Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoCivatte bodies

XYLT1 ABCC6

5.33e-053222HP:0025115
HumanPhenoWhite oral mucosal macule

XYLT1 ABCC6

5.33e-053222HP:0033026
HumanPhenoYellow papule

XYLT1 ABCC6

1.06e-044222HP:0025507
HumanPhenoRetinal peau d'orange

XYLT1 ABCC6

1.06e-044222HP:0033027
HumanPhenoWeak pulse

XYLT1 ABCC6

1.06e-044222HP:0032553
DomainSAM_2

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

2.53e-0743605PF07647
DomainLiprin

PPFIA2 PPFIA1 PPFIA3

6.26e-076603IPR029515
DomainSAM

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

9.22e-0688605SM00454
DomainSAM_DOMAIN

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

1.34e-0595605PS50105
DomainSAM

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

1.48e-0597605IPR001660
Domain-

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

2.28e-051066051.10.150.50
DomainSAM/pointed

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

3.67e-05117605IPR013761
DomainSAM_1

PPFIA2 PPFIA1 PPFIA3 EPHA7

6.72e-0568604PF00536
DomainEGF-like_CS

MALRD1 LRP1 ADAM22 EGFL6 CRB1 EPHA7

1.87e-04261606IPR013032
DomainEGF_2

MALRD1 LRP1 ADAM22 EGFL6 CRB1 EPHA7

2.03e-04265606PS01186
DomainEGF_3

MALRD1 LRP1 ADAM22 EGFL6 CRB1

9.40e-04235605PS50026
DomainEGF

MALRD1 LRP1 ADAM22 EGFL6 CRB1

9.40e-04235605SM00181
DomainEGF-like_dom

MALRD1 LRP1 ADAM22 EGFL6 CRB1

1.22e-03249605IPR000742
DomainNAD/diacylglycerol_kinase

NADK2 DGKH

1.34e-0317602IPR016064
DomainMAM

MALRD1 EGFL6

1.34e-0317602SM00137
DomainEGF_1

MALRD1 LRP1 ADAM22 EGFL6 CRB1

1.35e-03255605PS00022
DomainMAM

MALRD1 EGFL6

1.50e-0318602PF00629
DomainMAM_dom

MALRD1 EGFL6

1.50e-0318602IPR000998
DomainMAM_2

MALRD1 EGFL6

1.50e-0318602PS50060
DomainGrowth_fac_rcpt_

LRP1 EGFL6 CRB1 EPHA7

1.59e-03156604IPR009030
DomainEPHD

BRPF1 KDM4B

2.25e-0322602PS51805
DomaintRNA-bd_arm

PPFIA2 PPFIA3

2.68e-0324602IPR010978
DomainEphrin_rec_like

EPHA7 TNFRSF4

2.90e-0325602SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHA7 TNFRSF4

2.90e-0325602IPR011641
DomainPHD

DPF1 BRPF1 KDM4B

2.94e-0389603SM00249
DomainZnf_PHD

DPF1 BRPF1 KDM4B

3.13e-0391603IPR001965
DomainZF_PHD_2

DPF1 BRPF1 KDM4B

3.54e-0395603PS50016
DomainZF_PHD_1

DPF1 BRPF1 KDM4B

3.64e-0396603PS01359
DomainEGF_Ca-bd_CS

LRP1 EGFL6 CRB1

3.75e-0397603IPR018097
DomainEGF_CA

LRP1 EGFL6 CRB1

3.97e-0399603PS01187
DomainASX_HYDROXYL

LRP1 EGFL6 CRB1

4.09e-03100603PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 EGFL6 CRB1

4.81e-03106603IPR000152
DomainConA-like_dom

MALRD1 TRIM14 EGFL6 CRB1

5.37e-03219604IPR013320
DomainEGF_CA

LRP1 EGFL6 CRB1

7.10e-03122603SM00179
DomainLDLR_class-A_CS

MALRD1 LRP1

7.32e-0340602IPR023415
DomainEGF-like_Ca-bd_dom

LRP1 EGFL6 CRB1

7.42e-03124603IPR001881
DomainEGF

MALRD1 LRP1 CRB1

7.75e-03126603PF00008
DomainLdl_recept_a

MALRD1 LRP1

9.19e-0345602PF00057
Domain-

MALRD1 LRP1

9.59e-03466024.10.400.10
PathwayKEGG_GLYCEROLIPID_METABOLISM

MBOAT1 DGKH ALDH3A2 AKR1B1

1.58e-0549444M15902
PathwayREACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

1.87e-0517443MM14907
PathwayREACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

1.87e-0517443M93
PathwayREACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

2.24e-0518443M13015
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

2.24e-0518443MM14702
PathwayREACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

2.24e-0518443MM14703
PathwayREACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

2.24e-0518443M27043
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PPFIA2 PPFIA1 PPFIA3

3.12e-0520443M27290
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

PPFIA2 PPFIA1 PPFIA3

3.12e-0520443MM14991
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

4.81e-0523443MM14852
PathwayREACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

4.81e-0523443M12627
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

5.49e-0524443MM14834
PathwayREACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

5.49e-0524443M630
PathwayKEGG_GLYCEROPHOSPHOLIPID_METABOLISM

MBOAT1 PTDSS1 DGKH PLD2

9.46e-0577444M9131
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

SLC6A4 PPFIA2 PPFIA1 PPFIA3 ADCY8

4.84e-04211445MM14502
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

5.32e-0451443M4281
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

PPFIA2 PPFIA1 PPFIA3

5.32e-0451443MM14499
PathwayREACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES

PPFIA2 PPFIA1 PPFIA3

1.18e-0367443MM15327
PathwayWP_REGULATION_OF_WNT_BCATENIN_SIGNALING_BY_SMALL_MOLECULE_COMPOUNDS

MBOAT1 LRP1

1.26e-0317442M39525
PathwayREACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE

EFNA4 EPHA7

1.41e-0318442MM15023
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

SLC6A4 PPFIA2 PPFIA1 PPFIA3 ADCY8

1.46e-03270445M15514
Pubmed

The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing.

PPFIA2 PPFIA1 PPFIA3

5.12e-08561319013515
Pubmed

Analyses of the spatiotemporal expression and subcellular localization of liprin-α proteins.

PPFIA2 PPFIA1 PPFIA3

1.02e-07661321618221
Pubmed

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.

PPFIA2 PPFIA1 PPFIA3

4.28e-07961312923177
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PPFIA2 PPFIA1 PPFIA3

1.12e-06126139624153
Pubmed

AVPR1A and SLC6A4 polymorphisms in choral singers and non-musicians: a gene association study.

SLC6A4 AVPR1A

3.03e-06261222384070
Pubmed

AVPR1a and SLC6A4 gene polymorphisms are associated with creative dance performance.

SLC6A4 AVPR1A

3.03e-06261216205790
Pubmed

PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure.

PPFIA2 PPFIA3

3.03e-06261234031393
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP1 NFXL1 DMD CRB1

7.62e-067161433541421
Pubmed

Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses.

PPFIA2 PPFIA3

9.07e-06361229439199
Pubmed

Pseudoxanthoma Elasticum

XYLT1 ABCC6

9.07e-06361220301292
Pubmed

Association between AVPR1A, DRD2, and ASPM and endophenotypes of communication disorders.

AVPR1A ASPM

9.07e-06361224849541
Pubmed

PRMT5 Enables Robust STAT3 Activation via Arginine Symmetric Dimethylation of SMAD7.

PRMT5 SMAD7

9.07e-06361234026434
Pubmed

Association study of polymorphisms in LRP1, tau and 5-HTT genes and Alzheimer's disease in a sample of Colombian patients.

SLC6A4 LRP1

9.07e-06361216362633
Pubmed

Protein kinase C-epsilon regulates sphingosine 1-phosphate-mediated migration of human lung endothelial cells through activation of phospholipase D2, protein kinase C-zeta, and Rac1.

PRKCZ PLD2

1.81e-05461218296444
Pubmed

Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.

PPFIA2 PPFIA1 PPFIA3

2.02e-053061316186258
Pubmed

The synaptic vesicle cycle.

PPFIA2 PPFIA1 PPFIA3

2.23e-053161315217342
Pubmed

Prmt5 is a regulator of muscle stem cell expansion in adult mice.

PRMT5 DMD

3.02e-05561226028225
Pubmed

Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes.

EFNA4 EPHA7

4.52e-05661212895420
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SLC6A4 CIAO1 PPFIA1 LRP1 PLD2 DMD ALDH3A2 PAAF1 TRIM14

4.80e-0597461928675297
Pubmed

Ephrin-A binding and EphA receptor expression delineate the matrix compartment of the striatum.

EFNA4 EPHA7

6.32e-05761210366629
Pubmed

Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting.

PPFIA2 PPFIA1

6.32e-05761211931740
Pubmed

A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

PPFIA2 PPFIA1 PPFIA3

7.38e-054661318782753
Pubmed

Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.

EFNA4 EPHA7

8.42e-05861210774725
Pubmed

Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.

PPFIA2 PPFIA1

1.08e-04961212629171
Pubmed

Topographic guidance labels in a sensory projection to the forebrain.

EFNA4 EPHA7

1.08e-0496129883724
Pubmed

Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5.

PRMT5 SMAD7

1.35e-041061219032343
Pubmed

Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK.

PPFIA2 PPFIA1

1.35e-041061218054859
Pubmed

EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.

SLC6A4 EPHA7

1.35e-041061228197551
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

PRMT5 MKRN2 PTDSS1 NFXL1

1.36e-0414861435676246
Pubmed

Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5.

EFNA4 EPHA7

1.65e-041161210559410
Pubmed

Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues.

EFNA4 EPHA7

1.65e-041161215517401
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

PPFIA2 PPFIA3

1.65e-041161234767769
Pubmed

PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors.

PRMT5 DMD

1.65e-041161237883229
Pubmed

Transcription factor Lmo4 defines the shape of functional areas in developing cortices and regulates sensorimotor control.

EFNA4 EPHA7

1.97e-041261219111533
Pubmed

Ephrin/ephrin receptor expression during early stages of mouse inner ear development.

EFNA4 EPHA7

1.97e-041261221465626
Pubmed

EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion.

EFNA4 EPHA7

1.97e-041261219247962
Pubmed

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.

ASPM PRKCZ

1.97e-041261222031545
Pubmed

Eph-ephrin A system regulates murine blastocyst attachment and spreading.

EFNA4 EPHA7

2.33e-041361217039519
Pubmed

EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.

EFNA4 EPHA7

2.33e-041361212528186
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

PPFIA1 SEC24B PTDSS1 NFXL1 ALDH3A2 STX10 EIF2AK3 ADAM22

2.50e-0495261838569033
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

RUNDC3B SEC24B ALDH3A2 STX10 EIF2AK3 ADAM22

2.54e-0450461634432599
Pubmed

Ephrin-A3 is required for tonotopic map precision and auditory functions in the mouse auditory brainstem.

EFNA4 EPHA7

2.72e-041461234235739
Pubmed

Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.

ASPM PRKCZ

2.72e-041461227974163
Pubmed

A role for the EphA family in the topographic targeting of vomeronasal axons.

EFNA4 EPHA7

2.72e-041461211222144
Pubmed

Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.

EFNA4 EPHA7

3.57e-04166128755474
Pubmed

Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.

PPFIA1 PPFIA3 EPHA7

3.69e-047961329121065
Pubmed

Shox2 function couples neural, muscular and skeletal development in the proximal forelimb.

DMD EPHA7

4.05e-041761221156168
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

PRMT5 MCM3AP SEC24B DMD

4.05e-0419761420811636
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

SEC24B PTDSS1 NFXL1 ALDH3A2 STX10 EIF2AK3

4.79e-0456861637774976
Pubmed

mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.

PPFIA2 PPFIA1

5.63e-042061223791195
Pubmed

Multiple roles of EPH receptors and ephrins in neural development.

EFNA4 EPHA7

5.63e-042061211256076
Pubmed

The ephrins and Eph receptors in neural development.

EFNA4 EPHA7

5.63e-04206129530499
Pubmed

Eph receptors and ephrins: effectors of morphogenesis.

EFNA4 EPHA7

5.63e-042061210207129
Pubmed

The Eph family receptors and ligands.

EFNA4 EPHA7

5.63e-04206129576626
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

DPF1 IBTK PPFIA2 PPFIA3

5.92e-0421861433378226
Pubmed

Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.

EFNA4 EPHA7

6.22e-04216129267020
Pubmed

Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.

EFNA4 EPHA7

6.22e-042161210495276
Pubmed

Developmental expression of Eph and ephrin family genes in mammalian small intestine.

EFNA4 EPHA7

6.22e-042161220112066
Pubmed

Roles of Eph receptors and ephrins in segmental patterning.

EFNA4 EPHA7

6.22e-042161211128993
Pubmed

Eph receptors and ephrins: regulators of guidance and assembly.

EFNA4 EPHA7

6.22e-042161210730216
Pubmed

The RNF146 and tankyrase pathway maintains the junctional Crumbs complex through regulation of angiomotin.

PRKCZ CRB1

6.83e-042261227521426
Pubmed

CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.

PPFIA1 PPFIA3

6.83e-042261234187934
Pubmed

Positional cloning of the mouse saccharin preference (Sac) locus.

PRKCZ TNFRSF4

6.83e-042261211555487
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DPF1 CIAO1 PPFIA1 BRPF1 MCM3AP ASPM LRP1 PPFIA3

7.15e-04111661831753913
Pubmed

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

ASPM CRB1

7.48e-042361224925725
Pubmed

Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye.

PRKCZ CRB1

7.48e-042361225636444
Pubmed

Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.

EFNA4 EPHA7

7.48e-042361219542359
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

PPFIA1 BRPF1 ASPM DMD

7.72e-0423461436243803
Pubmed

Crumbs3 is essential for proper epithelial development and viability.

PRKCZ CRB1

8.15e-042461224164893
Pubmed

Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.

EFNA4 EPHA7

8.15e-042461216446123
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

AVPR1A LRP1 DMD

8.47e-0410561330280653
Pubmed

Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.

SLC6A4 EPHA7

9.57e-042661218957218
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

PPFIA2 PPFIA1 PPFIA3

9.69e-0411061327889896
Pubmed

PRMT5 is essential for the maintenance of chondrogenic progenitor cells in the limb bud.

PRMT5 SMAD7

1.03e-032761227827819
Pubmed

The basement membrane of hair follicle stem cells is a muscle cell niche.

DMD EGFL6

1.11e-032861221335239
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

FZD9 ADAM22 EPHA7

1.16e-0311761317145500
Pubmed

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

LRP1 ASB1

1.28e-033061221946350
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

ASPM ADAM22

1.28e-033061219054571
Pubmed

Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.

EFNA4 EPHA7

1.28e-033061238636517
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

SEC24B NFXL1 ALDH3A2 STX10 EIF2AK3

1.38e-0346861531056421
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

DPF1 RNF32 IBTK BRPF1 MKRN2 KDM4B

1.51e-0370961622988430
Pubmed

Ctip1 Controls Acquisition of Sensory Area Identity and Establishment of Sensory Input Fields in the Developing Neocortex.

SLC6A4 EPHA7

1.54e-033361227100196
Pubmed

Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.

DEFB124 DEFB135

1.73e-033561216033865
Cytoband16p12.3

XYLT1 TMC7

9.48e-043461216p12.3
CytobandEnsembl 112 genes in cytogenetic band chr16p12

XYLT1 TMC7 SCNN1G

1.59e-03172613chr16p12
GeneFamilySterile alpha motif domain containing

PPFIA2 PPFIA1 DGKH PPFIA3 EPHA7

2.55e-0688455760
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MCM3AP ASPM DGKH ALDH3A2 TNFRSF4

3.96e-06173615efb8072475000888efe088d00e870c56ffad4172
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MCM3AP ASPM DGKH ALDH3A2 TNFRSF4

4.08e-0617461558300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A4 MBOAT1 SCNN1G SPAG16

4.94e-0514761464fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SLC22A9 TMC7 IL20RA ASB1

5.21e-05149614a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 AVPR1A SCNN1G ADAM22

5.77e-051536149b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRG3 RUNDC3B MIF4GD TNFRSF4

6.54e-0515861498fd640ef0bd0014b8c38b81bd5160efcf42f23c
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Lymphocytic|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRG3 RUNDC3B MIF4GD TNFRSF4

6.54e-051586144d2d69fbb880b5232d7867b4d099d0f047ca9ebe
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FZD9 PPFIA2 DGKH DMD

6.86e-0516061429c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFXL1 RTN4IP1 PRKCZ SNN

7.03e-05161614249c2b97cc25de5053f5048ee354615df49b2081
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPF1 PPFIA2 ASPM EGFL6

7.38e-0516361451dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 AVPR1A SCNN1G ADAM22

7.55e-051646146fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

BRPF1 MCM3AP RTN4IP1 ACVR1C

8.48e-051696146abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPFIA2 LRP1 DGKH DMD

8.68e-051706145570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 MBOAT1 ACVR1C EPHA7

9.71e-051756141b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPF1 ASPM RTN4IP1 ADCY8

9.71e-0517561415c69dd5635c9251c535f1e22467712e9667ae92
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD9 EFNA4 MBOAT1 PLD2

9.71e-05175614c1a8a55af825d5913095f919fa860828df9c273e
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 MBOAT1 ACVR1C EPHA7

9.71e-05175614a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD9 EFNA4 MBOAT1 PLD2

9.71e-0517561478b453e220218c84557f244ef7a760e4a1952761
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 PPFIA2 LRP1 DMD

9.92e-051766149bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 PPFIA2 LRP1 DMD

9.92e-051766143f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPF1 AVPR1A ASPM AKR1B1

1.01e-0417761475049e5372d14edeb5768339359396b73a85c2cc
ToppCelldroplet-Limb_Muscle-nan-24m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 SLC6A4 PPFIA1 RTN4IP1

1.04e-04178614f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

XYLT1 FZD9 AVPR1A SOBP

1.04e-041786148591a40fced747ac16b3e8ebc7a22dfb3ad76da2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 DMD ADAM22 EPHA7

1.06e-0417961402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 AVPR1A SCNN1G ADAM22

1.08e-04180614788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell3'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD9 IL20RA ADAM22 TNFRSF4

1.13e-0418261482d6f72649c7dd4d64a84a9795edebdef2f285d6
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFNA4 MBOAT1 AVPR1A SCNN1G

1.13e-04182614fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPFIA2 DGKH DMD EGFL6

1.15e-041836148a799807fbf24456a9811e0c64068187940a2f71
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

XYLT1 FZD9 SOBP PRKCZ

1.18e-041846141e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOBP PPFIA2 DMD EGFL6

1.18e-04184614327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 MIF4GD EIF2AK3 SNN

1.20e-04185614bf4dbb5f139566750e50a81eb062ed8b9e5786c3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 SCNN1G SPAG16 ADAM22

1.20e-04185614d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCelldroplet-Mammary_Gland-nan-3m-Lymphocytic-B_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XYLT1 MIF4GD EIF2AK3 SNN

1.20e-041856143d035bb453a5942411da4eb8b3a1ca0961a089b2
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 EFNA4 ACVR1C EGFL6

1.23e-04186614246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 EFNA4 ACVR1C EGFL6

1.23e-04186614ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SOBP NADK2 DMD ABCC6

1.25e-04187614f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteochondral_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AVPR1A DEFB124 PPFIA2 EGFL6

1.31e-041896141ff4f8da572bdc6356e9df9f41a7f62c81d4c570
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DPF1 SOBP ADCY8 EGFL6

1.31e-04189614473b01c9162b12b90a617c600238436177a0d18d
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCNN1G PRKCZ DMD ABCC6

1.31e-041896147659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 SCNN1G SPAG16 ADAM22

1.31e-04189614fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

TMC7 SCNN1G PRKCZ ALDH3A2

1.31e-041896145a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SLC6A4 SCNN1G RTN4IP1 AKR1B1

1.33e-0419061405a2c3549b68f49081723bf35db14974274419d5
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PPFIA2 DGKH DMD EGFL6

1.33e-04190614d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 SOBP LRP1 DMD

1.36e-04191614a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

PPFIA2 DGKH DMD EGFL6

1.36e-04191614fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

XYLT1 SOBP LRP1 DMD

1.36e-041916148f6d592edc32fdb901af30501d4360512334e8c2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PPFIA2 DGKH DMD EGFL6

1.39e-041926145000440dc1ed17e7474d340921bdff945646f27e
ToppCell(3)_Chondrocytes|World / Cell class and subclass of bone marrow stroma cells in homeostatis

XYLT1 FZD9 SOBP PRKCZ

1.39e-041926145d2b4830d025d3dbdf5623ce1c28d1036e1984a8
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

PPFIA2 ASPM DGKH EPHA7

1.44e-041946145759c83308df017f1faae248e9b85388e25254f0
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM SNN EGFL6 SMAD7

1.44e-041946148ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell(3)_Chondrocytes-(34)_Chondro-progen|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FZD9 SOBP PRKCZ EGFL6

1.47e-04195614d00cb2fab25f2026a9668a7f0686938a2e7155e2
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPFIA2 DGKH DMD EGFL6

1.50e-04196614754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

XYLT1 FZD9 SOBP PRKCZ

1.53e-04197614a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LRP1 DMD ADAM22 EPHA7

1.59e-0419961438cfd367ee8c074c11ba54edeb7a001e375e2687
DiseaseColorectal Carcinoma

SLC22A9 MCM3AP LRP1 SCNN1G PRKCZ DMD ABCC6 ADCY8 SMAD7 EPHA7

1.41e-067026010C0009402
DiseasePseudoxanthoma Elasticum, Incomplete

XYLT1 ABCC6

1.22e-053602C1867450
DiseasePseudoxanthoma elasticum

XYLT1 ABCC6

1.22e-053602cv:C0033847
DiseaseAutosomal recessive inherited pseudoxanthoma elasticum

XYLT1 ABCC6

1.22e-053602cv:C1275116
DiseasePSEUDOXANTHOMA ELASTICUM

XYLT1 ABCC6

1.22e-053602264800
DiseaseGronblad-Strandberg Syndrome

XYLT1 ABCC6

1.22e-053602C0376359
DiseasePseudoxanthoma Elasticum

XYLT1 ABCC6

2.43e-054602C0033847
Diseasebrain edema (implicated_via_orthology)

AVPR1A DMD

6.07e-056602DOID:4724 (implicated_via_orthology)
Diseasepseudoxanthoma elasticum (is_implicated_in)

XYLT1 ABCC6

1.45e-049602DOID:2738 (is_implicated_in)
Diseaselip morphology measurement

XYLT1 DMD SPAG16 CRB1

6.01e-04189604EFO_0007845
DiseaseCardiac Hypertrophy

PRKCZ PLD2 DMD

6.31e-0482603C1383860
DiseaseCardiomegaly

PRKCZ PLD2 DMD

6.31e-0482603C0018800
Diseaseretinal degeneration (biomarker_via_orthology)

DMD ACVR1C

1.49e-0328602DOID:8466 (biomarker_via_orthology)
Diseasepappalysin‐1 measurement

PRG3 UROC1

1.59e-0329602EFO_0010618

Protein segments in the cluster

PeptideGeneStartEntry
WVAVCKQVCTRVGTY

nan

26

Q6ZRU5
KQVCTRVGTYAVCWC

nan

31

Q6ZRU5
LRKTCCWINETYLAR

ADCY8

771

P40145
YGWRRNSKGVCEATC

EGFL6

51

Q8IUX8
KVRYICSALGCRQWD

EIF2AK3

211

Q9NZJ5
SYRSRINEKSVWCCG

ASB1

61

Q9Y576
RTYRWQCIECKSCSL

DPF1

316

Q92782
LTVWACQGRQCSYRK

ACVR1C

131

Q8NER5
RCKTRDRQCKYIWGQ

ADAM22

546

Q9P0K1
CRRITWGKYMNCGQT

ALDH3A2

226

P51648
NYQWLCTRLNGKCKT

DMD

1246

P11532
LCRQIRAACVIQSYW

ASPM

1556

Q8IZT6
SYNRNWRVCALLSCT

AKR1B1

291

P15121
YCLSCIRQWRCAKQF

MKRN2

266

Q9H000
SVKRNQAVWSCSGCF

NFXL1

166

Q6ZNB6
QRCFSSKVCVRSRCW

NADK2

391

Q4G0N4
RVFCWRSVNSSLKQC

IBTK

416

Q9P2D0
QFACRDQITCISKGW

LRP1

31

Q07954
WYVAACRANVKSGAI

PPFIA3

856

O75145
LQCFCKYLQRWREAV

MCM3AP

1236

O60318
CQAEGPRAYKRWVCS

EFNA4

86

P52798
RWIDYGKVATQCTCR

KDM4B

296

O94953
WYVAACRANVKSGAI

PPFIA1

896

Q13136
RCAVRATNNCKWTTL

DGKH

216

Q86XP1
NDVTYRILCKRCSWE

EPHA7

361

Q15375
WLNKSECRNINRTYC

IL20RA

81

Q9UHF4
WEKQIYTCCRDGLVR

PAAF1

371

Q9BRP4
VALCTKGGYWRRAQC

PRG3

201

Q9Y2Y8
WVYACGQTQSRKLCS

MALRD1

421

Q5VYJ5
TWQSLCYRKIAAGRA

FZD9

536

O00144
LVAGKTYRWCVCGRS

CISD3

51

P0C7P0
QKIFASCWRLQGTCR

DEFB135

31

Q30KP9
RCWKGQGACQTYCTR

DEFB124

26

Q8NES8
CQWKNRIVACQAFSR

HEATR4

641

Q86WZ0
QTICVRFWRCSNSKK

PRMT5

596

O14744
IQTATWLKCVCYQRV

MBOAT1

351

Q6ZNC8
CQSRGRCINLWLSYQ

CRB1

681

P82279
VSFIDQRRWKCNLCY

SEC24B

616

O95487
QRRWKCNLCYRVNDV

SEC24B

621

O95487
WYCLNTNTHGCRRIV

SCNN1G

31

P51170
WYVAACRANVKSGAI

PPFIA2

916

O75334
RSLQGWVCYVTFICN

MIF4GD

96

A9UHW6
WDYIRVACRKVSQNC

RUNDC3B

111

Q96NL0
RNACTAVCFWRSKVV

RTN4IP1

11

Q8WWV3
GCWCYLRLQRISQSE

SNN

31

O75324
CQQVASFCRGYWLSL

ABCC6

956

O95255
LRWCYLQVAIVGTCA

SLC22A9

176

Q8IVM8
RIKCVTRIQAYWRGC

RNF32

186

Q9H0A6
RWKLTCYICKQRGSG

BRPF1

381

P55201
QRTVRKVAWSPCGNY

CIAO1

61

O76071
KGWGQCYTRQFISSC

SMAD7

401

O15105
RITNWNRKLGCKCQY

XYLT1

551

Q86Y38
VARRCWSGNQKAYEI

UROC1

631

Q96N76
CAWCQKVGIKRYSLS

SOBP

151

A7XYQ1
KAVNTARGLYQRWCE

STX10

16

O60499
KIWDVNSERCRCTLY

SPAG16

461

Q8N0X2
YNIWCNVRGKTASRQ

AVPR1A

241

P37288
WCNLRSGSERKQLCT

TNFRSF4

86

P43489
GCNRQSWCLKRYDLE

TRIM14

356

Q14142
QYHRNGCISIWRKIC

SLC6A4

141

P31645
LTCCGRDQVCYRWSK

PLD2

221

O14939
YLTDTQCKRVGTQCW

PTDSS1

341

P48651
VTYCSSCKLIQCWGQ

TMC7

521

Q7Z402
IWGLARQGYRCINCK

PRKCZ

151

Q05513