Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainIG

CNTN5 CEACAM7 ROBO2 FCRL4 KIR2DS5 CNTN6

8.69e-04421506SM00409
DomainIg_sub

CNTN5 CEACAM7 ROBO2 FCRL4 KIR2DS5 CNTN6

8.69e-04421506IPR003599
Domainfn3

CNTN5 ROBO2 IL2RG CNTN6

9.21e-04162504PF00041
DomainFN3

CNTN5 ROBO2 IL2RG CNTN6

1.50e-03185504SM00060
DomainIg_I-set

CNTN5 CEACAM7 ROBO2 CNTN6

1.66e-03190504IPR013098
DomainI-set

CNTN5 CEACAM7 ROBO2 CNTN6

1.66e-03190504PF07679
DomainIG_LIKE

CNTN5 CEACAM7 ROBO2 FCRL4 KIR2DS5 CNTN6

1.91e-03491506PS50835
DomainFN3

CNTN5 ROBO2 IL2RG CNTN6

1.96e-03199504PS50853
DomainIg-like_dom

CNTN5 CEACAM7 ROBO2 FCRL4 KIR2DS5 CNTN6

2.16e-03503506IPR007110
DomainFN3_dom

CNTN5 ROBO2 IL2RG CNTN6

2.35e-03209504IPR003961
DomainIg-like_fold

CNTN5 CEACAM7 ROBO2 FCRL4 KIR2DS5 IL2RG CNTN6

2.60e-03706507IPR013783
DomainIGc2

CNTN5 ROBO2 FCRL4 CNTN6

3.58e-03235504SM00408
DomainIg_sub2

CNTN5 ROBO2 FCRL4 CNTN6

3.58e-03235504IPR003598
Domain-

OVGP1 HPSE2

3.95e-03355023.20.20.80
DomainGlyco_hydro_catalytic_dom

OVGP1 HPSE2

4.64e-0338502IPR013781
Domain-

CNTN5 CEACAM7 ROBO2 FCRL4 IL2RG CNTN6

8.24e-036635062.60.40.10
DomainGlycoside_hydrolase_SF

OVGP1 HPSE2

8.87e-0353502IPR017853
DomainRhoGAP

ARHGAP10 RACGAP1

1.20e-0262502SM00324
DomainRhoGAP

ARHGAP10 RACGAP1

1.24e-0263502PF00620
DomainRHOGAP

ARHGAP10 RACGAP1

1.27e-0264502PS50238
DomainRhoGAP_dom

ARHGAP10 RACGAP1

1.27e-0264502IPR000198
Domain-

ARHGAP10 RACGAP1

1.27e-02645021.10.555.10
Pubmed

Decreased Expression of Synaptophysin 1 (SYP1 Major Synaptic Vesicle Protein p38) and Contactin 6 (CNTN6/NB3) in the Cerebellar Vermis of reln Haplodeficient Mice.

RELN CNTN6

7.09e-06354231098770
Pubmed

Glycosylphosphatidylinositol anchored recognition molecules that function in axonal fasciculation, growth and guidance in the nervous system.

CNTN5 CNTN6

1.42e-0545421838307
Pubmed

Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.

CNTN5 CNTN6

2.36e-05554227539848
Pubmed

The role of Robo3 in the development of cortical interneurons.

RELN ROBO2

3.54e-05654219366869
Pubmed

Two regions within the proximal steroidogenic factor 1 promoter drive somatic cell-specific activity in developing gonads of the female mouse.

GATA4 ETS2

4.94e-05754220962249
Pubmed

Efficient generation of B lymphocytes by recognition of self-antigens.

IGLV2-14 IL2RG

4.94e-05754221604259
Pubmed

Mig-6 controls EGFR trafficking and suppresses gliomagenesis.

PCCA IL2RG COPS5

5.12e-054654320351267
Pubmed

SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.

SENP1 IL2RG

1.06e-041054222284677
Pubmed

GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium.

CBLIF GATA4

1.29e-041154234111600
Pubmed

A role for Nr-CAM in the patterning of binocular visual pathways.

CNTN5 CNTN6

1.55e-041254216701205
Pubmed

A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.

AKAP6 CNTN6

1.83e-041354221079607
Pubmed

Pioneering axons regulate neuronal polarization in the developing cerebral cortex.

CNTN5 CNTN6

1.83e-041354224559674
Pubmed

Role of Rb during Neurogenesis and Axonal Guidance in the Developing Olfactory System.

RELN ROBO2

2.45e-041554227667971
Pubmed

Mash1 is required for neuroendocrine cell development in the glandular stomach.

CBLIF GATA4

2.80e-041654218173746
Pubmed

PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors.

IGLV2-14 IL2RG

3.17e-041754211869689
Pubmed

Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation.

RELN ROBO2

3.17e-041754217376983
Pubmed

Wnt/β-catenin promotes gastric fundus specification in mice and humans.

CBLIF GATA4

3.56e-041854228052057
Pubmed

Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.

ARHGAP10 DNAAF10 CNTN5

3.90e-049154322610502
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PRUNE2 ZNF793 SENP1 ARHGAP10 BTAF1 PATL1 PCCA COPS5 ALG12

4.40e-04148954928611215
Pubmed

FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.

RELN ROBO2

4.42e-042054230392794
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

RELN ROBO2

4.42e-042054229961574
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PRR12 TUBGCP3 MARF1 RACGAP1 BTAF1 PATL1

5.02e-0465054638777146
Pubmed

ETS-dependent regulation of a distal Gata4 cardiac enhancer.

GATA4 ETS2

6.39e-042454222056786
Pubmed

Robo1 modulates proliferation and neurogenesis in the developing neocortex.

NFYC ROBO2

8.10e-042754224741061
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

PRR12 MARF1 BTAF1 MED13L

8.51e-0427254431010829
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

RELN ROBO2 CNTN6

1.01e-0312654316284245
Pubmed

A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.

CNTN5 GATA4

1.14e-033254223049088
Pubmed

High-resolution recombinational map of mouse chromosome 16.

IGLV2-14 ETS2

1.21e-03335429244437
Pubmed

Multiple roles of epithelial heparan sulfate in stomach morphogenesis.

CBLIF GATA4

1.36e-033554229700203
Pubmed

Axon guidance genes control hepatic artery development.

CEACAM7 ROBO2

1.44e-033654237497580
Pubmed

Human transcription factor protein interaction networks.

PRR12 NFRKB MARF1 NFYC GATA4 RACGAP1 PATL1 PCCA

1.54e-03142954835140242
GeneFamilyFibronectin type III domain containing

CNTN5 ROBO2 IL2RG CNTN6

2.79e-04160364555
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 DNAH2 ROBO2 HPSE2 CSMD3

1.90e-08146526c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 ROBO2 HPSE2 CSMD3 CNTN6

3.66e-0816352619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellCOVID-19-kidney-Technical/muscle|kidney / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 ROBO2 HPSE2 CSMD3

8.26e-071485250dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 ROBO2 HPSE2 CSMD3

1.18e-061595255335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 HPSE2 CSMD3

1.52e-0512852491072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

RELN ROBO2 HPSE2 CSMD3

1.57e-0512952457b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PRUNE2 CNTN5 HPSE2 CSMD3

2.10e-05139524a1945b07f177cde40e7eea03a19236ce76165857
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 HPSE2 CSMD3

2.10e-0513952464c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MS4A18 HPSE2 CSMD3 CNTN6

2.48e-0514552496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 HPSE2 CSMD3

2.69e-05148524d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RELN CNTN5 HPSE2 CSMD3

2.84e-051505240205318a870e091add66ee4305747dda9f51510d
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MS4A18 HPSE2 CSMD3 CNTN6

3.83e-05162524bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CNTN5 ETS2 MED13L CSMD3

6.56e-0518652423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 PRUNE2 ROBO2 HPSE2

6.83e-05188524293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

AKAP6 ROBO2 HPSE2 CSMD3

6.98e-05189524203c80030df08ae112f9ae4043709f455d87ce89
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP6 ARHGAP10 ROBO2 HPSE2

6.98e-051895242cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP6 ARHGAP10 ROBO2 HPSE2

6.98e-05189524127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN CNTN5 GATA4 CNTN6

7.27e-05191524156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RELN GATA4 HPSE2 CSMD3

7.56e-05193524cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

KANSL1L NHSL1 MED13L PCCA

8.35e-051985241996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 ARHGAP10 HPSE2

8.35e-05198524bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 ARHGAP10 HPSE2

8.35e-05198524c12e7511628db819a52959bb68580e27c00c2e41
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 ARHGAP10 HPSE2

8.51e-05199524b1753474152b82a0b811b9878c890a359e14919a
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 PRUNE2 ROBO2 HPSE2

8.68e-05200524f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 PRUNE2 ROBO2 HPSE2

8.68e-05200524dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
Diseasecaudate nucleus measurement, functional brain measurement, response to reward

CSMD3 NPFFR1 CNTN6

6.23e-0547483EFO_0007849, EFO_0008387, EFO_0008396
Diseaseatrial fibrillation

AKAP6 ARHGAP10 CNTN5 GATA4 PCCA

3.36e-04371485EFO_0000275
Diseasecomparative body size at age 10, self-reported

AKAP6 RELN ROBO2 MED13L NPFFR1

5.91e-04420485EFO_0009819
Diseaseresponse to vaccine, cytokine measurement

ARHGAP10 DNAAF10 CNTN5

1.28e-03131483EFO_0004645, EFO_0004873
DiseaseParoxysmal atrial fibrillation

AKAP6 ARHGAP10 GATA4

2.11e-03156483C0235480
DiseasePersistent atrial fibrillation

AKAP6 ARHGAP10 GATA4

2.11e-03156483C2585653
Diseasefamilial atrial fibrillation

AKAP6 ARHGAP10 GATA4

2.11e-03156483C3468561
DiseaseAtrial Fibrillation

AKAP6 ARHGAP10 GATA4

2.26e-03160483C0004238
Diseasedimethylglycine measurement

CNTN5 CSMD3

2.56e-0346482EFO_0010476
DiseaseMyopia

AKAP6 GATA4 HPSE2 MED13L

3.53e-03385484HP_0000545
Diseaseprostate carcinoma, type 2 diabetes mellitus

AKAP6 OSBPL7

4.18e-0359482EFO_0001663, MONDO_0005148

Protein segments in the cluster

PeptideGeneStartEntry
SWQSESLPVSLSASQ

BCL2L13

246

Q9BXK5
WVNTLSSSSLLTNAD

COPS5

246

Q92905
SSTSNQLWLEFNSDT

CSMD3

1321

Q7Z407
LSTANLPNSSSTLGW

CAPS2

86

Q9BXY5
SNKSWDLLIPQASSN

FCRL4

146

Q96PJ5
TASLLTFWNLPNSAQ

CEACAM7

21

Q14002
NTVLNKSSNWGTSPL

ALG12

246

Q9BV10
TLSASSPSWLGAAQN

CNTN5

61

O94779
SSWPLSQNGTNTEAT

NPFFR1

11

Q9GZQ6
QWLNPQSPTTTSSNS

ARHGAP10

686

A1A4S6
SSDPATESTQNNQWT

PATL1

701

Q86TB9
NLDELSSSSSWLLNQ

KANSL1L

521

A0AUZ9
VNIARPSSQQSSWTS

HDX

86

Q7Z353
PSSQQSSWTSANNDV

HDX

91

Q7Z353
ISSNNRQTLPCVSWS

MED13L

1246

Q71F56
QSSPASSLNSWFSAA

NFRKB

406

Q6P4R8
SISTSVSYQAPNNTW

ERVS71-1

371

P61550
LTSASSWISNLPNNS

LIPJ

56

Q5W064
NVTLSTQPISSLDWS

DNAAF10

316

Q96MX6
GSWAQSALTQPASVS

IGLV2-23

16

P01705
PASSDFSDLNTQTNW

NHSL1

181

Q5SYE7
FESSDSLLQSWNSQS

ETS2

286

P15036
STAAQSQLTAALTSW

LMLN2

211

A0A1B0GTW7
SRLAWTLTANQPSSQ

TUBGCP3

201

Q96CW5
NVTSTWNLASPLLSV

PCCA

591

P05165
NPNNSWNSSSALSLL

HPSE2

231

Q8WWQ2
SSSDAQQSLQSFWPR

NFYC

11

Q13952
SWQLVQTQCLPSSSN

RELN

3151

P78509
LLVSVTGNSSNSWPS

KIR2DS5

216

Q14953
QSPQTSSKQDSWNSL

GATA4

416

P43694
LLWATAGTSTQTQSS

CBLIF

11

P27352
LFTLLSTQDQNSSSW

BTAF1

541

O14981
STQDQNSSSWLIPIL

BTAF1

546

O14981
STTSQLSWRAGPDNN

CNTN6

611

Q9UQ52
NPGLTHTSNSSQWNT

MS4A18

121

Q3C1V0
SWNNITDSLDPATLS

GLMP

156

Q8WWB7
ASRQVSPLLASQSWS

MARF1

741

Q9Y4F3
SQSWSSRSMSPNLLN

MARF1

751

Q9Y4F3
NCTWNSSSEPQPTNL

IL2RG

71

P31785
AQSVLQSLPSSQWSV

DNAH2

2426

Q9P225
WAQSNTTAQCLPSLA

SLC13A2

571

Q13183
SLPQFWLSSAVNSSS

OVGP1

391

Q12889
QSSKPSSAQQASELW

OSBPL7

16

Q9BZF2
GSWAQSALTQPASVS

IGLV2-14

16

P01704
NDSSVALSSWGQQPS

PRUNE2

1551

Q8WUY3
SQNSSLWAQLSSTQT

TEDC2

216

Q7L2K0
SALPSWAFANLSSLQ

LRTM2

81

Q8N967
GQWRNSTPSSSSSLQ

SENP1

96

Q9P0U3
SWSISLPSNNCTKNV

SHLD3

131

Q6ZNX1
LVWNTQSSSLQATPS

IMPG2

396

Q9BZV3
ASSLLSQFRSPSWQT

PRR12

106

Q9ULL5
TLQPWNSDSTLNSRQ

RACGAP1

251

Q9H0H5
SWNAKLQLQSETSSS

AKAP6

561

Q13023
STDLFSSIQSPSNWN

ZNF793

126

Q6ZN11
DSWPATSLPVNNSNS

ROBO2

926

Q9HCK4
SRNSSSAWPNLTSQE

ZSCAN22

226

P10073
SPNILNNSMSSWSQL

TRPM7

1591

Q96QT4
LSPAQTSQVTSLSSW

ZNF554

101

Q86TJ5