Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dihydrofolic acid binding	DHFR DHFR2	4.86e-05	3	81	2	GO:0051871
GeneOntologyMolecularFunction	dihydrofolate reductase activity	DHFR DHFR2	4.86e-05	3	81	2	GO:0004146
GeneOntologyMolecularFunction	kinase activity	IPPK CCNE1 PMS2P1 PIK3CD PI4KA PDPK1 FGFRL1 PRKG2 TEX14 TEK PSKH2	2.53e-04	764	81	11	GO:0016301
GeneOntologyBiologicalProcess	tetrahydrobiopterin metabolic process	DHFR DHFR2 PRKG2	6.61e-06	10	80	3	GO:0046146
GeneOntologyBiologicalProcess	response to methotrexate	DHFR DHFR2	4.45e-05	3	80	2	GO:0031427
GeneOntologyBiologicalProcess	glycine metabolic process	DHFR BAAT DHFR2	5.21e-05	19	80	3	GO:0006544
GeneOntologyBiologicalProcess	acyl-CoA metabolic process	ACACB BAAT ACSM5 GPAM HSD17B4	6.59e-05	109	80	5	GO:0006637
GeneOntologyBiologicalProcess	thioester metabolic process	ACACB BAAT ACSM5 GPAM HSD17B4	6.59e-05	109	80	5	GO:0035383
GeneOntologyBiologicalProcess	dihydrofolate metabolic process	DHFR DHFR2	8.87e-05	4	80	2	GO:0046452
GeneOntologyCellularComponent	endoplasmic reticulum tubular network membrane	ATL3 ATL1	1.44e-04	5	80	2	GO:0098826
HumanPheno	Colitis	TTC7A MYH11 DOCK11 PIK3CD PI4KA STAT1	4.58e-06	75	31	6	HP:0002583
HumanPheno	Autoimmune hemolytic anemia	TTC7A TPP2 DOCK11 PI4KA STAT1	6.13e-06	45	31	5	HP:0001890
HumanPheno	Inflammation of the large intestine	TTC7A MYH11 DOCK11 PIK3CD PI4KA STAT1	6.54e-05	119	31	6	HP:0002037
HumanPheno	Arthropathy	DOCK11 PIK3CD ATL3 ATL1 STAT4	9.20e-05	78	31	5	HP:0003040
HumanPheno	Congenital pulmonary airway malformation	TTC7A PI4KA	1.07e-04	3	31	2	HP:0010959
HumanPheno	Jejunoileal ulceration	TTC7A PI4KA	1.07e-04	3	31	2	HP:0005229
HumanPheno	Abnormal ileum morphology	TTC7A MYH11 DOCK11 PI4KA	1.17e-04	43	31	4	HP:0001549
HumanPheno	Abnormal ductus choledochus morphology	TTC7A PI4KA	2.13e-04	4	31	2	HP:0100889
HumanPheno	Impaired ability to dress oneself	ATL3 ATL1	2.13e-04	4	31	2	HP:0031060
HumanPheno	Enterocolitis	TTC7A MYH11 STAT1	2.17e-04	20	31	3	HP:0004387
HumanPheno	Acute colitis	TTC7A MYH11 STAT1	2.17e-04	20	31	3	HP:0100282
HumanPheno	Abnormal bronchus morphology	TPP2 MYH11 DOCK11 PIK3CD PI4KA SCNN1B STAT1	2.39e-04	215	31	7	HP:0025426
HumanPheno	Neutropenia in presence of anti-neutropil antibodies	TPP2 DOCK11 STAT1	2.91e-04	22	31	3	HP:0001904
HumanPheno	Abnormal metatarsal morphology	PIEZO2 PIK3CD ATL3 FGFRL1 PRKG2 STAT4	3.24e-04	159	31	6	HP:0001832
HumanPheno	Ileal atresia	TTC7A MYH11	3.54e-04	5	31	2	HP:0011102
HumanPheno	Trophic changes related to pain	ATL3 ATL1	3.54e-04	5	31	2	HP:0010834
HumanPheno	EMG: slow motor conduction	ATL3 ATL1	3.54e-04	5	31	2	HP:0100287
HumanPheno	Gastrointestinal inflammation	TTC7A MYH11 DOCK11 PIK3CD PI4KA STAT1	3.83e-04	164	31	6	HP:0004386
HumanPheno	Hemolytic anemia	TTC7A TPP2 DOCK11 PI4KA STAT1 STAT4	4.23e-04	167	31	6	HP:0001878
Domain	DHFR_dom	DHFR DHFR2	1.72e-05	2	78	2	IPR001796
Domain	DHFR_2	DHFR DHFR2	1.72e-05	2	78	2	PS51330
Domain	-	DHFR DHFR2	1.72e-05	2	78	2	3.40.430.10
Domain	DHFR_1	DHFR DHFR2	1.72e-05	2	78	2	PF00186
Domain	DHFR-like_dom	DHFR DHFR2	1.72e-05	2	78	2	IPR024072
Domain	DHFR_1	DHFR DHFR2	1.72e-05	2	78	2	PS00075
Domain	DHFR	DHFR DHFR2	1.72e-05	2	78	2	IPR012259
Domain	STAT_TF_prot_interaction	STAT1 STAT4	3.57e-04	7	78	2	IPR013799
Domain	STAT_TF_DNA-bd_sub	STAT1 STAT4	3.57e-04	7	78	2	IPR012345
Domain	STAT	STAT1 STAT4	3.57e-04	7	78	2	IPR001217
Domain	STAT_TF_coiled-coil	STAT1 STAT4	3.57e-04	7	78	2	IPR015988
Domain	-	STAT1 STAT4	3.57e-04	7	78	2	2.60.40.630
Domain	STAT_int	STAT1 STAT4	3.57e-04	7	78	2	SM00964
Domain	STAT_TF_DNA-bd	STAT1 STAT4	3.57e-04	7	78	2	IPR013801
Domain	STAT_bind	STAT1 STAT4	3.57e-04	7	78	2	PF02864
Domain	STAT_int	STAT1 STAT4	3.57e-04	7	78	2	PF02865
Domain	-	STAT1 STAT4	3.57e-04	7	78	2	1.10.532.10
Domain	STAT_alpha	STAT1 STAT4	3.57e-04	7	78	2	PF01017
Domain	-	STAT1 STAT4	3.57e-04	7	78	2	1.20.1050.20
Domain	STAT_TF_alpha	STAT1 STAT4	4.74e-04	8	78	2	IPR013800
Domain	PI3Ka	PIK3CD PI4KA	6.08e-04	9	78	2	PF00613
Domain	-	PIK3CD PI4KA	6.08e-04	9	78	2	1.25.40.70
Domain	PI3Ka	PIK3CD PI4KA	6.08e-04	9	78	2	SM00145
Domain	GBP_C	ATL3 ATL1	7.58e-04	10	78	2	PF02841
Domain	PIK_HELICAL	PIK3CD PI4KA	7.58e-04	10	78	2	PS51545
Domain	PI_Kinase	PIK3CD PI4KA	7.58e-04	10	78	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3CD PI4KA	7.58e-04	10	78	2	IPR001263
Domain	G_GB1_RHD3_dom	ATL3 ATL1	9.24e-04	11	78	2	IPR030386
Domain	Guanylate-bd_C	ATL3 ATL1	9.24e-04	11	78	2	IPR003191
Domain	GBP	ATL3 ATL1	9.24e-04	11	78	2	PF02263
Domain	Guanylate-bd_N	ATL3 ATL1	9.24e-04	11	78	2	IPR015894
Domain	G_GB1_RHD3	ATL3 ATL1	9.24e-04	11	78	2	PS51715
Domain	PI3/4_kinase_CS	PIK3CD PI4KA	1.75e-03	15	78	2	IPR018936
Domain	-	PIK3CD PI4KA	1.99e-03	16	78	2	1.10.1070.11
Domain	PI3Kc	PIK3CD PI4KA	1.99e-03	16	78	2	SM00146
Domain	PI3/4_kinase_cat_dom	PIK3CD PI4KA	2.52e-03	18	78	2	IPR000403
Domain	ZZ	MIB2 UTRN	2.52e-03	18	78	2	PF00569
Domain	PI3_PI4_kinase	PIK3CD PI4KA	2.52e-03	18	78	2	PF00454
Domain	PI3_4_KINASE_3	PIK3CD PI4KA	2.52e-03	18	78	2	PS50290
Domain	ZF_ZZ_2	MIB2 UTRN	2.52e-03	18	78	2	PS50135
Domain	PI3_4_KINASE_1	PIK3CD PI4KA	2.52e-03	18	78	2	PS00915
Domain	PI3_4_KINASE_2	PIK3CD PI4KA	2.52e-03	18	78	2	PS00916
Domain	ZF_ZZ_1	MIB2 UTRN	2.52e-03	18	78	2	PS01357
Domain	Znf_ZZ	MIB2 UTRN	2.81e-03	19	78	2	IPR000433
Domain	ZnF_ZZ	MIB2 UTRN	2.81e-03	19	78	2	SM00291
Domain	ARM-type_fold	DOCK11 PIK3CD PI4KA NCBP1 NUP188 FMNL2	2.93e-03	339	78	6	IPR016024
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ABLIM1 COX5A PI4KA PES1 NCBP1 NUP214 NUP188 SSRP1 HSD17B4 UTRN GTF3C5 STAT1 EFTUD2	7.89e-07	1024	82	13	24711643
Pubmed	Target gene specificity of E2F and pocket protein family members in living cells.	CCNE1 DHFR DHFR2	2.74e-06	12	82	3	10913163
Pubmed	Fanconi anemia core complex gene promoters harbor conserved transcription regulatory elements.	STAT1 STAT4	5.49e-06	2	82	2	21826217
Pubmed	Tyrosine phosphorylation regulates the partitioning of STAT1 between different dimer conformations.	STAT1 STAT4	5.49e-06	2	82	2	18591661
Pubmed	Contactin associates with Na+ channels and increases their functional expression.	SCNN1B CNTN1	5.49e-06	2	82	2	11567041
Pubmed	The Ets transcription factor ERM is Th1-specific and induced by IL-12 through a Stat4-dependent pathway.	STAT1 STAT4	5.49e-06	2	82	2	10097133
Pubmed	High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.	STAT1 STAT4	5.49e-06	2	82	2	19333953
Pubmed	Polymorphisms of signal transducers and activators of transcription 1 and 4 (STAT1 and STAT4) contribute to progression of childhood IgA nephropathy.	STAT1 STAT4	5.49e-06	2	82	2	20045654
Pubmed	STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.	STAT1 STAT4	5.49e-06	2	82	2	24920804
Pubmed	cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.	STAT1 STAT4	5.49e-06	2	82	2	9284918
Pubmed	Disease Risk-Associated Genetic Variants in STAT1 and STAT4 Function in a Complementary Manner to Increase Pattern-Recognition Receptor-Induced Outcomes in Human Macrophages.	STAT1 STAT4	5.49e-06	2	82	2	32661180
Pubmed	Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region.	STAT1 STAT4	5.49e-06	2	82	2	18803832
Pubmed	Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function.	STAT1 STAT4	5.49e-06	2	82	2	22968462
Pubmed	Crystal structure of a tyrosine phosphorylated STAT-1 dimer bound to DNA.	STAT1 STAT4	5.49e-06	2	82	2	9630226
Pubmed	Haplotypes of the Mutated SIRT2 Promoter Contributing to Transcription Factor Binding and Type 2 Diabetes Susceptibility.	SIRT2 STAT1	5.49e-06	2	82	2	32438712
Pubmed	Actin dynamics regulation by TTC7A/PI4KIIIα limits DNA damage and cell death under confinement.	TTC7A PI4KA	5.49e-06	2	82	2	37390900
Pubmed	Epigenetic control of innate and adaptive immune memory.	STAT1 STAT4	5.49e-06	2	82	2	30082830
Pubmed	Cell proliferation in the absence of E2F1-3.	CCNE1 DHFR DHFR2	6.92e-06	16	82	3	21185283
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	TTC7A ABLIM1 MRTFB PI4KA NUP214 FMNL2 UTRN STAT1 MPP7	7.56e-06	565	82	9	25468996
Pubmed	Translocation of a long amino-terminal domain through ER membrane by following signal-anchor sequence.	DHFR DHFR2	1.64e-05	3	82	2	16107879
Pubmed	Assignment of two rat dihydrofolate (DHFR) genes to chromosomes 2 and 4.	DHFR DHFR2	1.64e-05	3	82	2	2323224
Pubmed	Dihydrofolate reductase deficiency causing megaloblastic anemia in two families.	DHFR DHFR2	1.64e-05	3	82	2	1060915
Pubmed	IL-21 promotes differentiation of naive CD8 T cells to a unique effector phenotype.	STAT1 STAT4	1.64e-05	3	82	2	17548600
Pubmed	New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13.	DHFR DHFR2	1.64e-05	3	82	2	8903722
Pubmed	An active second dihydrofolate reductase enzyme is not a feature of rat and mouse, but they do have activity in their mitochondria.	DHFR DHFR2	1.64e-05	3	82	2	25980602
Pubmed	Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells.	DHFR DHFR2	1.64e-05	3	82	2	2263462
Pubmed	The role of Tyk2, Stat1 and Stat4 in LPS-induced endotoxin signals.	STAT1 STAT4	1.64e-05	3	82	2	15226272
Pubmed	Isolation and expression of an altered mouse dihydrofolate reductase cDNA.	DHFR DHFR2	1.64e-05	3	82	2	6573667
Pubmed	Germ line activation of the Tie2 and SMMHC promoters causes noncell-specific deletion of floxed alleles.	MYH11 TEK	1.64e-05	3	82	2	18612081
Pubmed	Expression and amplification of engineered mouse dihydrofolate reductase minigenes.	DHFR DHFR2	1.64e-05	3	82	2	6835212
Pubmed	Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.	DHFR DHFR2	1.64e-05	3	82	2	26830229
Pubmed	Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria.	DHFR DHFR2	1.64e-05	3	82	2	22993211
Pubmed	New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.	DHFR DHFR2	1.64e-05	3	82	2	17019704
Pubmed	Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.	DHFR DHFR2	1.64e-05	3	82	2	21402147
Pubmed	Unbalanced growth in mouse cells with amplified dhfr genes.	DHFR DHFR2	1.64e-05	3	82	2	9650531
Pubmed	Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo.	STAT1 STAT4	1.64e-05	3	82	2	34795671
Pubmed	Structure and genomic organization of the mouse dihydrofolate reductase gene.	DHFR DHFR2	1.64e-05	3	82	2	6244105
Pubmed	Stat3 and Stat4: members of the family of signal transducers and activators of transcription.	STAT1 STAT4	1.64e-05	3	82	2	7545930
Pubmed	Candidate genes for COPD in two large data sets.	SIRT2 STAT1	1.64e-05	3	82	2	20562129
Pubmed	Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.	DHFR DHFR2	1.64e-05	3	82	2	9357973
Pubmed	Phenotypic expression in E. coli of a DNA sequence coding for mouse dihydrofolate reductase.	DHFR DHFR2	1.64e-05	3	82	2	360074
Pubmed	Human atlastin GTPases mediate differentiated fusion of endoplasmic reticulum membranes.	ATL3 ATL1	1.64e-05	3	82	2	25773277
Pubmed	Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha.	STAT1 STAT4	1.64e-05	3	82	2	17015705
Pubmed	Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.	SIRT2 STAT1	1.64e-05	3	82	2	30487288
Pubmed	Gene amplification and drug resistance in cultured murine cells.	DHFR DHFR2	1.64e-05	3	82	2	715457
Pubmed	Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.	DHFR DHFR2	1.64e-05	3	82	2	627542
Pubmed	Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.	DHFR DHFR2	1.64e-05	3	82	2	6282858
Pubmed	In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application.	DHFR DHFR2	1.64e-05	3	82	2	9554740
Pubmed	The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.	DHFR DHFR2	1.64e-05	3	82	2	1545788
Pubmed	Relation of folic acid reductase to amethopterin resistance in cultured mammalian cells.	DHFR DHFR2	1.64e-05	3	82	2	13710631
Pubmed	Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction.	DHFR DHFR2	1.64e-05	3	82	2	30954686
Pubmed	Assignment of the human dihydrofolate reductase gene to the q11----q22 region of chromosome 5.	DHFR DHFR2	1.64e-05	3	82	2	6504041
Pubmed	Influence of substrate binding on the mechanical stability of mouse dihydrofolate reductase.	DHFR DHFR2	1.64e-05	3	82	2	16183885
Pubmed	The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional.	DHFR DHFR2	1.64e-05	3	82	2	21876184
Pubmed	Mammalian knock out cells reveal prominent roles for atlastin GTPases in ER network morphology.	ATL3 ATL1	1.64e-05	3	82	2	27669642
Pubmed	Nucleotide sequence surrounding multiple polyadenylation sites in the mouse dihydrofolate reductase gene.	DHFR DHFR2	1.64e-05	3	82	2	6121807
Pubmed	Transcriptional regulation of the dihydrofolate reductase/rep-3 locus.	DHFR DHFR2	1.64e-05	3	82	2	7987046
Pubmed	The amino acid sequence of dihydrofolate reductase from the mouse lymphoma L1210.	DHFR DHFR2	1.64e-05	3	82	2	762074
Pubmed	Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids.	DHFR DHFR2	1.64e-05	3	82	2	6272123
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ADSS2 PI4KA PCLO PES1 NCBP1 NOL10 NUP214 NUP188 SSRP1 HSD17B4 GTF3C5 STAT1 EFTUD2	2.79e-05	1425	82	13	30948266
Pubmed	Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation.	STAT1 STAT4	3.28e-05	4	82	2	17018853
Pubmed	STATs as activators of apoptosis.	STAT1 STAT4	3.28e-05	4	82	2	9695817
Pubmed	Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6.	STAT1 STAT4	3.28e-05	4	82	2	8140422
Pubmed	Endothelial Nitric Oxide Synthase-Derived Nitric Oxide Prevents Dihydrofolate Reductase Degradation via Promoting S-Nitrosylation.	DHFR DHFR2	3.28e-05	4	82	2	26381869
Pubmed	Assignment of genes encoding dihydrofolate reductase and hexosaminidase B to Mus musculus chromosome 13.	DHFR DHFR2	3.28e-05	4	82	2	2947337
Pubmed	Heterogeneity at the 5' termini of mouse dihydrofolate reductase mRNAs. Evidence for multiple promoter regions.	DHFR DHFR2	3.28e-05	4	82	2	2982814
Pubmed	IL-23 drives pathogenic IL-17-producing CD8+ T cells.	STAT1 STAT4	3.28e-05	4	82	2	19380776
Pubmed	Characterization and chromosome location of the mouse link protein gene (Crtl1).	DHFR DHFR2	3.28e-05	4	82	2	10640815
Pubmed	Analysis of the mouse Dhfr/Rep-3 major promoter region by using linker-scanning and internal deletion mutations and DNase I footprinting.	DHFR DHFR2	3.28e-05	4	82	2	2233729
Pubmed	STATs and gene regulation.	STAT1 STAT4	3.28e-05	4	82	2	9287210
Pubmed	The functional human dihydrofolate reductase gene.	DHFR DHFR2	3.28e-05	4	82	2	6323448
Pubmed	Isolation and characterization of cDNA clones derived from the divergently transcribed gene in the region upstream from the human dihydrofolate reductase gene.	DHFR DHFR2	3.28e-05	4	82	2	2722860
Pubmed	Transcription factor p73 regulates Th1 differentiation.	STAT1 STAT4	3.28e-05	4	82	2	32193462
Pubmed	IL9 maps to mouse chromosome 13 and human chromosome 5.	DHFR DHFR2	3.28e-05	4	82	2	1970335
Pubmed	IL-27 limits IL-2 production during Th1 differentiation.	STAT1 STAT4	3.28e-05	4	82	2	16365415
Pubmed	Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.	DHFR DHFR2	3.28e-05	4	82	2	20424322
Pubmed	Dual bidirectional promoters at the mouse dhfr locus: cloning and characterization of two mRNA classes of the divergently transcribed Rep-1 gene.	DHFR DHFR2	3.28e-05	4	82	2	2674679
Pubmed	Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program.	STAT1 STAT4	3.28e-05	4	82	2	24489092
Pubmed	Cell adhesion to substratum and activation of tyrosine kinases are essentially required for G1/S phase transition in BALB/c 3T3 fibroblasts.	DHFR DHFR2	3.28e-05	4	82	2	8611632
Pubmed	STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production.	TEK STAT1	3.28e-05	4	82	2	23086340
Pubmed	Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression.	TEK STAT1	3.28e-05	4	82	2	18401423
Pubmed	Protein unfolding and degradation by the AAA+ Lon protease.	DHFR DHFR2	3.28e-05	4	82	2	22162032
Pubmed	Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin.	SCNN1B CNTN1	3.28e-05	4	82	2	14761957
Pubmed	A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3.	STAT1 STAT4	3.28e-05	4	82	2	12426389
Pubmed	Inhibition of Th1 development mediated by GATA-3 through an IL-4-independent mechanism.	STAT1 STAT4	3.28e-05	4	82	2	9846495
Pubmed	Graft rejection as a Th1-type process amenable to regulation by donor Th2-type cells through an interleukin-4/STAT6 pathway.	STAT1 STAT4	3.28e-05	4	82	2	18625883
Pubmed	T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells.	STAT1 STAT4	3.28e-05	4	82	2	12006974
Pubmed	Position-dependent transcriptional regulation of the murine dihydrofolate reductase promoter by the E2F transactivation domain.	DHFR DHFR2	3.28e-05	4	82	2	9121444
Pubmed	High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells.	STAT1 STAT4	5.47e-05	5	82	2	17846149
Pubmed	Endothelial NOX4 aggravates eNOS uncoupling by decreasing dihydrofolate reductase after subarachnoid hemorrhage.	DHFR DHFR2	5.47e-05	5	82	2	36336227
Pubmed	Regulation of epithelial sodium channels by cGMP/PKGII.	SCNN1B PRKG2	5.47e-05	5	82	2	19359370
Pubmed	Beta-glycoglycosphingolipid-induced alterations of the STAT signaling pathways are dependent on CD1d and the lipid raft protein flotillin-2.	STAT1 STAT4	5.47e-05	5	82	2	19246642
Pubmed	Endothelial retinoblastoma protein reduces abdominal aortic aneurysm development via promoting DHFR/NO pathway-mediated vasoprotection.	DHFR DHFR2	5.47e-05	5	82	2	31214845
Pubmed	Decoupling of DNA excision repair and RNA transcription in translocation breaksite regions of plasmacytoma-susceptible BALB/cAnPt mice.	DHFR DHFR2	5.47e-05	5	82	2	9111201
Pubmed	Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network.	ATL3 ATL1	5.47e-05	5	82	2	27619977
Pubmed	Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.	DHFR DHFR2	5.47e-05	5	82	2	19666465
Pubmed	T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells.	STAT1 STAT4	5.47e-05	5	82	2	33603753
Pubmed	The response of autologous T cells to a human melanoma is dominated by mutated neoantigens.	SIRT2 EFTUD2	5.47e-05	5	82	2	16247014
Pubmed	Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation.	STAT1 STAT4	5.47e-05	5	82	2	35148827
Pubmed	Immunohistochemical analysis of the expression of cellular transcription NFκB (p65), AP-1 (c-Fos and c-Jun), and JAK/STAT in leprosy.	STAT1 STAT4	5.47e-05	5	82	2	25771902
Cytoband	10q25	ABLIM1 SLC18A2	1.72e-04	11	82	2	10q25
Cytoband	9q34.1	NCBP1 NUP214	5.28e-04	19	82	2	9q34.1
Cytoband	Ensembl 112 genes in cytogenetic band chr10q25	ABLIM1 SLC18A2 GPAM	1.71e-03	131	82	3	chr10q25
Cytoband	Ensembl 112 genes in cytogenetic band chr2p15	PUS10 B3GNT2	2.84e-03	44	82	2	chr2p15
Cytoband	Ensembl 112 genes in cytogenetic band chr13q33	TPP2 POGLUT2	4.40e-03	55	82	2	chr13q33
Cytoband	1p36.21	PRAMEF33 PRAMEF10	5.74e-03	63	82	2	1p36.21
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	MIB2 UTRN	9.85e-04	18	47	2	91
GeneFamily	General transcription factors\|Xeroderma pigmentosum complementation groups\|DNA helicases\|ERCC excision repair associated	GTF2H1 GTF3C5	1.91e-03	25	47	2	565
GeneFamily	Nucleoporins	NUP214 NUP188	3.12e-03	32	47	2	1051
GeneFamily	PDZ domain containing	PCLO PARD3B MPP7	7.21e-03	152	47	3	1220
GeneFamily	Fibronectin type III domain containing	TEK CNTN1 SORL1	8.29e-03	160	47	3	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	UNC5A FGFRL1 CNTN1	8.44e-03	161	47	3	593
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPPK PIK3CD KLHL35 MAD2L1BP STAT1 STAT4	7.10e-07	169	82	6	573f85075d83a4baba41c3e24dc4d9831823a5e5
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IPPK PIK3CD KLHL35 MAD2L1BP STAT1 STAT4	7.10e-07	169	82	6	a24d12199b1a6d9cb243b3a68f4109d3a30b2dcb
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	SIRT2 ZNF26 TMEM232 MIB2 FMNL2 SORL1	8.71e-07	175	82	6	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 ABLIM1 PIK3CD STAT4 MPP7 SORL1	1.03e-06	180	82	6	dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCell	LPS_only-Lymphocytic_NKT-T_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 ABLIM1 PIK3CD STAT4 MPP7 SORL1	1.06e-06	181	82	6	a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCell	Secretory\|World / shred by cell class for bronchial biopsy	ABLIM1 PARD3B ANKRD36C CNTN1 MSLN SORL1	1.63e-06	195	82	6	52f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IPPK ABLIM1 PIEZO2 RGS9 TEK	1.03e-05	156	82	5	1928c86deb3bcd01db4ae76919a351066aadb39a
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABLIM1 PIEZO2 DHFR RGS9 TEK	1.90e-05	177	82	5	0e74980a7686c31fcf1476b8f19a3392541df240
ToppCell	LPS-IL1RA-Lymphocytic_NKT\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 RGS9 STAT4 MPP7 SORL1	2.01e-05	179	82	5	5ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABLIM1 MRTFB ACACB TEK UTRN	2.01e-05	179	82	5	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SETMAR SLC18A2 GLB1L PARD3B TEK	2.12e-05	181	82	5	a53f05c4c47465ee62e353716456bd09ab464b23
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	UNC5A SCNN1B PARD3B MSLN SORL1	2.17e-05	182	82	5	94e70746e35a3062015d4b83ee545f4f84f47420
ToppCell	LPS_only-Lymphocytic_NKT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 PIK3CD STAT4 MPP7 SORL1	2.54e-05	188	82	5	bbe65b1c11c88ab62d8485cfc3a913ff9da89aad
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERAP2 SLC18A2 PIK3CD STAT4 SORL1	2.67e-05	190	82	5	2a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 ABLIM1 PIK3CD STAT4 SORL1	2.74e-05	191	82	5	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 ABLIM1 PIK3CD STAT4 SORL1	2.81e-05	192	82	5	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TMTC3 GARIN1B ANKRD36C UTRN STAT4	2.88e-05	193	82	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	COVID-19-kidney-T-cells-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCNX2 DOCK11 PIK3CD STAT4 SORL1	2.88e-05	193	82	5	5b84fa640cf30dea55fde53b810f850ff946d253
ToppCell	Control_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK11 PIK3CD RGS9 STAT4 SORL1	3.25e-05	198	82	5	9663cf0c8296d3a7b0329cb725ccceeea7849cbc
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	ABLIM1 PARD3B TEX14 STAT1 SORL1	3.25e-05	198	82	5	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	Control_saline-Hematopoietic_Lymphocytic-Lymphocytic_NK/T-iNKT-MAIT\|Control_saline / Treatment groups by lineage, cell group, cell type	DOCK11 PIK3CD RGS9 STAT4 SORL1	3.33e-05	199	82	5	2d7ebb9642f6fe0afd5e3fdc711ded54b73acd11
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	ACSM5 PARD3B GPAM RGS9	1.10e-04	134	82	4	2647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SETMAR GLB1L RGS9 STAT4	1.30e-04	140	82	4	a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 CASQ1 STAT4 CNTN1	2.12e-04	159	82	4	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	droplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD GLB1L KLHL35 MIB2	2.17e-04	160	82	4	a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGFRL1 GPAM ALDH3B2 CNTN1	2.33e-04	163	82	4	1eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM232 LRRC43 DNAH6 CNTN1	2.39e-04	164	82	4	d9531848105d606adedde65426177cf851140e31
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BAAT GPX2 SCNN1B ALDH3B2	2.44e-04	165	82	4	6fdce8b23736409a23884ef3918638ffc067a86f
ToppCell	facs-Kidney-nan-3m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 DOCK11 ADAM30 STAT4	2.44e-04	165	82	4	ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BAAT GPX2 SCNN1B ALDH3B2	2.44e-04	165	82	4	dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BAAT GPX2 SCNN1B ALDH3B2	2.44e-04	165	82	4	baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 GLB1L NCBP1 CNTN1	2.56e-04	167	82	4	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNE1 DHFR SSRP1 CNTN1	2.56e-04	167	82	4	859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 GLB1L NCBP1 CNTN1	2.56e-04	167	82	4	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIEZO2 GLB1L NCBP1 CNTN1	2.56e-04	167	82	4	eff3723fe60755272eca237459165e436e919ece
ToppCell	CV-Mild-6\|CV / Virus stimulation, Condition and Cluster	SIRT2 ZNF26 TMEM232 SORL1	2.56e-04	167	82	4	cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)\|368C / Donor, Lineage, Cell class and subclass (all cells)	UNC5A PIEZO2 SCNN1B MPP7	2.61e-04	168	82	4	a74c8a9e3299183fba31ce3053ef325b5dbcd104
ToppCell	368C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	UNC5A PIEZO2 SCNN1B MPP7	2.61e-04	168	82	4	dae37b316ce80dfe4236c4ed7f0d4e7c340fa7b6
ToppCell	368C-Lymphocytic-ILC\|368C / Donor, Lineage, Cell class and subclass (all cells)	MYH11 PDPK1 DHFR2 MPP7	2.80e-04	171	82	4	3b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	2.80e-04	171	82	4	539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCell	368C-Lymphocytic-ILC-ILC-2\|368C / Donor, Lineage, Cell class and subclass (all cells)	MYH11 PDPK1 DHFR2 MPP7	2.80e-04	171	82	4	fd01076574dcc82bfd4a1538812500543b16794f
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	ACACB GLB1L LRRC43 DNAH6	2.80e-04	171	82	4	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	2.86e-04	172	82	4	0fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCell	facs-Lung-nan-3m-Lymphocytic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 DOCK11 PIK3CD STAT4	2.86e-04	172	82	4	7af0713c40ea48f1e92c859c4fc4d8f0137c4415
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM232 GARIN1B LRRC43 DNAH6	2.92e-04	173	82	4	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KLHL35 PRKG2 TEX14 MSLN	2.99e-04	174	82	4	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 PCLO DNAH6 MPP7	3.05e-04	175	82	4	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	3.12e-04	176	82	4	9d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCNN1B FGFRL1 RGS9 ATL1	3.12e-04	176	82	4	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	3.12e-04	176	82	4	bb41e9478373726eb460af764de0277b2d09928e
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	3.12e-04	176	82	4	ea27e18407b8a13e8212830da859efeb8f158690
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	3.12e-04	176	82	4	bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	TMEM232 GARIN1B LRRC43 DNAH6	3.19e-04	177	82	4	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	UNC5A PCLO SCNN1B MPP7	3.33e-04	179	82	4	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABLIM1 SCNN1B PRKG2 MSLN	3.33e-04	179	82	4	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	LPS-antiTNF-Lymphocytic_NKT\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCNX2 STAT4 MPP7 SORL1	3.33e-04	179	82	4	ecea75c568911ff56939c9f67ab901497bd4356c
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ABLIM1 GPX2 RGS9 POGLUT2	3.33e-04	179	82	4	bc95c3e7edc5fc6fc913b09f087d221df64c6f48
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	UNC5A PCLO SCNN1B MPP7	3.33e-04	179	82	4	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ERAP2 PRKG2 STAT4 SORL1	3.33e-04	179	82	4	db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	UNC5A PCLO SCNN1B MPP7	3.47e-04	181	82	4	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	UNC5A PCLO SCNN1B MPP7	3.47e-04	181	82	4	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 SENP6 UTRN STAT4	3.54e-04	182	82	4	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 SENP6 UTRN STAT4	3.54e-04	182	82	4	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5A PIEZO2 UTRN MPP7	3.54e-04	182	82	4	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRTFB SLC18A2 TEK UTRN	3.54e-04	182	82	4	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5A PIEZO2 UTRN MPP7	3.54e-04	182	82	4	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRTFB SLC18A2 TEK UTRN	3.54e-04	182	82	4	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PUS10 PCLO FGFRL1 POGLUT2	3.54e-04	182	82	4	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UNC5A PIEZO2 UTRN MPP7	3.54e-04	182	82	4	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	droplet-Liver-Npc-21m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLB1L FMNL2 STAT4	3.58e-04	75	82	3	7f3be37cc378ee115fcb4b0eb9653fc77447aa0a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRTFB SLC18A2 TEK UTRN	3.69e-04	184	82	4	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABLIM1 SCNN1B PARD3B UTRN	3.69e-04	184	82	4	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABLIM1 SCNN1B PRKG2 MSLN	3.69e-04	184	82	4	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	MRTFB DOCK11 TEK UTRN	3.69e-04	184	82	4	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 PIK3CD STAT4 SORL1	3.69e-04	184	82	4	5cf7447faaec99fc37dfa8e92ff72cc2c7c05951
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 PIK3CD STAT4 SORL1	3.69e-04	184	82	4	7126261a453c7e2f3f005016873b6adeb51e46f8
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABLIM1 SCNN1B PARD3B UTRN	3.69e-04	184	82	4	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	UNC5A PIEZO2 TEK MPP7	3.77e-04	185	82	4	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ACACB PDPK1 PARD3B GPAM	3.77e-04	185	82	4	1d874608aa2062024323512f68889219471b2f00
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	UNC5A PIEZO2 TEK MPP7	3.77e-04	185	82	4	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC18A2 GPX2 DNAH6 MSLN	3.85e-04	186	82	4	29c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3CD STAT4 MPP7 SORL1	3.85e-04	186	82	4	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	droplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRTFB SLC18A2 TEK UTRN	3.85e-04	186	82	4	5d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 PIK3CD UTRN STAT4	3.85e-04	186	82	4	4dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 MRTFB TEK UTRN	3.85e-04	186	82	4	ba6ba75218efc26371cea24ddbb0e9b3e3f421ac
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC18A2 DPP8 TEK UTRN	3.85e-04	186	82	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	facs-Trachea-nan-24m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX2 SCNN1B ALDH3B2 MSLN	3.85e-04	186	82	4	6c06163d7315f1c71b15fe76f2e696bf3fa73b67
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCNE1 MYH11 TEX14 CNTN1	3.85e-04	186	82	4	26458ff8cad5577de4306cffa0ca69eb26940e0d
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCNE1 MYH11 TEX14 CNTN1	3.85e-04	186	82	4	a71397efc68d2916ddc373d92cfd07be58033e1c
ToppCell	facs-Trachea-nan-24m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX2 SCNN1B ALDH3B2 MSLN	3.85e-04	186	82	4	78e3b00eb347d1aa197671e31be9b0c6e4235760
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 MRTFB TEK UTRN	3.85e-04	186	82	4	65e25a9dcef5fc71510aaf170e220deef5b2feb2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 MRTFB TEK UTRN	3.85e-04	186	82	4	e4f1259725160719e5fd13d76e5a707efed70013
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 PIK3CD UTRN STAT4	3.85e-04	186	82	4	e23e1246914e230369a716d0d666b98383bf8512
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB COX5A DHFR SORL1	3.92e-04	187	82	4	52b5b38bef3cc06487cf42c6fb22fb33f0c7ce2b
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PCNX2 PIK3CD STAT4 SORL1	4.09e-04	189	82	4	df30478b288084a1bd48f660409dcc784040897c
ToppCell	droplet-Lung-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM232 GPX2 LRRC43 DNAH6	4.09e-04	189	82	4	fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ACACB FMNL2 UTRN MPP7	4.17e-04	190	82	4	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	LAM-Epithelial-AT1\|Epithelial / Condition, Lineage and Cell class	ABLIM1 BAAT SCNN1B MSLN	4.25e-04	191	82	4	3457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABLIM1 ANKRD36C STAT4 SORL1	4.25e-04	191	82	4	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	COVID-19-lung-CD4+_Treg\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCNX2 PIK3CD STAT4 SORL1	4.25e-04	191	82	4	5a4ad5ae5c2dbfb225158cb598ef649c26a48350
Drug	S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (6R)-6-[(3R,5S,7R,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-5,10,13-trimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-3-oxoheptanethioate	BAAT HSD17B4	1.22e-05	2	80	2	CID011966185
Drug	NSC-107146	DHFR DHFR2	1.22e-05	2	80	2	CID000267616
Drug	3'-fluoroaminopterin	DHFR DHFR2	1.22e-05	2	80	2	CID000128780
Drug	DIVEMA-MTX	DHFR DHFR2	1.22e-05	2	80	2	CID000430857
Drug	gamma-tBAMT	DHFR DHFR2	1.22e-05	2	80	2	CID000125341
Drug	4-ethylacetophenone	DHFR DHFR2	1.22e-05	2	80	2	CID000013642
Drug	aditoprim	DHFR DHFR2	1.22e-05	2	80	2	CID000068755
Drug	2,4-diamino-5-benzylpyrimidine	DHFR DHFR2	1.22e-05	2	80	2	CID000081752
Drug	2,4-diamino-5-phenylpyrimidine	DHFR DHFR2	1.22e-05	2	80	2	CID000134761
Drug	methotrexate-alpha-aspartate	DHFR DHFR2	1.22e-05	2	80	2	CID000100376
Drug	ethyl isocyanatoacetate	DHFR DHFR2	1.22e-05	2	80	2	CID000076283
Drug	S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (6R)-2-methyl-3-oxo-6-[(3R,5S,7R,8R,9S,10R,12S,13R,14S,17R)-3,7,12-trihydroxy-5,10,13-trimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]heptanethioate	BAAT HSD17B4	3.65e-05	3	80	2	CID011966186
Drug	2,4,5,6-Tetraaminopyrimidine sulfate	DHFR DHFR2	3.65e-05	3	80	2	CID000070487
Drug	GNF-Pf-26	DHFR DHFR2	3.65e-05	3	80	2	CID000093114
Drug	diaveridine	DHFR DHFR2	3.65e-05	3	80	2	CID000021453
Drug	I--254	DHFR DHFR2	3.65e-05	3	80	2	CID000032285
Drug	8-deazahomofolic acid	DHFR DHFR2	3.65e-05	3	80	2	CID000130665
Drug	chloroformamidine hydrochloride	DHFR DHFR2	3.65e-05	3	80	2	CID003084509
Drug	chloromethyl pivalate	DHFR DHFR2	3.65e-05	3	80	2	CID000087885
Drug	DMDP derivative	DHFR DHFR2	3.65e-05	3	80	2	CID000482165
Drug	MTX-gamma-DMPE	DHFR DHFR2	3.65e-05	3	80	2	CID000146936
Drug	dihydropteroylhexaglutamate	DHFR DHFR2	3.65e-05	3	80	2	CID000193840
Drug	F2Glu	DHFR DHFR2	3.65e-05	3	80	2	CID000125424
Drug	Pirenperone [ 75444-65-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A	ACACB PIK3CD GLB1L NUP214 NUP188 UTRN	6.86e-05	197	80	6	3316_UP
Drug	SN-429	COX5A CNTN1	7.28e-05	4	80	2	CID009869498
Drug	ethyl 4-acetylbenzoate	DHFR DHFR2	7.28e-05	4	80	2	CID000600911
Drug	pY490	DHFR DHFR2	7.28e-05	4	80	2	CID000283017
Drug	K 130	DHFR DHFR2	7.28e-05	4	80	2	CID000467834
Drug	5-deazaaminopterin	DHFR DHFR2	7.28e-05	4	80	2	CID000097272
Drug	2,4-diamino-6-nitroquinazoline	DHFR DHFR2	7.28e-05	4	80	2	CID000252163
Drug	AC1MQVYC	DHFR DHFR2	7.28e-05	4	80	2	CID003483303
Drug	methasquin	DHFR DHFR2	7.28e-05	4	80	2	CID000029335
Drug	pergularinine	DHFR DHFR2	7.28e-05	4	80	2	CID000264751
Drug	5,8-dideazafolic acid	DHFR DHFR2	7.28e-05	4	80	2	CID003080619
Drug	H-Mn	PES1 STAT1 ATL1 EFTUD2	1.15e-04	71	80	4	CID000445522
Drug	2-desamino-2-methylaminopterin	DHFR DHFR2	1.21e-04	5	80	2	CID000164085
Drug	tylophorinidine	DHFR DHFR2	1.21e-04	5	80	2	CID000161749
Drug	deoxytubulosine	DHFR DHFR2	1.21e-04	5	80	2	CID000165003
Drug	dansylglutamylglycylarginyl chloromethyl ester	COX5A CNTN1	1.21e-04	5	80	2	CID003081184
Drug	piritrexim isethionate	DHFR DHFR2	1.21e-04	5	80	2	CID000054368
Drug	chlorasquin	DHFR DHFR2	1.21e-04	5	80	2	CID000029336
Drug	methylbenzoprim	DHFR DHFR2	1.21e-04	5	80	2	CID000072438
Drug	ZD9331	CCNE1 DHFR DHFR2	1.28e-04	28	80	3	CID000213022
Drug	5'-GMP Na2	GTF2H1 ADSS2 PRKG2 UTRN STAT1 ATL1 MPP7	1.78e-04	335	80	7	CID000000761
Drug	NBMPR-P	DHFR DHFR2	1.81e-04	6	80	2	CID006335125
Drug	4-thio-5-fluoro-dUMP	DHFR DHFR2	1.81e-04	6	80	2	CID003035986
Drug	11-deazahomofolic acid	DHFR DHFR2	1.81e-04	6	80	2	CID000128960
Drug	10-methyl-11-deazahomofolic acid	DHFR DHFR2	1.81e-04	6	80	2	CID000128963
Drug	II 19	DHFR DPP8	1.81e-04	6	80	2	CID000040321
Disease	Gastrointestinal defect and immunodeficiency syndrome	TTC7A PI4KA	6.55e-06	2	76	2	cv:C5234880
Disease	hereditary spastic paraplegia 3A (implicated_via_orthology)	ATL3 ATL1	1.96e-05	3	76	2	DOID:0110791 (implicated_via_orthology)
Disease	Combined immunodeficiency	TTC7A PIK3CD STAT1	1.63e-04	41	76	3	C0494261
Disease	Hereditary Sensory Autonomic Neuropathy, Type 1	ATL3 ATL1	1.81e-04	8	76	2	C0020071
Disease	2-hydroxystearate measurement	TEK CNTN1	2.33e-04	9	76	2	EFO_0021059
Disease	Malignant neoplasm of breast	CCNE1 PDPK1 DHFR GPX2 SCNN1B NUP214 TEK STAT1 STAT4 SORL1	4.23e-04	1074	76	10	C0006142
Disease	serum metabolite measurement	CCNE1 GTF2H1 ERAP2 SLC18A2 PARD3B GPAM ALDH3B2 TEK ATL1	7.12e-04	945	76	9	EFO_0005653
Disease	Rheumatoid Arthritis	B3GNT2 DHFR STAT1 STAT4	1.08e-03	174	76	4	C0003873
Disease	Bronchiectasis	PIK3CD SCNN1B	1.46e-03	22	76	2	C0006267
Disease	JT interval, response to sulfonylurea	HSD17B4 STAT1	1.60e-03	23	76	2	EFO_0007885, EFO_0007922
Disease	chronic obstructive pulmonary disease (biomarker_via_orthology)	STAT1 STAT4	2.37e-03	28	76	2	DOID:3083 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LYPAPLESLDYKGHV	PRAMEF33	411	A0A0G2JMD5
LAYHNYEDLPRKPEV	BAAT	191	Q14032
IYRKPPIYKQHAALA	ABLIM1	521	O14639
KLEEIYPPKLHQFAY	CCNE1	201	P24864
LQEHVKRVTAPYKYP	ACSM5	536	Q6NUN0
PSGLEKLKEIHYPPY	ALDH3B2	351	P48448
QKDYNHLPTGPLDKY	DMAC2L	86	Q99766
GYIYPLQDPKNLILK	RGS9	81	O75916
DLKPYESIPHQYKLD	IPPK	441	Q9H8X2
DPEDPHKGFKYLYLT	ACACB	1851	O00763
YPIKPYHLKGIHRAV	ANKRD36C	26	Q5JPF3
LEGLYAKVNKPYHPL	PARD3B	996	Q8TEW8
PENLLYYHPGEESKI	PSKH2	186	Q96QS6
QLPLPYEQLKHFYRK	MAD2L1BP	86	Q15013
LVSYPGKNKIPLNYH	NCBP1	336	Q09161
KSPDHLPDLYVKIYV	PCLO	5041	Q9Y6V0
KARHPPSYVVYGLKL	PCNX2	926	A6NKB5
AGPKLYPKLYTDIHT	FGFRL1	466	Q8N441
LTTHKEELYPKNPYL	MSTO1	101	Q9BUK6
KLHYYEKQSPVPILH	MPP7	56	Q5T2T1
KLKYHQYIPPDQKGE	MRTFB	291	Q9ULH7
LVIPSPVLVKLYKYH	PI4KA	511	P42356
DSGYLHLLYKRPLDP	NUP214	791	P35658
VLKHKLDELYPQGYP	MSLN	351	Q13421
VFDHYGKIIQKTPYP	PMS2P1	336	A4D2B8
DKPLLVKDHQYGLPI	NOL10	261	Q9BSC4
EKIYYLKLHPDHPET	GARIN1B	171	Q96KD3
ELKGPIDHSYFDKYP	PRKG2	731	Q13237
VDFHAPYKLPYKELL	PUS10	31	Q3MIT2
PGSYKHPKYLELILL	ADAM30	196	Q9UKF2
PVLKVYQDHKQPEYI	DNAH6	76	Q9C0G6
AYIKIYQGEELPHPK	ATL1	331	Q8WXF7
LDPKYAHIQVTYVKP	DOCK11	1826	Q5JSL3
TGPDYIKDYLPKIHQ	C4orf45	21	Q96LM5
HGEQYLELYKPLPRA	HSD17B4	406	P51659
FKKYEVLALLYHEPP	CASQ1	61	P31415
YKPHDLQPGKKYPTV	DPP8	651	Q6V1X1
EIDLEKYKLLPEYPG	DHFR	151	P00374
KVLYRPDGQHDGKLY	CNTN1	941	Q12860
KVLLPKIYPWLYHNG	GLB1L	161	Q6UWU2
LRKYEPHGPLVNSEY	GLB1L	251	Q6UWU2
KAYIKIYQGEDLPHP	ATL3	326	Q6DD88
PHTYIQKLKGYLDPA	FMNL2	76	Q96PY5
LVPEKLTPHLKYYVA	ERAP2	151	Q6P179
EIDLEKYKLLPEYPG	DHFR2	151	Q86XF0
NEHPVFAYLKDKLPY	GPX2	111	P18283
YGKPLSYPLEIHVKV	CDH17	316	Q12864
VVKDKAGPHKEIYPY	COX5A	111	P20674
LHRLQKGPGYTYKEL	SCNN1B	11	P51168
KPKAVIPIYEGDYHP	LRRC43	616	Q8N309
FYYKDHLPRLGKPAE	MIB2	231	Q96AX9
KYFAKHPRLGYLPVQ	UTRN	3141	P46939
YTLNKLEPGGKYHII	SORL1	1991	Q92673
ENPLKYLYPNIDKDH	STAT1	661	P42224
PKPYYDIVKSGIHVK	TEX14	481	Q8IWB6
GPHLYYVDPVNKVLK	PDPK1	481	O15530
VPEPEYLQKLHKYLI	GPAM	746	Q9HCL2
KLNELGYEVLPHPPY	SETMAR	601	Q53H47
NLEKYHLPYPEAIFE	SIRT2	106	Q8IXJ6
YFLYEALHGPPKKIL	ADSS2	236	P30520
LLYPLERGFIYVHKP	SSRP1	351	Q08945
PHRDKKLKYYIPEVV	B3GNT2	281	Q9NY97
NPYKHLPIYSEKIVD	MYH11	126	P35749
LKKSDRYYHGPTPIQ	GTF2H1	376	P32780
KPNYKLDHIIKERYP	PES1	111	O00541
LHKQTKPYELPYRKE	TMEM232	641	C9JQI7
LYPDIPKDKAFGKHY	STAT4	661	Q14765
YHPPNIIGVEKKEGY	PIEZO2	2001	Q9H5I5
GKKADVIPVHYYLIP	TPP2	981	P29144
AKYIYHKHDPALPRL	NUP188	856	Q5SRE5
HPVYYPALEKILELG	PIK3CD	481	O00329
LYPAPLESLDYKGHV	PRAMEF10	411	O60809
LEKPKYEPNPHYHEN	SENP6	776	Q9GZR1
ELYEKLPQGYRLEKP	TEK	1046	Q02763
VAKSPYILKGPVYHE	POGLUT2	121	Q6UW63
PRGKIYEIYLTLHKP	UNC5A	471	Q6ZN44
IPVHPIGYYDAEKLL	nan	486	Q3C1V9
LRKNPDKFHGYEEPY	ZNF26	146	P17031
KPHLYEGDNLYCPKD	TTC7A	326	Q9ULT0
HPDKLKVLLPFIAYY	GTF3C5	276	Q9Y5Q8
RYYPDHIKGLILKGD	TMTC3	731	Q6ZXV5
ELKLPPTDAYYKLRH	EFTUD2	266	Q15029
VPIIPSYLYSIKHEK	SLC18A2	41	Q05940
KGLLKLPFADAYHPE	KLHL35	311	Q6PF15
PKLFLYDAKDLHPGV	IGKV1D-42	66	A0A075B6H8