Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	WAPL DNAH12 KIF15 MYO18A NAV2 RNF213 MYO1B MSH2 HSPA2 SNRNP200 KIF11 RAD50	1.56e-05	614	88	12	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal protein binding	EPS8L2 NRAP KIF15 HOOK1 SYNE2 MYO18A DNM1L TOGARAM1 TLN2 MYO1B MICAL3 CTNNA2 DCTN1 HSPA2 CNN1 KIF11	2.17e-05	1099	88	16	GO:0008092
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RALB DNAH12 KIF15 RAB8B MYO18A NAV2 RASD1 RNF213 DNM1L MSH2 HSPA2 SNRNP200 RAD50	3.35e-05	775	88	13	GO:0017111
GeneOntologyMolecularFunction	actin binding	EPS8L2 NRAP HOOK1 SYNE2 MYO18A TLN2 MYO1B MICAL3 CTNNA2 CNN1	4.87e-05	479	88	10	GO:0003779
GeneOntologyMolecularFunction	actin filament binding	EPS8L2 NRAP MYO18A TLN2 MYO1B CTNNA2 CNN1	6.50e-05	227	88	7	GO:0051015
GeneOntologyMolecularFunction	pyrophosphatase activity	RALB DNAH12 KIF15 RAB8B MYO18A NAV2 RASD1 RNF213 DNM1L MSH2 HSPA2 SNRNP200 RAD50	7.54e-05	839	88	13	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RALB DNAH12 KIF15 RAB8B MYO18A NAV2 RASD1 RNF213 DNM1L MSH2 HSPA2 SNRNP200 RAD50	7.63e-05	840	88	13	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RALB DNAH12 KIF15 RAB8B MYO18A NAV2 RASD1 RNF213 DNM1L MSH2 HSPA2 SNRNP200 RAD50	7.63e-05	840	88	13	GO:0016818
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH12 KIF15 MYO18A NAV2 RNF213 MSH2 HSPA2 SNRNP200 RAD50	1.41e-04	441	88	9	GO:0016887
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH12 KIF15 MYO18A MYO1B KIF11	1.75e-04	118	88	5	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	WAPL MYO18A NAV2 MSH2 RAD50	2.47e-04	127	88	5	GO:0008094
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	WAPL MYO18A NAV2 MSH2 NIPBL RAD50	1.06e-03	262	88	6	GO:0140097
GeneOntologyBiologicalProcess	mitotic cell cycle process	CUL5 SLFN12L EXOC5 WAPL KIF15 ETAA1 BARD1 MSH2 CDC27 DCTN1 CIT HSPA2 NIPBL KIF11 RAD50	3.48e-06	854	89	15	GO:1903047
GeneOntologyBiologicalProcess	mitotic cell cycle	CUL5 SLFN12L EXOC5 WAPL KIF15 MEIOC ETAA1 BARD1 MSH2 CDC27 DCTN1 CIT HSPA2 NIPBL KIF11 RAD50	6.20e-06	1014	89	16	GO:0000278
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	6.40e-06	9	89	3	GO:0160063
GeneOntologyBiologicalProcess	cell cycle process	CUL5 PDS5B SLFN12L EXOC5 WAPL KIF15 MEIOC ETAA1 BARD1 MSH2 CDC27 DCTN1 CIT HSPA2 NIPBL KIF11 DYRK3 RAD50	3.65e-05	1441	89	18	GO:0022402
GeneOntologyBiologicalProcess	chromosome organization	PDS5B WAPL KIF15 MEIOC NAV2 MSH2 CDC27 CIT HSPA2 NIPBL KIF11 RAD50	3.80e-05	686	89	12	GO:0051276
GeneOntologyBiologicalProcess	cell cycle G2/M phase transition	ETAA1 BARD1 CIT HSPA2 DYRK3 RAD50	9.78e-05	171	89	6	GO:0044839
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO2 NOMO3 NOMO1	5.95e-06	9	88	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO2 NOMO3 NOMO1	2.54e-05	14	88	3	GO:0072379
GeneOntologyCellularComponent	BRCA1-C complex	BARD1 RAD50	2.60e-04	6	88	2	GO:0070533
GeneOntologyCellularComponent	intercellular bridge	RBM44 WAPL MICAL3 DCTN1	6.70e-04	94	88	4	GO:0045171
GeneOntologyCellularComponent	spindle	WAPL KIF15 MICAL3 CDC27 DCTN1 HSPA2 KIF11 INVS	8.32e-04	471	88	8	GO:0005819
GeneOntologyCellularComponent	postsynaptic endosome membrane	SNX1 STX12	9.40e-04	11	88	2	GO:0098895
GeneOntologyCellularComponent	supramolecular fiber	DNAH12 NRAP KIF15 HOOK1 SYNE2 MYO18A DNM1L TOGARAM1 MYO1B DCTN1 RYR3 KIF11 INVS	1.27e-03	1179	88	13	GO:0099512
GeneOntologyCellularComponent	fascia adherens	NRAP TLN2	1.33e-03	13	88	2	GO:0005916
GeneOntologyCellularComponent	supramolecular polymer	DNAH12 NRAP KIF15 HOOK1 SYNE2 MYO18A DNM1L TOGARAM1 MYO1B DCTN1 RYR3 KIF11 INVS	1.35e-03	1187	88	13	GO:0099081
Domain	DUF2012	NOMO2 NOMO3 NOMO1	3.76e-07	4	86	3	PF09430
Domain	DUF2012	NOMO2 NOMO3 NOMO1	3.76e-07	4	86	3	IPR019008
Domain	Carb-bd-like_fold	NOMO2 NOMO3 NOMO1	5.19e-06	8	86	3	IPR013784
Domain	CarboxyPept_regulatory_dom	NOMO2 NOMO3 NOMO1	2.61e-05	13	86	3	IPR014766
Domain	-	NOMO2 NOMO3 NOMO1	2.61e-05	13	86	3	2.60.40.1120
Domain	P-loop_NTPase	RALB DNAH12 KIF15 RAB8B MYO18A NAV2 RASD1 RNF213 DNM1L MYO1B MSH2 SNRNP200 KIF11 RAD50	3.07e-05	848	86	14	IPR027417
Domain	CarboxyPept-like_regulatory	NOMO2 NOMO3 NOMO1	6.12e-05	17	86	3	IPR008969
Domain	CH	SYNE2 NAV2 MICAL3 CNN1	2.29e-04	65	86	4	SM00033
Domain	CH	SYNE2 NAV2 MICAL3 CNN1	3.05e-04	70	86	4	PF00307
Domain	-	SYNE2 NAV2 MICAL3 CNN1	3.22e-04	71	86	4	1.10.418.10
Domain	CH	SYNE2 NAV2 MICAL3 CNN1	3.58e-04	73	86	4	PS50021
Domain	CH-domain	SYNE2 NAV2 MICAL3 CNN1	3.97e-04	75	86	4	IPR001715
Domain	Vinculin/catenin	TLN2 CTNNA2	4.34e-04	7	86	2	IPR006077
Domain	-	RALB DNAH12 RAB8B MYO18A NAV2 RASD1 RNF213 DNM1L MSH2 SNRNP200 RAD50	6.13e-04	746	86	11	3.40.50.300
Domain	Glyco_transf_8	GXYLT1 UGGT2	9.21e-04	10	86	2	PF01501
Domain	Glyco_trans_8	GXYLT1 UGGT2	9.21e-04	10	86	2	IPR002495
Domain	ARM-type_fold	PDS5B WAPL PIK3CD RRP12 TOGARAM1 NIPBL RYR3	9.61e-04	339	86	7	IPR016024
Domain	HMG_box	SOX6 KMT2D HMG20B	1.87e-03	53	86	3	PF00505
Domain	HMG	SOX6 KMT2D HMG20B	1.97e-03	54	86	3	SM00398
Domain	-	SOX6 KMT2D HMG20B	2.08e-03	55	86	3	1.10.30.10
Domain	Post-SET_dom	KMT2D NSD1	2.41e-03	16	86	2	IPR003616
Domain	PostSET	KMT2D NSD1	2.41e-03	16	86	2	SM00508
Domain	POST_SET	KMT2D NSD1	2.41e-03	16	86	2	PS50868
Domain	HMG_box_dom	SOX6 KMT2D HMG20B	3.35e-03	65	86	3	IPR009071
Domain	HEAT_REPEAT	PDS5B TOGARAM1 NIPBL	4.13e-03	70	86	3	PS50077
Domain	IQ	MYO18A MYO1B INVS	4.30e-03	71	86	3	PF00612
Domain	AAA+_ATPase	DNAH12 NAV2 RNF213 SNRNP200	4.41e-03	144	86	4	IPR003593
Domain	AAA	DNAH12 NAV2 RNF213 SNRNP200	4.41e-03	144	86	4	SM00382
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B WAPL NIPBL	9.98e-06	10	63	3	M27178
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B WAPL NIPBL	9.98e-06	10	63	3	MM14892
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	PDS5B WAPL NIPBL	2.36e-05	13	63	3	MM15363
Pathway	REACTOME_MITOTIC_TELOPHASE_CYTOKINESIS	PDS5B WAPL NIPBL	2.36e-05	13	63	3	M27661
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	EXOC5 EPS8L2 WAPL DNM1L TLN2 MSH2 CDC27 DCTN1 INTS8 NIPBL SNRNP200 KIF11 RAD50	3.11e-09	582	89	13	20467437
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	HOOK1 MYO18A RNF213 DNM1L PYGL TLN2 MSH2 KIF11 RAD50	3.46e-09	208	89	9	33230847
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO2 NOMO3 NOMO1	1.62e-08	3	89	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO2 NOMO3 NOMO1	1.62e-08	3	89	3	25576386
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B PSAT1 WAPL RRP12 LARS1 COPS4 DNM1L TLN2 MYO1B MSH2 HADHB DCTN1 NIPBL SNRNP200 KIF11 STX12 NOMO1 RAD50	1.82e-08	1425	89	18	30948266
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO2 NOMO3 NOMO1	6.47e-08	4	89	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO2 NOMO3 NOMO1	6.47e-08	4	89	3	9267806
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	WAPL MSH2 CDC27 HSPA2 SNRNP200 RAD50	1.01e-07	87	89	6	24169447
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PSAT1 WAPL SH3D19 RRP12 LARS1 COPS4 DNM1L MYO1B DCTN1 NIPBL SNRNP200 SNX1 KIF11 RAD50	1.09e-07	934	89	14	33916271
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SOX6 WAPL NOMO2 SH3D19 LARS1 COPS4 TLN2 ARMCX4 DCTN1 INTS8 CIT HSPA2 NIPBL SNRNP200 SNX1 RYR3	1.53e-07	1285	89	16	35914814
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF15 HOOK1 SH3D19 SYNE2 NSD1 DNM1L TLN2 CTNNA2 ARMCX4 DCTN1 CIT NIPBL KIF11 RAD50	1.58e-07	963	89	14	28671696
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	WAPL LARS1 RNF213 DNM1L MSH2 NIPBL SNRNP200 KIF11 RAD50	1.92e-07	332	89	9	32786267
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PDS5B EXOC5 WAPL HOOK1 NOMO2 MYO1B HADHB CDC27 SNRNP200 KIF11 RAD50	2.01e-07	560	89	11	35241646
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	PSAT1 HOOK1 RRP12 LARS1 MYO18A COPS4 DNM1L PYGL MYO1B MICAL3 DCTN1 HSPA2 SNRNP200 KIF11 RAD50	2.16e-07	1149	89	15	35446349
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RALB EXOC5 HOOK1 UBE3D LARS1 COPS4 PYGL UGGT2 MSH2 CDC27 DCTN1 BBS12 SNRNP200 INVS NOMO1 RAD50	2.22e-07	1321	89	16	27173435
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	EXOC5 RRP12 SYNE2 LARS1 PYGL TLN2 MYO1B MSH2 CTNNA2 RAD50	6.13e-07	498	89	10	36634849
Pubmed	A protein interaction landscape of breast cancer.	MYO18A COPS4 NAV2 BARD1 MYO1B MSH2 CTNNA2 HADHB CDC27 HSPA2 STX12	6.84e-07	634	89	11	34591612
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CUL5 PSAT1 EXOC5 RRP12 SYNE2 LARS1 RNF213 MYO1B MICAL3 MSH2 CTNNA2 HADHB HSPA2 SNRNP200 STX12 RAD50	6.98e-07	1440	89	16	30833792
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDS5B WAPL HOOK1 RRP12 LARS1 UGGT2 MSH2 HADHB INTS8 HSPA2 NOMO3 KIF11 STX12	8.18e-07	942	89	13	31073040
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO2 NOMO3 NOMO1	8.99e-07	8	89	3	15257293
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PDS5B RRP12 SYNE2 NSD1 PYGL MYO1B MSH2 HSPA2 NIPBL SNRNP200 RAD50	9.12e-07	653	89	11	22586326
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	LRRC31 RRP12 MYO18A MYO1B MSH2 CIT SNRNP200	9.25e-07	202	89	7	33005030
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	EPS8L2 NOMO2 SYNE2 LARS1 COPS4 DNM1L GXYLT1 UGGT2 MYO1B CTNNA2 HADHB CDC27 NIPBL SNX1 KIF11	9.92e-07	1297	89	15	33545068
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	PPIG RRP12 LARS1 COPS4 DNM1L PYGL MYO1B HADHB DCTN1 HSPA2 SNRNP200	1.09e-06	665	89	11	30457570
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO2 NOMO3 NOMO1	1.35e-06	9	89	3	36261522
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	RRP12 RNF213 MYO1B MSH2 HADHB SNRNP200	1.99e-06	144	89	6	35681168
Pubmed	SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.	CUL5 PDS5B RRP12 LARS1 COPS4 MSH2	2.52e-06	150	89	6	30154076
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO2 NOMO3 NOMO1	2.63e-06	11	89	3	32820719
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B RALB HOOK1 RAB8B SYNE2 MYO18A NAV2 UGGT2 MYO1B HADHB CDC27 DCTN1 HSPA2 NIPBL KIF11	3.65e-06	1442	89	15	35575683
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	NOMO2 COPS4 LAMB2 UGGT2 HADHB SNRNP200 NOMO3 KIF11 NOMO1 RAD50	3.92e-06	613	89	10	22268729
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PDS5B KMT2D LARS1 COPS4 PYGL MSH2 HADHB CIT NIPBL SNRNP200 KIF11 HMG20B RAD50	4.62e-06	1103	89	13	34189442
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDS5B PPIG KMT2D WAPL RRP12 MYO18A TLN2 MICAL3 NIPBL SNRNP200 RAD50	4.67e-06	774	89	11	15302935
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	CUL5 COPS4 RNF213 PYGL MSH2 HADHB DCTN1 SNRNP200 KIF11	5.17e-06	495	89	9	28581483
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PDS5B WAPL DNAH12 KIF15 RRP12 COPS4 NAV2 MICAL3 RYR3	5.34e-06	497	89	9	36774506
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	LARS1 DNM1L MSH2 HADHB DCTN1 HSPA2 SNRNP200 KIF11 NOMO1 RAD50	5.57e-06	638	89	10	33239621
Pubmed	Expression of SoxE and SoxD genes in human gliomas.	SOX6 HMG20B	6.48e-06	2	89	2	17961134
Pubmed	Balanced activity of three mitotic motors is required for bipolar spindle assembly and chromosome segregation.	KIF15 KIF11	6.48e-06	2	89	2	25127142
Pubmed	The PI3K p110δ regulates expression of CD38 on regulatory T cells.	PIK3CD CD38	6.48e-06	2	89	2	21390257
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PDS5B WAPL SH3D19 RRP12 COPS4 TLN2 MICAL3 POC5 HADHB CDC27 DCTN1 NIPBL SNRNP200	7.58e-06	1155	89	13	20360068
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PDS5B WAPL RRP12 LARS1 PYGL MYO1B MSH2 HADHB CDC27 DCTN1 NIPBL SNRNP200 KIF11 RAD50	8.49e-06	1353	89	14	29467282
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	TSHZ3 KMT2D SYNE2 PYGL HADHB HSPA2 SNX1 KIF11	8.63e-06	398	89	8	35016035
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SYNE2 MYO18A RNF213 CTNNA2 HSPA2 KIF11	8.95e-06	187	89	6	26460568
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	PSAT1 MYO18A MYO1B HADHB NOMO3 NOMO1	1.01e-05	191	89	6	33762435
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PDS5B RRP12 SYNE2 LARS1 LAMB2 MYO1B MSH2 HADHB CIT NIPBL SNRNP200 RAD50	1.18e-05	1024	89	12	24711643
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PSAT1 KMT2D KIF15 RRP12 SYNE2 RNF213 MYO1B MICAL3 MSH2 POC5 HADHB HSPA2	1.49e-05	1049	89	12	27880917
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	PSAT1 SLC25A2 CD38 COPS4 RNF213 UGGT2 CTNNA2 INTS8 HSPA2 SNX1 NOTCH3 STX12	1.67e-05	1061	89	12	33845483
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	RRP12 CDC27 CIT NIPBL SNRNP200 KIF11	1.73e-05	210	89	6	16565220
Pubmed	Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150.	DCTN1 KIF11	1.94e-05	3	89	2	9235942
Pubmed	The germline variants in DNA repair genes in pediatric medulloblastoma: a challenge for current therapeutic strategies.	MSH2 RAD50	1.94e-05	3	89	2	28376765
Pubmed	Dual Specificity Kinase DYRK3 Promotes Aggressiveness of Glioblastoma by Altering Mitochondrial Morphology and Function.	DNM1L DYRK3	1.94e-05	3	89	2	33804169
Pubmed	PtdIns(4)P regulates retromer-motor interaction to facilitate dynein-cargo dissociation at the trans-Golgi network.	DCTN1 SNX1	1.94e-05	3	89	2	23524952
Pubmed	Destabilization of mRNAs enhances competence to initiate meiosis in mouse spermatogenic cells.	MEIOC HSPA2	1.94e-05	3	89	2	38884383
Pubmed	Decreasing Wapl dosage partially corrects embryonic growth and brain transcriptome phenotypes in Nipbl+/- embryos.	WAPL NIPBL	1.94e-05	3	89	2	36449618
Pubmed	Absolute quantification of cohesin, CTCF and their regulators in human cells.	WAPL NIPBL	1.94e-05	3	89	2	31204999
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	WAPL SYNE2 LARS1 MYO18A COPS4 HADHB DCTN1 SNRNP200 SNX1 RAD50	2.35e-05	754	89	10	35906200
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	EPS8L2 MYO18A RNF213 DNM1L PYGL MYO1B DCTN1 SNRNP200 RAD50	2.41e-05	601	89	9	33658012
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	CUL5 PDS5B KMT2D WAPL RNF213 MSH2 INTS8	2.83e-05	341	89	7	32971831
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RNF213 PYGL MYO1B DCTN1 HSPA2 SNRNP200 KIF11	3.00e-05	344	89	7	36282215
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	PDS5B PPIG WAPL MEIOC RRP12 LARS1 DNM1L PYGL MSH2 HADHB CDC27 NIPBL SNRNP200	3.03e-05	1318	89	13	30463901
Pubmed	MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.	KMT2D PIK3CD	3.87e-05	4	89	2	36701842
Pubmed	Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.	PDS5B WAPL	3.87e-05	4	89	2	29217591
Pubmed	Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.	WAPL RNF213	3.87e-05	4	89	2	18187866
Pubmed	Inhibition of Drp1 SUMOylation by ALR protects the liver from ischemia-reperfusion injury.	KMT2D DNM1L	3.87e-05	4	89	2	33110216
Pubmed	The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.	PIK3CD CD38	3.87e-05	4	89	2	21390242
Pubmed	Epidermal development requires ninein for spindle orientation and cortical microtubule organization.	CTNNA2 DCTN1 NOTCH3	4.04e-05	26	89	3	30923192
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL5 COPS4 BARD1 PYGL UGGT2 MSH2 N4BP3 CDC27 SNRNP200 KIF11 RAD50	5.19e-05	1005	89	11	19615732
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	LARS1 DNM1L TLN2 MSH2 DCTN1 CIT HSPA2 NIPBL SNRNP200 RAD50	6.24e-05	847	89	10	35235311
Pubmed	The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.	EPS8L2 SYNE2 SNX1	6.26e-05	30	89	3	30480076
Pubmed	The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport.	DCTN1 SNX1	6.44e-05	5	89	2	19935774
Pubmed	The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.	WAPL CDC27 NIPBL SNRNP200	6.61e-05	84	89	4	26299517
Pubmed	Hepatic lipase maturation: a partial proteome of interacting factors.	NOMO2 NOMO3 NOMO1	6.91e-05	31	89	3	19136429
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	MSH2 HSPA2 SNRNP200 RAD50	6.92e-05	85	89	4	16051665
Pubmed	Human transcription factor protein interaction networks.	SOX6 TSHZ3 KMT2D RRP12 SYNE2 LARS1 MYO18A MYO1B HADHB CIT NIPBL HMG20B RAD50	6.93e-05	1429	89	13	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CUL5 LARS1 MYO18A DNM1L TLN2 MICAL3 CTNNA2 HADHB DCTN1 CIT PCDH1 HSPA2 SNRNP200	7.03e-05	1431	89	13	37142655
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	PDS5B WAPL MYO1B MSH2 NIPBL SNRNP200	7.31e-05	272	89	6	31010829
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	RALB EXOC5 NOTCH3 RYR3 KIF11	7.41e-05	168	89	5	30631154
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PDS5B LARS1 MSH2 HADHB DCTN1 NIPBL SNRNP200 KIF11 RAD50	8.15e-05	704	89	9	29955894
Pubmed	Genetic variation in genes interacting with BRCA1/2 and risk of breast cancer in the Cypriot population.	BARD1 MSH2 RAD50	8.36e-05	33	89	3	19714462
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	NOMO2 NOMO3 NOMO1	8.36e-05	33	89	3	30783098
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2D WAPL SH3D19 NSD1 DCTN1 SNRNP200 SNX1 RAD50	8.44e-05	549	89	8	38280479
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	NOMO2 LARS1 PYGL MYO1B MSH2 HADHB CDC27 DCTN1 HSPA2 SNRNP200 NOMO3 NOMO1	8.60e-05	1257	89	12	37317656
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	PSAT1 NOMO2 MYO18A COPS4 MYO1B DCTN1 NOMO3 NOMO1	8.76e-05	552	89	8	36293380
Pubmed	Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.	BARD1 RAD50	9.65e-05	6	89	2	18171670
Pubmed	TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly.	DCTN1 KIF11	9.65e-05	6	89	2	14718566
Pubmed	Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1.	BARD1 MSH2	9.65e-05	6	89	2	11498787
Pubmed	The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.	BARD1 RAD50	9.65e-05	6	89	2	29709199
Pubmed	CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.	BARD1 RAD50	9.65e-05	6	89	2	30657944
Pubmed	Symbionts exploit complex signaling to educate the immune system.	PIK3CD TLR6	9.65e-05	6	89	2	31811024
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	LARS1 PYGL MSH2 KIF11 RAD50	9.99e-05	179	89	5	36261009
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TSHZ3 KMT2D KIF15 DCTN1 KIF11 HMG20B RAD50	1.02e-04	418	89	7	34709266
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EPS8L2 SH3D19 NAV2 MYO1B CTNNA2 PCDH1 SNX1 NOTCH3	1.03e-04	565	89	8	25468996
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EXOC5 NOMO2 RRP12 SYNE2 MYO18A COPS4 UGGT2 HADHB DCTN1 HSPA2 SNRNP200 SNX1 NOMO1	1.03e-04	1487	89	13	33957083
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CUL5 PDS5B PPIG HOOK1 RRP12 LARS1 COPS4 MYO1B MSH2 DCTN1 SNRNP200 RAD50	1.05e-04	1284	89	12	17353931
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	CUL5 NOMO2 RRP12 LARS1 PYGL MSH2 DCTN1 RAD50	1.11e-04	571	89	8	37167062
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PPIG KMT2D RRP12 NSD1 BARD1 MSH2 HADHB CDC27 NIPBL SNRNP200 HMG20B RAD50	1.13e-04	1294	89	12	30804502
Pubmed	Loss of Notch2 and Notch3 in vascular smooth muscle causes patent ductus arteriosus.	CNN1 NOTCH3	1.35e-04	7	89	2	26453897
Pubmed	Redistribution of BRCA1 among four different protein complexes following replication blockage.	BARD1 RAD50	1.35e-04	7	89	2	11504724
Pubmed	Epidemiology of the antibiotic resistance of Helicobacter pylori in Canada.	PDS5B WAPL	1.35e-04	7	89	2	11111111
Pubmed	A novel hook-related protein family and the characterization of hook-related protein 1.	HOOK1 SNX1	1.35e-04	7	89	2	15882442
Pubmed	Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development.	SLFN12L MEIOC HSPA2	1.38e-04	39	89	3	38226173
Interaction	SNW1 interactions	EXOC5 EPS8L2 WAPL HOOK1 DNM1L MSH2 CDC27 DCTN1 CIT HSPA2 NIPBL SNRNP200 NOTCH3 KIF11 RAD50	4.79e-07	747	85	15	int:SNW1
Interaction	KCNA3 interactions	HOOK1 SH3D19 LARS1 MYO18A RNF213 DNM1L PYGL TLN2 MYO1B MICAL3 MSH2 CDC27 SNRNP200 SHC3 KIF11 RAD50	6.19e-07	871	85	16	int:KCNA3
Interaction	H3C1 interactions	PDS5B KMT2D WAPL RRP12 MYO18A NSD1 NAV2 BARD1 UGGT2 MSH2 CDC27 NIPBL ANKRD18B KIF11 RAD50	4.87e-06	901	85	15	int:H3C1
Interaction	CDC5L interactions	EXOC5 EPS8L2 HOOK1 DNM1L TLN2 MSH2 CDC27 INTS8 CIT HSPA2 NIPBL SNRNP200 KIF11 RAD50	1.27e-05	855	85	14	int:CDC5L
Interaction	NAA40 interactions	PSAT1 WAPL SH3D19 RRP12 LARS1 COPS4 DNM1L MYO1B DCTN1 CIT NIPBL SNRNP200 SNX1 KIF11 RAD50	1.30e-05	978	85	15	int:NAA40
Interaction	DNAJC10 interactions	CUL5 WAPL LAMB2 UGGT2 HADHB CIT NOTCH3 NOMO1	1.41e-05	260	85	8	int:DNAJC10
Interaction	LRRC31 interactions	LRRC31 RRP12 MYO18A MYO1B MSH2 CIT SNRNP200	2.57e-05	205	85	7	int:LRRC31
Interaction	BIRC3 interactions	PDS5B PSAT1 WAPL RRP12 LARS1 COPS4 DNM1L TLN2 MYO1B MSH2 HADHB DCTN1 SNRNP200 KIF11 STX12 NOMO1 RAD50	3.52e-05	1334	85	17	int:BIRC3
Interaction	HERC2 interactions	PPIG KMT2D KIF15 HOOK1 LRRC31 SYNE2 ETAA1 NSD1 BARD1 KIF11	5.02e-05	503	85	10	int:HERC2
Interaction	C9orf78 interactions	PDS5B EXOC5 WAPL HOOK1 NOMO2 MYO1B HADHB CDC27 SNRNP200 KIF11 RAD50	5.79e-05	620	85	11	int:C9orf78
Interaction	SIRT7 interactions	PDS5B RRP12 SYNE2 COPS4 NSD1 PYGL MYO1B MSH2 HSPA2 NIPBL SNRNP200 RAD50	6.52e-05	744	85	12	int:SIRT7
Interaction	H3-3A interactions	PDS5B TSHZ3 KMT2D WAPL NSD1 BARD1 MSH2 HADHB CDC27 NIPBL KIF11 RAD50	6.95e-05	749	85	12	int:H3-3A
Interaction	STAG1 interactions	PDS5B WAPL CIT NIPBL SNRNP200	7.85e-05	104	85	5	int:STAG1
Interaction	FBXO22 interactions	PDS5B WAPL DNAH12 KIF15 RRP12 COPS4 NAV2 MICAL3 CIT RYR3	9.06e-05	540	85	10	int:FBXO22
Interaction	EED interactions	PDS5B PSAT1 EPS8L2 RRP12 LARS1 MYO18A NSD1 DNM1L MYO1B MSH2 DCTN1 INTS8 CIT NIPBL SNRNP200 KIF11 RAD50	9.51e-05	1445	85	17	int:EED
Interaction	CIT interactions	PDS5B DNAH12 HOOK1 LRRC31 RRP12 SYNE2 MYO18A RNF213 MYO1B HADHB DCTN1 CIT HSPA2 NIPBL SNRNP200 KIF11 DYRK3	9.92e-05	1450	85	17	int:CIT
Interaction	CDH8 interactions	CTNNA2 HADHB PCDH1	1.05e-04	22	85	3	int:CDH8
Interaction	CLTA interactions	PSAT1 KIF15 SH3D19 MYO18A CIT HSPA2 STX12 INVS	1.17e-04	351	85	8	int:CLTA
Interaction	TOP2B interactions	CUL5 LRRC31 BARD1 MSH2 CIT SNRNP200 RAD50	1.32e-04	266	85	7	int:TOP2B
Interaction	SNRNP200 interactions	CUL5 WAPL LRRC31 BARD1 MSH2 HADHB CIT NIPBL SNRNP200	1.38e-04	460	85	9	int:SNRNP200
Interaction	LMBR1L interactions	PDS5B WAPL HOOK1 RRP12 LARS1 UGGT2 MSH2 HADHB INTS8 HSPA2 NOMO3 KIF11 STX12	1.59e-04	946	85	13	int:LMBR1L
Interaction	ERCC8 interactions	CUL5 COPS4 DNM1L HSPA2 SNRNP200	1.80e-04	124	85	5	int:ERCC8
Interaction	SUMO2 interactions	SOX6 WAPL LARS1 RNF213 DNM1L MSH2 NIPBL SNRNP200 KIF11 RAD50	1.89e-04	591	85	10	int:SUMO2
Cytoband	19p13.2-p13.1	CNN1 NOTCH3	1.11e-05	3	89	2	19p13.2-p13.1
Cytoband	10q24.1	RRP12 KIF11	8.37e-04	22	89	2	10q24.1
Cytoband	5q35.3	OR2V1 OR2V2 N4BP3	8.57e-04	95	89	3	5q35.3
Cytoband	Ensembl 112 genes in cytogenetic band chr5q35	NSD1 OR2V1 OR2V2 N4BP3	1.16e-03	235	89	4	chr5q35
Cytoband	Ensembl 112 genes in cytogenetic band chr15q22	RAB8B TLN2 SNX1	2.20e-03	132	89	3	chr15q22
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP	PSAT1 KIF15 HOOK1 CD38 BARD1 RNF213 KIF11	2.84e-06	183	88	7	M2993
Coexpression	RPS14_DN.V1_DN	PSAT1 KIF15 LRRC20 TLN2 MSH2 DYRK3	3.94e-05	186	88	6	M2812
Coexpression	TBK1.DF_DN	CUL5 PPIG EXOC5 HOOK1 COPS4 MSH2 CDC27	5.11e-05	286	88	7	M2864
Coexpression	BROWNE_HCMV_INFECTION_14HR_DN	PRRX1 PIK3CD MYO1B N4BP3 CIT NIPBL RAD50	5.58e-05	290	88	7	M13251
Coexpression	GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN	PDS5B RAB8B DNM1L CIT KIF11 RAD50	5.90e-05	200	88	6	M6252
Coexpression	GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN	SLFN12L LARS1 POC5 ARMCX4 INTS8 HSPA2	5.90e-05	200	88	6	M4015
Coexpression	HALLMARK_G2M_CHECKPOINT	CUL5 PDS5B KIF15 BARD1 CDC27 KIF11	5.90e-05	200	88	6	M5901
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	PPIG EXOC5 PRRX1 KIF15 SH3D19 CDC27 SNX1 KIF11 HMG20B	6.23e-05	519	88	9	M3395
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_21_PRECICTIVE_ICB_RESISTANCE	NOMO2 RRP12 ETAA1 GXYLT1 NOMO3 NOMO1	6.95e-05	206	88	6	MM17087
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	PDS5B PPIG KIF15 SYNE2 ETAA1 DNM1L MSH2 NIPBL KIF11 RAD50	7.03e-05	656	88	10	M18979
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_INTERM_CHONDROCYTE	SOX6 PSAT1 PRRX1 PYGL	8.20e-05	68	88	4	M45669
Coexpression	MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN	PPIG EXOC5 PRRX1 KIF15 SH3D19 CDC27 SNX1 KIF11 HMG20B	8.80e-05	543	88	9	MM997
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	CUL5 SOX6 PPIG EXOC5 WAPL KIF15 HOOK1 SYNE2 ETAA1 NSD1 OR2V2 CDC27 CIT NIPBL CNN1 KIF11 DYRK3 RAD50	1.61e-06	1257	84	18	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	CUL5 SOX6 PPIG EXOC5 WAPL KIF15 HOOK1 SYNE2 ETAA1 NSD1 OR2V2 CDC27 CIT NIPBL SHC3 CNN1 KIF11 DYRK3 RAD50	3.18e-06	1459	84	19	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	EXOC5 WAPL KIF15 HOOK1 ETAA1 MICAL3 BBS12 CIT NIPBL KIF11	4.69e-05	532	84	10	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF15 BARD1 GXYLT1 PYGL TOGARAM1 MICAL3 KIF11	6.79e-08	179	88	7	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	LPS-antiTNF-Unknown-Endothelial-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRAP KIF15 BARD1 CIT RYR3 KIF11	2.53e-07	132	88	6	02491930097b75aaeedab9e8200711b0dc610944
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MEIOC SH3D19 BARD1 TLN2 BBS12 RYR3	9.72e-07	166	88	6	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MEIOC SH3D19 BARD1 TLN2 BBS12 RYR3	9.72e-07	166	88	6	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PRRX1 KIF15 BARD1 CNN1 NOTCH3 KIF11	1.37e-06	176	88	6	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	SLFN12L KMT2D NOMO2 RNF213 STX12 INVS	1.83e-06	185	88	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RBM44 KMT2D BARD1 DNM1L UGGT2 KIF11	2.13e-06	190	88	6	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KIF15 NAV2 BARD1 CIT CNN1 KIF11	2.13e-06	190	88	6	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RBM44 KMT2D BARD1 DNM1L UGGT2 KIF11	2.26e-06	192	88	6	c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	SOX6 PSAT1 KIF15 BARD1 LAMB2 NOTCH3	2.63e-06	197	88	6	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	distal-mesenchymal-Vascular_Smooth_Muscle-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 PRRX1 MYO1B HSPA2 CNN1 NOTCH3	2.63e-06	197	88	6	da653dc7d216e202f390e5ab0245f243e3ed213b
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	SOX6 PSAT1 KIF15 BARD1 LAMB2 NOTCH3	2.63e-06	197	88	6	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-IN_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SOX6 PSAT1 PRRX1 CD38 LAMB2 HADHB	2.70e-06	198	88	6	3811d9e3e54bbe8b208c591697e43b55ab5bbf0e
ToppCell	distal-2-mesenchymal-Vascular_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 PRRX1 MYO1B HSPA2 CNN1 NOTCH3	2.70e-06	198	88	6	ce05ede69c167b2294630709bb0c223483a6ef75
ToppCell	medial-mesenchymal-Vascular_Smooth_Muscle\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 PRRX1 MYO1B HSPA2 CNN1 NOTCH3	2.78e-06	199	88	6	74fe1737a0d63ef0bc49312f1b5823b5c39590dd
ToppCell	medial-2-mesenchymal-Vascular_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 PRRX1 MYO1B HSPA2 CNN1 NOTCH3	2.78e-06	199	88	6	8ce0bcc53b3a955285d614459e45210104a6ed02
ToppCell	medial-mesenchymal-Vascular_Smooth_Muscle-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 PRRX1 MYO1B HSPA2 CNN1 NOTCH3	2.78e-06	199	88	6	263603264ff40ea8ef569cb43f8b84b5938438ab
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	PPIG SYNE2 CDC27 NIPBL ANKRD18B RAD50	2.78e-06	199	88	6	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Transverse-(2)_B_cell-(24)_B_cell_cycling\|Transverse / shred on region, Cell_type, and subtype	PDS5B KIF15 BARD1 TLN2 CIT KIF11	2.86e-06	200	88	6	e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCell	Transverse-B_cell-B_cell_cycling\|Transverse / Region, Cell class and subclass	PDS5B KIF15 BARD1 TLN2 CIT KIF11	2.86e-06	200	88	6	0e270f8019d9f22068ca426d661937262a5cd331
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF15 LRRC20 BARD1 MSH2 CIT KIF11	2.86e-06	200	88	6	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KIF15 CD38 BARD1 MSH2 CIT KIF11	2.86e-06	200	88	6	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	SOX6 LRRC31 EN2 DYRK3 SLC16A10	1.33e-05	153	88	5	654265f3c14344071b2af7ca05cbdbb17ce2c5d3
ToppCell	Enthrocyte\|World / shred on cell class and cell subclass (v4)	SOX6 LRRC31 EN2 DYRK3 SLC16A10	1.33e-05	153	88	5	105b91f5277d145f7717307d7eb9b7d8e8e23576
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RBM44 KMT2D KIF15 CIT RYR3	1.86e-05	164	88	5	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RBM44 KMT2D KIF15 CIT RYR3	1.86e-05	164	88	5	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RBM44 KIF15 BARD1 CIT KIF11	1.91e-05	165	88	5	953c8242a81a39ade63ac8e5b34fe58575771746
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PSAT1 KIF15 PIK3CD CIT KIF11	2.09e-05	168	88	5	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SOX6 PSAT1 EPS8L2 UGGT2 TLR6	2.09e-05	168	88	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	normal_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	SYNE2 MYO1B PCDH1 HSPA2 NOTCH3	2.21e-05	170	88	5	d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8L2 SYNE2 MYO1B CIT SHC3	2.21e-05	170	88	5	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 RASD1 INTS8 CNN1 NOTCH3	2.27e-05	171	88	5	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX6 RASD1 INTS8 CNN1 NOTCH3	2.27e-05	171	88	5	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RBM44 KIF15 PYGL KIF11 SLC16A10	2.27e-05	171	88	5	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PSAT1 ETAA1 CIT NOTCH3 KIF11	2.34e-05	172	88	5	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	KIF15 PIK3CD LRRC20 CIT KIF11	2.54e-05	175	88	5	74800a10f5ff25d5414fbccb0668f92ff077d1cc
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SOX6 KIF15 LRRC20 BARD1 KIF11	2.54e-05	175	88	5	86dfce849b2ec023a72f7e887fa681b117155e51
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PIK3CD RAB8B RRP12 PYGL SNX1	2.61e-05	176	88	5	270d7908dbd84028958d257f94941dc685e20255
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSAT1 KIF15 LRRC20 CIT KIF11	2.90e-05	180	88	5	42f48e646fc6e72ad3cce72409ace3a0b64020a2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KIF15 BARD1 TLN2 CIT KIF11	2.90e-05	180	88	5	1c1b25f1d22518db5469707131510daae84716a3
ToppCell	droplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASD1 MYO1B SHC3 CNN1 NOTCH3	2.90e-05	180	88	5	78fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PSAT1 KIF15 BARD1 CIT KIF11	2.98e-05	181	88	5	cf13bf7a531a2d40f8d778629cf2431b684f65f3
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PSAT1 KIF15 BARD1 CIT KIF11	2.98e-05	181	88	5	74311aac2fe27dc02a9be3bc20e0c7ef1c239049
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	KIF15 CD38 RNF213 N4BP3 KIF11	3.06e-05	182	88	5	ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|tumor_Lung / Location, Cell class and cell subclass	PRRX1 MYO1B PCDH1 CNN1 NOTCH3	3.14e-05	183	88	5	a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	KIF15 BARD1 MICAL3 CIT KIF11	3.31e-05	185	88	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	SLFN12L NOMO2 RNF213 STX12 INVS	3.40e-05	186	88	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	COPD-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	RASD1 MYO1B PCDH1 HSPA2 NOTCH3	3.48e-05	187	88	5	406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative\|Multiple_Sclerosis / Disease, Lineage and Cell Type	PSAT1 KIF15 BARD1 CIT KIF11	3.57e-05	188	88	5	6c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRRX1 LAMB2 MYO1B CNN1 NOTCH3	3.66e-05	189	88	5	1ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF15 NAV2 BARD1 CIT KIF11	3.66e-05	189	88	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	PDS5B KIF15 MSH2 CIT KIF11	3.76e-05	190	88	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUL5 WAPL HOOK1 SYNE2 MYO1B	3.85e-05	191	88	5	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLFN12L KIF15 CD38 SYNE2 KIF11	3.85e-05	191	88	5	912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLFN12L KIF15 BARD1 CIT KIF11	3.85e-05	191	88	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLFN12L KIF15 CD38 SYNE2 KIF11	3.85e-05	191	88	5	77a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUL5 WAPL HOOK1 SYNE2 MYO1B	3.85e-05	191	88	5	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUL5 WAPL HOOK1 SYNE2 MYO1B	3.85e-05	191	88	5	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-smooth_muscle_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASD1 MYO1B SHC3 CNN1 NOTCH3	3.95e-05	192	88	5	88472b99970ba0decbf87164fc241a1c77b3b389
ToppCell	Control-Lymphoid-Proliferating_CD4_T_cells\|Control / Condition, Lineage and Cell class	KIF15 NAV2 BARD1 CIT KIF11	4.05e-05	193	88	5	33d409d6ed1c606337248587ad997ac5f67f081d
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KIF15 BARD1 MSH2 CIT KIF11	4.05e-05	193	88	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KIF15 NAV2 CIT CNN1 KIF11	4.05e-05	193	88	5	516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDS5B KIF15 CD38 NIPBL KIF11	4.15e-05	194	88	5	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	SLFN12L KIF15 CD38 BARD1 KIF11	4.25e-05	195	88	5	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	KIF15 CD38 PYGL CIT KIF11	4.25e-05	195	88	5	751cb00b0f3005be6b645adadfbb9dd2215b6e08
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	SLFN12L KIF15 BARD1 CIT KIF11	4.25e-05	195	88	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF15 NAV2 BARD1 CIT KIF11	4.36e-05	196	88	5	6d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF15 NAV2 BARD1 CIT KIF11	4.36e-05	196	88	5	bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIF15 NAV2 BARD1 CIT KIF11	4.36e-05	196	88	5	3dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF15 NAV2 BARD1 CIT KIF11	4.36e-05	196	88	5	4f649e3bfd21f21682678828673843a7d51c4ff2
ToppCell	BAL-Control-Myeloid-Myeloid\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF15 NAV2 BARD1 CIT KIF11	4.36e-05	196	88	5	799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCell	BAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF15 NAV2 BARD1 CIT KIF11	4.36e-05	196	88	5	0c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCell	Control-Myeloid-proliferating_Myeloid_cells\|Control / Disease group,lineage and cell class （2021.01.30）	KIF15 NAV2 BARD1 CIT KIF11	4.46e-05	197	88	5	ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCell	Healthy_Control-Lymphoid-T-Proliferating_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	KIF15 NAV2 BARD1 CIT KIF11	4.46e-05	197	88	5	3ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCell	COVID-19_Severe-NK_activated\|World / disease group, cell group and cell class	SLFN12L RAB8B CD38 SYNE2 RNF213	4.46e-05	197	88	5	a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCell	10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	KIF15 CD38 SYNE2 RASD1 KIF11	4.57e-05	198	88	5	8aa4149d2c1cec73cfd654db093252ec8ec5ef68
ToppCell	severe_COVID-19-NK\|World / disease group, cell group and cell class (v2)	SLFN12L CD38 SYNE2 RNF213 N4BP3	4.57e-05	198	88	5	36b1370ef68c4bbe0268933a6ef5e6022d992bdf
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	PPIG SYNE2 CDC27 NIPBL RAD50	4.57e-05	198	88	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	SYNE2 TOGARAM1 CDC27 NIPBL RAD50	4.68e-05	199	88	5	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIF15 SYNE2 MSH2 CIT KIF11	4.68e-05	199	88	5	305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SOX6 EPS8L2 SYNE2 NAV2 MYO1B	4.68e-05	199	88	5	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	PPIG SYNE2 CDC27 NIPBL RAD50	4.68e-05	199	88	5	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	PPIG SYNE2 CDC27 NIPBL RAD50	4.68e-05	199	88	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-pre_pro_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	KIF15 CD38 SYNE2 RASD1 KIF11	4.68e-05	199	88	5	8e7f9312dec1e3a92b6a0ccc7baa2d46e89c11f3
ToppCell	COVID-19_Severe-immature_Neutrophil\|COVID-19_Severe / Disease condition and Cell class	SYNE2 NAV2 PYGL CIT KIF11	4.68e-05	199	88	5	f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF15 SYNE2 MSH2 CIT KIF11	4.68e-05	199	88	5	fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIF15 BARD1 MSH2 CIT KIF11	4.68e-05	199	88	5	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	COVID-19_Severe-immature_Neutrophil-\|COVID-19_Severe / Disease condition and Cell class	SYNE2 NAV2 PYGL CIT KIF11	4.68e-05	199	88	5	42ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCell	distal-2-mesenchymal-Airway_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 PRRX1 HSPA2 CNN1 NOTCH3	4.68e-05	199	88	5	af226a6c50747dad9ca696463e715913b3ac17c0
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SOX6 SEL1L2 HSPA2 CNN1 NOTCH3	4.68e-05	199	88	5	2ed10c5e15c9d5ed0a8bea580842348d5698a07b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIF15 SYNE2 NAV2 CTNNA2 KIF11	4.68e-05	199	88	5	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF15 SYNE2 NAV2 BARD1 KIF11	4.68e-05	199	88	5	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSAT1 KIF15 BARD1 CIT KIF11	4.68e-05	199	88	5	616c04b0605907fb218263f2164c36cb2fa26b87
ToppCell	Sepsis-URO-Lymphocyte-B-Plasmablast\|URO / Disease, condition lineage and cell class	EPS8L2 CD38 RASD1 MSH2 ARMCX4	4.68e-05	199	88	5	0df6cafb7f3b607cbe80b6f25b4fd62d421d01ee
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SOX6 KIF15 KIF11 DYRK3 SLC16A10	4.79e-05	200	88	5	f100edfd2b3b742458cbbf34de9c403c4d272d3c
ToppCell	distal-1-mesenchymal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRRX1 RASD1 HSPA2 CNN1 NOTCH3	4.79e-05	200	88	5	7623f82bd85a0ff7e2097e9281551208dfc602a8
ToppCell	distal-2-mesenchymal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PRRX1 MYO1B HSPA2 CNN1 NOTCH3	4.79e-05	200	88	5	65a50f03b0027ccefb51b8f77afa283d4a3b3567
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PSAT1 KIF15 CD38 CIT KIF11	4.79e-05	200	88	5	562309f9ca4a73cea5ed1d85b516891545f3ae5f
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-T/NK_proliferative\|Multiple_Sclerosis / Disease, condition lineage and cell class	PSAT1 KIF15 BARD1 CIT KIF11	4.79e-05	200	88	5	7faf1e37364203a08d2b2544979e848b41e36b1c
ToppCell	distal-mesenchymal-Airway_Smooth_Muscle-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SOX6 MYO1B HSPA2 CNN1 NOTCH3	4.79e-05	200	88	5	f09eaa52e11262ec47f3dcb4d890e240eaaa2b3d
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	PIK3CD RAB8B NAV2 HSPA2 STX12 DYRK3 SLC16A10	6.13e-06	179	88	7	5336_UP
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	PDS5B WAPL KIF15 NSD1 BARD1 NIPBL KIF11	7.09e-06	183	88	7	7498_DN
Drug	Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A	PDS5B RALB DCTN1 NIPBL SNX1 NOTCH3 HMG20B	1.15e-05	197	88	7	6212_DN
Disease	Breast Cancer, Familial	BARD1 MSH2 RAD50	9.17e-05	30	86	3	C0346153
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	HOOK1 SYNE2	5.44e-04	12	86	2	DOID:11726 (implicated_via_orthology)
Disease	Hereditary Breast and Ovarian Cancer Syndrome	BARD1 RAD50	7.47e-04	14	86	2	C0677776
Disease	Malignant neoplasm of breast	CUL5 KMT2D HOOK1 SYNE2 BARD1 HADHB CDC27 NIPBL NOTCH3 STX12	1.13e-03	1074	86	10	C0006142
Disease	cancer (implicated_via_orthology)	PIK3CD MSH2 NIPBL NOTCH3 STX12	1.14e-03	268	86	5	DOID:162 (implicated_via_orthology)
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	BARD1 MSH2	1.39e-03	19	86	2	C2936783
Disease	systemising measurement	TSHZ3 PIK3CD	1.70e-03	21	86	2	EFO_0010221
Disease	transitional cell carcinoma (is_implicated_in)	MSH2 RAD50	1.87e-03	22	86	2	DOID:2671 (is_implicated_in)
Disease	Hepatitis	PDS5B NAV2	1.87e-03	22	86	2	HP_0012115
Disease	cotinine measurement	SEL1L2 CTNNA2	2.04e-03	23	86	2	EFO_0007813
Disease	Prostatic Neoplasms	PRRX1 KMT2D PIK3CD RASD1 LAMB2 TLR6 CDC27	2.16e-03	616	86	7	C0033578
Disease	Malignant neoplasm of prostate	PRRX1 KMT2D PIK3CD RASD1 LAMB2 TLR6 CDC27	2.16e-03	616	86	7	C0376358
Disease	antiphospholipid antibody measurement	MICAL3 CNN1	2.41e-03	25	86	2	EFO_0005200
Disease	breast cancer (implicated_via_orthology)	BARD1 RAD50	2.41e-03	25	86	2	DOID:1612 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	EPS8L2 PIK3CD NOTCH3 RYR3	2.57e-03	195	86	4	DOID:1574 (implicated_via_orthology)
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	BARD1 MSH2	2.61e-03	26	86	2	C0009405
Disease	Hereditary non-polyposis colorectal cancer syndrome	BARD1 MSH2	2.81e-03	27	86	2	C1112155
Disease	retinitis pigmentosa (implicated_via_orthology)	POC5 SNRNP200	2.81e-03	27	86	2	DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSLLNFSDAKMNLSS	CEACAM18	271	A8MTB9
SLFNDAGNKKNSIKM	BARD1	131	Q99728
MATSNLLKNKGSLQF	CUL5	1	Q93034
NSILKGAQMKASLAS	DCTN1	1111	Q14203
KEAADMLKALQGASQ	DNM1L	711	O00429
AFAVALKANSSMSEK	ANKRD18B	906	A2A2Z9
GFNKSANIKTVLDSM	BBS12	371	Q6ZW61
KLVDFGSAAKMNSNK	CIT	236	O14578
LNKAKSMGQRLSLIS	HADHB	186	P55084
AMTKAGAKANLRANS	ARMCX4	426	Q5H9R4
VMLNGSRSKIFDKNS	CD38	206	P28907
AKNAAKDMNGTSLHG	RBMY1F	61	Q15415
MAANKSKGQSSLALH	RALB	1	P11234
LNMNLSSNSAKKELG	RBM44	636	Q6ZP01
LAKMFGAKDSELASQ	PDS5B	296	Q9NTI5
ADTNQMLSLSKKALA	NSD1	2256	Q96L73
KRSLQLSGKVNAMTF	NOMO3	531	P69849
ISAKKNSSLDQMFRA	RASD1	176	Q9Y272
KSSKQRAMLAGATAV	RAD50	651	Q92878
TKLNRKMNDSNSAGA	RAB8B	171	Q92930
ASESLKGNMAAFLKN	INTS8	431	Q75QN2
AKVAMLSGALENAKA	POC5	321	Q8NA72
KRSLQLSGKVNAMTF	NOMO2	531	Q5JPE7
KDLEAAMLSKGFSLN	MICAL3	1986	Q7RTP6
QLNMLTEASKKHSGL	KIF15	1071	Q9NS87
MSLLAAKASGELASN	NRAP	566	Q86VF7
KGAAKRTTAATLMNA	KIF11	216	P52732
LSMSLNKDSAKVGAL	LMAN1L	371	Q9HAT1
AMTKDNNLLGKFDLT	HSPA2	451	P54652
KMAANFLSGRKSISF	OR2V1	81	Q8NHB1
KMAANFLSGRKSISF	OR2V2	81	Q96R30
AGLQKSLKFNLMSDA	PCDH1	931	Q08174
AAKFGSLAKQNSQMI	MYO18A	121	Q92614
QLMNSSGSHKDLAGK	COPS4	11	Q9BT78
SLLKKFNSTQIAAMA	GXYLT1	231	Q4G148
SANKKMGSSSENLLS	LRRC31	346	Q6UY01
GSNLLQSFKESMVKD	NIPBL	2461	Q6KC79
KRSLQLSGKVNAMTF	NOMO1	531	Q15155
LALLKNGANKDMQDS	NOTCH3	1956	Q9UM47
DKSMSGNKFQAISLG	DNAH12	2516	Q6ZR08
SKHMANQRALGKLSA	LAMB2	1381	P55268
TLANNELKSLTSKFM	LRRC20	56	Q8TCA0
LTMQKAFLEKQQSGS	EPS8L2	681	Q9H6S3
AKNMFAISKQGSNLV	ETAA1	676	Q9NY74
KEFLLSMANRGKDTN	PPIG	106	Q13427
NLSSKLMEFNLGTDK	EXOC5	316	O00471
GALKKNATMLYTASQ	CTNNA2	211	P26232
KATGNKNTLAVHLMA	EN2	301	P19622
NKSLAFQKLGMESRL	HOOK1	671	Q9UJC3
AFNLQKAAAEGLMSL	CDC27	451	P30260
GAKNLQSVVLSKMNF	MSH2	71	P43246
IANKLKANLMSETNG	DYRK3	561	O43781
MNKSENLLFAGSSLA	INVS	1	Q9Y283
SKANFSISRMKQDLA	KIR2DS1	81	Q14954
SAQSRGAKNSVSLMK	OR10J3	301	Q5JRS4
KKEDSSSGLMNTLLN	HMG20B	156	Q9P0W2
NLMKLNSHLSAASKG	MEIOC	496	A2RUB1
MDLQKKQSNLATGLS	SH3D19	371	Q5HYK7
MGDQLIKASNKSRAA	SYNE2	5976	Q8WXH0
ANGHLLLNSEKMSKS	LARS1	706	Q9P2J5
LLNSEKMSKSTGNFL	LARS1	711	Q9P2J5
LKAAKAGSANAMAFI	SEL1L2	326	Q5TEA6
NGGAAAMEKLSSIKS	PSAT1	261	Q9Y617
KKQSGSAAGLAMITA	NAV2	1146	Q8IVL1
SKMLSSILGKSNLQF	SHC3	206	Q92529
RMSEAQSKLLNKGAS	OR6T1	261	Q8NGN1
AGMDKQAKLSDLQTA	SLC25A2	96	Q9BXI2
LKSKAMDLAQAGSTV	RRP12	596	Q5JTH9
AEGSKAMNGSAAKLQ	SOX6	576	P35712
QSTLLALASMAKTKG	CNN1	121	P51911
AMLLAQLNAFLSKSS	RNF213	2656	Q63HN8
ALNTAQFAKSLAMLG	SNX1	341	Q13596
SAKVMNASAALEFLK	SLFN12L	151	Q6IEE8
INNLAFLTGDSKSKM	RYR3	3321	Q15413
LMSQLGTKQDSSKLQ	STX12	46	Q86Y82
QAKLGTKLISMFNQS	UBE3D	86	Q7Z6J8
FDKLMDGTSQALAKA	WAPL	311	Q7Z5K2
KSNMAATAAFNKDAL	PIK3CD	841	O00329
FKMSNSLAEKAAVAT	TSHZ3	751	Q63HK5
SQLNFLGLSAMKLQK	TLR6	146	Q9Y2C9
SANLVASGELMSSKK	SNRNP200	241	O75643
NLKNISMASSKLLLA	TLN2	1306	Q9Y4G6
TATAKLSKALFAQMG	TOGARAM1	1676	Q9Y4F4
NGEDMSKFLKLNSHI	UGGT2	416	Q9NYU1
MLANKNASLLKSYSG	PRRX1	156	P54821
MVLKNIAASGKFSSD	PYGL	801	P06737
QNSLLSSSSGMFKKE	SLC16A10	496	Q8TF71
LTVSAAAAKNLNGVM	KMT2D	4786	O14686
GSQFKASVATLMKNL	MYO1B	571	O43795
KGFLSMQSLASHKGQ	N4BP3	126	O15049