Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neurotrophin receptor activity	NTRK2 NTRK3	1.27e-05	5	23	2	GO:0005030
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	NTRK2 NTRK3 IGF1R	5.57e-05	65	23	3	GO:0004714
GeneOntologyMolecularFunction	neurotrophin binding	NTRK2 NTRK3	8.32e-05	12	23	2	GO:0043121
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	NTRK2 NTRK3 IGF1R	1.24e-04	85	23	3	GO:0019199
GeneOntologyMolecularFunction	protein tyrosine kinase activity	NTRK2 NTRK3 IGF1R	5.97e-04	145	23	3	GO:0004713
GeneOntologyMolecularFunction	growth factor binding	NTRK2 NTRK3 IGF1R	7.39e-04	156	23	3	GO:0019838
GeneOntologyMolecularFunction	p53 binding	USP7 NTRK3	3.52e-03	77	23	2	GO:0002039
GeneOntologyBiologicalProcess	peripheral nervous system axon ensheathment	DICER1 NTRK2 NTRK3	5.63e-06	33	22	3	GO:0032292
GeneOntologyBiologicalProcess	myelination in peripheral nervous system	DICER1 NTRK2 NTRK3	5.63e-06	33	22	3	GO:0022011
GeneOntologyBiologicalProcess	Schwann cell development	DICER1 NTRK2 NTRK3	1.66e-05	47	22	3	GO:0014044
GeneOntologyBiologicalProcess	Schwann cell differentiation	DICER1 NTRK2 NTRK3	2.67e-05	55	22	3	GO:0014037
GeneOntologyBiologicalProcess	neuronal action potential propagation	NTRK2 NTRK3	7.12e-05	12	22	2	GO:0019227
GeneOntologyBiologicalProcess	action potential propagation	NTRK2 NTRK3	7.12e-05	12	22	2	GO:0098870
GeneOntologyBiologicalProcess	pallium development	DICER1 VPS13B NTRK2 IGF1R	8.21e-05	222	22	4	GO:0021543
GeneOntologyBiologicalProcess	positive regulation of axon regeneration	NTRK3 IGF1R	1.46e-04	17	22	2	GO:0048680
GeneOntologyBiologicalProcess	peripheral nervous system development	DICER1 NTRK2 NTRK3	1.50e-04	98	22	3	GO:0007422
GeneOntologyBiologicalProcess	positive regulation of neuron projection regeneration	NTRK3 IGF1R	1.64e-04	18	22	2	GO:0070572
GeneOntologyBiologicalProcess	mechanoreceptor differentiation	DICER1 NTRK2 NTRK3	1.79e-04	104	22	3	GO:0042490
GeneOntologyBiologicalProcess	telencephalon development	DICER1 VPS13B NTRK2 IGF1R	3.83e-04	332	22	4	GO:0021537
GeneOntologyCellularComponent	microbody lumen	ACOT8 MLYCD	1.66e-03	55	23	2	GO:0031907
GeneOntologyCellularComponent	peroxisomal matrix	ACOT8 MLYCD	1.66e-03	55	23	2	GO:0005782
GeneOntologyCellularComponent	glutamatergic synapse	DICER1 NTRK2 NTRK3 IGF1R ARHGAP39	1.69e-03	817	23	5	GO:0098978
GeneOntologyCellularComponent	growth cone	KATNA1 DICER1 NTRK2	2.37e-03	245	23	3	GO:0030426
GeneOntologyCellularComponent	axon	KATNA1 DICER1 NTRK2 NTRK3 IGF1R	2.47e-03	891	23	5	GO:0030424
GeneOntologyCellularComponent	site of polarized growth	KATNA1 DICER1 NTRK2	2.59e-03	253	23	3	GO:0030427
MousePheno	decreased sensory neuron number	KCNV2 NTRK2 NTRK3 IGF1R	4.38e-05	181	16	4	MP:0000966
MousePheno	small nodose ganglion	NTRK2 NTRK3	5.50e-05	10	16	2	MP:0001088
MousePheno	small petrosal ganglion	NTRK2 NTRK3	5.50e-05	10	16	2	MP:0001085
MousePheno	small vestibular ganglion	NTRK2 NTRK3	6.71e-05	11	16	2	MP:0003987
MousePheno	abnormal nodose ganglion morphology	NTRK2 NTRK3	9.51e-05	13	16	2	MP:0001087
MousePheno	abnormal petrosal ganglion morphology	NTRK2 NTRK3	1.11e-04	14	16	2	MP:0001084
MousePheno	abnormal neuron number	KATNA1 KCNV2 NTRK2 NTRK3 IGF1R	1.17e-04	456	16	5	MP:0008946
MousePheno	abnormal lumbar dorsal root ganglion morphology	NTRK2 NTRK3	1.28e-04	15	16	2	MP:0006404
MousePheno	small cochlear ganglion	NTRK2 NTRK3	1.65e-04	17	16	2	MP:0003986
MousePheno	small trigeminal ganglion	NTRK2 NTRK3	2.31e-04	20	16	2	MP:0001093
MousePheno	abnormal cochlear sensory neuron innervation pattern	NTRK2 NTRK3	2.80e-04	22	16	2	MP:0014489
MousePheno	abnormal vestibulocochlear nerve morphology	NTRK2 NTRK3	3.06e-04	23	16	2	MP:0001072
MousePheno	abnormal vestibular ganglion morphology	NTRK2 NTRK3	3.34e-04	24	16	2	MP:0002856
MousePheno	abnormal glossopharyngeal ganglion morphology	NTRK2 NTRK3	5.97e-04	32	16	2	MP:0001096
MousePheno	decreased neuron number	KCNV2 NTRK2 NTRK3 IGF1R	7.25e-04	376	16	4	MP:0008948
MousePheno	abnormal vagus ganglion morphology	NTRK2 NTRK3	1.18e-03	45	16	2	MP:0001100
Domain	Tyr_kinase_rcpt_2_CS	NTRK2 NTRK3 IGF1R	2.01e-07	11	21	3	IPR002011
Domain	RECEPTOR_TYR_KIN_II	NTRK2 NTRK3 IGF1R	2.68e-07	12	21	3	PS00239
Domain	Tyr_kinase_NGF_rcpt	NTRK2 NTRK3	3.61e-06	3	21	2	IPR020777
Domain	NTRK_C2	NTRK2 NTRK3	3.61e-06	3	21	2	IPR031635
Domain	TPKR_C2	NTRK2 NTRK3	3.61e-06	3	21	2	PF16920
Domain	TyrKc	NTRK2 NTRK3 IGF1R	1.26e-04	88	21	3	SM00219
Domain	Tyr_kinase_cat_dom	NTRK2 NTRK3 IGF1R	1.26e-04	88	21	3	IPR020635
Domain	PROTEIN_KINASE_TYR	NTRK2 NTRK3 IGF1R	1.69e-04	97	21	3	PS00109
Domain	Tyr_kinase_AS	NTRK2 NTRK3 IGF1R	1.69e-04	97	21	3	IPR008266
Domain	DSRM	DICER1 NKRF	2.04e-04	19	21	2	SM00358
Domain	dsrm	DICER1 NKRF	2.26e-04	20	21	2	PF00035
Domain	Pkinase_Tyr	NTRK2 NTRK3 IGF1R	3.91e-04	129	21	3	PF07714
Domain	-	DICER1 NKRF	4.16e-04	27	21	2	3.30.160.20
Domain	dsRBD_dom	DICER1 NKRF	4.47e-04	28	21	2	IPR014720
Domain	Ser-Thr/Tyr_kinase_cat_dom	NTRK2 NTRK3 IGF1R	4.76e-04	138	21	3	IPR001245
Domain	-	IL1RL2 COL14A1 NTRK2 NTRK3 IGF1R	7.04e-04	663	21	5	2.60.40.10
Domain	Ig-like_fold	IL1RL2 COL14A1 NTRK2 NTRK3 IGF1R	9.35e-04	706	21	5	IPR013783
Domain	WW	ARHGAP39 PCIF1	1.26e-03	47	21	2	PF00397
Domain	WW	ARHGAP39 PCIF1	1.32e-03	48	21	2	SM00456
Domain	WW_DOMAIN_2	ARHGAP39 PCIF1	1.49e-03	51	21	2	PS50020
Domain	WW_DOMAIN_1	ARHGAP39 PCIF1	1.49e-03	51	21	2	PS01159
Domain	WW_dom	ARHGAP39 PCIF1	1.54e-03	52	21	2	IPR001202
Domain	LRRNT	NTRK2 NTRK3	1.60e-03	53	21	2	PF01462
Domain	Cys-rich_flank_reg_C	NTRK2 NTRK3	4.54e-03	90	21	2	IPR000483
Domain	LRRCT	NTRK2 NTRK3	4.54e-03	90	21	2	SM00082
Domain	LRRNT	NTRK2 NTRK3	5.36e-03	98	21	2	IPR000372
Domain	LRRNT	NTRK2 NTRK3	5.36e-03	98	21	2	SM00013
Domain	L_dom-like	NTRK2 NTRK3 IGF1R	5.65e-03	328	21	3	IPR032675
Domain	Protein_kinase_ATP_BS	NTRK2 NTRK3 IGF1R	8.41e-03	379	21	3	IPR017441
Domain	IG	IL1RL2 NTRK2 NTRK3	1.12e-02	421	21	3	SM00409
Domain	Ig_sub	IL1RL2 NTRK2 NTRK3	1.12e-02	421	21	3	IPR003599
Pathway	PID_SHP2_PATHWAY	NTRK2 NTRK3 IGF1R	4.09e-05	57	17	3	M100
Pathway	REACTOME_BETA_OXIDATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS	ACOT8 MLYCD	7.48e-05	11	17	2	M27298
Pathway	REACTOME_BETA_OXIDATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS	ACOT8 MLYCD	7.48e-05	11	17	2	MM15002
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_UBIQUITINATION_OF_RTK_BY_CBL	NTRK2 IGF1R	4.04e-04	25	17	2	M47934
Pathway	REACTOME_PEROXISOMAL_LIPID_METABOLISM	ACOT8 MLYCD	5.08e-04	28	17	2	MM15010
Pathway	REACTOME_PEROXISOMAL_LIPID_METABOLISM	ACOT8 MLYCD	5.45e-04	29	17	2	M2286
Pubmed	Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.	NTRK2 NTRK3 IGF1R	2.12e-08	9	23	3	8530078
Pubmed	trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues.	NTRK2 NTRK3 IGF1R	4.15e-08	11	23	3	8223273
Pubmed	A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing.	NTRK2 NTRK3 IGF1R	9.15e-08	14	23	3	8114702
Pubmed	Severe sensory deficits but normal CNS development in newborn mice lacking TrkB and TrkC tyrosine protein kinase receptors.	NTRK2 NTRK3	4.18e-07	2	23	2	9421165
Pubmed	Abnormal development of pacinian corpuscles in double trkB;trkC knockout mice.	NTRK2 NTRK3	4.18e-07	2	23	2	17101216
Pubmed	The combined effects of trkB and trkC mutations on the innervation of the inner ear.	NTRK2 NTRK3	4.18e-07	2	23	2	9881298
Pubmed	Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.	NTRK2 NTRK3	4.18e-07	2	23	2	32315394
Pubmed	Conditional deletion of TrkC does not modify limbic epileptogenesis.	NTRK2 NTRK3	4.18e-07	2	23	2	22980123
Pubmed	Mapping of the tyrosine kinase receptors trkA (NTRK1), trkB (NTRK2) and trkC(NTRK3) to human chromosomes 1q22, 9q22 and 15q25 by fluorescence in situ hybridization.	NTRK2 NTRK3	4.18e-07	2	23	2	9195161
Pubmed	TrkB but not trkC receptors are necessary for postnatal maintenance of hippocampal spines.	NTRK2 NTRK3	4.18e-07	2	23	2	17442456
Pubmed	Lack of TrkB and TrkC signaling alters the synaptogenesis and maturation of mossy fiber terminals in the hippocampus.	NTRK2 NTRK3	4.18e-07	2	23	2	15726425
Pubmed	Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.	NTRK2 NTRK3	4.18e-07	2	23	2	11877382
Pubmed	Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung.	NTRK2 NTRK3	4.18e-07	2	23	2	18293376
Pubmed	Selective activation and down-regulation of Trk receptors by neurotrophins in human neurons co-expressing TrkB and TrkC.	NTRK2 NTRK3	4.18e-07	2	23	2	35536742
Pubmed	The TrkB-positive dopaminergic neurons are less sensitive to MPTP insult in the substantia nigra of adult C57/BL mice.	NTRK2 NTRK3	4.18e-07	2	23	2	21562748
Pubmed	Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets.	NTRK2 NTRK3	4.18e-07	2	23	2	7588071
Pubmed	USP7 reduces the level of nuclear DICER, impairing DNA damage response and promoting cancer progression.	USP7 DICER1	4.18e-07	2	23	2	37867415
Pubmed	Haploinsufficiency in trkB and/or trkC neurotrophin receptors causes structural alterations in the aged hippocampus and amygdala.	NTRK2 NTRK3	4.18e-07	2	23	2	14622193
Pubmed	Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma.	NTRK2 NTRK3	4.18e-07	2	23	2	23332094
Pubmed	Wnt1-cre-mediated conditional loss of Dicer results in malformation of the midbrain and cerebellum and failure of neural crest and dopaminergic differentiation in mice.	DICER1 NTRK2 NTRK3	1.12e-06	31	23	3	20457670
Pubmed	Dok5 is substrate of TrkB and TrkC receptors and involved in neurotrophin induced MAPK activation.	NTRK2 NTRK3	1.25e-06	3	23	2	16647839
Pubmed	Gene expression of TRK neurotrophin receptors in advanced neuroblastomas in Singapore--a pilot study.	NTRK2 NTRK3	1.25e-06	3	23	2	21728718
Pubmed	Neurotrophin actions during the development of the peripheral nervous system.	NTRK2 NTRK3	1.25e-06	3	23	2	10383116
Pubmed	Pan-Trk Immunohistochemistry Is an Efficient and Reliable Screen for the Detection of NTRK Fusions.	NTRK2 NTRK3	1.25e-06	3	23	2	28719467
Pubmed	TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice.	NTRK2 NTRK3	1.25e-06	3	23	2	20553714
Pubmed	Survival of inner ear sensory neurons in trk mutant mice.	NTRK2 NTRK3	1.25e-06	3	23	2	9232598
Pubmed	Developmental dependency of Merkel endings on trks in the palate.	NTRK2 NTRK3	1.25e-06	3	23	2	11295244
Pubmed	DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma.	NTRK2 NTRK3	1.25e-06	3	23	2	21295543
Pubmed	Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours.	NTRK2 NTRK3	1.25e-06	3	23	2	21552290
Pubmed	TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons.	NTRK2 NTRK3	1.25e-06	3	23	2	8918886
Pubmed	Gangliosides activate Trk receptors by inducing the release of neurotrophins.	NTRK2 NTRK3	1.25e-06	3	23	2	12388556
Pubmed	Trk receptor expression and inhibition in neuroblastomas.	NTRK2 NTRK3	1.25e-06	3	23	2	19417027
Pubmed	Dimerization of the Trk receptors in the plasma membrane: effects of their cognate ligands.	NTRK2 NTRK3	1.25e-06	3	23	2	30366959
Pubmed	Prognostic value of tropomyosin-related kinases A, B, and C in gastric cancer.	NTRK2 NTRK3	1.25e-06	3	23	2	26459250
Pubmed	A chemical-genetic approach to studying neurotrophin signaling.	NTRK2 NTRK3	1.25e-06	3	23	2	15820690
Pubmed	The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.	NTRK2 NTRK3	1.25e-06	3	23	2	16862449
Pubmed	NeuroD regulates neuronal migration.	NTRK2 NTRK3	1.25e-06	3	23	2	23652629
Pubmed	Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins.	NTRK2 NTRK3	1.25e-06	3	23	2	7823156
Pubmed	Crystal Structures of Neurotrophin Receptors Kinase Domain.	NTRK2 NTRK3	1.25e-06	3	23	2	28215291
Pubmed	TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations.	NTRK2 NTRK3	1.25e-06	3	23	2	31871300
Pubmed	The Effects of IGF-1 on Trk Expressing DRG Neurons with HIV-gp120- Induced Neurotoxicity.	NTRK2 NTRK3	1.25e-06	3	23	2	26652865
Pubmed	Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons.	NTRK2 NTRK3	1.25e-06	3	23	2	8575307
Pubmed	ESMO recommendations on the standard methods to detect NTRK fusions in daily practice and clinical research.	NTRK2 NTRK3	1.25e-06	3	23	2	31268127
Pubmed	Developmental dependency of Meissner corpuscles on trkB but not trkA or trkC.	NTRK2 NTRK3	1.25e-06	3	23	2	10674466
Pubmed	NTRK fusion analysis reveals enrichment in Middle Eastern BRAF wild-type PTC.	NTRK2 NTRK3	1.25e-06	3	23	2	33524004
Pubmed	The trk family of tyrosine protein kinase receptors.	NTRK2 NTRK3	1.25e-06	3	23	2	1751544
Pubmed	Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, trkA, trkB, and trkC) in the adult human peripheral nervous system and nonneural tissues.	NTRK2 NTRK3	1.25e-06	3	23	2	8895847
Pubmed	The development of myelinated nociceptors is dependent upon trks in the trigeminal ganglion.	NTRK2 NTRK3	1.25e-06	3	23	2	15530548
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	NTRK2 NTRK3 IGF1R	2.46e-06	40	23	3	30898150
Pubmed	N-acetylserotonin activates TrkB receptor in a circadian rhythm.	NTRK2 NTRK3	2.51e-06	4	23	2	20133677
Pubmed	An autocrine function of nerve growth factor for cell cycle regulation of vascular endothelial cells.	NTRK2 NTRK3	2.51e-06	4	23	2	14706643
Pubmed	Ubiquitin Regulation of Trk Receptor Trafficking and Degradation.	NTRK2 NTRK3	2.51e-06	4	23	2	29911254
Pubmed	The dependence receptor TrkC regulates the number of sensory neurons during DRG development.	NTRK2 NTRK3	2.51e-06	4	23	2	30071216
Pubmed	Neurotrophin receptors: a window into neuronal differentiation.	NTRK2 NTRK3	2.51e-06	4	23	2	1327010
Pubmed	Candidate genes for panic disorder: insight from human and mouse genetic studies.	NTRK2 NTRK3	2.51e-06	4	23	2	17543035
Pubmed	Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR.	NTRK2 NTRK3	2.51e-06	4	23	2	9927421
Pubmed	Differential expression of neurotrophin receptors during renal development.	NTRK2 NTRK3	2.51e-06	4	23	2	8306895
Pubmed	Dependence receptors: the trophic theory revisited.	NTRK3 IGF1R	2.51e-06	4	23	2	21139137
Pubmed	Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons.	NTRK2 NTRK3	2.51e-06	4	23	2	7991545
Pubmed	Association of the atypical protein kinase C-interacting protein p62/ZIP with nerve growth factor receptor TrkA regulates receptor trafficking and Erk5 signaling.	NTRK2 NTRK3	2.51e-06	4	23	2	12471037
Pubmed	Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not.	NTRK2 NTRK3	2.51e-06	4	23	2	20811452
Pubmed	p75 and TrkC neurotrophin receptors demonstrate a different immunoreactivity profile in comparison to TrkA and TrkB receptors in human normal pituitary gland and adenomas.	NTRK2 NTRK3	2.51e-06	4	23	2	18319596
Pubmed	Expression of PTPRO during mouse development suggests involvement in axonogenesis and differentiation of NT-3 and NGF-dependent neurons.	NTRK2 NTRK3	2.51e-06	4	23	2	12532410
Pubmed	Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra.	NTRK2 NTRK3	2.51e-06	4	23	2	16037097
Pubmed	Neurotrophin receptors expression and JNK pathway activation in human astrocytomas.	NTRK2 NTRK3	2.51e-06	4	23	2	17971243
Pubmed	Binding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkC.	NTRK2 NTRK3	2.51e-06	4	23	2	8621424
Pubmed	[The Role of Neurotrophins and Neurexins Genes in the Risk of Paranoid Schizophrenia in Russians and Tatars].	NTRK2 NTRK3	2.51e-06	4	23	2	26410934
Pubmed	Increased expression of neurotrophins and their receptors in the mechanically compressed spinal cord of the spinal hyperostotic mouse (twy/twy).	NTRK2 NTRK3	2.51e-06	4	23	2	12774239
Pubmed	Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression.	NTRK2 NTRK3	2.51e-06	4	23	2	11487640
Pubmed	The transcription factor Runx3 represses the neurotrophin receptor TrkB during lineage commitment of dorsal root ganglion neurons.	NTRK2 NTRK3	2.51e-06	4	23	2	17584746
Pubmed	TrkA, but not TrkC, receptors are essential for survival of sympathetic neurons in vivo.	NTRK2 NTRK3	2.51e-06	4	23	2	8815902
Pubmed	A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching.	NTRK2 NTRK3	2.51e-06	4	23	2	23598414
Pubmed	A tripartite complex composed of ETV6-NTRK3, IRS1 and IGF1R is required for ETV6-NTRK3-mediated membrane localization and transformation.	NTRK3 IGF1R	2.51e-06	4	23	2	21804605
Pubmed	Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription.	NTRK2 NTRK3	2.51e-06	4	23	2	17254333
Pubmed	A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.	NTRK2 NTRK3	4.18e-06	5	23	2	15167895
Pubmed	Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.	NTRK2 NTRK3	4.18e-06	5	23	2	15513915
Pubmed	Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC.	NTRK2 NTRK3	4.18e-06	5	23	2	10207144
Pubmed	The role of neurotrophin receptors in female germ-cell survival in mouse and human.	NTRK2 NTRK3	4.18e-06	5	23	2	14507777
Pubmed	Neurotrophic factor-related gene polymorphisms and adult attention deficit hyperactivity disorder (ADHD) score in a high-risk male population.	NTRK2 NTRK3	4.18e-06	5	23	2	18428117
Pubmed	Expression of neurotrophin receptors by retinoinvasive uveal melanoma.	NTRK2 NTRK3	4.18e-06	5	23	2	22343487
Pubmed	Timing of neuronal death in trkA, trkB and trkC mutant embryos reveals developmental changes in sensory neuron dependence on Trk signalling.	NTRK2 NTRK3	4.18e-06	5	23	2	8898237
Pubmed	Characterization of sensory neuronal subtypes innervating mouse tongue.	NTRK2 NTRK3	4.18e-06	5	23	2	30408082
Pubmed	Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.	NTRK2 NTRK3	4.18e-06	5	23	2	21102451
Pubmed	The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice.	NTRK2 NTRK3	4.18e-06	5	23	2	36418415
Pubmed	Dynamic expression pattern of leucine-rich repeat neuronal protein 4 in the mouse dorsal root ganglia during development.	NTRK2 NTRK3	4.18e-06	5	23	2	23701859
Pubmed	Formation of a full complement of cranial proprioceptors requires multiple neurotrophins.	NTRK2 NTRK3	4.18e-06	5	23	2	10842362
Pubmed	The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death.	NTRK2 NTRK3	4.18e-06	5	23	2	9472042
Pubmed	Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking.	NTRK2 NTRK3	6.26e-06	6	23	2	26687362
Pubmed	Genetic evidence for selective neurotrophin 3 signalling through TrkC but not TrkB in vivo.	NTRK2 NTRK3	6.26e-06	6	23	2	16142215
Pubmed	Neural crest boundary cap cells constitute a source of neuronal and glial cells of the PNS.	NTRK2 NTRK3	6.26e-06	6	23	2	15322547
Pubmed	Absence of sensory neurons before target innervation in brain-derived neurotrophic factor-, neurotrophin 3-, and TrkC-deficient embryonic mice.	NTRK2 NTRK3	6.26e-06	6	23	2	9364058
Pubmed	Receptor tyrosine kinases fall into distinct classes based on their inferred signaling networks.	NTRK2 IGF1R	6.26e-06	6	23	2	23861540
Pubmed	Neurotrophins and neurotransmitters in human palatine tonsils: an immunohistochemical and RT-PCR analysis.	NTRK2 NTRK3	6.26e-06	6	23	2	16786155
Pubmed	Characterization of neurotrophin and Trk receptor functions in developing sensory ganglia: direct NT-3 activation of TrkB neurons in vivo.	NTRK2 NTRK3	6.26e-06	6	23	2	9728914
Pubmed	Neurotrophins are not required for normal embryonic development of olfactory neurons.	NTRK2 NTRK3	6.26e-06	6	23	2	11356021
Pubmed	ShcB and ShcC activation by the Trk family of receptor tyrosine kinases.	NTRK2 NTRK3	6.26e-06	6	23	2	12006576
Pubmed	Control of patterns of corneal innervation by Pax6.	NTRK2 NTRK3	6.26e-06	6	23	2	19029029
Pubmed	Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.	NTRK2 NTRK3	6.26e-06	6	23	2	22048155
Pubmed	Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis.	NTRK2 NTRK3	6.26e-06	6	23	2	23869086
Pubmed	NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development.	NTRK2 NTRK3	6.26e-06	6	23	2	11152640
Interaction	DOK5 interactions	NTRK2 NTRK3 IGF1R	1.48e-06	21	22	3	int:DOK5
Interaction	KLHL23 interactions	USP7 KLHL11 ACOT8	1.45e-05	44	22	3	int:KLHL23
Interaction	NHSL2 interactions	USP7 COL14A1 SORBS3	2.86e-05	55	22	3	int:NHSL2
Interaction	KATNA1 interactions	KATNA1 ARHGAP39 SORBS3	5.40e-05	68	22	3	int:KATNA1
Cytoband	20q13.12	ACOT8 PCIF1	4.18e-04	60	23	2	20q13.12
Cytoband	19q13.33	GPR32 TMEM143	1.29e-03	106	23	2	19q13.33
Cytoband	16p13.3	USP7 ERVK13-1	6.61e-03	244	23	2	16p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	COL14A1 ARHGAP39	1.36e-02	355	23	2	chr8q24
Cytoband	Ensembl 112 genes in cytogenetic band chr20q13	ACOT8 PCIF1	1.88e-02	422	23	2	chr20q13
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	USP7 ERVK13-1	1.91e-02	426	23	2	chr16p13
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	NTRK2 NTRK3 IGF1R	5.51e-06	40	16	3	321
GeneFamily	Fibronectin type III domain containing	COL14A1 IGF1R	8.61e-03	160	16	2	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NTRK2 NTRK3	8.71e-03	161	16	2	593
Coexpression	GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_UP	DICER1 NKRF IGF1R ARHGAP39	2.60e-05	200	23	4	M6352
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-Tregs\|GI_small-bowel / Manually curated celltypes from each tissue	IL1RL2 NTRK2 NTRK3	7.01e-05	157	23	3	c44bd530e396b08f16f284e185dcb830843959ea
ToppCell	21-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	COL14A1 NTRK2 NTRK3	7.28e-05	159	23	3	4f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL11 NTRK3 ANKRD53	7.98e-05	164	23	3	43630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL11 NTRK3 ANKRD53	7.98e-05	164	23	3	46208f18325976c89f572f6627aea0582142b92d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KLHL11 NTRK3 ANKRD53	7.98e-05	164	23	3	108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	COL14A1 NTRK2 NTRK3	9.03e-05	171	23	3	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	COL14A1 NTRK3 SORBS3	9.19e-05	172	23	3	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 NTRK3 SORBS3	9.67e-05	175	23	3	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 NTRK3 SORBS3	9.67e-05	175	23	3	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	Pericytes-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	COL14A1 NTRK2 NTRK3	1.02e-04	178	23	3	a2448d868da2abe48c394c51264aad03e866dfec
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	COL14A1 NTRK2 NTRK3	1.03e-04	179	23	3	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	COL14A1 NTRK2 NTRK3	1.05e-04	180	23	3	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL14A1 NTRK2 NTRK3	1.09e-04	182	23	3	97bb07478f56a937b490fba121ee603db64134a1
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL14A1 NTRK2 NTRK3	1.09e-04	182	23	3	1c1a687f728341c209b048b6715bcddd0ac20069
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	COL14A1 NTRK2 NTRK3	1.09e-04	182	23	3	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL14A1 NTRK3 SORBS3	1.10e-04	183	23	3	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	Pericytes-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	COL14A1 NTRK2 NTRK3	1.12e-04	184	23	3	cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL14A1 NTRK2 NTRK3	1.14e-04	185	23	3	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL14A1 NTRK2 NTRK3	1.16e-04	186	23	3	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-VSMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL14A1 NTRK2 NTRK3	1.16e-04	186	23	3	c7885fd6dc7dc8fffc96f0112c51a365cf8a8f80
ToppCell	IPF-Stromal-SMC\|World / Disease state, Lineage and Cell class	COL14A1 NTRK2 NTRK3	1.20e-04	188	23	3	b66264e8f8d536ed2beec31e6746c687718f239b
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	COL14A1 NTRK2 NTRK3	1.20e-04	188	23	3	409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCell	IPF-Stromal-SMC\|IPF / Disease state, Lineage and Cell class	COL14A1 NTRK2 NTRK3	1.20e-04	188	23	3	e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCell	Pericytes-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	COL14A1 NTRK2 NTRK3	1.20e-04	188	23	3	14c1c88a944c66f2eaac1ce7526815dcce1f5147
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL14A1 NTRK2 NTRK3	1.23e-04	190	23	3	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	5'-Adult-LymphNode-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD18 VPS53 IGF1R	1.25e-04	191	23	3	e5c41c3054ead03597c136eaccaf9822e6bb9d1a
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL14A1 NTRK2 NTRK3	1.25e-04	191	23	3	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL14A1 NTRK2 NTRK3	1.25e-04	191	23	3	053b3664f509baa107feaf90730f80ebf9ac8f14
ToppCell	5'-Adult-LymphNode-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD18 VPS53 IGF1R	1.25e-04	191	23	3	7e24175c7fabe5ea0b22b73173da4c3a666e5eb8
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL14A1 NTRK2 NTRK3	1.27e-04	192	23	3	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	COL14A1 NTRK2 NTRK3	1.27e-04	192	23	3	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	Pericytes\|World / lung cells shred on cell class, cell subclass, sample id	COL14A1 NTRK2 NTRK3	1.27e-04	192	23	3	057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL14A1 NTRK2 NTRK3	1.29e-04	193	23	3	9104b572d9c3c99080e4b7455993fbb944bf117d
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL14A1 NTRK2 NTRK3	1.31e-04	194	23	3	439d3f17c1f4736122b330e98add9292c7036a8e
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL14A1 NTRK2 NTRK3	1.33e-04	195	23	3	bbafea2262074beede78e286276a1927ecb80582
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL14A1 NTRK2 NTRK3	1.33e-04	195	23	3	145c50fa60d9df162152be0a6c070213ebdb8119
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	92c5be6e43571730c7709046856f6c8ae341a4a1
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	0e7ea6e66bfbb0006ee9651714fe48b0ee194290
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	54aefcebf13704f51de84379e2e22ec0734b9461
ToppCell	356C-Fibroblasts-Fibroblast-K_(Pericytes)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL14A1 NTRK2 NTRK3	1.35e-04	196	23	3	476812fc1422aca8010d771eff11fa6081f15a2d
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.37e-04	197	23	3	3f078be0b0f5e16edfb6d517beb20ac6178767f0
ToppCell	11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high\|Airway / Age, Tissue, Lineage and Cell class	COL14A1 NTRK2 NTRK3	1.37e-04	197	23	3	9a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.39e-04	198	23	3	dc6d9032c5029527e184ac13b887c0c1f22ef1c0
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.39e-04	198	23	3	bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Smooth_muscle-2\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	2c5ad62919c64ea0242e0984bb9932d2d975f4e3
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	b1753474152b82a0b811b9878c890a359e14919a
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	78b245d40c1e169ff2d26907b63d732e34529c5f
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCell	Parenchyma_COVID-19-Stromal-TX-Smooth_muscle-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	8e1e95c3a4b856415af208be6ad977e575bac189
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL14A1 NTRK2 NTRK3	1.41e-04	199	23	3	0a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_2-VSMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	fc802dd73f048881d9ddafd1b79ab3ca654510e2
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	cffddb39960cd611428397c1ec4023192e8af5a7
ToppCell	proximal-mesenchymal-Airway_Smooth_Muscle-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	6fa339666c4032b29ac521e88f0e917a57013cde
ToppCell	proximal-mesenchymal-Vascular_Smooth_Muscle-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	5c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCell	cellseq2-Mesenchymal-Myocytic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	e60aebd20be8012fa2febf6585ed34ebd64ec9b3
ToppCell	proximal-3-mesenchymal-Airway_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	e9a008bfe336002218c63d1c2231986e1b237621
ToppCell	proximal-mesenchymal-Vascular_Smooth_Muscle\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	22892afca3666e944102c231b3f10340d8391364
ToppCell	15-Airway\|15 / Age, Tissue, Lineage and Cell class	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCell	proximal-mesenchymal-Airway_Smooth_Muscle\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	5eeb8eb3fe74f5a8055c52ec77e38237bb63ed90
ToppCell	proximal-3-mesenchymal-Vascular_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL14A1 NTRK2 NTRK3	1.44e-04	200	23	3	870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCell	356C-Lymphocytic-ILC-ILC-3\|ILC / Donor, Lineage, Cell class and subclass (all cells)	USP7 KLHL11	4.49e-04	61	23	2	d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	MLYCD SORBS3	1.81e-03	123	23	2	511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL1RL2 COL14A1	2.14e-03	134	23	2	22c64b8c405f3752331b81c611d8e62bd58c07f7
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL1RL2 COL14A1	2.14e-03	134	23	2	9a9fa63b40d9bf94995d70ef19d2548cb418b138
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Proliferative_Immature_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	IL1RL2 NTRK3	2.17e-03	135	23	2	ed0f94d3839eea3b60217c4352159ed481361f13
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular\|TCGA-Stomach / Sample_Type by Project: Shred V9	NKRF ARHGAP39	2.27e-03	138	23	2	93497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_atypical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 ARHGAP39	2.60e-03	148	23	2	b7b5521162effc1024e7c399f690cd86d0b2f750
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACOT8 ARHGAP39	2.60e-03	148	23	2	6cd7ef4f29d9a0944f724d9d8117d4d25e517fe4
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NTRK2 ARHGAP39	2.74e-03	152	23	2	854c841c1fc6300b7e9be9c98cbf9b0ce2678690
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	NTRK3 SORBS3	2.95e-03	158	23	2	8d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL14A1 NTRK3	2.99e-03	159	23	2	a75ab494959575143cefdaec99e7aee3f318d559
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK2 NTRK3	2.99e-03	159	23	2	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	COVID-CD4-CD4_Treg\|COVID / Condition, Cell_class and T cell subcluster	KLHL11 TMEM143	2.99e-03	159	23	2	037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL14A1 NTRK3	2.99e-03	159	23	2	cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL14A1 NTRK3	2.99e-03	159	23	2	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	NTRK2 NTRK3	3.03e-03	160	23	2	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL14A1 NTRK3	3.03e-03	160	23	2	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	COL14A1 NTRK3	3.06e-03	161	23	2	64891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	COL14A1 NTRK3	3.06e-03	161	23	2	048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	NTRK2 NTRK3	3.06e-03	161	23	2	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	IL1RL2 COL14A1	3.18e-03	164	23	2	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DICER1 MLYCD	3.22e-03	165	23	2	436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DICER1 MLYCD	3.22e-03	165	23	2	242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	IL1RL2 NTRK3	3.22e-03	165	23	2	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 SORBS3	3.22e-03	165	23	2	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 SORBS3	3.22e-03	165	23	2	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	NTRK2 NTRK3	3.22e-03	165	23	2	ecaeb90a6bc27524ef6f2eefa72aec7315dbde3b
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	COL14A1 NTRK3	3.22e-03	165	23	2	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL14A1 NTRK2	3.22e-03	165	23	2	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD18 ARHGAP39	3.25e-03	166	23	2	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABHD18 ARHGAP39	3.25e-03	166	23	2	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL14A1 VPS13B	3.25e-03	166	23	2	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	Basal_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	IL1RL2 COL14A1	3.25e-03	166	23	2	aea2ae12e4746149ebc6da063ef694381c098f80
ToppCell	metastatic_Brain-Fibroblasts-Smooth_muscle_cells\|metastatic_Brain / Location, Cell class and cell subclass	COL14A1 NTRK3	3.25e-03	166	23	2	0da2c6ea1e62f1aafabafbbfbbcc6f7011739346
Drug	Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ABHD18 VPS53 IGF1R SORBS3	3.91e-05	193	23	4	2852_UP
Drug	Trifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A	VPS53 DICER1 SORBS3 PCIF1	4.07e-05	195	23	4	3559_DN
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	ABHD18 DICER1 COL14A1 IGF1R	4.23e-05	197	23	4	6867_UP
Drug	3-nitropropionic acid; Down 200; 10uM; PC3; HT_HG-U133A	ABHD18 VPS53 NTRK2 IGF1R	4.23e-05	197	23	4	6372_DN
Drug	Debrisoquin sulfate [581-88-4]; Up 200; 9uM; HL60; HG-U133A	NTRK3 MLYCD TMEM143 SORBS3	4.23e-05	197	23	4	1591_UP
Drug	Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A	ABHD18 NTRK2 MLYCD SORBS3	4.32e-05	198	23	4	4293_DN
Drug	Proglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A	USP7 VPS53 DICER1 NTRK2	4.40e-05	199	23	4	4337_UP
Drug	Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; PC3; HT_HG-U133A	COL14A1 NTRK2 NTRK3 IGF1R	4.49e-05	200	23	4	3779_UP
Drug	Androgen Antagonists	NTRK2 NTRK3 IGF1R	5.80e-05	75	23	3	ctd:D000726
Drug	CASs	DICER1 MLYCD	1.65e-04	19	23	2	CID000126806
Drug	lavendustin B	NTRK2 NTRK3	2.03e-04	21	23	2	CID000003895
Drug	enzacamene	NTRK2 NTRK3 IGF1R	2.90e-04	129	23	3	ctd:C038939
Drug	octylmethoxycinnamate	NTRK2 NTRK3 IGF1R	3.61e-04	139	23	3	ctd:C118580
Drug	butylparaben	NTRK2 NTRK3 IGF1R	5.15e-04	157	23	3	ctd:C038091
Drug	Vistar	DICER1 COL14A1	6.02e-04	36	23	2	CID000040896
Drug	n-propionyl-CoA	NKRF ACOT8 MLYCD	6.05e-04	166	23	3	CID000001033
Drug	Cephaeline dihydrochloride heptahydrate [6487-30-5]; Down 200; 6uM; HL60; HT_HG-U133A	USP7 DICER1 IGF1R	6.60e-04	171	23	3	2429_DN
Drug	LIGA20	NTRK2 NTRK3	7.07e-04	39	23	2	CID006441213
Drug	Anisomycin [22862-76-6]; Down 200; 15uM; HL60; HT_HG-U133A	ABHD18 DICER1 IGF1R	8.04e-04	183	23	3	1304_DN
Drug	imatinib	NTRK2 NTRK3 IGF1R SORBS3	8.36e-04	430	23	4	CID000005291
Drug	LY 294002; Up 200; 10uM; PC3; HT_HG-U133A	ABHD18 COL14A1 IGF1R	8.42e-04	186	23	3	4463_UP
Drug	CEP-701	NTRK2 NTRK3	8.60e-04	43	23	2	CID000126565
Drug	3-(2-carboxyindol-3-yl)propionic acid	NTRK2 NTRK3	8.60e-04	43	23	2	CID000169313
Drug	Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	USP7 ABHD18 MLYCD	8.69e-04	188	23	3	3770_DN
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	DICER1 NTRK2 IGF1R	9.09e-04	191	23	3	4279_DN
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Up 200; 16.4uM; MCF7; HT_HG-U133A	ABHD18 VPS53 SORBS3	9.09e-04	191	23	3	2824_UP
Drug	17-DMAG; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	VPS53 DICER1 IGF1R	9.09e-04	191	23	3	993_UP
Drug	Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; PC3; HT_HG-U133A	VPS13B IGF1R SORBS3	9.23e-04	192	23	3	7155_DN
Drug	(-)-depudecin; Up 200; 1uM; MCF7; HT_HG-U133A_EA	VPS53 ACOT8 IGF1R	9.37e-04	193	23	3	982_UP
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A	DICER1 NTRK2 IGF1R	9.37e-04	193	23	3	4321_DN
Drug	Ketoprofen [22071-15-4]; Down 200; 15.8uM; PC3; HT_HG-U133A	ABHD18 NTRK2 SORBS3	9.37e-04	193	23	3	4286_DN
Drug	Deltaline [6836-11-9]; Up 200; 7.8uM; PC3; HT_HG-U133A	IL1RL2 VPS53 SORBS3	9.37e-04	193	23	3	4306_UP
Drug	Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A	VPS13B NTRK2 SORBS3	9.37e-04	193	23	3	3474_UP
Drug	Vincamine [1617-90-9]; Up 200; 11.2uM; PC3; HT_HG-U133A	VPS53 IGF1R MLYCD	9.37e-04	193	23	3	4341_UP
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Up 200; 12.8uM; PC3; HT_HG-U133A	ABHD18 NTRK2 NTRK3	9.37e-04	193	23	3	4208_UP
Drug	Omeprazole [73590-58-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	USP7 DICER1 NTRK2	9.51e-04	194	23	3	2828_UP
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	NTRK2 SORBS3 PCIF1	9.51e-04	194	23	3	4331_DN
Drug	Demeclocycline hydrochloride [64-73-3]; Up 200; 8uM; MCF7; HT_HG-U133A	USP7 VPS13B NTRK3	9.51e-04	194	23	3	3404_UP
Drug	Racecadotril [81110-73-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	USP7 MLYCD PCIF1	9.51e-04	194	23	3	5755_DN
Drug	5155877; Up 200; 10uM; MCF7; HT_HG-U133A	USP7 VPS53 NTRK2	9.51e-04	194	23	3	6549_UP
Drug	Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A	USP7 VPS53 VPS13B	9.51e-04	194	23	3	2844_UP
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; PC3; HT_HG-U133A	VPS53 NTRK2 IGF1R	9.66e-04	195	23	3	4070_UP
Drug	Gabapentin [60142-96-3]; Up 200; 23.4uM; MCF7; HT_HG-U133A	ABHD18 VPS53 VPS13B	9.66e-04	195	23	3	3472_UP
Drug	PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A	DICER1 NTRK2 IGF1R	9.66e-04	195	23	3	6379_UP
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A	VPS53 COL14A1 NTRK2	9.66e-04	195	23	3	5884_UP
Drug	Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; MCF7; HT_HG-U133A	USP7 DICER1 NTRK2	9.66e-04	195	23	3	2833_UP
Drug	Tropine [120-29-6]; Up 200; 28.4uM; HL60; HT_HG-U133A	COL14A1 NTRK2 SORBS3	9.66e-04	195	23	3	6147_UP
Drug	Etofenamate [30544-47-9]; Up 200; 10.8uM; HL60; HT_HG-U133A	KLHL11 COL14A1 SORBS3	9.66e-04	195	23	3	2907_UP
Drug	Clomipramine hydrochloride [17321-77-6]; Down 200; 11.4uM; MCF7; HT_HG-U133A	USP7 ACOT8 PCIF1	9.66e-04	195	23	3	6825_DN
Drug	Flumethasone [2135-17-3]; Up 200; 9.8uM; PC3; HT_HG-U133A	KLHL11 VPS53 SORBS3	9.66e-04	195	23	3	4272_UP
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; HL60; HT_HG-U133A	USP7 DICER1 IGF1R	9.80e-04	196	23	3	1294_DN
Drug	Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ABHD18 DICER1 NTRK2	9.80e-04	196	23	3	2781_UP
Drug	Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A	VPS53 DICER1 COL14A1	9.80e-04	196	23	3	5689_UP
Drug	(1)-Nipecotic acid [498-95-3]; Up 200; 31uM; MCF7; HT_HG-U133A	VPS53 COL14A1 IGF1R	9.80e-04	196	23	3	5999_UP
Drug	Heliotrine [303-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A	VPS53 DICER1 SORBS3	9.80e-04	196	23	3	4739_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; MCF7; HT_HG-U133A	KCNV2 NTRK2 SORBS3	9.80e-04	196	23	3	3930_UP
Drug	Kawain [500-64-1]; Down 200; 17.4uM; PC3; HT_HG-U133A	USP7 VPS53 MLYCD	9.80e-04	196	23	3	7369_DN
Drug	Ketoconazole [65277-42-1]; Down 200; 7.6uM; PC3; HT_HG-U133A	USP7 VPS53 SORBS3	9.80e-04	196	23	3	4624_DN
Drug	Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; PC3; HT_HG-U133A	KATNA1 VPS13B PCIF1	9.80e-04	196	23	3	7141_DN
Drug	Hesperetin [520-33-2]; Up 200; 13.2uM; HL60; HG-U133A	IGF1R MLYCD PCIF1	9.80e-04	196	23	3	2031_UP
Drug	Miconazole [22916-47-8]; Down 200; 9.6uM; PC3; HT_HG-U133A	USP7 ABHD18 SORBS3	9.80e-04	196	23	3	6615_DN
Drug	Quinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A	KLHL11 VPS53 COL14A1	9.80e-04	196	23	3	3793_UP
Drug	Khellin [82-02-0]; Down 200; 15.4uM; MCF7; HT_HG-U133A	VPS53 DICER1 SORBS3	9.80e-04	196	23	3	4987_DN
Drug	Pipenzolate bromide [125-51-9]; Up 200; 9.2uM; PC3; HT_HG-U133A	USP7 ABHD18 MLYCD	9.80e-04	196	23	3	4484_UP
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A	COL14A1 NTRK2 IGF1R	9.80e-04	196	23	3	6027_UP
Drug	Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A	KLHL11 VPS13B NTRK2	9.80e-04	196	23	3	2263_UP
Drug	Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A	VPS13B NTRK2 SORBS3	9.94e-04	197	23	3	6180_UP
Drug	Hydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A	KLHL11 VPS53 COL14A1	9.94e-04	197	23	3	3621_UP
Drug	STOCK1N-28457; Up 200; 20uM; PC3; HT_HG-U133A	USP7 NTRK3 IGF1R	9.94e-04	197	23	3	6864_UP
Drug	Butamben [94-25-7]; Up 200; 20.6uM; PC3; HT_HG-U133A	COL14A1 NTRK2 TMEM143	9.94e-04	197	23	3	5792_UP
Drug	Felodipine [72509-76-3]; Up 200; 10.4uM; HL60; HT_HG-U133A	IL1RL2 NTRK2 SORBS3	9.94e-04	197	23	3	2433_UP
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	NTRK2 NTRK3 SORBS3	9.94e-04	197	23	3	6099_UP
Drug	Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A	ABHD18 DICER1 VPS13B	9.94e-04	197	23	3	2267_UP
Drug	Lincomycin hydrochloride [859-18-7]; Up 200; 9uM; MCF7; HT_HG-U133A	ABHD18 VPS53 NTRK2	9.94e-04	197	23	3	7411_UP
Drug	(d,l)-Tetrahydroberberine [522-97-4]; Up 200; 11.8uM; HL60; HT_HG-U133A	VPS13B NTRK2 SORBS3	9.94e-04	197	23	3	2163_UP
Drug	Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; HL60; HT_HG-U133A	USP7 VPS53 NTRK2	9.94e-04	197	23	3	2934_UP
Drug	Dimethisoquin hydrochloride [2773-92-4]; Down 200; 13uM; PC3; HT_HG-U133A	USP7 MLYCD SORBS3	9.94e-04	197	23	3	4207_DN
Drug	haloperidol; Up 200; 10uM; HL60; HT_HG-U133A	DICER1 VPS13B SORBS3	9.94e-04	197	23	3	6203_UP
Drug	raloxifene hydrochloride; Up 200; 0.1uM; HL60; HG-U133A	VPS13B SORBS3 PCIF1	9.94e-04	197	23	3	388_UP
Drug	Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A	ABHD18 VPS53 VPS13B	9.94e-04	197	23	3	5285_UP
Drug	S(-)Eticlopride hydrochloride [97612-24-3]; Down 200; 10.6uM; HL60; HT_HG-U133A	VPS53 COL14A1 SORBS3	9.94e-04	197	23	3	3056_DN
Drug	LY294002; Down 200; 0.1uM; MCF7; HG-U133A	NTRK2 NTRK3 SORBS3	9.94e-04	197	23	3	424_DN
Drug	Oxaprozin [21256-18-8]; Down 200; 13.6uM; PC3; HT_HG-U133A	USP7 VPS53 IGF1R	9.94e-04	197	23	3	4530_DN
Drug	Seneciphylline [480-81-9]; Up 200; 12uM; PC3; HT_HG-U133A	VPS53 COL14A1 NTRK3	9.94e-04	197	23	3	4238_UP
Drug	Pheniramine maleate [132-20-7]; Down 200; 11.2uM; HL60; HG-U133A	ABHD18 ACOT8 IGF1R	9.94e-04	197	23	3	1992_DN
Drug	Hydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; PC3; HT_HG-U133A	NTRK2 NTRK3 MLYCD	9.94e-04	197	23	3	4489_UP
Drug	Pimethixene maleate [13187-06-9]; Down 200; 9.8uM; HL60; HT_HG-U133A	ABHD18 DICER1 SORBS3	9.94e-04	197	23	3	2395_DN
Drug	DO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A	USP7 NTRK3 SORBS3	1.01e-03	198	23	3	7462_UP
Drug	Urapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; PC3; HT_HG-U133A	USP7 VPS53 MLYCD	1.01e-03	198	23	3	6696_DN
Drug	haloperidol; Up 200; 10uM; HL60; HT_HG-U133A	VPS53 VPS13B IGF1R	1.01e-03	198	23	3	6163_UP
Drug	Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; PC3; HT_HG-U133A	USP7 NTRK2 SORBS3	1.01e-03	198	23	3	2094_UP
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; HL60; HT_HG-U133A	VPS53 VPS13B PCIF1	1.01e-03	198	23	3	3081_DN
Drug	Ranitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; PC3; HT_HG-U133A	ABHD18 NTRK3 IGF1R	1.01e-03	198	23	3	2088_UP
Drug	Aztreonam [78110-38-0]; Up 200; 9.2uM; PC3; HT_HG-U133A	NTRK2 NTRK3 IGF1R	1.01e-03	198	23	3	5110_UP
Drug	Diphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A	COL14A1 VPS13B IGF1R	1.01e-03	198	23	3	4765_UP
Drug	Ethotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A	VPS53 VPS13B NTRK2	1.01e-03	198	23	3	3809_UP
Drug	Dexamethasone acetate [1177-87-3]; Up 200; 9.2uM; MCF7; HT_HG-U133A	DICER1 NTRK2 NTRK3	1.01e-03	198	23	3	2242_UP
Drug	rotenone; Down 200; 1uM; MCF7; HT_HG-U133A	VPS53 DICER1 NTRK2	1.01e-03	198	23	3	5943_DN
Drug	Antipyrine, 4-hydroxy [1672-63-5]; Up 200; 19.6uM; PC3; HT_HG-U133A	VPS53 NTRK2 IGF1R	1.01e-03	198	23	3	4095_UP
Drug	Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	USP7 COL14A1 NTRK3	1.01e-03	198	23	3	4145_UP
Disease	Lewy Body Disease	NTRK2 IGF1R	1.00e-04	22	20	2	C0752347
Disease	Carcinoma of lung	NTRK2 NTRK3	1.09e-04	23	20	2	C0684249
Disease	internet addiction disorder	NTRK2 NTRK3	2.28e-04	33	20	2	EFO_0803368
Disease	Developmental delay (disorder)	VPS53 IGF1R	2.87e-04	37	20	2	C0424605
Disease	Parkinson disease, disease progression measurement	GPR32 NTRK2	3.19e-04	39	20	2	EFO_0008336, MONDO_0005180
Disease	Alzheimer's disease (biomarker_via_orthology)	NTRK2 IGF1R	7.05e-04	58	20	2	DOID:10652 (biomarker_via_orthology)
Disease	pancreatic ductal carcinoma (is_marker_for)	NTRK3 IGF1R	7.80e-04	61	20	2	DOID:3587 (is_marker_for)
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	IGF1R MLYCD	8.85e-04	65	20	2	DOID:0080208 (biomarker_via_orthology)
Disease	susceptibility to vaginal yeast infection measurement	ABHD18 NTRK2	8.85e-04	65	20	2	EFO_0008412
Disease	Petit mal status	NTRK2 NTRK3	9.40e-04	67	20	2	C0270823
Disease	Status Epilepticus, Subclinical	NTRK2 NTRK3	9.40e-04	67	20	2	C0751522
Disease	Simple Partial Status Epilepticus	NTRK2 NTRK3	9.40e-04	67	20	2	C0751524
Disease	Non-Convulsive Status Epilepticus	NTRK2 NTRK3	9.40e-04	67	20	2	C0751523
Disease	Grand Mal Status Epilepticus	NTRK2 NTRK3	9.40e-04	67	20	2	C0311335
Disease	Complex Partial Status Epilepticus	NTRK2 NTRK3	9.40e-04	67	20	2	C0393734
Disease	Status Epilepticus	NTRK2 NTRK3	9.68e-04	68	20	2	C0038220
Disease	Malignant Glioma	NTRK2 NTRK3	1.03e-03	70	20	2	C0555198
Disease	mixed gliomas	NTRK2 NTRK3	1.03e-03	70	20	2	C0259783
Disease	Glioma	NTRK2 NTRK3	1.58e-03	87	20	2	C0017638
Disease	birth weight	KCNV2 NTRK2 IGF1R	2.36e-03	399	20	3	EFO_0004344
Disease	pneumonia, COVID-19	VPS13B NTRK3	2.64e-03	113	20	2	EFO_0003106, MONDO_0100096

Protein segments in the cluster

Peptide	Gene	Start	Entry
MEPKQMFWVRARGYI	ACOT8	201	O14734
TMRQRVSPYPFKWMD	ERVK13-1	126	Q9NX77
WRRVMLKEIYHPRML	GPR32	281	O75388
YWRRRTLMARPMIKE	ABHD18	121	Q0P651
WQVYYPMMRPLIEKF	DICER1	1831	Q9UPY3
MGMQRERYPERQLPW	ARHGAP39	896	Q9C0H5
LRMLYPRVWPYRMKV	ANKRD53	456	Q8N9V6
MRWQEMGYIFYPRKL	MT-RNR1	1	A0A0C5B5G6
MLPIRWMPPESIMYR	NTRK3	731	Q16288
VKNWMDMKRRVGPYR	MLYCD	221	O95822
RMCWQYNPKMRPSFL	IGF1R	1246	P08069
TKFWKTVRYHMPPRR	IL1RL2	526	Q9HB29
RYPMPQNLMWQKDRI	KLHL11	671	Q9NVR0
PRVWCLLRRYQMMFG	PCIF1	466	Q9H4Z3
MKIFQRKMRYWLLPP	COL14A1	1	Q05707
VLPMWMPEFFKGIRR	KATNA1	226	O75449
YKYEMMPNRTWRCRV	NKRF	366	O15226
MRFYGPQRRRLWNLM	KCNV2	236	Q8TDN2
PIRWMPPESIMYRKF	NTRK2	716	Q16620
MGEYRKMWNPREPRD	TMEM143	51	Q96AN5
PRRYVMPWKENMIFR	TEX43	46	Q6ZNM6
WYRRMFQQIHRKMPD	SORBS3	146	O60504
KYGRMFPREWCMAER	VPS53	301	Q5VIR6
MMLWRYPEPRVLTLV	VPS13B	2336	Q7Z7G8
FVRNLPWKIMVMPRF	USP7	91	Q93009