Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

2.50e-07382337GO:0000146
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B DYNC1H1 KIF16B

1.02e-051182339GO:0003774
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 MYH2 MYH3 MYH4 MYH11 ERCC6 MYH13 MYO5B ABCA13 ABCB4 UBA1 ATAD2B CHD6 ABCC2 DDX11L8 DYNC1H1 KIF16B NLRP1 KATNA1 NLRP10 MACF1

1.14e-0561423321GO:0140657
GeneOntologyMolecularFunctionactin filament binding

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B ACTN1 FERMT2 CAPZA1 MACF1 NEXN

1.54e-0522723312GO:0051015
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH3 MYH4 ERCC6 MYO5B ABCA13 ABCB4 ATAD2B CHD6 ABCC2 DDX11L8 DYNC1H1 KIF16B NLRP1 KATNA1 NLRP10 MACF1

6.55e-0544123316GO:0016887
GeneOntologyMolecularFunctioncytoskeletal protein binding

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B EML6 ACTN1 ADGRV1 STX1A KCNE1 SYNE2 MTCL1 FERMT2 ANK3 CAPZA1 KIF16B TRIM54 KATNA1 TRIM32 TTLL4 MACF1 MAPK8 NEXN EPB41L1 CHP1

2.12e-04109923327GO:0008092
GeneOntologyMolecularFunctionphosphatidylinositol phosphate 5-phosphatase activity

INPP5D SYNJ2 PIKFYVE

4.11e-04132333GO:0034595
GeneOntologyBiologicalProcessregulation of protein targeting to membrane

PDZK1 KCNE1 MTCL1 TENT2 ANK3 CHP1

7.78e-06432306GO:0090313
GeneOntologyBiologicalProcessregulation of protein targeting

PDZK1 SREBF1 KCNE1 MTCL1 TENT2 ANK3 HUWE1 CHP1

9.55e-06932308GO:1903533
GeneOntologyBiologicalProcesspositive regulation of protein targeting to membrane

PDZK1 MTCL1 TENT2 ANK3 CHP1

4.08e-05352305GO:0090314
GeneOntologyCellularComponentmyosin filament

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 TRIM32

8.15e-09252347GO:0032982
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

1.35e-08162346GO:0005859
GeneOntologyCellularComponentmyosin complex

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B CGNL1

2.97e-07592348GO:0016459
GeneOntologyCellularComponentmyosin II complex

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

5.66e-07282346GO:0016460
GeneOntologyCellularComponentcontractile muscle fiber

MYH1 MYH2 MYH3 MYH4 MYH11 IGFN1 MYH13 ACTN1 KCNE1 SYNE2 FERMT2 ANK3 TRIM54 TRIM32 NEXN

1.04e-0629023415GO:0043292
GeneOntologyCellularComponentactin cytoskeleton

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B INPP5D DGKH ACTN1 STX1A AMOT FERMT2 TNS3 CAPZA1 ZNF74 MACF1 PRKCZ CGNL1 MAPK8 NEXN

2.29e-0657623421GO:0015629
GeneOntologyCellularComponentmyofibril

MYH1 MYH2 MYH3 MYH4 IGFN1 MYH13 ACTN1 KCNE1 SYNE2 FERMT2 ANK3 TRIM54 TRIM32 NEXN

2.65e-0627323414GO:0030016
GeneOntologyCellularComponentsarcomere

MYH1 MYH2 MYH3 MYH4 IGFN1 ACTN1 KCNE1 SYNE2 FERMT2 ANK3 TRIM54 TRIM32 NEXN

5.00e-0624923413GO:0030017
GeneOntologyCellularComponentcell-cell junction

MYH1 MYH2 EPPK1 PAK4 ADGRB1 ACTN1 ABCB4 UBA1 AMOT ABCC2 FERMT2 ANK3 CAPZA1 PIKFYVE FRMD4A PAK2 PRKCZ CGNL1 NEXN

4.02e-0559123419GO:0005911
GeneOntologyCellularComponentsupramolecular fiber

MYH1 MYH2 MYH3 MYH4 MYH11 IGFN1 EPPK1 MYH13 INPP5D EML6 ACTN1 SYNJ2 KCNE1 AMOT SYNE2 MTCL1 FERMT2 DYNC1H1 ANK3 KIF16B TRIM54 KATNA1 TRIM32 TTLL4 GRAMD2B MACF1 NEXN PTPN20

1.43e-04117923428GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MYH1 MYH2 MYH3 MYH4 MYH11 IGFN1 EPPK1 MYH13 INPP5D EML6 ACTN1 SYNJ2 KCNE1 AMOT SYNE2 MTCL1 FERMT2 DYNC1H1 ANK3 KIF16B TRIM54 KATNA1 TRIM32 TTLL4 GRAMD2B MACF1 NEXN PTPN20

1.60e-04118723428GO:0099081
GeneOntologyCellularComponentanchoring junction

MYH1 MYH2 EPPK1 RPS4X PAK4 ADGRB1 ACTN1 ABCB4 SENP1 UBA1 AMOT SYNE2 ABCC2 FERMT2 TNS3 ANK3 CAPZA1 PIKFYVE FRMD4A PAK2 PRKCZ CGNL1 NEXN CHP1

2.64e-0497623424GO:0070161
GeneOntologyCellularComponentsymmetric synapse

PENK MKLN1 SLC4A8

3.65e-04132343GO:0032280
GeneOntologyCellularComponentI band

IGFN1 ACTN1 KCNE1 SYNE2 FERMT2 ANK3 TRIM54 NEXN

5.79e-041662348GO:0031674
GeneOntologyCellularComponentneuron to neuron synapse

ASIC2 PENK ADGRB1 DNAJC6 STX1A MIB1 MKLN1 DNAJB1 SLC4A8 ANK3 PAK2 MACF1 TANC1 PRKCZ EPB41L1

8.59e-0452323415GO:0098984
GeneOntologyCellularComponentcluster of actin-based cell projections

MINAR2 MYH11 MYO5B PDZK1 ACTN1 ADGRV1 ABCC2 CAPZA1 ANKRD24

9.54e-042232349GO:0098862
GeneOntologyCellularComponentperinucleolar compartment

EPPK1 PDCL3

1.22e-0352342GO:0097356
GeneOntologyCellularComponentdense core granule lumen

PENK VPS13A

1.22e-0352342GO:0098898
GeneOntologyCellularComponentneuronal dense core vesicle lumen

PENK VPS13A

1.22e-0352342GO:0099013
GeneOntologyCellularComponentZ disc

IGFN1 ACTN1 KCNE1 SYNE2 ANK3 TRIM54 NEXN

1.59e-031512347GO:0030018
GeneOntologyCellularComponentpostsynaptic specialization

ASIC2 ADGRB1 DNAJC6 CHRNE STX1A MIB1 MKLN1 DNAJB1 ANK3 PAK2 MACF1 TANC1 PRKCZ EPB41L1

1.68e-0350323414GO:0099572
GeneOntologyCellularComponentactomyosin

MYH11 ACTN1 STX1A AMOT FERMT2 PRKCZ

2.05e-031172346GO:0042641
HumanPhenoAbnormal toe epiphysis morphology

TBC1D2B EIF2AK3 ARSL

4.17e-063833HP:0010160
DomainMyosin_tail_1

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 CGNL1

1.08e-09182297PF01576
DomainMyosin_tail

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 CGNL1

1.08e-09182297IPR002928
DomainMyosin_N

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

1.45e-08152296PF02736
DomainMyosin_N

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

1.45e-08152296IPR004009
DomainMyosin-like_IQ_dom

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

7.56e-08192296IPR027401
Domain-

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

7.56e-081922964.10.270.10
DomainMyosin_head_motor_dom

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

3.47e-07382297IPR001609
DomainMYOSIN_MOTOR

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

3.47e-07382297PS51456
DomainMyosin_head

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

3.47e-07382297PF00063
DomainMYSc

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

3.47e-07382297SM00242
DomainIQ

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

2.60e-05712297PF00612
DomainPAK_BD

PAK4 PAK5 PAK2

3.54e-0562293IPR033923
DomainIQ

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

6.12e-05812297SM00015
DomainWASP_C

PAK4 PAK5 PAK2

6.14e-0572293IPR011026
DomainAnk_2

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

7.27e-0521522911PF12796
Domain-

ARHGAP15 NET1 TBC1D2B DGKH AGAP11 ARHGEF11 PLEKHG1 OSBPL9 FERMT2 TNS3 DGKD RGS12 FRMD4A EPB41L1 FAM43A

1.02e-04391229152.30.29.30
DomainIQ_motif_EF-hand-BS

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

1.20e-04902297IPR000048
DomainIQ

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

1.47e-04932297PS50096
DomainGolgin_subfamily_A_member_5

GOLGA5 VIPAS39

1.50e-0422292IPR019177
DomainCCDC74

CCDC74B CCDC74A

1.50e-0422292IPR033226
DomainCCDC74_C

CCDC74B CCDC74A

1.50e-0422292IPR029422
DomainCCDC74_C

CCDC74B CCDC74A

1.50e-0422292PF14917
DomainGolgin_A5

GOLGA5 VIPAS39

1.50e-0422292PF09787
Domain-

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

2.55e-04248229111.25.40.20
DomainPH_dom-like

ARHGAP15 NET1 TBC1D2B DGKH AGAP11 ARHGEF11 PLEKHG1 OSBPL9 FERMT2 TNS3 DGKD RGS12 FRMD4A EPB41L1 FAM43A

2.60e-0442622915IPR011993
DomainANK

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

2.83e-0425122911SM00248
DomainANK_REPEAT

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

3.02e-0425322911PS50088
DomainAnkyrin_rpt-contain_dom

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

3.13e-0425422911IPR020683
DomainANK_REP_REGION

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

3.13e-0425422911PS50297
Domain-

PAK4 PAK5 PAK2

3.69e-041222933.90.810.10
DomainAnkyrin_rpt

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

4.07e-0426222911IPR002110
DomainAnk

ANKRD31 ANKRD30B AGAP11 MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

5.29e-0422822910PF00023
DomainGPS

ADGRB1 ADGRV1 PKDREJ ADGRG3

7.65e-04342294SM00303
DomainPBD

PAK4 PAK5 PAK2

9.05e-04162293SM00285
DomainGPS

ADGRB1 ADGRV1 PKDREJ ADGRG3

1.06e-03372294IPR000203
DomainPBD

PAK4 PAK5 PAK2

1.09e-03172293PF00786
PathwayKEGG_TIGHT_JUNCTION

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 ACTN1 PRKCZ EPB41L1

2.58e-051321669M11355
PathwaySIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES

MYH2 RPS4X PAK4 PAK5 PAK2

5.20e-05351665M16801
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

GAPVD1 ARHGAP15 NET1 CNST PAK4 SPCS2 WDR75 AMOT POP1 ARID5B MKLN1 PAN2 ANKRD12 CPLANE1 FERMT2 PLXNB1 ANK3 APOB HUWE1 SLC39A10 FAM171B GPATCH2L PACS1 ZNF750 ZNF182 TCP11L2 TTLL4 GRAMD2B LTN1 OGDHL MACF1 PRKCZ NEXN

8.14e-1310842383311544199
Pubmed

A human MAP kinase interactome.

MYH11 ZNF142 PAK4 ACTN1 ARHGEF11 FAM13B SYNJ2 CHD6 NKTR CPLANE1 VRK2 ANK3 PAK5 ADNP2 MAPKAPK5 PAK2 MACF1 ANKRD24 PRKCZ CGNL1 MAP3K21

2.87e-114862382120936779
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH1 MYH2 MYH3 MYH4 MYH13

8.59e-116238510077619
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TET2 GAPVD1 BCLAF1 PAK4 SPCS2 TBC1D2B AGAP11 ADGRV1 SULF2 SYNJ2 ZC3H4 AMOT MIB1 PAN2 CRAMP1 PLXNB1 KIF16B DZIP1 GPATCH2L IVNS1ABP TTLL4

1.36e-105292382114621295
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH1 MYH2 MYH3 MYH4 MYH13

2.99e-107238535210422
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

CDKAL1 LRIG2 SYNE2 KXD1 VPS13A OSBPL9 CKAP4 GOLGA5 EIF2AK3 TRAPPC2 FNIP2 DMXL2 VRK2 KIF16B TMEM43 HS1BP3 SLC39A10 PIKFYVE VIPAS39 CHP1

3.84e-105042382034432599
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 GAPVD1 PDE3B NET1 PAK4 EDC4 PLEKHG1 SYNJ2 AMOT RAB3GAP2 SYNE2 MTCL1 TNS3 DNAJB1 PAK5 DZIP1 HDAC7 RGS12 IVNS1ABP MACF1 TANC1 CGNL1 MAP3K21 EPB41L1 DOP1A

1.54e-098612382536931259
Pubmed

Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

MYH1 MYH2 MYH4 MYH13

2.14e-094238410388558
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PDE3B PDE9A DGKH FOXN3 ADGRV1 TRRAP CASZ1 GMPS SENP1 SYNJ2 ANKAR ARID5B MKLN1 OSBPL9 KATNIP CHD6 ANKRD12 HSD11B2 CRAMP1 ANK3 CAPZA1 HUWE1 PACS1 EFNA1 SUGP2 ZNF827 TLL1 MACF1 ANKRD24 TANC1 PRKCZ EPB41L1 DOP1A

3.02e-0914892383328611215
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B BCLAF1 RPS4X ADAM7 EML6 ANKRD30B ACTN1 ABCB4 WDR75 GCLC SYNE2 VPS13A CHD6 ABCC2 TRAPPC2 PTBP3 CAPZA1 REL APOB XPC TMEM43 SBNO1 OGDHL MACF1 DOP1A ATPAF2

5.22e-0914422383235575683
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MYH1 MYH3 MYH4 GAPVD1 PDE3B TOPAZ1 ADGRB1 DGKH GMPS AMOT ATAD2B POP1 VPS13A ARID5B CHD6 MTCL1 ALOX5 DYNC1H1 TNPO2 HUWE1 IVNS1ABP TNFSF11

9.29e-097362382229676528
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH1 MYH2 MYH3 MYH4

1.06e-08523843829126
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH1 MYH2 MYH3 MYH4

1.06e-08523846196357
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYO5B PAK4 GMPS UBA1 SYNE2 PPM1L MIB1 VPS13A CKAP4 GOLGA5 TNS3 DNAJB1 VRK2 ANK3 HUWE1 SLC39A10 FAM171B FAN1 PACS1 VIPAS39 PRIM2 LTN1 TANC1 MAPK8 PTPN20 EPB41L1

1.83e-0810492382627880917
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TET2 PDE9A CNST USP25 ACTN1 ZNF619 HUNK CUEDC1 STX1A MIB1 ARID5B MKLN1 CCDC15 CHD6 DYNC1H1 DMXL2 ANK3 TNPO2 ADNP2 XPC DZIP1 HUWE1 FAN1 EFNA1 SBNO1 TRIM32 PAK2 MACF1 ANKRD24

2.03e-0812852382935914814
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

PDE3B SPCS2 CDKAL1 LRIG2 SENP1 RAB3GAP2 SYNE2 VPS13A CKAP4 GOLGA5 EIF2AK3 VRK2 KIF16B TMEM43 SLC39A10 GRAMD2B CHP1

3.03e-084682381731056421
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH1 MYH2 MYH3 MYH4

3.17e-08623841728586
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH1 MYH2 MYH3 MYH4

3.17e-086238410588881
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MYH11 MYO5B CASZ1 LRIG2 POP1 DMXL2 SLC4A8 DGKD DENND3 FAN1 PIKFYVE LTN1 MACF1 ANKRD24 CGNL1 PRDM16 DOP1A

6.40e-084932381715368895
Pubmed

ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.

MYH1 MYH2 MYH3 MYH4

7.36e-087238429758057
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH1 MYH2 MYH3 MYH4

7.36e-087238416819597
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

PDZK1 PAK4 ABCC2 GOLGA5 FERMT2 PLXNB1 TNS3 SLC4A8 KIF16B APOB SLC39A10 RGS12 PACS1 FRMD4A GRAMD2B TANC1 EPB41L1 CHP1

9.45e-085692381830639242
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PDE3B BCLAF1 PAK4 DNAJC6 CDKAL1 LRIG2 PLEKHG1 SENP1 WDR75 RAB3GAP2 SYNE2 POP1 MIB1 VPS13A CKAP4 GOLGA5 FERMT2 EIF2AK3 DNAJB1 DMXL2 VRK2 ANK3 KIF16B MRPL58 DZIP1 SLC39A10 GKAP1 MACF1 TANC1 EPB41L1

1.32e-0714872383033957083
Pubmed

Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.

MYH1 MYH2 MYH4 CHRNE

1.46e-078238426993635
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DNAJC6 KIAA0319 PLEKHG1 CRACD RAB3GAP2 KATNIP CHD6 ANKRD12 MTCL1 DYNC1H1 FNIP2 SLC39A10 SUGP2 MACF1 EPB41L1

1.67e-074072381512693553
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH2 MYH4

3.16e-073238326059207
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

SPCS2 CDKAL1 VPS13A CKAP4 EIF2AK3 VRK2 TMEM43 SLC39A10 GRAMD2B CHP1

4.19e-071762381028692057
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

GAPVD1 BCLAF1 RPS4X PAK4 CDKAL1 GMPS UBA1 RAB3GAP2 CKAP4 FERMT2 EIF2AK3 DYNC1H1 DNAJB1 ANK3 CAPZA1 PAK2 MACF1 MAP3K21 EPB41L1

5.11e-077082381939231216
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PLEKHG1 CRACD SULF2 ATAD2B PAK5 SLC39A10 OGDHL MACF1

5.81e-07103238810574462
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ERCC6 ABCA13 BCLAF1 RPS4X ADGRB1 WDR75 GOLGA5 EIF2AK3 CAPZA1 NLRP1 DGKD APOB SLC39A10 TCP11L2 MAPK8 ATPAF2

6.00e-075132381625798074
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ARHGEF11 KIAA0319 SYNJ2 DYNC1H1 ADAMTS3 HUWE1 SUGP2 EPB41L1

6.26e-0710423889205841
Pubmed

Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.

MYH1 MYH2 MYH3 MYH4

6.80e-0711238416024798
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MYH13 BCLAF1 RPS4X GMPS SENP1 POP1 FAT3 PBRM1 MACF1 CGNL1 PRDM16

7.30e-072342381136243803
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

ANKRD31 CNST ADGRV1 AMOT ARID5B DENND3 MACF1 CGNL1 MAP3K21

1.14e-06152238934299191
Pubmed

Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.

MYH1 MYH2 MYH3

1.26e-064238320357587
Pubmed

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

MYH1 MYH3 MYH4

1.26e-06423831985022
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH1 MYH2 MYH4

1.26e-064238311029314
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH1 MYH2 MYH4

1.26e-064238318417546
Pubmed

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.

MYH1 MYH2 MYH4

1.26e-064238311023856
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH1 MYH2 MYH3 GAPVD1 MYH13 BCLAF1 PAK4 TRRAP ZC3H4 NKTR CPLANE1 ANAPC5 TNS3 TRAF7 PAK5 MAPKAPK5 GPATCH2L EFNA1 MAPK8 MAP3K21 CDK2

1.44e-069102382136736316
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

GAPVD1 BCLAF1 ACTN1 EDC4 TRRAP UBA1 AMOT RAB3GAP2 OSBPL9 DYNC1H1 DNAJB1 ANK3 CAPZA1 HUWE1 SUGP2 PAK2

1.45e-065492381638280479
Pubmed

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

MYH1 MYH2 MYH3 MYH4

1.46e-061323848404542
Pubmed

The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.

MYH1 MYH2 MYH3 PRKCZ

1.46e-061323848948582
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

NET1 CRACD ZC3H4 POP1 ARID5B OSBPL9 CHD6 FERMT2 KIF16B EFNA1 PBRM1 OGDHL CDK2

1.55e-063632381314691545
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

MINAR2 PDZK1 ADGRB1 AGAP11 EDC4 SULT1C4 TRRAP CDKAL1 PLEKHG1 SYNJ2 GCLC GLDC VPS13A OSBPL9 FNIP2 DMXL2 ADAMTS3 SYT16 ZNF182 EFNA1 TTLL4 PRKCZ RUNDC1 RAPGEFL1 ATPAF2

1.65e-0612422382530973865
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MYH2 MYH4 NET1 ADGRB1 USP25 TRRAP GMPS WDR75 GLDC AMOT OSBPL9 PAN2 MTCL1 CKAP4 TRAPPC2 DNAJB1 CAPZA1 HUWE1 IVNS1ABP FARS2 PRIM2 ELL

1.89e-0610052382219615732
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

GAPVD1 MYH13 BCLAF1 LRIG2 ZC3H4 AMOT VPS13A OSBPL9 GOLGA5 FERMT2 DYNC1H1 ANK3 APOB HUWE1 SLC39A10 FAM171B VIPAS39 SUGP2 CGNL1

2.02e-067772381935844135
Pubmed

Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.

MYH1 MYH2 MYH3 MYH4

2.03e-0614238427184118
Pubmed

Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.

MYH1 MYH2 MYH4 ACTN1

2.03e-0614238424938781
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

RPS4X EDC4 GMPS CRACD RAB3GAP2 SYNE2 CKAP4 FERMT2 DNAJB1 DMXL2 TNPO2 PBRM1 SUGP2 MACF1 EPB41L1

2.08e-064982381536634849
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

GAPVD1 SPCS2 CDKAL1 RAB3GAP2 SYNE2 VPS13A OSBPL9 CKAP4 GOLGA5 FERMT2 EIF2AK3 DNAJB1 VRK2 TANC1 CDK2 CHP1

2.25e-065682381637774976
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPPK1 SREBF1 EDC4 ARHGEF11 TRRAP CASZ1 PLEKHG1 ALOX5 CRAMP1 DYNC1H1 TRAF7 HUWE1 MAPKAPK5 HDAC7 PIKFYVE SUGP2 ZNF827 TTLL4 OGDHL TANC1 PRDM16 ELL ATPAF2

2.54e-0611052382335748872
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

SREBF1 ACTN1 UBA1 RAB3GAP2 SYNE2 ANKRD12 DYNC1H1 DMXL2 RGS12 MACF1 PRKCZ HTR3B

2.61e-063222381226514267
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH1 MYH2 MYH3 MYH4 MYH11 EPPK1 MYH13 ACTN1 UBA1 RAB3GAP2 DYNC1H1 TNS3 DNAJB1 CAPZA1 HUWE1 TRIM32 LTN1

2.75e-066472381726618866
Pubmed

Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.

MYH1 MYH2 MYH3 MYH4

2.75e-0615238424852826
Pubmed

Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.

MYH1 MYH2 MYH3

3.13e-06523836879174
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH1 MYH2 MYH4

3.13e-065238312919077
Pubmed

Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.

MYH1 MYH2 MYH4

3.13e-065238330737693
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

BCLAF1 EDC4 ARHGEF11 DNAJC6 KIAA0319 LRIG2 SENP1 UBA1 ZC3H4 SYNE2 MTCL1 DYNC1H1 DMXL2 SLC4A8 ANK3 PAK5 HUWE1 PBRM1 PAK2 MACF1 EPB41L1

3.48e-069632382128671696
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ADGRV1 SULF2 ZC3H4 AMOT RAB3GAP2 SYNE2 CHD6 DMXL2 MACF1 PRDM16

3.87e-062252381012168954
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

CNST BCLAF1 RPS4X ADGRB1 EDC4 GMPS STX1A UBA1 RAB3GAP2 MKLN1 CKAP4 FERMT2 DMXL2 SLC4A8 ANK3 TMEM43 HUWE1 FAM171B FRMD4A VIPAS39 SUGP2 MACF1 EPB41L1

4.19e-0611392382336417873
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

GAPVD1 PDE9A NET1 MYO5B PAK4 ACTN1 UBA1 AMOT MKLN1 PAN2 KATNIP NKTR GOLGA5 FERMT2 DYNC1H1 DNAJB1 ANK3 CAPZA1 HDAC7 IVNS1ABP PACS1 SBNO1 TRIM32 GKAP1 MAP3K21

4.87e-0613212382527173435
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYH11 RAB3GAP2 ANKRD12 DMXL2 ADNP2 DENND3 IVNS1ABP

6.00e-06100238710048485
Pubmed

A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.

MYH1 MYH2 MYH4

6.23e-066238320417199
Pubmed

Targeted disruption of the gene for the PAK5 kinase in mice.

PAK4 PAK5 PAK2

6.23e-066238314517284
Pubmed

A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.

MYH1 MYH2 MYH4

6.23e-066238317559643
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ERCC6 RPS4X ACTN1 TRRAP GMPS UBA1 WDR75 POP1 MIB1 CKAP4 FERMT2 DYNC1H1 TNS3 CAPZA1 ADNP2 DGKD XPC HUWE1 SUGP2 TRIM32 PRIM2 LTN1 MACF1 TANC1 NEXN

7.34e-0613532382529467282
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH3 ZNF619 AMOT SYNE2 MKLN1 TRAPPC2 DMXL2 TRIM54 DGKD DZIP1 GPATCH2L IVNS1ABP TRIM32 MACF1

9.77e-064972381423414517
Pubmed

Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling.

PAK4 PAK2 PRKCZ

1.09e-057238318319301
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

BCLAF1 PAK4 UBA1 SYNJ2 ZC3H4 AMOT CKAP4 FERMT2 TNS3 PTBP3 DNAJB1 CAPZA1 XPC SUGP2 GKAP1 PAK2 MACF1

1.19e-057242381736232890
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GAPVD1 EPPK1 RPS4X ACTN1 EDC4 TRRAP GMPS WDR75 ATAD2B SYNE2 POP1 DYNC1H1 HUWE1 PBRM1 SUGP2 MACF1

1.29e-056532381622586326
Pubmed

BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.

RPS4X EDC4 GMPS CKAP4 TNS3 DNAJB1 CAPZA1 TANC1

1.30e-05156238832850835
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PDE3B DGKH CDKAL1 SENP1 WDR75 ZC3H4 RAB3GAP2 PDCL3 SYNE2 MIB1 VPS13A OSBPL9 CKAP4 GOLGA5 EIF2AK3 PTBP3 VRK2 KIF16B MRPL58 HUWE1 PIKFYVE VIPAS39 OGDHL TANC1 CHP1 ATPAF2

1.39e-0514962382632877691
Pubmed

A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.

MYH1 MYH2 MYH3 MYH4

1.42e-0522238424301466
Pubmed

Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development.

MYH1 MYH2 MYH4

1.73e-058238333667029
Pubmed

A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.

MYH1 MYH2 MYH4

1.73e-058238314667415
Pubmed

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

MYH1 MYH3 MYH4

1.73e-05823833864153
Pubmed

Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex.

MYH1 MYH3 MYH4

1.73e-058238336200826
Pubmed

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.

ABCB4 ABCC2 NR1H4

1.73e-058238311279518
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

SREBF1 ABCB4 ABCC2 NR1H4 APOB

1.75e-0547238511208732
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH11 MYO5B BCLAF1 RPS4X ACTN1 EDC4 ARHGEF11 DNAJC6 CRACD UBA1 AMOT OSBPL9 FERMT2 DYNC1H1 DMXL2 ANK3 CAPZA1 PACS1 SUGP2 GKAP1 OGDHL MACF1 TANC1 CGNL1 EPB41L1

1.89e-0514312382537142655
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

TET2 CASZ1 GMPS SALL1 SYNE2 ARID5B TNPO2 ADNP2 NLRP1 PBRM1 PRDM16 CDK2

2.19e-053982381235016035
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

GAPVD1 MYO5B ACTN1 GMPS UBA1 RAB3GAP2 POP1 FERMT2 CAPZA1 HUWE1 HDAC7 CGNL1

2.30e-054002381235013556
Pubmed

GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.

MYH1 MYH2 MYH4

2.58e-059238331960486
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

GAPVD1 EPPK1 MYO5B BCLAF1 RPS4X ACTN1 EDC4 TRRAP UBA1 WDR75 ZC3H4 AMOT SYNE2 CKAP4 DYNC1H1 CAPZA1 HUWE1 PBRM1 SUGP2 MACF1

2.91e-0510242382024711643
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF142 SYNE2 ADNP2 HUWE1 FRMD4A TANC1

3.07e-0587238612465718
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ERCC6 NET1 TRRAP CDKAL1 SENP1 SULF2 ZC3H4 CKAP4 ANAPC5 TENT2 TRAF7 FAT3 ADNP2 XPC PBRM1 SUGP2 ZNF827 LTN1 MACF1 TANC1 PRDM16

3.14e-0511162382131753913
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

TET2 MYO5B ARHGEF11 KIAA0319 SYNJ2 KATNIP MACF1

3.33e-05130238712421765
Pubmed

Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.

MYH1 MYH2 MYH3

3.66e-051023838950513
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MYH2 ZNF142 CASZ1 SALL1 WDR75 SYNE2 MIB1 VPS13A ARID5B CHD6 MTCL1 KIF16B XPC RAD51AP2 PBRM1

3.86e-056382381531182584
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ABCA13 BCLAF1 PDCL3 MTCL1 CPLANE1 TNS3 ANK3 KATNA1 MACF1 MAP3K21 FAM43A

4.39e-053612381126167880
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

PDE3B CDKAL1 RAB3GAP2 SYNE2 MIB1 VPS13A CKAP4 EIF2AK3 VRK2 CHP1

4.50e-052992381037931956
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SPCS2 SREBF1 EDC4 TRRAP GMPS CRACD UBA1 SALL1 GCLC RAB3GAP2 MIB1 ARID5B NKTR CRAMP1 KATNA1 MAPKAPK5 PBRM1 SBNO1 PAK2 RUNDC1 ELL CDK2 CHP1

4.66e-0513272382332694731
Pubmed

Response to Gerlic et al.

SREBF1 NLRP1

4.66e-052238224606892
Pubmed

NLRP1a expression in Srebp-1a-deficient mice.

SREBF1 NLRP1

4.66e-052238224606891
Pubmed

Myosin heavy chains IIa and IId are functionally distinct in the mouse.

MYH1 MYH2

4.66e-05223829585413
Pubmed

Identification and characterization of two splice variants of human diacylglycerol kinase eta.

DGKH DGKD

4.66e-052238212810723
Pubmed

CDK2-activated TRIM32 phosphorylation and nuclear translocation promotes radioresistance in triple-negative breast cancer.

TRIM32 CDK2

4.66e-052238237734566
Pubmed

Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice.

ERCC6 XPC

4.66e-052238210850428
Pubmed

Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting.

MYH1 MYH2

4.66e-052238216575183
InteractionYWHAH interactions

TET2 GAPVD1 PDE3B MYH11 EPPK1 NET1 PAK4 EDC4 PLEKHG1 UBA1 SYNJ2 AMOT RAB3GAP2 SYNE2 NKTR MTCL1 FERMT2 TNS3 TRAPPC2 DNAJB1 PAK5 DZIP1 HUWE1 HDAC7 RGS12 IVNS1ABP PACS1 FRMD4A SNCAIP TRIM32 PAK2 MACF1 TANC1 PRKCZ CGNL1 MAP3K21 EPB41L1 DOP1A CDK2

5.02e-10110223539int:YWHAH
InteractionYWHAG interactions

TET2 GAPVD1 PDE3B NET1 BCLAF1 PAK4 EDC4 TRRAP FAM13B PLEKHG1 CRACD UBA1 SYNJ2 AMOT SYNE2 NKTR MTCL1 DYNC1H1 TNS3 TRAPPC2 DNAJB1 PAK5 DZIP1 HUWE1 MAPKAPK5 HDAC7 RGS12 PACS1 FRMD4A TRIM32 PAK2 MACF1 TANC1 PRKCZ CGNL1 MAP3K21 EPB41L1 DOP1A CDK2

1.62e-08124823539int:YWHAG
InteractionRAB35 interactions

GAPVD1 PDE3B PAK4 TBC1D2B CDKAL1 AMOT SYNE2 VPS13A OSBPL9 CKAP4 GOLGA5 FERMT2 EIF2AK3 DNAJB1 VRK2 ANK3 TRIM54 DZIP1 SLC39A10 MACF1 TANC1 MAP3K21 EPB41L1

2.80e-0757323523int:RAB35
InteractionGJA1 interactions

CNST PAK4 TBC1D2B ACTN1 CDKAL1 SYNE2 MIB1 VPS13A CKAP4 GOLGA5 FERMT2 EIF2AK3 VRK2 ANK3 KIF16B APOB DZIP1 SLC39A10 FAM171B MACF1 TANC1 EPB41L1

1.43e-0658323522int:GJA1
InteractionOTULINL interactions

PDE3B SPCS2 CDKAL1 LRIG2 SENP1 RAB3GAP2 SYNE2 VPS13A CKAP4 GOLGA5 EIF2AK3 VRK2 KIF16B TMEM43 SLC39A10 GRAMD2B CHP1

5.92e-0640523517int:OTULINL
InteractionRAC1 interactions

ARHGAP15 MYO5B RPS4X PAK4 TBC1D2B ARHGEF11 FAM13B PLEKHG1 SENP1 SYNJ2 VPS13A CKAP4 FERMT2 PLXNB1 TNS3 TRAF7 VRK2 ANK3 PAK5 HUWE1 SLC39A10 FAM171B HDAC7 PIKFYVE PACS1 PAK2 MACF1 TANC1 EPB41L1 CDK2

6.89e-06106323530int:RAC1
InteractionYWHAZ interactions

TET2 GAPVD1 PDE3B MYH11 PAK4 FAM13B CRACD UBA1 SYNE2 KATNIP FERMT2 DYNC1H1 TRAPPC2 DMXL2 PAK5 DZIP1 HUWE1 MAPKAPK5 HDAC7 RGS12 FAN1 IVNS1ABP PACS1 TRIM32 PAK2 MACF1 TANC1 PRKCZ CGNL1 MAPK8 MAP3K21 RUNDC1 EPB41L1 CDK2

1.11e-05131923534int:YWHAZ
InteractionRAC2 interactions

PDE3B PAK4 SPCS2 TRRAP CDKAL1 SENP1 UBA1 SYNE2 VPS13A OSBPL9 CKAP4 GOLGA5 FERMT2 EIF2AK3 TNS3 TRAF7 VRK2 SLC39A10 HDAC7 PAK2 MACF1 EPB41L1

1.44e-0567423522int:RAC2
InteractionTMT1A interactions

PDE3B SPCS2 CDKAL1 LRIG2 SENP1 RAB3GAP2 SYNE2 MIB1 VPS13A OSBPL9 CKAP4 GOLGA5 EIF2AK3 VRK2 KIF16B

2.23e-0535923515int:TMT1A
InteractionRHOA interactions

PDE3B EPPK1 NET1 SPCS2 DGKH ARHGEF11 TRRAP CDKAL1 SENP1 UBA1 SYNE2 VPS13A CKAP4 GOLGA5 FERMT2 EIF2AK3 PLXNB1 TRAF7 VRK2 ANK3 DGKD SLC39A10 FAM171B HDAC7 GRAMD2B PAK2 MACF1 PRKCZ MAPK8 EPB41L1 CHP1

2.67e-05119923531int:RHOA
InteractionASAH2 interactions

MYH1 MYH3 MYH4

3.05e-0562353int:ASAH2
InteractionEPB41L4A interactions

EPPK1 MIB1 FERMT2 ANK3 SLC39A10 FAM171B MAPKAPK5 MACF1 EPB41L1

3.99e-051402359int:EPB41L4A
InteractionRAC3 interactions

PAK4 TBC1D2B CDKAL1 SENP1 SYNJ2 VPS13A CKAP4 GOLGA5 FERMT2 EIF2AK3 VRK2 SLC39A10 FAM171B HDAC7 PAK2 MACF1 TANC1 MAP3K21 EPB41L1 DOP1A

4.13e-0561923520int:RAC3
InteractionSOX7 interactions

TET2 CASZ1 SALL1 ARID5B ADNP2 PBRM1 PRDM16

4.85e-05822357int:SOX7
InteractionYWHAB interactions

TET2 GAPVD1 PDE3B PAK4 TRRAP SYNJ2 AMOT MTCL1 DYNC1H1 TNS3 TRAPPC2 PAK5 CAPZA1 DZIP1 HDAC7 RGS12 IVNS1ABP VIPAS39 TRIM32 PAK2 MACF1 TANC1 PRKCZ CGNL1 MAPK8 MAP3K21 EPB41L1

5.61e-05101423527int:YWHAB
InteractionYWHAE interactions

TET2 GAPVD1 PDE3B MYH11 PAK4 FAM13B CRACD UBA1 SYNJ2 PAN2 FERMT2 DYNC1H1 TRAPPC2 PAK5 CAPZA1 HUWE1 HDAC7 RGS12 FAN1 IVNS1ABP PACS1 ZNF750 FRMD4A TRIM32 PAK2 MACF1 TANC1 CGNL1 MAP3K21 EPB41L1 CDK2

6.38e-05125623531int:YWHAE
InteractionSEC62 interactions

PDE3B ASIC2 SPCS2 CDKAL1 LRIG2 SENP1 RAB3GAP2 SYNE2 MIB1 VPS13A OSBPL9 CKAP4 GOLGA5 EIF2AK3 VRK2 HUWE1 SLC39A10

9.87e-0550623517int:SEC62
InteractionRNF123 interactions

MYH1 MYH3 MYH4 GAPVD1 PDE3B TOPAZ1 ADGRB1 DGKH SULT1C4 GMPS AMOT ATAD2B POP1 VPS13A ARID5B CHD6 MTCL1 ALOX5 DYNC1H1 TNPO2 HUWE1 IVNS1ABP TNFSF11

1.03e-0482423523int:RNF123
GeneFamilyMyosin heavy chains

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13

2.05e-091516061098
GeneFamilyAnkyrin repeat domain containing

ANKRD31 ANKRD30B AGAP11 ANKAR MIB1 ANKRD12 ANK3 SNCAIP ASB4 ANKRD24 TANC1

1.06e-0524216011403
CoexpressionPEREZ_TP63_TARGETS

EPPK1 FOXN3 HUNK CASZ1 SYNJ2 SYNE2 HSD11B2 CRAMP1 TNPO2 NLRP1 GPATCH2L ZNF750 GKAP1 CGNL1 FAM43A

9.33e-0735623615M10761
CoexpressionGSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN

SREBF1 EDC4 TRRAP PKDREJ LRIG2 POP1 PPM1L TNS3 HS1BP3 DENND3 CGNL1

2.18e-0620023611M6585
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

NET1 BCLAF1 FAM13B CDKAL1 GMPS WDR75 MIB1 VPS13A TENT2 TRAPPC2 CAPZA1 IVNS1ABP PBRM1 LTN1 GKAP1 MAPK8 HES5

5.96e-0652323617M12707
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

NET1 BCLAF1 FAM13B CDKAL1 GMPS WDR75 MIB1 VPS13A TENT2 TRAPPC2 CAPZA1 IVNS1ABP PBRM1 LTN1 GKAP1 MAPK8 HES5

7.82e-0653423617MM1054
CoexpressionGSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP

SREBF1 ZNF215 ARHGEF11 LRIG2 SYNE2 VPS13A FRMD4A ZNF74 MACF1 DOP1A

1.28e-0519723610M8983
CoexpressionGSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

PENK ACTN1 SULF2 HS1BP3 HDAC7 DENND3 FRMD4A RAPGEFL1 FAM43A

1.33e-051572369M9117
CoexpressionPEREZ_TP53_AND_TP63_TARGETS

EPPK1 HUNK CASZ1 HSD11B2 CRAMP1 NLRP1 GPATCH2L ZNF750 CGNL1 FAM43A

1.97e-0520723610M14566
CoexpressionPEREZ_TP53_TARGETS

EPPK1 ABCA13 INPP5D EML6 ZNF215 ADGRV1 HUNK DNAJC6 CRACD GLDC MTCL1 HSD11B2 CRAMP1 FNIP2 ANK3 KIF16B NLRP1 DZIP1 GPATCH2L ZNF750 EFNA1 ZNF684 CGNL1 DOP1A FAM43A ATPAF2

3.42e-05120123626M4391
CoexpressionMURARO_PANCREAS_BETA_CELL

RPS4X EML6 SREBF1 FOXN3 DNAJC6 CRACD STX1A SYNE2 PAN2 ANKRD12 DYNC1H1 FNIP2 PTBP3 DNAJB1 DMXL2 CASR DGKD XPC HUWE1 PIKFYVE SBNO1 EPB41L1

5.01e-0594623622M39169
CoexpressionGABRIELY_MIR21_TARGETS

GAPVD1 FOXN3 RAB3GAP2 ATAD2B SYNE2 VPS13A FERMT2 EIF2AK3 TRAPPC2 PTBP3 PBRM1

6.78e-0528923611M2196
CoexpressionGSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP

ATAD2B ALOX5 KIF16B REL DGKD DENND3 PIKFYVE PAK2 MACF1

7.59e-051962369M3243
CoexpressionGSE29618_BCELL_VS_PDC_UP

ABCB4 GVINP1 ARID5B EIF2AK3 ALOX5 NLRP1 DGKD PIKFYVE MACF1

7.59e-051962369M4940
CoexpressionGSE3982_BCELL_VS_TH2_UP

MYH3 KIAA0319 GVINP1 GLDC TRAPPC2 KIF16B DGKD DENND3 ATPAF2

7.89e-051972369M5554
CoexpressionGSE8515_CTRL_VS_IL1_4H_STIM_MAC_DN

NET1 TBC1D2B DYNC1H1 PTBP3 REL MAPKAPK5 HDAC7 GRAMD2B MAPK8

7.89e-051972369M5760
CoexpressionGSE14308_TH2_VS_NAIVE_CD4_TCELL_DN

DGKH TRRAP FAM13B REL MOB3A MAPKAPK5 DENND3 SBNO1 ASB4

8.86e-052002369M3365
CoexpressionGSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN

ARHGEF11 DNAJC6 FAM13B PPM1L CHD6 EIF2AK3 TNFSF11 TRIM32 ELL

8.86e-052002369M5073
CoexpressionGSE7852_TREG_VS_TCONV_FAT_DN

MYH4 CNST TBC1D2B DNAJC6 GMPS VPS13A EIF2AK3 DGKD DZIP1

8.86e-052002369M5735
CoexpressionGSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

ARHGEF11 OSBPL9 ELAC1 ALOX5 XPC MOB3A PACS1 TCP11L2 PRKCZ

8.86e-052002369M9164
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

GAPVD1 FOXN3 TRRAP GMPS ZC3H4 ATAD2B VPS13A ARID5B MKLN1 MTCL1 FERMT2 PIKFYVE FARS2 PRIM2

9.28e-0546623614M13522
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

GAPVD1 FOXN3 TRRAP GMPS SYNJ2 ZC3H4 ATAD2B SYNE2 VPS13A ARID5B MKLN1 MTCL1 FERMT2 DMXL2 PIKFYVE FARS2 PRIM2 LTN1 MACF1 MAPK8

1.04e-0485623620M4500
CoexpressionKARLSSON_TGFB1_TARGETS_DN

NET1 TBC1D2B USP25 ACTN1 AGAP11 SYNE2 OSBPL9 SLC39A10 CHP1

1.24e-042092369MM1058
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

PDE3B ARHGAP15 DGKH SYNE2 VPS13A MKLN1 NKTR ANKRD12 ANK3 HUWE1 SLC39A10 MACF1

2.94e-1018123812f2315414e714ac86211546a935660c4be6e85f1b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B EML6 HSD11B2 PTBP3 ANK3 ADAMTS3 C4orf54 GRAMD2B ASB4 MAP3K21 PRDM16 PTPN20

3.34e-1018323812b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO5B PDZK1 HUNK GLDC SYNE2 ABCC2 NR1H4 ANK3 CASR OGDHL CGNL1 EPB41L1

4.28e-1018723812d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 DGKH ADGRV1 CASZ1 NKTR PADI1 ANK3 GRAMD2B MACF1 TANC1 RAPGEFL1

3.65e-09179238116e965e424eebef50f0202cff75f458be395cfca1
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

PDE3B BCLAF1 DGKH SYNE2 NKTR ANKRD12 EIF2AK3 DYNC1H1 REL HUWE1 MACF1

6.11e-0918823811ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DGKH LRIG2 ATAD2B SYNE2 VPS13A NKTR ANKRD12 ANK3 SNCAIP SUGP2 MACF1

8.03e-09193238119337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

HUNK CASZ1 SLC4A8 ANK3 DGKD HDAC7 FRMD4A PRIM2 TANC1 CGNL1

7.44e-0818823810b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE3B DGKH SYNE2 VPS13A ARID5B NKTR ANKRD12 ANK3 SNCAIP MACF1

1.15e-071972381057ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CWF19L2 PDE3B ATAD2B SYNE2 VPS13A NKTR ANKRD12 ANK3 SUGP2 MACF1

1.27e-0719923810f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B GLDC HSD11B2 PLXNB1 PTBP3 ADAMTS3 SYT16 OGDHL MACF1 MAP3K21

1.27e-07199238103cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TET2 MINAR2 INPP5D TBC1D2B CHD6 ALOX5 FAT3 OGDHL CGNL1

3.18e-0716823898072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B ASIC2 CASZ1 HSD11B2 ANK3 ADAMTS3 ZNF827 MAP3K21 PRDM16

5.95e-071812389aa233b652921848af2257cc3687a7a09c3acfb67
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 IVNS1ABP FRMD4A RUFY4

7.14e-071852389afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPCS2 DGKH WDR75 ATAD2B ANAPC5 ANK3 IVNS1ABP TTLL4 PRIM2

8.17e-0718823896468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPCS2 DGKH WDR75 ATAD2B ANAPC5 ANK3 IVNS1ABP TTLL4 PRIM2

8.17e-0718823897a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPCS2 DGKH WDR75 ATAD2B ANAPC5 ANK3 IVNS1ABP TTLL4 PRIM2

8.17e-0718823899cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE9A EML6 HUNK GLDC HSD11B2 NR1H4 ANK3 MAP3K21 EPB41L1

8.17e-0718823898f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B HUNK CASZ1 GLDC HSD11B2 PTBP3 ADAMTS3 MAP3K21 PRDM16

8.17e-0718823894154f4787483c7e076e87a187733a9f666742c3d
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 GLDC HSD11B2 SLC4A8 ARSL PRKCZ MAP3K21 PRDM16

8.54e-0718923895d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B EML6 HUNK CASZ1 HSD11B2 PTBP3 ADAMTS3 MAP3K21 PRDM16

8.54e-0718923898ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCelldroplet-Lung-LUNG-1m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 IVNS1ABP RUFY4 CHP1

8.54e-0718923896d24414ac6bd4f03f7a5ad3a6eba51d549a7b112
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A ASIC2 ABCA13 DGKH CASR HDAC7 IVNS1ABP SYT16 EPB41L1

8.92e-0719023893fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B HUNK CASZ1 HSD11B2 PTBP3 ADAMTS3 SYT16 MAP3K21 PRDM16

8.92e-0719023894836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B PDE9A EML6 HUNK CASZ1 HSD11B2 PTBP3 MAP3K21 PRDM16

9.32e-07191238996b78b4e819ea6052334bfcbc7abbf35897df885
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 CASZ1 PPM1L MTCL1 CASR DZIP1 CGNL1 PRDM16 EPB41L1

9.32e-071912389963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

HUNK GLDC HSD11B2 NR1H4 ANK3 ADAMTS3 OGDHL MAP3K21 EPB41L1

9.73e-071922389760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B PDZK1 CASZ1 GLDC ANK3 CASR OGDHL CGNL1 EPB41L1

1.02e-06193238982e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B CASZ1 GLDC PLXNB1 ANK3 CASR CGNL1 MAP3K21 EPB41L1

1.06e-0619423895eaaa81f4b2535f983c424aaef00077089526a5c
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 GLDC TLL1 GKAP1 PRKCZ MAP3K21 PRDM16

1.06e-061942389f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellHealthy/Control-CD4+_Tcm|World / Disease group and Cell class

PDE3B ARHGAP15 RPS4X SYNJ2 SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.06e-061942389cbdd1786305108cbeddea07a21120067d78c59a0
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDE3B KCNE1 ALOX5 TNS3 FNIP2 DMXL2 IVNS1ABP FRMD4A TTLL4

1.11e-0619523899d649ac7d2af313481069c95349efc0c68449e2b
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CWF19L2 PDE3B DGKH CASZ1 SYNE2 VPS13A NKTR ANK3 SUGP2

1.20e-061972389e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYO5B ADGRV1 SYNE2 MTCL1 PLXNB1 ANK3 OGDHL CGNL1 MAP3K21

1.20e-0619723893d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PGBD1 ZNF215 EDC4 STX1A WDR75 FRMD4A TTLL4 ZNF74

1.23e-0614623881bf67a9416f52198931b912a31be4bab09fefd19
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TET2 PDE3B ERCC6 PAK4 TBC1D2B SREBF1 CUEDC1 ALOX5 SLC39A10

1.31e-061992389bbb4798d6a24e756fea744a151ba67c1bafbac9a
ToppCellSepsis-URO-Lymphocyte-T/NK-CD4+_Tem|URO / Disease, condition lineage and cell class

CWF19L2 EPPK1 PDE9A ARHGAP15 RPS4X SYNE2 ANK3 FRMD4A EFNA1

1.37e-0620023898b7bfe6411de9528603481f6e5612cbbb8471cf6
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TET2 BCLAF1 ATAD2B SYNE2 NKTR ANKRD12 DYNC1H1 REL MACF1

1.37e-06200238912f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NET1 ABCA13 DGKH CASZ1 SYNE2 CPLANE1 PLXNB1 ANK3 EPB41L1

1.37e-06200238997f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NET1 ABCA13 DGKH CASZ1 SYNE2 CPLANE1 PLXNB1 ANK3 EPB41L1

1.37e-062002389ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

PDE3B DGKH HUNK SYNE2 NKTR ANKRD12 ANK3 MACF1

2.02e-0615623881545169694f686d28648a68b552c2ae606599d66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B EML6 CASZ1 GLDC HSD11B2 ANK3 ADAMTS3 MAP3K21

2.67e-061622388285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A ADGRV1 PPM1L SLC4A8 CASR DZIP1 CGNL1 PRDM16

4.17e-0617223881565f38266891c3acf49778838de134c5dee5460
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 PDZK1 EML6 HUNK CDKAL1 TNS3 FAT3 RGS12

4.94e-061762388327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 SULF2 ALOX5 PADI1 FRMD4A RUFY4 CDK2

5.37e-061782388de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A SREBF1 ADGRV1 SLC4A8 CASR DZIP1 CGNL1 PRDM16

5.82e-0618023889e09b3dfe344b5d50520711513d389865d73a861
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B EML6 HUNK CASZ1 GLDC HSD11B2 MAP3K21 PRDM16

5.82e-061802388788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

INPP5D PLEKHG1 SULF2 SYNE2 DENND3 IVNS1ABP TLL1 MACF1

5.82e-061802388493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 ABCA13 PDZK1 HUNK TNS3 ADAMTS3 FAT3

6.07e-0618123886956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

ACTN1 DNAJC6 ONECUT1 CRACD DYNC1H1 IVNS1ABP TANC1 CDK2

6.07e-0618123889d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DGKH CASZ1 KIF16B CASR DZIP1 IVNS1ABP CGNL1 EPB41L1

6.07e-06181238822363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDZK1 HUNK GLDC ABCC2 NR1H4 CASR CGNL1 EPB41L1

6.32e-0618223889d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCelldroplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 FRMD4A RUFY4

6.58e-061832388ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DGKH CASZ1 KIF16B CASR DZIP1 IVNS1ABP CGNL1 EPB41L1

6.84e-061842388d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 FRMD4A RUFY4

6.84e-0618423883261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 FRMD4A RUFY4

7.12e-061852388775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 GLDC HSD11B2 PTBP3 ANK3 ADAMTS3 C4orf54 MAP3K21

7.12e-061852388d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ACTN1 STX1A SYNJ2 PPM1L VPS13A ADAMTS3 FAT3 DENND3

7.41e-06186238884ba666237c18189d7e7556bd92dd953af733c00
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B PDZK1 DGKH SULT1C4 SYNE2 MTCL1 NR1H4 ANK3

7.41e-061862388b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B HUNK CASZ1 HSD11B2 PTBP3 SYT16 MAP3K21 PRDM16

7.41e-061862388b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

IGFN1 ADGRV1 PLXNB1 TNS3 GRAMD2B CGNL1 PRDM16 HES5

7.70e-0618723884d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

HUNK CASZ1 CRACD ARID5B SLC4A8 DGKD HDAC7 CGNL1

7.70e-0618723887e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3B EML6 HUNK CASZ1 HSD11B2 ADAMTS3 MAP3K21 PRDM16

7.70e-061872388f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 GLDC HSD11B2 PTBP3 ANK3 ADAMTS3 MAP3K21 PRDM16

7.70e-0618723882d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 HUNK GLDC HSD11B2 ANK3 ADAMTS3 MAP3K21 PRDM16

7.70e-061872388e3095455d2f255854f339f6b05fa87852af0700f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 CASZ1 PPM1L CASR IVNS1ABP CGNL1 PRDM16 EPB41L1

8.01e-0618823882ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NKTR ANKRD12 FNIP2 REL DENND3 FRMD4A MACF1

8.27e-061352387b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 HUNK GLDC HSD11B2 ANK3 ADAMTS3 MAP3K21 PRDM16

8.33e-0618923883a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HUNK CASZ1 GLDC HSD11B2 PTBP3 ADAMTS3 MAP3K21 PRDM16

8.33e-06189238890aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 CRACD SULF2 ALOX5 DMXL2 IVNS1ABP RUFY4 CHP1

8.33e-061892388287e59104687fe1665232c52993889f0f2c97f17
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 ANK3 TLL1 GKAP1 PRKCZ PRDM16

8.33e-0618923887659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 GLDC HSD11B2 PRKCZ MAP3K21 PRDM16

8.65e-061902388625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP15 INPP5D ABCB4 PLEKHG1 EIF2AK3 ALOX5 REL DGKD

8.65e-061902388424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellFetal_29-31_weeks-Immune-B_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP15 INPP5D ABCB4 PLEKHG1 EIF2AK3 ALOX5 REL DGKD

8.99e-06191238884452125d1b5b76974e3f9126f611eff16d45c25
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A ASIC2 DGKH CASR HDAC7 IVNS1ABP SYT16 EPB41L1

8.99e-0619123885a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A ASIC2 DGKH CASR HDAC7 IVNS1ABP SYT16 EPB41L1

8.99e-06191238855ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH11 ACTN1 CASZ1 SULF2 MTCL1 FERMT2 FAT3 NEXN

8.99e-061912388de2cd94ee88a7754f86d39469e38374d668210c7
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FSIP1 TBC1D2B ACTN1 SYNJ2 ARID5B FAT3 FRMD4A ELL

8.99e-06191238808720998aa55131d7377c4c67c4c935865bd7d79
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

PDE3B SYNE2 NKTR ANKRD12 ANK3 NLRP1 IVNS1ABP MACF1

9.34e-06192238847646d7e4990be85072987f92bf18d52f8da752e
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 GLDC HSD11B2 PRKCZ MAP3K21 PRDM16

9.34e-061922388d3634574b2e8d2ded6446969361b70761b331aea
ToppCellHealthy_donor-CD4+_Tcm|World / disease group, cell group and cell class (v2)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

9.34e-0619223881603903454ba6bf65c8e13ede620e0b1e8fbd7ec
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPPK1 MYO5B FSIP1 ADGRV1 GLDC HSD11B2 ARSL PRKCZ

9.34e-06192238839804d9ddc67c1b41887752df2503389eae44a1a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A EML6 HUNK CASZ1 HSD11B2 PTBP3 MAP3K21 PRDM16

9.34e-061922388fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 GLDC HSD11B2 ARSL PRKCZ MAP3K21 PRDM16

9.34e-061922388b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 SALL1 SYNE2 SLC4A8 CASR IVNS1ABP CGNL1 FAM43A

9.34e-061922388ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 GLDC HSD11B2 PRKCZ MAP3K21 PRDM16

9.34e-0619223881aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCelldroplet-Lung-LUNG-1m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 IVNS1ABP CHP1

1.01e-051942388621e0e8fe77ff0be83ea9287ce46e97c47e2b3b9
ToppCellPCW_05-06-Epithelial|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 PLEKHG1 GLDC HSD11B2 TLL1 PRKCZ PRDM16

1.01e-05194238847a1369c22fcbfe00b08376eb610a61c355548db
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B PDZK1 GLDC SYNE2 ANK3 ZNF827 CGNL1 EPB41L1

1.01e-0519423887002937e8903e037332a215d00fbc7c7843b33f2
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NET1 CRACD SULF2 ALOX5 DMXL2 IVNS1ABP ASB4 CDK2

1.01e-051942388effd38e51062b225ecabc7e1c50154e65495d559
ToppCellmild_COVID-19-CD4+_Tcm|mild_COVID-19 / disease group, cell group and cell class (v2)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.01e-051942388cf085813138a73878f9586059cd1d01d1a7ee748
ToppCelldroplet-Lung-1m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NET1 ACTN1 CRACD SULF2 ALOX5 DMXL2 IVNS1ABP CHP1

1.01e-051942388d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PDE3B DGKH SYNE2 ARID5B NKTR ANKRD12 ANK3 MACF1

1.05e-0519523884bdedd924564a260841a9153604026b57487c83d
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_Tcm|COVID-19_Severe / Disease group, lineage and cell class

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.05e-051952388658751e384de50cdcb907d3740fb1a74004a517b
ToppCellmild_COVID-19-CD4+_Tcm|World / disease group, cell group and cell class (v2)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.05e-051952388fc666cd4d00df9cc03127fb73032ae3e46419055
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.05e-051952388e3e5c784e7b494434fb4f6f27e0af22b167842ef
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.05e-051952388d6b8bc4204476220a64afe17e3b6b2ed59853284
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5B ADGRV1 GLDC HSD11B2 ARSL PRKCZ MAP3K21 PRDM16

1.08e-0519623880a34a0009f479384f1994c6f977f942699a132c8
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.08e-051962388a1a1e4e4404a0c590edd07dfc9e7e1b6f720fb0f
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3B ARHGAP15 RPS4X SYNE2 ARID5B ANKRD12 DNAJB1 ANK3

1.08e-051962388459408882babf1fb56b37dc52ec119ac0b0153a7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE9A MYO5B SYNE2 NR1H4 TNS3 PTBP3 ANK3 EPB41L1

1.13e-0519723887e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ComputationalGenes in the cancer module 277.

GAPVD1 USP25 MIB1 CENPT LTN1 PAK2

6.67e-05551376MODULE_277
Drugpurealin

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B DYNC1H1

1.27e-07582328CID006419303
Drugfast white

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

2.08e-07422327CID000024008
Drugoxovanadium

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B PDZK1 ALOX5 DYNC1H1

4.34e-0712023210CID000024411
Drugformycin triphosphate

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B

8.24e-07512327CID000122274
Drug2,4,4'-trichlorobiphenyl

MYH13 ASIC2 ABCA13 TOPAZ1 PENK SPCS2 HUNK DNAJC6 CASZ1 GMPS SENP1 ATAD2B SYNE2 PRRG3 ANKRD12 CKAP4 HSD11B2 ABCC2 TNS3 PTBP3 ADGRG3 FAT3 CAPZA1 SLC39A10 FRMD4A ZNF182 PBRM1 TLL1 PRIM2 CCDC74A LTN1 OGDHL TANC1 RUFY4 CDK2

9.53e-07141123235ctd:C081766
Drug2,4,5,2',5'-pentachlorobiphenyl

MYH13 ASIC2 ABCA13 TOPAZ1 PENK SPCS2 HUNK DNAJC6 CASZ1 GMPS SENP1 ATAD2B SYNE2 PRRG3 ANKRD12 CKAP4 HSD11B2 ABCC2 TNS3 PTBP3 ADGRG3 FAT3 CAPZA1 SLC39A10 FRMD4A ZNF182 PBRM1 TLL1 PRIM2 CCDC74A LTN1 OGDHL TANC1 RUFY4 CDK2

1.54e-06144123235ctd:C009828
Drugblebbistatin

MYH1 MYH2 MYH3 MYH4 MYH11 MYH13 MYO5B ACTN1 ABCB4

3.00e-061162329CID003476986
Drug4-chloroaniline

MYH1 MYH2 MYH3 MYH4 PDE3B MYH11 MYH13 MYO5B CKAP4 TNFSF11 HTR3B

7.65e-0620223211CID000007812
DrugGlucose

MYH2 GAPVD1 RPS4X SREBF1 DGKH FOXN3 HUNK CASZ1 AMOT RAB3GAP2 MIB1 VPS13A HSD11B2 ABCC2 FERMT2 ALOX5 DMXL2 DGKD APOB HS1BP3 SLC39A10 RGS12 IVNS1ABP PIKFYVE ZNF750 EFNA1 PBRM1 PRIM2 GKAP1 PRKCZ MAPK8 ELL DOP1A

8.05e-06142023233ctd:D005947
DrugVincristine

MYH11 ARHGAP15 BCLAF1 EML6 SREBF1 USP25 FAM13B ABCB4 PLEKHG1 SENP1 GCLC SYNE2 VPS13A MKLN1 ABCC2 FERMT2 ANAPC5 TENT2 NR1H4 DNAJB1 REL TMEM43 FAM171B GPATCH2L IVNS1ABP SBNO1 GRAMD2B MACF1 CDK2

1.11e-05118223229ctd:D014750
Druggepirone

MYH1 PENK PKDREJ TRIM32 HTR3B

1.22e-05302325CID000055190
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

6.30e-09102275DOID:0080326 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

1.95e-08122275DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

1.95e-08122275DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

3.16e-08132275DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

7.27e-08152275DOID:0050646 (implicated_via_orthology)
DiseaseSchizophrenia

MYO5B ABCA13 PDZK1 SREBF1 PGBD1 ARHGEF11 TRRAP STX1A GCLC VRK2 ANK3 ADAMTS3 ADNP2 RGS12 PBRM1 SBNO1 PAK2 ZNF74 CGNL1 HTR3B MAPK8

5.34e-0688322721C0036341
Diseasecardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13 CASR

1.83e-05712276DOID:0050700 (implicated_via_orthology)
DiseaseArthrogryposis

MYH3 ERCC6 DYNC1H1 VIPAS39

1.84e-05212274C0003886
DiseaseCholestasis of pregnancy

ABCB4 ABCC2 NR1H4

2.45e-0582273C0268318
DiseaseParkinson's disease (implicated_via_orthology)

MINAR2 PAK4 SPCS2 DNAJC6 SYNJ2 VPS13A PAK5 MAPK8

3.10e-051572278DOID:14330 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

3.37e-05482275DOID:423 (implicated_via_orthology)
DiseaseX-linked spondyloepiphyseal dysplasia tarda (implicated_via_orthology)

TRAPPC2 TRAPPC2B

5.89e-0522272DOID:0080362 (implicated_via_orthology)
Diseasesphingomyelin measurement

ETFDH CHRNE SENP1 SYNE2 DYNC1H1 SLC4A8 KIF16B NLRP1 CASR APOB

6.40e-0527822710EFO_0010118
Diseaselevel of Sphingomyelin (d38:1) in blood serum

CHRNE SYNE2 ADAMTS3 NLRP1

7.99e-05302274OBA_2045180
Diseasenon-high density lipoprotein cholesterol measurement

PDE3B FOXN3 ONECUT1 CDKAL1 ABCB4 ZC3H4 SYNE2 OSBPL9 NR1H4 SLC4A8 ADAMTS3 ADNP2 APOB PBRM1 ARSL SBNO1

1.42e-0471322716EFO_0005689
Diseasereticulocyte measurement

PDE3B INPP5D EML6 CDKAL1 ABCB4 SENP1 ZC3H4 ATAD2B SYNE2 VPS13A ALOX5 TNS3 DENND3 PIKFYVE PACS1 ZNF827 LTN1 PAK2 PRDM16 ELL

2.02e-04105322720EFO_0010700
Diseasecolorectal cancer (is_marker_for)

TET2 ERCC6 ADGRB1 GCLC HDAC7 PBRM1 BARHL2

2.23e-041572277DOID:9256 (is_marker_for)
DiseaseMalignant neoplasm of breast

MYH1 ERCC6 NET1 RPS4X PDZK1 PKDREJ SULF2 SYNJ2 SYNE2 POP1 ANAPC5 PLXNB1 KIF16B HDAC7 EFNA1 PBRM1 SBNO1 TLL1 MACF1 DOP1A

2.61e-04107422720C0006142
Diseasecarcinoid tumor

CDKAL1 KIF16B

3.50e-0442272EFO_0004243
Diseaseintrahepatic cholestasis (implicated_via_orthology)

ABCB4 NR1H4

3.50e-0442272DOID:1852 (implicated_via_orthology)
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE2 TMEM43

3.50e-0442272cv:CN293514
DiseaseCholestasis, progressive familial intrahepatic 1

MYO5B ABCB4

3.50e-0442272C4551898
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH3 MYH4 MYH13

3.88e-04802275DOID:12930 (implicated_via_orthology)
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE2 TMEM43

5.80e-0452272C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE2 TMEM43

5.80e-0452272C0410190
Diseasechronic mucocutaneous candidiasis (is_implicated_in)

IL17F MAPK8

5.80e-0452272DOID:2058 (is_implicated_in)
Diseaseatopy

ADGRV1 PAK5

5.80e-0452272EFO_0002686
Diseasehemoglobin A1 measurement

TET2 PDE3B ETFDH FOXN3 CDKAL1 PLEKHG1 ZC3H4 SYNE2 VPS13A DGKD PAK2 MACF1

7.56e-0452022712EFO_0007629
DiseaseEmery-Dreifuss muscular dystrophy

SYNE2 TMEM43

8.66e-0462272cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE2 TMEM43

8.66e-0462272C0410189
Diseasespondyloepiphyseal dysplasia congenita (implicated_via_orthology)

TRAPPC2 TRAPPC2B

8.66e-0462272DOID:14789 (implicated_via_orthology)
Diseasehematocrit

PDE9A ARHGAP15 SREBF1 ADGRV1 CDKAL1 PLEKHG1 SENP1 SALL1 ZC3H4 DGKD APOB SLC39A10 GPATCH2L FRMD4A GRAMD2B CGNL1 PRDM16 ELL

8.87e-04101122718EFO_0004348
Diseasecoronary artery disease

ANKRD31 TET2 CWF19L2 MYH11 ARHGAP15 ASIC2 INPP5D SREBF1 KIAA0319 PLEKHG1 CRACD SENP1 PAN2 TNS3 ADAMTS3 APOB ZNF827 PRIM2 PRDM16 ELL

9.78e-04119422720EFO_0001645
Diseaseprimary aldosteronism

EML6 CASZ1 DMXL2

1.03e-03262273MONDO_0001422
DiseaseR-warfarin measurement

PDE3B ZNF142 PDE9A MYO5B CDKAL1 RAB3GAP2 KATNIP FARS2

1.09e-032652278EFO_0803324
Diseasetriglycerides to total lipids in large HDL percentage

ETFDH STX1A APOB RGS12

1.19e-03602274EFO_0022330
Diseaseplatelet crit

ANKRD31 TET2 MYH13 ACTN1 ADGRV1 ARHGEF11 FAM13B CHRNE SENP1 ARID5B KIF16B DGKD APOB HDAC7 SBNO1 PAK2 PRDM16

1.19e-0395222717EFO_0007985
DiseaseSeckel syndrome (implicated_via_orthology)

ATRIP CENPT

1.21e-0372272DOID:0050569 (implicated_via_orthology)
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE2 TMEM43

1.21e-0372272C0751337
DiseaseAgents acting on the renin-angiotensin system use measurement

CWF19L2 MYH11 ARHGAP15 CASZ1 PLEKHG1 ANAPC5 HDAC7 RGS12 PRDM16

1.22e-033352279EFO_0009931
Diseasecomplex trait

ANKRD31 GAPVD1 CHD6 DMXL2 TRIM54 APOB SUGP2 MACF1

1.25e-032712278EFO_0010578
Diseasediastolic blood pressure, unipolar depression

NAT1 PLEKHG1 CAPZA1

1.56e-03302273EFO_0003761, EFO_0006336
Diseasehelix rolling

SULT1C4 CCNYL2

1.60e-0382272EFO_0007670
Diseaseperiodontitis

EPPK1 MYH13 ACTN1 HUNK GVINP1 FAT3 FAM180A

1.77e-032232277EFO_0000649
Diseaselevel of Sphingomyelin (d40:1) in blood serum

CHRNE ADAMTS3 NLRP1

1.89e-03322273OBA_2045182
Diseasecup-to-disc ratio measurement

MINAR2 SALL1 ARID5B MTCL1 DNAJB1 ANK3 FRMD4A SNCAIP TCP11L2 PRDM16

1.94e-0343022710EFO_0006939
Diseaseoctanoylcarnitine measurement

ETFDH FNIP2

2.05e-0392272EFO_0021042
Diseasethoracic aortic calcification measurement

CDKAL1 VPS13A

2.05e-0392272EFO_0010273
Diseasecholestasis (implicated_via_orthology)

ABCB4 ABCC2

2.05e-0392272DOID:13580 (implicated_via_orthology)
Diseasepanic disorder

USP25 PLEKHG1 PTBP3

2.07e-03332273EFO_0004262
Diseasenephrolithiasis

DGKH CASR DGKD

2.07e-03332273EFO_0004253
DiseaseNon-alcoholic Fatty Liver Disease

SREBF1 ABCB4 ABCC2 NR1H4

2.10e-03702274C0400966
DiseaseNonalcoholic Steatohepatitis

SREBF1 ABCB4 ABCC2 NR1H4

2.10e-03702274C3241937
Diseasetestosterone measurement

TET2 MYH2 FOXN3 ONECUT1 PKDREJ ZC3H4 SYNE2 ARID5B NR1H4 TNS3 VRK2 ANK3 ADAMTS3 CAPZA1 EFNA1 TLL1 GKAP1 C18orf63 MACF1 CHP1

2.12e-03127522720EFO_0004908
Diseaseatrial fibrillation

MYH11 FAM13B CASZ1 SULF2 SYNE2 CRAMP1 HS1BP3 PAK2 CGNL1

2.44e-033712279EFO_0000275
Diseasecerebrospinal fluid clusterin measurement

ABCA13 FOXN3 TLL1

2.45e-03352273EFO_0007657
Diseaseserine measurement

DYNC1H1 PACS1 GRAMD2B

2.45e-03352273EFO_0009774
Diseasemean platelet volume

TET2 MYH11 ARHGAP15 EML6 ACTN1 SULT1C4 CHRNE CUEDC1 ATAD2B SYNE2 HSD11B2 CAPZA1 KIF16B CASR HDAC7 RGS12 PRDM16

2.45e-03102022717EFO_0004584
Diseasesleep duration, high density lipoprotein cholesterol measurement

MYO5B APOB SBNO1 MACF1 CGNL1

2.49e-031212275EFO_0004612, EFO_0005271
Diseasepancreatic adenocarcinoma (is_marker_for)

ADGRB1 MAPK8

2.55e-03102272DOID:4074 (is_marker_for)
Diseasepulse pressure measurement

TET2 CWF19L2 MYH11 ETFDH PGBD1 CASZ1 CDKAL1 PLEKHG1 SENP1 ATAD2B MKLN1 FERMT2 TNS3 TRAF7 FAT3 SLC39A10 PBRM1 ZNF827 PRDM16 ELL CCNYL2

2.62e-03139222721EFO_0005763
Diseaseexecutive function measurement

TET2 HUNK PLEKHG1 KATNIP ABCC2 DMXL2 VRK2 PAK5 BARHL2

2.67e-033762279EFO_0009332
Diseaseobesity

NAT1 EML6 CRACD DGKD PACS1 FARS2 PRDM16

2.74e-032412277EFO_0001073
Diseasemelanoma

TET2 ADGRV1 CDKAL1 MKLN1 EPB41L1

2.96e-031262275EFO_0000756
Diseasecytochrome p450 3a4 measurement

APOB PIKFYVE

3.10e-03112272EFO_0020303
DiseaseSodium measurement

KCNE1 TRAPPC2

3.10e-03112272C0337443
DiseaseAdverse Event by CTCAE Category

KCNE1 TRAPPC2

3.10e-03112272C1879645
Diseaselevel of Sphingomyelin (d34:0) in blood serum

CHRNE SYNE2

3.10e-03112272OBA_2045176
DiseaseJT interval

FOXN3 FAM13B CASZ1 KCNE1 FERMT2 CASR DGKD

3.21e-032482277EFO_0007885
Diseasecalcium measurement

ANKRD31 TET2 ASIC2 TBC1D2B SREBF1 CHRNE SYNE2 CASR DGKD RGS12 MACF1 CGNL1

3.62e-0362822712EFO_0004838
Diseasebrain measurement, neuroimaging measurement

MIB1 VRK2 ANK3 ADAMTS3 FAT3 DENND3 PBRM1 SBNO1 MACF1 PRKCZ PRDM16

3.76e-0355022711EFO_0004346, EFO_0004464
Diseasecortical surface area measurement

TET2 FSIP1 SREBF1 ADGRV1 CDKAL1 PLEKHG1 SULF2 RAB3GAP2 ATAD2B MTCL1 FNIP2 VRK2 ANK3 ADAMTS3 FAT3 DENND3 TLL1 MACF1 PRKCZ PTPN20

3.88e-03134522720EFO_0010736
Diseasesnoring measurement

ADGRV1 SULF2 CRAMP1 MACF1

4.07e-03842274EFO_0008341
DiseaseAmino Acid Metabolism, Inherited Disorders

GCLC XPC

4.35e-03132272C0750905
DiseaseAmino Acid Metabolism, Inborn Errors

GCLC XPC

4.35e-03132272C0002514
DiseaseHypercalcemia

CASR TNFSF11

4.35e-03132272C0020437
DiseaseMilk-Alkali Syndrome

CASR TNFSF11

4.35e-03132272C0026141
Diseaselung non-small cell carcinoma (is_implicated_in)

TET2 NAT1 ERCC6 ABCC2 PBRM1

4.50e-031392275DOID:3908 (is_implicated_in)
DiseaseAlzheimer disease

ANKRD31 INPP5D CHRNE PLEKHG1 FERMT2 SLC4A8 ANK3 DENND3 FRMD4A EFNA1

4.56e-0348522710MONDO_0004975
Diseasecholesteryl ester 20:5 measurement

CDKAL1 CKAP4 TCP11L2

4.72e-03442273EFO_0010349
Diseaseinsulin measurement

TET2 ETFDH DGKH CASZ1 CDKAL1 CHD6 HDAC7

4.79e-032672277EFO_0004467
Diseaseserum gamma-glutamyl transferase measurement

FSIP1 ARHGEF11 SALL1 SYNJ2 GCLC ABCC2 ANAPC5 NR1H4 SLC4A8 NLRP1 EFNA1 PBRM1 SBNO1 ZNF827 CGNL1

5.00e-0391422715EFO_0004532
DiseaseLeft ventricular noncompaction

MIB1 PRDM16

5.05e-03142272C1960469
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

ADAMTS3 APOB

5.05e-03142272EFO_0004611, EFO_0008589
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

ANKRD31 ETFDH SYNE2 APOB MACF1

5.23e-031442275EFO_0004611, EFO_0020943
Diseasesleep duration, low density lipoprotein cholesterol measurement

ANKRD31 GCLC APOB ZNF827

5.41e-03912274EFO_0004611, EFO_0005271
Diseasenevus count, cutaneous melanoma

ADGRV1 CDKAL1 SYNE2 MKLN1

5.41e-03912274EFO_0000389, EFO_0004632
DiseaseDown syndrome (implicated_via_orthology)

SYNJ2 DOP1A

5.79e-03152272DOID:14250 (implicated_via_orthology)
Diseaseinfant head circumference

CDKAL1 SBNO1

5.79e-03152272EFO_0004577
Diseasecortical thickness

ASIC2 SREBF1 ADGRV1 PLEKHG1 SULF2 MTCL1 FNIP2 VRK2 ADAMTS3 FAT3 CAPZA1 DENND3 TNFSF11 MACF1 PRKCZ PTPN20 ELL

5.85e-03111322717EFO_0004840
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

TET2 SYNE2 ALOX5 PBRM1 MAPK8

5.86e-031482275C0279702
Diseaseplatelet component distribution width

GAPVD1 MYH13 ARHGAP15 ACTN1 CHRNE SYNJ2 ATAD2B KIF16B HDAC7 C4orf54 PAK2 MACF1 PRDM16

5.95e-0375522713EFO_0007984
Diseaseresting heart rate

MYH11 EPPK1 SREBF1 MKLN1 TANC1

6.02e-031492275EFO_0004351

Protein segments in the cluster

PeptideGeneStartEntry
KSASPHKDLPNDRLV

TDRD1

896

Q9BXT4
FNISLQRKLVPKHGD

NAT1

271

P18440
KTDGPVFHSNTLERK

AMOT

1051

Q4VCS5
IDPLANKKPRISHFT

ELL

331

P55199
HEQFKATLPDADKER

ACTN1

551

P12814
PDKGRKALESHADTI

AGAP11

101

Q8TF27
LPKATHQKEFDTLSG

ANKRD30B

591

Q9BXX2
LQEVASFLKRNKHGP

ARSL

276

P51690
ELRQLKSDSHGPKED

CKAP4

376

Q07065
ASSKEEPKTNRLHIG

EIF2AK3

816

Q9NZJ5
DFPNHSLTLKRDKAP

ADGRB1

1301

O14514
ARKISFEKLHAGSTP

CASZ1

201

Q86V15
EIHFLNKPASKDSRG

ADAM7

731

Q9H2U9
NARDDDFKSPLHKAA

ASB4

246

Q9Y574
AFLRSPEDIQHDKKA

HTR3B

186

O95264
HFGVAAKDQDLKSRP

CASR

41

P41180
FKFDHLRKEASDPQP

CAPZA1

96

P52907
LRAPEHSNKSKDRDN

GVINP1

1546

Q7Z2Y8
PKRKDTRGFSHFAEV

ADGRV1

5701

Q8WXG9
FQDLEKLKSRPAHLG

ARHGEF11

311

O15085
NHLKSLKRDPSATDA

ABCA13

776

Q86UQ4
SRERFKSEDAPKIHV

ADGRG3

296

Q86Y34
PPFSKDHAQLSSKLR

DOP1A

396

Q5JWR5
EKNLPLDGKRQRFHS

TENT2

81

Q6PIY7
QGKDRPLTVSLKDFH

GKAP1

171

Q5VSY0
ALSAKKDQPDFISHR

DMXL2

1916

Q8TDJ6
RKENEPEAEKTHLFA

ANKRD12

386

Q6UB98
TKLDPEGKSAFHLAA

ANKRD24

76

Q8TF21
KPGDISRVLEFTKAH

HSD11B2

141

P80365
ETLKHKINPSAGEAF

DENND3

876

A2RUS2
PRDQEATHFPKVSTK

CCDC74A

316

Q96AQ1
PRDQEATHFPKVSTK

CCDC74B

316

Q96LY2
DKPHNIFKRDGSDVI

DNAJB1

241

P25685
PARLISGEEHFSSKK

DCUN1D5

36

Q9BTE7
ADHDVPKRKKFPASN

ERCC6

1046

Q03468
LKKPRSELVFEGQRH

CHRNE

386

Q04844
DSSFSVKRKLPDGHL

ADNP2

971

Q6IQ32
PSVLEALRQKANFKH

ASIC2

131

Q16515
SSKTFNLRVREHPKE

KIF16B

166

Q96L93
LPEREIANSKDFHRK

RAD51AP2

906

Q09MP3
SHKLVLNVPFSDSKR

PADI1

196

Q9ULC6
LAESPRNGLQEKHKS

EDC4

841

Q6P2E9
QLTHELSKFKFEPPR

MTCL1

661

Q9Y4B5
DVRPARKSEAPFTHK

NEXN

496

Q0ZGT2
NKKLPSGHSDLLEER

NR1H4

351

Q96RI1
KKHRITAEIFSPNDK

OSBPL9

601

Q96SU4
QFKRETASLKLLPHQ

PDZK1

226

Q5T2W1
KRKESFFPLTEGNLH

LTN1

1111

O94822
ENSKPEESHLLAKRY

PENK

86

P01210
KAKNIFRIRFHDPSP

NET1

461

Q7Z628
ASEVLKHLKERFPPN

ANAPC5

486

Q9UJX4
RLPLTDAQLHEQFKK

ANKAR

471

Q7Z5J8
LKLKDSNFERHQPDT

C8orf48

91

Q96LL4
FPKSRHSDGTEKNKL

ANKRD31

1531

Q8N7Z5
KKKIEISGPSNFEHR

PAK5

6

Q9P286
NVPFHLALSDKKSER

RAB3GAP2

536

Q9H2M9
LELSKNGTEPESFHK

PAN2

1151

Q504Q3
QETTPRHKQEFLDKP

EPB41L1

486

Q9H4G0
PNETFHLATRKFLEK

PBRM1

1001

Q86U86
HRDLKPENLLFKDNS

MAPKAPK5

146

Q8IW41
GFEINLDHRKLKTPQ

ATPAF2

61

Q8N5M1
SDDDHIQFVQKKPPR

IVNS1ABP

246

Q9Y6Y0
VDEDRPKIFPKSHSL

GPR179

1061

Q6PRD1
RISPCLAQDLKHFKE

NLRP10

536

Q86W26
PSSHFVRRKKSEPDD

GOLGA5

106

Q8TBA6
VLEFNPASKSHKRER

KATNIP

261

O60303
KFEPGTQRFELHKKA

MOB3A

21

Q96BX8
KKRENTLFDIHRSPA

ATAD2B

306

Q9ULI0
FQESSPLPHKHERKD

LINC02693

141

A8MQB3
QRFLHDPEKLDSSSK

FAM13B

531

Q9NYF5
DENKLHGKPDKTLRF

GAPVD1

551

Q14C86
NPSDHPKASTIFLRK

CCNYL2

81

Q5T2Q4
TLADHKLGRDSPINK

PLXNB1

2021

O43157
TLKGKLARQHPEAFS

KXD1

86

Q9BQD3
KSLLRHPEAKSSFDQ

OGDHL

846

Q9ULD0
PDVLFPADSEHNKLK

MAPK8

276

P45983
HPDKFLQLDVKSLTR

MINAR2

11

P59773
KKRQEAPPHIFSISD

MYH2

146

Q9UKX2
NQHLSGLARKFPDVK

PDCL3

131

Q9H2J4
ADINGPAKVRDLHLK

PDE3B

936

Q13370
SFLDNHKKLTPRRDV

PDE9A

226

O76083
QKKTLFSPDDLRKHG

NLRP1

581

Q9C000
PSDDEELSFHSKGRK

CWF19L2

371

Q2TBE0
PAVSEDALFRDKLKH

CUEDC1

296

Q9NWM3
KSLFFPDEAINKHPR

GCLC

171

P48506
HAIFKENKRPSKELQ

ONECUT1

401

Q9UBC0
AKNLKTFLRHTGPEE

ABCC2

856

Q92887
LKSRPELEHQASGTK

LRRC29

46

Q8WV35
KKRQEAPPHIFSISD

MYH1

146

P12882
AKISLEFNNKREEHP

DGKH

781

Q86XP1
KKAIQDPAFSDGIRH

HUWE1

516

Q7Z6Z7
SEAAARKIPKVGHTF

IL17F

26

Q96PD4
RKNIEPTHAPFIEKS

MACF1

6946

Q9UPN3
QPIDHEGIKSKLSDR

PACS1

256

Q6VY07
SEGDTPLHDAISKKR

MIB1

561

Q86YT6
KIDSFSERGHKPDSI

ABCB4

376

P21439
SEKVKLSLRNFPHND

PTPN20

51

Q4JDL3
QESKHSDPFRSKILK

POP1

896

Q99575
FRHSDPELLKQKLQS

PRIM2

386

P49643
EKRGSAKELLQHPFL

PAK2

486

Q13177
RIQPKNSDPFAHSKD

PIKFYVE

1161

Q9Y2I7
QLDRRVLEHDFPKKS

FRMD4A

76

Q9P2Q2
APKATFERGLELHAK

ETFDH

226

Q16134
HKLNIPKLDFSSQAD

APOB

2891

P04114
AFGKDFHLRLKPNTQ

ADAMTS3

86

O15072
NAHQPKLLERKDTAG

CEFIP

281

Q711Q0
DFSASVKKPHTLLQR

GMPS

471

P49915
VTRLAAFKSAKHRPE

HS1BP3

46

Q53T59
FPKLDLVLSKSSRHN

CPLANE1

616

Q9H799
SAKHGPEKLSEKFQR

EFNA1

96

P20827
EKILEDFRKTHSPDA

CHD6

756

Q8TD26
DRKDGSVKPSHLLNF

CGNL1

131

Q0VF96
VKNPAEDHFRNSIKK

CDKAL1

111

Q5VV42
DHPPIKAFSEKRTSQ

FNIP2

456

Q9P278
RQHFAKARKVPSDTL

FOXN3

421

O00409
RSIFDHIKLPQASKS

BCLAF1

586

Q9NYF8
PLAIARLDNSAAKHK

CRACD

146

Q6ZU35
FAAHAGRKTVKPEDL

CENPT

501

Q96BT3
SRHGKLFSPSKEAEL

CRAMP1

841

Q96RY5
PAIAAVQKFHREKSA

DDX11L8

891

A8MPP1
KLDKRLDRETSPAFH

FAT3

2766

Q8TDW7
PRRALHKQKDGTEFK

MRPL58

26

Q14197
EQEKRGDFLHRPFSK

HUNK

441

P57058
FNAHKDKKGPRTIAE

DNAJC6

791

O75061
SRGDINLKDFLPEKH

ANK3

2366

Q12955
KPRKARTAFSDHQLN

BARHL2

231

Q9NY43
HDPFPDKAAREQLAK

DUXB

36

A0A1W2PPF3
KHKFELLAEAPPRQA

FAM43A

6

Q8N2R8
ISLDFNNKRDEHPEK

DGKD

776

Q16760
KPFSNTEKIELRGKH

FSIP1

236

Q8NA03
DTVALKHFPNIDREK

DYNC1H1

2851

Q14204
LSSHPGILKKEDFER

FAM180A

111

Q6UWF9
EKNKALASDFPHISA

GPATCH2L

351

Q9NWQ4
IRSKKLEHSNDPFNV

KCNE1

66

P15382
FKLDSTPLKAAQHDL

KATNA1

76

O75449
HFRVVAKNELGASKP

IGFN1

1111

Q86VF2
QSKEKNHAVPFLKRE

EML6

656

Q6ZMW3
NHAVPFLKREKAPED

EML6

661

Q6ZMW3
EDSKPHSLRGDSIKQ

ATRIP

276

Q8WXE1
EHFPLRKTVSEPNLK

HDAC7

146

Q8WUI4
PNKRISAKAALAHPF

CDK2

271

P24941
ADAKLQFTPQHKLLR

FERMT2

86

Q96AC1
DAHVNRVPEGKAKSL

GRAMD2B

306

Q96HH9
AQDHAKKFIAVPARL

C4orf54

576

D6RIA3
DFPDHKPRKSTDENV

SAMD15

311

Q9P1V8
QEFHKSPSIEEKPQR

SALL1

936

Q9NSC2
IGRKLSDHKLNNTPD

SLC39A10

541

Q9ULF5
LQSLIEKHFPAPDRK

SBNO1

661

A3KN83
GSLKLKRQPHIFESD

C18orf63

586

Q68DL7
PVAQVRHSFIDLKKG

FAM171B

681

Q6P995
LSYIRSKKLEHSNDP

KCNE1B

66

A0A087WTH5
SILKKRNDTVGDHPA

CNST

621

Q6PJW8
KKRVEISAPSNFEHR

PAK4

6

O96013
FKLVEVKGPNDRLSH

FAN1

971

Q9Y2M0
EHDPFKRSADSELKA

RUNDC1

526

Q96C34
AKVFAPERDEHVKSA

SKOR1

771

P84550
VADSSRKEILHFPKG

TRIM32

591

Q13049
DNFKSLSLSKLEDPH

TMEM43

201

Q9BTV4
LKAESKPRDLYSHAQ

TLL1

891

O43897
LEQKPKFSRSLLTHG

SYT16

221

Q17RD7
QEALPEKSLAGRVKH

TCP11L2

91

Q8N4U5
ANSLPHFKDGREKTV

SYNE2

1491

Q8WXH0
RKKSAPAAFHLQVLQ

SYNJ2

1336

O15056
HKDLPRDIQFDSEKG

ALOX5

161

P09917
KLKDGHRISLPSDFQ

MAP3K21

506

Q5TCX8
LKENLSDHLRNGSKP

NKTR

861

P30414
KHRFEEKAQVDPLSA

MKLN1

641

Q9UL63
TAFSDKRVHVLQGPK

PKDREJ

441

Q9NTG1
AHNLLVKAEPKSPRD

PRDM16

746

Q9HAZ2
PKANKGHSVEEALRA

EPPK1

656

P58107
FHAIKNAIDRLPKDS

ARHGAP15

181

Q53QZ3
FIKERLDEPHFGAKS

PPM1L

316

Q5SGD2
QQRHLPFFLEKKGES

RUFY4

241

Q6ZNE9
RSKEKGLPSVHAFNT

SENP1

481

Q9P0U3
GDKKLSPFNITHRFT

INPP5D

566

Q92835
KDFLNKTFSDPHGRK

SNCAIP

256

Q9Y6H5
HLTAAKPKRSFIESN

TANC1

1846

Q9C0D5
KKRQEAPPHIFSISD

MYH4

146

Q9Y623
KKRQEAPPHIFSISD

MYH3

146

P11055
KGRFAVHRITPEEAK

RPS4X

106

P62701
RSFAEVGKKQSDPHL

SLC4A8

236

Q2Y0W8
SAHLQEKNPRDKAVV

PGBD1

191

Q96JS3
LKDKEPGSFIVRDSH

TNS3

1186

Q68CZ2
SASFLPQSKHKELRA

REELD1

391

A0A1B0GV85
GTLKDAHEFKEDRSP

DZIP1

341

Q86YF9
EFARHQPNSKLEKAD

HES5

46

Q5TA89
DSKAKPEQRPSLHSR

SREBF1

466

P36956
REQNKHIKLPSSFEK

CCDC15

711

Q0P6D6
SLHLQDKKSAAAEAP

ARID5B

886

Q14865
TLAHFRPIEDNEKSK

CHP1

86

Q99653
EEPSSKREHQPFKVL

C12orf29

21

Q8N999
PNHEKRSGKLDAFLV

MYH11

681

P35749
DIYKQESSRPLHSKA

TRIM54

106

Q9BYV2
NRKHVEFESPIPEAK

ZNF750

371

Q32MQ0
VDEPGKHRESKDNFL

ZNF684

86

Q5T5D7
LSLHQRIKNGEKPFE

ZNF182

221

P17025
QKIHSEGFLSKRSDP

ZNF749

271

O43361
FSLKNCILDDKRPHV

VPS13A

1451

Q96RL7
SIFGPHRNVRKTKED

RGS12

611

O14924
KNKEFLPRLGATIEH

WDR75

281

Q8IWA0
EKSIFLVAHRKDPTG

SPCS2

136

Q15005
RKHSAILASPNPDEK

STX1A

56

Q16623
DFPLSSEVRKKLEQH

SPATA31D1

676

Q6ZQQ2
VPDSEQDIKPRFHKS

TNPO2

326

O14787
KSKRAPTHQRFPFLE

SULT1C4

76

O75897
KFLKHSALKTPRVDN

SUGP2

386

Q8IX01
LEQPSRSDFSKHLKE

USP25

741

Q9UHP3
PFTIKLSARKDHEGS

TRAF7

211

Q6Q0C0
KKRQEAPPHIFSISD

MYH13

146

Q9UKX3
KKEPNLFSHDAVVRE

REL

361

Q04864
KEFAHVNRADSPPKE

ELAC1

136

Q9H777
ESAGQTEIFRKHPRK

VIPAS39

311

Q9H9C1
ENYDIPSADRHKSKL

UBA1

871

P22314
GLTKDFSNSPLHRFK

PTBP3

446

O95758
EFLPAGKAESKDDHR

TRAPPC2

21

P0DI81
NFSHDIELPKKRELC

ZC3H4

411

Q9UPT8
KRSKLEAQPFAHLTI

TNFSF11

156

O14788
ADRPANHTKLKDPSE

ZNF827

541

Q17R98
RFLGKHSVLKLQNPE

TOPAZ1

1056

Q8N9V7
KASKQERENPLAHLA

USP41

36

Q3LFD5
NSLRKAHLLSKPFES

ZNF215

201

Q9UL58
RLHSEGKPLAIQFNK

ZNF74

576

Q16587
LHPAQRSLSKDGTKE

ZNF597

31

Q96LX8
TPELAFTKRQAGHSK

PLEKHG1

696

Q9ULL1
SPTEALKKHRFEQGK

ZNF142

1011

P52746
GDDLRDFPSDLKKAH

XPC

96

Q01831
RKFENLTDPCRNHKS

RAPGEFL1

546

Q9UHV5
FDSLLIPADHPSRKK

FARS2

126

O95363
EFLPAGKAESKDDHR

TRAPPC2B

21

P0DI82
KSPSFRSIREHQKLN

TTLL4

646

Q14679
ELKAPRFHQAESHLK

TET2

566

Q6N021
SFLKPRPHNIKDSFS

TIGD7

526

Q6NT04
DVPQHPDFKDRLEKS

ZNF619

116

Q8N2I2
PDFKDRLEKSQLHDT

ZNF619

121

Q8N2I2
VDRHTRKFKDNTEPG

TBC1D2B

676

Q9UPU7
LAKSKSVHQDYLPDR

THEGL

386

P0DJG4
EAKDAHSVLKRFPRA

PRRG3

6

Q9BZD7
KKEHERSNASPAIFP

TRRAP

2801

Q9Y4A5
SLHPFRKGLQEKDKV

SULF2

681

Q8IWU5
AFPTNKPEKDARHVV

VRK2

46

Q86Y07
IFAGVHDEKAKPRDR

TLE6

166

Q9H808
HEFILDTRPFKKSAN

GLDC

861

P23378
PFKVLKAAEVARNLH

KIAA0319

876

Q5VV43
SHVLKGFLNKDPKER

PRKCZ

486

Q05513
FPTNHERISEKKLPS

LRIG2

971

O94898
NDEKLPFHFDPKRAV

MYO5B

661

Q9ULV0