Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	EH domain binding	EPN3 SYNJ1	5.02e-05	2	142	2	GO:1990175
GeneOntologyBiologicalProcess	cell morphogenesis	PLXNA3 SHROOM3 MYOT MAP1B ADAM7 VPS33A MCF2 SIN3A MED1 ITGB2 CNTN6 CCDC88C BMPR1B MEGF8 SEC24B VPS13A CFAP44 TAL1 ATP2B2 CAPRIN1 RASAL1 SEMA3E	1.42e-05	1194	138	22	GO:0000902
Domain	PDZ	SHROOM3 MAST2 MAGI2 MPP4 TJP2 LRRC7 MAST3	8.96e-05	141	139	7	PF00595
Domain	PDZ	SHROOM3 MAST2 MAGI2 MPP4 TJP2 LRRC7 MAST3	1.21e-04	148	139	7	SM00228
Domain	-	SHROOM3 MAST2 MAGI2 MPP4 TJP2 LRRC7 MAST3	1.32e-04	150	139	7	2.30.42.10
Domain	PDZ	SHROOM3 MAST2 MAGI2 MPP4 TJP2 LRRC7 MAST3	1.38e-04	151	139	7	PS50106
Domain	PDZ	SHROOM3 MAST2 MAGI2 MPP4 TJP2 LRRC7 MAST3	1.43e-04	152	139	7	IPR001478
Domain	5-nucleotidase	NT5C1B NT5C1A	1.64e-04	3	139	2	PF06189
Domain	5-nucleotidase	NT5C1B NT5C1A	1.64e-04	3	139	2	IPR010394
Domain	PAH	GON4L SIN3A	1.64e-04	3	139	2	IPR003822
Domain	-	GON4L SIN3A	1.64e-04	3	139	2	1.20.1160.11
Domain	PAH	GON4L SIN3A	1.64e-04	3	139	2	PS51477
Domain	K_chnl_volt-dep_ERG	KCNH7 KCNH6	1.64e-04	3	139	2	IPR003967
Domain	PAH	GON4L SIN3A	1.64e-04	3	139	2	PF02671
Domain	PSI	PLXNA3 ITGB2 MEGF8 SEMA3E	3.17e-04	44	139	4	IPR016201
Domain	DUF1908	MAST2 MAST3	3.27e-04	4	139	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST2 MAST3	3.27e-04	4	139	2	IPR015022
Domain	MAST_pre-PK_dom	MAST2 MAST3	3.27e-04	4	139	2	IPR023142
Domain	-	MAST2 MAST3	3.27e-04	4	139	2	1.20.1480.20
Domain	PSI	PLXNA3 ITGB2 MEGF8 SEMA3E	3.76e-04	46	139	4	SM00423
Domain	DOCK_N	DOCK1 DOCK2	5.42e-04	5	139	2	PF16172
Domain	DOCK_N	DOCK1 DOCK2	5.42e-04	5	139	2	IPR032376
Domain	GUANYLATE_KINASE_2	MAGI2 MPP4 TJP2	6.41e-04	23	139	3	PS50052
Domain	GUANYLATE_KINASE_1	MAGI2 MPP4 TJP2	6.41e-04	23	139	3	PS00856
Domain	Guanylate_kin	MAGI2 MPP4 TJP2	9.25e-04	26	139	3	PF00625
Domain	GK/Ca_channel_bsu	MAGI2 MPP4 TJP2	9.25e-04	26	139	3	IPR008145
Domain	Guanylate_kin-like_dom	MAGI2 MPP4 TJP2	9.25e-04	26	139	3	IPR008144
Domain	GuKc	MAGI2 MPP4 TJP2	9.25e-04	26	139	3	SM00072
Domain	ARM-type_fold	DOCK1 DOCK2 USP34 CAND1 NBEAL1 RICTOR UNC45A TRRAP FHOD1	9.99e-04	339	139	9	IPR016024
Domain	RPEL	PHACTR4 MYOCD	1.13e-03	7	139	2	PS51073
Domain	RPEL	PHACTR4 MYOCD	1.13e-03	7	139	2	SM00707
Domain	RPEL	PHACTR4 MYOCD	1.13e-03	7	139	2	PF02755
Domain	RPEL_repeat	PHACTR4 MYOCD	1.13e-03	7	139	2	IPR004018
Domain	SH3	DOCK1 DOCK2 ARHGAP10 NCKIPSD SH3TC1 MPP4 TJP2	1.18e-03	216	139	7	SM00326
Domain	SH3	DOCK1 DOCK2 ARHGAP10 NCKIPSD SH3TC1 MPP4 TJP2	1.18e-03	216	139	7	PS50002
Domain	SH3_domain	DOCK1 DOCK2 ARHGAP10 NCKIPSD SH3TC1 MPP4 TJP2	1.31e-03	220	139	7	IPR001452
Domain	-	VAPA HYDIN	1.50e-03	8	139	2	2.60.40.360
Domain	Calx_beta	FRAS1 ADGRV1	1.50e-03	8	139	2	SM00237
Domain	Calx_beta	FRAS1 ADGRV1	1.91e-03	9	139	2	IPR003644
Domain	PapD-like	VAPA HYDIN	1.91e-03	9	139	2	IPR008962
Domain	PSI_integrin	ITGB2 MEGF8	1.91e-03	9	139	2	PF17205
Domain	Integin_beta_N	ITGB2 MEGF8	1.91e-03	9	139	2	IPR033760
Domain	Calx-beta	FRAS1 ADGRV1	1.91e-03	9	139	2	PF03160
Domain	PAS_9	KCNH7 KCNH6	2.38e-03	10	139	2	PF13426
Domain	DHR-1_domain	DOCK1 DOCK2	2.89e-03	11	139	2	IPR027007
Domain	DHR_2	DOCK1 DOCK2	2.89e-03	11	139	2	PS51651
Domain	DHR_1	DOCK1 DOCK2	2.89e-03	11	139	2	PS51650
Domain	DHR-2	DOCK1 DOCK2	2.89e-03	11	139	2	PF06920
Domain	DOCK	DOCK1 DOCK2	2.89e-03	11	139	2	IPR026791
Domain	DOCK_C	DOCK1 DOCK2	2.89e-03	11	139	2	IPR010703
Domain	DOCK-C2	DOCK1 DOCK2	2.89e-03	11	139	2	PF14429
Domain	DHR-2	DOCK1 DOCK2	2.89e-03	11	139	2	IPR027357
Domain	FAD-dep_OxRdtase	SQLE PIPOX	3.46e-03	12	139	2	IPR006076
Domain	CRAL_TRIO_2	PRUNE2 MCF2	3.46e-03	12	139	2	PF13716
Domain	DAO	SQLE PIPOX	3.46e-03	12	139	2	PF01266
Domain	EXOIII	REXO5 ERI3	4.72e-03	14	139	2	SM00479
Domain	Exonuclease_RNaseT/DNA_pol3	REXO5 ERI3	4.72e-03	14	139	2	IPR013520
Domain	RNase_T	REXO5 ERI3	4.72e-03	14	139	2	PF00929
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH7 KCNH6	4.72e-03	14	139	2	IPR003938
Domain	Guanylate_kinase_CS	MAGI2 MPP4	6.16e-03	16	139	2	IPR020590
Domain	-	PLXNA3 RASAL1	6.16e-03	16	139	2	1.10.506.10
Pubmed	Network organization of the human autophagy system.	DOCK1 SFXN4 CAND1 MAP1B RPN2 VPS33A PSMC2 UNC45A MAP3K5 GMPS SEC24B ABCD3 TJP2 TAOK1 MAST3	3.87e-10	437	142	15	20562859
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SHROOM3 MAP1B CARMIL1 NCKIPSD TAB2 RICTOR TBC1D22B UNC45A MAST2 CCDC88C MEGF8 DCP1B SYNJ1 MAP4K1 SYNE2 PHACTR4 SEC24B TJP2 PIBF1	2.60e-09	861	142	19	36931259
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	RPL21 DOCK1 VAPA MAP1B RPN2 CARMIL1 PSMC2 MTMR1 TAB2 RICTOR UNC45A GMPS PHACTR4 SEC24B ABCD3 LRRC7	3.71e-08	708	142	16	39231216
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK1 PRUNE2 SHROOM3 TPCN2 CAND1 MAP1B ARHGAP10 CARMIL1 INSR GAS6 ASH1L MSH5 ADGRV1 TRRAP GMPS PTPDC1 BMPR1B CMIP THOP1 SH3TC1 ERI3 LRRC7	1.76e-07	1489	142	22	28611215
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK1 PRUNE2 SHROOM3 SIN3A MAU2 RAD54L2 GRM1 BNIP3L MAP4K1 MDC1 HSH2D SPEN	2.24e-07	430	142	12	35044719
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPN3 PLXNA3 USP34 FRAS1 SHROOM3 MAST2 TRRAP MAP3K5 CCDC88C MEGF8 SYNJ1 SH3TC1 ZNF592 SCN8A ZFYVE26 POFUT1 SPEN RASAL1	6.49e-07	1105	142	18	35748872
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GCFC2 CARMIL1 RICTOR SIN3A MED1 TRRAP ZNF592 MAP4K1 FHOD1 MDC1 PHACTR4 TJP2 TAOK1 SPEN IQCK	7.12e-07	774	142	15	15302935
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DOCK1 DOCK2 SHROOM3 CAND1 RBM45 CDKN2AIP VPS33A PSMC2 UNC45A GMPS FHOD1 HLTF TAOK1	8.59e-07	582	142	13	20467437
Pubmed	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	PRUNE2 CAND1 RPN2 MAGI2	1.23e-06	20	142	4	19668339
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RPN2 ARHGAP10 CDKN2AIP CEP290 PSMC2 MTMR1 TAB2 RICTOR GMPS RFTN1 PTPDC1 SYNE2 SEC24B VPS13A ABCD3 KIRREL1 PIBF1	1.46e-06	1049	142	17	27880917
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	RPL21 VAPA SFXN4 USP34 CAND1 RPN2 ARHGAP10 PSMC2 MTMR1 UNC45A GMPS PTPDC1 THOP1 UBXN7 ABCD3 TJP2	2.56e-06	974	142	16	28675297
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RPL21 VAPA FRAS1 SHROOM3 RPN2 GATC MTMR1 RICTOR UNC45A DARS2 ZNF451 SYNE2 PHACTR4 VPS13A ABCD3 KIRREL1 PIBF1 CAPRIN1 MAST3 HERC5	2.84e-06	1487	142	20	33957083
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MAP1B PSMC2 SIN3A UNC45A MED1 TRRAP SYNJ1 MDC1 PHACTR4 SEC24B TJP2 SPEN	2.88e-06	549	142	12	38280479
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RPL21 USP34 MAP1B RPN2 PSMC2 TRRAP GMPS MDC1 SYNE2 TJP2 SPEN CAPRIN1 HERC5	3.05e-06	653	142	13	22586326
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	VAPA SHROOM3 CAND1 ARHGAP10 CDKN2AIP GON4L RICTOR ERMP1 UNC45A MED1 TRRAP HMG20B JARID2 RFTN1 ZNF592 MDC1 SEC24B ABCD3 HLTF SPEN	3.15e-06	1497	142	20	31527615
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SFMBT1 USP34 SHROOM3 CAND1 INSR RICTOR TBC1D22B PHACTR4 SEC24B VPS13A ABCD3 TJP2 KIRREL1 SPEN	3.95e-06	777	142	14	35844135
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	GCFC2 MAP1B NBEAL1 CEP290 NCKIPSD ASH1L PSMC2 MTMR1 TAB2 MAST2 SYNJ1 ZNF451 TAOK1	5.43e-06	689	142	13	36543142
Pubmed	Human transcription factor protein interaction networks.	VAPA RPN2 PSMC2 GON4L SIN3A RAD54L2 TRRAP HMG20B DCP1B ZNF592 ZNF451 MDC1 SYNE2 UBXN7 SEC24B ABCD3 SPEN TAL1 CAPRIN1	6.08e-06	1429	142	19	35140242
Pubmed	Defining the membrane proteome of NK cells.	RPL21 DOCK2 CAND1 RPN2 CEP290 PSMC2 ERMP1 MED1 ITGB2 DCP1B MAP4K1 FHOD1 ABCD3 HLTF POFUT1 CAPRIN1 ACSL5	6.09e-06	1168	142	17	19946888
Pubmed	Control of developmentally primed erythroid genes by combinatorial co-repressor actions.	SIN3A TRRAP SPEN TAL1	6.72e-06	30	142	4	26593974
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RPL21 CAND1 MAP1B CDKN2AIP CARMIL1 PSMC2 SIN3A UNC45A MED1 GMPS SYNJ1 FHOD1 SEC24B ABCD3 HERC5	7.02e-06	934	142	15	33916271
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DOCK1 KCNH7 GCFC2 NCKIPSD MAP4K1 SEC24B VPS13A SPEN TAL1	9.03e-06	329	142	9	17474147
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	RPL21 SHROOM3 CARMIL1 CEP290 PSMC2 TAB2 UNC45A MAST2 CCDC88C SYNJ1 PHACTR4 SEC24B TJP2 PIBF1	1.13e-05	853	142	14	28718761
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	SIN3A UNC45A MED1 TRRAP DARS2 MDC1 UBXN7 TRMT5 SPEN	1.20e-05	341	142	9	32971831
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SFXN4 FRAS1 MAP1B RPN2 GON4L RICTOR SIN3A RAD54L2 MAST2 ABCD3 HLTF SEMA3E	1.57e-05	650	142	12	38777146
Pubmed	Interaction of voltage-gated sodium channel Nav1.6 (SCN8A) with microtubule-associated protein Map1b.	MAP1B SCN8A	1.66e-05	2	142	2	22474336
Pubmed	Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.	DOCK1 DOCK2	1.66e-05	2	142	2	28467910
Pubmed	The eag family of K+ channels in Drosophila and mammals.	KCNH7 KCNH6	1.66e-05	2	142	2	10414305
Pubmed	Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response.	ITGB2 MAP4K1	1.66e-05	2	142	2	23460610
Pubmed	Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix.	FGF20 FGF9	1.66e-05	2	142	2	19564416
Pubmed	FHOD1 interaction with nesprin-2G mediates TAN line formation and nuclear movement.	FHOD1 SYNE2	1.66e-05	2	142	2	24880667
Pubmed	I-1-deficiency negatively impacts survival in a cardiomyopathy mouse model.	PPP1R1A MYBPC3	1.66e-05	2	142	2	28785686
Pubmed	SPEF2- and HYDIN-Mutant Cilia Lack the Central Pair-associated Protein SPEF2, Aiding Primary Ciliary Dyskinesia Diagnostics.	SPEF2 HYDIN	1.66e-05	2	142	2	31545650
Pubmed	Oxidative Stress Kinase Activation and Impaired Insulin Receptor Signaling Precede Overt Alzheimer's Disease Neuropathology.	INSR MAP3K5	1.66e-05	2	142	2	36189587
Pubmed	The E3 ligase HERC5 promotes antimycobacterial responses in macrophages by ISGylating the phosphatase PTEN.	HERC6 HERC5	1.66e-05	2	142	2	37279284
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	USP34 CAND1 CDKN2AIP SIN3A MAU2 UNC45A MED1 TRRAP GMPS ZNF592 ZNF451 MDC1 UBXN7 HLTF MED26	1.84e-05	1014	142	15	32416067
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EPN3 VAPA SHROOM3 CARMIL1 TBC1D22B UNC45A SYNJ1 PHACTR4 SEC24B TJP2 LRRC7	2.21e-05	565	142	11	25468996
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	PLXNA3 SDK2 TPCN2 ADGRV1 KCNH6	2.52e-05	84	142	5	15203218
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	ARHGAP10 CEP290 PPIL6 CNTN6 DCP1B ZNF451 PHACTR4 UBXN7 HERC6 PIBF1 HYDIN SEMA3E	2.66e-05	686	142	12	29987050
Pubmed	Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3.	MED1 TRRAP MED26	2.92e-05	15	142	3	18418385
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK2 PRUNE2 CEP290 RICTOR CCDC88C RFTN1 KRBA1 CMIP TAOK1 MAST3	3.75e-05	493	142	10	15368895
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 USP34 TAB2 ADGRV1 SYNJ1 SYNE2 POFUT1	4.10e-05	225	142	7	12168954
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	DOCK1 CAND1 MAP1B MAST2 DCP1B ABCD3 MAST3	4.22e-05	226	142	7	25900982
Pubmed	Role of DOCK2 and DOCK180 in fetal thymus colonization.	DOCK1 DOCK2	4.95e-05	3	142	2	19728314
Pubmed	Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice.	FHOD1 MYBPC3	4.95e-05	3	142	2	31008549
Pubmed	Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility.	VAPA VPS13A	4.95e-05	3	142	2	30741634
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH7 KCNH6	4.95e-05	3	142	2	12634931
Pubmed	Developmentally regulated expression of the mouse homologues of the potassium channel encoding genes m-erg1, m-erg2 and m-erg3.	KCNH7 KCNH6	4.95e-05	3	142	2	14643686
Pubmed	mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor.	SIN3A TAL1	4.95e-05	3	142	2	10688671
Pubmed	Potassium Ion Channel Protein (KCNH) Levels in Patients with Fibromyalgia Syndrome.	KCNH7 KCNH6	4.95e-05	3	142	2	35818223
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	FHOD1 SYNE2	4.95e-05	3	142	2	33472039
Pubmed	Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation.	HERC6 HERC5	4.95e-05	3	142	2	37651190
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	FRAS1 MAP1B RPN2 ARHGAP10 UNC45A TRRAP ABCD3 SPEN CAPRIN1	5.06e-05	410	142	9	26949251
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	DOCK1 FRAS1 CEP290 ERMP1 MEGF8	5.83e-05	100	142	5	25807483
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP34 TAB2 RAD54L2 MAST2 UBXN7	6.11e-05	101	142	5	9872452
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 SHROOM3 SDK2 CAND1 ERMP1 ADGRV1 ZNF592 MDC1 UBXN7 SEMA3E	6.74e-05	529	142	10	14621295
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	VAPA SFXN4 CAND1 MAP1B RBM45 RPN2 PSMC2 UNC45A TRRAP GMPS DCP1B ABCD3 HLTF TJP2	6.75e-05	1005	142	14	19615732
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	RPL21 VAPA CAND1 RPN2 CARMIL1 PSMC2 SIN3A UNC45A DARS2 GMPS THOP1 FHOD1 MDC1 SYNE2 ABCD3 HLTF CAPRIN1	6.90e-05	1415	142	17	28515276
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RPL21 VAPA KCNH7 MAP1B VPS33A PSMC2 RICTOR GMPS MAGI2 SYNJ1 ABCD3 TJP2 LRRC7 CAPRIN1 RASAL1	6.91e-05	1139	142	15	36417873
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	RPL21 VPS33A ASH1L MAU2 MED1 TRRAP MAP3K5 ZNF592 MDC1 MED26	7.18e-05	533	142	10	30554943
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	VAPA CAND1 RPN2 VPS33A PSMC2 ERMP1 UNC45A TRRAP DARS2 GMPS THOP1 MDC1 SYNE2 SEC24B POFUT1 CAPRIN1	8.42e-05	1297	142	16	33545068
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	MAP1B CDKN2AIP RAD54L2 MED1 ZNF451 FHOD1 SEC24B MED26 CAPRIN1	9.30e-05	444	142	9	34795231
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	SHROOM3 NCKIPSD RICTOR TBC1D22B MAST2 CCDC88C TJP2 KIRREL1 PIBF1	9.62e-05	446	142	9	24255178
Pubmed	Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics.	NCKIPSD FHOD1	9.88e-05	4	142	2	15095401
Pubmed	Chemokines and integrins independently tune actin flow and substrate friction during intranodal migration of T cells.	DOCK2 ITGB2	9.88e-05	4	142	2	29777221
Pubmed	PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse.	MPP4 ATP2B2	9.88e-05	4	142	2	19233278
Pubmed	Neural crest cell-specific inactivation of Nipbl or Mau2 during mouse development results in a late onset of craniofacial defects.	MAU2 BMPR1B	9.88e-05	4	142	2	24700590
Pubmed	A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.	DOCK1 DOCK2	9.88e-05	4	142	2	15723800
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST2 MAST3	9.88e-05	4	142	2	15951562
Pubmed	Cloning of a mouse cytosolic 5'-nucleotidase-I identifies a new gene related to human autoimmune infertility-related protein.	NT5C1B NT5C1A	9.88e-05	4	142	2	11690631
Pubmed	RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.	RBM45 RICTOR	9.88e-05	4	142	2	38040804
Pubmed	Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy.	KIRREL1 LRRC7	9.88e-05	4	142	2	17968527
Pubmed	Reciprocal inhibition between the transforming growth factor-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) mitogen-activated protein kinase kinase kinases and its suppression by TAK1-binding protein 2 (TAB2), an adapter protein for TAK1.	TAB2 MAP3K5	9.88e-05	4	142	2	22167179
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	USP34 RBM45 SIN3A MAU2 RAD54L2 MED1 ZNF451 MDC1 MAD2L2	1.08e-04	453	142	9	29656893
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	VPS33A MAU2 MED1 GMPS SP140L UBXN7 SCN8A VPS13A TRMT5	1.16e-04	457	142	9	32968282
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CAND1 CEP290 SIN3A TRRAP JARID2 ZNF592 MAD2L2 SPEN HYDIN	1.40e-04	469	142	9	27634302
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	PLXNA3 CDKN2AIP CARMIL1 ASH1L GON4L TBC1D22B ERMP1 MAST2 TXNDC11 CNTN6 GPR68 ZNF451 FHOD1 VPS13A OSCP1	1.41e-04	1215	142	15	15146197
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	RPL21 VAPA SFXN4 RPN2 SQLE TBC1D22B DARS2 GMPS PHACTR4 SEC24B TJP2 KIRREL1 POFUT1	1.51e-04	952	142	13	38569033
Pubmed	The developmental regulator protein Gon4l associates with protein YY1, co-repressor Sin3a, and histone deacetylase 1 and mediates transcriptional repression.	GON4L SIN3A	1.64e-04	5	142	2	21454521
Pubmed	Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.	DOCK1 DOCK2	1.64e-04	5	142	2	12134158
Pubmed	The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.	DOCK1 DOCK2	1.64e-04	5	142	2	24365888
Pubmed	Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins.	DOCK1 DOCK2	1.64e-04	5	142	2	10559471
Pubmed	Myocardin regulates mitochondrial calcium homeostasis and prevents permeability transition.	BNIP3L MYOCD	1.64e-04	5	142	2	29511336
Pubmed	P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL.	SIN3A TAL1	1.64e-04	5	142	2	11118214
Pubmed	An anthropoid-specific segmental duplication on human chromosome 1q22.	ASH1L GON4L	1.64e-04	5	142	2	16545939
Pubmed	The human HERC family of ubiquitin ligases: novel members, genomic organization, expression profiling, and evolutionary aspects.	HERC6 HERC5	1.64e-04	5	142	2	15676274
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	MAP1B TJP2 TAOK1 LRRC7	1.67e-04	67	142	4	29254152
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SFMBT1 RAD54L2 TRRAP ZNF451 MAD2L2	1.67e-04	125	142	5	32891193
Pubmed	The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.	CAND1 SIN3A MED1 GRM1 GMPS MDC1	1.75e-04	199	142	6	36688959
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DOCK1 RPN2 RICTOR UNC45A MED1 CAPRIN1	1.89e-04	202	142	6	33005030
Pubmed	DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination.	SFXN4 UNC45A HLTF	2.03e-04	28	142	3	32937373
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	SFMBT1 CAND1 REXO5 PSMC2 RICTOR SIN3A JARID2 ABCD3 MAD2L2	2.09e-04	495	142	9	27705803
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RPL21 SFMBT1 MAP1B ARHGAP10 MTMR1 SIN3A TRRAP DARS2 HMG20B SH3TC1 SPEN HERC5	2.17e-04	857	142	12	25609649
Pubmed	Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice.	RPL21 PRUNE2 BMPR1B	2.25e-04	29	142	3	21909369
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	VAPA CDKN2AIP UNC45A UBXN7 VPS13A ATP2B2	2.28e-04	209	142	6	26389662
Pubmed	ASK1 negatively regulates the 26 S proteasome.	PSMC2 MAP3K5	2.46e-04	6	142	2	20843792
Pubmed	Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling.	RICTOR POFUT1	2.46e-04	6	142	2	26437242
Pubmed	Atypical recognition consensus of CIN85/SETA/Ruk SH3 domains revealed by target-assisted iterative screening.	SYNJ1 TJP2	2.46e-04	6	142	2	12829691
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	VAPA MAP1B NCKIPSD PSMC2 MTMR1 TRRAP SYNJ1 LRRC7 ATP2B2 RASAL1	2.47e-04	621	142	10	22794259
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	VAPA SDK2 CDKN2AIP PSMC2 TAB2 TBC1D22B BOD1 SYNJ1 SYNE2 SEC24B KIRREL1 POFUT1 CAPRIN1	2.60e-04	1007	142	13	34597346
Interaction	YWHAH interactions	VAPA SHROOM3 CARMIL1 CEP290 NCKIPSD PSMC2 TAB2 RICTOR TBC1D22B ERMP1 UNC45A MED1 MAST2 MAP3K5 CCDC88C PTPDC1 MEGF8 DCP1B SYNJ1 SYNE2 PHACTR4 SEC24B TJP2 TAOK1 PIBF1 MAST3	3.71e-08	1102	140	26	int:YWHAH
Interaction	KCNA3 interactions	RPL21 DOCK1 VAPA MAP1B RPN2 CARMIL1 SPEF2 PSMC2 MTMR1 TAB2 RICTOR UNC45A GMPS CCDC88C PHACTR4 SEC24B VPS13A ABCD3 LRRC7 SPEN	2.55e-06	871	140	20	int:KCNA3
Interaction	GGH interactions	PLXNA3 FRAS1 RPN2 CDKN2AIP INSR GAS6 ADGRV1 MEGF8 ART5 ATP2B2	7.87e-06	243	140	10	int:GGH
Interaction	BICD1 interactions	RPL21 SHROOM3 CARMIL1 NCKIPSD TAB2 CCDC88C SYNJ1 SEC24B TJP2 PIBF1	1.01e-05	250	140	10	int:BICD1
Interaction	IRF2BP2 interactions	RBM45 RPN2 SIN3A TRRAP GMPS SPEN TAL1	1.18e-05	110	140	7	int:IRF2BP2
Interaction	USP9X interactions	USP34 CAND1 MAP1B RBM45 RPN2 CEP290 MTMR1 RICTOR ITGB2 MAP3K5 PTPDC1 UBXN7	3.96e-05	422	140	12	int:USP9X
GeneFamily	PDZ domain containing	SHROOM3 MAST2 MAGI2 MPP4 TJP2 LRRC7 MAST3	1.00e-05	152	89	7	1220
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI2 MPP4 TJP2	2.76e-04	26	89	3	904
GeneFamily	CD molecules\|5'-nucleotidases	NT5C1B NT5C1A	4.95e-04	7	89	2	1042
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SDK2 MYOT CNTN6 KIRREL1 MYBPC3	1.20e-03	161	89	5	593
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MAP1B GRM1 PPP1R1A PHACTR4 HYDIN	2.00e-03	181	89	5	694
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK1 SFMBT1 USP34 CAND1 MAP1B TAB2 MED1 MAST2 TRRAP GMPS JARID2 RFTN1 ZNF451 SYNE2 UBXN7 SEC24B VPS13A HLTF TJP2 PIBF1 SPEN	7.65e-09	856	142	21	M4500
Coexpression	GSE6259_DEC205_POS_DC_VS_CD8_TCELL_DN	CHST5 CARMIL1 GATC RAD54L2 JARID2 KRBA1 SYNJ1 SYNE2	2.04e-06	154	142	8	M6776
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	DOCK2 TPCN2 GON4L MAU2 RAD54L2 TRRAP ITGB2 JARID2 KRBA1 CMIP MAP4K1 MDC1 PHACTR4 HSH2D ZFYVE26 SPEN MAST3	8.57e-06	905	142	17	M40865
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	PLXNA3 CAND1 ARHGAP10 VPS33A INSR RICTOR TBC1D22B MAU2 RAD54L2 MED1 CR1L TXNDC11 KRBA1 UBXN7 HLTF ACSL5 MAST3	8.88e-07	629	140	17	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	DOCK1 VAPA SFMBT1 MAP1B VPS33A INSR ASH1L ZNF451 UBXN7 TAOK1 MYOCD CAPRIN1	2.00e-06	330	140	12	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000	DOCK1 VAPA SFMBT1 NBEAL1 INSR MTMR1 MAU2 ZNF451 VPS13A TAOK1 CAPRIN1	4.00e-05	375	140	11	gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	DOCK1 SFMBT1 MAP1B VPS33A INSR MED1 UBXN7 SEC24B TAOK1 MYOCD CAPRIN1	5.07e-05	385	140	11	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500	DOCK1 VAPA SFMBT1 CAND1 MAP1B INSR MTMR1 CAPRIN1	5.76e-05	201	140	8	gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500	DOCK1 VAPA SFMBT1 CAND1 MAP1B INSR MTMR1 SCN8A HLTF FGF9 CAPRIN1	7.46e-05	402	140	11	gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	SHROOM3 SDK2 MAP1B SQLE CEP290 INSR MTMR1 ADGRV1 CNTN6 CCDC88C JARID2 PTPDC1 SYNE2 TJP2 TAOK1 PIBF1 ATP2B2 IQCK	8.73e-05	986	140	18	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_200	MAP1B INSR UBXN7 TAOK1 MYOCD	1.38e-04	75	140	5	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	DOCK1 SFMBT1 MAP1B VPS33A INSR UBXN7 VPS13A TAOK1 MYOCD CAPRIN1	1.73e-04	369	140	10	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000	DOCK1 VAPA SFMBT1 NBEAL1 INSR MTMR1 MAU2 BMPR1B ZNF451 SCN8A VPS13A HLTF FGF9 TAOK1 CAPRIN1	1.85e-04	774	140	15	gudmap_developingKidney_e15.5_cortic collect duct_1000
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	FRAS1 SHROOM3 INSR MAGI2 BMPR1B SYNE2 SEMA3E	1.63e-06	178	141	7	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	ASH1L SP140L SYNE2 PHACTR4 HSH2D TAOK1 HERC5	1.96e-06	183	141	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP10 GRM1 MAP3K5 CCDC88C RFTN1 HYDIN MAST3	1.96e-06	183	141	7	1645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP10 GRM1 MAP3K5 CCDC88C RFTN1 HYDIN MAST3	2.03e-06	184	141	7	34e316ad8e7b8667cd8ad61397281802a252744f
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 SHROOM3 INSR ADGRV1 MAGI2 BMPR1B SEMA3E	2.26e-06	187	141	7	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 SHROOM3 SDK2 ADGRV1 CNTN6 MAP3K5 SYNE2	2.26e-06	187	141	7	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 SHROOM3 INSR ADGRV1 MAGI2 BMPR1B SEMA3E	2.51e-06	190	141	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SHROOM3 INSR ASH1L MAGI2 CMIP SYNE2	2.69e-06	192	141	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 CAND1 NBEAL1 ADGRV1 MED1 TAOK1 CAPRIN1	2.79e-06	193	141	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	PBMC-Mild\|PBMC / Compartment, Disease Groups and Clusters	RICTOR ITGB2 TXNDC11 JARID2 HSH2D HERC6 HERC5	2.89e-06	194	141	7	d1366b169d14011194e61d16b6b0953349febc78
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 SHROOM3 INSR ADGRV1 CNTN6 BMPR1B SEMA3E	3.30e-06	198	141	7	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	FRAS1 NBEAL1 CARMIL1 CNTN6 FHOD1 SYNE2 SEMA3E	3.30e-06	198	141	7	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 SHROOM3 ADGRV1 CNTN6 BMPR1B SYNE2 SEMA3E	3.30e-06	198	141	7	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Macroglial-Astrocytes-GFAP---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHROOM3 CARMIL1 TAB2 ADGRV1 BMPR1B TJP2 LIX1	3.53e-06	200	141	7	88d66550781a3c9102ff7455f5cff6fb072943cd
ToppCell	Macroglial-Astrocytes-GFAP-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHROOM3 CARMIL1 TAB2 ADGRV1 BMPR1B TJP2 LIX1	3.53e-06	200	141	7	d6a059b0ef763c281c60b1ac76da6079ea822f80
ToppCell	Macroglial-Astrocytes-GFAP--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHROOM3 CARMIL1 TAB2 ADGRV1 BMPR1B TJP2 LIX1	3.53e-06	200	141	7	16269fa4adb28fc6ed032bbdba8781237dd0d249
ToppCell	Macroglial-Astrocytes-GFAP----L1-2\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHROOM3 CARMIL1 TAB2 ADGRV1 BMPR1B TJP2 LIX1	3.53e-06	200	141	7	c6f43bbbd5df5f2c19ae385f1a6b6a330abede2f
ToppCell	Macroglial-Astrocytes-GFAP\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHROOM3 CARMIL1 TAB2 ADGRV1 BMPR1B TJP2 LIX1	3.53e-06	200	141	7	79634b1086934412ae92f259ab43554ce545008f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SDK2 ARHGAP10 CNTN6 LIX1 RASAL1 SEMA3E	3.69e-06	130	141	6	05d5a73acf1d7f75a79876b1a06d27c74a89b8a4
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	TAB2 BMPR1B MEGF8 FGF20 SPEN TAL1	1.30e-05	162	141	6	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 ADAM7 ADGRV1 CNTN6 LRRC7 HYDIN	1.30e-05	162	141	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	EPN3 PCDHB4 CNTN6 PPP1R1A BMPR1B POFUT1	1.40e-05	164	141	6	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 FRAS1 MAGI2 SYNE2 HYDIN RASAL1	1.60e-05	168	141	6	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL21 FRAS1 ADGRV1 CNTN6 ATP2B2 HYDIN	1.66e-05	169	141	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARHGAP10 NCKIPSD PSMC2 DCP1B SYNE2 HERC5	1.83e-05	172	141	6	eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP10 GRM1 MAP3K5 CCDC88C RFTN1 MAST3	2.08e-05	176	141	6	07abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 SHROOM3 CARMIL1 CNTN6 MAP3K5 FHOD1	2.15e-05	177	141	6	9af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ARHGAP10 GRM1 MAP3K5 CCDC88C RFTN1 MAST3	2.22e-05	178	141	6	5d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 KCNH6 BNIP3L SYNE2 LRRC7 G6PC1	2.36e-05	180	141	6	f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 SHROOM3 ADGRV1 MAGI2 BMPR1B SEMA3E	2.36e-05	180	141	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	COVID_non-vent-Lymphocytic-T_cell-Gamma_Delta_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CHST5 SDK2 MCF2 ART5 G6PC1	2.42e-05	108	141	5	04bfb90634b691020f246a8afbebd3bf944d1e0e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 ERMP1 ADGRV1 MAGI2 LIX1	2.44e-05	181	141	6	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 ERMP1 ADGRV1 MAGI2 LIX1	2.52e-05	182	141	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 FRAS1 MAP1B ARHGAP10 MYOCD LRRC7	2.59e-05	183	141	6	61a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 SHROOM3 ADGRV1 TXNDC11 CNTN6 SEMA3E	2.93e-05	187	141	6	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	CFAP107 MAP1B SPEF2 PPIL6 CFAP44 HYDIN	2.93e-05	187	141	6	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	critical-Myeloid-Monocyte-derived_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGAP10 PHACTR4 HSH2D HERC6 LIX1 HERC5	2.93e-05	187	141	6	72e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 ERMP1 ADGRV1 MAGI2 LIX1	2.93e-05	187	141	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	2.93e-05	187	141	6	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 ASH1L RICTOR SYNE2 TAOK1 SPEN	3.02e-05	188	141	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	tumor_Lung-Epithelial_cells-tS3\|tumor_Lung / Location, Cell class and cell subclass	CFAP107 MAP1B SPEF2 PPIL6 OSCP1 HYDIN	3.02e-05	188	141	6	26326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	MAP1B SPEF2 CEP290 PPIL6 CFAP44 HYDIN	3.02e-05	188	141	6	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ERMP1 ADGRV1 MAGI2 SYNE2 HYDIN	3.02e-05	188	141	6	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 FRAS1 MAP1B CMIP MYOCD LRRC7	3.02e-05	188	141	6	879de94924de978478696fc7838e05a4d795b905
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK1 FRAS1 MAP3K5 KIRREL1 FGF9 HYDIN	3.02e-05	188	141	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 SHROOM3 NBEAL1 ARHGAP10 CARMIL1 MYOCD	3.11e-05	189	141	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ARHGAP10 MAP3K5 KCNH6 BNIP3L SYNE2	3.11e-05	189	141	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 GAS6 ERMP1 ADGRV1 LIX1	3.20e-05	190	141	6	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPL21 CHST5 CARMIL1 BCDIN3D BMPR1B SEMA3E	3.20e-05	190	141	6	7179f980f895d3e5b839b5ae26b5c991787bfe3a
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 NBEAL1 ASH1L TAB2 CMIP SYNE2	3.30e-05	191	141	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	Calu_3-infected-SARSCoV2\|infected / Cell line, Condition and Strain	SP140L SYNE2 PHACTR4 HSH2D HERC6 HERC5	3.30e-05	191	141	6	2da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 NBEAL1 ASH1L TAB2 CMIP SYNE2	3.30e-05	191	141	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 NBEAL1 ASH1L TAB2 CMIP SYNE2	3.30e-05	191	141	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	multiciliated\|World / shred by cell class for turbinate	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.39e-05	192	141	6	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	MAP1B SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.49e-05	193	141	6	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SHROOM3 SPEF2 SQLE PPIL6 PLA2G4F HYDIN	3.49e-05	193	141	6	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.49e-05	193	141	6	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	Hippocampus-Neuronal\|Hippocampus / BrainAtlas - Mouse McCarroll V32	USP34 MAP1B SYNJ1 SCN8A TAOK1 ATP2B2	3.60e-05	194	141	6	8aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 SHROOM3 ADGRV1 BMPR1B SYNE2 SEMA3E	3.70e-05	195	141	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.70e-05	195	141	6	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.81e-05	196	141	6	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.81e-05	196	141	6	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.81e-05	196	141	6	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.81e-05	196	141	6	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	Severe_COVID-19-Epithelial-Ciliated\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.81e-05	196	141	6	1cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	3.81e-05	196	141	6	69f5081e06d84ec1d9695762df801a9d0df1984b
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	DOCK2 USP34 NBEAL1 INSR ITGB2 UBXN7	4.03e-05	198	141	6	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	4.03e-05	198	141	6	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	DOCK2 USP34 NBEAL1 INSR ITGB2 UBXN7	4.03e-05	198	141	6	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	COVID-19_Mild-PLT_4\|COVID-19_Mild / Disease Group and Platelet Clusters	VAPA CDKN2AIP GMPS BNIP3L ZNF451 HLTF	4.03e-05	198	141	6	3d8c33dba759df0974aeb2b9a6b5167ae7a18e1f
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FRAS1 NBEAL1 CNTN6 FHOD1 SYNE2 SEMA3E	4.03e-05	198	141	6	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRUNE2 MYOT MAP1B PPP1R1A MYOCD LIX1	4.03e-05	198	141	6	e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	DOCK2 USP34 NBEAL1 INSR ITGB2 UBXN7	4.03e-05	198	141	6	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 ASH1L RICTOR ZNF451 SYNE2 VPS13A	4.14e-05	199	141	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	EPN3 FRAS1 NBEAL1 CNTN6 FHOD1 SYNE2	4.14e-05	199	141	6	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	ASH1L SP140L SYNE2 HSH2D HERC6 HERC5	4.14e-05	199	141	6	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	USP34 MAP1B GMPS CMIP SYNJ1 TAOK1	4.14e-05	199	141	6	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	(10)_Ciliated\|World / shred by cell type by condition	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	4.26e-05	200	141	6	1b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCell	Biopsy_Control_(H.)-Epithelial-Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	4.26e-05	200	141	6	9ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SHROOM3 ARHGAP10 MAP3K5 CCDC88C RFTN1 BMPR1B	4.26e-05	200	141	6	9c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCell	Biopsy_Other_PF-Epithelial-Differentiating_Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	4.26e-05	200	141	6	f7b4581d958afbd68f9045af619aaca0ab463439
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FRAS1 NBEAL1 CNTN6 FHOD1 SYNE2 SEMA3E	4.26e-05	200	141	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	SPEF2 NCKIPSD SH3TC1 FHOD1 ZFYVE26 MAST3	4.26e-05	200	141	6	e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	4.26e-05	200	141	6	7cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SHROOM3 ARHGAP10 MAP3K5 CCDC88C RFTN1 BMPR1B	4.26e-05	200	141	6	8821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ARHGAP10 MAP3K5 CCDC88C RFTN1 HYDIN MAST3	4.26e-05	200	141	6	0f23e72649a274043bf23e0952a9b5707c516acf
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SHROOM3 ARHGAP10 MAP3K5 CCDC88C RFTN1 BMPR1B	4.26e-05	200	141	6	96b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP107 SPEF2 PPIL6 OSCP1 CFAP44 HYDIN	4.26e-05	200	141	6	8441e289377215a6877640946fe3f6de1f456502
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SHROOM3 ARHGAP10 MAP3K5 CCDC88C RFTN1 BMPR1B	4.26e-05	200	141	6	ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	ASH1L ERMP1 GPR68 PLA2G4F SPEN	4.35e-05	122	141	5	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-immature_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 TPCN2 INSR TRMT5 ART5	6.33e-05	132	141	5	9936078c328b1e1d59f9dfdd69d36926a0cdaf0d
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 CNTN6 LRRC7 HYDIN	9.86e-05	145	141	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CARMIL1 GAS6 TXNDC11 CCDC88C HSH2D	1.48e-04	158	141	5	6b51e5ee08e23924f5edbaf0a845a9232fb7ff7a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-Plasma_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CARMIL1 GAS6 TXNDC11 CCDC88C HSH2D	1.48e-04	158	141	5	8dd83a2a4c2ec9cdc3a03df8b51ee22bee1c2888
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 CR1L CCDC88C BMPR1B SH3TC1	1.48e-04	158	141	5	debebc8534a80e5500051f6fd352dc201585968d
ToppCell	facs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP10 RICTOR KCNH6 SH3TC1 IQCK	1.56e-04	160	141	5	b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 TPCN2 NXPE4 FHOD1 PLA2G4F	1.71e-04	163	141	5	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM45 MTMR1 MEGF8 ZNF451 POFUT1	1.71e-04	163	141	5	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 TPCN2 NXPE4 FHOD1 PLA2G4F	1.71e-04	163	141	5	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 TXNDC11 CCDC88C HSH2D MYBPC3	1.91e-04	167	141	5	0130743084dbcb20e10f96715d30961122150cbf
Disease	Cerebral ventriculomegaly	SIN3A CCDC88C HYDIN	3.53e-06	7	139	3	C1531647
Disease	Hydrocephalus Ex-Vacuo	SIN3A CCDC88C HYDIN	3.53e-06	7	139	3	C0270720
Disease	Communicating Hydrocephalus	SIN3A CCDC88C HYDIN	3.53e-06	7	139	3	C0009451
Disease	Fetal Cerebral Ventriculomegaly	SIN3A CCDC88C HYDIN	3.53e-06	7	139	3	C2936718
Disease	Post-Traumatic Hydrocephalus	SIN3A CCDC88C HYDIN	3.53e-06	7	139	3	C0477432
Disease	Obstructive Hydrocephalus	SIN3A CCDC88C HYDIN	3.53e-06	7	139	3	C0549423
Disease	Congenital Hydrocephalus	SIN3A CCDC88C HYDIN	5.63e-06	8	139	3	C0020256
Disease	Aqueductal Stenosis	SIN3A CCDC88C HYDIN	5.63e-06	8	139	3	C2936786
Disease	Hydrocephalus	SIN3A CCDC88C HYDIN	8.42e-06	9	139	3	C0020255
Disease	urate measurement	SFMBT1 USP34 TPCN2 CARMIL1 INSR ASH1L GON4L SIN3A ADGRV1 PTPDC1 CMIP HERC6 G6PC1 MAST3	8.86e-05	895	139	14	EFO_0004531
Disease	hippocampal atrophy	PRUNE2 GCFC2 RPN2 MAGI2	1.43e-04	56	139	4	EFO_0005039
Disease	gestational diabetes (biomarker_via_orthology)	INSR BNIP3L	2.18e-04	5	139	2	DOID:11714 (biomarker_via_orthology)
Disease	Cardiomyopathies, Primary	MYOT MAP3K5 PPP1R1A MYBPC3	3.22e-04	69	139	4	C0033141
Disease	Myocardial Diseases, Secondary	MYOT MAP3K5 PPP1R1A MYBPC3	3.22e-04	69	139	4	C0036529
Disease	bipolar disorder, anorexia nervosa	MAU2 ZNF592	3.26e-04	6	139	2	MONDO_0004985, MONDO_0005351
Disease	Cardiomyopathies	MYOT MAP3K5 PPP1R1A MYOCD MYBPC3	3.85e-04	130	139	5	C0878544
Disease	hair color	FRAS1 TPCN2 ERMP1 MSH5 ADGRV1 SYNE2 PADI3	7.04e-04	311	139	7	EFO_0003924
Disease	Paroxysmal atrial fibrillation	USP34 MYOT ARHGAP10 SYNE2 MYOCD	8.82e-04	156	139	5	C0235480
Disease	familial atrial fibrillation	USP34 MYOT ARHGAP10 SYNE2 MYOCD	8.82e-04	156	139	5	C3468561
Disease	Persistent atrial fibrillation	USP34 MYOT ARHGAP10 SYNE2 MYOCD	8.82e-04	156	139	5	C2585653
Disease	response to carboplatin, response to antineoplastic agent	SPEF2 CMIP	9.67e-04	10	139	2	GO_0097327, GO_0097328
Disease	long QT syndrome (implicated_via_orthology)	KCNH7 KCNH6	9.67e-04	10	139	2	DOID:2843 (implicated_via_orthology)
Disease	Atrial Fibrillation	USP34 MYOT ARHGAP10 SYNE2 MYOCD	9.87e-04	160	139	5	C0004238
Disease	prostate carcinoma	DOCK2 ZWILCH SHROOM3 TPCN2 MAST2 CNTN6 CCDC88C BOD1 SYNE2 MYOCD CFAP44 SPEN	1.07e-03	891	139	12	EFO_0001663
Disease	autosomal dominant nonsyndromic deafness (is_implicated_in)	MAP1B ATP2B2	1.18e-03	11	139	2	DOID:0050564 (is_implicated_in)
Disease	level of Ceramide (d40:1) in blood serum	SYNE2 G6PC1	1.18e-03	11	139	2	OBA_2045185
Disease	triglyceride measurement, alcohol drinking	INSR GAS6 CMIP MYBPC3	1.26e-03	99	139	4	EFO_0004329, EFO_0004530
Disease	Gastric Adenocarcinoma	INSR TRRAP BMPR1B	1.26e-03	45	139	3	C0278701
Disease	triglyceride measurement, alcohol consumption measurement	INSR GAS6 CMIP MYBPC3	1.35e-03	101	139	4	EFO_0004530, EFO_0007878
Disease	chronic kidney disease (implicated_via_orthology)	SHROOM3 INSR	1.41e-03	12	139	2	DOID:784 (implicated_via_orthology)
Disease	cardiotoxicity, response to anthracycline-based chemotherapy	PRUNE2 MPP4	1.93e-03	14	139	2	EFO_0005257, EFO_1001482
Disease	unipolar depression, anxiety	CDKN2AIP LRRC7	1.93e-03	14	139	2	EFO_0003761, EFO_0005230
Disease	free androgen index	ARHGAP10 INSR SIN3A CMIP THOP1 FGF9 ATP2B2	2.03e-03	374	139	7	EFO_0007005
Disease	pulse pressure measurement	USP34 SHROOM3 MAP1B NBEAL1 CARMIL1 INSR MSH5 CR1L MAST2 BMPR1B MEGF8 PHACTR4 FGF9 HYDIN MYBPC3	2.41e-03	1392	139	15	EFO_0005763
Disease	glycoprotein measurement	ARHGAP10 ADGRV1 CMIP HYDIN	2.46e-03	119	139	4	EFO_0004555
Disease	pursuit maintenance gain measurement	SDK2 CARMIL1 MAGI2 CMIP	2.78e-03	123	139	4	EFO_0008433
Disease	level of Sphingomyelin (d32:1) in blood serum	ERMP1 SYNE2	2.86e-03	17	139	2	OBA_2045173
Disease	angina pectoris	NBEAL1 CARMIL1 BMPR1B MDC1	2.94e-03	125	139	4	EFO_0003913
Disease	cutaneous melanoma, hair color	TPCN2 ADGRV1 SYNE2	3.16e-03	62	139	3	EFO_0000389, EFO_0003924
Disease	white matter integrity	NBEAL1 CDKN2AIP ADAM7 CCDC88C	3.39e-03	130	139	4	EFO_0004641
Disease	fat body mass	PRUNE2 USP34 KCNH7 PPP1R1A MAST3	3.72e-03	217	139	5	EFO_0005409
Disease	glycine measurement	INSR ERMP1 ADGRV1 MAST3	4.08e-03	137	139	4	EFO_0009767
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	SHROOM3 INSR GAS6 CMIP SYNE2	4.26e-03	224	139	5	EFO_0004530, EFO_0008317
Disease	waist circumference	GRM1 BCDIN3D PPP1R1A SYNE2 PIBF1 PADI3 IQCK	4.32e-03	429	139	7	EFO_0004342
Disease	coronary atherosclerosis measurement, traffic air pollution measurement	DOCK1 CAPRIN1	4.36e-03	21	139	2	EFO_0007908, EFO_0007938
Disease	obsolete_red blood cell distribution width	CARMIL1 INSR GAS6 MAU2 CR1L TXNDC11 BNIP3L SYNE2 VPS13A HSH2D TAOK1 PIBF1 TAL1 MAST3	4.61e-03	1347	139	14	EFO_0005192

Protein segments in the cluster

Peptide	Gene	Start	Entry
HEQILVLDPPTDLKF	VAPA	11	Q9P0L0
SPILVKIRPHIFFDD	NT5C1B	571	Q96P26
DKPQIHPQEIIEFPI	ERI3	156	O43414
PPSFVDHDFLKRRLP	ASH1L	766	Q9NR48
PLLEKIRPHIFFDDQ	NT5C1A	316	Q9BXI3
EPILPEIHFLNKPAS	ADAM7	726	Q9H2U9
LFRAKQTIETHPIPE	BCDIN3D	261	Q7Z5W3
EKPVPPASHRDEDLQ	EPN3	226	Q9H201
HQKFTHFLPRPVDPD	FGF9	181	P31371
PIILHAFPDKIPEFN	ADGRV1	1186	Q8WXG9
LLQPIPFPKEALAHE	CMIP	476	Q8IY22
LLHFVEKEPAPQVSL	RAD54L2	906	Q9Y4B4
LHPTLPPLKNRDFVD	BMPR1B	106	O00238
PSHATEQRPQKEPID	CAPRIN1	451	Q14444
IPQIHPEEVPEKRFQ	CFAP44	1256	Q96MT7
EVSPRNPPHFRLISK	ERMP1	766	Q7Z2K6
PEFRIEDSQPHIPLI	ATP2B2	1171	Q01814
FKNVERDPHFILDVP	MTMR1	136	Q13613
HPPRLSAEEAVQKPT	NBEAL1	2281	Q6ZS30
PAILTPKLFDLRDQH	RASAL1	476	O95294
IVFNPHPLPLDVLED	RBM45	396	Q8IUH3
SLDHPTDQKLIPEFI	RFTN1	131	Q14699
SIPFVEERLKQHPRP	IQCK	191	Q8N0W5
LIENHEKIFRTPPDT	ARHGAP10	566	A1A4S6
LHQTLDFDEFIPPLP	FAM189A1	231	O60320
LKELPEAQDRHPSPS	KRBA1	276	A5PL33
APKELFFELRRPPQH	FRAS1	1626	Q86XX4
HPANPAEKIIRVLFP	MAP1B	476	P46821
EHRPVEKFVFEITQP	MAD2L2	91	Q9UI95
LPFPSISKQHAEIEI	MDC1	66	Q14676
RQDVKPDIRQPPFTD	MAGI2	1076	Q86UL8
NISLPKLDEQEPFPH	GATC	121	O43716
EVKAEKRIPPPFQHN	LRRC7	1041	Q96NW7
LRVKEFIRFHQIPNP	KCNH7	681	Q9NS40
RVKEFIRFHQIPNPL	KCNH6	531	Q9H252
DEESRPVNLPPALKH	CDKN2AIP	561	Q9NXV6
FSLAPPKEERLAPLH	CCDC88C	1886	Q9P219
FTISDHPQPIDPLLK	CAND1	991	Q86VP6
IEAHPVLKELDTPPN	PLXNA3	1311	P51805
HETILQKKDEFPPSP	HERC6	656	Q8IVU3
FLEEISPHLKEPRPR	MEGF8	1771	Q7Z7M0
HDTIAQKDFEPLLPP	MPP4	126	Q96JB8
IVNLLKDDLHPSFPE	INSR	1286	P06213
PQSPEPDLHKEALVR	PTPDC1	436	A2A3K4
VRDFLHAQKVQPPVE	PADI3	446	Q9ULW8
HPSKFEDPILVPLQE	PPIL6	51	Q8IXY8
KAEDPRSPIVLHFPL	PLA2G4F	751	Q68DD2
PLTQKEPVRADSPVH	MED26	436	O95402
KRILDQNFGEPHIPS	PHACTR4	396	Q8IZ21
EQTIHNPLEVVPSKF	RICTOR	1556	Q6R327
VTFHQQKPIEPRREL	HSH2D	106	Q96JZ2
QGIIPPLKRPAEFHE	MYOCD	36	Q8IZQ8
LPHRDPALVFKDLNV	LIX1	16	Q8N485
DNLLKRLPFHSPPQE	HERC5	471	Q9UII4
NDHSPIFPEREVLLK	PCDHB4	126	Q9Y5E5
VLPFVNTHPDKLRNP	ITGB2	176	P05107
SLAIFEEPVHPLPQE	CCNYL3	46	P0C7X3
YEEPRRHSPPIEKQL	DCP1B	276	Q8IZD4
PELQEPKVLTLAPFH	HYDIN	4461	Q4G0P3
TPLHFDRDPLQKQPS	GMPS	616	P49915
LDLPPKFHRPVSEQI	DOCK1	1411	Q14185
VQPVLDEHPRFKNKP	DOCK2	1411	Q92608
DEHPRFKNKPVPDQI	DOCK2	1416	Q92608
EPDDHEKRIPFTLRP	GCFC2	181	P16383
PTPVPTNKHFIRLAE	CEP290	1611	O15078
LHVFDSLKPPSQVEL	G6PC1	306	P35575
IPFHEKDLVQPINPR	GAS6	426	Q14393
VVDPKLNHIFRPQIE	BOD1	136	Q96IK1
PPPDVLHAERTQRDK	CR1L	291	Q2VPA4
RKEYIPFPDHRPDQI	CFAP107	51	Q8N1D5
PQIPDHLKEPFLEAT	SQLE	366	Q14534
SPQEKPLRTLFHQPE	GON4L	206	Q3T8J9
ANEIKPPQFVDIHLE	GON4L	351	Q3T8J9
SRPENIPPKEFHFRH	BNIP3L	146	O60238
EQVKAIFLHPEPFSI	ACSL5	636	Q9ULC5
PIFTQEPHDVIFPLD	CNTN6	26	Q9UQ52
DKHVRPIQFVVPTPE	MCF2	426	P10911
EKLHQLPFQPTADEL	MAST2	256	Q6P0Q8
ERLHQLPFQPTPDEL	MAST3	111	O60307
LVNVHFAPRIVVDPK	KIRREL1	301	Q96J84
IHIEDPPFPSLRQEK	CARMIL1	951	Q5VZK9
EPAEAIETPLLPHQK	HLTF	231	Q14527
PPVHVIKAALLNFDE	FHOD1	711	Q9Y613
FSVHHQPPAEKVPER	GRM1	51	Q13255
PHKRPEVQNSTVEFI	SEC24B	651	O95487
EPPQFVKEPERHITA	SDK2	306	Q58EX2
PFKPPQRIEARTHLQ	MAU2	56	Q9Y6X3
PPEKPKHQTEDDFQR	MED1	696	Q15648
EIPVLRPSAKEFHDP	JARID2	556	Q92833
PAQFPVLEEHRPLQK	POFUT1	196	Q9H488
EEPELLTKLHPAFQT	GPR68	336	Q15743
EHREPKRPEIIFLPS	MSH5	121	O43196
EQIRTRHPDLPFPEI	HMG20B	86	Q9P0W2
LKSQPIEIPELPVFH	MAP3K5	1286	Q99683
IELAELQPPLFDVHP	MAP4K1	206	Q92918
KFTHFLPRPVDPERV	FGF20	186	Q9NP95
LHPERFVNLGIEPPK	PSMC2	196	P35998
VDFSDVKPQHRVPRP	SPATA48	131	A4D263
VVDFPLFLPKEENPR	DARS2	481	Q6PI48
PLEPLPFNRQEHLIE	SPEF2	1596	Q9C093
PENHEDPPLKRQRTA	TRMT5	481	Q32P41
AQHPPLDPRLTKNFI	TBC1D22B	26	Q9NU19
RELPPEIPSHSANVK	PRUNE2	1246	Q8WUY3
VHPDSSNLIPKLFRP	SFXN4	96	Q6P4A7
TFENKDENHLPLVPP	SYNE2	446	Q8WXH0
QVLHDLRQKFPEVPE	TAB2	11	Q9NYJ8
HKLDPPPFSLIVETR	SYNJ1	11	O43426
IEKLDQQIPPRPFTH	NXPE4	76	Q6UWF7
AFAELRKLIPTHPPD	TAL1	206	P17542
TSPELREHLAQKPVF	SIN3A	1111	Q96ST3
PFIEEQLHTVLEKSP	SHROOM3	426	Q8TF72
PQDRPTSEELLKHIF	TAOK1	266	Q7L7X3
VHLKQPEEALPFLER	SH3TC1	676	Q8TE82
PRPKDVLLVTFNHLD	OSCP1	116	Q8WVF1
HKDETVDFQAPLLPV	SP140L	291	Q9H930
RGDDPVRIFKHEPQP	NCKIPSD	596	Q9NZQ3
ADNIIKFDHVPLATP	ABCD3	436	P28288
HLFERELGVKPSQQP	ACTRT1	91	Q8TDG2
HVRIAEAATLKPPPF	CHST5	271	Q9GZS9
HAGRLDEQLPKQIPF	ZNF451	961	Q9Y4E5
EQHIFQLPVRPTAVK	ZWILCH	506	Q9H900
VQHEESIRKPSPEPR	TJP2	956	Q9UDY2
IVEFFRPPKEVHLAQ	VPS13A	601	Q96RL7
LVLPHTEFQPAPKQD	SPEN	3471	Q96T58
IQHLFREPEKRPPTV	RPN2	526	P04844
PFEQEALQTLKLDHP	REXO5	701	Q96IC2
PVLEALAKFPVPELH	ZNF592	181	Q92610
PKEHEDNIFTPKPTL	PIBF1	726	Q8WXW3
VQLKRQPAPPREAHF	RPL21	126	P46778
FADALEHPLRVPKPN	SCN8A	1811	Q9UQD0
LAAQREVHPKQPEPS	TXNDC11	941	Q6PKC3
PHTEEEVRAPIPQKQ	UBXN7	71	O94888
DVFLLPTRDHKNPVI	SEMA3E	311	O15041
PQRCFPPLISEHEFK	SFMBT1	371	Q9UHJ3
FVRDHLPDLKPEPAV	PIPOX	301	Q9P0Z9
PHFEERQPLPTGLQK	VPS33A	521	Q96AX1
HDLFPSLIKNLDPVP	USP34	426	Q70CQ2
ILDFPQHVSPSKDIR	THOP1	81	P52888
LHLLNKESPPEVFIE	ZFYVE26	2191	Q68DK2
QFTVPLLEPHLDPEA	PPP1R1A	11	Q13522
IIELHKQFRPPITQE	TRRAP	136	Q9Y4A5
PEQHPKDKPSFVRAR	UNC45A	621	Q9H3U1
NELDRSVVKEHPPRP	TPCN2	401	Q8NHX9
FPKEREVLIPPHEVF	ART5	216	Q96L15
TANAKPIPRTPDHEI	MYOT	136	Q9UBF9
IDFVPRQEPPKIHLD	MYBPC3	636	Q14896