Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	zinc ion binding	ZNF346 TRAF5 TRAF6 ZNF276 THRB ADAMTS9 KDM5A RCHY1 NFXL1 FBXO11 ADAM30 EP300 ZRANB3	2.29e-06	891	61	13	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	ZNF346 TRAF5 TRAF6 ZNF276 THRB ADAMTS9 KDM5A RCHY1 NFXL1 FBXO11 ADAM30 EP300 ZRANB3	4.99e-05	1189	61	13	GO:0046914
GeneOntologyMolecularFunction	hormone binding	THRB EGFR AVPR1A ABHD2	2.78e-04	103	61	4	GO:0042562
GeneOntologyBiologicalProcess	limb development	FRAS1 FBN2 ITGA6 LRP5 CPLANE1 NOTCH2	4.71e-05	224	60	6	GO:0060173
GeneOntologyBiologicalProcess	appendage development	FRAS1 FBN2 ITGA6 LRP5 CPLANE1 NOTCH2	4.71e-05	224	60	6	GO:0048736
GeneOntologyBiologicalProcess	negative regulation of female receptivity	THRB AVPR1A	4.97e-05	4	60	2	GO:0007621
GeneOntologyBiologicalProcess	animal organ morphogenesis	VEGFC FRAS1 TRAF6 FBN2 THRB EGFR ADAMTS9 ITGA6 LRP5 TECTA USH2A EP300 NOTCH2	5.82e-05	1269	60	13	GO:0009887
GeneOntologyBiologicalProcess	embryonic limb morphogenesis	FRAS1 FBN2 LRP5 CPLANE1 NOTCH2	7.07e-05	148	60	5	GO:0030326
GeneOntologyBiologicalProcess	embryonic appendage morphogenesis	FRAS1 FBN2 LRP5 CPLANE1 NOTCH2	7.07e-05	148	60	5	GO:0035113
GeneOntologyBiologicalProcess	positive regulation of fibrinolysis	KLKB1 F11	8.27e-05	5	60	2	GO:0051919
GeneOntologyBiologicalProcess	appendage morphogenesis	FRAS1 FBN2 LRP5 CPLANE1 NOTCH2	2.01e-04	185	60	5	GO:0035107
GeneOntologyBiologicalProcess	limb morphogenesis	FRAS1 FBN2 LRP5 CPLANE1 NOTCH2	2.01e-04	185	60	5	GO:0035108
GeneOntologyCellularComponent	receptor complex	TRAF5 TRAF6 EGFR PLXNC1 ITGA6 GABRQ LRP5 LRP1B NOTCH2	5.08e-05	581	62	9	GO:0043235
GeneOntologyCellularComponent	FACT complex	MMS22L TONSL	5.17e-05	4	62	2	GO:0035101
GeneOntologyCellularComponent	nuclear replication fork	MMS22L TONSL ZRANB3	2.63e-04	42	62	3	GO:0043596
GeneOntologyCellularComponent	CD40 receptor complex	TRAF5 TRAF6	4.68e-04	11	62	2	GO:0035631
GeneOntologyCellularComponent	MCM complex	MMS22L TONSL	4.68e-04	11	62	2	GO:0042555
Domain	EGF-like_dom	FRAS1 FBN2 DNER LRP5 ADAM30 HABP2 TECTA LRP1B NOTCH2 SORL1	7.36e-09	249	61	10	IPR000742
Domain	EGF	FRAS1 FBN2 DNER LRP5 HABP2 TECTA LRP1B NOTCH2 SORL1	6.66e-08	235	61	9	SM00181
Domain	EGF_3	FBN2 DNER LRP5 ADAM30 HABP2 LRP1B NOTCH2 SORL1	9.25e-07	235	61	8	PS50026
Domain	EGF_1	FBN2 DNER LRP5 ADAM30 HABP2 USH2A LRP1B NOTCH2	1.71e-06	255	61	8	PS00022
Domain	EGF-like_CS	FBN2 DNER LRP5 ADAM30 HABP2 LRP1B NOTCH2 SORL1	2.03e-06	261	61	8	IPR013032
Domain	EGF_2	FBN2 DNER LRP5 ADAM30 HABP2 LRP1B NOTCH2 SORL1	2.27e-06	265	61	8	PS01186
Domain	EGF-like_Ca-bd_dom	FBN2 DNER LRP5 HABP2 LRP1B NOTCH2	3.12e-06	124	61	6	IPR001881
Domain	EGF	DNER LRP5 HABP2 TECTA LRP1B NOTCH2	3.43e-06	126	61	6	PF00008
Domain	APPLE	KLKB1 F11	1.05e-05	2	61	2	SM00223
Domain	APPLE	KLKB1 F11	1.05e-05	2	61	2	PS00495
Domain	Apple	KLKB1 F11	1.05e-05	2	61	2	IPR000177
Domain	Growth_fac_rcpt_	FRAS1 FBN2 EGFR DNER LRP1B NOTCH2	1.17e-05	156	61	6	IPR009030
Domain	Ldl_recept_b	LRP5 LRP1B SORL1	1.18e-05	14	61	3	PF00058
Domain	LDLRB	LRP5 LRP1B SORL1	1.18e-05	14	61	3	PS51120
Domain	LY	LRP5 LRP1B SORL1	1.47e-05	15	61	3	SM00135
Domain	LDLR_classB_rpt	LRP5 LRP1B SORL1	1.47e-05	15	61	3	IPR000033
Domain	EGF_CA	FBN2 DNER LRP5 LRP1B NOTCH2	1.78e-05	99	61	5	PS01187
Domain	EGF_CA	FBN2 DNER HABP2 LRP1B NOTCH2	4.86e-05	122	61	5	SM00179
Domain	hEGF	FBN2 DNER NOTCH2	1.02e-04	28	61	3	PF12661
Domain	TNF_rcpt--assoc_TRAF	TRAF5 TRAF6	1.56e-04	6	61	2	IPR012227
Domain	PAN	KLKB1 F11	2.18e-04	7	61	2	PS50948
Domain	Pan_app	KLKB1 F11	2.18e-04	7	61	2	IPR003609
Domain	PAN_1	KLKB1 F11	2.18e-04	7	61	2	PF00024
Domain	-	LRP5 LRP1B SORL1	2.79e-04	39	61	3	2.120.10.30
Domain	EGF_Ca-bd_CS	FBN2 DNER LRP1B NOTCH2	2.84e-04	97	61	4	IPR018097
Domain	zf-TRAF	TRAF5 TRAF6	2.90e-04	8	61	2	PF02176
Domain	LDLR_class-A_CS	LRP5 LRP1B SORL1	3.00e-04	40	61	3	IPR023415
Domain	ASX_HYDROXYL	FBN2 DNER LRP1B NOTCH2	3.19e-04	100	61	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN2 DNER LRP1B NOTCH2	3.99e-04	106	61	4	IPR000152
Domain	Ldl_recept_a	LRP5 LRP1B SORL1	4.27e-04	45	61	3	PF00057
Domain	-	LRP5 LRP1B SORL1	4.55e-04	46	61	3	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	LRP5 LRP1B SORL1	4.55e-04	46	61	3	IPR011042
Domain	LDLRA_1	LRP5 LRP1B SORL1	5.16e-04	48	61	3	PS01209
Domain	LDLRA_2	LRP5 LRP1B SORL1	5.49e-04	49	61	3	PS50068
Domain	LDrepeatLR_classA_rpt	LRP5 LRP1B SORL1	5.49e-04	49	61	3	IPR002172
Domain	LDLa	LRP5 LRP1B SORL1	5.49e-04	49	61	3	SM00192
Domain	MATH/TRAF_dom	TRAF5 TRAF6	6.78e-04	12	61	2	IPR002083
Domain	MATH	TRAF5 TRAF6	6.78e-04	12	61	2	PS50144
Domain	MATH	TRAF5 TRAF6	6.78e-04	12	61	2	SM00061
Domain	Znf_TRAF	TRAF5 TRAF6	6.78e-04	12	61	2	IPR001293
Domain	MATH	TRAF5 TRAF6	6.78e-04	12	61	2	PF00917
Domain	ZF_TRAF	TRAF5 TRAF6	8.00e-04	13	61	2	PS50145
Domain	-	TRAF5 TRAF6	9.31e-04	14	61	2	3.90.890.10
Domain	-	TRAF5 TRAF6	9.31e-04	14	61	2	2.60.210.10
Domain	SIAH-type	TRAF5 TRAF6	1.22e-03	16	61	2	IPR013323
Domain	Furin_repeat	FRAS1 EGFR	1.55e-03	18	61	2	IPR006212
Domain	FU	FRAS1 EGFR	1.55e-03	18	61	2	SM00261
Domain	VWC_out	FRAS1 TECTA	1.73e-03	19	61	2	SM00215
Domain	TNFR_c6	TNFRSF8 FAS	2.32e-03	22	61	2	PF00020
Domain	TRAF-like	TRAF5 TRAF6	2.77e-03	24	61	2	IPR008974
Domain	EGF_CA	FBN2 LRP1B NOTCH2	2.80e-03	86	61	3	PF07645
Domain	TRYPSIN_SER	HABP2 KLKB1 F11	3.18e-03	90	61	3	IPR033116
Domain	TNFR	TNFRSF8 FAS	3.24e-03	26	61	2	SM00208
Domain	cEGF	FBN2 LRP1B	3.24e-03	26	61	2	IPR026823
Domain	cEGF	FBN2 LRP1B	3.24e-03	26	61	2	PF12662
Domain	TNFR_NGFR_1	TNFRSF8 FAS	4.02e-03	29	61	2	PS00652
Domain	TNFR_NGFR_2	TNFRSF8 FAS	4.02e-03	29	61	2	PS50050
Pathway	WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING	TRAF5 TRAF6 EGFR FAS	2.42e-05	51	47	4	M39438
Pathway	WP_CANCER_PATHWAYS	VEGFC TRAF5 TRAF6 EGFR ITGA6 LRP5 FAS EP300 NOTCH2	3.77e-05	507	47	9	M48302
Pathway	KEGG_PATHWAYS_IN_CANCER	VEGFC TRAF5 TRAF6 EGFR ITGA6 FAS EP300	9.24e-05	325	47	7	M12868
Pubmed	TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.	TRAF5 TRAF6 TNFRSF8	3.00e-07	8	62	3	10764746
Pubmed	The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A.	TRAF5 TRAF6 FAS	1.52e-06	13	62	3	11035039
Pubmed	Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma.	EGFR PCLO	3.13e-06	2	62	2	28263981
Pubmed	FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.	EGFR FAS	3.13e-06	2	62	2	21430781
Pubmed	The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.	MMS22L TONSL	3.13e-06	2	62	2	21055983
Pubmed	The relative priority of prekallikrein and factors XI/XIa assembly on cultured endothelial cells.	KLKB1 F11	3.13e-06	2	62	2	12944405
Pubmed	MMS22L-TONSL functions in sister chromatid cohesion in a pathway parallel to DSCC1-RFC.	MMS22L TONSL	3.13e-06	2	62	2	36622344
Pubmed	Nucleic acids as cofactors for factor XI and prekallikrein activation: Different roles for high-molecular-weight kininogen.	KLKB1 F11	3.13e-06	2	62	2	28124063
Pubmed	Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein.	KLKB1 F11	3.13e-06	2	62	2	3636155
Pubmed	[Expressions and their significances of vascular endothelial growth factor-c mrna and epidermal growth factor receptor mrna in non-small cell lung cancer tissues and lymph node tissues].	VEGFC EGFR	3.13e-06	2	62	2	21159248
Pubmed	Distinct domains in the adenovirus E3 RIDalpha protein are required for degradation of Fas and the epidermal growth factor receptor.	EGFR FAS	3.13e-06	2	62	2	14557654
Pubmed	PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population.	ADAMTS9 ADAM30 NOTCH2	6.02e-06	20	62	3	19862325
Pubmed	Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.	ADAMTS9 ADAM30 NOTCH2	7.01e-06	21	62	3	18591388
Pubmed	Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.	ADAMTS9 ADAM30 NOTCH2	8.11e-06	22	62	3	18372903
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	FBN2 ADAMTS9 HABP2	9.31e-06	23	62	3	26027930
Pubmed	Expression of hepatocyte epidermal growth factor receptor, FAS and glypican 3 in EpCAM-positive regenerative clusters of hepatocytes, cholangiocytes, and progenitor cells in human liver failure.	EGFR FAS	9.37e-06	3	62	2	23114924
Pubmed	Correlated expression of Fas, NF-kappaB, and VEGF-C in infiltrating ductal carcinoma of the breast.	VEGFC FAS	9.37e-06	3	62	2	23327061
Pubmed	Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype.	EGFR ITGA6	9.37e-06	3	62	2	7618084
Pubmed	Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women.	KLKB1 F11	9.37e-06	3	62	2	24977287
Pubmed	The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1.	TRAF5 TRAF6	9.37e-06	3	62	2	29176576
Pubmed	H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex.	MMS22L TONSL	9.37e-06	3	62	2	27338793
Pubmed	The tyrosine phosphorylated pro-survival form of Fas intensifies the EGF-induced signal in colorectal cancer cells through the nuclear EGFR/STAT3-mediated pathway.	EGFR FAS	9.37e-06	3	62	2	30127519
Pubmed	Impaired recall of CD8 memory T cells in immunologically privileged tissue.	TNFRSF8 FAS	9.37e-06	3	62	2	15661869
Pubmed	Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation.	EGFR FAS	9.37e-06	3	62	2	12586732
Pubmed	The Structure and Ubiquitin Binding Properties of TRAF RING Heterodimers.	TRAF5 TRAF6	9.37e-06	3	62	2	33539883
Pubmed	EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas.	EGFR EP300	9.37e-06	3	62	2	25996283
Pubmed	Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen.	KLKB1 F11	9.37e-06	3	62	2	89876
Pubmed	Studies of binding of prekallikrein and Factor XI to high molecular weight kininogen and its light chain.	KLKB1 F11	9.37e-06	3	62	2	291905
Pubmed	The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95.	EGFR FAS	9.37e-06	3	62	2	15039424
Pubmed	A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain.	KLKB1 F11	9.37e-06	3	62	2	30591525
Pubmed	Genetic variants associated with deep vein thrombosis: the F11 locus.	KLKB1 F11	9.37e-06	3	62	2	19583818
Pubmed	TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer.	TRAF6 EP300	9.37e-06	3	62	2	21629263
Pubmed	Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells.	TRAF5 TNFRSF8	9.37e-06	3	62	2	11971184
Pubmed	Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.	TRAF5 TNFRSF8	9.37e-06	3	62	2	8999898
Pubmed	Inhibition of integrin-mediated crosstalk with epidermal growth factor receptor/Erk or Src signaling pathways in autophagic prostate epithelial cells induces caspase-independent death.	EGFR ITGA6	9.37e-06	3	62	2	17475774
Pubmed	B cell maturation protein is a receptor for the tumor necrosis factor family member TALL-1.	TRAF5 TRAF6	1.87e-05	4	62	2	10908663
Pubmed	TRAF family proteins link PKR with NF-kappa B activation.	TRAF5 TRAF6	1.87e-05	4	62	2	15121867
Pubmed	EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.	TRAF6 EGFR	1.87e-05	4	62	2	25061874
Pubmed	Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation.	TRAF5 TRAF6	1.87e-05	4	62	2	22593207
Pubmed	Osteocalcin triggers Fas/FasL-mediated necroptosis in adipocytes via activation of p300.	FAS EP300	1.87e-05	4	62	2	30546087
Pubmed	Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics.	FBN2 EGFR	1.87e-05	4	62	2	19469909
Pubmed	Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).	TRAF5 TNFRSF8	1.87e-05	4	62	2	9511754
Pubmed	Inactivation of human plasma kallikrein and factor XIa by protein C inhibitor.	KLKB1 F11	1.87e-05	4	62	2	2844223
Pubmed	The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress.	MMS22L TONSL	1.87e-05	4	62	2	27797818
Pubmed	Inhibitory properties of a novel human Kunitz-type protease inhibitor homologous to tissue factor pathway inhibitor.	KLKB1 F11	1.87e-05	4	62	2	8555184
Pubmed	Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway.	EGFR EP300	1.87e-05	4	62	2	28759294
Pubmed	N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.	EGFR ITGA6	1.87e-05	4	62	2	27641064
Pubmed	Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase.	TRAF5 TRAF6	1.87e-05	4	62	2	9685412
Pubmed	Enterovirus 71 modulates a COX-2/PGE2/cAMP-dependent viral replication in human neuroblastoma cells: role of the c-Src/EGFR/p42/p44 MAPK/CREB signaling pathway.	EGFR EP300	1.87e-05	4	62	2	21268077
Pubmed	MLN4924 protects against interleukin-17A-induced pulmonary inflammation by disrupting ACT1-mediated signaling.	TRAF5 TRAF6	1.87e-05	4	62	2	30892082
Pubmed	The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation.	TRAF5 TRAF6	1.87e-05	4	62	2	21822257
Pubmed	Integrin α6β4 Promotes Autocrine Epidermal Growth Factor Receptor (EGFR) Signaling to Stimulate Migration and Invasion toward Hepatocyte Growth Factor (HGF).	EGFR ITGA6	1.87e-05	4	62	2	26381405
Pubmed	Two distinct transport motifs in the adenovirus E3/10.4-14.5 proteins act in concert to down-modulate apoptosis receptors and the epidermal growth factor receptor.	EGFR FAS	1.87e-05	4	62	2	14506242
Pubmed	Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut.	TRAF5 TRAF6 TNFRSF8 FAS	2.58e-05	95	62	4	20568250
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5A EZH1 EP300	2.83e-05	33	62	3	26864203
Pubmed	Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer.	EGFR FAS	3.12e-05	5	62	2	17912028
Pubmed	The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells.	MMS22L TONSL	3.12e-05	5	62	2	29478807
Pubmed	Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands.	EGFR DNER	3.12e-05	5	62	2	15965977
Pubmed	TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.	TRAF5 TRAF6	3.12e-05	5	62	2	17332487
Pubmed	TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer.	TRAF6 LRP5	3.12e-05	5	62	2	31262711
Pubmed	Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1).	TRAF5 TRAF6	3.12e-05	5	62	2	10523862
Pubmed	Two differently regulated nuclear factor kappaB activation pathways triggered by the cytoplasmic tail of CD40.	TRAF5 TRAF6	3.12e-05	5	62	2	9990007
Pubmed	TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.	TRAF6 EP300	3.12e-05	5	62	2	27818144
Pubmed	Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice.	TRAF5 TRAF6	3.12e-05	5	62	2	11882293
Pubmed	Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease.	KLKB1 F11	3.12e-05	5	62	2	10962009
Pubmed	Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif.	TRAF5 TRAF6	3.12e-05	5	62	2	10075662
Pubmed	Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa.	KLKB1 F11	3.12e-05	5	62	2	12372819
Pubmed	RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.	TRAF5 TRAF6	3.12e-05	5	62	2	29661858
Pubmed	The polyphosphate-factor XII pathway drives coagulation in prostate cancer-associated thrombosis.	KLKB1 F11	3.12e-05	5	62	2	26153520
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	EGFR GABRQ LRP1B NOTCH2	3.28e-05	101	62	4	23382219
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	ZNF346 PPP2R5A FBXO11 EXOC2 CMC4 EP300 NOTCH2	4.53e-05	533	62	7	25544563
Pubmed	Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling.	TRAF5 TRAF6	4.67e-05	6	62	2	21041727
Pubmed	Testing the association of novel meta-analysis-derived diabetes risk genes with type II diabetes and related metabolic traits in Asian Indian Sikhs.	ADAMTS9 NOTCH2	4.67e-05	6	62	2	19247373
Pubmed	Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).	TRAF5 TRAF6	4.67e-05	6	62	2	11435475
Pubmed	BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.	TRAF5 TRAF6	4.67e-05	6	62	2	20138174
Pubmed	Tumor necrosis factor receptor-associated factors (TRAFs).	TRAF5 TRAF6	4.67e-05	6	62	2	11607847
Pubmed	Notch controls the magnitude of T helper cell responses by promoting cellular longevity.	FAS NOTCH2	4.67e-05	6	62	2	22615412
Pubmed	TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB.	TRAF5 TRAF6	4.67e-05	6	62	2	12296995
Pubmed	BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS.	TRAF5 TRAF6	4.67e-05	6	62	2	36045679
Pubmed	The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators.	TRAF5 TRAF6	4.67e-05	6	62	2	11384837
Pubmed	Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.	ADAMTS9 NOTCH2	4.67e-05	6	62	2	18567820
Pubmed	Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.	TRAF5 TRAF6	4.67e-05	6	62	2	19937093
Pubmed	Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase.	TRAF5 TRAF6	4.67e-05	6	62	2	10025951
Pubmed	Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.	TRAF6 NOTCH2	4.67e-05	6	62	2	29228365
Pubmed	Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.	TRAF5 TRAF6	4.67e-05	6	62	2	9275204
Pubmed	The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily.	TRAF5 TRAF6	4.67e-05	6	62	2	9852070
Pubmed	Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit.	EGFR ITGA6	4.67e-05	6	62	2	9022052
Pubmed	Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis.	TRAF5 TRAF6	4.67e-05	6	62	2	16147974
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	FRAS1 FBN2 EGFR NAGA DNER ITGA6 LRP5 LRP1B NOTCH2 SORL1	4.88e-05	1201	62	10	35696571
Pubmed	Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms.	ADAMTS9 OASL NOTCH2	5.48e-05	41	62	3	20889853
Pubmed	Hepatitis B Virus-Induced Parkin-Dependent Recruitment of Linear Ubiquitin Assembly Complex (LUBAC) to Mitochondria and Attenuation of Innate Immunity.	TRAF5 TRAF6	6.53e-05	7	62	2	27348524
Pubmed	HIV-1 Nef interacts with HCV Core, recruits TRAF2, TRAF5 and TRAF6, and stimulates HIV-1 replication in macrophages.	TRAF5 TRAF6	6.53e-05	7	62	2	23774506
Pubmed	Identification of the MMS22L-TONSL complex that promotes homologous recombination.	MMS22L TONSL	6.53e-05	7	62	2	21055984
Pubmed	An additional region of coactivator GRIP1 required for interaction with the hormone-binding domains of a subset of nuclear receptors.	THRB EP300	6.53e-05	7	62	2	9920895
Pubmed	The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor.	TRAF5 TRAF6	6.53e-05	7	62	2	9774460
Pubmed	Purification and characterization of plasma protein C inhibitor.	KLKB1 F11	6.53e-05	7	62	2	2551064
Pubmed	TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation.	TRAF5 TRAF6	6.53e-05	7	62	2	10880535
Pubmed	Interaction of estrogen receptor alpha with 3-methyladenine DNA glycosylase modulates transcription and DNA repair.	THRB EP300	6.53e-05	7	62	2	14761960
Pubmed	CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization.	TRAF5 TRAF6	6.53e-05	7	62	2	9718306
Pubmed	SNX5 inhibits RLR-mediated antiviral signaling by targeting RIG-I-VISA signalosome.	TRAF5 TRAF6	6.53e-05	7	62	2	31806368
Interaction	NTN5 interactions	FRAS1 FBN2 LRP1B NOTCH2 SORL1	9.50e-09	24	62	5	int:NTN5
Interaction	IGFL3 interactions	FRAS1 FBN2 LRP5 LRP1B NOTCH2 SORL1	1.13e-07	75	62	6	int:IGFL3
Interaction	FOXD4L6 interactions	FBN2 EGFR LRP1B NOTCH2 SORL1	4.02e-07	49	62	5	int:FOXD4L6
Interaction	ZFP41 interactions	FRAS1 FBN2 LRP1B NOTCH2 SORL1	8.66e-07	57	62	5	int:ZFP41
Interaction	FBN2 interactions	FBN2 THRB EGFR KLKB1 NOTCH2	1.68e-06	65	62	5	int:FBN2
Interaction	FBXO2 interactions	FRAS1 FBN2 EGFR PLXNC1 SPRING1 ITGA6 LRP1B NOTCH2 SORL1	4.36e-06	411	62	9	int:FBXO2
Interaction	TIMP3 interactions	FRAS1 LRP5 LRP1B NOTCH2 SORL1	8.41e-06	90	62	5	int:TIMP3
Interaction	TFPI2 interactions	EGFR KLKB1 F11 SORL1	9.16e-06	43	62	4	int:TFPI2
Interaction	ROBO4 interactions	THRB EGFR EP300	9.85e-06	14	62	3	int:ROBO4
Interaction	EDN3 interactions	NAGA LRP5 FBXO11 NOTCH2 SORL1	2.04e-05	108	62	5	int:EDN3
Interaction	CCN6 interactions	FRAS1 NOTCH2 SORL1	2.59e-05	19	62	3	int:CCN6
Interaction	PRG2 interactions	FRAS1 FBN2 NAGA ITGA6 LRP5 NOTCH2 SORL1	2.66e-05	285	62	7	int:PRG2
Interaction	ZNF224 interactions	FBN2 LRP1B SORL1	3.05e-05	20	62	3	int:ZNF224
Interaction	TAFAZZIN interactions	FRAS1 SPRING1 NAGA LRP5 LRP1B SORL1	4.16e-05	207	62	6	int:TAFAZZIN
Interaction	DYRK1A interactions	ADAMTS9 SPRING1 LPP TONSL KPRP LRBA LRP1B EP300 NOTCH2	4.53e-05	552	62	9	int:DYRK1A
Interaction	GET1 interactions	THRB EGFR FAS EP300	5.71e-05	68	62	4	int:GET1
Interaction	TNFRSF11A interactions	TRAF5 TRAF6 EGFR	6.85e-05	26	62	3	int:TNFRSF11A
Interaction	ZNF408 interactions	FRAS1 FBN2 LRP1B NOTCH2 SORL1	8.37e-05	145	62	5	int:ZNF408
Interaction	TRAIP interactions	TRAF5 TRAF6 EGFR TNFRSF8	9.29e-05	77	62	4	int:TRAIP
Interaction	NMS interactions	FRAS1 LRP5 LRP1B	1.06e-04	30	62	3	int:NMS
Interaction	STAT2 interactions	LIPT1 EGFR FBXO11 EP300	1.13e-04	81	62	4	int:STAT2
Interaction	ADAMTS9 interactions	ADAMTS9 NOTCH2	1.39e-04	6	62	2	int:ADAMTS9
Interaction	SIRPD interactions	FRAS1 NAGA LRP5 SORL1	1.43e-04	86	62	4	int:SIRPD
Interaction	NDP interactions	LRP5 LRP1B SORL1	1.69e-04	35	62	3	int:NDP
Interaction	GREM2 interactions	FBN2 NOTCH2 SORL1	2.00e-04	37	62	3	int:GREM2
Interaction	POP1 interactions	ZNF346 EGFR OASL FAM76B EP300 SORL1	2.06e-04	277	62	6	int:POP1
Interaction	NTRK2 interactions	TRAF6 EGFR LRBA NOTCH2 SORL1	2.08e-04	176	62	5	int:NTRK2
Interaction	TRAF3 interactions	TRAF5 TRAF6 EGFR TNFRSF8 KPRP FAS	2.10e-04	278	62	6	int:TRAF3
Cytoband	4q35	KLKB1 F11	1.86e-04	15	62	2	4q35
Cytoband	Ensembl 112 genes in cytogenetic band chr1p12	ADAM30 NOTCH2	2.37e-03	53	62	2	chr1p12
GeneFamily	TNF receptor associated factors	TRAF5 TRAF6	8.97e-05	7	38	2	1056
GeneFamily	Low density lipoprotein receptors	LRP5 LRP1B	3.31e-04	13	38	2	634
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF8 FAS	1.68e-03	29	38	2	782
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	PLXNC1 TNFRSF8 ITGA6 FAS	9.14e-03	394	38	4	471
Coexpression	GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN	TRAF5 PPP2R5A CDC42SE2 ITGA6 EZH1 FAS	7.89e-06	200	62	6	M8506
Coexpression	SERVITJA_LIVER_HNF1A_TARGETS_DN	FRAS1 EGFR AFM HABP2 F11	4.64e-05	166	62	5	M2398
Coexpression	DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN	FBN2 NAGA ITGA6 LRP5 EP300 SORL1	4.84e-05	276	62	6	M3063
Coexpression	GARCIA_PINERES_PBMC_HPV_16_L1_VLP_AGE_18_25YO_2MO_DN	PPP2R5A AVPR1A PLXNC1 ITGA6 F11 SORL1	6.01e-05	287	62	6	M40958
Coexpression	MORI_MATURE_B_LYMPHOCYTE_UP	LPP TONSL FAM76B SORL1	7.69e-05	95	62	4	M17083
Coexpression	TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP	THRB EGFR FAM76B SORL1	8.01e-05	96	62	4	M5549
Coexpression	SERVITJA_LIVER_HNF1A_TARGETS_DN	FRAS1 EGFR AFM HABP2 F11	8.79e-05	190	62	5	MM1311
Coexpression	GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP	MDN1 LPP NAGA ITGA6 LRBA	1.04e-04	197	62	5	M7403
Coexpression	GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	LIPT1 TRAF5 PPP2R5A KDM5A SORL1	1.07e-04	198	62	5	M7610
Coexpression	GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP	TRAF5 ZNF276 MDN1 ITGA6 LRBA	1.07e-04	198	62	5	M4478
Coexpression	GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_DN	CERK TRAF6 ZNF276 ITGA6 EZH1	1.09e-04	199	62	5	M9031
Coexpression	GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP	LIPT1 TRAF5 PLXNC1 MLST8 EZH1	1.12e-04	200	62	5	M7031
Coexpression	GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP	TRAF5 CDC42SE2 LPP ITGA6 NOTCH2	1.12e-04	200	62	5	M7841
Coexpression	GSE18893_TCONV_VS_TREG_24H_CULTURE_DN	CERK MMS22L OASL ZRANB3 SORL1	1.12e-04	200	62	5	M7289
Coexpression	GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_DN	C6orf118 SPRING1 FBXO11 EXOC2 CPLANE1	1.12e-04	200	62	5	M7305
Coexpression	GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP	AVPR1A TGFBRAP1 TMEM74 EXOC2 NOTCH2	1.12e-04	200	62	5	M7417
Coexpression	HOFT_CD4_POSITIVE_ALPHA_BETA_MEMORY_T_CELL_BCG_VACCINE_AGE_18_45YO_7DY_UP	MED24 TNFRSF8 TGFBRAP1	1.17e-04	40	62	3	M41068
Coexpression	KONDO_EZH2_TARGETS	EGFR PCLO DNER ITGA6 SORL1	2.10e-04	229	62	5	M5301
Coexpression	JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP	PPP2R5A KDM5A NAGA	2.15e-04	49	62	3	M2202
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 KPRP TECTA USH2A LRP1B KLKB1	1.03e-07	162	62	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 KPRP TECTA USH2A LRP1B	1.81e-06	145	62	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FBN2 TECTA USH2A LRP1B	2.93e-06	160	62	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FBN2 TECTA USH2A LRP1B	2.93e-06	160	62	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 PCLO USH2A LRP1B KLKB1	3.84e-06	169	62	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FBN2 PCLO USH2A LRP1B	5.80e-06	184	62	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FBN2 PCLO USH2A LRP1B	5.80e-06	184	62	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FBN2 PCLO USH2A LRP1B	5.80e-06	184	62	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	4.23e-05	139	62	4	82bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCell	facs-Liver-Hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	4.23e-05	139	62	4	fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	4.23e-05	139	62	4	4ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCell	facs-Liver-Hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	4.23e-05	139	62	4	fc9ac09c2106e88104a52575832d71d17765eec8
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	6.63e-05	156	62	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VEGFC AVPR1A SPRING1 SORL1	7.68e-05	162	62	4	36ddebe3bb172c992739353b7b049b2dde98b559
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK TRAF6 EGFR MLST8	7.86e-05	163	62	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	facs\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF5 KANSL2 NOTCH2 SORL1	9.46e-05	171	62	4	c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell	Tuft-tuft-4\|World / Class top	TRAF5 MDN1 KDM5A OASL	1.01e-04	174	62	4	d6f306ebf66061bf9e9742000bfedce12d277452
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5A EGFR AVPR1A ITGA6	1.10e-04	178	62	4	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5A EGFR AVPR1A ITGA6	1.15e-04	180	62	4	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L C6orf118 TONSL ZRANB3	1.15e-04	180	62	4	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	PLXNC1 RCHY1 TGFBRAP1 LRBA	1.18e-04	181	62	4	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	1.20e-04	182	62	4	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	1.20e-04	182	62	4	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	1.20e-04	182	62	4	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EGFR ADAMTS9 AVPR1A DNER	1.23e-04	183	62	4	6e6128c5be5e0a2db6d84eecbf4dddd02d0216f8
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGFR AFM HABP2 KLKB1	1.23e-04	183	62	4	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EGFR ADAMTS9 AVPR1A DNER	1.23e-04	183	62	4	5e361be3ae3fe05098968e58427630127bd12675
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 EGFR DNER NOTCH2	1.25e-04	184	62	4	e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 EGFR AVPR1A DNER	1.31e-04	186	62	4	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PCLO NFXL1 USH2A LRP1B	1.31e-04	186	62	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VEGFC FRAS1 EGFR ADAMTS9	1.34e-04	187	62	4	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VEGFC FRAS1 EGFR ADAMTS9	1.34e-04	187	62	4	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5A AVPR1A ABHD2 ITGA6	1.34e-04	187	62	4	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VEGFC FRAS1 EGFR ADAMTS9	1.34e-04	187	62	4	08c73d125e0638c9e9878165bba2442c266c8a48
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	PPP2R5A EGFR AVPR1A ITGA6	1.34e-04	187	62	4	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 EGFR AVPR1A DNER	1.36e-04	188	62	4	0501a8aa850bd2e347020abd1cac4d8075738189
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 EGFR AVPR1A DNER	1.36e-04	188	62	4	433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 EGFR DNER NOTCH2	1.36e-04	188	62	4	4544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 THRB PCLO SORL1	1.39e-04	189	62	4	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DNER LRBA LRP1B F11	1.39e-04	189	62	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 DNER LRBA LRP1B	1.39e-04	189	62	4	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 EGFR AVPR1A DNER	1.39e-04	189	62	4	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VEGFC MDN1 EGFR NOTCH2	1.42e-04	190	62	4	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VEGFC FRAS1 ADAMTS9 LRP1B	1.42e-04	190	62	4	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VEGFC MDN1 EGFR NOTCH2	1.42e-04	190	62	4	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 EGFR AVPR1A DNER	1.45e-04	191	62	4	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRAS1 EGFR AVPR1A DNER	1.45e-04	191	62	4	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VEGFC ADAMTS9 ITGA6 LRP1B	1.48e-04	192	62	4	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	human_hepatoblastoma-Tumor_cells-T8\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	THRB EGFR KLKB1 F11	1.48e-04	192	62	4	e785135262f4c9cc66c403bf362bb34643b212c5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 THRB PCLO LRBA	1.51e-04	193	62	4	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FBN2 PLXNC1 NOTCH2 SORL1	1.51e-04	193	62	4	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VEGFC FRAS1 EGFR ADAMTS9	1.51e-04	193	62	4	cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VEGFC ADAMTS9 ITGA6 LRP1B	1.51e-04	193	62	4	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VEGFC FRAS1 EGFR ADAMTS9	1.51e-04	193	62	4	e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VEGFC FRAS1 EGFR ADAMTS9	1.51e-04	193	62	4	6ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 PCLO LRBA LRP1B	1.51e-04	193	62	4	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	COPD-Endothelial-VE_Capillary_B\|COPD / Disease state, Lineage and Cell class	VEGFC EGFR ADAMTS9 ITGA6	1.54e-04	194	62	4	18b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCell	COPD-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	VEGFC EGFR ADAMTS9 ITGA6	1.54e-04	194	62	4	68705a6eca947c5b42b943d5224a7aef2a744007
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 PCLO LRBA LRP1B	1.57e-04	195	62	4	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP2R5A AVPR1A ABHD2 ITGA6	1.57e-04	195	62	4	f7d9adadd37209ce1a38e5d621607b9c9270fed8
ToppCell	PSB-critical-LOC-Epithelial-Secretory\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	THRB LPP NOTCH2 SORL1	1.66e-04	198	62	4	e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	CERK CDC42SE2 FAS SORL1	1.66e-04	198	62	4	6333e46cd1ccf5841ce15aea98a4b2f5e3ae4675
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Vein\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	VEGFC PPP2R5A ADAMTS9 ITGA6	1.69e-04	199	62	4	cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)--\|Striatum / BrainAtlas - Mouse McCarroll V32	AVPR1A GABRQ TECTA	1.69e-04	77	62	3	7bb18406d404c51ee938cc577c155dc51868ddb9
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)\|Striatum / BrainAtlas - Mouse McCarroll V32	AVPR1A GABRQ TECTA	1.69e-04	77	62	3	ac311740424ff75b478b3c19fa0fae93776eb54e
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Chodl_(Low-threshold_spiking_interneuron,_Npy+/Sst+)-\|Striatum / BrainAtlas - Mouse McCarroll V32	AVPR1A GABRQ TECTA	1.69e-04	77	62	3	9f2dbf922acb905d636427a766a217c0db9671d2
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / Treatment groups by lineage, cell group, cell type	VEGFC PPP2R5A ADAMTS9 ITGA6	1.73e-04	200	62	4	b036f5e22c95a3b14391785b6e91aa183b9bc9a8
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FRAS1 EGFR AVPR1A DNER	1.73e-04	200	62	4	d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FRAS1 EGFR AVPR1A DNER	1.73e-04	200	62	4	862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FRAS1 EGFR AVPR1A DNER	1.73e-04	200	62	4	a91345f268f13170c27309333603eb82400c9947
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	ZNF276 ABHD2 LPP ITGA6 FAS NOTCH2 SORL1	2.13e-07	155	62	7	6817_DN
Drug	nickel hydroxide	TRAF5 TRAF6 TNFRSF8 TONSL DNER GABRQ FAS	6.56e-06	259	62	7	CID000025500
Drug	Epirubicin	VEGFC THRB EGFR FAS	8.14e-06	47	62	4	ctd:D015251
Drug	2-vinyl benzaldehyde	TONSL DNER FAS KLKB1 F11	1.14e-05	108	62	5	CID000039391
Drug	estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	RCHY1 ABHD2 OASL ITGA6 FAS NOTCH2	1.38e-05	192	62	6	5955_UP
Drug	Sulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; HL60; HT_HG-U133A	VEGFC EGFR PCLO LPP GABRQ HABP2	1.55e-05	196	62	6	2560_UP
Disease	Diffuse Large B-Cell Lymphoma	TRAF5 FBXO11 FAS EP300 NOTCH2	1.11e-07	55	62	5	C0079744
Disease	breast carcinoma (is_implicated_in)	VEGFC THRB EGFR FBXO11	2.16e-07	25	62	4	DOID:3459 (is_implicated_in)
Disease	sunburn	MMS22L ADAM30 EXOC2 NOTCH2	5.08e-05	96	62	4	EFO_0003958
Disease	mosquito bite reaction size measurement	CDC42SE2 TNFRSF8 LPP FAS ZRANB3	8.47e-05	212	62	5	EFO_0008378
Disease	factor XI measurement	KLKB1 F11	1.21e-04	8	62	2	EFO_0004694
Disease	triacylglycerol 58:6 measurement	TRAF6 LRP1B	1.21e-04	8	62	2	EFO_0010440
Disease	Squamous cell carcinoma	EGFR FAS EP300 NOTCH2	1.37e-04	124	62	4	C0007137
Disease	type 1 diabetes mellitus	C6orf118 ADAM30 EXOC2 LRP1B NOTCH2	1.57e-04	242	62	5	MONDO_0005147
Disease	alopecia areata	PLXNC1 LPP EXOC2	1.61e-04	50	62	3	EFO_0004192
Disease	Bladder Neoplasm	EGFR FAS EP300 NOTCH2	2.19e-04	140	62	4	C0005695
Disease	Malignant neoplasm of urinary bladder	EGFR FAS EP300 NOTCH2	2.25e-04	141	62	4	C0005684
Disease	cryptorchidism (biomarker_via_orthology)	KDM5A FAS	2.36e-04	11	62	2	DOID:11383 (biomarker_via_orthology)
Disease	word reading	ZNF346 MMS22L SORL1	3.52e-04	65	62	3	EFO_0005300
Disease	breast carcinoma (is_marker_for)	EGFR FAS EP300	3.68e-04	66	62	3	DOID:3459 (is_marker_for)
Disease	hepatocellular carcinoma (is_marker_for)	VEGFC EGFR FBXO11 FAS LRP1B	4.30e-04	301	62	5	DOID:684 (is_marker_for)
Disease	autoimmune disease	PLXNC1 LPP FAM76B EXOC2	4.88e-04	173	62	4	EFO_0005140
Disease	Leukemia, Myelocytic, Acute	LPP FAS EP300 NOTCH2	4.88e-04	173	62	4	C0023467
Disease	mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement	FRAS1 CDC42SE2 ABHD2 ITGA6 FBXO11	6.34e-04	328	62	5	EFO_0008377, EFO_0008378
Disease	autoimmune thyroid disease, Hashimoto's thyroiditis, Graves disease	LPP FAM76B	6.50e-04	18	62	2	EFO_0003779, EFO_0004237, EFO_0006812
Disease	macula measurement	C6orf118 ADAMTS9 FAM76B SORL1	6.81e-04	189	62	4	EFO_0008375
Disease	glomerulonephritis (is_marker_for)	KLKB1 EP300	7.26e-04	19	62	2	DOID:2921 (is_marker_for)
Disease	alcohol use disorder (implicated_via_orthology)	EGFR KDM5A EP300 NOTCH2	7.65e-04	195	62	4	DOID:1574 (implicated_via_orthology)
Disease	Autism Spectrum Disorders	AVPR1A GABRQ USH2A	7.72e-04	85	62	3	C1510586
Disease	eosinophil percentage of leukocytes	PLXNC1 TNFRSF8 LPP FAM76B HABP2 EXOC2 NOTCH2	9.45e-04	746	62	7	EFO_0007991
Disease	asthma	THRB ADAMTS9 PLXNC1 TNFRSF8 TGFBRAP1 LPP LRP1B	9.82e-04	751	62	7	MONDO_0004979
Disease	eosinophil count	MED24 MDN1 PLXNC1 TNFRSF8 LPP FAM76B ITGA6 HABP2 EXOC2 NOTCH2	1.01e-03	1488	62	10	EFO_0004842
Disease	Disorder of eye	FRAS1 LRP5 CPLANE1 USH2A	1.04e-03	212	62	4	C0015397
Disease	Squamous cell carcinoma of esophagus	EGFR EP300 NOTCH2	1.07e-03	95	62	3	C0279626
Disease	partial thromboplastin time	KLKB1 F11	1.16e-03	24	62	2	EFO_0004310
Disease	Diabetes Mellitus, Non-Insulin-Dependent	EGFR ADAMTS9 FAS NOTCH2	1.22e-03	221	62	4	C0011860
Disease	non-Hodgkins lymphoma	VEGFC EXOC2	1.26e-03	25	62	2	EFO_0005952
Disease	neurotic disorder	MED24 MMS22L PCLO	1.27e-03	101	62	3	EFO_0004257
Disease	cancer	ZNF276 FBN2 FAM76B ITGA6 KLKB1	1.53e-03	400	62	5	MONDO_0004992
Disease	Hodgkins lymphoma, multiple myeloma, chronic lymphocytic leukemia	LPP EXOC2	1.59e-03	28	62	2	EFO_0000095, EFO_0000183, EFO_0001378
Disease	chronic obstructive pulmonary disease (biomarker_via_orthology)	EGFR FAS	1.59e-03	28	62	2	DOID:3083 (biomarker_via_orthology)
Disease	RS-10-hydroxywarfarin to RS-warfarin ratio measurement	FRAS1 C6orf118 TMEM74	1.62e-03	110	62	3	EFO_0803335
Disease	estradiol measurement	ZNF346 PLXNC1 FBXO11	1.62e-03	110	62	3	EFO_0004697
Disease	antipsychotic drug use measurement	C6orf118 THRB	1.70e-03	29	62	2	EFO_0007792
Disease	prostate cancer (is_implicated_in)	THRB EGFR FAS	1.94e-03	117	62	3	DOID:10283 (is_implicated_in)
Disease	chronic lymphocytic leukemia	LPP EXOC2 FAS	2.03e-03	119	62	3	EFO_0000095
Disease	intestinal cancer (implicated_via_orthology)	EGFR NOTCH2	2.07e-03	32	62	2	DOID:10155 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CQCRNANCSLPSCQK	EP300	1746	Q09472
SCCEEQNKVNCLQTR	AFM	191	P43652
QANQEKVLCCVSVCQ	ABHD2	221	P08910
NGQCVDKVNRFQCLC	NOTCH2	506	Q04721
AQACLRRCSKNQQPQ	MDN1	2951	Q9NU22
LQIAANQCCPECVLR	FRAS1	76	Q86XX4
VAQCFTAQCQPLFCN	FRAS1	186	Q86XX4
CPDDQFKCQNNRCIP	LRP1B	886	Q9NZR2
VNEKNLLSCCKNQCP	NFXL1	756	Q6ZNB6
GECPFNCNQKVKLRC	NFXL1	786	Q6ZNB6
CIVCCQSQNPNAYLN	MMS22L	1006	Q6ZRQ5
PEVVLNLFNCKNCAN	GABRQ	41	Q9UN88
SMKNCFQLLCNCQVP	LIPT1	6	Q9Y234
NCCRQGTVCLQIQME	ARRDC5	181	A6NEK1
FRCASGQCVLIKQQC	LRP5	1341	O75197
LCFNCCIAEQPQPKR	CDC42SE2	6	Q9NRR3
CQRIFQVNAPINCVC	MLST8	121	Q9BVC4
FNTCTECKNQVCNLC	PCLO	1076	Q9Y6V0
CQNKSQPNRTCTCSI	PLXNC1	546	O60486
SLPCQFEQCIVCSLQ	EXOC2	616	Q96KP1
CFTCIICNNKLRGQP	LPP	441	Q93052
LVCAVAVRNCLECQQ	LRBA	1446	P50851
QTCEQCKQQCAFDRK	FAM76B	101	Q5HYJ3
NCSVNVNCVNIRCPL	ITGA6	966	P23229
ENAVCAAQNCQRPCK	KDM5A	1606	P29375
IVAQRASQCLKQDCC	OASL	321	Q15646
NKCQKVQNTCKDNPC	HABP2	106	Q14520
NCQKLTKIICAQQCS	EGFR	206	P00533
CQKDRCCQSNCKLQP	ADAM30	421	Q9UKF2
TCRNVYNCELPQNCK	ADAMTS9	1726	Q9P2N4
RCIFKAIQCNDINPQ	CPLANE1	1716	Q9H799
CNTTDRNAICVNCIK	FBXO11	856	Q86XK2
PCRAGCFVCRQSKQQ	CERK	346	Q8TCT0
QELQKICTCSPQQFN	C6orf118	251	Q5T5N4
ACQKLCTNAVRCQFF	F11	316	P03951
ICQDTNQVLFKCCQG	KANSL2	326	Q9H9L4
ECQKRCTNNIRCQFF	KLKB1	136	P03952
QIQCRLPLQQCCVKG	KPRP	6	Q5T749
CSPRARQFQPQCQVC	CXorf38	66	Q8TB03
ECAQNPLLCAFRCMN	FBN2	2256	P35556
DACQRKPCQNNASCI	DNER	351	Q8NFT8
LRQNNSFLCLPCNCD	USH2A	836	O75445
CVSCCLQPNKQLLLE	SPRING1	131	Q9H741
CVKQENTCLRNQYRC	SORL1	1071	Q92673
NCDCTNFLLQECGKQ	MED24	356	O75448
QCLFQPVQCSNEKCR	TRAF5	131	O00463
EQQELFCQKLQQCCI	PPP2R5A	66	Q15172
PCQKQACEIQKCLQA	CMC4	6	P56277
CFRRNVIQCDPRQCK	TECTA	1451	O75443
KLCQICQNPFCEPVF	TGFBRAP1	816	Q8WUH2
DRNSCQCVCKNKLFP	VEGFC	311	P49767
RTQNTKCRCKPNFFC	FAS	121	P25445
APCFQKALSCAQQAQ	TONSL	411	Q96HA7
QNCPLANVICEYCNT	TRAF6	206	Q9Y4K3
CVIDKVTRNQCQECR	THRB	151	P10828
QNFCEKFCQCNPDCQ	EZH1	541	Q92800
NRFPGCRCKTQCNTK	EZH1	556	Q92800
AKPLQCEVCGFQCRQ	ZNF276	521	Q8N554
QQCPQRPTDCRKQCE	TNFRSF8	56	P28908
LQDCVQSFPCCQNMK	AVPR1A	356	P37288
NQCLFTNTQCKVCCA	ZNF346	66	Q9UL40
QCINCEKIQHAQQTC	RCHY1	61	Q96PM5
NQITAERKVCNCCSQ	TMEM74	91	Q96NL1
LCLRCQQPTCQTKQA	ZRANB3	911	Q5FWF4
FRCNINCDEDPKNCI	NAGA	36	P17050