Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribosomal protein S6 kinase activity

RPS6KA6 RPS6KA3

7.36e-057382GO:0004711
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

NIPAL1 TRPV3 PANX1 SLC5A8 NDUFA9 ANO8 SCN7A

4.99e-04758387GO:0015318
GeneOntologyMolecularFunctiontransporter activity

STARD3 NIPAL1 MFSD14A TRPV3 PANX1 SLC5A8 NDUFA9 ANO8 SCN7A

5.60e-041289389GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

NIPAL1 TRPV3 PANX1 SLC5A8 NDUFA9 ANO8 SCN7A

6.52e-04793387GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

NIPAL1 TRPV3 PANX1 SLC5A8 NDUFA9 SCN7A

1.10e-03627386GO:0022890
GeneOntologyMolecularFunctiontransmembrane transporter activity

NIPAL1 MFSD14A TRPV3 PANX1 SLC5A8 NDUFA9 ANO8 SCN7A

1.45e-031180388GO:0022857
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

NIPAL1 TRPV3 PANX1 SLC5A8 NDUFA9 SCN7A

1.47e-03664386GO:0008324
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

RPS6KA6 CRPPA ATR PARP14 HCK RPS6KA3 DOLK

1.74e-03938387GO:0016772
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

NIPAL1 TRPV3 PANX1 SLC5A8 SCN7A

1.79e-03465385GO:0046873
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

ACER3 ADA2 VNN2

2.68e-03146383GO:0016810
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPV3 PANX1 SLC5A8 ANO8 SCN7A

3.05e-03526385GO:0022803
DomainNPIP

NPIPB3 NPIPB5 NPIPB13

2.78e-0614383IPR009443
DomainRibosomal_S6_kinase_II

RPS6KA6 RPS6KA3

6.02e-056382IPR016239
DomainARM-like

ATR DOCK8 TARBP1 XPOT

2.14e-03270384IPR011989
DomainPkinase_C

RPS6KA6 RPS6KA3

2.57e-0337382IPR017892
DomainPkinase_C

RPS6KA6 RPS6KA3

3.30e-0342382PF00433
DomainARM-type_fold

ATR DOCK8 TARBP1 XPOT

4.84e-03339384IPR016024
DomainAGC-kinase_C

RPS6KA6 RPS6KA3

5.79e-0356382IPR000961
DomainAGC_KINASE_CTER

RPS6KA6 RPS6KA3

5.79e-0356382PS51285
DomainS_TK_X

RPS6KA6 RPS6KA3

5.79e-0356382SM00133
DomainGPCR_Rhodpsn_7TM

OR4P4 GPR65 GPR22 OR12D2 GPR132

1.10e-02670385IPR017452
Domain7tm_1

OR4P4 GPR65 GPR22 OR12D2 GPR132

1.15e-02677385PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4P4 GPR65 GPR22 OR12D2 GPR132

1.21e-02685385PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4P4 GPR65 GPR22 OR12D2 GPR132

1.25e-02691385PS50262
DomainGPCR_Rhodpsn

OR4P4 GPR65 GPR22 OR12D2 GPR132

1.26e-02692385IPR000276
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

RPS6KA6 RPS6KA3

3.79e-055282MM15108
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

RPS6KA6 RPS6KA3

5.68e-056282M47936
PathwayREACTOME_RSK_ACTIVATION

RPS6KA6 RPS6KA3

7.94e-057282M27369
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

RPS6KA6 RPS6KA3

3.93e-0415282MM15103
PathwayREACTOME_RHOJ_GTPASE_CYCLE

DOCK8 OPHN1

4.49e-0416282MM15605
PathwayREACTOME_NICOTINAMIDE_SALVAGING

SLC5A8 PARP14

6.37e-0419282M27094
PathwayREACTOME_NICOTINAMIDE_SALVAGING

SLC5A8 PARP14

6.37e-0419282MM14774
Pubmed

Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells.

GPR65 GPR132

4.48e-06343215665078
Pubmed

Divergent origins and concerted expansion of two segmental duplications on chromosome 16.

NPIPB3 NPIPB5

4.48e-06343211948212
Pubmed

Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors.

GPR65 GPR132

8.94e-06443232948783
Pubmed

Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis.

RPS6KA6 RPS6KA3

8.94e-06443212711546
Pubmed

The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.

RPS6KA6 RPS6KA3

1.49e-05543237068088
Pubmed

RSK2 is a modulator of craniofacial development.

RPS6KA6 RPS6KA3

1.49e-05543224416220
Pubmed

Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation.

RPS6KA6 RPS6KA3

1.49e-05543211160957
Pubmed

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.

RPS6KA6 RPS6KA3

2.23e-05643212832467
Pubmed

Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor.

GPR65 GPR132

2.23e-05643215927955
Pubmed

Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees.

RPS6KA3 OPHN1

6.68e-051043212777533
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

MFSD14A PROM1 PANX1 ADA2 FAM210B

1.85e-0443043516303743
Pubmed

5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.

ATR XPOT

5.14e-042743223027611
Pubmed

Systematic identification of pathological lamin A interactors.

STARD3 TMEM218 ZDHHC15 HCK

7.93e-0433743424623722
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

RPS6KA6 PANX1 RPS6KA3

1.03e-0316043331678930
Cytoband16p12.2

NPIPB3 NPIPB4 NPIPB5

5.82e-063743316p12.2
CytobandEnsembl 112 genes in cytogenetic band chr16p12

NPIPB3 NPIPB4 NPIPB5

5.71e-04172433chr16p12
Cytoband16p11.2

NPIPB13 NPIPB12 NPIPB11

7.74e-0419143316p11.2
CytobandEnsembl 112 genes in cytogenetic band chr16p11

NPIPB13 NPIPB12 NPIPB11

2.27e-03278433chr16p11
GeneFamilyX-linked mental retardation|Angiotensin receptors

ZDHHC15 RPS6KA3 OPHN1

4.04e-0553233103
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA6 RPS6KA3

8.45e-05112321156
GeneFamilyG protein-coupled receptors, Class A orphans

GPR65 GPR22 GPR132

1.29e-0478233262
ToppCellPND01-03-samps-Myeloid-Granulocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GPR65 DOCK8 GPR132 HCK

1.29e-051494347bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCellPND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GPR65 DOCK8 GPR132 HCK

1.29e-0514943450f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCellControl-Myeloid-Neutrophils-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 DOCK8 VNN2 HCK

1.43e-05153434e3630f2b10f33092a3b6a63dba3a39fbdecbc7bd
ToppCellControl-Myeloid-Neutrophils|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 DOCK8 VNN2 HCK

1.43e-05153434c33d63b2d1a220bc428e776b157b23faa43ea8ca
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR65 PARP14 GPR132 HCK

1.71e-0516043418954241e11309ecb0f3ca87897eadcb20dc8eca
ToppCelldroplet-Lung-nan-21m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK LRRC9

1.71e-051604344738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCelldroplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK LRRC9

1.71e-051604340b8151037b28f52a21918856a1e9336e8d5edb90
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACER3 GPR132 HCK LRRC9

1.88e-05164434cd0794f84dfd346807e2d803723718b7f22e9232
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACER3 GPR132 HCK LRRC9

1.88e-0516443412251a49fd4af32d4edb58046245548c260cf04b
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRPPA ZDHHC15 ATR ANO8

1.93e-051654348c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADA2 DOCK8 GPR132 HCK

2.07e-051684342dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCellfacs-Heart-RA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 ACER3 DOCK8 HCK

2.21e-0517143415fedb078d93ac4b7fd2945870b50a718f665487
ToppCellfacs-Heart-RA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 ACER3 DOCK8 HCK

2.21e-05171434467f53033f172905e653d85aaa6751a00e5d9e10
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PANX1 GPR65 DOCK8 GPR132

2.21e-05171434c60313b045cb77c0923ddb81bbd1a654aa1087c5
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte-Alox5+_lymphocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NIPAL1 GPR65 GPR132 LRRC9

2.53e-05177434b7cfa3776f58377e35830780650d236b5cceecee
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PANX1 ADA2 GPR132 HCK

2.53e-05177434cdad5a2f672a7f07c05669bfcaf1ec74defd3de7
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NIPAL1 GPR65 GPR132 LRRC9

2.53e-051774341730e640986e50943bd781b7d949bcc5b7c12dde
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PANX1 ADA2 GPR132 HCK

2.53e-05177434991ae76bb615392d84aeb89886148fa42c1c649c
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PANX1 ADA2 GPR132 HCK

2.65e-05179434dc03b9045510eb1bb934329646bb92dd06890ce9
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PANX1 ADA2 GPR132 HCK

2.65e-05179434330c1326ba93bb8f32559ee1cc40e357cc44ad8d
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

2.65e-051794349fc44637c9a7551fd47b8533e45a9c199e164a95
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PANX1 ADA2 GPR132 HCK

2.83e-05182434d5d6bc16458bc665e7ad6669040d79f73f640044
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PANX1 ADA2 GPR132 HCK

2.83e-051824340b59ead4bb4486c7ec2ee90b94ee3a09905612c5
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

2.89e-0518343424679153b654c148dbd572e9013c0a6e58718ada
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

2.95e-05184434315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR65 DOCK8 GPR132 HCK

3.01e-05185434e592c27f711d13bfc6546893acaab4c8600b0be1
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.08e-05186434fc6e591089c87a66653c8e552be9c0fe0c82ecd5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADA2 DOCK8 GPR132 HCK

3.21e-05188434239bec13476dd43bebc2c6eba8d1fe35f2744673
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ACER3 ADA2 DOCK8 HCK

3.27e-05189434c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.27e-05189434911bedfda2ae032bc8f18ee408d16926cda8ccc2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR65 DOCK8 GPR132 RPS6KA3

3.27e-05189434c38157c8cf5c0c1f560011ef5cc5892a049ee2b7
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 VNN2 HCK

3.34e-05190434b7ce76931edc6734b80ddbb2fca23b098a8c1352
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.34e-05190434eda2923e930e1094412088fd79c1e6a3b7db3b11
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.41e-05191434a5ee4d72b2311c8fa98ff73adc2499debb2014f1
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.41e-0519143403e1ac489e918c7affc1cdc09fb3eb255bcf80e5
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.41e-0519143479c83a710aa17fc06f286e4ea2011ed9e30e3bc6
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.48e-05192434b204ef6e05170855259b902829a1700094eb9159
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.63e-05194434a062100ea6cd512a108f9036c259e0cd0f458563
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.70e-051954346c354c38ee2965d37152ffdc86ba929ba2049c6a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADA2 DOCK8 VNN2 HCK

3.70e-051954341d58585557bf8e9ce4d514e128d3a902b526331d
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.70e-051954345f46f9aca1c7f76416e861aa94d24fc1d6266113
ToppCellCOVID-19-lung-Macrophage_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

GPR65 PARP14 DOCK8 HCK

3.77e-051964341b7928f4eee94d4bb6ea410bab68a471dba12979
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR65 DOCK8 VNN2 HCK

3.77e-051964344354ee481053e7b02e8c0bb16ea4377566ef2b53
ToppCellbackground-Kupffer_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ACER3 ADA2 DOCK8 HCK

3.85e-051974348b45c7ecc18d188abc8c172d9bf881c95617a46a
ToppCellControl_saline-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|Control_saline / Treatment groups by lineage, cell group, cell type

GPR65 ADA2 DOCK8 HCK

3.93e-05198434c15ab0660a6de445a83396cf70860ea39868914d
ToppCellImmune|World / Lineage, Cell type, age group and donor

ACER3 ADA2 DOCK8 HCK

3.93e-0519843465681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellPCW_13-14-Hematologic_Myeloid|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GPR65 DOCK8 GPR132 HCK

3.93e-05198434d42fce8e547dc97f3cf144ab65483a1b11ace267
ToppCellControl_saline-Hematopoietic_Myeloid-Monocytes,_Macrophages|Control_saline / Treatment groups by lineage, cell group, cell type

GPR65 ADA2 DOCK8 HCK

3.93e-05198434684f2dd5db889f118b5218ee23733cc1361272c2
ToppCellControl_saline-Hematopoietic_Myeloid|Control_saline / Treatment groups by lineage, cell group, cell type

GPR65 ADA2 DOCK8 HCK

4.00e-051994346be92062cce049a4c98f7311f2500bf1468fc267
ToppCellCOVID-19-kidney-Epithelial_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

GPR65 ADA2 HCK

2.11e-04120433e17c85d41c781a29dec7e03a8b0637dccb4346bc
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR22 GPR132

3.12e-04137433587a369b148bb2600c06db39298feddfc99cb6ad
ToppCelldroplet-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK

3.53e-041434334d11d53330a9197275a8851e1bbf55a113715a09
ToppCelldroplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK

3.53e-041434338b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCellLPS_only-Myeloid-Dendritic_cells-mDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADA2 DOCK8 GPR132

3.83e-0414743326bd9d89e2e7b841cc18030bb7cebb642b987183
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP61 PTCHD3 LRRC9

3.91e-04148433d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFAP61 PTCHD3 LRRC9

3.91e-04148433c8e93b87212f55774223caa385859c566fa1981f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NPIPB4 PARP14 GPR132

4.06e-041504336c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACER3 GPR132 HCK

4.06e-04150433b37f538ca5f976b509efe35dc81115b72b227084
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACER3 GPR132 HCK

4.06e-041504332c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCellfacs-MAT-Fat-24m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 ACER3 HCK

4.47e-04155433d0c1608f8f6b6f4174e51d610501c707cba5e015
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

CFAP61 ACER3 HCK

4.56e-041564331a0e081284a99c1b345990775015b8a2fa469496
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPR65 ACER3 DOCK8

4.64e-04157433904cd98ae85ed6459e0663f077ac462842bf12df
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK8 GPR132 HCK

4.73e-04158433121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCelldroplet-Bladder-Unstain-18m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

4.82e-04159433a80b4637a74bcc6f213d584aba2c727a983eedb3
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

4.82e-0415943389b5e895e95cdd654edd471bde9b6887939b3503
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPR65 GPR132 HCK

4.91e-041604336329b0f02f9509086e563c2ed762a8ec693883b5
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK8 GPR132 HCK

4.91e-04160433bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NIPAL1 PROM1 PTCHD3

4.91e-041604331d3abf5e30318774bd1862a44a32850f47b79f4c
ToppCellfacs-Pancreas-Endocrine-24m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.00e-041614335680939068b5a63aa1064202b4ee8847156c8ccd
ToppCellfacs-Pancreas-Endocrine-24m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.00e-041614337a19f3c652534e93a15c0a9692a67397a70d6ad4
ToppCellfacs-Pancreas-Endocrine-24m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.00e-04161433e713f4165b8deb98652cab59bfdd53df41a5d177
ToppCelldroplet-Bladder-nan-3m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.09e-041624330cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCelldroplet-Bladder-nan-3m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.18e-041634332f32a9ab0230fdca98ffa7fd59397301d50e4f30
ToppCelldroplet-Bladder-nan-3m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.18e-041634336c2967dee563295febe2adabf503d095cb911ccf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 GPR132 SCN7A

5.18e-041634338028636632c168dc50731d0ebecaf88a70daf81d
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.27e-04164433f3684d029ca58b782e3e87f79e56069b42b22fdd
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.27e-04164433b1a6f56207cb0fbd3f99225d4a7354a17aa26362
ToppCellfacs-Pancreas-Endocrine-3m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.37e-041654332e9e703c3f89784a47ed40f799d2aa86eba6cc9a
ToppCellfacs-Heart-LA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 DOCK8 HCK

5.37e-04165433be7e18d798e81e4b0f3080054aa222c6913e350b
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK

5.37e-04165433e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM218 TARBP1 ANO8

5.37e-041654330edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Pancreas-Endocrine-3m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.37e-041654334d51eb992670bce164eea29b540877b4d567953c
ToppCellfacs-Pancreas-Endocrine-3m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.37e-041654338715ea74d02e9b7cd05fa1b4896b353078544678
ToppCellfacs-Heart-LA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 DOCK8 HCK

5.37e-04165433941a5b95164eaea47c3e6376e358f94c15b98312
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.37e-041654338a3cfec76cc7c5a309d582becd1aef4261b7f4e1
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM218 TARBP1 ANO8

5.37e-04165433fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCellsevere-HSPC|severe / disease stage, cell group and cell class

PROM1 CRPPA ZDHHC15

5.37e-04165433acd837d88ad3786c263f74651a6c0e02fa2fa2c5
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK

5.37e-041654330fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.46e-04166433e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NDUFA9 DOCK8 HCK

5.46e-04166433063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCelldroplet-Lung-LUNG-1m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK

5.46e-04166433dd5944101ef58a9a29aa3eb5c17690119572b8f1
ToppCelldroplet-Bladder-nan-24m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.46e-041664339951ed7b5492b949b8db49969308f919d89468e5
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER3 GPR132 HCK

5.46e-041664338e5e8de51b4dacdadaa5a08279df30b5c7ed3628
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NDUFA9 DOCK8 HCK

5.46e-04166433417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCellfacs-Heart-LA-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 DOCK8 HCK

5.46e-0416643319ec59f0a43d4eb5b4cc7bcd6480ada7f469054b
ToppCellfacs-Lung-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK8 GPR132 HCK

5.46e-041664337bf7c2854cf7d85b3ae07256bbe86ae9184d6b57
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

NDUFA9 DOCK8 HCK

5.46e-04166433f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCelldroplet-Bladder-nan-24m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 GPR132 HCK

5.46e-04166433eadc88669710895f43544d81e08c97248488f19b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR65 DOCK8 GPR132

5.56e-0416743341675d15919104c9e20cd97620fe636f3ff33fa9
ToppCellControl-Lymphocytic_B|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPR65 DOCK8 HCK

5.56e-04167433956da82394fd6a9f45fc2031796f12cc889542cd
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA6 RPS6KA3

9.67e-064382DOID:3783 (implicated_via_orthology)
DiseaseLarge cell carcinoma of lung

RPS6KA6 ATR

7.82e-0432382C0345958
DiseaseCombined immunodeficiency

ADA2 DOCK8

1.28e-0341382C0494261
Diseaseocular hypertension, response to triamcinolone acetonide

CRPPA CFAP61

1.83e-0349382EFO_0006954, EFO_1001069

Protein segments in the cluster

PeptideGeneStartEntry
IVTTVYLKVKEPIFH

ACER3

131

Q9NUN7
VYKAVPELHFIFLIV

CFAP61

126

Q8NHU2
VVVLEHFALLLKYLI

ANO8

846

Q9HCE9
LHVIIAFPTSYKVVI

NPIPB3

61

Q92617
IVVEILIEHFGKIYL

OPHN1

551

O60890
LYPVVVVSVHFLDFK

CRPPA

366

A4D126
LHVIIAFPTSYKVVI

NPIPB12

61

F8W0I5
ENYRLFVIFHLPELK

LRRC9

1041

Q6ZRR7
TKFFVVFRHPVLIFI

NOL11

156

Q9H8H0
ARKYFHLIVVATYIP

DOLK

336

Q9UPQ8
ILVEVNHPFIVKLHY

RPS6KA3

121

P51812
HVIVVVLFFAPALFI

OR4P4

241

Q8NGL7
VVAYAIHKLFAPVRI

FAM210B

151

Q96KR6
LHVIIAFPTSYKVVI

NPIPB5

61

A8MRT5
ILVEVNHPFIVKLHY

RPS6KA6

126

Q9UK32
VVILFYAPVLFTYIH

OR12D2

246

P58182
LKVYEILPTFDVLHF

PANX1

306

Q96RD7
LHVIIAFPTSYKVVI

NPIPB4

61

C9JG80
LVKYIFAVAHRLFLP

NDUFA9

276

Q16795
FIFYIFHVELKELPI

MFSD14A

391

Q96MC6
LHIIIAFPTSYKVVI

NPIPB11

61

E5RHQ5
VKVVIFLPQVLDVFY

PARP14

1366

Q460N5
DFKVTIYLLPHILVY

ATR

1521

Q13535
HAVVTKEPIYIITEF

HCK

321

P08631
VYKLVIPILEAHREF

DOCK8

1751

Q8NF50
FVETHPEFIGIKIIY

ADA2

276

Q9NZK5
YHLLVQIPIFFFTVV

GPR22

211

Q99680
YKHPLVFVLLAVLVL

NIPAL1

271

Q6NVV3
VTVIPVFHLAYILII

PTCHD3

381

Q3KNS1
LHVIIAFPTSYKVVI

NPIPB13

61

A6NJU9
IFILVGIVHYPVFQT

GPR132

166

Q9UNW8
PIGILFELVHIFLYV

PROM1

51

O43490
VVISAEVFLPVFYKL

SLC5A8

96

Q8N695
VYTIEVPFHGKTFIL

STARD3

271

Q14849
FIAAVYEHAVILPNK

VNN2

26

O95498
DLDHYLFPIVYIFVI

GPR65

11

Q8IYL9
VVRYEKFFTVEPQHI

XPOT

506

O43592
KVILHDVLKFLFVYI

TRPV3

581

Q8NET8
TIKVLVHPFFQLFIL

SCN7A

111

Q01118
FLVLIHYVLEPIYAK

TMEM218

96

A2RU14
VIHFLELYETKILPF

TARBP1

396

Q13395
PIYIHVFSALIVIIA

TEX29

56

Q8N6K0
PAEKVIYLILYHAIF

ZDHHC15

51

Q96MV8