Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal aortic valve cusp morphology

TRIM45 ADAM19 MATR3 CYFIP2

3.30e-0647314MP:0010595
MousePhenoabnormal aortic valve morphology

TRIM45 ADAM19 MATR3 CYFIP2

1.83e-0572314MP:0002747
MousePhenoabnormal heart left ventricle outflow tract morphology

TRIM45 ADAM19 MATR3 CYFIP2

1.83e-0572314MP:0010429
MousePhenobicuspid aortic valve

TRIM45 MATR3 CYFIP2

2.20e-0525313MP:0010484
MousePhenoabnormal heart valve morphology

TRIM45 ADAM19 TNS1 MATR3 CYFIP2

2.70e-05163315MP:0000285
MousePhenoabnormal heart ventricle outflow tract morphology

TRIM45 ADAM19 MATR3 CYFIP2

5.70e-0596314MP:0010224
MousePhenoabnormal semilunar valve morphology

TRIM45 ADAM19 MATR3 CYFIP2

5.94e-0597314MP:0002746
DomainDisintegrin_CS

ADAM19 ADAM12

4.26e-0416362IPR018358
DomainMetalloPept_cat_dom

ADAM19 ADAM12 MMP28

5.06e-0481363IPR024079
Domain-

ADAM19 ADAM12 MMP28

5.06e-04813633.40.390.10
DomainADAM_CR

ADAM19 ADAM12

5.42e-0418362PF08516
Domain-

ADAM19 ADAM12

6.72e-04203624.10.70.10
DomainDISIN

ADAM19 ADAM12

7.41e-0421362SM00050
DomainDisintegrin

ADAM19 ADAM12

7.41e-0421362PF00200
DomainZINC_PROTEASE

ADAM19 ADAM12 MMP28

8.82e-0498363PS00142
DomainADAM_Cys-rich

ADAM19 ADAM12

1.23e-0327362IPR006586
DomainACR

ADAM19 ADAM12

1.23e-0327362SM00608
DomainPeptidase_M12B_N

ADAM19 ADAM12

2.56e-0339362IPR002870
DomainPep_M12B_propep

ADAM19 ADAM12

2.56e-0339362PF01562
DomainDISINTEGRIN_1

ADAM19 ADAM12

2.69e-0340362PS00427
DomainADAM_MEPRO

ADAM19 ADAM12

2.69e-0340362PS50215
DomainDISINTEGRIN_2

ADAM19 ADAM12

2.69e-0340362PS50214
DomainReprolysin

ADAM19 ADAM12

2.69e-0340362PF01421
DomainPeptidase_M12B

ADAM19 ADAM12

2.69e-0340362IPR001590
DomainCYSTEINE_SWITCH

ADAM19 MMP28

2.83e-0341362PS00546
DomainDisintegrin_dom

ADAM19 ADAM12

2.83e-0341362IPR001762
DomainPept_M10_metallopeptidase

ADAM19 MMP28

3.10e-0343362IPR001818
DomainSushi

CR1 HP

4.51e-0352362PF00084
DomainCCP

CR1 HP

4.85e-0354362SM00032
DomainSUSHI

CR1 HP

5.21e-0356362PS50923
DomainSushi_SCR_CCP_dom

CR1 HP

5.39e-0357362IPR000436
DomainEGF_extracell

ADAM19 ADAM12

5.96e-0360362IPR013111
DomainEGF_2

ADAM19 ADAM12

5.96e-0360362PF07974
Pubmed

A metalloprotease-disintegrin participating in myoblast fusion.

ADAM19 ADAM12

3.30e-0633727566181
Pubmed

Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo.

ADAM19 ADAM12

3.30e-0633729622634
Pubmed

Cigarette smoke augments MUC5AC production via the TLR3-EGFR pathway in airway epithelial cells.

MUC5AC TLR3

3.30e-06337226100173
Pubmed

Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication.

STING1 TLR3

3.30e-06337231896590
Pubmed

Immunohistochemical analysis of NKX2.2, ETV4, and BCOR in a large series of genetically confirmed Ewing sarcoma family of tumors.

ETV4 BCOR

3.30e-06337228864350
Pubmed

Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.

ADAM19 ADAM12

3.30e-0633729461614
Pubmed

Rhinovirus-induced major airway mucin production involves a novel TLR3-EGFR-dependent pathway.

MUC5AC TLR3

3.30e-06337218978302
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ADGRA1 CAMSAP1 BCOR TNS1 ZEB2 MATR3 CYFIP2 SPATA13

6.35e-0696337828671696
Pubmed

SARS-CoV-2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG-I/MDA-5-MAVS, TLR3-TRIF, and cGAS-STING signaling pathways.

STING1 TLR3

6.60e-06437233913550
Pubmed

Selective modulation of integrin-mediated cell migration by distinct ADAM family members.

ADAM19 ADAM12

6.60e-06437216079176
Pubmed

Pattern recognition receptor-mediated innate immune responses in seminal vesicle epithelial cell and their impacts on cellular function†.

STING1 TLR3

6.60e-06437231350848
Pubmed

The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells.

ADAM19 ADAM12

6.60e-06437212615925
Pubmed

Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2.

ADAM19 ADAM12

1.10e-05537215936750
Pubmed

Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer.

AHSG HP

1.10e-05537221953030
Pubmed

Toll-like receptor 3 signal augments radiation-induced tumor growth retardation in a murine model.

STING1 TLR3

1.65e-05637229465830
Pubmed

Increased CD40 Expression Enhances Early STING-Mediated Type I Interferon Response and Host Survival in a Rodent Malaria Model.

STING1 TLR3

2.30e-05737227716849
Pubmed

Deletion of the Isg15 gene results in up-regulation of decidual cell survival genes and down-regulation of adhesion genes: implication for regulation by IL-1beta.

ADGRA1 ADAM12

2.30e-05737220660068
Pubmed

Porous silicon microparticle potentiates anti-tumor immunity by enhancing cross-presentation and inducing type I interferon response.

STING1 TLR3

2.30e-05737225937283
Pubmed

Canonical transforming growth factor-β signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29.

ADAM19 ADAM12

3.07e-05837224103556
Pubmed

Different ADAMs have distinct influences on Kit ligand processing: phorbol-ester-stimulated ectodomain shedding of Kitl1 by ADAM17 is reduced by ADAM19.

ADAM19 ADAM12

3.07e-05837217344430
Pubmed

An innate antiviral pathway acting before interferons at epithelial surfaces.

STING1 TLR3

3.07e-05837226595890
Pubmed

Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.

ADAM19 ADAM12

3.07e-05837210527948
Pubmed

Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection.

STING1 TLR3

3.95e-05937230923196
Pubmed

Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection.

STING1 TLR3

6.02e-051137220107183
Pubmed

Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses.

STING1 TLR3

6.02e-051137230699352
Pubmed

Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner.

STING1 TLR3

7.22e-051237229632368
Pubmed

Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity.

STING1 CYFIP2

7.22e-051237232277911
Pubmed

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia.

STING1 TLR3

7.22e-051237228111081
Pubmed

Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality.

STING1 TLR3

1.31e-041637227793594
Pubmed

TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.

STING1 TLR3

1.86e-041937228400473
Pubmed

Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.

ADAM19 ADAM12

1.86e-041937215063736
Pubmed

Interferon inducible GBPs restrict Burkholderia thailandensis motility induced cell-cell fusion.

STING1 TLR3

2.07e-042037232150572
Pubmed

Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis.

VEGFD MUC5AC

2.28e-042137219710174
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

BCOR ZEB2 PPM1G

2.59e-0411637330804394
Pubmed

Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.

STING1 MATR3

2.75e-042337219240791
Pubmed

Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.

STING1 TLR3

2.99e-042437234526512
Pubmed

Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.

ADAM19 ADAM12

2.99e-042437225825872
Pubmed

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.

STING1 TLR3

4.09e-042837228410990
Pubmed

Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.

STING1 TLR3

4.39e-042937234678150
Pubmed

Microphthalmia/Anophthalmia/Coloboma Spectrum – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

STRA6 BCOR

6.05e-043437220301552
Pubmed

Multiple roles of epithelial heparan sulfate in stomach morphogenesis.

ETV4 MUC5AC

6.41e-043537229700203
Pubmed

Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development.

ETV4 MUC5AC

6.78e-043637228859094
Pubmed

The human plasma proteome: a nonredundant list developed by combination of four separate sources.

AHSG ETV4 HP

7.24e-0416537314718574
Pubmed

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

AHSG HP

8.80e-044137216740002
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

DCBLD1 BCOR MATR3

9.31e-0418037335198878
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CAMSAP1 BCOR ZEB2

9.92e-0418437332908313
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

AHSG HP

1.01e-034437231273033
InteractionADAM8 interactions

ADAM19 STING1 ADAM12

9.30e-0711373int:ADAM8
Cytoband5q31.2

STING1 MATR3

2.36e-04283725q31.2
Cytoband5q33.3

ADAM19 CYFIP2

3.91e-04363725q33.3
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM19 ADAM12

5.33e-042723247
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CR1 HP

2.37e-03572321179
CoexpressionPEREZ_TP53_TARGETS

AHSG ABHD15 STING1 BCOR ADAM12 TNS1 MUC5AC MMP28 CYFIP2 TLR3

4.41e-0612013710M4391
CoexpressionGSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_UP

AHSG DCBLD1 BCOR TNS1 PIP4P1

8.79e-06200375M8488
CoexpressionTABULA_MURIS_SENIS_HEART_ATRIAL_MYOCYTE_AGEING

ZNF775 SZT2 MATR3 PPM1G

4.75e-05142374MM3703
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

PGGHG VEGFD TNS1 ZEB2

1.02e-05164374519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD15 VEGFD TNS1 MUC5AC

1.15e-051693747962165cab84af73d20b56eb70b1ed87c94025ef
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ADAM19 TNS1 CYFIP2

1.41e-051783740f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIM45 STING1 PGGHG PIP4P1

1.41e-05178374c87945146b2734141f07b39d268e0d8086ee0364
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ADAM19 TNS1 CYFIP2

1.41e-05178374d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ADAM19 TNS1 CYFIP2

1.41e-05178374b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VEGFD ADAM12 TNS1 ZEB2

1.44e-05179374b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCBLD1 FMO5 PGGHG MMP28

1.57e-051833743ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAM12 ZEB2 CYFIP2 SPATA13

1.79e-0518937446c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

VEGFD ADAM12 TNS1 ZEB2

1.86e-051913743379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAM12 HP ZEB2 CYFIP2

1.86e-0519137478ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAM12 ZEB2 CYFIP2 SPATA13

1.94e-05193374035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

ADAM19 CR1 HP MATR3

2.06e-0519637415397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM19 STING1 ZEB2 PPM1G

2.10e-051973741ca06d6d288cb58a6e8062ebc01831e58ee5be4b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAM19 SZT2 TNS1 ZEB2

2.19e-05199374379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRIM45 ABHD15 STING1 TLR3

2.23e-05200374aafe594c88710f8c53d59667cdac5035e08f5511
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRIM45 ABHD15 STING1 TLR3

2.23e-05200374a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHSG ETV4 MATR3

7.16e-0597373442201932dc318846dc45f6c753e30b0d9a69f73
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHSG ETV4 MATR3

7.84e-05100373c50714a0819a40917d7a360623220576473f52ad
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Entopeduncular / BrainAtlas - Mouse McCarroll V32

STRA6 VEGFD MMP28

7.84e-05100373b4e8f3cbb5023d2227f43e683967ec2f848648f1
ToppCellMild/Remission-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PGGHG MATR3 PIP4P1

1.38e-0412137368940a552233d255b90ce5a081339c0d9d46ab02
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Intermediate_Fibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

VEGFD ADAM12 TNS1

1.99e-04137373dd5364a1002650d21e0c83d8c701b5f7b09d1c19
ToppCellMild/Remission-B_naive-1|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PGGHG MATR3 PIP4P1

2.26e-04143373bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCellControl-B_intermediate-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PGGHG MATR3 PIP4P1

2.30e-04144373984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell390C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DOCK3 NBAS FMO5

2.70e-04152373595afcfa8b161e291fcaf2afc7336bac9b6fae0f
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAM19 CYFIP2 TLR3

2.86e-041553739f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellControl-B_naive-1|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PGGHG MATR3 PIP4P1

2.86e-041553730a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCellPND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HP CYFIP2 SPATA13

2.91e-04156373166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCellPND07-28-samps-Myeloid-Granulocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

HP CYFIP2 SPATA13

2.91e-041563735e1c5a7c9293b886920739cf766521df7f69726c
ToppCellfacs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 HP CYFIP2

2.97e-041573739d4308312301cb922f156a7b6aededc9e1c62807
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 BCOR HP

3.02e-04158373d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 BCOR HP

3.02e-04158373ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VEGFD TNS1 MUC5AC

3.20e-04161373b19f82dd98a3064581793711bb70373f18abecd9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK3 ADAM19 ADAM12

3.20e-04161373580153e131247e6ec12a1a920f050a0a763e7e87
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEGFD MMP28 TLR3

3.20e-04161373441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP CYFIP2 SPATA13

3.37e-0416437315d52666e5150e7c34b1f641a937fb2d5e8aaf8a
ToppCellfacs-Lung-EPCAM-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP CYFIP2 SPATA13

3.37e-04164373d622f0d8d8bad48dfdf160ec63c545df192637a9
ToppCellICU-NoSEP-Lymphocyte-T_NK-MAIT|ICU-NoSEP / Disease, Lineage and Cell Type

DCBLD1 ZNF775 ADAM12

3.49e-04166373d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAM19 STRA6 CAMSAP1

3.49e-041663730590e404f45afce90e20f93f90a3def83949c66b
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 ETV4 STRA6

3.56e-041673731adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 ETV4 STRA6

3.56e-04167373743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HP CYFIP2 SPATA13

3.62e-04168373c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HP CYFIP2 SPATA13

3.62e-04168373c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

ETV4 STRA6 HP

3.68e-04169373150c08c7b1dc0f46173a7b8f6a3fc70d82906c0d
ToppCellLPS-IL1RA-Lymphocytic_B|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM19 CR1 CYFIP2

3.75e-0417037356284fbfd1e53f67c8c0b7fba64505a4002adba2
ToppCelldroplet-Fat-Scat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM12 HP ZEB2

3.75e-04170373de722bea7527d6ad11b69f8e9589638f52854beb
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCOR CYFIP2 SPATA13

3.75e-041703738e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCOR CYFIP2 SPATA13

3.75e-04170373f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM19 CR1 CYFIP2

3.75e-0417037392e0873f618b2fa60c4d555b10f234d5cbcf3325
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM19 CR1 CYFIP2

3.75e-04170373c181991f933b779f99afc3782f292306f209e2ac
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ABHD15 BCOR

3.81e-04171373d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PGGHG MATR3 PIP4P1

3.81e-04171373d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV4 ZEB2 ZNF689

3.88e-04172373f814b6134ad608015765399d54cc1e5e1873ed34
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV4 ZEB2 ZNF689

3.88e-041723731f335ccb92b22d0412954e8fc3af212f96410b67
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV4 ZEB2 ZNF689

3.88e-04172373bb96c896d125e10b71e94e2bdad243899045af5c
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 MMP28 TLR3

3.88e-04172373a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABHD15 ZEB2 CYFIP2

3.88e-04172373f3c16a62eba1ed190318beee131c71c5150b266a
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD15 VEGFD ADAM12

3.88e-0417237330916a902c151907745756d14327e24adc34afef
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAM19 MMP28 TLR3

3.94e-0417337370c0c13febd28b395fb3171ec8d7fbbc6c9d4eb7
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 ADAM12 TLR3

4.08e-041753730801cccec6915aefc135262fc74580280fd51aa5
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VEGFD TNS1 ZEB2

4.08e-04175373282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 ADAM12 TLR3

4.08e-0417537309163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CR1 HP ZEB2

4.08e-041753731cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCellCF-Myeloid-Neutrophil|Myeloid / Disease state, Lineage and Cell class

CR1 PGGHG CYFIP2

4.08e-041753738020c3a34f77e68e8149f87481fb1dddd2ac675e
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|normal_Lymph_Node / Location, Cell class and cell subclass

ZNF775 ADAM19 ZEB2

4.15e-04176373476794ef75ce5ab732d78cfeb4944e2f841e3e92
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

ADAM19 CR1 CYFIP2

4.15e-04176373d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ABHD15 STING1

4.22e-041773737853430fb0d1a18d835e8956777e0616c5d7d412
ToppCellfacs-Skin-Anagen-3m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ABHD15 STING1

4.22e-04177373395f005f019aabb18738d3a10a04c37f216deda3
ToppCellfacs-Skin-Anagen-3m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHSG ABHD15 STING1

4.22e-041773739a5bf67a801826d094f679dd2189b62296c9694f
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

ABHD15 ADAM19 CYFIP2

4.29e-041783738d9e28492e1f157bac3308aa947fd864ca16d277
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HP CYFIP2 SPATA13

4.29e-04178373a1f2c134bb7596f678fb4cc11405c374d926ea0f
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STING1 HP ZEB2

4.36e-04179373fa58fa0901eadb170e3d2facb2a3d8c5e624329a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STING1 HP ZEB2

4.36e-0417937366afd54428e6dcadc3e341faecfde42be4fb5905
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ETV4 ADAM12 SPATA13

4.36e-041793735787ffba96918db80256ced076a455a84ba01384
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HP CYFIP2 SPATA13

4.43e-0418037305cce7e3c13dd3e3b70aaad841097be51cfadad3
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

VEGFD HP TNS1

4.43e-04180373adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB2 PPM1G SPATA13

4.50e-0418137312ff56fa2949c8d53360cdf2cacfd326e65b54aa
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

VEGFD TNS1 ZEB2

4.57e-04182373ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell(00)_Basal-(0)_uninjured|(00)_Basal / shred by cell type and Timepoint

HP TNS1 CYFIP2

4.57e-04182373c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

ZEB2 MATR3 CYFIP2

4.65e-04183373f593a89b0aa8fffdfa403769916facfd30358521
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

DCBLD1 NBAS ADAM12

4.65e-04183373d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZEB2 MATR3 SPATA13

4.65e-04183373278064c9f0582463b83bf156d34e77f60187613b
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

CR1 PGGHG CYFIP2

4.65e-04183373da43827952e6fdee2ce94648c316182f272b321c
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ETV4 ADAM12 ZEB2

4.72e-041843737aa245b73e10fd73d292e822de6b72920aa12355
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CR1 PGGHG HP

4.72e-041843737ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 ADAM19 ADAM12

4.72e-04184373d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 ADAM19 TNS1

4.79e-04185373e58a009aaf342be019a909747b1895d5987d4daf
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

NBAS ADAM19 ZEB2

4.79e-04185373a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRA6 ADAM12 CYFIP2

4.79e-04185373bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

STING1 CR1 ADAM12

4.79e-04185373c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADAM19 VEGFD TNS1

4.87e-04186373cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellChildren_(3_yrs)-Immune-B_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM19 CR1 CYFIP2

4.87e-04186373aa576748921a318798b911a611f05319b95e8d5e
ToppCellASK452-Immune-Mast_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ADAM12 ZEB2 SPATA13

5.02e-04188373840215e16cff90f821f776186284eafcf2350690
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

VEGFD TNS1 ZEB2

5.02e-041883733f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

VEGFD TNS1 ZEB2

5.10e-041893730c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellnormal_Pleural_Fluid-T/NK_cells-Treg|normal_Pleural_Fluid / Location, Cell class and cell subclass

STING1 ADAM12 PPM1G

5.18e-04190373632b9541371483d25948b6f033863c49f38e3603
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAM19 CR1 ZEB2

5.18e-0419037357800d807785b9d539b47945a0a74631f5e88a06
ToppCellwk_20-22-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ABHD15 ZEB2 CYFIP2

5.18e-04190373f49ceda3622cf079cffde9c9a9e3d0380c571d39
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Th17_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ADAM19 ADAM12 ZEB2

5.18e-04190373693b223f6b94a46d935fbcb02d7a27340ce43154
ToppCellT_cells-Effector_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ADAM19 STING1 ADAM12

5.18e-041903731af91fe0ee2c924e12f4db93c793e7af475d8f80
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

STRA6 TNS1 MMP28

1.37e-0450223GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_8
DiseaseT-cell immunoglobulin and mucin domain 1 measurement

ADAM19 CYFIP2

3.03e-057362EFO_0010812
DiseaseMalaria

CR1 HP

2.71e-0420362C0024530
Diseasecomplex trait

DCBLD1 NBAS ZNF689 PPM1G

3.25e-04271364EFO_0010578
Diseaseasthma (is_marker_for)

HP MUC5AC TLR3

4.90e-04126363DOID:2841 (is_marker_for)
DiseaseFEV/FEC ratio

DCBLD1 ADAM19 ADAM12 TNS1 ZEB2 CYFIP2 SPATA13

6.15e-041228367EFO_0004713
DiseaseDevelopmental delay (disorder)

NBAS SZT2

9.38e-0437362C0424605
Diseasecolitis (biomarker_via_orthology)

HP TLR3

1.21e-0342362DOID:0060180 (biomarker_via_orthology)
DiseaseCongenital Heart Defects

STRA6 ZEB2

1.33e-0344362C0018798
DiseaseDisorder of eye

SPATA7 STRA6 BCOR

2.19e-03212363C0015397

Protein segments in the cluster

PeptideGeneStartEntry
IYRSEHLKPPPGNCG

ADAM19

161

Q9H013
PHLHGCLQGRTKPPY

ADGRA1

411

Q86SQ6
RPPRGFQPCQAHLGH

ADAM12

756

O43184
LSLHGKGPVYPHPVL

BCOR

671

Q6W2J9
PPVQLPAEGCHRHYL

CAMSAP1

386

Q5T5Y3
HHGCPLVSPRLQPFG

ABHD15

196

Q6UXT9
SRKPPLPYHHGEQCL

ETV4

111

P43268
FHGLLPKGYPHLCSI

MATR3

281

P43243
LKISGGPHISYPPLH

MAGEA12

291

P43365
GCPKPPEIAHGYVEH

HP

91

P00738
PHPYLPVLACSGLDH

DCAF8L2

521

P0C7V8
PPLPPRCHVHGKSYR

MUC5AC

1231

P98088
ALPQPKAPGYICHGL

PGGHG

266

Q32M88
PKICRLPRHEYGSPG

CYFIP2

981

Q96F07
PPAGIAHKGKPHYRV

NBAS

1151

A2RRP1
KGPPHLHYRRPYGCA

DOCK3

306

Q8IZD9
AACPHPPKIQNGHYI

CR1

1846

P17927
CHSAPHGPGLIYRQP

AHSG

16

P02765
GPCTPIHYRVQGPGK

FMO5

466

P49326
PHYIPGYTGHCPLLR

FAM166B

16

A8MTA8
YRVPGPQPGHKHSLS

DCBLD1

621

Q8N8Z6
NPALKCLSPGGHPTY

FLAD1

556

Q8NFF5
YCKRIINLGPVHPGP

PIP4P1

146

Q86T03
LRGHKGHQCLSPPLP

CCDC159

256

P0C7I6
PQGRRPETQGPKYCH

MMP28

311

Q9H239
PIPKHLHTPGSNGRY

SZT2

591

Q5T011
LHPSIPCPRGHGAQK

STING1

6

Q86WV6
GYSRIGKPILCPVHP

TRIM45

181

Q9H8W5
LLTRYGQNCHKGPPH

PPM1G

156

O15355
HCIYTPQPGFHLPLK

STRA6

281

Q9BX79
GKSKGYNRCPVAPPH

SPATA13

591

Q96N96
LCNTPPHYHGFPVRL

TLR3

676

O15455
NPGGRPKEPHLHSYK

TNS1

936

Q9HBL0
PHPCPHCGRGFRQKQ

ZNF775

336

Q96BV0
SVLPRYGPPCLFKGH

SPATA7

11

Q9P0W8
GSPLAKGLHPLQPCH

nan

371

Q3C1V9
IHQRIHTGEKPYPCP

ZNF689

306

Q96CS4
HTGCKCLPTAPRHPY

VEGFD

186

O43915
PGPIPLHQHERYLCK

ZEB2

591

O60315