Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERCC3 ANGEL2 CNOT7 ERCC6L2 DDX56 EXOG TOP1 AQR CNOT8 TDRD12

1.61e-046457610GO:0140640
GeneOntologyMolecularFunctionhelicase activity

ERCC3 ERCC6L2 DDX56 AQR TDRD12

3.42e-04158765GO:0004386
GeneOntologyMolecularFunction3'-5'-RNA exonuclease activity

ANGEL2 CNOT7 CNOT8

3.75e-0437763GO:0000175
GeneOntologyMolecularFunctionexonuclease activity

ANGEL2 CNOT7 EXOG CNOT8

4.20e-0492764GO:0004527
GeneOntologyMolecularFunctionRNA exonuclease activity, producing 5'-phosphomonoesters

ANGEL2 CNOT7 CNOT8

4.73e-0440763GO:0016896
GeneOntologyMolecularFunctionRNA exonuclease activity

ANGEL2 CNOT7 CNOT8

6.70e-0445763GO:0004532
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ANGEL2 CNOT7 DDX56 EXOG AQR CNOT8 TDRD12

1.04e-03417767GO:0140098
GeneOntologyMolecularFunctionpoly(A)-specific ribonuclease activity

CNOT7 CNOT8

1.09e-0313762GO:0004535
DomainCAF1

CNOT7 CNOT8

1.58e-045752PF04857
DomainRNase_CAF1

CNOT7 CNOT8

1.58e-045752IPR006941
DomainP-loop_NTPase

ERCC3 MYO1D GBP7 ABCA13 HS6ST2 ERCC6L2 DDX56 RAB3A AQR TDRD12

2.02e-038487510IPR027417
DomainGal_mutarotase_SF_dom

MAN2A1 MGAM2

2.08e-0317752IPR011013
DomainFCH

SRGAP3 SRGAP2

3.49e-0322752PF00611
DomainFCH

SRGAP3 SRGAP2

3.49e-0322752SM00055
DomainFCH_dom

SRGAP3 SRGAP2

3.81e-0323752IPR001060
DomainF_BAR

SRGAP3 SRGAP2

4.50e-0325752IPR031160
DomainF_BAR

SRGAP3 SRGAP2

4.50e-0325752PS51741
DomainMit_carrier

SLC25A21 SLC25A12

7.30e-0332752IPR002067
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GTF3C1 MYO1D RPN2 SYNE2 USP24 DOCK7 NUP133 DDX56 TOP1 AQR PPP6R3

2.04e-07653771122586326
Pubmed

A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

CACNA1B LRRC7 GRM5

8.68e-07977328130356
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

PPP2R2B SRGAP3 SYNE2 USP24 RAB3A TOP1 AQR STRIP1 PPP6R3

1.60e-0649877936634849
Pubmed

Interleukin-18 plays a dispensable role in murine and likely also human bone marrow failure.

IL18 IL18R1

4.84e-06277230316805
Pubmed

Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain.

IL18 IL18R1

4.84e-06277228373090
Pubmed

IL-18/IL-18R1 promotes circulating fibrocyte differentiation in the aging population.

IL18 IL18R1

4.84e-06277232193584
Pubmed

Postnatal changes of interleukin-18 receptor immunoreactivity in neurons of the retrosplenial cortex in wild-type and interleukin-18 knock out mice.

IL18 IL18R1

4.84e-06277229681594
Pubmed

Conservation of the deadenylase activity of proteins of the Caf1 family in human.

CNOT7 CNOT8

4.84e-06277215769875
Pubmed

Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infection.

IL18 IL18R1

4.84e-06277219223481
Pubmed

Evaluation of IL18 and IL18R1 polymorphisms: genetic susceptibility to knee osteoarthritis.

IL18 IL18R1

4.84e-06277222136483
Pubmed

Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization.

EEF1AKMT4-ECE2 ECE2

4.84e-06277211718899
Pubmed

Interleukin-18 and interleukin-18 receptor-α expression in allergic asthma.

IL18 IL18R1

4.84e-06277221965503
Pubmed

Lrrc7 mutant mice model developmental emotional dysregulation that can be alleviated by mGluR5 allosteric modulation.

LRRC7 GRM5

4.84e-06277231582721
Pubmed

Single Nucleotide Polymorphism of Interleukin-18 and Interleukin-18 Receptor and the Risk of Papillary Thyroid Cancer.

IL18 IL18R1

4.84e-06277226600055
Pubmed

The structure and binding mode of interleukin-18.

IL18 IL18R1

4.84e-06277214528293
Pubmed

Variola virus IL-18 binding protein interacts with three human IL-18 residues that are part of a binding site for human IL-18 receptor alpha subunit.

IL18 IL18R1

4.84e-06277216979683
Pubmed

[Expression of interleukin-18 and interleukin-18 receptor alpha chain of the peripheral white blood cells in immune thrombocytopenia].

IL18 IL18R1

4.84e-06277220627039
Pubmed

Increased expression of serum IL-18 and IL-18R in newly diagnosed type 2 diabetes mellitus.

IL18 IL18R1

4.84e-06277233103874
Pubmed

Common SNPs/haplotypes in IL18R1 and IL18 genes are associated with variations in humoral immunity to smallpox vaccination in Caucasians and African Americans.

IL18 IL18R1

4.84e-06277221742843
Pubmed

CNOT7 Outcompetes Its Paralog CNOT8 for Integration into The CCR4-NOT Complex.

CNOT7 CNOT8

4.84e-06277235248544
Pubmed

IL-18 is induced and IL-18 receptor alpha plays a critical role in the pathogenesis of cigarette smoke-induced pulmonary emphysema and inflammation.

IL18 IL18R1

4.84e-06277217237446
Pubmed

Inflammation-Dependent IL18 Signaling Restricts Hepatocellular Carcinoma Growth by Enhancing the Accumulation and Activity of Tumor-Infiltrating Lymphocytes.

IL18 IL18R1

4.84e-06277226893476
Pubmed

The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation.

CNOT7 CNOT8

4.84e-06277219605561
Pubmed

Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice.

IL18 IL18R1

4.84e-06277226656097
Pubmed

Protection of CD8+ T cells from activation-induced cell death by IL-18.

IL18 IL18R1

4.84e-06277217400610
Pubmed

The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.

IL18 IL18R1

4.84e-06277221715688
Pubmed

The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.

SRGAP3 SRGAP2

4.84e-06277223505444
Pubmed

Structural basis for the specific recognition of IL-18 by its alpha receptor.

IL18 IL18R1

4.84e-06277225261253
Pubmed

Analysis of the association of polymorphic loci rs917997 in IL18RAP gene and rs187238 in IL18 gene with the risk for non-Hodgkin's malignant lymphomas in Novosibirsk population.

IL18 IL18R1

4.84e-06277224909718
Pubmed

IL-18R-dependent and independent pathways account for IL-18-enhanced antitumor ability of CAR-T cells.

IL18 IL18R1

4.84e-06277231914650
Pubmed

IL18 and IL18R1 polymorphisms, lung CT and fibrosis: A longitudinal study in coal miners.

IL18 IL18R1

4.84e-06277216971411
Pubmed

Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor.

IL18 IL18R1

4.84e-06277217075045
Pubmed

[The role of interleukin-18 and interleukin-18 receptor in predominant Th1 immune response of patients with immune thrombocytopenia].

IL18 IL18R1

4.84e-06277219954659
Pubmed

Behavioral and genetic investigations of low exploratory behavior in Il18r1(-/-) mice: we can't always blame it on the targeted gene.

IL18 IL18R1

4.84e-06277220580925
Pubmed

Human dendritic cells express the IL-18R and are chemoattracted to IL-18.

IL18 IL18R1

4.84e-06277214662834
Pubmed

IL-18/IL-18R Signaling Is Dispensable for ILC Development But Constrains the Growth of ILCP/ILCs.

IL18 IL18R1

4.84e-06277235874724
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CACNA1B MYO1D ABCA13 DOCK7 RPA1 TDRD12

7.09e-0620877633230847
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

ERCC3 SLC25A12 GTF3C1 RPN2 NUP133 TOP1

7.69e-0621177617314511
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SRGAP3 SYNE2 DOCK7 PAK3 LRRC7 SRGAP2 EXOG GRM5 RPA1 RAB3A STRIP1

8.74e-06963771128671696
Pubmed

Purification and characterization of the human interleukin-18 receptor.

IL18 IL18R1

1.45e-0537729325300
Pubmed

Inflammasome-dependent and -independent IL-18 production mediates immunity to the ISCOMATRIX adjuvant.

IL18 IL18R1

1.45e-05377224610009
Pubmed

ACSL6-activated IL-18R1-NF-κB promotes IL-18-mediated tumor immune evasion and tumor progression.

IL18 IL18R1

1.45e-05377239292786
Pubmed

IL-18 and Subcapsular Lymph Node Macrophages are Essential for Enhanced B Cell Responses with TLR4 Agonist Adjuvants.

IL18 IL18R1

1.45e-05377227794001
Pubmed

Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance.

IL18 IL18R1

1.45e-05377216732281
Pubmed

Angiotensin II enhances interleukin-18 mediated inflammatory gene expression in vascular smooth muscle cells: a novel cross-talk in the pathogenesis of atherosclerosis.

IL18 IL18R1

1.45e-05377215860756
Pubmed

[Elevated IL-18, IL-18 binding protein and IL-18 receptor in eosinophil-enriched blood cells in patients with asthma].

IL18 IL18R1

1.45e-05377228395725
Pubmed

Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation.

IL18 IL18R1

1.45e-05377236482059
Pubmed

IL18-family Genes Polymorphism Is Associated with the Risk of Myocardial Infarction and IL18 Concentration in Patients with Coronary Artery Disease.

IL18 IL18R1

1.45e-05377233522333
Pubmed

The structural basis for receptor recognition of human interleukin-18.

IL18 IL18R1

1.45e-05377225500532
Pubmed

IL18 signaling promotes homing of mature Tregs into the thymus.

IL18 IL18R1

1.45e-05377232687059
Pubmed

The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs.

CNOT7 CNOT8

1.45e-05377227605379
Pubmed

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18.

IL18 IL18R1

1.45e-05377220624890
Pubmed

Over-expression of IL-18, ICE and IL-18 R in testicular tissue from sexually immature as compared to mature mice.

IL18 IL18R1

1.45e-05377218299270
Pubmed

CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells.

CNOT7 CNOT8

1.45e-05377220065043
Pubmed

The CCR4-NOT complex suppresses untimely translational activation of maternal mRNAs.

CNOT7 CNOT8

1.45e-05377237767629
Pubmed

Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.

SRGAP3 SRGAP2

1.45e-05377219137586
Pubmed

Expression of IL-18, IL-18 binding protein, and IL-18 receptor by normal and cancerous human ovarian tissues: possible implication of IL-18 in the pathogenesis of ovarian carcinoma.

IL18 IL18R1

1.45e-05377224963217
Pubmed

Genetic variation in IL18R1 and IL18 genes and Inteferon γ ELISPOT response to smallpox vaccination: an unexpected relationship.

IL18 IL18R1

1.45e-05377223901078
Pubmed

IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells.

IL18 IL18R1

1.45e-05377225780034
Pubmed

Eutopic endometrial interleukin-18 system mRNA and protein expression at the level of endometrial-myometrial interface in adenomyosis patients.

IL18 IL18R1

1.45e-05377219394601
Pubmed

The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module.

CNOT7 CNOT8

1.45e-05377225944446
Pubmed

Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R.

IL18 IL18R1

1.45e-05377228922563
Pubmed

Interleukin-18 mediates interleukin-1-induced cardiac dysfunction.

IL18 IL18R1

1.45e-05377224531812
Pubmed

Innate immune activation of CD4 T cells in salmonella-infected mice is dependent on IL-18.

IL18 IL18R1

1.45e-05377217475863
Pubmed

Lack of association between polymorphisms of the IL18R1 and IL18RAP genes and cardiovascular risk: the MORGAM Project.

IL18 IL18R1

1.45e-05377219473509
Pubmed

Frequent loss of BTG1 activity and impaired interactions with the Caf1 subunit of the Ccr4-Not deadenylase in non-Hodgkin lymphoma.

CNOT7 CNOT8

1.45e-05377233021411
Pubmed

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor.

IL18 IL18R1

1.45e-05377210227969
Pubmed

Genetic association of short sleep duration with hypertension incidence--a 6-year follow-up in the Korean genome and epidemiology study.

MYO1D LRRC7

1.45e-05377222322875
Pubmed

Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway.

CNOT7 CNOT8

2.89e-05477211136725
Pubmed

Identification of four families of yCCR4- and Mg2+-dependent endonuclease-related proteins in higher eukaryotes, and characterization of orthologs of yCCR4 with a conserved leucine-rich repeat essential for hCAF1/hPOP2 binding.

CNOT7 CNOT8

2.89e-05477211747467
Pubmed

Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation.

IL18 IL18R1

2.89e-05477216906165
Pubmed

Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice.

IL18 IL18R1

2.89e-05477230127003
Pubmed

IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells.

IL18 IL18R1

2.89e-05477210653850
Pubmed

Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease.

IL18 IL18R1

2.89e-05477216043644
Pubmed

DNA topoisomerase I and PC4 can interact with human TFIIIC to promote both accurate termination and transcription reinitiation by RNA polymerase III.

GTF3C1 TOP1

2.89e-0547729660958
Pubmed

Functional role played by the glycosylphosphatidylinositol anchor glycan of CD48 in interleukin-18-induced interferon-gamma production.

IL18 IL18R1

2.89e-05477215760905
Pubmed

Human carbon catabolite repressor protein (CCR4)-associative factor 1: cloning, expression and characterization of its interaction with the B-cell translocation protein BTG1.

CNOT7 CNOT8

2.89e-0547729820826
Pubmed

Effect of IL-18 on the release of IL-6 and its soluble receptors: sIL-6Ralpha and sgp130 by human neutrophils.

IL18 IL6ST

2.89e-05477212472176
Pubmed

Adoptive immunotherapy with transient anti-CD4 treatment enhances anti-tumor response by increasing IL-18Rαhi CD8+ T cells.

IL18 IL18R1

2.89e-05477234493727
Pubmed

Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent Mechanism.

IL18 IL6ST

2.89e-05477229282220
Pubmed

The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex.

CNOT7 CNOT8

2.89e-05477223236473
Pubmed

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.

IL18 IL18R1

2.89e-05477226099046
Pubmed

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.

IL18 IL18R1

2.89e-05477226638073
Pubmed

Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation.

CNOT7 CNOT8

2.89e-05477220595394
Pubmed

A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection.

IL18 IL18R1

2.89e-05477229847790
Pubmed

Role of the inflammasome-related cytokines Il-1 and Il-18 during infection with murine coronavirus.

IL18 IL18R1

2.89e-05477228895072
Pubmed

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.

IL18 IL18R1

4.82e-05577227668799
Pubmed

IL-18 induces PD-1-dependent immunosuppression in cancer.

IL18 IL18R1

4.82e-05577221724589
Pubmed

Interleukin-1F7B (IL-1H4/IL-1F7) is processed by caspase-1 and mature IL-1F7B binds to the IL-18 receptor but does not induce IFN-gamma production.

IL18 IL18R1

4.82e-05577212096920
Pubmed

Interleukin 18 (IL-18) in synergy with IL-2 induces lethal lung injury in mice: a potential role for cytokines, chemokines, and natural killer cells in the pathogenesis of interstitial pneumonia.

IL18 IL18R1

4.82e-05577211830478
Pubmed

Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase.

CNOT7 CNOT8

4.82e-05577221336257
Pubmed

Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.

IL18 IL18R1

4.82e-05577231923399
Pubmed

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.

CNOT7 CNOT8

4.82e-05577222977175
Pubmed

Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition.

CNOT7 CNOT8

4.82e-05577235390160
Pubmed

Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.

IL18 IL18R1

4.82e-05577237993714
Pubmed

Human transcription factor protein interaction networks.

GTF3C1 MYO1D RPN2 SYNE2 CNOT7 CDK11A DDX56 TAF2 RPA1 TOP1 CNOT8 PPP6R3

6.86e-051429771235140242
Pubmed

hCAF1, a new regulator of PRMT1-dependent arginine methylation.

CNOT7 CNOT8

7.22e-05677217264152
Pubmed

IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock.

IL18 IL18R1

7.22e-05677234798063
Pubmed

A role for IL-18 in protective immunity against Mycobacterium tuberculosis.

IL18 IL18R1

7.22e-05677219950174
Pubmed

TNFalpha and TGF-beta1 influence IL-18-induced IFNgamma production through regulation of IL-18 receptor and T-bet expression.

IL18 IL18R1

7.22e-05677219879772
Cytoband20q12-q13.1

RPN2 TOP1

1.24e-041077220q12-q13.1
GeneFamilyCCR4-NOT transcription complex

CNOT7 CNOT8

5.27e-04115721023
CoexpressionMEK_UP.V1_DN

NDUFAF1 TFPI2 ANGEL2 TAF2 RMC1 AQR

2.33e-05194776M2724
CoexpressionGSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_DN

MAN2A1 ERCC6L2 NUP133 IL6ST STRIP1 PPP6R3

2.47e-05196776M8675
CoexpressionGSE27786_LSK_VS_LIN_NEG_CELL_DN

MAN2A1 MYO1D USP24 ITGA1 TMC5 IL6ST

2.77e-05200776M4742
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

PPP2R2B SRGAP3 HIKESHI SYNE2 PAK3 RAB3A MGAT4C

5.71e-082007772a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

PAK3 ITGA1 GRM5 MGAT4C BICC1 SERPINA7

6.84e-07179776e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SUSD1 ABCA13 SRGAP3 SYNE2 GRM5 BICC1

9.39e-07189776904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

9.99e-071917762a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

9.99e-0719177646c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

9.99e-07191776995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

9.99e-07191776a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

9.99e-071917762d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

9.99e-07191776e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

1.09e-0619477643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

1.13e-0619577634e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

1.31e-06200776f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

1.31e-06200776d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57 TMC5

1.31e-06200776cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellCiliated_cells-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

8.33e-061597750c65ae6140abd48c79b04758a6217709ddd15385
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

1.29e-05174775b8d1c556290d188f56aeefc17f03119686945fe7
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

1.29e-0517477500cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

1.40e-05177775c38138fb5ad9766c2d240811210c854338cd612e
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PPP2R2B IL18 ATP6V0A4 IL18R1 BICC1

1.44e-051787751e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNE2 GRM5 MGAT4C BICC1 SERPINA7

1.44e-05178775544379f5a6145429762258d426b876bb36c112f5
ToppCellASK454-Epithelial-Ciliated|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

1.48e-05179775f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Ciliated|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

1.56e-051817758eed9d46d924b16f6dd1a025ff612244b02b4391
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO4 ENAM GUCA1A SYNE2 ATP6V0A4

1.69e-05184775a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO4 ENAM GUCA1A SYNE2 ATP6V0A4

1.69e-0518477539c230d32e4259bc784e0edfd9e2884c96898564
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANO4 ENAM GUCA1A SYNE2 ATP6V0A4

1.69e-051847752a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

1.73e-051857754fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B PPP2R2B RAB3A MGAT4C ECE2

1.73e-05185775110d5f02759c8235b14aea524ea47199696094ea
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP126 CATSPERD AKAP14 CFAP57 BICC1

1.82e-051877756fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 SUSD1 SRGAP3 ATP6V0A4 DOCK7

1.82e-051877752d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D ABCA13 SRGAP3 GRM5 BICC1

1.87e-0518877563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

1.97e-0519077517829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-051917757b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-051917759f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-0519177528caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-051917755129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-0519177515b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class （2021.01.30）

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775b78547dae8328244a47c83346447bdd787efbcae
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class （2021.01.30）

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.02e-05191775cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-IPC_like-IPCs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

PPP2R2B SYNE2 RAB3A CRHR2 BICC1

2.07e-05192775bd91bf0ceeac49dc5a18aa2e401244db0ca596ae
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-IPC_like|6_mon / Sample Type, Dataset, Time_group, and Cell type.

PPP2R2B SYNE2 RAB3A CRHR2 BICC1

2.07e-0519277518fbf485ad762ba7a9ac3e19bad136b0cf3af3c5
ToppCellmulticiliated|World / shred by cell class for turbinate

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.07e-051927750f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.12e-05193775c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP126 ABCA13 AKAP14 CFAP57 TMC5

2.12e-05193775e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 TFPI2 SYNE2 GRM5 BICC1

2.12e-051937750f2167eef8203a5659c8c72e4e77646003d64797
ToppCellLAM-Epithelial-AirwayEpi|Epithelial / Condition, Lineage and Cell class

CFAP126 CATSPERD SRGAP3 AKAP14 CFAP57

2.12e-05193775f2672d2c495ee12c3b7d132452bde581fa5a7856
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.12e-05193775a0baa8be6f590b2031fede22be588715ae458e93
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.17e-051947755aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.17e-05194775b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP126 CATSPERD ABCA13 CFAP57 TMC5

2.23e-05195775649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.23e-05195775cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell18-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.23e-051957753441381759cd00d125752401dc99b78be1c78f88
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP126 CATSPERD ABCA13 CFAP57 TMC5

2.23e-05195775129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP126 CATSPERD ABCA13 CFAP57 TMC5

2.23e-051957753e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.23e-051957759651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.23e-0519577507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.28e-05196775686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.28e-0519677567aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.28e-05196775ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.28e-051967751cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.28e-0519677569f5081e06d84ec1d9695762df801a9d0df1984b
ToppCellSevere_COVID-19-T/NK-NK|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

PPP2R2B SRGAP3 HS6ST2 SYNE2 ITGA1

2.34e-05197775cc20162892b59e48653981f91fc9a0c27064444d
ToppCellwk_20-22-Epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.34e-05197775468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCelldistal-3-Epithelial-Proximal_Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.34e-0519777515b4d1203943ce90a7083178d4a4284d9b323071
ToppCellwk_20-22-Epithelial-Proximal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.40e-0519877516c54b884500066ade05a406915f9569ca8abdfc
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-051997751ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.46e-05199775b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-051997751df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-0519977581115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-0519977574087b4b5e567310fc4ac58fb267ff651a180680
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-0519977500b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-05199775ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-0519977591308b255783ad4029e5575028c18d7550832c51
ToppCelldistal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.46e-051997757e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCelldistal-Epithelial-Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.46e-051997756ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CFAP126 CATSPERD ABCA13 AKAP14 TMC5

2.46e-0519977572689bda7476930887ae007682fcab27f956f050
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.52e-05200775f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.52e-052007756a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellBiopsy_IPF-Epithelial-Differentiating_Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.52e-052007758dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCellmild-MAIT|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PPP2R2B GTF3C1 MYO1D SYNE2 IL18R1

2.52e-052007751e3ef15ce48b9a19a6ac3e08ea0234a9376e6596
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.52e-052007757cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellBiopsy_IPF|World / Sample group, Lineage and Cell type

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.52e-052007754de8c4789fb64250cb1dca94c108d39ab119bab4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.52e-05200775ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.52e-05200775a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP126 CATSPERD ABCA13 AKAP14 CFAP57

2.52e-05200775918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP126 CATSPERD AKAP14 CFAP57 TMC5

2.52e-052007758441e289377215a6877640946fe3f6de1f456502
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

PPP2R2B AKAP14 PPEF1 RAB3A

1.08e-04142774435f39976841438690fcbf85bfa8e7f5b9e43916
ToppCellcritical-Lymphoid-NKT|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP126 ABCA13 ATP6V0A4 AKAP14

1.11e-04143774dca035bfbfd1665c04076c43da8bc18a1502b9de
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GDF10 MGAT4C CRHR2 ECE2

1.26e-041487744d43efee96a6493abd78e9ca41aab73db0c80626
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ANO4 CFAP126 CATSPERD BICC1

1.30e-041497746399c5a2f06d79f020dece252526f1c0c110d569
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IL18 SUSD1 SRGAP3 ATP6V0A4

1.33e-0415077487968ce885a4959616f0321f58517fe8029ba1b1
ToppCellVE-CD8-memory_CD4|VE / Condition, Cell_class and T cell subcluster

GBP7 SYNE2 TAF2 GDF10

1.40e-041527749401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal|GW08 / Sample Type, Dataset, Time_group, and Cell type.

PPP2R2B HIKESHI RAB3A

1.46e-045977374590437b1d9a2a8fe56d79b2e66803528b81298
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1B ERCC3 CFAP57 TDRD12

1.58e-041577744766f7d545bf2d775390589460677519cb92f4d5
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1B SV2C GRM5 MGAT4C

1.66e-041597745335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
DrugN-carbamoylputrescine

AMD1 SLC25A21 AGA

1.90e-068753CID000000502
Drugaminopropylcadaverine

AMD1 SLC25A21 AGA

9.59e-0613753CID000065523
Diseaselipid measurement, intermediate density lipoprotein measurement

DOCK7 DDX56 ITGA1 TOP1

1.02e-0496744EFO_0004529, EFO_0008595
Diseaseheart disease (implicated_via_orthology)

IL18 CNOT7 CNOT8

1.20e-0438743DOID:114 (implicated_via_orthology)
Diseaseskin microbiome measurement

ANO4 SRGAP3 SRGAP2

1.30e-0439743EFO_0801228
Diseasetotal cholesterol measurement, low density lipoprotein cholesterol measurement

DOCK7 DDX56 ITGA1 TOP1

1.97e-04114744EFO_0004574, EFO_0004611
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

DOCK7 DDX56 ITGA1 TOP1

2.40e-04120744EFO_0004611, EFO_0004639
Diseaseapolipoprotein B measurement

UGT1A5 SYNE2 USP24 DOCK7 SV2C DDX56 ITGA1 TOP1

2.55e-04663748EFO_0004615
Diseasecholesteryl ester measurement, low density lipoprotein cholesterol measurement

DOCK7 DDX56 ITGA1 TOP1

2.89e-04126744EFO_0004611, EFO_0010351
Diseasefree cholesterol measurement, low density lipoprotein cholesterol measurement

USP24 DDX56 ITGA1 TOP1

3.98e-04137744EFO_0004611, EFO_0008591
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

SYNE2 USP24 DOCK7 DDX56 ITGA1

5.38e-04264745EFO_0008317, EFO_0020944
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

DOCK7 DTNBP1

6.38e-0415742DOID:2223 (implicated_via_orthology)
Diseaseschizophrenia (implicated_via_orthology)

SRGAP3 DTNBP1 GRM5

6.75e-0468743DOID:5419 (implicated_via_orthology)
DiseaseS-adenosylhomocysteine measurement

ANO4 CACNA1B

8.24e-0417742EFO_0010531
DiseaseRheumatoid Arthritis

IL18 SLC25A12 TFPI2 IL6ST

9.75e-04174744C0003873
Diseasebrain age measurement

EEF1AKMT4-ECE2 ECE2

1.14e-0320742EFO_0010602
Diseasereticulocyte count

EEF1AKMT4-ECE2 SLC25A21 MYO1D SUSD1 SYNE2 SV2C ITGA1 TAF2 CNOT8

1.19e-031045749EFO_0007986
Diseaseserum iron measurement

SRGAP3 SRGAP2 TMC5

1.33e-0386743EFO_0006332
Diseaseintermediate density lipoprotein measurement

DOCK7 DDX56 ITGA1

1.38e-0387743EFO_0008595
Diseaselung disease (is_marker_for)

IL18 IL18R1

1.39e-0322742DOID:850 (is_marker_for)
Diseasesleep duration, low density lipoprotein cholesterol measurement

USP24 DOCK7 DDX56

1.57e-0391743EFO_0004611, EFO_0005271
DiseaseSchizophrenia

CACNA1B IL18 ABCA13 SRGAP3 AGA DTNBP1 GRM5 IL18R1

1.64e-03883748C0036341
Diseasephospholipid measurement, intermediate density lipoprotein measurement

DDX56 ITGA1 TOP1

2.00e-0399743EFO_0004639, EFO_0008595
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

DOCK7 DDX56 ITGA1 TOP1

2.12e-03215744EFO_0008317, EFO_0008591
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

SYNE2 USP24 DOCK7 ITGA1

2.38e-03222744EFO_0008317, EFO_0020943
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

DOCK7 DDX56 ITGA1 TOP1

2.50e-03225744EFO_0008317, EFO_0010351

Protein segments in the cluster

PeptideGeneStartEntry
QKNLTDAKYSFMESF

AKAP14

176

Q86UN6
GSYNNFFRMFDRNTK

PPP2R2B

356

Q00005
YLGKQVFFTMDNFET

CATSPERD

66

Q86XM0
RISLFQYMSQFFNSS

ABCA13

1076

Q86UQ4
QYMSQFFNSSVEDLL

ABCA13

1081

Q86UQ4
SVKFFDTLYSIMQQS

ABCA13

2551

Q86UQ4
NMAFQKYSNMEQSLF

AQR

1106

O60306
MFLFQFVNLNSSTFY

ANO4

596

Q32M45
SENKFDFSVMSYNIL

ANGEL2

161

Q5VTE6
SSYVNMQAFDYEQKK

BICC1

721

Q9H694
FDFYKQNKTTRDQMQ

CACNA1B

1861

Q00975
QKESSDQNFDYMFKI

RAB3A

11

P20336
YTNMNVFENYEASKA

MGAT4C

346

Q9UBM8
QRYMTQFADQNFSDF

NUP133

886

Q8WUM0
NSYKSLVDSFRMIFQ

SLC25A21

51

Q9BQT8
YDSKETVNNQKYMSF

PAK3

141

O75914
NDTGSYFFQMKNYTQ

IL18R1

91

Q13478
KMFFETNENKDTTYQ

nan

271

O00370
ANFNEAKYIAFTMYT

GRM5

766

P41594
NYQQLFDYMNSQSKF

MAN2A1

441

Q16706
SFTYDNRQFMETNFK

MGAM2

1766

Q2M2H8
ASMTKKVYQFDQSFN

LRRC7

1021

Q96NW7
NNFDFQVQKFISMAF

CFAP57

101

Q96MR6
YQAFLMSATFNEDVQ

DDX56

191

Q9NY93
QKAVYFFNLTSMQDS

GDF10

111

P55107
ISEDSFFQNMLNLYN

ECE2

566

P0DPD6
QKFFEEAFQQDMEQY

DTNBP1

196

Q96EV8
SQIMFIYFNSFLQSF

CRHR2

336

Q13324
VFMEYSFKDKSQEFQ

GBP7

366

Q8N8V2
NNKFSSKAMAETFYL

EXOG

146

Q9Y2C4
FKILFQFNTSYLMEN

ITGA1

901

P56199
NKQFTAVKNDYEMTF

RPA1

266

P27694
YEISEDSFFQNMLNL

EEF1AKMT4-ECE2

636

P0DPD8
DSFFQNMLNLYNFSA

EEF1AKMT4-ECE2

641

P0DPD8
QFNFKFNLTEDMYAQ

CNOT7

96

Q9UIV1
DSFTQFTQKMLDNFY

HIKESHI

136

Q53FT3
FTQKMLDNFYNFASS

HIKESHI

141

Q53FT3
FNSKDQMYSDGNFTD

IL6ST

676

P40189
ISENFYFDLNSEQMK

DOCK7

296

Q96N67
DTDFFQRTNQMYSYF

NDUFAF1

226

Q9Y375
QSAMFNDYNFVFTSF

AMD1

311

P17707
AFYEMSLQAFNIFSQ

IFNK

86

Q9P0W0
SDQGFDLMNKFLTYF

CDK11A

681

Q9UQ88
MATNYSANQYEKAFS

CFAP126

1

Q5VTH2
SASQYVEQMFETFDF

GUCA1A

51

P43080
STFTQFSFMVYNSEK

AGA

321

P20933
KTFNMNFISPFTQYN

HS6ST2

446

Q96MM7
QFNFKFNLTEDMYSQ

CNOT8

96

Q9UFF9
SSKSEEMMRYNQFNF

ENAM

51

Q9NRM1
NAFFYSLVSQDTQEM

ERCC3

656

P19447
QFNAFKFLRSMSSVY

CUZD1

481

Q86UP6
RKQFEEMASYFNSSS

ERCC6L2

1236

Q5T890
DNKMQFESSSYEGYF

IL18

146

Q14116
QMQLSTFFSFMLENY

PPEF1

56

O14829
DKYANFTINFTMENQ

SV2C

476

Q496J9
FKKYNSLLSFMESFN

SYNE2

326

Q8WXH0
YQKFRNQFLSFSMYQ

TMEM120A

216

Q9BXJ8
NQFLSFSMYQSFVQF

TMEM120A

221

Q9BXJ8
TSEIFDMYQQYAAFK

MTRF1L

146

Q9UGC7
VKTNNFMSFQSYFLQ

TAF2

736

Q6P1X5
DYQKLNSAMNDFYNS

TDRD12

31

Q587J7
FFNQNIMSYITAKNS

STRIP1

616

Q5VSL9
FSYFNAFNSLLNNME

SLC25A12

216

O75746
QKFQEYEQCDMSFSL

ZNF177

201

Q13360
NQQETEMFYFTKFKE

SRGAP3

431

O43295
KQTEDNMLFYTIFRF

RMC1

601

Q96DM3
VFELNFMNVKFSSGY

RPN2

331

P04844
YQKEFAQEMTFNISS

SUSD1

531

Q6UWL2
ANQQETEQFYFTKMK

SRGAP2

441

O75044
KMSSINADFAFNLYR

SERPINA7

41

P05543
KYMSSFLFNLNNDFV

EZH1

661

Q92800
NMYIKEENFFTLTTY

UGT1A5

66

P35504
LFMFTYKSTQFNVEG

SLC35C2

151

Q9NQQ7
FINMFLFNYSDSSNA

ATP6V0A4

616

Q9HBG4
SYEITMNGFNLFKTF

USP24

781

Q9UPU5
FSLLFSMAKYFRNNF

TMC5

541

Q6UXY8
EKYFFNLSSMTCEKF

TFPI2

111

P48307
DSQMKSYQSFQTFRL

GTF3C1

1441

Q12789
FSDYQMQQMTSNFID

PPP6R3

546

Q5H9R7
EMFFKEFNQYLTSAL

TTL

261

Q8NG68
DFTQMSQYFKAQTEA

TOP1

301

P11387
VQYNNSYFSDVMTLK

ELFN2

326

Q5R3F8
TLFQDFKRLMYNSSN

MYO1D

526

O94832