Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1D CACNA1F CACNA1S	1.51e-07	14	72	4	GO:0008331
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2	6.47e-07	46	72	5	GO:0005245
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC39A8	6.28e-06	465	72	10	GO:0046873
GeneOntologyMolecularFunction	calcium channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 TRPV2	7.13e-06	129	72	6	GO:0005262
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 TRPV2	1.75e-05	151	72	6	GO:0015085
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4	1.82e-05	152	72	6	GO:0022843
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4	5.01e-05	182	72	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4	5.32e-05	184	72	6	GO:0022832
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1C CACNA1D CACNA1F ABCC3 CACNA1S CATSPER2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC39A8	8.02e-05	758	72	11	GO:0015318
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC39A8	8.05e-05	627	72	10	GO:0022890
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	CACNA1C CACNA1D	1.27e-04	5	72	2	GO:0086007
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC39A8	1.29e-04	664	72	10	GO:0008324
GeneOntologyMolecularFunction	transporter activity	CACNA1C CACNA1D CACNA1F ABCC3 CACNA1S CATSPER2 ATP8A2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC22A24 ABCA10 SLC39A8	1.78e-04	1289	72	14	GO:0005215
GeneOntologyMolecularFunction	alpha-actinin binding	CACNA1C CACNA1D LRRC10	1.88e-04	31	72	3	GO:0051393
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2	2.35e-04	343	72	7	GO:0005261
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1C CACNA1D CACNA1F ABCC3 CACNA1S CATSPER2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC22A24 ABCA10 SLC39A8	2.73e-04	1180	72	13	GO:0022857
GeneOntologyMolecularFunction	actinin binding	CACNA1C CACNA1D LRRC10	5.00e-04	43	72	3	GO:0042805
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2 SLC13A3 SLC39A10 SLC39A8	5.32e-04	793	72	10	GO:0015075
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC39A10 SLC39A8	9.75e-04	13	72	2	GO:0140410
GeneOntologyMolecularFunction	gated channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4	1.29e-03	334	72	6	GO:0022836
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2	1.32e-03	459	72	7	GO:0005216
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH10	1.89e-03	18	72	2	GO:0008569
GeneOntologyMolecularFunction	channel activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2	2.81e-03	525	72	7	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2	2.84e-03	526	72	7	GO:0022803
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC39A10 SLC39A8	3.36e-03	24	72	2	GO:0005385
GeneOntologyBiologicalProcess	inorganic ion import across plasma membrane	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2 SLC39A10 SLC39A8	6.41e-07	142	72	7	GO:0099587
GeneOntologyBiologicalProcess	inorganic cation import across plasma membrane	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2 SLC39A10 SLC39A8	6.41e-07	142	72	7	GO:0098659
GeneOntologyBiologicalProcess	calcium ion import across plasma membrane	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2	6.86e-07	48	72	5	GO:0098703
GeneOntologyBiologicalProcess	calcium ion import into cytosol	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2	6.86e-07	48	72	5	GO:1902656
GeneOntologyBiologicalProcess	import across plasma membrane	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2 SLC39A10 SLC39A8	1.56e-05	230	72	7	GO:0098739
GeneOntologyBiologicalProcess	calcium ion import	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2	2.38e-05	98	72	5	GO:0070509
GeneOntologyBiologicalProcess	calcium ion transmembrane import into cytosol	CACNA1C CACNA1D CACNA1F CACNA1S TRPV2 EDNRA	1.11e-04	217	72	6	GO:0097553
GeneOntologyBiologicalProcess	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	CACNA1C CACNA1D	1.19e-04	5	72	2	GO:1904879
GeneOntologyBiologicalProcess	response to luteinizing hormone	TGFBR3 EDNRA	2.50e-04	7	72	2	GO:0034699
GeneOntologyBiologicalProcess	mammary gland branching involved in pregnancy	MED1 CSMD1	2.50e-04	7	72	2	GO:0060745
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 CATSPERD	1.13e-08	46	72	6	GO:0005891
GeneOntologyCellularComponent	calcium channel complex	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 CATSPERD	1.92e-07	73	72	6	GO:0034704
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1C CACNA1D CACNA1S	8.43e-06	12	72	3	GO:1990454
GeneOntologyCellularComponent	cation channel complex	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 CATSPERD KCNG4	1.64e-05	235	72	7	GO:0034703
GeneOntologyCellularComponent	T-tubule	CACNA1C CACNA1D CACNA1S EDNRA	1.60e-04	79	72	4	GO:0030315
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 CATSPERD KCNG4	3.21e-04	378	72	7	GO:0034702
GeneOntologyCellularComponent	sarcolemma	CACNA1C CACNA1D CACNA1S ANXA2 EDNRA	5.03e-04	190	72	5	GO:0042383
GeneOntologyCellularComponent	inner dynein arm	DNHD1 DNAH10	5.17e-04	10	72	2	GO:0036156
GeneOntologyCellularComponent	transporter complex	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 CATSPERD ATP8A2 KCNG4	5.96e-04	550	72	8	GO:1990351
GeneOntologyCellularComponent	CatSper complex	CATSPER2 CATSPERD	1.19e-03	15	72	2	GO:0036128
GeneOntologyCellularComponent	plasma membrane protein complex	CACNA1C CACNA1D TGFBR3 CACNA1F CACNA1S CATSPER2 CATSPERD ANXA2 KCNG4	1.45e-03	785	72	9	GO:0098797
GeneOntologyCellularComponent	FAR/SIN/STRIPAK complex	STRIP2 STRIP1	1.54e-03	17	72	2	GO:0090443
GeneOntologyCellularComponent	transmembrane transporter complex	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 CATSPERD KCNG4	2.13e-03	523	72	7	GO:1902495
Domain	VDCC_L_a1su	CACNA1C CACNA1D CACNA1F CACNA1S	1.71e-10	4	69	4	IPR005446
Domain	VDCC_a1su_IQ	CACNA1C CACNA1D CACNA1F CACNA1S	5.92e-09	7	69	4	IPR014873
Domain	GPHH	CACNA1C CACNA1D CACNA1F CACNA1S	5.92e-09	7	69	4	PF16905
Domain	GPHH_dom	CACNA1C CACNA1D CACNA1F CACNA1S	5.92e-09	7	69	4	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1D CACNA1F CACNA1S	5.92e-09	7	69	4	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1D CACNA1F CACNA1S	5.92e-09	7	69	4	PF08763
Domain	VDCCAlpha1	CACNA1C CACNA1D CACNA1F CACNA1S	3.52e-08	10	69	4	IPR002077
Domain	CAC1F_C	CACNA1C CACNA1D CACNA1F	4.83e-08	3	69	3	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1D CACNA1F	4.83e-08	3	69	3	PF16885
Domain	Channel_four-helix_dom	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4	6.37e-08	57	69	6	IPR027359
Domain	-	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4	6.37e-08	57	69	6	1.20.120.350
Domain	Ion_trans_dom	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2	2.07e-07	114	69	7	IPR005821
Domain	Ion_trans	CACNA1C CACNA1D CACNA1F CACNA1S CATSPER2 KCNG4 TRPV2	2.07e-07	114	69	7	PF00520
Domain	DUF3402	STRIP2 STRIP1	1.35e-05	2	69	2	PF11882
Domain	N1221	STRIP2 STRIP1	1.35e-05	2	69	2	PF07923
Domain	DUF3402	STRIP2 STRIP1	1.35e-05	2	69	2	IPR021819
Domain	DUF3402	STRIP2 STRIP1	1.35e-05	2	69	2	SM01293
Domain	N1221	STRIP2 STRIP1	1.35e-05	2	69	2	SM01292
Domain	N1221	STRIP2 STRIP1	1.35e-05	2	69	2	IPR012486
Domain	TLV_coat	ERVS71-1 ERVW-1	2.79e-04	7	69	2	PF00429
Domain	TLV/ENV_coat_polyprotein	ERVS71-1 ERVW-1	3.71e-04	8	69	2	IPR018154
Domain	Dynein_HC_stalk	DNHD1 DNAH10	1.19e-03	14	69	2	IPR024743
Domain	Zip	SLC39A10 SLC39A8	1.19e-03	14	69	2	PF02535
Domain	Dynein_heavy_dom-2	DNHD1 DNAH10	1.19e-03	14	69	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH10	1.19e-03	14	69	2	PF08393
Domain	MT	DNHD1 DNAH10	1.19e-03	14	69	2	PF12777
Domain	ZIP	SLC39A10 SLC39A8	1.19e-03	14	69	2	IPR003689
Domain	DHC_fam	DNHD1 DNAH10	1.37e-03	15	69	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH10	1.37e-03	15	69	2	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH10	1.37e-03	15	69	2	PF03028
Domain	-	DNHD1 ABCC3 DNAH10 N4BP2 MYO1F NDST4 ABCA10 HYDIN	6.08e-03	746	69	8	3.40.50.300
Domain	ABC_transporter_CS	ABCC3 ABCA10	1.05e-02	42	69	2	IPR017871
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S	1.92e-09	6	49	4	M47762
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	CACNA1C CACNA1D CACNA1F CACNA1S	1.26e-07	14	49	4	M47692
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S	1.09e-06	23	49	4	M47666
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1C CACNA1D CACNA1F CACNA1S	1.54e-06	25	49	4	M47948
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	CACNA1C CACNA1D CACNA1F CACNA1S EDNRA	4.74e-05	115	49	5	M9387
Pathway	WP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY	CACNA1C CACNA1D CACNA1F CACNA1S	1.24e-04	74	49	4	M39462
Pathway	KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC	CACNA1C CACNA1D CACNA1F CACNA1S	1.24e-04	74	49	4	M16376
Pathway	WP_ALZHEIMERS_DISEASE	CACNA1C CACNA1D CACNA1F CACNA1S	1.24e-04	74	49	4	MM15962
Pathway	KEGG_CARDIAC_MUSCLE_CONTRACTION	CACNA1C CACNA1D CACNA1F CACNA1S	1.60e-04	79	49	4	M17673
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	CACNA1C CACNA1D CACNA1F CACNA1S	1.93e-04	83	49	4	M8728
Pathway	KEGG_DILATED_CARDIOMYOPATHY	CACNA1C CACNA1D CACNA1F CACNA1S	2.64e-04	90	49	4	M835
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S EDNRA	3.69e-04	178	49	5	M2890
Pathway	KEGG_GNRH_SIGNALING_PATHWAY	CACNA1C CACNA1D CACNA1F CACNA1S	4.11e-04	101	49	4	M1979
Pathway	REACTOME_NCAM1_INTERACTIONS	CACNA1C CACNA1D CACNA1S	4.12e-04	42	49	3	M7169
Pathway	REACTOME_SPERM_MOTILITY_AND_TAXES	CATSPER2 CATSPERD	4.20e-04	9	49	2	M26935
Pathway	REACTOME_SPERM_MOTILITY_AND_TAXES	CATSPER2 CATSPERD	4.20e-04	9	49	2	MM14548
Pathway	REACTOME_ZINC_INFLUX_INTO_CELLS_BY_THE_SLC39_GENE_FAMILY	SLC39A10 SLC39A8	5.23e-04	10	49	2	M27361
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1C CACNA1S	6.38e-04	11	49	2	M47958
Pathway	REACTOME_ZINC_TRANSPORTERS	SLC39A10 SLC39A8	1.21e-03	15	49	2	M832
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	CACNA1C CACNA1D CACNA1S	1.35e-03	63	49	3	M11187
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	ABCC3 ALB	1.75e-03	18	49	2	M4862
Pathway	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS	ABCC3 ALB	1.95e-03	19	49	2	MM14612
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1D CACNA1F CACNA1S	1.69e-11	4	72	4	20937870
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1D CACNA1F CACNA1S	5.88e-10	7	72	4	12900400
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1D CACNA1S	8.51e-09	3	72	3	17289261
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1D CACNA1S	8.51e-09	3	72	3	17767505
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1D CACNA1S	8.51e-09	3	72	3	2173707
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA1D CACNA1F CACNA1S	2.26e-08	15	72	4	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA1D CACNA1F CACNA1S	2.26e-08	15	72	4	24453333
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1D CACNA1F CACNA1S	4.73e-07	8	72	3	28330839
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1C CACNA1F CACNA1S	7.08e-07	9	72	3	16382099
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNA1C CACNA1D CACNA1F	1.39e-06	11	72	3	18809727
Pubmed	Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.	CACNA1C CACNA1S	4.23e-06	2	72	2	25277766
Pubmed	Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.	CACNA1C CACNA1D	4.23e-06	2	72	2	20014384
Pubmed	Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.	STRIP2 STRIP1	4.23e-06	2	72	2	12588993
Pubmed	Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.	CACNA1C CACNA1D	4.23e-06	2	72	2	30001160
Pubmed	Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.	CACNA1C CACNA1D	4.23e-06	2	72	2	21352396
Pubmed	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.	CACNA1C CACNA1S	4.23e-06	2	72	2	1281468
Pubmed	Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.	CACNA1C CACNA1D	4.23e-06	2	72	2	21054386
Pubmed	Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.	CACNA1C CACNA1D	4.23e-06	2	72	2	17409250
Pubmed	Neuronal L-type calcium channels open quickly and are inhibited slowly.	CACNA1C CACNA1D	4.23e-06	2	72	2	16267232
Pubmed	Myoscape controls cardiac calcium cycling and contractility via regulation of L-type calcium channel surface expression.	CACNA1C STRIP2	4.23e-06	2	72	2	27122098
Pubmed	Beyond fusion: A novel role for ERVW-1 in trophoblast proliferation and type I interferon receptor expression.	ERVW-1 IFNAR1	4.23e-06	2	72	2	35816776
Pubmed	The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.	CACNA1C CACNA1D	4.23e-06	2	72	2	24996399
Pubmed	Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.	CACNA1D CACNA1F	4.23e-06	2	72	2	25966695
Pubmed	An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.	CACNA1C CACNA1D	4.23e-06	2	72	2	24086669
Pubmed	Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.	CACNA1C CACNA1D	4.23e-06	2	72	2	24849370
Pubmed	Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.	CACNA1C CACNA1D	4.23e-06	2	72	2	26049024
Pubmed	Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.	CACNA1C CACNA1S	4.23e-06	2	72	2	7635187
Pubmed	Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.	CACNA1C CACNA1D	4.23e-06	2	72	2	17015854
Pubmed	Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	CACNA1C CACNA1D	4.23e-06	2	72	2	19225208
Pubmed	Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.	CACNA1C CACNA1D	4.23e-06	2	72	2	16706838
Pubmed	[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].	CACNA1D CACNA1S	4.23e-06	2	72	2	21789999
Pubmed	Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.	CACNA1C CACNA1D	4.23e-06	2	72	2	23761887
Pubmed	Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.	CACNA1C CACNA1D	4.23e-06	2	72	2	14981074
Pubmed	CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.	CACNA1C CACNA1D	4.23e-06	2	72	2	25292336
Pubmed	Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.	CACNA1C CACNA1D	4.23e-06	2	72	2	17526649
Pubmed	E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR.	PDGFD HUWE1	4.23e-06	2	72	2	35472332
Pubmed	Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.	CACNA1D CACNA1S	4.23e-06	2	72	2	28978442
Pubmed	Ligand-activated signal transduction in the 2-cell embryo.	CACNA1C CACNA1D	4.23e-06	2	72	2	12606379
Pubmed	Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.	CACNA1C CACNA1D	4.23e-06	2	72	2	24941892
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.	CACNA1C CACNA1D	4.23e-06	2	72	2	24848473
Pubmed	TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.	STRIP2 STRIP1	4.23e-06	2	72	2	22298706
Pubmed	Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.	CACNA1C CACNA1D	4.23e-06	2	72	2	22826131
Pubmed	C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.	CACNA1D CACNA1F	4.23e-06	2	72	2	16921373
Pubmed	Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.	CACNA1C CACNA1D	4.23e-06	2	72	2	24470632
Pubmed	Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.	CACNA1C CACNA1D	4.23e-06	2	72	2	24760982
Pubmed	A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors.	CACNA1D TENM3 CSMD1	9.46e-06	20	72	3	35224516
Pubmed	Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.	CACNA1C CACNA1S	1.27e-05	3	72	2	9668070
Pubmed	The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.	CACNA1C CACNA1D	1.27e-05	3	72	2	19351867
Pubmed	Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.	CACNA1C CACNA1D	1.27e-05	3	72	2	21832054
Pubmed	The protein factor-arrest 11 (Far11) is essential for the toxicity of human caspase-10 in yeast and participates in the regulation of autophagy and the DNA damage signaling.	STRIP2 STRIP1	1.27e-05	3	72	2	22782902
Pubmed	Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.	CACNA1C CACNA1D	1.27e-05	3	72	2	23973784
Pubmed	MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.	CACNA1C CACNA1D	1.27e-05	3	72	2	31302118
Pubmed	Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.	CACNA1C CACNA1D	1.27e-05	3	72	2	23045342
Pubmed	Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.	CACNA1C CACNA1S	1.27e-05	3	72	2	11206130
Pubmed	Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.	CACNA1C CACNA1D	1.27e-05	3	72	2	24934288
Pubmed	mRNA for cardiac calcium channel is expressed during development of skeletal muscle.	CACNA1C CACNA1S	1.27e-05	3	72	2	8381753
Pubmed	The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs.	STRIP2 STRIP1	1.27e-05	3	72	2	30509168
Pubmed	G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.	CACNA1C CACNA1D	1.27e-05	3	72	2	26831068
Pubmed	Zinc transporters ZnT1 (Slc30a1), Zip8 (Slc39a8), and Zip10 (Slc39a10) in mouse red blood cells are differentially regulated during erythroid development and by dietary zinc deficiency.	SLC39A10 SLC39A8	1.27e-05	3	72	2	18936201
Pubmed	Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.	CACNA1C CACNA1D	1.27e-05	3	72	2	23338940
Pubmed	Genetic dissection of horizontal cell inhibitory signaling in mice in complete darkness in vivo.	CACNA1D CACNA1F	1.27e-05	3	72	2	26024096
Pubmed	Role of type I IFNs in pulmonary complications of Pneumocystis murina infection.	MED1 IFNAR1	2.53e-05	4	72	2	15843544
Pubmed	Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.	CACNA1C CACNA1D	2.53e-05	4	72	2	17110593
Pubmed	MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas.	TYRP1 MC1R	2.53e-05	4	72	2	22447455
Pubmed	The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis.	TYRP1 MC1R	4.21e-05	5	72	2	8789201
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1C CACNA1D	4.21e-05	5	72	2	15451373
Pubmed	Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.	CACNA1C CACNA1D	4.21e-05	5	72	2	31663850
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1C CACNA1D	4.21e-05	5	72	2	11296258
Pubmed	The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1.	CACNA1C CACNA1S	4.21e-05	5	72	2	1335956
Pubmed	The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function.	CACNA1D CACNA1S HUWE1	4.44e-05	33	72	3	22357600
Pubmed	Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression.	ANXA2 UGGT1 ALB HYDIN	6.15e-05	102	72	4	31623628
Pubmed	Voltage-gated calcium channels in developing GnRH-1 neuronal system in the mouse.	CACNA1C CACNA1D	6.31e-05	6	72	2	16029198
Pubmed	Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.	CACNA1C CACNA1D	6.31e-05	6	72	2	21224388
Pubmed	STRIPAK components determine mode of cancer cell migration and metastasis.	STRIP2 STRIP1	6.31e-05	6	72	2	25531779
Pubmed	New horny layer marker proteins for evaluating skin condition in atopic dermatitis.	ANXA2 ALB	6.31e-05	6	72	2	19339807
Pubmed	L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins.	CACNA1C CACNA1D	6.31e-05	6	72	2	23734214
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1C CACNA1D CACNA1F	6.81e-05	38	72	3	30786075
Pubmed	Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin.	CACNA1C CACNA1S	8.82e-05	7	72	2	9004034
Pubmed	Interaction of major coat color gene functions in mice as studied by chemical analysis of eumelanin and pheomelanin.	TYRP1 MC1R	8.82e-05	7	72	2	11277491
Pubmed	The LZT proteins; the LIV-1 subfamily of zinc transporters.	SLC39A10 SLC39A8	1.17e-04	8	72	2	12659941
Pubmed	Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma.	TYRP1 MC1R	1.17e-04	8	72	2	19710684
Pubmed	A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa.	CATSPER2 CATSPERD	1.17e-04	8	72	2	21224844
Pubmed	Dual role of laminin‑511 in regulating melanocyte migration and differentiation.	TYRP1 LAMA5	1.17e-04	8	72	2	30273664
Pubmed	Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.	ALB IFNAR1	1.17e-04	8	72	2	26588782
Pubmed	Chemical characterization of hair melanins in various coat-color mutants of mice.	TYRP1 MC1R	1.51e-04	9	72	2	7665913
Pubmed	Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.	TYRP1 MC1R	1.51e-04	9	72	2	24769727
Pubmed	Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.	ANXA2 IFNAR1	1.51e-04	9	72	2	16139798
Pubmed	Oculocutaneous Albinism and Ocular Albinism Overview	TYRP1 MC1R	1.88e-04	10	72	2	37053367
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	HUWE1 MED1	1.88e-04	10	72	2	17478428
Pubmed	The genetics of pigmentation: from fancy genes to complex traits.	TYRP1 MC1R	1.88e-04	10	72	2	8783939
Pubmed	Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.	LAMA5 ERVW-1	1.88e-04	10	72	2	21972064
Pubmed	Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.	ERVS71-1 ERVW-1	1.88e-04	10	72	2	12970426
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLEKHH1 TENM3 URB2 SLC39A10 STRIP2 STRIP1	2.02e-04	407	72	6	12693553
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1C CACNA1D CACNA1F CACNA1S	2.04e-04	139	72	4	16985003
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	CACNA1C CACNA1D TGFBR3 CACNA1S	2.27e-04	143	72	4	20424473
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	DNHD1 TGFBR3 ANXA2 GDPD3 LAMA5 SLC13A3 ALB HUWE1 STRIP1	2.45e-04	1016	72	9	19056867
Pubmed	Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.	CACNA1D CSMD1	2.75e-04	12	72	2	21901158
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVS71-1 ERVW-1	2.75e-04	12	72	2	14557543
Pubmed	Structure of a mammalian sperm cation channel complex.	CATSPER2 CATSPERD	3.25e-04	13	72	2	34225353
Pubmed	Identification of novel oocyte and granulosa cell markers.	TGFBR3 SLC39A10	3.25e-04	13	72	2	19539053
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1D CACNA1F CACNA1S	4.81e-07	26	45	4	253
GeneFamily	Cation channels sperm associated	CATSPER2 CATSPERD	1.26e-04	7	45	2	186
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	STRIP2 STRIP1	1.12e-03	20	45	2	1371
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCNX2 CACNA1F FAM187B MYO1F ALB	4.31e-06	153	70	5	8cc2667213bfac37545bb63181e88ef1f1834413
ToppCell	facs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCNX2 CACNA1F FAM187B MYO1F ALB	4.31e-06	153	70	5	596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C CACNA1F GDPD3 MYO1F SLC13A3	5.70e-06	162	70	5	71d7849108a1b59beff40e46000172c45a2f5439
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1C DNAH10 OTOGL NDST4 HYDIN	5.70e-06	162	70	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NXNL1 ANXA2 GDPD3 MYO1F GPR141	7.00e-06	169	70	5	91cfff1ad559cc327c6bb71c98aa29f0b3642568
ToppCell	droplet-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NXNL1 ANXA2 GDPD3 MYO1F GPR141	7.00e-06	169	70	5	8e5e513090e86ca29fb61dfd388014774c506914
ToppCell	droplet-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NXNL1 ANXA2 GDPD3 MYO1F GPR141	7.00e-06	169	70	5	972618e684321060c7af2429f853a6d639e8aae8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC13A3 CSMD1 SLC22A24 SLC39A8	1.00e-05	182	70	5	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ABCC3 SLC13A3 SLC22A24 HYDIN SLC39A8	1.06e-05	184	70	5	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F DNAH10 OTOGL CSMD1 HYDIN	1.06e-05	184	70	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F DNAH10 OTOGL CSMD1 HYDIN	1.06e-05	184	70	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F DNAH10 OTOGL CSMD1 HYDIN	1.06e-05	184	70	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TYRP1 OTOGL TRPV2 GPR37L1 CSMD1	1.27e-05	191	70	5	72f1ddc09080dbfea8d51294cbf7f9d4925f9cc0
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TYRP1 OTOGL TRPV2 GPR37L1 CSMD1	1.27e-05	191	70	5	6e7f589efc997f32175e0789c5ea7ca46e1389b8
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TGFBR3 SLFN12L TBC1D31 PDGFD MYO1F	1.27e-05	191	70	5	9b8b64a36e27a2523b8730c7922fd7ad865a021e
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TGFBR3 SLFN12L TBC1D31 PDGFD MYO1F	1.27e-05	191	70	5	6345c1aa0fd2f9f2154a44f9393bf7c72bb1f44e
ToppCell	droplet-Trachea-nan-3m-Epithelial-neuroendocrine_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYRP1 OTOGL TRPV2 GPR37L1 CSMD1	1.27e-05	191	70	5	3ce403e0beedb544edeb3ae6eb30267040d00c21
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C CACNA1D TENM3 ABCA10 EDNRA	1.27e-05	191	70	5	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C CACNA1D TENM3 ABCA10 EDNRA	1.30e-05	192	70	5	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D TENM3 PDGFD EDNRA	1.30e-05	192	70	5	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	Immune-natural_killer_cell\|World / Lineage, Cell type, age group and donor	TGFBR3 SLFN12L TBC1D31 PDGFD MYO1F	1.30e-05	192	70	5	68121a6ef4115a93d87aad8802ef9b27d793d8c0
ToppCell	nucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TGFBR3 SLFN12L PDGFD MYO1F GPR141	1.30e-05	192	70	5	a06d5d3c2537f8d2b1dc6b6f3e88a80b5c2a1850
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 SLFN12L TBC1D31 PDGFD MYO1F	1.33e-05	193	70	5	54604c2c5dce2ff6f3ec7ca82b595b09b8cdafe8
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D TENM3 PDGFD EDNRA	1.33e-05	193	70	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TGFBR3 SLFN12L TBC1D31 PDGFD MYO1F	1.33e-05	193	70	5	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TGFBR3 ANXA2 PDGFD MYO1F GPR141	1.36e-05	194	70	5	ecdfc27d06e363fb23f0309f26ef6404a89f14ec
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D TENM3 PDGFD EDNRA	1.36e-05	194	70	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	metastatic_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	TGFBR3 ANXA2 PDGFD MYO1F TRPV2	1.40e-05	195	70	5	bff726515ea9ce82c223e6c805000afe2e9b7206
ToppCell	(1)_T_cells-(1)_T_CD8_CTL\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TGFBR3 ANXA2 PDGFD MYO1F GPR141	1.43e-05	196	70	5	ad9b0651cb2a15b750e453b2dcf782bca08b4fe7
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C CACNA1D TGFBR3 ABCA10 EDNRA	1.43e-05	196	70	5	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 SLFN12L MTERF2 PDGFD MYO1F	1.51e-05	198	70	5	a6b942fe850e287e1cb705684e29218072daf891
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	CACNA1C CACNA1D TENM3 ABCA10 EDNRA	1.54e-05	199	70	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CACNA1D TGFBR3 TENM3 PDGFD EDNRA	1.54e-05	199	70	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C CACNA1D TENM3 ABCA10 EDNRA	1.58e-05	200	70	5	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C CACNA1D TENM3 ABCA10 EDNRA	1.58e-05	200	70	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C CACNA1D TGFBR3 TENM3 ABCA10	1.58e-05	200	70	5	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C CACNA1D NDST4 ABCA10 EDNRA	1.58e-05	200	70	5	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1F NANS ANXA2 SLC13A3	6.64e-05	138	70	4	615822e542f12aa83df1561e262b8d72bdefc60e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-MAIT\|GI_small-bowel / Manually curated celltypes from each tissue	GDPD3 TRPV2 ALB STRIP2	8.26e-05	146	70	4	1cb2e157222631e8915d89b255a843d16d7d99cc
ToppCell	metastatic_Lymph_Node-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	TGFBR3 ANXA2 MYO1F GPR141	8.71e-05	148	70	4	db046a02a00829910bf9d7dbda068e730aa78f00
ToppCell	COVID-19_Severe-multiplets\|COVID-19_Severe / disease group, cell group and cell class	TGFBR3 SLFN12L MTERF2 HYDIN	9.65e-05	152	70	4	451745151322c2fcea22dbb3dba681e12634a510
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1F ABCC3 NXNL1 SLC13A3	1.15e-04	159	70	4	c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1F SCAPER GPR141 STRIP2	1.18e-04	160	70	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ABCC3 LAMA5 SLC13A3	1.23e-04	162	70	4	2787be283b7a705647058aeb9bc54006ce5ffe95
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	DNHD1 DNAH10 CATSPERD HYDIN	1.32e-04	165	70	4	731147b4337fd0de4383dc8170b4f9ccd98caec6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CATSPERD ATP8A2 SLC13A3 CSMD1	1.39e-04	167	70	4	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S TRPV2 STRIP2 DOP1A	1.39e-04	167	70	4	f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ABCC3 LAMA5 SLC13A3	1.49e-04	170	70	4	8d3c51364a332020810836e2055c60893c10d7f3
ToppCell	facs-Marrow-T-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F MTMR4 MYO1F GPR141	1.49e-04	170	70	4	a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCell	facs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F MTMR4 MYO1F GPR141	1.49e-04	170	70	4	ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C KCNG4 CSMD1 EDNRA	1.62e-04	174	70	4	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHH1 ABCC3 HYDIN SLC39A8	1.66e-04	175	70	4	284fdc7a9d303636a637041846850d19d114861a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 SLFN12L PDGFD MYO1F	1.70e-04	176	70	4	5914e7635474e7cf24d446bdb1423bc0807ee9c6
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4\|TCGA-Lung / Sample_Type by Project: Shred V9	SLFN12L PDGFD MBOAT2 IFNAR1	1.70e-04	176	70	4	0923b01137d6f9956ca815b41102c81e82624065
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGFBR3 SLFN12L MYO1F GPR141	1.70e-04	176	70	4	6b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC13A3 CSMD1 SLC22A24	1.70e-04	176	70	4	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC13A3 CSMD1 SLC22A24	1.73e-04	177	70	4	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F ABCC3 LAMA5 SLC13A3	1.73e-04	177	70	4	4a697866ed542d3201714234cee03451adf1dcc9
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S MYO1F TRPV2 STRIP2	1.73e-04	177	70	4	3cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1\|TCGA-Liver / Sample_Type by Project: Shred V9	PCNX2 ATP8A2 PDGFD MBOAT2	1.77e-04	178	70	4	51c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell	21-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell\|Trachea / Age, Tissue, Lineage and Cell class	TGFBR3 PDGFD MYO1F TRPV2	1.77e-04	178	70	4	d2e1f6b7933b7da2682393e5ff5e03cdd8f64761
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S MYO1F TRPV2 STRIP2	1.81e-04	179	70	4	33ed9270d257895ff3b40df2c1af878119c9f492
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S MYO1F TRPV2 STRIP2	1.81e-04	179	70	4	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TENM3 ATP8A2 GPR37L1 CSMD1	1.85e-04	180	70	4	1e819c5c87704ec6535dfeaae56561895e239d07
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CACNA1C TGFBR3 MYO1F NDST4	1.85e-04	180	70	4	557453b74d4a9cc95ed1c7b9a9a58e45eb02ed6a
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C TGFBR3 TYRP1 EDNRA	1.85e-04	180	70	4	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C TYRP1 NDST4 EDNRA	1.89e-04	181	70	4	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1C CACNA1D ABCA10 EDNRA	1.89e-04	181	70	4	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYRP1 GPR37L1 CSMD1 MBOAT2	1.93e-04	182	70	4	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPIN3 CACNA1D TGFBR3 EDNRA	1.93e-04	182	70	4	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPIN3 CACNA1D TGFBR3 EDNRA	1.93e-04	182	70	4	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CACNA1C CACNA1S OTOGL EDNRA	1.93e-04	182	70	4	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	CF-Lymphoid-T_cell_&_NK_cell\|CF / Disease state, Lineage and Cell class	PCNX2 TGFBR3 SLFN12L TBC1D31	1.93e-04	182	70	4	a8dfc59a3974e3433f434676b7c2749d0fcfc8b2
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYRP1 GPR37L1 CSMD1 MBOAT2	1.93e-04	182	70	4	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TENM3 GPR37L1 CSMD1 MBOAT2	1.93e-04	182	70	4	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCC3 SLC13A3 SLC22A24 HYDIN	1.97e-04	183	70	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC13A3 CSMD1 SLC22A24	1.97e-04	183	70	4	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 ANXA2 PDGFD ALB	2.01e-04	184	70	4	10706441e7695212f95689414f31e8082b5eaf0a
ToppCell	lymphoid-T_cell-CD8+_Effector_T_cell\|T_cell / Lineage, cell class and subclass	TGFBR3 ANXA2 PDGFD MYO1F	2.01e-04	184	70	4	f610f28f8319d194871a3e94210bf1c493918986
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC13A3 SLC22A24 SLC39A8	2.01e-04	184	70	4	9434731f651820b05335085582960f08fbf895de
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC3 ANXA2 PDGFD ALB	2.01e-04	184	70	4	4bb0976a75126ad2b3deb5d2229f0716fafe200e
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C TGFBR3 PDGFD ABCA10	2.05e-04	185	70	4	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TGFBR3 SLFN12L PDGFD MYO1F	2.05e-04	185	70	4	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	TGFBR3 SLFN12L PDGFD MYO1F	2.05e-04	185	70	4	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 SLC13A3 CSMD1 SLC22A24	2.10e-04	186	70	4	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TGFBR3 TYRP1 PDGFD HYDIN	2.10e-04	186	70	4	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SLFN12L PDGFD MYO1F GPR141	2.10e-04	186	70	4	c984e5729958237b101df96d1c89a236faacded6
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	CACNA1C CACNA1D TENM3 EDNRA	2.14e-04	187	70	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 SLFN12L MTERF2 PDGFD	2.18e-04	188	70	4	f8e6247bedc0ba494c5bb551539cb8ba5a97f557
ToppCell	COPD-Lymphoid-NK\|COPD / Disease state, Lineage and Cell class	TGFBR3 SLFN12L PDGFD GPR141	2.18e-04	188	70	4	c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	CACNA1C TGFBR3 PDGFD ABCA10	2.18e-04	188	70	4	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	CF-Lymphoid-T_cell_&_NK_cell\|Lymphoid / Disease state, Lineage and Cell class	PCNX2 TGFBR3 SLFN12L TBC1D31	2.18e-04	188	70	4	15057036b46c9df621ec4955aa94ca3036245d45
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TGFBR3 SLFN12L MTERF2 PDGFD	2.18e-04	188	70	4	8155bc5476fc333bedcc78c5ddcc8e4912536caa
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGFBR3 SLFN12L PDGFD MYO1F	2.18e-04	188	70	4	1082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C TGFBR3 GPR37L1 EDNRA	2.23e-04	189	70	4	a5306561026e4dfcc39beeb785e5108ac595d136
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D TENM3 PDGFD	2.23e-04	189	70	4	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CACNA1D TENM3 PDGFD	2.23e-04	189	70	4	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	COPD-Lymphoid-NK\|World / Disease state, Lineage and Cell class	TGFBR3 SLFN12L PDGFD GPR141	2.23e-04	189	70	4	c0ac160fa7e68b92414fb1600abcac8ad1a42232
ToppCell	facs-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C TGFBR3 GPR37L1 EDNRA	2.23e-04	189	70	4	381058f55908f84375b54601d617389ef43ab855
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGFBR3 SLFN12L PDGFD MYO1F	2.23e-04	189	70	4	c604da558c9f4055fb36218452463539f2a73223
Drug	Cinnarizine	CACNA1C CACNA1D CACNA1F CACNA1S	1.08e-08	9	71	4	DB00568
Drug	Nimodipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.08e-08	9	71	4	DB00393
Drug	Mibefradil	CACNA1C CACNA1D CACNA1F CACNA1S	2.82e-08	11	71	4	DB01388
Drug	Verapamil	CACNA1C CACNA1D CACNA1F CACNA1S	1.54e-07	16	71	4	DB00661
Drug	Nilvadipine	CACNA1C CACNA1D CACNA1S	2.89e-07	5	71	3	DB06712
Drug	Nisoldipine	CACNA1C CACNA1D CACNA1S	2.89e-07	5	71	3	DB00401
Drug	KW-3049	CACNA1C CACNA1D CACNA1F CACNA1S ALB	4.86e-07	50	71	5	CID000002324
Drug	CPU-23	CACNA1C CACNA1D CACNA1S	5.77e-07	6	71	3	CID003036051
Drug	nitrendipine	CACNA1C CACNA1D CACNA1F CACNA1S ALB EDNRA	6.22e-07	98	71	6	CID000004507
Drug	Amlodipine	CACNA1C CACNA1D CACNA1S	1.01e-06	7	71	3	DB00381
Drug	Isradipine	CACNA1C CACNA1D CACNA1S	1.01e-06	7	71	3	DB00270
Drug	Nifedipine	CACNA1C CACNA1D CACNA1S	1.61e-06	8	71	3	DB01115
Drug	Nitrendipine	CACNA1C CACNA1D CACNA1S	1.61e-06	8	71	3	DB01054
Drug	CNS 1145	CACNA1C CACNA1D CACNA1F CACNA1S	3.32e-06	33	71	4	CID000190902
Drug	IHC-64	CACNA1C CACNA1D CACNA1F CACNA1S	3.32e-06	33	71	4	CID000162753
Drug	Felodipine	CACNA1C CACNA1D CACNA1S	4.71e-06	11	71	3	DB01023
Drug	mercury	CACNA1C CACNA1D CDAN1 CACNA1F ABCC3 CACNA1S ANXA2 SLC13A3 ALB EDNRA	6.75e-06	542	71	10	CID000023931
Drug	AC1L1JG6	CACNA1C CACNA1D CACNA1S	1.03e-05	14	71	3	CID000005026
Drug	manidipine	CACNA1C CACNA1D CACNA1F CACNA1S ALB	1.19e-05	95	71	5	CID000004008
Drug	FPL 64176	CACNA1C CACNA1D CACNA1S	1.29e-05	15	71	3	CID000003423
Drug	verapamil	CACNA1C CACNA1D CACNA1F ABCC3 CACNA1S KCNG4 ALB ABCA10 EDNRA	2.10e-05	490	71	9	CID000002520
Drug	Cinildipine	CACNA1C CACNA1D CACNA1F CACNA1S	2.82e-05	56	71	4	CID000002752
Drug	Bromocryptine mesylate [22260-51-1]; Up 200; 5.4uM; MCF7; HT_HG-U133A	TGFBR3 CACNA1S MYO1F EIF4G2 SCAPER ALB	3.59e-05	198	71	6	1507_UP
Drug	nilvadipine	CACNA1C CACNA1D CACNA1F CACNA1S	3.71e-05	60	71	4	CID000004494
Drug	IAA-94	CACNA1C CACNA1D CACNA1F CACNA1S	3.96e-05	61	71	4	CID000003667
Drug	fluo-3	CACNA1C CACNA1D ABCC3 CACNA1S EDNRA	3.99e-05	122	71	5	CID000104978
Drug	AC1L1DXE	CACNA1C CACNA1D CACNA1F CACNA1S ATP8A2 TRPV2 ALB	4.07e-05	299	71	7	CID000002548
Drug	lercanidipine	CACNA1C CACNA1D CACNA1F CACNA1S	4.50e-05	63	71	4	CID000065866
Drug	amlodipine	CACNA1C CACNA1D CACNA1F CACNA1S ALB	4.66e-05	126	71	5	CID000002162
Drug	NSC-686960	CACNA1C CACNA1D	5.73e-05	4	71	2	CID000192816
Drug	gallopamil	CACNA1C CACNA1D CACNA1F CACNA1S	5.74e-05	67	71	4	CID000001234
Drug	AC1L2AC7	CACNA1C CACNA1D CACNA1F CACNA1S	6.44e-05	69	71	4	CID000068733
Drug	alfacalcidol	ABCC3 ALB MED1	7.18e-05	26	71	3	ctd:C008088
Drug	AC1L1JVU	CACNA1C CACNA1D CACNA1S EDNRA	7.61e-05	72	71	4	CID000005229
Drug	CAS 298-57-7	CACNA1C CACNA1D CACNA1F CACNA1S	8.03e-05	73	71	4	CID000002761
Drug	ethosuximide	CACNA1C CACNA1D CACNA1F CACNA1S	8.47e-05	74	71	4	CID000003291
Drug	nicardipine	CACNA1C CACNA1D CACNA1F CACNA1S EDNRA	9.08e-05	145	71	5	CID000004473
Drug	B 874-67	CACNA1C CACNA1D	9.53e-05	5	71	2	CID000195466
Drug	methyl beta-aminocrotonate	CACNA1C CACNA1D	9.53e-05	5	71	2	CID000084253
Drug	nemadipine-A	CACNA1C CACNA1D	9.53e-05	5	71	2	CID002856102
Drug	nisoldipine	CACNA1C CACNA1D CACNA1F CACNA1S	1.04e-04	78	71	4	CID000004499
Drug	N-cyclopentyl-N-cyclobutylformamide	CACNA1C CACNA1D CACNA1F CACNA1S	1.09e-04	79	71	4	CID005287890
Drug	procaine	CACNA1C CACNA1D CACNA1F CACNA1S MC1R	1.17e-04	153	71	5	CID000004914
Drug	capsazepine	CACNA1C CACNA1D TYRP1 TRPV2	1.39e-04	84	71	4	CID002733484
Drug	Magnesium Sulfate	CACNA1C CACNA1S	1.43e-04	6	71	2	DB00653
Drug	valproate	CACNA1C CACNA1D TGFBR3 CACNA1F CACNA1S PCDHGA12 MC1R	1.84e-04	381	71	7	CID000003121
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1D CACNA1F CACNA1S	2.90e-11	4	70	4	DOID:0060173 (implicated_via_orthology)
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1D CACNA1F CACNA1S	1.62e-06	36	70	4	DOID:11723 (implicated_via_orthology)
Disease	Oculocutaneous albinism	TYRP1 MC1R	1.16e-04	7	70	2	cv:C0078918
Disease	pregnanediol-3-glucuronide measurement	ABCC3 SLC22A24	1.54e-04	8	70	2	EFO_0800341
Disease	Hepatomegaly	ABCC3 ALB MBOAT2	2.91e-04	54	70	3	C0019209
Disease	pigmentation disease (is_implicated_in)	TYRP1 MC1R	3.01e-04	11	70	2	DOID:10123 (is_implicated_in)
Disease	idiopathic scoliosis (implicated_via_orthology)	DNAH10 SLC39A8	6.52e-04	16	70	2	DOID:0060250 (implicated_via_orthology)
Disease	Alpha ketoglutarate measurement	TENM3 SLC13A3	6.52e-04	16	70	2	EFO_0010457
Disease	diet measurement, HOMA-B	PCNX2 SLC39A8	9.24e-04	19	70	2	EFO_0004469, EFO_0008111
Disease	Lung Injury	PDGFD ALB	1.13e-03	21	70	2	C0273115
Disease	Chronic Lung Injury	PDGFD ALB	1.13e-03	21	70	2	C2350344
Disease	HDL cholesterol change measurement	MBOAT2 ABCA10	1.48e-03	24	70	2	EFO_0007805
Disease	diet measurement, bilirubin measurement	EIF4G2 EDNRA	1.74e-03	26	70	2	EFO_0004570, EFO_0008111
Disease	psychosis predisposition measurement	CACNA1C CSMD1	1.74e-03	26	70	2	EFO_0008337
Disease	Nephrotic Syndrome	LAMA5 ALB	1.87e-03	27	70	2	C0027726
Disease	azoospermia (implicated_via_orthology)	SCAPER NDST4	1.87e-03	27	70	2	DOID:14227 (implicated_via_orthology)
Disease	Mental deterioration	NOCT IFNAR1	2.16e-03	29	70	2	HP_0001268
Disease	Carcinoma, Basal Cell	MC1R ACTRT1	2.16e-03	29	70	2	C4721806
Disease	diastolic blood pressure, unipolar depression	EIF4G2 SLC39A8	2.31e-03	30	70	2	EFO_0003761, EFO_0006336

Protein segments in the cluster

Peptide	Gene	Start	Entry
DAFIAFANLLNKPCQ	TBC1D12	606	O60347
FANLLNKPCQLAFFR	TBC1D12	611	O60347
FKEGNQLLCFQVLPR	URB2	316	Q14146
LVLIAFAQYLQQCPF	ALB	46	P02768
ECPLFKNFIIFLVFL	CATSPER2	106	Q96P56
FPAFDFQKCLVNIQA	CATSPERD	361	Q86XM0
FVLNFHAFQLKKCQP	CSMD1	2246	Q96PZ7
EIRKNIGFCPQFNFQ	ABCA10	466	Q8WWZ4
LLPFFNVLSQVFNSK	DOP1A	2396	Q5JWR5
NDFGVFLCKLFPFLQ	EDNRA	151	P25101
FLNLVQCIQNKPLYF	ANXA2	256	P07355
QQLQFIPFFKYCLLR	DNHD1	356	Q96M86
NLVPNLFLELFFVFQ	CDAN1	316	Q8IWY9
ANAFFLFIALLQQIP	ATP8A2	96	Q9NTI2
QVICFIQGNLPFKLE	PCDHGA12	381	O60330
KNLFFIGVILVCFLP	GPR141	226	Q7Z602
CFKLIQDLLSFINPQ	ABCC3	316	O15438
IFKNFNLFLALIICN	MC1R	276	Q01726
FQTFPQAVLLLFRCA	CACNA1F	1366	O60840
FKVACLSDIQQLFLP	LPIN3	741	Q9BQK8
LPIDQVNFVVCQLFA	MBOAT2	21	Q6ZWT7
IFGPCILNSFLNFIK	ERVS71-1	591	P61550
FVQAQDKCQFFQGPL	KCNG4	281	Q8TDN1
FPFLNSQDAFLKLQV	MGAT5B	716	Q3V5L5
CVFPQNVFQKGIYLL	IFNAR1	291	P17181
KLANVVFFPRCLLVQ	PDGFD	286	Q9GZP0
FIQCRLFPKFLHQNL	PCNX2	1061	A6NKB5
IPEKFFFCFLPNIIN	GDPD3	221	Q7L5L3
ALDFNNFKALPQVVC	LRRC10	81	Q5BKY1
SGVLFFLKQQSQFLC	LAMA5	2976	O15230
PLNLFNNLALKDCFV	NDST4	181	Q9H3R1
FPLFLLCLQQLAKLQ	EIF4G2	671	P78344
FVQCQPFERLFKVLL	HUWE1	621	Q7Z6Z7
LKAFVQQLFSLPCVI	KDM5A	826	P29375
LKQFPCLFEFNEAFL	MTMR4	481	Q9NYA4
LKGFLFQLCPRSIQN	MTERF2	251	Q49AM1
FFKELCSFSQALQPQ	PPP4R3C	336	Q6ZMV5
ILNLCNQSFIPAFFQ	HYDIN	826	Q4G0P3
NFQTFPQAVLLLFRC	CACNA1C	1446	Q13936
FQTFPQAVLLLFRCA	CACNA1S	1306	Q13698
FFCLPIVIFNEITKQ	GPR37L1	181	O60883
LQVFQPAVYKCFVQQ	FAM187B	276	Q17R55
KNIICQVFLPALSFN	DNAH10	141	Q8IVF4
NLILLGQLKSFFPQC	SLC13A3	256	Q8WWT9
LAFPQKFIDLLQQCT	SASS6	81	Q6UVJ0
VLQKLCQLPFQYFSD	SCAPER	1296	Q9BY12
INQGCFKFLLTFLVA	SLC39A10	431	Q9ULF5
KPFDIFILLAIFANC	CACNA1D	126	Q01668
CALFFLQNRFKLVNS	NOCT	236	Q9UK39
AFVQKLQNCTGIPLF	MED1	316	Q15648
AIFFKCQILLQFPFL	OTOGL	316	Q3ZCN5
TFVVQLPFCRKNVIN	OR13C9	161	Q8NGT0
LLLFGPCIFNLLVNF	ERVW-1	461	Q9UQF0
AFPFVKLFQNNQLIC	TBC1D31	501	Q96DN5
VFANCIPLILKFFNQ	STRIP2	601	Q9ULQ0
IAFFCITNILLFPNI	SLC22A24	21	Q8N4F4
FANCIPLILKFFNQN	STRIP1	606	Q5VSL9
IVKPLNPNFCFLQCT	NANS	171	Q9NR45
FNFPCILNKAVVNNI	ACTRT1	201	Q8TDG2
YKNCFLNLAIPIVVF	UBA6	921	A0AVT1
CIFFPLLLFQQARAQ	TYRP1	11	P17643
QCQAFVPILKDFFVR	NXNL1	46	Q96CM4
PKENQIFLFVCLFRF	SLFN12L	561	Q6IEE8
QIVLFQKLRFQFFCS	SPDYE7P	161	Q495Y7
LLIPKFFLNFLCNLI	TRPV2	386	Q9Y5S1
ALFILLQFFFQKQPS	TMCO6	341	Q96DC7
SQLFIDQPQFLKFNI	TENM3	406	Q9P273
LFKSCQLFINVPVEA	PLEKHH1	856	Q9ULM0
KFSVICPAVLQQLNF	SLC39A8	96	Q9C0K1
SPLQQNLFKFCLSLR	UGGT1	111	Q9NYU2
VFKPVFNTSLLFLQC	TGFBR3	691	Q03167
FCINFVNEKLQQIFI	MYO1F	401	O00160
KIFPAINQNFLVDIF	N4BP2	1531	Q86UW6