Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP1B STEAP1

5.87e-055492GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP1B STEAP1

5.87e-055492GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP1B STEAP1

5.87e-055492GO:0008823
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

STEAP1B STEAP1

1.23e-047492GO:0016723
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP1B

6.93e-0416492GO:0005041
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions

STEAP1B STEAP1

8.80e-0418492GO:0016722
GeneOntologyMolecularFunctioncarbohydrate binding

IGF2R P3H1 SIGLEC10 SIGLEC16 FCN3

9.52e-04310495GO:0030246
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP1B

1.20e-0321492GO:0030228
GeneOntologyMolecularFunctionsialic acid binding

SIGLEC10 SIGLEC16

1.71e-0325492GO:0033691
GeneOntologyMolecularFunctioncarboxylic acid binding

IGF2R P3H1 SIGLEC10 SIGLEC16

2.78e-03239494GO:0031406
GeneOntologyBiologicalProcessiron ion transmembrane transport

STEAP1B SLC40A1 STEAP1

4.89e-0530493GO:0034755
GeneOntologyBiologicalProcessiron ion import across cell outer membrane

STEAP1B STEAP1

5.50e-055492GO:0098706
MousePhenodiaphragmatic hernia

MET WT1 LRP1

5.95e-0529373MP:0003924
MousePhenoabnormal spleen development

WT1 SLC40A1

6.78e-055372MP:0009323
DomainDUF5050

LRP1 LRP1B

6.47e-062482IPR032485
DomainDUF5050

LRP1 LRP1B

6.47e-062482PF16472
DomainFRG2

FRG2 FRG2C

1.94e-053482PF15315
DomainFRG2

FRG2 FRG2C

1.94e-053482IPR026245
Domain-

LRP1 HHIPL1 LRP1B

1.36e-04394832.120.10.30
Domain6-blade_b-propeller_TolB-like

LRP1 HHIPL1 LRP1B

2.24e-0446483IPR011042
DomainFerric_reduct

STEAP1B STEAP1

4.20e-0412482PF01794
DomainFe3_Rdtase_TM_dom

STEAP1B STEAP1

4.20e-0412482IPR013130
DomainQuinoprot_gluc/sorb_DH

LRP1 HHIPL1

4.20e-0412482IPR011041
DomainLdl_recept_b

LRP1 LRP1B

5.77e-0414482PF00058
DomainLDLRB

LRP1 LRP1B

5.77e-0414482PS51120
DomainLY

LRP1 LRP1B

6.65e-0415482SM00135
DomainLDLR_classB_rpt

LRP1 LRP1B

6.65e-0415482IPR000033
Domainzf-CCHC

TUT7 ZCCHC2

1.58e-0323482PF00098
DomaincEGF

LRP1 LRP1B

2.02e-0326482IPR026823
Domain-

TUT7 ZCCHC2

2.02e-03264824.10.60.10
DomaincEGF

LRP1 LRP1B

2.02e-0326482PF12662
DomainHECT

HECW2 HERC1

2.18e-0327482PF00632
DomainHECTc

HECW2 HERC1

2.18e-0327482SM00119
DomainHECT_dom

HECW2 HERC1

2.18e-0327482IPR000569
DomainIPT

MET NFATC3

2.18e-0327482SM00429
DomainHECT

HECW2 HERC1

2.18e-0327482PS50237
DomainTIG

MET NFATC3

2.87e-0331482PF01833
DomainIPT

MET NFATC3

3.05e-0332482IPR002909
DomainZF_CCHC

TUT7 ZCCHC2

3.65e-0335482PS50158
DomainLDLR_class-A_CS

LRP1 LRP1B

4.74e-0340482IPR023415
DomainLdl_recept_a

LRP1 LRP1B

5.97e-0345482PF00057
Domain-

LRP1 LRP1B

6.23e-03464824.10.400.10
DomainLDLRA_1

LRP1 LRP1B

6.77e-0348482PS01209
DomainLDLRA_2

LRP1 LRP1B

7.04e-0349482PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP1B

7.04e-0349482IPR002172
DomainLDLa

LRP1 LRP1B

7.04e-0349482SM00192
DomainZnF_C2HC

TUT7 ZCCHC2

8.81e-0355482SM00343
DomainZnf_CCHC

TUT7 ZCCHC2

8.81e-0355482IPR001878
PathwayREACTOME_MET_INTERACTS_WITH_TNS_PROTEINS

MET TNS3

6.31e-055362M27775
PathwayREACTOME_MET_INTERACTS_WITH_TNS_PROTEINS

MET TNS3

6.31e-055362MM15514
Pubmed

The DNA sequence, annotation and analysis of human chromosome 3.

DNAH12 NLGN1 FRG2C FCN3

1.98e-066250416641997
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

2.03e-06250215963947
Pubmed

Inhibition of STEAP1 ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells.

STEAP1B STEAP1

2.03e-06250237209327
Pubmed

Altered Met receptor phosphorylation and LRP1-mediated uptake in cells lacking carbohydrate-dependent lysosomal targeting.

MET LRP1

2.03e-06250228724630
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

IGF2R TBC1D31 ZFYVE9 P3H1 PPM1K HERC1 RPA1 TAB3 TNS3 PCNT

2.05e-061049501027880917
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

P3H1 HECW2 LRP1 PCNX1 PPM1K HERC1 TNS3

2.27e-0642050728065597
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

IGF2R TBC1D31 NFATC3 TUT7 ZNF507 CGNL1 LRP1B TAB3 PCNT

3.13e-0685350928718761
Pubmed

SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.

SIGLEC10 SIGLEC16

6.07e-06350224859880
Pubmed

Inhibition of mouse RM-1 prostate cancer and B16F10 melanoma by the fusion protein of HSP65 & STEAP1 186-193.

STEAP1B STEAP1

6.07e-06350230841425
Pubmed

Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice.

STEAP1B STEAP1

6.07e-06350211479226
Pubmed

The role of Siglec-G on B cells in autoimmune disease and leukemia.

SIGLEC10 SIGLEC16

6.07e-06350238042621
Pubmed

The ligand-binding domain of Siglec-G is crucial for its selective inhibitory function on B1 cells.

SIGLEC10 SIGLEC16

6.07e-06350224790146
Pubmed

Six-transmembrane epithelial antigen of the prostate (STEAP1 and STEAP2)-differentially expressed by murine and human mesenchymal stem cells.

STEAP1B STEAP1

6.07e-06350219196137
Pubmed

Siglec-G is a B1 cell-inhibitory receptor that controls expansion and calcium signaling of the B1 cell population.

SIGLEC10 SIGLEC16

6.07e-06350217572677
Pubmed

Copresentation of antigen and ligands of Siglec-G induces B cell tolerance independent of CD22.

SIGLEC10 SIGLEC16

6.07e-06350223836061
Pubmed

FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients.

FRG2 FRG2C

6.07e-06350215520407
Pubmed

Siglecg limits the size of B1a B cell lineage by down-regulating NFkappaB activation.

SIGLEC10 SIGLEC16

1.21e-05450217912374
Pubmed

Replication Protein A (RPA) deficiency activates the Fanconi anemia DNA repair pathway.

FANCM RPA1

1.21e-05450227398742
Pubmed

Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo.

SIGLEC10 SIGLEC16

1.21e-05450220038598
Pubmed

CD22 x Siglec-G double-deficient mice have massively increased B1 cell numbers and develop systemic autoimmunity.

SIGLEC10 SIGLEC16

1.21e-05450220200274
Pubmed

Siglec-G regulates B1 cell survival and selection.

SIGLEC10 SIGLEC16

1.21e-05450220729333
Pubmed

Sialic Acid Ligand Binding of CD22 and Siglec-G Determines Distinct B Cell Functions but Is Dispensable for B Cell Tolerance Induction.

SIGLEC10 SIGLEC16

1.21e-05450230143587
Pubmed

Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice.

SIGLEC10 SIGLEC16

1.21e-05450224695850
Pubmed

Siglecs induce tolerance to cell surface antigens by BIM-dependent deletion of the antigen-reactive B cells.

SIGLEC10 SIGLEC16

1.21e-05450225252961
Pubmed

Siglec-G deficiency leads to more severe collagen-induced arthritis and earlier onset of lupus-like symptoms in MRL/lpr mice.

SIGLEC10 SIGLEC16

1.21e-05450224600033
Pubmed

The Steap proteins are metalloreductases.

STEAP1B STEAP1

2.02e-05550216609065
Pubmed

Epistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus.

SIGLEC10 SIGLEC16

2.02e-05550236969253
Pubmed

CD24 and Siglec-10 selectively repress tissue damage-induced immune responses.

SIGLEC10 SIGLEC16

2.02e-05550219264983
Pubmed

Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice.

SIGLEC10 SIGLEC16

2.02e-05550225987743
Pubmed

B Lymphocyte-Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury.

SIGLEC10 SIGLEC16

2.02e-05550232737150
Pubmed

The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation.

SIGLEC10 SIGLEC16

2.02e-05550227548433
Pubmed

Sialic Acid-Binding Immunoglobulin-like Lectin G Promotes Atherosclerosis and Liver Inflammation by Suppressing the Protective Functions of B-1 Cells.

SIGLEC10 SIGLEC16

2.02e-05550226947073
Pubmed

Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate.

STEAP1B STEAP1

2.02e-05550212429817
Pubmed

A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing.

SIGLEC10 SIGLEC16

2.02e-05550221623346
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

UBN1 NFATC3 PRRC2C ZNF507 CGNL1 ZCCHC2 PCNT

2.03e-0558850738580884
Pubmed

Large-scale identification of mammalian proteins localized to nuclear sub-compartments.

WT1 RPA1 PCNT

2.28e-053850311555636
Pubmed

Molecular analysis of human Siglec-8 orthologs relevant to mouse eosinophils: identification of mouse orthologs of Siglec-5 (mSiglec-F) and Siglec-10 (mSiglec-G).

SIGLEC10 SIGLEC16

3.03e-05650214559209
Pubmed

Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice.

WT1 SLC40A1

4.23e-05750215342464
Pubmed

Calcium/NFAT signalling promotes early nephrogenesis.

NFATC3 WT1

4.23e-05750221295565
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

MET DNAH12 NEB

4.34e-05475038812413
Pubmed

Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.

SIGLEC10 SIGLEC16

7.25e-05950223374343
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

MET IGF2R P3H1 LRP1

9.27e-0516450432409323
Pubmed

Genetic mutations associated with cigarette smoking in pancreatic cancer.

MET WT1 SMARCB1

1.04e-046350319351817
Pubmed

ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer.

HECW2 SLC40A1

1.10e-041150234927784
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP1B

1.10e-041150224639464
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

IGF2R TBC1D31 TUT7 ZNF507 ZCCHC2 HERC1 RPA1 PCNT

1.46e-04108450811544199
Pubmed

CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder.

SIGLEC10 SIGLEC16

1.56e-041350235921817
Pubmed

Translational animal models of autism and neurodevelopmental disorders.

MET NLGN1

1.82e-041450223226954
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP1B

1.82e-041450215082773
Pubmed

The septum transversum mesenchyme induces gall bladder development.

MET WT1

2.10e-041550223951403
Pubmed

The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver.

SIGLEC10 SIGLEC16

2.10e-041550222496360
Pubmed

Screening for replication of genome-wide SNP associations in sporadic ALS.

NLGN1 PPM1K

2.40e-041650218987618
Pubmed

A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.

FANCM RPA1

2.40e-041650220347428
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MET IGF2R P3H1 PIGX TUT7 LRP1 ERMP1 LRP1B

2.92e-04120150835696571
Pubmed

Assignment of 22 loci in the rat by somatic hybrid and linkage analysis.

MET WT1

3.05e-04185028268657
Pubmed

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.

MET WT1

3.05e-041850214628042
Pubmed

Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development.

WT1 KLK5

3.05e-041850217425782
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

PRRC2C SIGLEC10 SIGLEC16

3.53e-049550324029230
Pubmed

Genome-wide association study of chronic periodontitis in a general German population.

IGF2R NLGN1 LRP1B

3.64e-049650324024966
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK3 PRUNE2 UBN1 WT1 PCNT

3.78e-0443050535044719
Pubmed

A ubiquitin-binding protein, FAAP20, links RNF8-mediated ubiquitination to the Fanconi anemia DNA repair network.

FANCM RPA1

3.79e-042050222705371
Pubmed

ETAA1 acts at stalled replication forks to maintain genome integrity.

FANCM RPA1

4.18e-042150227723720
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP1B

4.18e-042150221337463
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TUT7 CGNL1 ZCCHC2

4.34e-0410250311214970
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PRRC2C ZNF507 NLGN1

4.60e-0410450310470851
Pubmed

Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.

MET WT1

5.03e-042350221035938
Pubmed

Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanisms.

SIGLEC10 SIGLEC16

5.48e-042450215331780
Pubmed

Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex.

WT1 PCNT

5.95e-042550219149881
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

HECW2 HERC1

6.44e-042650226949039
Pubmed

A Grhl2-dependent gene network controls trophoblast branching morphogenesis.

PLAC1 SLC40A1

6.95e-042750225758223
Pubmed

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.

WT1 PCNT

6.95e-042750226158450
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK3 PRUNE2 CGNL1 ZCCHC2 FANCM

7.03e-0449350515368895
Pubmed

Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.

MET WT1

9.17e-043150219898483
Pubmed

Placing the HIRA histone chaperone complex in the chromatin landscape.

UBN1 SMARCB1

9.17e-043150223602572
Pubmed

Human transcription factor protein interaction networks.

UBN1 NFATC3 PRRC2C ZNF507 SMARCB1 HERC1 RPA1 TAB3

9.19e-04142950835140242
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

HECW2 ZNF507 PCNX1 ERMP1 HHIPL1

9.63e-0452950514621295
Pubmed

TXLNA enhances TBK1 phosphorylation by suppressing PPM1B recruitment.

PRRC2C FANCM RPA1

1.05e-0313850337506885
Pubmed

Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

ZFYVE9 PRR14L HERC1

1.07e-0313950325476789
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

WT1 SMARCB1

1.17e-033550232504627
Pubmed

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.

IGF2R LRP1 RPA1

1.30e-0314950326370502
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

MET PRR14L PPM1K HERC1 RPA1

1.37e-0357350528330616
InteractionSIGLEC16 interactions

SIGLEC10 SIGLEC16

5.55e-062482int:SIGLEC16
GeneFamilyProteases, serine|STEAP family

STEAP1B STEAP1

3.63e-0553521324
GeneFamilyLow density lipoprotein receptors

LRP1 LRP1B

2.80e-0413352634
GeneFamilyZinc fingers CCHC-type|RNA binding motif containing

TUT7 ZCCHC2

1.06e-032535274
GeneFamilyCD molecules|C2-set domain containing|Sialic acid binding Ig like lectins

SIGLEC10 SIGLEC16

1.33e-0328352745
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SIGLEC10 SIGLEC16

2.71e-0340352592
CoexpressionBASAKI_YBX1_TARGETS_DN

PRUNE2 MET DNAH12 PDE9A HECW2 CGNL1 SLC40A1

8.76e-06398497M14877
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 NLGN1 TNS3

3.69e-081705065d5f208682be21ed58320f5fc083a7898f8712da
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 NLGN1 TNS3

5.35e-081815069d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 NLGN1 TNS3

5.53e-08182506eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 NLGN1 TNS3

5.71e-0818350692fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MET SLC44A5 ERMP1 NLGN1 TNS3

7.36e-08191506d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 MET SLC44A5 WT1 NLGN1

1.26e-06168505a086c306be430adf0632ba53e98cd8014d2de330
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 MET NLGN1 CGNL1 LRP1B

1.87e-061825059d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 NLGN1 TNS3

1.93e-06183505738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 PDE9A SLC44A5 NLGN1 TNS3

2.14e-06187505c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 CGNL1

2.14e-06187505c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 ERMP1 NLGN1 TNS3

2.20e-06188505af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 ERMP1 NLGN1 TNS3

2.25e-06189505904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 CGNL1

2.31e-061905051cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 ERMP1 CGNL1

2.31e-0619050559bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET PDE9A NLGN1 TNS3

2.76e-061975057e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 ERMP1 CGNL1 TNS3

1.75e-05138504a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

IGF2R TUT7 PCNX1 ZCCHC2

2.56e-051525042ff0980dfd8d430cca14649151d856edef115720
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MET PDE9A SLC44A5 NLGN1

4.24e-051735042e35bf2b5534a289d93a09faae660f665c131062
ToppCellControl-CD4+_T_activated|World / Disease group and Cell class

PDE9A HECW2 SIGLEC10 SLC40A1

4.24e-0517350412f8e4276b290bb388a56de4c8d8dd60415b2f63
ToppCellControl-CD4+_T_activated|Control / Disease group and Cell class

PDE9A HECW2 SIGLEC10 SLC40A1

4.33e-051745042b683e81b315ad22555314433aed5681feb48da8
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 LRP1 NLGN1 STEAP1

4.43e-051755041d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 LRP1 NLGN1 STEAP1

4.43e-05175504d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 NLGN1 TNS3

4.53e-05176504327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

PRUNE2 MET NLGN1 LRP1B

4.53e-0517650436f77d878a53b30465b0dea8333a3865dba75613
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 ERMP1 NLGN1 TNS3

4.63e-05177504da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 MET WT1 NLGN1

4.73e-05178504544379f5a6145429762258d426b876bb36c112f5
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 MET NLGN1 CGNL1

4.94e-05180504358923e4228035a3e90e2957392089219e90dcd7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 NLGN1 TNS3

5.05e-051815046956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R LRP1 PPM1K TNS3

5.16e-05182504ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 NLGN1 TNS3

5.16e-051825045e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 ERMP1 NLGN1 TNS3

5.38e-05184504da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 NLGN1 TNS3

5.61e-05186504f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 NLGN1 CGNL1 LRP1B

5.73e-05187504d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET SLC44A5 TNS3

5.85e-0518850463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R LRP1 PPM1K TNS3

5.85e-051885043f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HECW2 HHIPL1 CGNL1 FCN3

5.97e-05189504f44ddb6cdbb406b0528a9b0ba3811183ab6d1fc6
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

MET WT1 NLGN1 STEAP1

5.97e-0518950479bb2593ad5d17f94b17972884241f03a0f43770
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 PRUNE2 NLGN1 CGNL1

5.97e-051895044dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 PRUNE2 NLGN1 CGNL1

5.97e-051895040d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MET ERMP1 LRP1B

6.10e-05190504bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MET ERMP1 LRP1B

6.10e-05190504b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

MET PDE9A CGNL1 LRP1B

6.22e-05191504fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R LRP1 PPM1K TNS3

6.22e-051915043379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MET ERMP1 LRP1B

6.22e-051915042fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

MET PDE9A CGNL1 LRP1B

6.22e-051915040965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMARCB1 CGNL1 PPM1K STEAP1

6.35e-0519250480a71ab3434076803466ccac0df73468889c7dd3
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMARCB1 CGNL1 PPM1K STEAP1

6.35e-0519250475ce635d669ff77d1fd54e10467f21d5e5d67b08
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 MET SLC44A5 CGNL1

6.35e-05192504b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

SIGLEC10 LRP1 ZCCHC2 TNS3

6.48e-05193504cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLAC1 HHIPL1 LRP1B STEAP1

6.48e-05193504e5016959f24370579a8770787e96869f264cf7b3
ToppCellMS-naiveBc|MS / Condition, Cell_class and T cell subcluster

SIGLEC10 SMARCB1 PPM1K STEAP1

6.61e-05194504aa4aa0a61275610054b583f60d5d41ecc4f88a0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 MET NLGN1 CGNL1

6.61e-051945047002937e8903e037332a215d00fbc7c7843b33f2
ToppCellMS-naiveBc-|MS / Condition, Cell_class and T cell subcluster

SIGLEC10 SMARCB1 PPM1K STEAP1

6.61e-051945041757787246a7862f9709834efc62bac61d70b906
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SIGLEC10 LRP1 ZCCHC2 TNS3

6.74e-051955049d649ac7d2af313481069c95349efc0c68449e2b
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R LRP1 PPM1K TNS3

6.88e-05196504db64ab27374f82553ee577aec056141170f3656f
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

IGF2R LRP1 PPM1K TNS3

6.88e-0519650454f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

LRP1 ERMP1 SLC40A1 TNS3

6.88e-05196504cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCellE18.5-Mesenchymal-Mesenchymal_structural|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R LRP1 PPM1K TNS3

6.88e-0519650497e26622d9582b092c18ff5b7e957818f99d9631
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R LRP1 PPM1K TNS3

6.88e-05196504617103f4a09e009fe96c28eb5e40505a4fd6dcf4
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGF2R LRP1 PPM1K TNS3

6.88e-05196504f429f045ba45e24717963315832150b12a115bfa
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CGNL1 FRG2C PPM1K NEB

7.01e-051975044ea3f57cd88b8a6bb7cb4b9e3545c0fa8f331886
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 ERMP1 STEAP1B

7.01e-051975045a71e859ebe734fc70a056807b07d99fa867c687
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|World / Stress and Cell class

LRP1 ERMP1 SLC40A1 TNS3

7.01e-05197504434ae0231972acba12d06279908cf407e70511ac
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CGNL1 FRG2C PPM1K NEB

7.15e-051985044448d13511485a44fe7b549e4b8b6ad7637db624
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK3 PRUNE2 NLGN1 LRP1B

7.15e-0519850422e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellBiopsy_IPF-Mesenchymal-Mesothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

WT1 NLGN1 KLK5 STEAP1

7.44e-05200504553386523fd8f8f36617a0d81032224b7ddce442
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK3 PRUNE2 MET LRP1

7.44e-052005049d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellSepsis-Int-URO-Lymphocyte-B-B_intermediate|Int-URO / Disease, condition lineage and cell class

SMARCB1 PPM1K NEB STEAP1B

7.44e-05200504221dd8d8851c47f2202ba848de3a041b17b1db3f
ToppCellBiopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MPP4 WT1 HHIPL1 STEAP1

7.44e-05200504cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

LRP1 ERMP1 HERC1

3.47e-041225031ed865f0ecfe304fb86313ff51c04e9052357270
ToppCellmild_COVID-19-B_cell|mild_COVID-19 / disease group, cell group and cell class (v2)

PPM1K ZNF285 STEAP1

4.37e-041325034b372483bc106aecc7b96a09131e1695e54e7dc4
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

PRRC2C PCNX1 HERC1

4.67e-04135503ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 HHIPL1 NEB

4.88e-04137503dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 KLK5 LRP1B

5.09e-04139503a1945b07f177cde40e7eea03a19236ce76165857
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGF2R TUT7 PCNX1

5.41e-04142503191a13bba143ecdfc2bfd797c3ac191481388298
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SLC44A5 TNS3

5.52e-041435037a7a9829ba63468c9745904d9e993590051207ab
ToppCellmild_COVID-19-B_cell|World / disease group, cell group and cell class (v2)

PPM1K ZNF285 STEAP1

5.52e-041435034698cc877dda9b1ef7d6f18c9adc869ef791b1d8
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGF2R TUT7 PCNX1

5.52e-04143503b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC44A5 ERMP1 TNS3

5.75e-041455038da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGF2R PRRC2C TNS3

6.22e-04149503651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH12 SMARCB1 PRR14L

6.35e-0415050353de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH12 SMARCB1 PRR14L

6.35e-04150503e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

HECW2 PPM1K ZNF285

6.98e-041555037e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MPP4 HECW2 SIGLEC10

6.98e-041555035d157478669b609e1f0f0a75afd0112571fc2c46
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 ZFYVE9 LRP1

7.65e-041605030544bc465af208da448858d6e174ff56f2e08a46
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC40A1 TNS3

7.79e-0416150345591addc765760db6029ac19e80573373d1d917
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC40A1 TNS3

7.79e-041615038741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCellfacs-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 SLC40A1 TNS3

7.79e-041615039cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TUT7 ZNF507 FCN3

7.93e-04162503fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 NEB LRP1B

7.93e-04162503bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TUT7 ZNF507 FCN3

7.93e-0416250345be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCellControl-APC-like-Monocytes|Control / group, cell type (main and fine annotations)

TBC1D31 PPM1K STEAP1B

8.07e-041635034bc80a2c741d462724b6f3902377d48c57478932
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

SIGLEC10 LRP1 ZNF285

8.22e-04164503057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

LRP1 PPM1K TNS3

8.22e-04164503519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell3'_v3-Lung-Lymphocytic_B-ABC_aged-B_memory|Lung / Manually curated celltypes from each tissue

HECW2 LINC01599 SMARCB1

8.22e-041645037766900740f67dbbe3c4d90fbfdcc1665cee6515
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 MPP4 SLC40A1

8.36e-04165503af59a095ecc6758abc13d763c00e44447c488167
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 MET SLC44A5

8.36e-0416550382530f96aaefe28a13bad0474bbad043f127a86c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LINC01599 PPM1K STEAP1B

8.36e-041655037039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 MET SLC44A5

8.36e-041655030c714e852f912b5749de4cb0895406673979b2e6
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 MPP4 SLC40A1

8.36e-0416550384eca6a0f5e996b6955ae79fa102af239098fe8f
DiseaseHEPATOCELLULAR CARCINOMA

MET IGF2R

8.13e-059452114550
DiseaseHepatocellular carcinoma

MET IGF2R

8.13e-059452cv:C2239176
Diseaseasthma

DOCK3 PIGX LRP1 ERMP1 STEAP1B LRP1B PCNT

1.32e-04751457MONDO_0004979
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

WT1 LRP1

1.49e-0412452DOID:3827 (implicated_via_orthology)
Diseasecardiotoxicity, response to anthracycline-based chemotherapy

PRUNE2 MPP4

2.05e-0414452EFO_0005257, EFO_1001482
Diseasenephroblastoma (is_implicated_in)

IGF2R WT1

2.05e-0414452DOID:2154 (is_implicated_in)
Diseaseatopic asthma

PIGX LRP1 ERMP1 STEAP1B

2.41e-04199454EFO_0010638
DiseaseCongenital hernia of foramen of Morgagni

IGF2R WT1

3.83e-0419452C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF2R WT1

3.83e-0419452C0265700
DiseaseCongenital diaphragmatic hernia

IGF2R WT1

4.69e-0421452C0235833
DiseaseFEV/FEC ratio

MET DNAH12 PDE9A TUT7 LRP1 HHIPL1 HERC1 NEB

4.81e-041228458EFO_0004713
Diseasehepatocellular carcinoma (is_marker_for)

MET IGF2R SMARCB1 LRP1B

1.14e-03301454DOID:684 (is_marker_for)
Diseasetongue squamous cell carcinoma (is_marker_for)

MET FANCM

1.46e-0337452DOID:0050865 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
AQHAVLANCHFDSVA

ERMP1

196

Q7Z2K6
DFVNQCHDPNEAAHA

PPM1K

311

Q8N3J5
CHDPNEAAHAVTEQA

PPM1K

316

Q8N3J5
DDSHPVHVDNCILNA

P3H1

581

Q32P28
HHDSQVCSNGPVSED

HECW2

361

Q9P2P5
ADHDSSNSNCAVIVH

FCN3

236

O75636
EDDHPHVLALDECQN

LRP1B

2316

Q9NZR2
EHDEDAGVVCSHQNP

HHIPL1

766

Q96JK4
DNSDEAPALCHQHTC

LRP1

881

Q07954
DEPSLCDCDVHKHNQ

FANCM

1076

Q8IYD8
NGHNSDCASSPVVHE

HERC1

2541

Q15751
PHSAIFCHDEDSSDQ

PCNX1

591

Q96RV3
NDISPLENHHCAVAF

PDE9A

376

O76083
ECAHEACNVHNLQPV

DNAH12

1496

Q6ZR08
DHVIVNDSLHDACAQ

MPP4

596

Q96JB8
HVLANNDVSCDHPSN

KLK5

26

Q9Y337
HCQTDQVPAWADAAH

NLGN1

531

Q8N2Q7
QEACVHQDTQAHHAL

PCNT

2776

O95613
NNETSVMPCEDDHHL

RPA1

281

P27694
TAVHNSEIQETCDAH

FRG2C

131

A6NGY1
AVHNSEIQETCDAHH

FRG2

131

Q64ET8
QHPNHPDDAILQCDA

DOCK3

1401

Q8IZD9
VENHPEVAAHTSCLQ

LINC01599

76

Q8WXQ3
DQECAIHADNVNRHE

CGNL1

316

Q0VF96
CHSAPGHQEENKNDF

CENPJ

111

Q9HC77
HCIHENQTCDPEIFN

SLC44A5

411

Q8NCS7
SCAHEMESVADHEPN

PRR14L

1151

Q5THK1
FPHNHTADIQSEVHC

MET

146

P08581
NEHDDCQVTNPSTGH

IGF2R

1511

P11717
CVFSEEEHTQVPCHQ

PLAC1

166

Q9HBJ0
EEHTQVPCHQAGAQE

PLAC1

171

Q9HBJ0
QEINAAVEHAENPCH

TBC1D31

976

Q96DN5
VCDHPDTAFTHAEEN

PRUNE2

1966

Q8WUY3
NPDILTHCEHDSNSQ

PRUNE2

2086

Q8WUY3
QADIHDTQAAAADEH

TAB3

651

Q8N5C8
DVRPHHTDANNQSAC

PRRC2C

881

Q9Y520
LCFDDHDPAVIHENA

SMARCB1

166

Q12824
SNIHELEHEQEPTCA

SLC40A1

271

Q9NP59
TDNVCHLFAEHDPEQ

TNS3

1411

Q68CZ2
LHQTAHADEFDCPSE

STEAP1

46

Q9UHE8
HADEFDCPSELQHTQ

STEAP1

51

Q9UHE8
AHADEFDCPSELQHA

STEAP1B

31

Q6NZ63
QHPEHCVTSADQHSA

ZCCHC2

551

Q9C0B9
AHSEVAAPCALENED

PIGX

186

Q8TBF5
AEPHEEQCLSAFTVH

WT1

81

P19544
ISPNCHQELDAHEDD

NFATC3

116

Q12968
EAHVVNDHDNDANIH

ZNF507

171

Q8TCN5
AGEQHQDCEPAAAAV

UBN1

31

Q9NPG3
HISVHPENSDCIQAD

TUT7

716

Q5VYS8
PQDHNTDLTCHVDFS

SIGLEC10

206

Q96LC7
TQLGNHDSDPETCHV

ZSCAN5C

31

A6NGD5
NCGVAFADDTDPHVH

ZNF285

236

Q96NJ3
HSAPLTTEEEDHCAN

ZFYVE9

76

O95405
SPQDHDTDLTCHVDF

SIGLEC16

206

A6NMB1
DAVPFVHAHHCNDVQ

NEB

4231

P20929