAM1 CMYA5 FRMD4B NRP2	5.39e-06	170	66	5	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 NBEA EYA1 MUC4 NPAS2	5.86e-06	173	66	5	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ARHGAP42 NKX2-8 MUC16 LMTK3 MUC4	6.73e-06	178	66	5	9a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGAP42 NKX2-8 MUC16 LMTK3 MUC4	6.73e-06	178	66	5	b413a634283550fa224db7d0d05956e3f64694a1
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGAP42 NKX2-8 MUC16 LMTK3 MUC4	6.73e-06	178	66	5	49a2271718637522f74334068d252963ee13b1ce
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ARHGAP42 NKX2-8 MUC16 LMTK3 MUC4	6.73e-06	178	66	5	19b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 NBEA CMYA5 MUC4 RAPGEFL1	6.92e-06	179	66	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABI3BP CMYA5 PLEKHH2 BSN DCLK1	6.92e-06	179	66	5	dcd0a83f0592ae27f814d064b4791f84c3c86e64
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGAP42 PRUNE2 ABI3BP SPEG NCAM1	7.30e-06	181	66	5	25915e2500430a902db37d79a749ce2990b69810
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MUC16 NBEA EYA1 MUC4 NPAS2	7.50e-06	182	66	5	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABI3BP FRMD6 FRMD4B LRRC15 NRP2	7.70e-06	183	66	5	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PCLO SYNGR3 SCN8A BSN	7.91e-06	184	66	5	7d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 NBEA CMYA5 MUC4 NRP2	7.91e-06	184	66	5	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 PRUNE2 SSC5D ABI3BP SPEG	8.12e-06	185	66	5	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 PRUNE2 SSC5D ABI3BP SPEG	8.34e-06	186	66	5	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	ARHGAP42 NBEA EYA1 MUC4 NPAS2	8.55e-06	187	66	5	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 PRUNE2 SSC5D ABI3BP SPEG	8.78e-06	188	66	5	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PPP1R3A PRUNE2 SSC5D SPEG DCLK1	8.78e-06	188	66	5	74f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 PRUNE2 SSC5D ABI3BP SPEG	8.78e-06	188	66	5	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 PRUNE2 SSC5D ABI3BP SPEG	9.01e-06	189	66	5	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ARHGAP42 NKX2-8 MUC16 LMTK3 MUC4	9.01e-06	189	66	5	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NRXN2 PCLO SCN8A BSN	9.01e-06	189	66	5	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 FRMD6 NCAM1 PHC2 NRP2	9.01e-06	189	66	5	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 SSC5D ABI3BP FRMD6 SPEG	9.01e-06	189	66	5	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	ARHGAP42 NBEA EYA1 MUC4 NPAS2	9.24e-06	190	66	5	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 FRMD6 NCAM1 PHC2 NRP2	9.24e-06	190	66	5	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 FRMD6 NCAM1 PHC2 NRP2	9.24e-06	190	66	5	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP TWSG1 CMYA5 DCLK1 NEDD4	9.24e-06	190	66	5	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 FRMD6 NCAM1 PHC2 NRP2	9.48e-06	191	66	5	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 FRMD6 NCAM1 PHC2 NRP2	9.48e-06	191	66	5	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 SSC5D ABI3BP FRMD6 SPEG	9.48e-06	191	66	5	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 FRMD6 PCLO LRRC15 NRP2	9.72e-06	192	66	5	b016e229300c183e14c0e2bba494bf49c7899112
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP42 PRUNE2 SSC5D ABI3BP SPEG	9.72e-06	192	66	5	992d08092edbc68c47b945deb8708379738c239a
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 FRMD6 PCLO LRRC15 NRP2	9.72e-06	192	66	5	ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB3 SALL1 TMEM72 LMTK3 PLEKHH2	9.72e-06	192	66	5	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 PCLO SCN8A BSN RAPGEFL1	9.97e-06	193	66	5	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SYNGR3 SCN8A NBEA LMTK3 BSN	9.97e-06	193	66	5	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 PCLO SCN8A BSN RAPGEFL1	9.97e-06	193	66	5	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 PCLO SCN8A BSN RAPGEFL1	9.97e-06	193	66	5	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC5D ABI3BP NCAM1 TWSG1 NEDD4	9.97e-06	193	66	5	eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NRXN2 PCLO SCN8A BSN	9.97e-06	193	66	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP NCAM1 TWSG1 DCLK1 NEDD4	1.02e-05	194	66	5	48063c9fe3e12aeff0707acada1baa2f8621f093
ToppCell	facs-Heart-RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP NCAM1 TWSG1 DCLK1 NEDD4	1.02e-05	194	66	5	c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP NCAM1 TWSG1 DCLK1 NEDD4	1.02e-05	194	66	5	4f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PCLO SYNGR3 SCN8A LMTK3 BSN	1.02e-05	194	66	5	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	distal-Epithelial-Differentiating_Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NKX2-8 CMYA5 LMTK3 MUC4 RAPGEFL1	1.05e-05	195	66	5	3fe6e49a9161fc9e5160251e6932cb5378175a54
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PCLO LMTK3 TSSC4 MUC4	1.05e-05	195	66	5	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TULP4 PCLO NBEA HUWE1 SON	1.05e-05	195	66	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SALL1 ABI3BP NCAM1 PLEKHH2 LRRC15	1.07e-05	196	66	5	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	ABI3BP FRMD6 DIP2C PLEKHH2 DCLK1	1.10e-05	197	66	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	ABI3BP FRMD6 DIP2C PLEKHH2 DCLK1	1.10e-05	197	66	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABI3BP FRMD6 TWSG1 DCLK1 NEDD4	1.13e-05	198	66	5	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 SPEG CMYA5 PLEKHH2 NRP2	1.13e-05	198	66	5	cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	HIVEP3 ABI3BP FRMD6 PLEKHH2 LRRC15	1.16e-05	199	66	5	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 SSC5D ABI3BP FRMD6 CMYA5	1.16e-05	199	66	5	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP42 SSC5D ABI3BP FRMD6 NRXN2	1.16e-05	199	66	5	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HIVEP3 ABI3BP FRMD6 PLEKHH2 LRRC15	1.16e-05	199	66	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRMD6 MUC16 EYA1 MUC4 RAPGEFL1	1.16e-05	199	66	5	f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 NBEA EYA1 MUC4 NPAS2	1.18e-05	200	66	5	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 NBEA EYA1 CMYA5 NPAS2	1.18e-05	200	66	5	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	HIVEP3 NRXN2 PCLO NCAM1 NBEA	1.18e-05	200	66	5	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 SSC5D ABI3BP FRMD6 CMYA5	1.18e-05	200	66	5	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP NCAM1	1.18e-05	200	66	5	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer\|World / Primary Cells by Cluster	PCLO NCAM1 NBEA FRMD4B DCLK1	1.18e-05	200	66	5	db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21\|World / Primary Cells by Cluster	PCLO NCAM1 NBEA FRMD4B DCLK1	1.18e-05	200	66	5	30a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRMD6 EYA1 MUC4 RAPGEFL1 NPAS2	1.18e-05	200	66	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGAP42 PRUNE2 SSC5D ABI3BP FRMD6	1.18e-05	200	66	5	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 CMYA5 LMTK3 MUC4 RAPGEFL1	1.18e-05	200	66	5	ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NCKIPSD AGAP4 AGAP6 RAPGEFL1	1.95e-05	107	66	4	410b37beffaf637a2a64c9d0ce7baf81f4bc667c
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NCKIPSD AGAP4 AGAP6 RAPGEFL1	1.95e-05	107	66	4	5bae4b3aede9bcbf7e88414e3453973cc8b0c3e7
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIIP EPHB3 DRP2 DCLK1	3.36e-05	123	66	4	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NKX2-8 SPEG PCLO NCAM1	3.93e-05	128	66	4	2cf0384240a4a663869cf6b27d954236f6214a9a
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DRP2 SASH3 BSN RPA2	7.67e-05	152	66	4	3951a9f5fe164002311ed2ef7c36ae958451826b
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-valve_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3A SASH3 TMEM72 LRRC15	7.86e-05	153	66	4	1440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CMYA5 LMTK3 DCLK1 NRP2	8.48e-05	156	66	4	bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP3 ABI3BP PLEKHH2 LRRC15	8.91e-05	158	66	4	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP42 NRXN2 SCN8A NRP2	1.00e-04	163	66	4	f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP42 PRUNE2 SSC5D SPEG	1.03e-04	164	66	4	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	UBAP2L HIPK1 SON SYNGAP1	1.08e-04	166	66	4	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	ABI3BP PLEKHH2 DCLK1 ELL	1.15e-04	169	66	4	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	Ciliated_cells-A-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	PRUNE2 MUC16 NBEA FAM221B	1.18e-04	170	66	4	3d3a03979014df3a05c49be18010c6b94d786707
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP42 ZNF474 AGAP4 SYNGAP1	1.29e-04	174	66	4	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PCLO MUC16 LMTK3 MUC4	1.29e-04	174	66	4	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	MUC16 NBEA EYA1 NPAS2	1.29e-04	174	66	4	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 MUC3A MUC4 RAPGEFL1	1.29e-04	174	66	4	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SSC5D ABI3BP PLEKHH2 NRP2	1.32e-04	175	66	4	1799a7be623dc3bf53ba580a7c47d2619969d708
Drug	cellobiitol	MUC12 MUC3A MUC4 SOS1	3.96e-06	37	66	4	CID000003871
Disease	cerebral palsy (implicated_via_orthology)	AGAP7P AGAP4 AGAP6	1.21e-06	10	65	3	DOID:1969 (implicated_via_orthology)
Disease	cholangiocarcinoma (is_marker_for)	MUC16 NCAM1 MUC3A MUC4	1.23e-05	64	65	4	DOID:4947 (is_marker_for)
Disease	creatinine measurement	PPP1R3A NRXN2 SPEG DIP2C MAP3K11 EYA1 PLEKHH2 BSN ELL PHC2	6.05e-05	995	65	10	EFO_0004518
Disease	Congenital small ears	SALL1 TWSG1 EYA1	1.02e-04	41	65	3	C0152423
Disease	Schizophrenia	NEUROG1 NRXN2 NCAM1 MAGEC1 CMYA5 CHRM5 DCLK1 NPAS2 SYNGAP1	1.32e-04	883	65	9	C0036341
Disease	Congenital Abnormality	SALL1 EYA1	2.59e-04	11	65	2	C0000768
Disease	Autistic Disorder	NRXN2 NBEA NRP2 NPAS2 SYNGAP1	2.79e-04	261	65	5	C0004352
Disease	autism spectrum disorder (implicated_via_orthology)	NRXN2 NBEA NRP2 SYNGAP1	3.59e-04	152	65	4	DOID:0060041 (implicated_via_orthology)
Disease	cup-to-disc ratio measurement	ARHGAP42 SALL1 ABI3BP NCKIPSD EYA1 DCLK1	3.70e-04	430	65	6	EFO_0006939
Disease	Bipolar Disorder	PCLO SCN8A NCAM1 DCLK1 NEDD4 NPAS2	6.38e-04	477	65	6	C0005586
Disease	gout	NRXN2 MAP3K11 FRMD4B SOS1	9.31e-04	196	65	4	EFO_0004274
Disease	eye color	HIVEP3 TULP4 MUC16	1.05e-03	90	65	3	EFO_0003949
Disease	Neurodevelopmental Disorders	HIVEP3 SCN8A SYNGAP1	1.15e-03	93	65	3	C1535926
Disease	pancreatic cancer (is_marker_for)	MUC16 NCAM1 MUC4	1.46e-03	101	65	3	DOID:1793 (is_marker_for)
Disease	unipolar depression, irritable bowel syndrome	PCLO NCAM1	1.74e-03	28	65	2	EFO_0000555, EFO_0003761
Disease	smoking status measurement, Cannabis use, schizophrenia	NCAM1 PHC2	1.87e-03	29	65	2	EFO_0006527, EFO_0007585, MONDO_0005090
Disease	Schizoaffective Disorder	NEUROG1 NPAS2	1.87e-03	29	65	2	C0036337
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	TULP4 NRXN2 UBAP2L NCAM1 NBEA ELL PHC2	1.88e-03	801	65	7	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	bowel opening frequency	MUC12 EYA1	2.00e-03	30	65	2	EFO_0600084
Disease	Marijuana Abuse	NCAM1 CHRM5	2.00e-03	30	65	2	C0024809
Disease	Major Depressive Disorder	ABI3BP PCLO NCAM1 CMYA5	2.05e-03	243	65	4	C1269683
Disease	joint hypermobility measurement	ABI3BP NEDD4	2.41e-03	33	65	2	EFO_0007905
Disease	Unipolar Depression	ABI3BP PCLO NCAM1 CMYA5	2.58e-03	259	65	4	C0041696
Disease	posterior thigh muscle fat infiltration measurement	EYA1 NPAS2	2.71e-03	35	65	2	EFO_0020934
Disease	bone mineral content measurement	EPHB3 DIP2C CMYA5	2.99e-03	130	65	3	EFO_0007621
Disease	hepatocyte growth factor-like protein measurement	NCKIPSD BSN	3.19e-03	38	65	2	EFO_0008154
Disease	prostate carcinoma	EPHB3 DIP2C AGAP7P PLEKHH2 BSN NEDD4 SOS1	3.40e-03	891	65	7	EFO_0001663
Disease	Abnormality of refraction	HIVEP3 TMEM72 PCLO PHRF1 NBEA NEDD4	3.64e-03	673	65	6	HP_0000539
Disease	smoking status measurement	SALL1 TULP4 NRXN2 UBAP2L NCAM1 ELL PHC2 SYNGAP1	3.86e-03	1160	65	8	EFO_0006527

Protein segments in the cluster

Peptide	Gene	Start	Entry
NYSDTPPTSKSTVEE	TWSG1	81	Q9GZX9
YSSSIPSTPSTSQED	AGAP4	191	Q96P64
VSSVPTSTSETPDYL	ELL	496	P55199
YSSSIPSTPSTSQED	AGAP6	191	Q5VW22
PVSSYAESETTDSVP	IRF2	226	P14316
VTDSPSPEYLKSDSD	NPAS2	151	Q99743
SSPYERIAPSESTTD	MUC16	3926	Q8WXI7
DTSTTFPTLSETPYE	MUC16	11556	Q8WXI7
STGDTTPLPVTDTYS	MUC4	2586	Q99102
EYPCSSEVSPSTESS	MAGEB5	21	Q9BZ81
PFSEESSSPVDEYTS	MAGEC1	866	O60732
ISDSSSYTFPPSDDT	NEDD4	186	P46934
LSDPSSPAASEDFTY	NEUROG1	196	Q92886
DSPDSDSSLSSPYST	HIPK1	941	Q86Z02
SGEYTPPAEETSSSQ	LMTK3	81	Q96Q04
SSCSEYSPSPSLDSE	BSN	1121	Q9UPA5
PELNSESEDYSPSSS	DCLK1	716	O15075
ESEDYSPSSSETVRS	DCLK1	721	O15075
YSEPSESATSVPPSD	PCLO	2166	Q9Y6V0
ETAYPSSPTSTVTES	MUC3A	1461	Q02505
SETPSETPTYEASLD	FAM221B	81	A6H8Z2
TDPTAEYSTIHSPST	EYA1	271	Q99502
EETTTPYPTEEEATE	NRP2	611	O60462
RSEVYDPSDPTGSDS	PHRF1	826	Q9P1Y6
RFLEDDPSDPTYTSS	EPHB3	781	P54753
YPSSDESSLETSPPD	NKX2-8	51	O15522
PDSYPTTPSSTDAAT	HUWE1	2741	Q7Z6Z7
DYSSSSSEANTPSPI	PLEKHH2	396	Q8IVE3
SDSSEDIYLDTPSSG	PPP1R3A	46	Q16821
DSSLPPTDDEDFYTT	NRXN2	456	P58401
PSESSSLSDTTTYDD	FRMD4B	576	Q9Y2L6
TKPRDTGPEDSYSSS	FRMD6	401	Q96NE9
SEPSADSYLTLSTAP	CEFIP	581	Q711Q0
TPDSTSASEYSVPSL	CMYA5	691	Q8N3K9
DAYTPPDTSSGSEDE	DIP2C	126	Q9Y2E4
YSSSIPSTPSTSQED	AGAP7P	191	Q5VUJ5
PESSYPTTATDDALE	CEP192	1046	Q8TEP8
SSVETYTPPDTSSAS	DIP2A	126	Q14689
YTPPDTSSASEDEGS	DIP2A	131	Q14689
EGSASPTSPDYSLDS	SASH3	106	O75995
TPVPDSYSESMESDT	SALL1	796	Q9NSC2
YLDSDDSSPLGSPST	MAP3K11	591	Q16584
SVLEADYSETPASSP	DRP2	696	Q13474
EDSVPSPLDTNYSTS	PRUNE2	956	Q8WUY3
PDTPSYPDTTSVSST	LRRC15	491	Q8TF66
TPCLAEPDSDSYSSS	ARHGAP42	611	A6NI28
EPDSDSYSSSPDSTP	ARHGAP42	616	A6NI28
SPESETDYPVSTDTR	NBEA	1011	Q8NFP9
LESSSSYNSETPSTP	MIIP	41	Q5JXC2
SDTTPDLDTTPYSST	SSC5D	1121	A1L4H1
YSISDRTSISDPPES	SOS1	1196	Q07889
TSLDTLYTSSSPSEP	NCKIPSD	221	Q9NZQ3
TTCSSYPSSEDEDKP	CHRM5	301	P08912
SSPSIDQVEPYSSTA	NCAM1	511	P13591
DSSESDTDSDDYAPP	TULP4	226	Q9NRJ4
YEEPLSPISASSSTS	PHC2	746	Q8IXK0
EPVLSDYESTPTTSA	UBAP2L	526	Q14157
DDTSSENTVVPPETY	RPA2	111	P15927
STSPFSSPITSDEEY	SPEG	816	Q15772
SSPAYCTSSSDITEP	SYNGAP1	816	Q96PV0
YSSEEPGPSSKDTAS	HIVEP3	601	Q5T1R4
YDTLPSDTVSLSDSD	TSSC4	21	Q9Y5U2
ESTPSTASLPSYDSV	SCN8A	1936	Q9UQD0
ETYQSPPFTETLDTS	SYNGR3	206	O43761
EEPSTTSTASNYPDV	NUP153	111	P49790
DSYSSLSPETESVNP	ZNF474	36	Q6S9Z5
PEQYTDPSSSAVSTT	TMEM72	146	A0PK05
RSPSSYSSDELSPGE	RAPGEFL1	121	Q9UHV5
TYDVFSSPTTSDEPE	ABI3BP	381	Q7Z7G0
SSPTTSDEPEISDSY	ABI3BP	386	Q7Z7G0
ETPTEVYPEPSTSTT	SON	311	P18583
SEPSAVPTDYSVSAS	SON	1221	P18583
PGLSEESTTVYSSSP	MUC12	2851	Q9UKN1