Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessgonadal mesoderm development

TSPY3 TSPY2 TSPY1 TSPY8 TSPY10

1.15e-0892065GO:0007506
DomainYIPPEE

YPEL1 YPEL3 YPEL2

1.19e-0552003PS51792
DomainCUB

CSMD2 LRP12 CUBN TLL2 CUZD1 CSMD1

1.33e-05492006PF00431
DomainCUB

CSMD2 LRP12 CUBN TLL2 CUZD1 CSMD1

1.50e-05502006SM00042
Domain-

CSMD2 LRP12 CUBN TLL2 CUZD1 CSMD1

1.89e-055220062.60.120.290
DomainCUB

CSMD2 LRP12 CUBN TLL2 CUZD1 CSMD1

2.11e-05532006PS01180
DomainCUB_dom

CSMD2 LRP12 CUBN TLL2 CUZD1 CSMD1

3.22e-05572006IPR000859
DomainZnf_C2H2-like

ZNF765 ZNF266 WIZ ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF804B ZNF761 ZNF350 ZNF396 DHX34 ZNF554

4.61e-0579620022IPR015880
DomainZnF_C2H2

ZNF765 ZNF266 WIZ ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF804B ZNF761 ZNF350 ZNF396 DHX34 ZNF554

5.75e-0580820022SM00355
DomainYippee/Mis18/Cereblon

YPEL1 YPEL3 YPEL2

6.51e-0582003IPR004910
DomainYippee-Mis18

YPEL1 YPEL3 YPEL2

6.51e-0582003PF03226
DomainZINC_FINGER_C2H2_2

ZNF765 ZNF266 WIZ ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF804B ZNF761 ZNF350 ZNF396 ZNF554

9.14e-0577520021PS50157
DomainZINC_FINGER_C2H2_1

ZNF765 ZNF266 WIZ ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF804B ZNF761 ZNF350 ZNF396 ZNF554

9.48e-0577720021PS00028
Domain-

ZNF765 ZNF266 ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF396 ZNF554

1.33e-04679200193.30.160.60
DomainKRAB

ZNF765 ZNF266 ZNF620 ZNF81 ZNF573 ZNF484 ZNF805 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF554

1.34e-0435820013PS50805
DomainZnf_C2H2

ZNF765 ZNF266 WIZ ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF804B ZNF761 ZNF350 ZNF396 ZNF554

1.55e-0480520021IPR007087
Domainzf-C2H2

ZNF765 ZNF266 ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF396 ZNF554

1.72e-0469320019PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF765 ZNF266 ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF396 ZNF554

1.75e-0469420019IPR013087
DomainKRAB

ZNF765 ZNF266 ZNF620 ZNF81 ZNF573 ZNF484 ZNF805 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF554

1.80e-0436920013SM00349
DomainKRAB

ZNF765 ZNF266 ZNF620 ZNF81 ZNF573 ZNF484 ZNF805 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF554

1.85e-0437020013IPR001909
DomainK_chnl_volt-dep_ELK

KCNH8 KCNH4

3.40e-0432002IPR003950
DomainUnc-13

UNC13C UNC13A

3.40e-0432002IPR027080
DomainKRAB

ZNF765 ZNF620 ZNF81 ZNF573 ZNF484 ZNF805 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF554

4.99e-0435820012PF01352
Domainzf-C2H2_6

ZNF765 ZNF266 ZNF660 ZNF620 ZSCAN2 ZNF573 ZNF329 ZNF805 ZNF8 ZNF761 ZNF554

5.93e-0431420011PF13912
DomainZF_DAG_PE_1

VAV1 UNC13C PRKCZ ARHGAP45 UNC13A

6.12e-04642005PS00479
DomainZF_DAG_PE_2

VAV1 UNC13C PRKCZ ARHGAP45 UNC13A

6.12e-04642005PS50081
DomainC1

VAV1 UNC13C PRKCZ ARHGAP45 UNC13A

6.57e-04652005SM00109
DomainCadherin_2

PCDH11X PCDHGB3 PCDH11Y PCDHB12 PCDHB11

6.57e-04652005PF08266
DomainCadherin_N

PCDH11X PCDHGB3 PCDH11Y PCDHB12 PCDHB11

6.57e-04652005IPR013164
DomainPE/DAG-bd

VAV1 UNC13C PRKCZ ARHGAP45 UNC13A

7.05e-04662005IPR002219
DomainNAP_family

TSPY2 TSPY8 TSPY10

7.36e-04172003IPR002164
DomainNAP

TSPY2 TSPY8 TSPY10

7.36e-04172003PF00956
DomainARM-type_fold

DOCK8 TTI2 RTTN ARFGEF1 RICTOR NBEA APOB ARMC9 MROH1 UPF2 XPOT

1.11e-0333920011IPR016024
DomainCH

SPEF2 ACTN4 VAV1 MICAL1 LMO7

1.12e-03732005PS50021
DomainMunc13_dom-2

UNC13C UNC13A

1.12e-0352002IPR014772
DomainMHD2

UNC13C UNC13A

1.12e-0352002PS51259
DomainProtocadherin

PCDH11X PCDH11Y

1.12e-0352002PF08374
DomainMunc13_subgr_dom-2

UNC13C UNC13A

1.12e-0352002IPR019558
DomainMembr_traf_MHD

UNC13C UNC13A

1.12e-0352002PF10540
DomainDMAP_binding

DIP2A DIP2B

1.12e-0352002PF06464
DomainDUF1041

UNC13C UNC13A

1.12e-0352002SM01145
DomainProtocadherin

PCDH11X PCDH11Y

1.12e-0352002IPR013585
DomainCH-domain

SPEF2 ACTN4 VAV1 MICAL1 LMO7

1.26e-03752005IPR001715
DomainDMAP1-bd

DIP2A DIP2B

1.66e-0362002IPR010506
DomainDMAP_binding

DIP2A DIP2B

1.66e-0362002SM01137
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYO6 LSG1 MAP3K20 ACTN4 ADAR DHX9 BLVRA VPS33B CKAP4 WDR1 VCL GPI TMEM201 WDR36 SMCHD1 RICTOR MTPAP SLC25A22 GTF2H1 UPF2 TRIM32 FANCI SMU1 EIF3B DHX34 ATP5F1A XPOT

6.27e-0813532112729467282
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MYO6 LSG1 BCLAF1 ARFIP2 DMXL1 DHX9 WIZ OSBPL9 GPI SHROOM3 WDR36 ANK3 ARFGEF1 MUC16 RICTOR NBEA APOB SLC39A14 ATP5F1A

3.25e-077772111935844135
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

ZNF266 MYO6 LYPLAL1 ORC3 CYP20A1 ACTN4 RFTN2 ADAR DIP2A VPS33B OSBPL9 ZSCAN2 IFT80 MGAT4C DIP2B CERT1 KCNH4 FANCI TTLL11 PRKCZ CSMD1 SEPTIN10 MINDY1 ATP5F1A

6.37e-0712422112430973865
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CENPE CSMD2 TMEM132B QRICH2 DHX9 DIP2A WIZ USP17L3 CHD6 CACNA1F APPBP2 PCDHGB3 TTI2 PCDHB12 NBEA ICE1 REV3L MTPAP

6.72e-077362111829676528
Pubmed

Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.

YPEL1 YPEL3 YPEL2

2.18e-065211315556292
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MYO6 ADCY1 BLVRA WIZ MME KIFC3 CKAP4 WDR1 FKBP5 VCL MVB12B GPI ARMC9 CUBN PRCP SNX18 SERPINB1 PRKCZ SLC5A8 ATP5F1A

4.40e-0610162112019056867
Pubmed

An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry.

MYO6 ACTN4 ICE1 LMO7 FANCI

6.25e-0643211530975701
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

LSG1 HSPA13 BLVRA GOLIM4 PISD CKAP4 GPI LRP12 SMCHD1 ARFGEF1 APOB DRAM2 MROH1 TMTC4 LMO7 FANCI CD38 SLC39A14 SEPTIN10 XPOT

8.31e-0610612112033845483
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

CENPE KIZ DHX9 PCDH11X CHD6 SHROOM3 SH3RF1 PCDH11Y LIFR ATP5F1A

8.33e-062772111030745168
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MYO6 LSG1 BCLAF1 MAP3K20 ACTN4 ADAR DHX9 ITPR3 PISD CKAP4 WDR1 WDR36 SMCHD1 MTPAP SLC25A22 GTF2H1 UPF2 LMO7 SMU1 EIF3B HSPA14 ATP5F1A

9.25e-0612572112236526897
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

HECW1 DHX9 CKAP4 VCL GTF2H1 EIF3B PRKCZ POLQ DHX34

2.42e-05250211933536335
Pubmed

YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.

YPEL1 YPEL3 YPEL2

2.56e-0510211320580816
Pubmed

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.

ACTN4 F13A1 WDR1 VCL

3.64e-0531211414630798
Pubmed

Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex.

ADCY1 PRKCZ

3.66e-052211221127255
Pubmed

A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro.

POLH REV3L

3.66e-052211227481099
Pubmed

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome.

ADAR DHX9

3.66e-052211228355180
Pubmed

DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions.

POLH REV3L

3.66e-052211222615128
Pubmed

Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.

PCDH11X PCDH11Y

3.66e-052211211003707
Pubmed

Pcdh11x Negatively Regulates Dendritic Branching.

PCDH11X PCDH11Y

3.66e-052211225687328
Pubmed

Mutant POLQ and POLZ/REV3L DNA polymerases may contribute to the favorable survival of patients with tumors with POLE mutations outside the exonuclease domain.

REV3L POLQ

3.66e-052211232838755
Pubmed

Juvenile bare: a new hair loss mutation on chromosome 7 of the mouse.

GPI OCA2

3.66e-05221129656467
Pubmed

PKC zeta controls DNA topoisomerase-dependent human caspase-2 pre-mRNA splicing.

CASP2 PRKCZ

3.66e-052211218166155
Pubmed

RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses.

VAV1 RASGRF2

3.66e-052211217923690
Pubmed

Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.

PCDH11X PCDH11Y

3.66e-052211222592879
Pubmed

Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.

CSMD2 CSMD1

3.66e-052211224408017
Pubmed

Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.

PCDH11X PCDH11Y

3.66e-052211214727141
Pubmed

Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.

PCDH11X PCDH11Y

3.66e-052211221276771
Pubmed

Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.

PCDH11X PCDH11Y

3.66e-052211216874762
Pubmed

PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.

PCDH11X PCDH11Y

3.66e-052211216825765
Pubmed

The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modern Homo sapiens.

PCDH11X PCDH11Y

3.66e-052211223600975
Pubmed

Role of protein kinase Czeta and its adaptor protein p62 in voltage-gated potassium channel modulation in pulmonary arteries.

GTF2H1 PRKCZ

3.66e-052211217699685
Pubmed

A comparative analysis of the pig, mouse, and human PCDHX genes.

PCDH11X PCDH11Y

3.66e-052211215112107
Pubmed

Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes.

HPCAL4 VSNL1

3.66e-052211210520747
Pubmed

Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains.

PCDH11X PCDH11Y

3.66e-052211222744706
Pubmed

Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities.

LIFR PRKCZ

3.66e-052211218566367
Pubmed

The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability.

POLH REV3L

3.66e-052211226727495
Pubmed

Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.

POLH POLQ

3.66e-052211218485835
Pubmed

Inverse Correlation of TRIM32 and Protein Kinase C ζ in T Helper Type 2-Biased Inflammation.

TRIM32 PRKCZ

3.66e-052211233096083
Pubmed

A genetic association study of CSMD1 and CSMD2 with cognitive function.

CSMD2 CSMD1

3.66e-052211227890662
Pubmed

Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS.

APOA5 APOB

3.66e-052211224694356
Pubmed

Suppression of gluconeogenic gene transcription by SIK1-induced ubiquitination and degradation of CRTC1.

SIK1 CRTC1

3.66e-052211229408765
Pubmed

Salt-inducible kinase 1-CREB-regulated transcription coactivator 1 signalling in the paraventricular nucleus of the hypothalamus plays a role in depression by regulating the hypothalamic-pituitary-adrenal axis.

SIK1 CRTC1

3.66e-052211236434056
Pubmed

Quantitative analysis of alternative transcripts of human PCDH11X/Y genes.

PCDH11X PCDH11Y

3.66e-052211219859901
Pubmed

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.

CSMD2 CSMD1

3.66e-052211221439553
Pubmed

Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells.

ADAR DHX9

3.66e-052211238530197
Pubmed

DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.

POLH POLQ

3.66e-052211217449470
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

CYP17A1 ACTN4 F13A1 VPS33B ZBTB40 SOST ANK3 HIPK2 CRTC1 RICTOR SALL4 APOB CUBN MKX RNF38 PRKCZ MINDY1 ATP5F1A XPOT

3.80e-0510842111911544199
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

MAP3K20 DENND2B SHROOM3 RICTOR LMO7 TRIM32

3.85e-05102211615778465
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

MYO6 BCLAF1 ACTN4 DHX9 VCL GPI SHROOM3 LMO7 TRIM32 ZNF804B EIF3B ATP5F1A

3.91e-054772111231300519
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

REPS1 MYO6 ACTN4 HSPA13 DIP2A WIZ ZNF660 CHD6 KIFC3 YPEL3 VSNL1 ANK3 ZNF329 NBEA REV3L LMO7 TRIM32 RNF38 ZNF350 ATP5F1A XPOT

4.05e-0512852112135914814
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KCNH8 MYO6 MAPKAPK2 KIZ MAEA WDR25 ADCY1 DENND2B OSBPL9 PISD CHD6 MME FKBP5 DIP2B SHROOM3 ANK3 PCDH11Y HIPK2 CERT1 ZNF248 TTLL11 PRKCZ CSMD1

4.10e-0514892112328611215
Pubmed

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.

CSMD2 TMEM132B TMEM200A ABCA5 CSMD1

4.14e-0563211511572484
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

NUP50 REPS1 MYO6 ORC3 ADAR VPS33B GOLIM4 WDR1 WDR36 TRIM32 FANCI ATP5F1A XPOT

4.25e-055602111335241646
Pubmed

A human MAP kinase interactome.

MYO6 ACTN4 MAP3K5 RTKN2 CHD6 SH3RF1 ANK3 HIPK2 LAMA4 CRTC1 BICRAL PRKCZ

4.67e-054862111220936779
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

REPS1 MAPKAPK2 MAEA MAP3K5 ITPR3 DIP2A WIZ KIFC3 RAD9A MVB12B SHROOM3 SH3RF1 RTTN ICE1 REV3L SLC25A22 MROH1 FANCI DHX34

4.90e-0511052111935748872
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF765 ORC3 LSG1 BCLAF1 CYP20A1 ACTN4 PTGFRN DHX9 GOLIM4 CKAP4 WDR1 GPI TMEM201 WDR36 ATN1 ZNF329 MTPAP FANCI SLC39A14 XPOT

4.92e-0512032112029180619
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

BCLAF1 ACTN4 ADAR DHX9 ITPR3 CKAP4 TMEM201 WDR36 SMCHD1 APOB LMO7 FANCI SMU1 ATP5F1A

5.01e-056522111431180492
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

CYP17A1 RTKN2 VCL NRAP ANK3 CUBN MTPAP ZNF248 UPF2 TLL2 HSPA14

5.16e-054152111116385451
Pubmed

Genome-wide association study of antibody response to smallpox vaccine.

SNX18 MKX UNC13C CSMD1

5.29e-0534211422542470
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NUP50 MYO6 LSG1 BCLAF1 ACTN4 ADAR DHX9 VPS33B CKAP4 VCL GPI TMEM201 WDR36 SMCHD1 ZNF329 APOB SLC25A22 FANCI SMU1 EIF3B ATP5F1A XPOT

6.12e-0514252112230948266
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

ADAR DHX9 WIZ FKBP5 SMCHD1 HIPK2 SMU1 XPOT

6.41e-05220211835785414
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

ACTN4 DHX9 VCL TRIM32 EIF3B ATP5F1A XPOT

7.35e-05166211735687106
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

MYO6 LSG1 BCLAF1 MAP3K20 ACTN4 ADAR DENND2B DHX9 ITPR3 CKAP4 WDR1 WDR36 APOB SLC25A22 LMO7 EIF3B ATP5F1A

7.55e-059492111736574265
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDH11X PCDHGB3 PCDH11Y PCDHB12 PCDHB11

8.99e-0574211510817752
Pubmed

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

MYO6 ZBTB40 HPCAL4 MICAL1 ANK3 APOB SLC25A22 UNC13A

9.56e-05233211829518331
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

BCLAF1 ST6GAL2 IFT80 SHROOM3 SMCHD1 CRTC1 ICE1 ABCA5 LMO7 IGSF1 DHX34 MINDY1

1.04e-045292111214621295
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

MYO6 ADAR PTGFRN DHX9 TMEM201 SMCHD1 SLC25A22 LIFR PRCP SERPINB1 EIF3B ATP5F1A XPOT

1.05e-046132111322268729
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDH11X PCDHGB3 PCDH11Y PCDHB12 PCDHB11

1.09e-0477211510835267
Pubmed

Salt-inducible kinase 1 regulates bone anabolism via the CRTC1-CREB-Id1 axis.

SIK1 CRTC1

1.09e-043211231672960
Pubmed

Identification of two new members of the CSMD gene family.

CSMD2 CSMD1

1.09e-043211212906867
Pubmed

Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells.

POLH REV3L

1.09e-043211232721818
Pubmed

CircZFR promotes colorectal cancer progression via stabilizing BCLAF1 and regulating the miR-3127-5p/RTKN2 axis.

BCLAF1 RTKN2

1.09e-043211238805063
Pubmed

CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.

DIP2A DIP2B

1.09e-043211217236128
Pubmed

Hydrocephalus with hop gait (hyh): a new mutation on chromosome 7 in the mouse.

GPI OCA2

1.09e-04321122364541
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13C UNC13A

1.09e-043211233105896
Pubmed

The scaffold protein POSH regulates axon outgrowth.

SHROOM3 SH3RF1

1.09e-043211218829867
Pubmed

Cadherin expression in the somatosensory cortex: evidence for a combinatorial molecular code at the single-cell level.

PCDH11X PCDH11Y

1.09e-043211221129452
Pubmed

TORC-SIK cascade regulates CREB activity through the basic leucine zipper domain.

SIK1 CRTC1

1.09e-043211217565599
Pubmed

POSH is an intracellular signal transducer for the axon outgrowth inhibitor Nogo66.

SHROOM3 SH3RF1

1.09e-043211220926658
Pubmed

Genetic variation for prolidase (PEP-4) in the mouse maps near the gene for glucosephosphate isomerase (GPI-1) on chromosome 7.

GPI OCA2

1.09e-04321127295293
Pubmed

Human biliverdin reductase suppresses Goodpasture antigen-binding protein (GPBP) kinase activity: the reductase regulates tumor necrosis factor-alpha-NF-kappaB-dependent GPBP expression.

BLVRA CERT1

1.09e-043211220177069
Pubmed

Mechanisms of accurate translesion synthesis by human DNA polymerase eta.

POLH REV3L

1.09e-043211210856253
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13C UNC13A

1.09e-043211223658173
Pubmed

CD10, p63 and CD99 expression in the differential diagnosis of atypical fibroxanthoma, spindle cell squamous cell carcinoma and desmoplastic melanoma.

MME CKAP4

1.09e-043211220184665
Pubmed

HECW1 induces NCOA4-regulated ferroptosis in glioma through the ubiquitination and degradation of ZNF350.

HECW1 ZNF350

1.09e-043211238049396
Pubmed

Dietary fat and apolipoprotein genotypes modulate plasma lipoprotein levels in Brazilian elderly women.

APOA5 APOB

1.09e-043211219915960
Pubmed

Distribution and functional properties of human KCNH8 (Elk1) potassium channels.

KCNH8 KCNH4

1.09e-043211212890647
Pubmed

Where and what is the right shift factor or cerebral dominance gene? A critique of Francks et al. (2007).

PCDH11X PCDH11Y

1.09e-043211219125366
Pubmed

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells.

POLH REV3L

1.09e-043211227095204
Pubmed

Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.

APOA5 APOB

1.09e-043211218078817
Pubmed

The CRTC1-SIK1 pathway regulates entrainment of the circadian clock.

SIK1 CRTC1

1.09e-043211223993098
Pubmed

Glucose phosphate isomerase enzyme-activity mutants in Mus musculus: genetical and biochemical characterization.

GPI OCA2

1.09e-04321122344351
Pubmed

Lipopolysaccharide-induced biphasic inositol 1,4,5-trisphosphate response and tyrosine phosphorylation of 140-kilodalton protein in mouse peritoneal macrophages.

PTAFR ITPR3

1.09e-04321129013981
Pubmed

Non-clustered protocadherin.

PCDH11X PCDH11Y

1.09e-043211221173574
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13C UNC13A

1.09e-043211222966208
Pubmed

Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links.

POLH REV3L

1.09e-043211220028736
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13C UNC13A

1.09e-043211215988013
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

MYO6 LYPLAL1 ADAR DHX9 BLVRA VPS33B WDR1 FKBP5 MTPAP SLC25A22 UPF2 SMU1 HSPA14 ATP5F1A

1.13e-047042111429955894
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDH11X PCDHGB3 PCDH11Y PCDHB12 PCDHB11

1.30e-0480211510716726
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

NUP50 LYPLAL1 ACTN4 ADAR DHX9 HSPA13 BLVRA GOLIM4 PISD CKAP4 SMCHD1 APOB MTPAP SLC25A22 TRIM32 PRCP SERPINB1 SLC39A14 ATP5F1A XPOT

1.36e-0412972112033545068
InteractionTSPY8 interactions

TSPY3 TSPY2 TSPY8

1.07e-0632073int:TSPY8
CytobandYp11.2

TSPY3 TSPY2 TSPY1 PCDH11Y TSPY8 TSPY10

5.24e-06942126Yp11.2
CytobandEnsembl 112 genes in cytogenetic band chrYp11

TSPY3 TSPY2 TSPY1 PCDH11Y TSPY8 TSPY10

7.43e-051502126chrYp11
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF765 ZNF266 WIZ ZNF660 ZBTB40 ZNF620 ZSCAN2 ZNF81 ZNF573 ZNF484 ZNF329 ZNF805 SALL4 ZNF248 ZNF2 ZNF8 ZNF761 ZNF350 ZNF396 ZNF554

1.21e-067181452028
GeneFamilyYippee like family

YPEL1 YPEL3 YPEL2

4.99e-06514531130
GeneFamilyUNC13 homologs

UNC13C UNC13A

3.79e-0441452836
GeneFamilyWD repeat domain containing

WDR25 DMXL1 IFT80 WDR1 WDR36 DCAF8L2 NBEA SMU1

1.26e-032621458362
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

KCNH8 CSMD2 TMEM132B ADCY1 ST6GAL2 AMER2 PCDH11X MGAT4C HPCAL4 PDE11A MVB12B DIP2B LRP12 VSNL1 ANK3 YPEL2 ARFGEF1 RICTOR SALL4 NBEA REV3L CERT1 ZNF248 ANKRD36B SLC25A22 LRRN3 PRKCZ CSMD1 UNC13A

1.84e-08110620929M39071
CoexpressionZHONG_PFC_C4_PTGDS_POS_OPC

PCDH11X OSBPL9 GOLIM4 MVB12B ANK3 PCDH11Y RICTOR MTPAP LRRN3 TMTC4

3.08e-0714720910M39099
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

HECW1 MYO6 SPEF2 AK9 CSMD2 CHD6 MME KIFC3 FKBP5 DIP2B CUBN UPF2 ZNF804B CSMD1

7.19e-0641720914M39224
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ANKRD36C TESPA1 DIP2B ZNF573 ANK3 SMCHD1 YPEL2 CRTC1 ANKRD36B LRRN3 LMO7

2.68e-0919521211d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN ST6GAL2 OTOGL PCDH11X MME MGAT4C PCDH11Y PTCHD4 ZNF804B UNC13C

9.61e-091702121049fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 PTGFRN ST6GAL2 OTOGL MME MGAT4C PTCHD4 ZNF804B UNC13C

1.53e-0717321298335b77f730ed43fc348a005566e73a103c6774b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OTOGL PCDH11X CACNA1F SALL4 APOB TEX11 UNC13C CSMD1

2.59e-0718421292cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OTOGL PCDH11X CACNA1F SALL4 APOB TEX11 UNC13C CSMD1

2.59e-0718421292b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 OTOGL PCDH11X CACNA1F SALL4 APOB TEX11 UNC13C CSMD1

2.59e-071842129ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ANKRD36C TMEM200A HSPA13 ZBTB40 IFT80 WDR36 DOCK8 SMCHD1 POLQ

2.84e-0718621298571956890fc9894d766ba294a28e376b4aba428
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ORC3 ANKRD36C TESPA1 RTKN2 HPCAL4 ANK3 CRTC1 LRRN3 LMO7

3.10e-071882129b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CSMD2 RTKN2 PCDH11X IFT80 KIFC3 CACNA1F SHROOM3 LMO7 DSEL

4.60e-071972129b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

SIK1 RTKN2 IFT80 KIFC3 MICAL1 SALL4 LMO7 PRKCZ DSEL

4.80e-07198212985f424cd9bb3117c9e322031024aabb87696ce47
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X GOLIM4 APOA5 LAMA4 TMTC4 UNC13C IGSF1

1.33e-061152127ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN ST6GAL2 OTOGL MME MGAT4C PTCHD4 ZNF804B UNC13C

1.48e-0616821281d58731a481ecac84c15affa84f8041dd67d944c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN ST6GAL2 OTOGL PCDH11X MME MGAT4C PTCHD4 ZNF804B

1.69e-0617121289d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN F13A1 OTOGL SEMA4A OCA2 TMTC4 MKX UNC13C

1.93e-0617421282947e5906b172d149412fa4e77476fce4ea695d2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN ST6GAL2 OTOGL PCDH11X MME MGAT4C PTCHD4 ZNF804B

2.01e-061752128d4827b4dfad07f11cbdd47fbed287af1afb9b1b8
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36C ANK3 MUC16 SALL4 NBEA ANKRD36B LMO7 SLC5A8

2.38e-0617921286e965e424eebef50f0202cff75f458be395cfca1
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

TMEM200A HSPA13 ZBTB40 IFT80 WDR36 DOCK8 SMCHD1 POLQ

3.04e-061852128a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 MME KIFC3 FKBP5 RTTN CUBN ZNF804B SLC39A14

3.17e-0618621285784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

DLGAP2 MYO6 MAP3K5 SH3RF1 ANK3 RTTN PTCHD4 TLL2

3.43e-061882128b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2B PCDH11X MME FAM110B RASGRF2 PCDH11Y TLL2 UNC13C

4.16e-061932128c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CSMD2 ADCY1 OTOGL MME YPEL3 SHROOM3 MUC16 CSMD1

4.49e-06195212819853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CSMD2 ADCY1 OTOGL MME YPEL3 SHROOM3 MUC16 CSMD1

4.49e-061952128d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 HECW1 TMEM132B VSNL1 NBEA ANKRD36B ABCA5 CSMD1

4.66e-061962128676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANKRD36C DIP2A ANK3 SMCHD1 RTTN ARFGEF1 RICTOR ABCA5

5.22e-061992128f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

PCDH11X ANK3 PCDH11Y NBEA LRRN3 LMO7 UNC13C ATP5F1A

5.22e-0619921281b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RTKN2 PCDH11X IFT80 KIFC3 CACNA1F SALL4 LMO7 DSEL

5.22e-061992128a270630626df614f8605abddb7dee7c4d74f6149
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

PCDH11X ANK3 PCDH11Y NBEA LRRN3 LMO7 UNC13C ATP5F1A

5.22e-0619921284bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SIK1 RTKN2 IFT80 KIFC3 CACNA1F SALL4 LMO7 DSEL

5.41e-062002128ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ZBTB40 CHD6 MVB12B CASP2 ZNF248 TTLL11

1.18e-05160212750d4f867d021abcfeb49e6812bcfd5bb57466a31
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ZBTB40 CHD6 MVB12B CASP2 ZNF248 TTLL11

1.18e-0516021270f15f895f11dcabb73df79b26bfc4947f38435a7
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CENPE ZBTB40 CHD6 MVB12B CASP2 ZNF248 TTLL11

1.18e-0516021277d004bfe42707605b3851cb2319126acda4d4802
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36C ZNF620 YPEL3 VSNL1 SH3RF1 CASP2 SLC5A8

1.23e-0516121279cfbbcd38ec2e75376bbc26001964b6991ad0e21
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

RFTN2 MAP3K5 AMER2 MGAT4C HIPK2 CD38 MKX

1.23e-051612127347edb0de10850b7d16c40945751033289289c9b
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 ADCY1 HPCAL4 VSNL1 ZDBF2 ZNF804B MKX

1.45e-0516521276d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 ADCY1 HPCAL4 VSNL1 ZDBF2 ZNF804B MKX

1.45e-05165212702cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HECW1 NUP210L CSMD2 MME CUBN CSMD1 UNC13A

1.56e-0516721273edb0570e583bb527165bcd8a4c25a042054043b
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

MYO6 RTKN2 SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ

1.75e-051702127e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN ST6GAL2 OTOGL GOLIM4 MGAT4C SHROOM3 UNC13C

1.75e-0517021273174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTGFRN F13A1 SEMA4A OCA2 TMTC4 MKX UNC13C

1.89e-05172212792e76cbf4807704790f42cf2507e92f85cd3bc92
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RTKN2 KIFC3 SHROOM3 ANK3 POLH LMO7 PRKCZ

1.96e-051732127b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BEST3 CSMD2 ST6GAL2 PDE11A PCDHB12 LAMA4 UNC13C

2.04e-051742127cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BEST3 CSMD2 ST6GAL2 PDE11A PCDHB12 LAMA4 UNC13C

2.04e-051742127b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BEST3 CSMD2 ST6GAL2 PDE11A PCDHB12 LAMA4 UNC13C

2.04e-05174212771730503be3d9c839c4c9e950145e2101d682a1c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMEM200A ST6GAL2 RTKN2 OTOGL GOLIM4 SHROOM3 UNC13C

2.04e-051742127ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

BEST3 CSMD2 ST6GAL2 PDE11A PCDHB12 LAMA4 UNC13C

2.04e-051742127ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE FAM217A ZSCAN2 LRP12 LAMA4 ZNF8 PRKCZ

2.11e-05175212709163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPE FAM217A ZSCAN2 LRP12 LAMA4 ZNF8 PRKCZ

2.11e-0517521270801cccec6915aefc135262fc74580280fd51aa5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY1 FAM110B MVB12B LRRC9 PLPP3 UNC13C MINDY1

2.19e-0517621276c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TESPA1 TMEM200A ST6GAL2 RTKN2 OTOGL SHROOM3 UNC13C

2.19e-05176212740993c41c1017b53039a337174fc56632b278609
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAP3K5 RTKN2 IFT80 KIFC3 SHROOM3 LMO7 PRKCZ

2.27e-0517721279af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPE ZSCAN2 FAM110B RICTOR THBS2 DSEL POLQ

2.36e-051782127c87945146b2734141f07b39d268e0d8086ee0364
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_atypical-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF765 MYO6 DMXL1 HSPA13 WIZ POLH ABCA5

2.44e-0517921275be883d7d0be3180bb9844e4a757f0dd247294e4
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP20A1 ADCY1 ZBTB40 MVB12B ANK3 ZNF8 CSMD1

2.53e-051802127da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP20A1 ADCY1 ZBTB40 MVB12B ANK3 ZNF8 CSMD1

2.53e-05180212750758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP20A1 ADCY1 ZBTB40 MVB12B ANK3 ZNF8 CSMD1

2.53e-0518021275b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCellMesenchymal_cells-Adipo-CAR|Mesenchymal_cells / Lineage and Cell class

DENND2B MME SHROOM3 LIFR PLPP3 LMO7 CSMD1

2.62e-0518121271cfb03eb03a37b036b4eeacec69c9b8163af1ee4
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

MYO6 SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ SLC5A8

2.81e-0518321278e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellCOVID-CD4-CD8_1|COVID / Condition, Cell_class and T cell subcluster

TRAV8-6 CENPE IFT80 RASGRF2 ZDBF2 CD38 PRKCZ

3.02e-051852127c634bb04a081ae3214b68f6e4a147db5b2b916ed
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RTKN2 VAV1 NRAP SALL4 TLL2

3.12e-05762125254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RTKN2 VAV1 NRAP SALL4 TLL2

3.12e-05762125efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 HECW1 TESPA1 OTOGL VSNL1 MKX UNC13C

3.12e-051862127bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

DENND2B MME SHROOM3 LIFR PLPP3 LMO7 CSMD1

3.12e-0518621276ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X MME THBS2 TMTC4 MKX UNC13C

3.14e-051262126a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH11X GOLIM4 ZNF484 LAMA4 TMTC4 UNC13C

3.14e-05126212694bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPE F13A1 VAV1 FANCI CD38 POLQ ARHGAP45

3.23e-05187212773931a5ea73799095daff100b5f18853c57c74dc
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

MYO6 RTKN2 SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ

3.34e-051882127707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellIPF-Epithelial-Club|IPF / Disease state, Lineage and Cell class

MYO6 SHROOM3 SH3RF1 ANK3 PTCHD4 LMO7 PRKCZ

3.46e-051892127f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACTN4 RTKN2 VCL SHROOM3 SH3RF1 LMO7 PRKCZ

3.58e-05190212730b50d183d7649146eb1e79b47ba897355f1998a
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HSPA13 CKAP4 SEMA4A HIPK2 CD38 SEPTIN10 ATP5F1A

3.70e-0519121273df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SPEF2 RTKN2 SHROOM3 NRAP SALL4 SERPINB1

3.74e-0513021260a6b87635e650df431a88f2e6396abead84d901d
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

MYO6 DENND2B SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ

3.82e-051922127efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSBPL9 FKBP5 HIPK2 CERT1 LIFR CD38 ARHGAP45

3.82e-0519221271ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 HECW1 TMEM200A HPCAL4 VSNL1 ZDBF2 RTL1

3.95e-051932127461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2B PCDH11X MGAT4C FAM110B RASGRF2 PCDH11Y TLL2

3.95e-0519321272189da4b727e25e62669d7b9257f06493be21a27
ToppCellControl-CD8+_T_naive|Control / Disease condition and Cell class

TESPA1 FKBP5 RASGRF2 NBEA LRRN3 LMO7 DSEL

3.95e-051932127627d345baf1940218c61907305705298e473dbab
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2B PCDH11X MGAT4C FAM110B RASGRF2 PCDH11Y TLL2

3.95e-0519321273ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

PTAFR MME FKBP5 DOCK8 HIPK2 CERT1 PLPP3

3.95e-051932127cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 HECW1 TMEM200A HPCAL4 VSNL1 ZDBF2 RTL1

3.95e-0519321270dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 KIFC3 SHROOM3 SH3RF1 ANK3 CUBN LMO7

3.95e-0519321273866667dd221612589ae50f5c52f73a183a49ce6
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRAV8-6 TRAV3 CENPE TESPA1 FANCI POLQ TRAV27

3.95e-051932127bec113472c40c0106a9427248cbcf54548797596
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2B PCDH11X MGAT4C FAM110B RASGRF2 PCDH11Y TLL2

3.95e-051932127658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO6 ITPR3 SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ

3.95e-051932127a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BEST3 SIK1 PDE11A MUC16 PTCHD4 UNC13C UNC13A

4.08e-051942127d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2B PCDH11X MGAT4C FAM110B RASGRF2 PCDH11Y UNC13C

4.08e-05194212783863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO6 RTKN2 SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ

4.08e-05194212753f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO6 RTKN2 SHROOM3 SH3RF1 ANK3 LMO7 PRKCZ

4.22e-0519521279406866f99555198a9be311fbd65751b70f35446
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ANKRD36C TESPA1 RTKN2 HPCAL4 ANK3 SMCHD1 LRRN3

4.22e-05195212722191d361af136942508f1553ff41a626ed982ad
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

PTAFR F13A1 CKAP4 FKBP5 SERPINB1 ARHGAP45 ATP5F1A

4.36e-051962127f245e929a286cb097130572e1027b4f01be8b04d
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

ADCY1 VSNL1 ANK3 PCDH11Y NBEA LMO7 UNC13C

4.50e-05197212779b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

ADCY1 VSNL1 ANK3 PCDH11Y NBEA LMO7 UNC13C

4.50e-051972127d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

MME CACNA1F ATN1 ANK3 ABCA5 LMO7 DSEL

4.50e-0519721271a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-20|World / Primary Cells by Cluster

MYO6 TMEM132B DENND2B SHROOM3 LIFR THBS2 PLPP3

4.64e-051982127bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

RFTN2 TESPA1 CHD6 HPCAL4 RASGRF2 SMCHD1 LRRN3

4.64e-051982127ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 HECW1 TMEM132B VSNL1 NBEA ABCA5 CSMD1

4.64e-051982127c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 HECW1 TMEM132B VSNL1 NBEA ABCA5 CSMD1

4.64e-0519821276d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 HECW1 PCDH11X VSNL1 NBEA CSMD1 UNC13A

4.64e-0519821278ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 HECW1 TMEM132B VSNL1 NBEA ABCA5 CSMD1

4.64e-0519821274ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 ANK3 NBEA ANKRD36B ABCA5 CSMD1

4.64e-0519821270ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPI REV3L LIFR LRRN3 PLPP3 PRCP ATP5F1A

4.79e-051992127a900ef002e1ae583b70be0253d8c44dae6754916
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1|Neuronal / cells hierarchy compared to all cells using T-Statistic

PTGFRN ST6GAL2 OTOGL GOLIM4 MME MGAT4C UNC13C

4.95e-052002127e0eccfdef3a1b4ffb47e7496764c7cf339618d39
DiseaseEarly myoclonic encephalopathy

SIK1 SLC25A22

4.66e-0522022C0270855
Diseasegallbladder cancer (is_implicated_in)

CYP17A1 RICTOR APOB

8.59e-05132023DOID:3121 (is_implicated_in)
DiseaseEarly myoclonic encephalopathy

SIK1 SLC25A22

1.39e-0432022cv:C0270855
DiseaseColorectal Carcinoma

AMER2 ODAM PCDH11X FAM110B RASGRF2 ARFGEF1 APOB CUBN KCNH4 LIFR ABCA5 LMO7 PRKCZ DSEL

3.68e-0470220214C0009402
Diseaseosteoarthritis biomarker measurement

CRTC1 CSMD1

6.87e-0462022EFO_0005890
Diseasecerebellum cortex volume change measurement, age at assessment

MVB12B CRTC1 CSMD1

7.32e-04262023EFO_0008007, EFO_0021497
Diseaseeosinophilic esophagitis

WDR25 SHROOM3 WDR36 SH3RF1 POLH PLPP3

9.31e-041632026EFO_0004232
DiseaseCone-Rod Dystrophy 2

SEMA4A CACNA1F DRAM2

1.01e-03292023C3489532
DiseaseIntellectual Disability

ZBTB40 PISD ATN1 DOCK8 TTI2 RTTN CASP2 NBEA ARMC9 CERT1

1.09e-0344720210C3714756
Diseasefemale breast cancer (is_implicated_in)

POLH FANCI

1.27e-0382022DOID:0050671 (is_implicated_in)
Diseasethiamine measurement

GOLIM4 CRTC1

2.02e-03102022EFO_0010540
Diseaseresponse to carboplatin, response to antineoplastic agent

SPEF2 CSMD1

2.02e-03102022GO_0097327, GO_0097328
Diseaseeye color

SIK1 MUC16 OCA2 CSMD1

3.44e-03902024EFO_0003949
Diseaseinterleukin 6 receptor subunit alpha measurement

NUP210L ADAR

3.46e-03132022EFO_0008187
DiseaseCakut

VPS33B LIFR

3.46e-03132022C1968949
DiseaseProteinuria

CUBN UNC13C

4.62e-03152022HP_0000093
DiseaseHypertriglyceridemia

APOA5 APOB

4.62e-03152022C0020557
Diseasegastroesophageal reflux disease

MVB12B CRTC1 APOB CSMD1

5.19e-031012024EFO_0003948
Diseaseamygdala volume change measurement

ZNF804B CSMD1

5.25e-03162022EFO_0021490
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SIK1 SLC25A22

5.25e-03162022C0393706
Diseasehealth literacy measurement

DLGAP2 SLC5A8 CSMD1

5.76e-03532023EFO_0010104
Diseasephosphatidylcholine 40:6 measurement

TMTC4 CSMD1

5.93e-03172022EFO_0010389
DiseaseSmall cell carcinoma of lung

BCLAF1 ADCY1 ZDBF2

6.07e-03542023C0149925
Diseaseesophageal adenocarcinoma, digestive system disease, Barrett's esophagus

GOLIM4 CRTC1

6.64e-03182022EFO_0000280, EFO_0000405, EFO_0000478
Diseaseesophageal adenocarcinoma

HECW1 CRTC1

6.64e-03182022EFO_0000478
Diseaseovarian cancer (is_implicated_in)

MYO6 MUC16 APOB

6.71e-03562023DOID:2394 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
NVSASDRFAASNFGK

UNC13A

916

Q9UPW8
HLEDFNEGASFSNLT

ABCA5

376

Q8WWZ7
SSKVANATFFGFHRL

BEST3

6

Q8N1M1
HSFFSLLKKNGRSEN

AMER2

161

Q8N7J2
DKQHTFRVNLFTDFD

EIF3B

256

P55884
SDSNHRRKGFNAQFQ

CSMD1

296

Q96PZ7
LEFQTDHSTGKRGFN

CSMD2

666

Q7Z408
KRGFNITFTTFRHNE

CSMD2

676

Q7Z408
GGFRHSEAFEALQQK

CKAP4

391

Q07065
DHQNSENVKLFSAFS

SSX2IP

486

Q9Y2D8
LLESHRFAKAFNSNN

ARFGEF1

1686

Q9Y6D6
SQSARFNKHLDRGFN

ATN1

761

P54259
HAFSGAQKAETAANR

ACTN4

266

O43707
HSAFAPEFQQTDSGK

APOA5

321

Q6Q788
TEDKGLQFGSSFQRH

DLGAP2

791

Q9P1A6
QHALGDAFADLSQKS

ARFIP2

161

P53365
SSGKFDNALFHAERA

APPBP2

346

Q92624
SHSSKRDQELAFQGT

ANKRD36B

1056

Q8N2N9
HRKSQSRKSFEFEDA

DENND2B

441

P78524
FSLLGKQRFEHSAAF

DMXL1

1686

Q9Y485
LGSSFIAARNFHASN

ATP5F1A

26

P25705
ENAFTVGTDNFQRHA

C17orf113

61

A0A1B0GUU1
FDKNSTFGSVEVHNL

CD38

216

P28907
QQESTFLFHGNKTED

NUP50

231

Q9UKX7
QEFASFLTKGRSHSS

OCA2

66

Q04671
LHQSSTFQFKSDSDR

QRICH2

161

Q9H0J4
FGVRKTHNLSFQDCE

RAD9A

116

Q99638
KEGRLAQHNSFSGFS

RFTN2

461

Q52LD8
SKVSDFFDQSSFLHN

ITPR3

2166

Q14573
TVDQKTFHFQARDAD

OSBPL9

71

Q96SU4
DHNRIRSFNDSAFAK

LRRC9

1256

Q6ZRR7
RSDGDFLHSTNGNKE

CERT1

211

Q9Y5P4
SHSSKRDQELAFQGT

ANKRD36C

1481

Q5JPF3
KFNFDQTHTKRSTFD

CACNA1F

681

O60840
LSNGKKFDSSHDRNE

FKBP5

61

Q13451
FFSALDKQHNEEQSG

FANCI

236

Q9NVI1
HTFKDLSNFSGAINV

MGAT4C

71

Q9UBM8
ALDNDSLFVNGFTHR

MUC16

13741

Q8WXI7
RAGHNNANAFDTKGS

HIPK2

941

Q9H2X6
LQLFGQDFSHAARSA

ARHGAP45

756

Q92619
QHAFRTFDKNGDGTI

HPCAL4

66

Q9UM19
FHSDDNISRKGFRLA

LRP12

141

Q9Y561
ARKHFSQAEGSQLDE

MAEA

221

Q7L5Y9
TDFGFAKETTSHNSL

MAPKAPK2

206

P49137
ANRDDRQSNTTKFGH

LSG1

256

Q9H089
RQSNTTKFGHSSFDQ

LSG1

261

Q9H089
TQRFKNGLFSSHADE

ENTPD7

456

Q9NQZ7
KDFAKSRSQFHSSTD

NRAP

1591

Q86VF7
QGKSFFVDHNSRATT

HECW1

1031

Q76N89
HISSSIRDGDSFAQK

ARMC9

81

Q7Z3E5
EIATSNSSANFKGFR

MFI

251

Q8NCR3
FESGHTNNVFQAKFL

DCAF8L2

266

P0C7V8
RQRNHSGSFSSNEFE

MKX

246

Q8IYA7
LDHRGTNNAFQAKSG

PDE11A

706

Q9HCR9
QSEGHNIFANLSSKE

PDE11A

746

Q9HCR9
NFQKTTLFAAHVSGA

DRAM2

111

Q6UX65
ANDFFRHQLSKDGQK

SLC25A22

86

Q9H936
ITHGFDDNGRNFNKD

MME

586

P08473
QKEAINFRHDSAGVF

ODAM

226

A1E959
ETLQADHFNTRLSFG

DIP2B

1411

Q9P265
DHFNTRLSFGDAAQT

DIP2B

1416

Q9P265
FGDNSFKDSRHLNFL

PRCP

131

P42785
FKDSRHLNFLTSEQA

PRCP

136

P42785
AKEGELSVFFRNNHF

MINDY1

306

Q8N5J2
RFDGTHSNFLLANAQ

KCNH4

21

Q9UQ05
NGIHDESNAFESKAS

LMO7

1171

Q8WWI1
GKDFKLSITFRNNSH

F13A1

531

P00488
QRFTRAAADFATHGK

MICAL1

331

Q8TDZ2
DANKDRFNHFSLTLN

GPI

31

P06744
AASHSSNTEFKFLNI

PCDHGB3

756

Q9Y5G1
ADIGENAKIHFSFSN

PCDH11X

276

Q9BZA7
DETRNLSAHKISGNF

MTPAP

251

Q9NVV4
NRFQKTDASVSHLSG

KIZ

581

Q2M2Z5
STQAGSFHFTRKAEL

MROH1

806

Q8NDA8
NDLKFTKNFGTENHR

RICTOR

1181

Q6R327
FTRSFSKENSHLGNV

MVB12B

96

Q9H7P6
FSHASEDIRKTFEIN

PCDHB12

281

Q9Y5F1
TGNSFQLPHKREFSE

INSL5

61

Q9Y5Q6
FSHASEDIRKTFEIN

PCDHB11

281

Q9Y5F2
KQGEDFSRTFNDHKQ

GOLIM4

141

O00461
DSSVTRAGFNASFHK

CUBN

2076

O60494
ERNSFLKTHNIETFF

ADCY1

461

Q08828
TNGRFREHNAKFSLD

APOB

1686

P04114
QFRSVSGNSADFLLH

IGSF1

916

Q8N6C5
QAESFVLTSSDGKFH

IFT80

76

Q9P2H3
FSSAFCRKHGETQDT

ICE1

1071

Q9Y2F5
ETQFGRSDQHGSKAS

BICRAL

836

Q6AI39
DLNSDQFKGFLRAHT

DOCK8

306

Q8NF50
RSHGFAAEFKLVDQS

ADAR

736

P55265
SNGAALAAQIHKESF

CHD6

2151

Q8TD26
ESFSSGSQDVHQKRV

CRTC1

166

Q6UUV9
LADQGKSFATASHRN

BCLAF1

416

Q9NYF8
KSFATASHRNTEEEG

BCLAF1

421

Q9NYF8
SKSEGQHENFLNISR

POLQ

1276

O75417
SNNRKGIAFADSGAH

CYP17A1

106

P05093
FNTASGRNKAFSLHV

IFIT1B

191

Q5T764
SGTRSFADENNVFHD

ANK3

4181

Q12955
NHRQSTTFRKKLDFG

CFAP97D1

16

B2RV13
NRYLSFHFKSGSLEN

BLVRA

226

P53004
NFSSLHLNSRDSGFS

MAP3K20

646

Q9NYL2
RNHQDVAGVFALSSF

LYPLAL1

136

Q5VWZ2
FGNHAKTESGVQREN

FAM110B

101

Q8TC76
DKLSSADDHRVNSGF

HSPA13

331

P48723
TRGNTAAQLSKTFHF

SERPINB1

46

P30740
ERKGRNFSQHIFIDS

CYP20A1

241

Q6UW02
KRDRSASGNSGFQHE

CUZD1

541

Q86UP6
ADHFSARLSFGDTQT

DIP2A

1411

Q14689
GDFFKNRNEIHVSSC

FAM217A

156

Q8IXS0
DAFNSSRKDSDQIFH

DHX34

816

Q14147
GKNFSSASALQIHER

SALL4

876

Q9UJQ4
DLFTAHNFSEQSRIG

SLC39A14

96

Q15043
NSVSAFFHNLDIDFK

DSEL

596

Q8IZU8
SNVHFTGEKELEFRS

CASP2

206

P42575
SFNFDRVFHGNETTK

CENPE

46

Q02224
NFAGNRFSDHVALLS

DHX9

906

Q08211
HDFGSSTSKFTLNEQ

LIFR

116

P42702
EEKDNHTGFHTLNFT

OTOGL

2146

Q3ZCN5
AVFDQHRRKFDNFSS

NUP210L

801

Q5VU65
GENAKIHFSFSNLVS

PCDH11Y

311

Q9BZA8
RDSLSHDFNGLNLSK

UPF2

186

Q9HAU5
ANSRQEFEHLKGDFG

LAMA4

1476

Q16363
SEFQRSFKHDVRGNA

HSPA14

241

Q0VDF9
DNLIEFLQKSHSGFQ

ORC3

71

Q9UBD5
FLQKSHSGFQKNSRD

ORC3

76

Q9UBD5
AAGHQFESSFELRKV

MAP3K5

441

Q99683
QRAQDGDFIFSKEHT

PTGFRN

481

Q9P2B2
AEDSFKTHNLSINGN

RTKN2

246

Q8IZC4
KTHNLSINGNEESSF

RTKN2

251

Q8IZC4
DKSQFHRQTVEFLGF

RTL1

766

A6NKG5
RDPGFFSNKHDTVSQ

RTTN

271

Q86VV8
TGETFTFKRHSQDAS

AK9

541

Q5TCS8
GSEAQDSNRFASHLK

SPEF2

1731

Q9C093
LGRQISHFFSENEDF

TRIM32

561

Q13049
TTVQEDAHFKAFFQS

RNF38

41

Q9H0F5
FVASKNEQESRHAAS

REPS1

101

Q96D71
RLSKFTRQGDFESDH

SMCHD1

201

A6NHR9
RNFLLNGSSQKTFHS

TMEM132B

981

Q14DG7
SFEHDEFLSNNLKRG

TMEM200A

471

Q86VY9
AFVKTENSHAAQSAR

LRRN3

556

Q9H3W5
SKVQEARKSFFSGHA

PLPP3

186

O14495
TLAELGFQDSKFHQA

PTAFR

256

P25105
FFATSQNNRGEHLVD

RASGRF2

701

O14827
AQHVFRSFDSNLDGT

RCVRN

66

P35243
DINKVFEFGHTNRTT

KIFC3

621

Q9BVG8
DFFFIDVSSNLRKNH

PKDREJ

1356

Q9NTG1
NANDGKFDHPDRTFS

NBEA

2401

Q8NFP9
QHFRNDIIFSKAGDE

PTCHD4

586

Q6ZW05
SQSFHLASNKNRDIF

HOATZ

81

Q6PI97
RALSFFHQKGLQDFD

SEMA4A

51

Q9H3S1
GFFFDNNSHDRVKIK

SETD3

326

Q86TU7
TSNGHLSENEARKKF

SIK1B

116

A0A0B4J2F2
TSNGHLSENEARKKF

SIK1

116

P57059
SGNDFEETKAHIRFS

SHROOM3

821

Q8TF72
QSQDGFEHKEFFSSQ

ST6GAL2

101

Q96JF0
FEHKEFFSSQVGRKS

ST6GAL2

106

Q96JF0
AFNHIELNSDQSGKS

SLC5A8

591

Q8N695
TGRTAENTFNKTHTF

NSMCE4A

201

Q9NXX6
FFENRKGLSSHARSH

WIZ

1051

O95785
NDSFAGKGHTNQVSR

WDR1

356

O75083
FTESQLQSHFGEKNG

POLH

281

Q9Y253
TRFHNQSELKDFGTE

SOST

171

Q9BQB4
AGAALAQDAFHRKAS

SH3RF1

786

Q7Z6J0
AQDAFHRKASSLDSA

SH3RF1

791

Q7Z6J0
FSDHNFAGSNKIAEI

TSPY10

261

P0CW01
AFRESNKEGAHSSTF

TMTC4

191

Q5T4D3
SQALASGFHRGKQED

USP17L3

146

A6NCW0
FSDHNFAGSNKIAEI

TSPY2

261

A6NKD2
NFHFSNESTAVKERD

GTF2H1

76

P32780
ANHDELISKSFQGSQ

YPEL1

31

O60688
SFHDNDIFSGQVNKF

TTLL11

261

Q8NHH1
KEFLSTAQGNREVFH

ZNF761

56

Q86XN6
CGKAFFDRSSLTQHQ

ZNF2

346

Q9BSG1
SNANHRTGVSFTFSK

ZNF804B

211

A4D1E1
GKSFSDGSNFSRHQT

ZSCAN2

256

Q7Z7L9
KTFSRRSNLVEHGQF

ZNF573

281

Q86YE8
FSDHNFAGSNKIAEI

TSPY1

261

Q01534
QHAFRTFDKNGDGTI

VSNL1

66

P62760
HSQSDFFTAKLSRSE

UNC13C

536

Q8NB66
TLGKNSFNFSDLNHS

REV3L

701

O60673
TLKEFRGHSSFVNEA

SMU1

341

Q2TAY7
NTSSKFRHLLSNDGY

THAP9

886

Q9H5L6
NLSEELSHSAFGQAF

TTI2

16

Q6NXR4
NHTANEFARKQVTGF

SNX18

446

Q96RF0
KGSYNDFSFVTHTNR

PISD

346

Q9UG56
FVNLHSFQVRDDSSG

VAV1

446

P15498
FDERAANFENHSGKL

VCL

626

P18206
GKAFSQSANLTVHER

ZNF660

56

Q6AZW8
GKAFSSSSVFLQHQR

ZNF620

286

Q6ZNG0
GFEAEFNKSQTSFHL

TRAV8-6

81

A0A0B4J262
QREKHAEFQGRSTEF

ZDBF2

981

Q9HCK1
SDNTVSKRGFRAHFF

TLL2

716

Q9Y6L7
IHNFLKQTGTFSNDS

TEX11

721

Q8IYF3
FKRREADQTHAQNFS

TMEM201

191

Q5SNT2
HSQSFLATGSNLRKD

SEPTIN10

431

Q9P0V9
GFEAEFNKSQTSFHL

TRAV3

81

A0A0B4J244
IFDNTNSQGHKFFRK

SAXO2

376

Q658L1
FSDHNFAGSNKIAEI

TSPY3

261

P0CV98
FSDHNFAGSNKIAEI

TSPY8

261

P0CW00
ANHDELISKSFQGSQ

YPEL2

31

Q96QA6
SKSQFLLGQNHDIFD

ZNF350

116

Q9GZX5
AHFSGDVSKASALQD

XPOT

466

O43592
LNHAVGFASRTSKAF

XPOT

651

O43592
GKAFSQNSSLVQHER

ZNF8

291

P17098
CGKAFTDRSNLFTHQ

ZNF484

641

Q5JVG2
KEFSSTAQGNREVFH

ZNF765

56

Q7L2R6
FSLGFGQEDHKDTSR

TESPA1

166

A2RU30
TQAGHQDKDTTFDLF

THBS2

16

P35442
DFRTSAKISNQIFHE

WDR25

411

Q64LD2
DCGKAFSQSSNLFRH

ZNF396

311

Q96N95
FQFGDARKDSSLHIT

TRAV27

81

A0A087WT01
KAFSDGSALTQHQRI

ZNF329

266

Q86UD4
NEHFSNVFGFLSQKA

VPS33B

291

Q9H267
GKAFSNRADLIRHFS

ZNF805

461

Q5CZA5
QGFHDEAAFFTNKRS

ZNF248

221

Q8NDW4
GKAFTDRSNFNKHQT

ZNF81

616

P51508
DVFAAQNHRSSKFSS

ZBTB40

1031

Q9NUA8
FFKHNGSLFQETAAS

TTLL13

491

A6NNM8
DGTLQSFSTVHEKFN

WDR36

401

Q8NI36
ANHDDLISKSFQGSQ

YPEL3

31

P61236
CGKAFSDRSSLNQHE

ZNF554

441

Q86TJ5
GKAFSSSSSFRNHER

ZNF266

526

Q14584
RFDGTHSNFILANAQ

KCNH8

21

Q96L42
QTGFSDIKSHAFFRS

PRKCZ

506

Q05513
NNSSRFGKFVEIHFN

MYO6

201

Q9UM54
GARFSFKESHNSASN

MYBPC2

101

Q14324