Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity IgG receptor activity

FCGR1A FCGR1BP

1.96e-052892GO:0019771
GeneOntologyMolecularFunctionleukotriene receptor binding

FCGR1A FCGR1BP

1.96e-052892GO:0031774
GeneOntologyMolecularFunctionIgG receptor activity

FCGR1A FCGR1BP

4.07e-047892GO:0019770
GeneOntologyBiologicalProcessadaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

RFTN1 RNF168 FCGR1A FCGR1BP AGER SOCS5 PAXIP1 CD70 CD74 IRF4

3.33e-054629010GO:0002460
GeneOntologyBiologicalProcessmale mating behavior

HDAC4 NCOA1 GRN

3.52e-0515903GO:0060179
GeneOntologyBiologicalProcesspositive regulation of phagocytosis, engulfment

FCGR1A FCGR1BP AGER

6.25e-0518903GO:0060100
GeneOntologyBiologicalProcesspositive regulation of membrane invagination

FCGR1A FCGR1BP AGER

6.25e-0518903GO:1905155
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TET2 KMT2C ZNF142 USF3 ALX1 HDAC4 KLF10 BRCA1 CSRNP3 CIITA NFKBIA PAXIP1 NCOA1 IRF4 KAT6B AGRN CRTC2

9.37e-0513909017GO:0045944
GeneOntologyBiologicalProcesspositive regulation of neuron apoptotic process

NF1 HDAC4 AGER GRN AGRN

1.21e-04110905GO:0043525
GeneOntologyBiologicalProcessregulation of phagocytosis, engulfment

FCGR1A FCGR1BP AGER

1.52e-0424903GO:0060099
GeneOntologyBiologicalProcessregulation of membrane invagination

FCGR1A FCGR1BP AGER

1.72e-0425903GO:1905153
GeneOntologyBiologicalProcesstype III hypersensitivity

FCGR1A FCGR1BP

1.87e-045902GO:0001802
GeneOntologyBiologicalProcessregulation of type III hypersensitivity

FCGR1A FCGR1BP

1.87e-045902GO:0001803
GeneOntologyBiologicalProcesspositive regulation of type III hypersensitivity

FCGR1A FCGR1BP

1.87e-045902GO:0001805
GeneOntologyBiologicalProcessregulation of immune response

RFTN1 FCGR1A FCGR1BP AGER INPPL1 SOCS5 NFKBIA PAXIP1 CD74 IRF4 LAMP2 GRN ZNRF4 BTN2A1

2.45e-0410859014GO:0050776
MousePhenoabnormal macrophage antigen presentation

FCGR1A FCGR1BP CIITA

1.18e-0510663MP:0002454
Pubmed

Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.

FCGR1A FCGR1BP CD74

1.90e-07594332970988
Pubmed

Human transcription factor protein interaction networks.

SOX5 TET2 EPC2 KMT2C KLF10 AGO3 BRCA1 NFKBIA PAXIP1 XRN1 SUGP1 NCOA1 IRF4 GRN FIGN

6.56e-061429941535140242
Pubmed

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

FCGR1A FCGR1BP

7.23e-06294228814603
Pubmed

Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.

FCGR1A FCGR1BP

7.23e-06294237733444
Pubmed

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

FCGR1A FCGR1BP

7.23e-0629429257847
Pubmed

The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.

FCGR1A FCGR1BP

7.23e-06294225231998
Pubmed

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.

FCGR1A FCGR1BP

7.23e-06294230190171
Pubmed

Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.

FCGR1A FCGR1BP

7.23e-0629422136886
Pubmed

Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia.

TET2 KMT2C

7.23e-06294226880370
Pubmed

FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.

FCGR1A FCGR1BP

7.23e-06294230552619
Pubmed

Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.

FCGR1A FCGR1BP

7.23e-06294235833115
Pubmed

Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.

FCGR1A FCGR1BP

7.23e-06294215528358
Pubmed

Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.

FCGR1A FCGR1BP

7.23e-06294214991835
Pubmed

Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.

FCGR1A FCGR1BP

7.23e-0629421402657
Pubmed

Mouse FcgammaRI: identification and functional characterization of five new alleles.

FCGR1A FCGR1BP

7.23e-06294210752630
Pubmed

Neuronal FcγRI mediates acute and chronic joint pain.

FCGR1A FCGR1BP

7.23e-06294231211699
Pubmed

Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways.

CIITA NCOA1

7.23e-06294212933903
Pubmed

Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.

FCGR1A FCGR1BP

7.23e-06294216849450
Pubmed

CD64 plays a key role in diabetic wound healing.

FCGR1A FCGR1BP

7.23e-06294238524127
Pubmed

The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules.

CIITA CD74

7.23e-0629428294875
Pubmed

Developmentally ordered appearance of a functional Fc gamma receptor on TCR V gamma 3 thymocytes. Evidence for stimulation-induced expression.

FCGR1A FCGR1BP

7.23e-0629428077658
Pubmed

Modulating IgG effector function by Fc glycan engineering.

FCGR1A FCGR1BP

7.23e-06294228289219
Pubmed

Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice.

FCGR1A FCGR1BP

7.23e-06294235273604
Pubmed

IgG3-mediated enhancement of the antibody response is normal in Fc gammaRI-deficient mice.

FCGR1A FCGR1BP

7.23e-06294216305642
Pubmed

Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

FCGR1A FCGR1BP

7.23e-06294221124939
Pubmed

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.

FCGR1A FCGR1BP

7.23e-06294224430180
Pubmed

Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity.

FCGR1A FCGR1BP

7.23e-06294238885133
Pubmed

Germline mutations in NF1 and BRCA1 in a family with neurofibromatosis type 1 and early-onset breast cancer.

NF1 BRCA1

7.23e-06294223624750
Pubmed

Novel Fc gamma receptor I family gene products in human mononuclear cells.

FCGR1A FCGR1BP

7.23e-0629421430234
Pubmed

The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.

FCGR1A FCGR1BP

7.23e-06294215835266
Pubmed

Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.

FCGR1A FCGR1BP

7.23e-0629428663283
Pubmed

Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.

FCGR1A FCGR1BP

7.23e-0629421830050
Pubmed

Functional characteristics of the high affinity IgG receptor, FcγRI.

FCGR1A FCGR1BP

7.23e-06294221325219
Pubmed

FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo.

FCGR1A FCGR1BP

7.23e-0629428611682
Pubmed

Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.

FCGR1A FCGR1BP

7.23e-06294216409296
Pubmed

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.

FCGR1A FCGR1BP

7.23e-06294230744065
Pubmed

Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata.

FCGR1A FCGR1BP

7.23e-06294217124586
Pubmed

Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice.

FCGR1A FCGR1BP

7.23e-0629428480181
Pubmed

The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D.

NF1 BRCA1

7.23e-0629428566965
Pubmed

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

FCGR1A FCGR1BP

7.23e-06294229576375
Pubmed

Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.

FCGR1A FCGR1BP

7.23e-06294218245810
Pubmed

Biochemical characterization of murine Fc gamma RI.

FCGR1A FCGR1BP

7.23e-0629428478020
Pubmed

FcγR-binding affinity of monoclonal murine IgG1s carrying different N-linked Fc oligosaccharides.

FCGR1A FCGR1BP

7.23e-06294231554601
Pubmed

RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1.

RNF168 BRCA1

7.23e-06294223055523
Pubmed

The involvement of FcR mechanisms in antibody-mediated rejection.

FCGR1A FCGR1BP

7.23e-06294218049118
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RFTN1 USF3 ATP13A1 TMCC2 SOCS5 ZFP28 SSH2 PTGFRN UNC80

7.87e-0649394915368895
Pubmed

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.

FCGR1A FCGR1BP

2.16e-05394216841095
Pubmed

Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.

FCGR1A FCGR1BP

2.16e-05394222003208
Pubmed

Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells.

FCGR1A FCGR1BP

2.16e-05394212594281
Pubmed

Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression.

FCGR1A FCGR1BP

2.16e-05394215880819
Pubmed

A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies.

FCGR1A FCGR1BP

2.16e-05394228924242
Pubmed

IRF-4-mediated CIITA transcription is blocked by KSHV encoded LANA to inhibit MHC II presentation.

CIITA IRF4

2.16e-05394224204280
Pubmed

FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.

FCGR1A FCGR1BP

2.16e-05394222493081
Pubmed

Neurofibromatosis with male breast cancer--risk factor or co-incidence? Report of two rare cases.

NF1 BRCA1

2.16e-05394225267367
Pubmed

Escherichia coli K1 induces pterin production for enhanced expression of Fcγ receptor I to invade RAW 264.7 macrophages.

FCGR1A FCGR1BP

2.16e-05394224161960
Pubmed

FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.

FCGR1A FCGR1BP

2.16e-05394219657115
Pubmed

Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection.

FCGR1A FCGR1BP

2.16e-05394233032297
Pubmed

Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1.

FCGR1A FCGR1BP

2.16e-0539429763663
Pubmed

Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity.

FCGR1A FCGR1BP

2.16e-05394230297432
Pubmed

FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.

FCGR1A FCGR1BP

2.16e-05394212875993
Pubmed

An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells.

RNF168 BRCA1

2.16e-05394224829461
Pubmed

Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells.

FCGR1A FCGR1BP

2.16e-05394212427132
Pubmed

Expression of CD64, CD206, and RAGE in adherent cells of diabetic patients infected with Mycobacterium tuberculosis.

FCGR1A AGER

2.16e-05394218279703
Pubmed

MicroRNA-127 inhibits lung inflammation by targeting IgG Fcγ receptor I.

FCGR1A FCGR1BP

2.16e-05394222287715
Pubmed

Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice.

FCGR1A FCGR1BP

2.16e-05394223898046
Pubmed

Bridging channel dendritic cells induce immunity to transfused red blood cells.

CIITA IRF4

2.16e-05394227185856
Pubmed

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses.

CIITA CD74

2.16e-05394232855215
Pubmed

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization.

FCGR1A FCGR1BP

2.16e-0539429892619
Pubmed

Residual LCMV antigen in transiently CD4+ T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory.

FCGR1A FCGR1BP

2.16e-05394230636035
Pubmed

Cutting Edge: Drebrin-Regulated Actin Dynamics Regulate IgE-Dependent Mast Cell Activation and Allergic Responses.

FCGR1A FCGR1BP

2.16e-05394226056254
Pubmed

The essential role of complement in antibody-mediated resistance to Salmonella.

FCGR1A FCGR1BP

2.16e-05394230179254
Pubmed

The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21.

FCGR1A FCGR1BP

2.16e-0539428697799
Pubmed

Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of the BCR, TLRs and FcγR.

FCGR1A FCGR1BP

2.16e-05394223728777
Pubmed

The lysosomal protein cathepsin L is a progranulin protease.

LAMP2 GRN

2.16e-05394228743268
Pubmed

FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways.

FCGR1A FCGR1BP

2.16e-05394216543474
Pubmed

Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA.

CIITA IRF4

2.16e-05394223776173
Pubmed

Dichotomous ovarian cancer-initiating potential of Pax8+ cells revealed by a mouse genetic mosaic model.

NF1 BRCA1

2.16e-05394237207276
Pubmed

Both Fcgamma receptor I and Fcgamma receptor III mediate disease in accelerated nephrotoxic nephritis.

FCGR1A FCGR1BP

2.16e-05394212707052
Pubmed

FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas.

CIITA CD74

2.16e-05394226500140
Pubmed

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes.

FCGR1A FCGR1BP

2.16e-05394228432146
Pubmed

Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity.

FCGR1A FCGR1BP

4.32e-0549429551950
Pubmed

E47, IRF-4, and PU.1 synergize to induce B-cell-specific activation of the class II transactivator promoter III (CIITA-PIII).

CIITA IRF4

4.32e-05494215242870
Pubmed

miR-138 activates NF-κB signaling and PGRN to promote rheumatoid arthritis via regulating HDAC4.

HDAC4 GRN

4.32e-05494231492495
Pubmed

Signaling through mutants of the IgA receptor CD89 and consequences for Fc receptor gamma-chain interaction.

FCGR1A FCGR1BP

4.32e-05494216517729
Pubmed

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal.

FCGR1A FCGR1BP

4.32e-05494229511065
Pubmed

Human immunoglobulin G hinge regulates agonistic anti-CD40 immunostimulatory and antitumour activities through biophysical flexibility.

FCGR1A FCGR1BP

4.32e-05494231562320
Pubmed

Fc receptor regulation of protective immunity against Chlamydia trachomatis.

FCGR1A FCGR1BP

4.32e-05494211872097
Pubmed

Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcgamma receptors and expression of monokines.

FCGR1A FCGR1BP

4.32e-0549429490697
Pubmed

Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo.

FCGR1A FCGR1BP

4.32e-05494216455953
Pubmed

The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma.

FCGR1A FCGR1BP

4.32e-05494216452176
Pubmed

Mouse immune thrombocytopenia is associated with Th1 bias and expression of activating Fcγ receptors.

FCGR1A FCGR1BP

4.32e-05494228028748
Pubmed

Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens.

FCGR1A FCGR1BP

4.32e-05494212898452
Pubmed

Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.

FCGR1A FCGR1BP

4.32e-05494219996316
Pubmed

Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.

TET2 IRF4

4.32e-05494227869616
Pubmed

Association of CNK1 with Rho guanine nucleotide exchange factors controls signaling specificity downstream of Rho.

CNKSR1 MAP3K10

4.32e-05494215753034
Pubmed

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease.

FCGR1A FCGR1BP

4.32e-05494212705859
Pubmed

Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome.

RNF168 BRCA1

4.32e-05494221552324
Pubmed

Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine.

FCGR1A FCGR1BP

4.32e-05494216585547
Pubmed

C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors.

FCGR1A FCGR1BP

4.32e-05494217182593
Pubmed

NOD2 ligation subverts IFN-alpha production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation.

NFKBIA IRF4

4.32e-05494219890047
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 CNKSR1 NHS CD70 CTNNA2 POF1B

1.59e-0616994630141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TET2 RFTN1 CIITA CD58 CD74 IRF4

3.53e-06194946bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCellCOVID_non-vent|World / Disease condition, Lineage, Cell class and subclass

KLF10 FCGR1A FCGR1BP NFKBIA CD74 GRN

4.21e-06200946accef1050963dc91e189ac3d38228f15bf57e06e
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF136 FCGR1A FCGR1BP CIITA CD74

1.41e-05145945778655fffd73df101e656154a41b478a1b695116
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 CNKSR1 NHS CTNNA2 POF1B

2.79e-05167945cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EPC2 CIITA ATP13A1 ZNF761 RASL12

3.21e-05172945da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellNS-critical-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RFTN1 CIITA CD70 CD74 IRF4

3.68e-05177945d4db058c09012ec9fbde61277a9f86d9956de8fc
ToppCellNS-moderate-d_16-33-Lymphoid-B_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SOX5 RFTN1 CIITA CD70 IRF4

3.68e-05177945320fd77c7c98e9305dcc34a168ec9d674539ed65
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

CNKSR1 IL17RE AGER HRH4 ANKRD18A

4.54e-05185945c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellmoderate-Lymphoid-B_cell|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SOX5 RFTN1 CIITA CD70 IRF4

4.66e-05186945fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D19 OXR1 NHS CUBN FIGN

5.16e-05190945989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOX5 RFTN1 CD70 CD74 IRF4

5.16e-051909450db545a4cba7534bad2693e0d565cde7dbc7a586
ToppCellControl-Myeloid-cDC2|Control / Disease state, Lineage and Cell class

TET2 RFTN1 CIITA CD74 IRF4

5.16e-051909454e481e42353d47af7991744000403af2873f6a41
ToppCellIPF-Myeloid-cDC2|World / Disease state, Lineage and Cell class

TET2 RFTN1 CIITA CD74 IRF4

5.29e-051919459fda87fb6bc5b8b6c0214ec909ebbc9f3f65319b
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

TET2 RFTN1 CIITA CD74 IRF4

5.29e-051919454e4887175200a57e1b041f2f131e3df774df3509
ToppCelltumor_Lung-Myeloid_cells-Alveolar_Mac|tumor_Lung / Location, Cell class and cell subclass

FCGR1A FCGR1BP CD74 LAMP2 GRN

5.42e-0519294544eda67501e69799c5981be602c143d12f5f222f
ToppCellIPF-Myeloid-cDC2|IPF / Disease state, Lineage and Cell class

TET2 RFTN1 CIITA CD74 IRF4

5.42e-05192945fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCellmoderate-Lymphoid-B_cell|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SOX5 RFTN1 CIITA CD74 GRN

5.42e-05192945ae3727503c3b9f4695e565fd3161cc33b898f349
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Monocytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

KLF10 FCGR1A FCGR1BP NFKBIA GRN

5.56e-05193945ddbd8944661ac3b0b5fe63471bdc24ba05598017
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FCGR1A FCGR1BP CIITA CD70 CD74

5.83e-05195945c707885d092aedbbe14f51f7de4a5911c9214289
ToppCell356C-Myeloid-Dendritic-cDC2|356C / Donor, Lineage, Cell class and subclass (all cells)

TET2 CIITA CD74 IRF4 GRN

5.83e-051959454c9a2167d8cfe40dfd609c303ada5b5ef800bd8f
ToppCellhealthy_donor-Myeloid-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

KLF10 CIITA CD74 GRN PTGFRN

5.98e-05196945ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGR1A CD58 CD74 LAMP2 GRN

5.98e-05196945173d2c38a01c9ae1c50657d5fc383238aed4aacb
ToppCellhealthy_donor-Myeloid-Dendritic-cDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

KLF10 CIITA CD74 GRN PTGFRN

5.98e-05196945aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCellIIH-granulo1-|IIH / Condition, Cell_class and T cell subcluster

FCGR1A NHS CD74 RCBTB2 GRN

6.12e-0519794551be6d5652b17c70f3a33f244efc3b728ec56f5b
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGR1A CD58 CD74 LAMP2 GRN

6.12e-051979454f022bae7af2ca23689cc0d35046a7e23dba6e9c
ToppCellsystemic_lupus_erythematosus-managed-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

KLF10 FCGR1A NFKBIA CD74 GRN

6.12e-051979455a81796c813bab9f8b7aedfd5e3a6a58c257837b
ToppCellIIH-granulo1|IIH / Condition, Cell_class and T cell subcluster

FCGR1A NHS CD74 RCBTB2 GRN

6.12e-0519794539637e8b726bc58c0a6885c49713111f97aff881
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGR1A CD58 CD74 LAMP2 GRN

6.12e-0519794569671ed173057a67265ac39ed03fbd57dbd22c5c
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TET2 CIITA CD58 CD74 IRF4

6.12e-05197945a902aa05e5f711bcfdd9e19749ab636b597eb116
ToppCellCOVID-19_Moderate-Classical_Monocyte|World / disease group, cell group and cell class

TET2 KLF10 FCGR1A FCGR1BP GRN

6.12e-0519794516cf3939e700aef1e16159f0652ba2dfad287e7a
ToppCell390C-Myeloid-Dendritic|390C / Donor, Lineage, Cell class and subclass (all cells)

TET2 CIITA CD74 IRF4 GRN

6.12e-05197945424526c94b9a73c1c28ddc65dfba53aba5c6b2d2
ToppCellSigmoid-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

TET2 RNF168 TMCC2 XRN1 HRH4

6.27e-05198945305d7ae9b070ac7211638a5282374c02bf13af40
ToppCellParenchyma_COVID-19-Immune-TX-MoAM-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

STRADB OXR1 CD58 BAMBI GRN

6.27e-05198945a7eed9eeb728a8796e2780090cc244856efd8c65
ToppCellBLOOD--(3)_Intermediate_monocytes| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KLF10 FCGR1A FCGR1BP CD74 GRN

6.27e-0519894561685a86f70a7d2a6d3260b76081119978c15661
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCGR1A FCGR1BP CIITA GAB3 CD74

6.42e-05199945744b63fba33b176ab7dde11646ccb313665505f7
ToppCellsevere-B_memory|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CIITA CD70 GSX2 CD74 POF1B

6.42e-051999456d3436dd65d525aaa23ec02672005380f21c4d0f
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 KMT2C NF1 NCOA1 SSH2

6.42e-0519994594b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

FCGR1A FCGR1BP NFKBIA CD74 GRN

6.42e-0519994560e6312a149e23e4b486d92fb1f9625960b69c9d
ToppCellSevere-B_intermediate-6|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SOX5 TET2 CIITA CD74 GRN

6.42e-05199945bf6ebb63ab361d9d1946225894d7be433e9befab
ToppCell390C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RFTN1 CIITA CD74 IRF4 GRN

6.58e-052009453935b6ff3ae32d170a268538c756ee34ed2308d4
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KLF10 FCGR1A FCGR1BP CD74 GRN

6.58e-05200945465ed50e0b92bb8c27ffe56d816f063a45b52be9
ToppCellCOVID_non-vent-Myeloid|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KLF10 FCGR1A FCGR1BP CD74 GRN

6.58e-05200945a40768e8e58c86b8e20bc188b9274ebe412fc765
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

SOX5 NF1 CSRNP3 CTNNA2 KAT6B

6.58e-052009452a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellCOVID_non-vent-Myeloid-Monocytic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

KLF10 FCGR1A FCGR1BP CD74 GRN

6.58e-052009454243a9d32f3a11141284d0d944cb81194b532876
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TBC1D19 USF3 NHS BAMBI

1.43e-0412594443aa4b77dccf0ea2979218826af16034f2017c3a
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-4|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

IL17RE HRH4 ANKRD18A AGRN

1.47e-04126944ef456fb97c28bc234431f70bd935994225bfbf21
ToppCellLPS_only-Myeloid-Dendritic_cells-mDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RFTN1 CD70 CD74 IRF4

2.65e-0414794426bd9d89e2e7b841cc18030bb7cebb642b987183
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CIITA DLEC1 PRR14L CUBN

2.87e-0415094453de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CIITA DLEC1 PRR14L CUBN

2.87e-04150944e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFTN1 CIITA SZT2 CD74

3.02e-04152944cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCellPND01-Immune-Immune_Myeloid-DC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFTN1 CIITA SZT2 CD74

3.02e-04152944c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFTN1 CIITA SZT2 CD74

3.02e-04152944c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CIITA CD74 IRF4 LINC00528

3.25e-041559449f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

RFTN1 IRF4 DLEC1 PTGFRN

3.25e-04155944d76a0f99ec35560d18820f9c92b69364ef2250e3
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 TMCC2 NAV3 HRH4

3.33e-041569445caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 TMCC2 NAV3 HRH4

3.33e-04156944758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCellCOVID-19-Myeloid-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

TET2 CIITA DSCR8 CD74

3.33e-04156944a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RFTN1 ZFP28 HRH4 IRF4

3.58e-041599441dde4d19cc0fde7ebbccb4c31bb845a92206021b
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRH CIITA CD74 POF1B

3.66e-04160944e9e52532131cdc3fb01e81cfc046e3f670cc8e75
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

KLF10 AGER TMCC2 AGRN

3.75e-041619441973b112d8d67aacc02751797d0148e7b53bfa66
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRCA1 NHS IRF4 PTGFRN

3.84e-04162944b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP XRN1 RCBTB2

3.93e-04163944d005115aa1e1458b51de7eb719794617a4168608
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1BP BAMBI GRN CTNNA2

4.02e-0416494417d5b8bb7c015cf9f0d6e578a0d212eada39cb93
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 FCGR1BP CIITA CD74

4.02e-04164944758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TBC1D19 USF3 NHS BAMBI

4.02e-04164944d6806deabf5f5c355934387be2baae125ac33fb8
ToppCellAdult-Immune-dendritic_cell|Adult / Lineage, Cell type, age group and donor

RFTN1 CIITA CD74 IRF4

4.11e-04165944073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE9 CD74 IRF4 CUBN

4.21e-041669444b31d2755108b2815316411a38bfb11fd30ef98a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNKSR1 FIGN MUC5AC ZNF443

4.21e-0416694460060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNKSR1 FIGN MUC5AC ZNF443

4.21e-04166944ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF10 FCGR1A FCGR1BP GRN

4.21e-0416694428a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNKSR1 FIGN MUC5AC ZNF443

4.21e-041669444586d6725403f879fc96f67be579022587ce1906
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF10 FCGR1A FCGR1BP GRN

4.21e-041669442a04915d534a83e65aa168435d6856125b5bdd78
ToppCellThalamus-Macroglia-POLYDENDROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

BRCA1 SYDE2 INPPL1 MROH2B

4.31e-041679441e144c03409df94ccd39760842590e8ea7487e29
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FCGR1A NAV3 CD74 GRN

4.31e-04167944942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

RFTN1 NAV3 GAB3 PZP

4.31e-04167944d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCellnormal_Lung-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

NAV3 NHS CD70 CD74

4.40e-0416894476b49463895cdef27c90f831c6246bcb92b9761b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SOCS5 ZNF778 ZNF761 CUBN

4.40e-04168944ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

SOX5 RFTN1 CIITA CD74

4.40e-04168944494d5a11154ff22fedb25f4036d730cef376da60
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA CD70 CD74 IRF4

4.50e-04169944d44fc49056799dfc70a3c7d538c210d88ffded05
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP RCBTB2 GRN

4.50e-04169944d4bd489ebdb86e70ed5e3dbbe8518c6cae2197e5
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD18A DLEC1 PZP CDHR4

4.50e-0416994414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSRNP3 NFKBIA CUBN UNC80

4.50e-0416994412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellwk_08-11-Hematologic_Lymphocytic-B-Late_pro-B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CIITA CD74 IRF4 LINC00528

4.60e-04170944ad69ebfda452e19eedc453e1d07dacb844d64e47
ToppCelldroplet-Lung-nan-21m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC3 CIITA CD74 IRF4

4.60e-0417094471c52fadecc6b4bfe98692b266adaa1406f6d56d
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 PTPRH IL17RE POF1B

4.60e-04170944a121e10099faaeb60251eec162f38caf7c4238c2
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA CD74 GRN CUBN

4.60e-0417094429deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA CD74 GRN CUBN

4.60e-04170944dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIITA CD70 CD74 IRF4

4.60e-0417094453fd50c9a27d47662fbcbd7e9e9837f72ac448c5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1BP IL17RE BAMBI CTNNA2

4.71e-0417194487d652afbb375f8ee50e5faecf6085630cd2163c
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SZT2 NAV3 DLEC1 RASL12

4.81e-04172944de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCelldroplet-Liver|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD74 LAMP2 GRN PZP

4.81e-04172944cd0e8f48836a16026b47ade06abadf26b53f581f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF10 FCGR1A DSCR8 GRN

4.81e-04172944c32e6af9e2d29da47b5d870207b598cff11aef6c
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF10 FCGR1A NHS GRN

4.81e-041729440b247fe57163af08132db8df42e6757699885295
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF10 FCGR1A DSCR8 GRN

4.81e-041729441a0556c97fcba126126c22adea5235d977d41ebe
ToppCell367C-Myeloid-Dendritic-cDC_activated|367C / Donor, Lineage, Cell class and subclass (all cells)

RFTN1 CIITA TMCC2 IRF4

4.92e-0417394494f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

FCGR1A FCGR1BP GRN UNC80

4.92e-041739444efa0878ed1ede8fa5d6c191a76d4f70558ba761
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

OR51D1 FCGR1A FCGR1BP SSH2

5.03e-04174944eaaf17a06efc09ed4752b449827b1f0f424d3dad
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFTN1 CIITA CD70 IRF4

5.13e-04175944393da565f61ba640410419a0cabaaf5c1056580a
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFTN1 CIITA CD70 IRF4

5.13e-04175944271b56d4ab940959d28ca4b86ce2750350dfc717
DiseaseCongenital myasthenic syndrome ib

GRN AGRN

2.94e-053932C1850792
DiseaseIntellectual Disability

KMT2C CNKSR1 ZNF142 NF1 HDAC4 BRCA1 OXR1 CTNNA2

8.62e-05447938C3714756
Diseasegas trapping measurement

AGER BAMBI DLEC1

1.04e-0429933EFO_0007628
Diseasepeak expiratory flow

SOX5 TET2 HDAC4 AGER XRN1 NCOA1 DLEC1 SSH2

1.81e-04498938EFO_0009718
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

HDAC4 AGER NFKBIA IRF4

2.18e-0493934DOID:3525 (biomarker_via_orthology)
DiseaseLeukemia, Myelocytic, Acute

TET2 KMT2C NF1 BRCA1 AGRN

2.24e-04173935C0023467
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

TET2 KMT2C BRCA1

3.91e-0445933DOID:3748 (is_implicated_in)
Diseasefemoral neck bone mineral density

PCNX2 USF3 ALX1 CSRNP3 CTNNA2

3.98e-04196935EFO_0007785
DiseasePeripheral T-Cell Lymphoma

TET2 CD58

4.35e-0410932C0079774
DiseaseMalignant neoplasm of breast

NF1 HDAC4 BRCA1 ARFGAP3 NFKBIA NCOA1 NHS CD74 DLEC1 CUBN KAT6B

5.64e-0410749311C0006142
DiseaseGlobal developmental delay

ZNF142 OXR1 SZT2 CTNNA2

8.45e-04133934C0557874
Diseasediffuse large B-cell lymphoma

NCOA1 IRF4

8.72e-0414932EFO_0000403
Diseasenasopharynx carcinoma (is_implicated_in)

TET2 BRCA1

1.00e-0315932DOID:9261 (is_implicated_in)
Diseasenevus count

HDAC4 IRF4

1.45e-0318932EFO_0004632
Diseaseprostate cancer (is_marker_for)

KMT2C AGER NFKBIA NCOA1

1.52e-03156934DOID:10283 (is_marker_for)
Diseasestomach cancer (is_implicated_in)

TET2 KMT2C BRCA1

1.54e-0372933DOID:10534 (is_implicated_in)
Diseaseglaucoma (is_marker_for)

RFTN1 MUC5AC

1.80e-0320932DOID:1686 (is_marker_for)
Diseaselung non-small cell carcinoma (is_marker_for)

NF1 BRCA1 AGER BAMBI

2.04e-03169934DOID:3908 (is_marker_for)
Diseaseacute myeloid leukemia (is_implicated_in)

TET2 NF1 DLEC1

2.40e-0384933DOID:9119 (is_implicated_in)
Diseasestomach carcinoma (is_marker_for)

KMT2C BRCA1

2.59e-0324932DOID:5517 (is_marker_for)
DiseaseNoonan Syndrome

NF1 KAT6B

2.59e-0324932C0028326

Protein segments in the cluster

PeptideGeneStartEntry
HHVRLERTSPCQDSS

ALX1

61

Q15699
SCHSLSERGLHSPSQ

C2orf16

1621

Q68DN1
HSPSERSHCSPSERS

C2orf16

1751

Q68DN1
GHTTTNHLIPALCTS

EPC2

701

Q52LR7
SLIHLVGPSDCTLHS

ACOT7L

151

Q6ZUV0
IDCSGSHRSLGVHLS

ARFGAP3

46

Q9NP61
SISESPLEGTSHCHI

ANKRD18A

636

Q8IVF6
SHSHSPTLCRAVCQL

CIITA

606

P33076
SSIPVETHRALASCH

ATP13A1

561

Q9HD20
CDLVHTRCITPTGTH

GRN

171

P28799
THQISLHVASAGPCE

AGRN

586

O00468
THTGTDPGRTTHRLC

LINC00528

16

Q8N1L1
LCSHAGIQGTSRPSH

AGO3

751

Q9H9G7
TLAICSSTTASRHHP

CD70

111

P32970
PNHHLSGSCTITIEV

CDHR4

526

A6H8M9
TNHGLVPCHISTNLS

RCBTB2

136

O95199
CVATHSSHGPQESRA

AGER

301

Q15109
HQAPLTARHGLASCT

RASL12

206

Q9NYN1
AGTLPCGHTETITAH

PZP

461

P20742
ASHSRALVGICTGHS

RFTN1

541

Q14699
RPSEERICHAVSTSH

KAT6B

26

Q8WYB5
HGGTVDPTFTSRCTH

PAXIP1

636

Q6ZW49
LHCEVLHLPGSSSTQ

FCGR1BP

41

Q92637
STCGSHTVPSLHAGL

FIGN

166

Q5HY92
TPTHVTAACAVSRGH

MAP3K10

811

Q02779
SSLPCGQDSTITHGH

KMT2C

3566

Q8NEZ4
SSSSHPEHAGRIQSI

HDAC4

671

P56524
ILTTCIPSSGHSRHR

CD58

201

P19256
LTTSSPEGCRISHGH

IRF4

266

Q15306
LSNCETGRLHHTSLP

GAB3

186

Q8WWW8
TGRLHHTSLPTRCDS

GAB3

191

Q8WWW8
AGASLCSVPHRTTDV

LRRC3

191

Q9BY71
GNSSHVECPHQTGSL

IL17RE

346

Q8NFR9
PTLNGCHSEISAHSS

CSRNP3

286

Q8WYN3
PRLVLSGHTHSACEV

MPPE1

296

Q53F39
CPLCVTSHLHSSRGS

GSX2

61

Q9BZM3
PLRCSSRGQSITSHH

PCNX2

141

A6NKB5
HPLRHASVLTGCTVA

OR51D1

141

Q8NGF3
TTGSQHCSSRPLELT

NAV3

31

Q8IVL0
PNTTHSTGSCRSHTA

LAMP2

256

P13473
GVLTQSCTTPHLHSI

NFKBIA

161

P25963
TQGTHTTLVTRNCHP

MUC5AC

1731

P98088
PISTHIGNELCHSGS

POF1B

221

Q8WVV4
SLHGPQETLDRTVHC

MCAT

106

Q8IVS2
TPGHLRSDTEHSTNE

OXR1

391

Q8N573
VEPCGTNTHASSLQH

BRCA1

271

P38398
SLTHCSSLLEAPQGH

CUBN

2711

O60494
IQSGTCQHPTSHVSL

KLHL11

336

Q9NVR0
GRASQLSTHLPTCAE

CTNNA2

831

P26232
RNHSGTTIPTLECCH

BAMBI

86

Q13145
GVCSIQSSPHREHIL

DPH7

241

Q9BTV6
THCSRHGSGPNIILT

CRTC2

606

Q53ET0
HTTSPTQRHLCGGSI

F11

406

P03951
CSGSITDHCSLHLPV

DSCR8

36

Q96T75
ATVGENTTLRCHLSP

BTN2A1

41

Q7KYR7
LHCEVLHLPGSSSTQ

FCGR1A

41

P12314
IDSSRIRSHICSHPG

KLF10

361

Q13118
PNTRSRGHHNCSESL

CD74

261

P04233
QPCSGVLSELVTTHH

DLEC1

1491

Q9Y238
HGPSVCSFEISSLHS

PRR14L

1891

Q5THK1
LHPISTSHSCAETPR

FAM149B1

426

Q96BN6
ELRCTAASASPLHTH

PTGFRN

166

Q9P2B2
HLSRCQSHPGLTAVS

HRH4

206

Q9H3N8
CREVHHTDILPSGNT

SYDE2

566

Q5VT97
HIHSSPGRSTCLRQT

SZT2

1726

Q5T011
LHQHQCRPRSSSTTD

TMCC2

211

O75069
AHDPCVFHSSTVTGL

SOCS5

441

O75159
PIHCISTAGVLLSSH

NHS

606

Q6T4R5
CPSSHSSLTERHKIL

NCOA1

676

Q15788
TQCSIHSPSSSSRHL

GAS8-AS1

106

O95177
ASHLPHLTRTLATSC

INPPL1

201

O15357
LPSHSDIHISCLTGL

WDR17

1266

Q8IZU2
SSPSTHHIGVCSLAR

MROH2B

1236

Q7Z745
SPLGLEIHTTSNCQH

CNKSR1

206

Q969H4
HPGEITNAHNSSCIS

SUGP1

66

Q8IWZ8
HQRIHTGESSTCPSL

ZFP28

831

Q8NHY6
QTSSLTCHRRLHTGE

ZNF761

281

Q86XN6
HCSGQREAISSHPLQ

nan

31

Q6ZSR3
CTSSGLTEHVRTHTG

ZNF778

431

Q96MU6
CSPTLRIHERTHTGE

ZNF136

291

P52737
RCASTTHELHSPENL

UNC80

911

Q8N2C7
QEHHGAAPTCTSLST

SSH2

881

Q76I76
CDATHVSGPTQHLSR

SYCP2

1271

Q9BX26
ELLGRASPHCHCSTT

ZNRF4

396

Q8WWF5
GHPVSTLSRSSCDLQ

XRN1

1036

Q8IZH2
LSPTTGHCNSGRTRH

NF1

2801

P21359
HQSSISHPLASCAGL

USF3

1246

Q68DE3
QHVTLRCSPISGHTS

TRBV5-7

36

A0A0A0MS05
TRPSNHGKELCVLSH

RNF168

316

Q8IYW5
TPGDHQICLHSNSTR

TMED4

106

Q7Z7H5
PDSSSCLIHERTHTG

ZNF443

291

Q9Y2A4
CPSSLQSHERTHTGE

ZNF443

376

Q9Y2A4
LENPCSESHSLSHTR

ZNF613

546

Q6PF04
GTHTVNSDRLHTPSS

STRADB

321

Q9C0K7
SLLTQETCGHRTPTS

SOX5

71

P35711
DITRHVNSCHQGTPA

ZNF142

1271

P52746
LHSISSHPSGIVSLC

TBC1D19

401

Q8N5T2
SCEITHPSHTSGQIN

TET2

261

Q6N021
DSQPCTHGHLRVTLV

PTPRH

936

Q9HD43
TEGRSVNHLCPTSSD

ZFYVE9

221

O95405