Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	CXCR3 OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P GPR84 TAAR2 GPR87 VN1R17P OR2B3 OR8U3 F2RL1 ADGRG4 OR13J1 PTH2R CRHR2 TAAR6 OR8G1 OR52E2 OR1F1 FZD8 ADGRG7 ADORA3 OR51D1 TAS2R8 P2RY4 OR2A4 OR52H1 ADGRE5 GPR132 OR4F15	1.78e-18	884	129	35	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	CXCR3 OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 DNER OR1F12P GPR84 TAAR2 GPR87 VN1R17P OR2B3 OR8U3 F2RL1 ADGRG4 OR13J1 PTH2R CRHR2 TAAR6 OR8G1 OR52E2 OR1F1 FZD8 ADGRG7 ADORA3 OR51D1 TAS2R8 P2RY4 OR2A4 OR52H1 ADGRE5 GPR132 OR4F15	1.27e-13	1353	129	36	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	3.56e-10	431	129	18	GO:0004984
GeneOntologyMolecularFunction	glycogen synthase activity, transferring glucose-1-phosphate	GYS1 GYS2	4.14e-05	2	129	2	GO:0061547
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	B3GNT9 GALNT7 GYS1 UGT2A3 GYS2 UGT2A1 XXYLT1	6.19e-05	153	129	7	GO:0008194
GeneOntologyMolecularFunction	alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity	GYS1 GYS2	1.24e-04	3	129	2	GO:0004373
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	CXCR3 OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P GPR84 TAAR2 ZDHHC7 GPR87 VN1R17P OR2B3 OR8U3 F2RL1 ADCY1 ADGRG4 OR13J1 PTH2R CRHR2 TAAR6 OR8G1 OR52E2 OR1F1 FZD8 ADGRG7 ADORA3 OR51D1 TAS2R8 P2RY4 OR2A4 OR52H1 AKAP13 ADGRE5 GPR132 HTT OR4F15	8.05e-16	1395	130	39	GO:0007186
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P VN1R17P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 TAS2R8 OR2A4 OR52H1 UGT2A1 OR4F15	3.21e-11	547	130	21	GO:0007606
GeneOntologyBiologicalProcess	sensory perception of smell	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 UGT2A1 OR4F15	1.07e-10	465	130	19	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 RYR2 OR8G1 OR52E2 OR1F1 OR51D1 TAS2R8 OR2A4 OR52H1 OR4F15	1.10e-10	524	130	20	GO:0009593
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 TAS2R8 OR2A4 OR52H1 OR4F15	2.17e-10	485	130	19	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	2.52e-10	432	130	18	GO:0050911
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 TAS2R8 OR2A4 OR52H1 GJA10 OR4F15	6.89e-10	582	130	20	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 RYR2 OR8G1 OR52E2 OR1F1 OR51D1 TAS2R8 OR2A4 OR52H1 GJA10 OR4F15	4.85e-09	722	130	21	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P VN1R17P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 TAS2R8 LOXHD1 OR2A4 OR52H1 UGT2A1 GJA10 OR4F15	2.28e-07	1072	130	23	GO:0007600
GeneOntologyBiologicalProcess	atrial cardiac muscle cell to AV node cell communication	RYR2 NUP155 SCN5A	2.20e-04	19	130	3	GO:0086066
GeneOntologyBiologicalProcess	atrial cardiac muscle cell to AV node cell signaling	RYR2 NUP155 SCN5A	2.20e-04	19	130	3	GO:0086026
GeneOntologyBiologicalProcess	atrial cardiac muscle cell action potential	RYR2 NUP155 SCN5A	2.20e-04	19	130	3	GO:0086014
MousePheno	atrial fibrillation	RYR2 NUP155 SCN5A	2.52e-05	10	85	3	MP:0008543
Domain	G_PROTEIN_RECEP_F1_2	CXCR3 OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 OR1F12P GPR84 TAAR2 GPR87 OR2B3 OR8U3 F2RL1 OR13J1 TAAR6 OR8G1 OR52E2 OR1F1 ADORA3 OR51D1 TAS2R8 P2RY4 OR2A4 OR52H1 GPR132 OR4F15	1.54e-12	691	130	26	PS50262
Domain	GPCR_Rhodpsn	CXCR3 OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 OR1F12P GPR84 TAAR2 GPR87 OR2B3 OR8U3 F2RL1 OR13J1 TAAR6 OR8G1 OR52E2 OR1F1 ADORA3 OR51D1 TAS2R8 P2RY4 OR2A4 OR52H1 GPR132 OR4F15	1.59e-12	692	130	26	IPR000276
Domain	GPCR_Rhodpsn_7TM	CXCR3 OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 GPR84 TAAR2 GPR87 OR2B3 OR8U3 F2RL1 OR13J1 TAAR6 OR8G1 OR52E2 OR1F1 ADORA3 OR51D1 TAS2R8 P2RY4 OR2A4 OR52H1 GPR132 OR4F15	5.29e-12	670	130	25	IPR017452
Domain	7tm_1	CXCR3 OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 OR1F12P GPR84 TAAR2 GPR87 OR2B3 OR8U3 F2RL1 OR13J1 TAAR6 OR8G1 OR52E2 OR1F1 ADORA3 OR51D1 P2RY4 OR2A4 OR52H1 GPR132 OR4F15	6.63e-12	677	130	25	PF00001
Domain	G_PROTEIN_RECEP_F1_1	CXCR3 OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 OR1F12P GPR84 TAAR2 GPR87 OR2B3 OR8U3 F2RL1 OR13J1 TAAR6 OR8G1 OR52E2 OR1F1 ADORA3 OR51D1 P2RY4 OR2A4 OR52H1 GPR132 OR4F15	8.55e-12	685	130	25	PS00237
Domain	Olfact_rcpt	OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	1.49e-08	393	130	16	IPR000725
Domain	Pecanex_C	PCNX3 PCNX2 PCNX1	1.31e-06	4	130	3	PF05041
Domain	Pecanex	PCNX3 PCNX2 PCNX1	1.31e-06	4	130	3	IPR007735
Domain	GPCR_2_secretin-like	ADGRG4 PTH2R CRHR2 FZD8 ADGRG7 ADGRE5	3.73e-06	60	130	6	IPR000832
Domain	GPCR_2-like	ADGRG4 PTH2R CRHR2 FZD8 ADGRG7 ADGRE5	3.73e-06	60	130	6	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRG4 PTH2R CRHR2 FZD8 ADGRG7 ADGRE5	4.11e-06	61	130	6	PS50261
Domain	G_PROTEIN_RECEP_F2_2	ADGRG4 PTH2R CRHR2 ADGRG7 ADGRE5	2.49e-05	50	130	5	PS00650
Domain	7tm_2	ADGRG4 PTH2R CRHR2 ADGRG7 ADGRE5	2.49e-05	50	130	5	PF00002
Domain	Glycogen_synth	GYS1 GYS2	4.81e-05	2	130	2	IPR008631
Domain	Glycogen_syn	GYS1 GYS2	4.81e-05	2	130	2	PF05693
Domain	GPCR_2_secretin-like_CS	ADGRG4 PTH2R CRHR2 ADGRE5	8.84e-05	34	130	4	IPR017983
Domain	TAAR_fam	TAAR2 TAAR6	9.87e-04	7	130	2	IPR009132
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 LHX2 OR51D1 OR2A4 OR52H1 OR4F15	5.99e-11	417	98	19	M4072
Pathway	WP_GPCRS_OTHER	OR7E24 GPR84 VN1R17P PTH2R OR8G1 OR1F1 ADORA3 OR2A4 ADGRE5 GPR132	1.14e-09	96	98	10	MM15939
Pathway	REACTOME_SENSORY_PERCEPTION	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 LHX2 OR51D1 TAS2R8 OR2A4 OR52H1 OR4F15	1.14e-08	636	98	20	M41834
Pathway	WP_GPCRS_OTHER	CXCR3 OR7E24 GPR84 TAAR2 OR8G1 OR1F1 ADORA3 OR2A4 GPR132	1.55e-08	93	98	9	M39629
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR7E24 OR4N2 OR4N4 OR5AS1 OR2G2 OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	7.10e-08	389	98	15	M14091
Pathway	WP_GPCRS_ODORANT	OR7E24 GPR84 TAAR2 GPR87 VN1R17P ADGRG4 TAAR6 ADGRG7 OR2A4	1.42e-06	157	98	9	MM15872
Pathway	REACTOME_SIGNALING_BY_GPCR	CXCR3 GPR84 TAAR2 F2RL1 ADCY1 PTH2R CRHR2 TAAR6 FZD8 ADORA3 TAS2R8 ARHGEF33 P2RY4 AKAP13 ADGRE5 GPR132	2.50e-05	702	98	16	M746
Pathway	REACTOME_GPCR_LIGAND_BINDING	CXCR3 TAAR2 F2RL1 PTH2R CRHR2 TAAR6 FZD8 ADORA3 TAS2R8 P2RY4 ADGRE5 GPR132	8.57e-05	463	98	12	M507
Pathway	WP_DISORDERS_OF_GALACTOSE_METABOLISM	SLC2A2 GYS1 GYS2	8.86e-05	13	98	3	M45545
Pathway	WP_GPCRS_NONODORANT	CXCR3 F2RL1 PTH2R CRHR2 FZD8 ADORA3 P2RY4 ADGRE5 GPR132	9.64e-05	266	98	9	MM15843
Pathway	REACTOME_SIGNALING_BY_GPCR	CXCR3 GPR84 TAAR2 F2RL1 ADCY1 PTH2R CRHR2 TAAR6 ADORA3 ARHGEF33 P2RY4 AKAP13 ADGRE5 GPR132	1.45e-04	646	98	14	MM14962
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	CXCR3 GPR87 F2RL1 OR13J1 OR8G1 ADORA3 P2RY4	3.13e-04	186	98	7	MM15994
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	CXCR3 GPR87 OR2B3 F2RL1 OR1F1 ADORA3 P2RY4 OR2A4	4.52e-04	260	98	8	M39397
Pathway	KEGG_STARCH_AND_SUCROSE_METABOLISM	GYS1 UGT2A3 GYS2 UGT2A1	4.60e-04	52	98	4	M14171
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	PTH2R CRHR2 ADGRE5	5.93e-04	24	98	3	MM15992
Pathway	WP_GPCRS_CLASS_B_SECRETINLIKE	PTH2R CRHR2 ADGRE5	5.93e-04	24	98	3	M39643
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_BIOSYNTHESIS	GYS1 GYS2	7.05e-04	6	98	2	M47620
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	GPR84 TAAR2 ADCY1 PTH2R CRHR2 TAAR6	7.85e-04	157	98	6	M4904
Pathway	REACTOME_GPCR_LIGAND_BINDING	CXCR3 TAAR2 F2RL1 PTH2R CRHR2 TAAR6 ADORA3 P2RY4 ADGRE5 GPR132	8.02e-04	430	98	10	MM15160
Pubmed	The human olfactory receptor gene family.	OR5AC1 OR7E24 OR4N2 OR4N4 OR11H7 OR5AS1 OR2G2 OR1F12P OR2B3 OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	4.24e-12	541	135	18	14983052
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5AC1 OR7E24 OR4N2 OR11H7 OR5AS1 OR1F12P OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	5.59e-12	340	135	15	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5AC1 OR7E24 OR4N2 OR11H7 OR5AS1 OR1F12P OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	5.59e-12	340	135	15	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5AC1 OR7E24 OR4N2 OR11H7 OR5AS1 OR1F12P OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	6.33e-12	343	135	15	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5AC1 OR7E24 OR4N2 OR11H7 OR5AS1 OR1F12P OR8U3 OR13J1 OR8G1 OR52E2 OR1F1 OR51D1 OR2A4 OR52H1 OR4F15	7.16e-12	346	135	15	14611657
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	CXCR3 TAAR2 PTH2R CRHR2 TAAR6 ADORA3 P2RY4	1.39e-05	200	135	7	18240029
Pubmed	Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex.	ADCY1 PRKCZ	1.50e-05	2	135	2	21127255
Pubmed	Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.	RYR2 SCN5A	1.50e-05	2	135	2	23723061
Pubmed	A knock-in mouse model of N-terminal R420W mutation of cardiac ryanodine receptor exhibits arrhythmogenesis with abnormal calcium dynamics in cardiomyocytes.	RC3H1 RYR2	1.50e-05	2	135	2	25193700
Pubmed	Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions.	GJA8 GJA10	1.50e-05	2	135	2	25823610
Pubmed	Genetic analysis in post-mortem samples with micro-ischemic alterations.	RYR2 SCN5A	1.50e-05	2	135	2	28086167
Pubmed	Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.	RYR2 HTT	1.50e-05	2	135	2	32897880
Pubmed	Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.	RYR2 SCN5A	1.50e-05	2	135	2	26289036
Pubmed	Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.	BRWD3 WDR87 BRWD1	2.02e-05	14	135	3	28878358
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR7E24 OR11H7 OR2B3 OR13J1 OR8G1 OR1F1 OR4F15	2.50e-05	219	135	7	12213199
Pubmed	Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids.	SLC2A7 SLC2A2	4.48e-05	3	135	2	29548810
Pubmed	P2Y4 Nucleotide Receptor in Neuronal Precursors Induces Glutamatergic Subtype Markers in Their Descendant Neurons.	P2RY4 SLC17A6	4.48e-05	3	135	2	26972684
Pubmed	Study of the Association of PEAR1, P2Y12, and UGT2A1 Polymorphisms with Platelet Reactivity in Response to Dual Antiplatelet Therapy in Chinese Patients.	UGT2A1 PEAR1	4.48e-05	3	135	2	29635252
Pubmed	Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3.	UGT2A3 UGT2A1	4.48e-05	3	135	2	19858781
Pubmed	Protein expression profiles in murine ventricles modeling catecholaminergic polymorphic ventricular tachycardia: effects of genotype and sex.	RYR2 SCN5A	4.48e-05	3	135	2	32713021
Pubmed	Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.	AQP2 P2RY4	8.93e-05	4	135	2	19423692
Pubmed	A zonal organization of odorant receptor gene expression in the olfactory epithelium.	OR8G1 OR2A4	8.93e-05	4	135	2	7683976
Pubmed	Reassessment of GLUT7 and GLUT9 as Putative Fructose and Glucose Transporters.	SLC2A7 SLC2A2	8.93e-05	4	135	2	28083649
Pubmed	Neuropathic and inflammatory pain are modulated by tuberoinfundibular peptide of 39 residues.	PTH2R SLC17A6	8.93e-05	4	135	2	23878240
Pubmed	The localization of label-retaining cells in mouse nails.	FZD8 LHX2	8.93e-05	4	135	2	17914453
Pubmed	Genetic elucidation of human hyperosmia to isovaleric acid.	OR5AC1 OR11H7	1.48e-04	5	135	2	17973576
Pubmed	Elevating Growth Factor Responsiveness and Axon Regeneration by Modulating Presynaptic Inputs.	GJA10 SLC17A6	1.48e-04	5	135	2	31122676
Pubmed	Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking.	F2RL1 P2RY4	1.48e-04	5	135	2	21219331
Pubmed	An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors.	GPR84 GPR87	1.48e-04	5	135	2	11273702
Pubmed	A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.	L3MBTL1 HTT	2.22e-04	6	135	2	23652004
Pubmed	Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntington's disease mice.	HTT SLC17A6	2.22e-04	6	135	2	36670467
Pubmed	Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.	GYS1 GYS2	2.22e-04	6	135	2	14680475
Pubmed	Trip6 promotes dendritic morphogenesis through dephosphorylated GRIP1-dependent myosin VI and F-actin organization.	TRIP6 MYO5B	2.22e-04	6	135	2	25673849
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRG4 ADGRG7 ADGRE5	2.87e-04	33	135	3	25713288
Pubmed	Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1.	CADM2 SLC17A6	3.10e-04	7	135	2	28628102
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	GYS1 GYS2	3.10e-04	7	135	2	18165236
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TMEM120B CLTCL1 PCNX3 ZDHHC7 PCNX2 MROH1 NBEAL2 SCN5A XXYLT1 PCNX1 AKAP13 ZFYVE26 HTT	3.84e-04	1105	135	13	35748872
Pubmed	Saturation mutagenesis defines novel mouse models of severe spine deformity.	CLCN1 OR2A4	4.12e-04	8	135	2	34142127
Pubmed	A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus.	GPX4 GYS1 GYS2	5.09e-04	40	135	3	12732844
Pubmed	Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3Cre mouse.	DNER LHX2 SLC17A6	5.09e-04	40	135	3	31152445
Pubmed	Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors.	TAAR2 TAAR6	5.29e-04	9	135	2	15718104
Pubmed	Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions.	CADM2 SLC17A6	5.29e-04	9	135	2	18615557
Pubmed	A second class of chemosensory receptors in the olfactory epithelium.	TAAR2 TAAR6	5.29e-04	9	135	2	16878137
Pubmed	L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability.	MCM6 L3MBTL1	5.29e-04	9	135	2	21149733
Pubmed	Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.	RYR2 SCN5A	6.59e-04	10	135	2	32672536
Pubmed	Foxp2 Regulates Identities and Projection Patterns of Thalamic Nuclei During Development.	LHX2 SLC17A6	6.59e-04	10	135	2	27384060
Pubmed	A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.	RYR2 SCN5A	6.59e-04	10	135	2	26897459
Pubmed	Expression of trace amine-associated receptors in the Grueneberg ganglion.	TAAR2 TAAR6	6.59e-04	10	135	2	17556730
Pubmed	Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections.	ADCY1 SLC17A6	6.59e-04	10	135	2	21050275
Pubmed	Netrin-1 receptor DCC is required for the contralateral topography of lamina I anterolateral system neurons.	LHX2 SLC17A6	8.04e-04	11	135	2	32701653
Pubmed	Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.	RYR2 SCN5A	8.04e-04	11	135	2	27766308
Pubmed	Mouse model of muscleblind-like 1 overexpression: skeletal muscle effects and therapeutic promise.	RYR2 CLCN1	8.04e-04	11	135	2	22846424
Pubmed	Lbx1 and Tlx3 are opposing switches in determining GABAergic versus glutamatergic transmitter phenotypes.	LHX2 SLC17A6	9.62e-04	12	135	2	16234809
Pubmed	Phenotypic analysis of mice lacking the Tmprss2-encoded protease.	TMPRSS11E F2RL1	9.62e-04	12	135	2	16428450
Pubmed	Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development.	AQP2 PRKCZ	1.13e-03	13	135	2	26490995
Pubmed	An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents.	CRHR2 SLC17A6	1.13e-03	13	135	2	32259485
Pubmed	Multiple loci influencing hippocampal degeneration identified by genome scan.	SLC1A7 VPS13B	1.13e-03	13	135	2	22745009
Pubmed	Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.	CRHR2 ADORA3 GYS1 GYS2	1.15e-03	117	135	4	18996102
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH7 DNAH12	1.32e-03	14	135	2	9373155
Pubmed	Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.	NHLH1 SLC17A6	1.32e-03	14	135	2	18160702
Pubmed	The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.	MYO5B SLC2A2 SLCO4C1 NHLH1 GPR132	1.47e-03	212	135	5	19521566
Pubmed	Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.	QPCTL CADM2 TMEM18	1.51e-03	58	135	3	20935630
Pubmed	Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells.	RYR2 FZD8	1.52e-03	15	135	2	17360443
Pubmed	Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.	AQP2 PRKCZ	1.73e-03	16	135	2	18177851
Pubmed	A vagal reflex evoked by airway closure.	CRHR2 SLC17A6	1.73e-03	16	135	2	38448588
Pubmed	Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons.	OR52H1 SLC17A6	1.73e-03	16	135	2	25437545
Pubmed	Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.	SLC2A2 NHLH1 ADGRE5	1.92e-03	63	135	3	25053427
Pubmed	Genomic analysis of mouse retinal development.	PCNX3 GPX4 MAU2 SLC1A7 FZD8 LHX2 CLK1 NHLH1 ZFYVE26 RASL10B TMEM64	1.94e-03	1006	135	11	15226823
Pubmed	Natural selection on the olfactory receptor gene family in humans and chimpanzees.	OR11H7 OR4F15	1.96e-03	17	135	2	12908129
Pubmed	Movement-related increases in subthalamic activity optimize locomotion.	HTT SLC17A6	1.96e-03	17	135	2	39068661
Pubmed	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	HUNK PCNX2	1.96e-03	17	135	2	21490949
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	KCNH7 RYR2 CLCN1 SCN5A	2.16e-03	139	135	4	16985003
Pubmed	Huntingtin regulates mammary stem cell division and differentiation.	PRKCZ HTT	2.20e-03	18	135	2	24749073
Pubmed	Genome cross-referencing and XREFdb: implications for the identification and analysis of genes mutated in human disease.	CLCN1 HTT	2.20e-03	18	135	2	9090377
Pubmed	An expression atlas of connexin genes in the mouse.	GJA8 GJA10	2.20e-03	18	135	2	15081111
Pubmed	The novel mouse connexin39 gene is expressed in developing striated muscle fibers.	GJA8 GJA10	2.20e-03	18	135	2	15466892
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	NPHP1 SLC1A7 SLC2A2 RYR2	2.39e-03	143	135	4	20424473
Pubmed	An update on connexin genes and their nomenclature in mouse and man.	GJA8 GJA10	2.45e-03	19	135	2	14681012
Pubmed	Neuroretina specification in mouse embryos requires Six3-mediated suppression of Wnt8b in the anterior neural plate.	FZD8 LHX2	2.45e-03	19	135	2	20890044
Pubmed	Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.	NCR3 TMEM18	2.71e-03	20	135	2	19079260
Pubmed	Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression.	LHX2 SLC17A6	2.71e-03	20	135	2	20696379
Pubmed	Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.	NPHP1 AQP2	2.71e-03	20	135	2	17251353
Pubmed	Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain.	LHX2 NHLH1	2.99e-03	21	135	2	29867344
Pubmed	Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.	RYR2 SCN5A	2.99e-03	21	135	2	28302382
Pubmed	The DNA sequence and analysis of human chromosome 6.	STXBP5 SMIM8 TAAR2 OR2B3 TAAR6 NCR3 VNN1 OR2A4	3.05e-03	622	135	8	14574404
Pubmed	Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.	NHLH1 SLC17A6	3.28e-03	22	135	2	22726835
Pubmed	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	HUNK PRKCZ	3.28e-03	22	135	2	21107309
Pubmed	The imprinted Phlda2 gene regulates extraembryonic energy stores.	GYS1 GYS2	3.28e-03	22	135	2	19884348
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ASTE1 CHD9 MAU2 PTH2R CLK1 NBEAL2 SLC5A6 GYS2 XXYLT1 PRKCZ TMEM18 PEAR1	3.36e-03	1242	135	12	30973865
Pubmed	Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes.	MAGEA12 MCM6 PSMD6	3.52e-03	78	135	3	29426014
Pubmed	Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways.	LHX2 SLC17A6	3.59e-03	23	135	2	15229646
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	TAAR2 ADGRG4 ADGRG7	3.65e-03	79	135	3	12679517
Cytoband	19p13.11	CALR3 TMEM221 MAU2 YJEFN3	6.84e-05	73	136	4	19p13.11
Cytoband	Ensembl 112 genes in cytogenetic band chr6q23	TAAR2 TAAR6 VNN1 OR2A4	4.49e-04	119	136	4	chr6q23
Cytoband	Xq13	CXCR3 P2RY4	6.65e-04	13	136	2	Xq13
GeneFamily	Adhesion G protein-coupled receptors, subfamily G	ADGRG4 ADGRG7	6.50e-04	7	102	2	917
GeneFamily	Trace amine receptors	TAAR2 TAAR6	1.11e-03	9	102	2	188
GeneFamily	Glycosyl transferases group 1 domain containing	GYS1 GYS2	1.38e-03	10	102	2	427
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)\|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CLTCL1 STXBP5 MBOAT2 SLCO4C1 VNN1 GYS1 SCN5A	1.83e-06	192	133	7	072281344d58e85c9a290750b488d0c101f75d54
Disease	Arrhythmogenic Right Ventricular Dysplasia	RYR2 SCN5A	5.07e-05	3	122	2	C0349788
Disease	Cadmium poisoning	GPX4 HTT	5.07e-05	3	122	2	C0006635
Disease	Lafora disease (implicated_via_orthology)	GYS1 GYS2	1.01e-04	4	122	2	DOID:3534 (implicated_via_orthology)
Disease	primary ciliary dyskinesia (is_implicated_in)	DNAH7 BRWD1	2.52e-04	6	122	2	DOID:9562 (is_implicated_in)
Disease	glycogen storage disease (is_implicated_in)	SLC2A2 GYS2	5.99e-04	9	122	2	DOID:2747 (is_implicated_in)
Disease	Tachycardia, Ventricular	RYR2 SCN5A	9.10e-04	11	122	2	C0042514
Disease	Long QT Syndrome	RYR2 SCN5A	9.10e-04	11	122	2	C0023976
Disease	familial atrial fibrillation (is_implicated_in)	NUP155 SCN5A	1.49e-03	14	122	2	DOID:0050650 (is_implicated_in)
Disease	amino acid measurement	CLTCL1 SLC2A7 OR8U3 DNAH7 PTH2R RYR2 DNAH12 ZBTB40 HTT	2.07e-03	678	122	9	EFO_0005134
Disease	reasoning	HUNK PRKCZ	2.77e-03	19	122	2	EFO_0004350
Disease	neurodegenerative disease (implicated_via_orthology)	SLC1A7 PSMD6 HTT SLC17A6	3.14e-03	145	122	4	DOID:1289 (implicated_via_orthology)
Disease	ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)	NUP155 SCN5A	3.71e-03	22	122	2	C1843687

Protein segments in the cluster

Peptide	Gene	Start	Entry
SVNHYGLLIDRFCLT	NT5C1B	396	Q96P26
LLACISFDRYLNIVH	CXCR3	141	P49682
LVGCHVSVLRAAFYV	AQP2	76	P41181
IRCKVDGFTHLYTLI	CALR3	161	Q96L12
VVSLGITIHFYSCLF	ADORA3	71	P0DMS8
VGVCITAAVALHYFL	ADGRG4	2806	Q8IZF6
GCLLRTYVLHILTRS	GJA10	151	Q969M2
IFTTHATLLGRYLCA	GYS2	201	P54840
RCRLVAGLLHYCFLA	ADGRE5	611	P48960
VFYLVFLGSTLRHCT	AKAP13	31	Q12802
CVQRLRVFISHYTLL	ARHGEF33	426	A8MVX0
ILGHLSSVYCVAFDR	BRWD3	176	Q6RI45
CTAIAALLHYFLLVT	ADGRG7	526	Q96K78
VVLHERYLLNIFTCF	DISP1	656	Q96F81
TKIVIDGYALFHRLC	ASTE1	26	Q2TB18
HICIVFELLGLSTYD	CLK1	236	P49759
SIGHVVQLLYRASCF	RC3H1	241	Q5TC82
VISYRGCITQLFFLH	OR4N4C	91	A0A096LPK9
FLGLLASYAVILCHV	OR4N4C	211	A0A096LPK9
HNLCRILAVFLAEYL	QPCTL	366	Q9NXS2
LSLVFHYVFLQICRA	IQCH	911	Q86VS3
LIQLATCHFALGEYR	INTS10	496	Q9NVR2
HVYIIAGACLSLGFR	ANAPC1	1461	Q9H1A4
HSRFEVICYLATFLL	CFAP99	81	D6REC4
ALSYVHILCAVFRLP	OR52E2	216	Q8NGJ4
LGDYVHACSLRGVLL	MUC6	636	Q6W4X9
CSYIFIIASILHIRS	OR8G1	216	Q15617
GFSEYCRISNLIVLH	MCM6	716	Q14566
CGSHLALVILFYGAI	OR1F12P	241	Q8NHA8
TISYAGCVAHLIIFL	OR2B3	91	O76000
FILVSSGYIAHAVLR	OR2G2	216	Q8NGZ5
RIGHLYILVTCLGLS	MAGEA12	171	P43365
YLVRFLSDLVNCHVI	NCBP1	126	Q09161
HDASIYVCRVEVLGL	NCR3	101	O14931
RHVVATLLGLYLALF	MBOAT2	56	Q6ZWT7
LGIICVFAYIAGHSI	SLC2A7	381	Q6PXP3
TLVHCGDVLTALYFL	KCNH7	771	Q9NS40
FVLYVGALATERCSH	LMLN	211	Q96KR4
IYLGDIASLCVGHLA	LOXHD1	1866	Q8IVV2
SHLRRFCLQYGAALI	DYNC1LI2	256	O43237
FCGLLVAVSYHLSRQ	PCNX1	1201	Q96RV3
AFCGLLVALSYHLSR	PCNX2	1036	A6NKB5
SVFCGLLVALSYHLS	PCNX3	986	Q9H6A9
LTVAEVCGYRLRLHF	L3MBTL1	326	Q9Y468
SHLCAVLVFYVPLIG	OR51D1	256	Q8NGF3
IISYRGCITQLFFLH	OR4N2	91	Q8NGD1
VISYRGCITQLFFLH	OR4N4	91	Q8N0Y3
FLGLLASYAVILCHV	OR4N4	211	Q8N0Y3
SLVVALVALFIGYRH	PEAR1	766	Q5VY43
HILIIAGRSISGLYC	SLC2A2	151	P11168
YLGHCVSVAALVAAF	CRHR2	121	Q13324
AFHISLYRDTGVCIL	DNAH12	841	Q6ZR08
SLVYCRLHFEALLQG	LHX2	161	P50458
CLAHLAVVLLFYGTI	OR13J1	241	Q8NGT2
CLYFLATSSIIGLIH	OR4F15	141	Q8NGB8
VKSALILCYGHVAAR	MROH1	736	Q8NDA8
LYLLTFCGIRVSEHG	OOSP4A	71	A0A2R8YFL7
ILIGCYIAISRYIHK	GPR87	221	Q9BY21
LSSVGIFYCLIHRQV	GPR84	191	Q9NQS5
CQLLAVTHAGVRLYF	NUP155	356	O75694
CASHLIAVTLFYGAL	OR5AS1	241	Q8N127
CGSHLAVVLLFYSTI	OR1F1	241	O43749
FSHLCVIGLVYGTAI	OR2A4	241	O95047
SAIHVGLLFRLTFCR	OR5AC1	156	P0C628
CSVLFLTCISVHRYL	P2RY4	121	P51582
HVYALYIVALCLSTL	F2RL1	321	P55085
LFVSVGYLVRLVAGH	FZD8	321	Q9H461
CFLVACVLYLHITRV	ADCY1	646	Q08828
ICRALLAYCLVHYRG	CHD9	1531	Q3L8U1
ILRLAICYISYLNHV	NHLH1	116	Q02575
SLIYCVHFILEAVAV	HTT	2306	P42858
HSLYVFVRNFVCRIG	DOCK2	221	Q92608
YSVTVVCGLVLHGLF	SLC1A7	296	O00341
HGLNRTGYLICRYLI	DUSP11	201	O75319
LFVPCSRVGHIYRLE	GALNT7	431	Q86SF2
FRLEGTLLRTYICHI	GJA8	141	P48165
LTDRCYRTLFGALHL	DNAH7	1306	Q8WXX0
VLSNRACHILAIYFL	HUNK	366	P57058
TLCSIFLLGRYLARH	CADM2	381	Q8N3J6
RILGHLSAVYCVAFD	BRWD1	181	Q9NSI6
YRLAAHLGSALVLYC	COX15	221	Q7KZN9
LHARYAECGLRILAF	GPX4	86	P36969
IFTTHATLLGRYLCA	GYS1	201	P13807
RHSLYIIIGALCVAF	DNER	636	Q8NFT8
QHRLFYVALLTICLG	SLC15A5	151	A6NIM6
RLTACSLVLLGHIFY	MAU2	496	Q9Y6X3
AILHTVISFFCIIGY	RYR2	4576	Q92736
CSIHLLIFYRQILGD	NPHP1	576	O15259
TVALGHRLDIVFYLL	PSMD6	131	Q15008
CGSHLVVVSLFYGAI	OR11H7	241	Q8NGC8
LIAVSYAHILCAVFG	OR52H1	221	Q8NGJ2
LLLTGLSCVYRLHAA	FAM180B	121	Q6P0A1
LISACIFILVGIVHY	GPR132	161	Q9UNW8
LSRVCGLLRQLHTAY	PLIN4	1256	Q96Q06
GLRSVHAYILVYDIC	RASL10B	81	Q96S79
FHLCFISIDRYIAVT	TAAR6	121	Q96RI8
LLGAVACRFVLHYRV	TMEM120B	141	A0PK00
LVLSLAIGLYHACRG	SLC5A6	36	Q9Y289
SHLAVVCLFYGTGLV	OR7E24	261	Q6IFN5
VRLDICRQLFHLIYG	NBEAL2	1256	Q6ZNJ1
FTGECIVKLAALRHY	SCN5A	1571	Q14524
GISYCLFVLHRVRLP	SPPL2C	356	Q8IUH8
ALFHTVITFRLTYCG	OR8U3	156	Q8NH85
LCIAGVSAHVIIYRF	STXBP5	516	Q5T5C0
CFYRELVVVHGLSAA	B3GNT9	356	Q6UX72
IVCDRFGFVHDLVLY	CLTCL1	776	P53675
RHLLYVGGSLCLTAV	CMTM1	106	Q8IZ96
ICCGLLGAVFVYLHR	CLCN1	356	P35523
YIGNIEHLVIASFCL	NLRP9	571	Q7RTR0
VLAVCIGLTVHYVRY	TMPRSS11E	31	Q9UL52
YRQFHIIVCGLDSII	UBA3	156	Q8TBC4
SAARVHYGCVIFVRI	SLC17A6	171	Q9P2U8
ALCFASLALVRRYLH	TMEM64	131	Q6YI46
VRIVALDRSFHIGCY	TRIP6	416	Q15654
LHTVEGRYYLQICTL	VNN1	386	O95497
LCSTLILVAVFKYGH	PIGX	241	Q8TBF5
GFLLHYCLLAVTQGI	SLCO4C1	106	Q6ZQN7
ASTCSRLFYILLHVG	SERINC4	56	A6NH21
RLFYILLHVGASAIC	SERINC4	61	A6NH21
AVGLVCARHLRVFEY	YJEFN3	131	A6XGL0
TLSLCVAYIGYLHAI	SMIM8	56	Q96KF7
IFHLCSVAIDRFYAI	TAAR2	131	Q9P1P5
VAILIIGYFRRLHCT	PTH2R	161	P49190
VHAATLICRGLDYFS	TMEM245	176	Q9H330
FLYDCRLLRHVALGL	TMEM221	111	A6NGB7
GFCTRAIVLTYQEHL	VPS13B	3226	Q7Z7G8
HYSIDVIGFLLACVA	UGT2A3	486	Q6UWM9
YIALSSVHALILCGF	ZDHHC7	181	Q9NXF8
LIAAIVLSCDYRFHA	TAS2R8	146	Q9NYW2
RIGASLLFVTEHCYV	VN1R17P	161	Q8TDU5
FGRLHNDCIYILIDT	VWA3B	501	Q502W6
YHSLDVIGFLLVCVT	UGT2A1	486	P0DTE4
AGSFHILVVYCGDLI	WDR87	76	Q6ZQQ6
IISFYVRHSCLREAL	ZFYVE26	2176	Q68DK2
SRSYRLQIGHFLCLV	TMEM18	46	Q96B42
CTISIGTIYFRAHKL	ZBTB40	26	Q9NUA8
RLGAVRSHYCALLLA	XXYLT1	16	Q8NBI6
RSHYCALLLAAALAV	XXYLT1	21	Q8NBI6
CIALNFLHERGIIYR	PRKCZ	361	Q05513
VYLSNFCRLLGVEHS	MYO5B	356	Q9ULV0