Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	AP2A1 AP2A2	1.01e-05	2	60	2	2.60.40.1030
Domain	AP2_complex_asu	AP2A1 AP2A2	1.01e-05	2	60	2	IPR017104
Domain	Clathrin_a-adaptin_app_sub_C	AP2A1 AP2A2	1.01e-05	2	60	2	IPR003164
Domain	Clathrin_a-adaptin_app_Ig-like	AP2A1 AP2A2	1.01e-05	2	60	2	IPR013038
Domain	Alpha_adaptin_C	AP2A1 AP2A2	1.01e-05	2	60	2	PF02296
Domain	ARM-type_fold	SF3B1 AP2A1 AP2A2 PIK3C2G PIK3CD ARMC5 EIF2B5 LTN1	1.22e-05	339	60	8	IPR016024
Domain	-	AP2A1 AP2A2	6.06e-05	4	60	2	3.30.310.30
Domain	Clathrin_a/coatomer_app_sub_C	AP2A1 AP2A2	6.06e-05	4	60	2	IPR015873
Domain	PI3K_Ras-bd_dom	PIK3C2G PIK3CD	2.11e-04	7	60	2	IPR000341
Domain	PI3K_rbd	PIK3C2G PIK3CD	2.11e-04	7	60	2	PF00794
Domain	PI3K_RBD	PIK3C2G PIK3CD	2.11e-04	7	60	2	PS51546
Domain	PI3K_rbd	PIK3C2G PIK3CD	2.11e-04	7	60	2	SM00144
Domain	PI3K_C2_dom	PIK3C2G PIK3CD	2.81e-04	8	60	2	IPR002420
Domain	Coatomer/calthrin_app_sub_C	AP2A1 AP2A2	2.81e-04	8	60	2	IPR009028
Domain	PI3K_C2	PIK3C2G PIK3CD	2.81e-04	8	60	2	PF00792
Domain	PI3K_C2	PIK3C2G PIK3CD	2.81e-04	8	60	2	PS51547
Domain	PI3K_C2	PIK3C2G PIK3CD	2.81e-04	8	60	2	SM00142
Domain	PI3Ka	PIK3C2G PIK3CD	3.60e-04	9	60	2	PF00613
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP2A1 AP2A2	3.60e-04	9	60	2	IPR008152
Domain	Alpha_adaptinC2	AP2A1 AP2A2	3.60e-04	9	60	2	PF02883
Domain	Alpha_adaptinC2	AP2A1 AP2A2	3.60e-04	9	60	2	SM00809
Domain	-	PIK3C2G PIK3CD	3.60e-04	9	60	2	1.25.40.70
Domain	PI3Ka	PIK3C2G PIK3CD	3.60e-04	9	60	2	SM00145
Domain	PIK_HELICAL	PIK3C2G PIK3CD	4.49e-04	10	60	2	PS51545
Domain	PI_Kinase	PIK3C2G PIK3CD	4.49e-04	10	60	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2G PIK3CD	4.49e-04	10	60	2	IPR001263
Domain	Coatomer/clathrin_app_Ig-like	AP2A1 AP2A2	6.56e-04	12	60	2	IPR013041
Domain	Clathrin/coatomer_adapt-like_N	AP2A1 AP2A2	1.04e-03	15	60	2	IPR002553
Domain	Adaptin_N	AP2A1 AP2A2	1.04e-03	15	60	2	PF01602
Domain	PI3/4_kinase_CS	PIK3C2G PIK3CD	1.04e-03	15	60	2	IPR018936
Domain	-	PIK3C2G PIK3CD	1.18e-03	16	60	2	1.10.1070.11
Domain	PI3Kc	PIK3C2G PIK3CD	1.18e-03	16	60	2	SM00146
Domain	-	IL1RAPL1 NTM L1CAM ITGB4 MADCAM1 BTN2A1 OPCML IFNAR2	1.21e-03	663	60	8	2.60.40.10
Domain	PI3/4_kinase_cat_dom	PIK3C2G PIK3CD	1.50e-03	18	60	2	IPR000403
Domain	PI3_PI4_kinase	PIK3C2G PIK3CD	1.50e-03	18	60	2	PF00454
Domain	PI3_4_KINASE_3	PIK3C2G PIK3CD	1.50e-03	18	60	2	PS50290
Domain	PI3_4_KINASE_1	PIK3C2G PIK3CD	1.50e-03	18	60	2	PS00915
Domain	PI3_4_KINASE_2	PIK3C2G PIK3CD	1.50e-03	18	60	2	PS00916
Domain	ARM-like	SF3B1 AP2A1 AP2A2 ARMC5 LTN1	1.74e-03	270	60	5	IPR011989
Domain	Ig-like_fold	IL1RAPL1 NTM L1CAM ITGB4 MADCAM1 BTN2A1 OPCML IFNAR2	1.81e-03	706	60	8	IPR013783
Domain	IG	IL1RAPL1 NTM L1CAM MADCAM1 BTN2A1 OPCML	2.27e-03	421	60	6	SM00409
Domain	Ig_sub	IL1RAPL1 NTM L1CAM MADCAM1 BTN2A1 OPCML	2.27e-03	421	60	6	IPR003599
Domain	Ig_I-set	IL1RAPL1 NTM L1CAM OPCML	3.25e-03	190	60	4	IPR013098
Domain	I-set	IL1RAPL1 NTM L1CAM OPCML	3.25e-03	190	60	4	PF07679
Domain	IG_LIKE	IL1RAPL1 NTM L1CAM MADCAM1 BTN2A1 OPCML	4.83e-03	491	60	6	PS50835
Domain	Ig-like_dom	IL1RAPL1 NTM L1CAM MADCAM1 BTN2A1 OPCML	5.42e-03	503	60	6	IPR007110
Domain	-	SF3B1 AP2A1 AP2A2 ARMC5	5.63e-03	222	60	4	1.25.10.10
Domain	RGS	RGSL1 RGS22	5.64e-03	35	60	2	PF00615
Domain	RGS	RGSL1 RGS22	5.96e-03	36	60	2	PS50132
Domain	IGc2	IL1RAPL1 NTM L1CAM OPCML	6.87e-03	235	60	4	SM00408
Pubmed	Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance.	AP2A1 AP2A2 L1CAM	3.12e-06	16	63	3	24305805
Pubmed	Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.	NOX1 PIK3C2G PIK3CD	3.12e-06	16	63	3	21029719
Pubmed	Gene-targeted deletion of OPCML and Neurotrimin in mice does not yield congenital heart defects.	NTM OPCML	3.23e-06	2	63	2	24616287
Pubmed	Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).	AP2A1 AP2A2	3.23e-06	2	63	2	2564002
Pubmed	Cloning of neurotrimin defines a new subfamily of differentially expressed neural cell adhesion molecules.	NTM OPCML	3.23e-06	2	63	2	7891157
Pubmed	Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.	AP2A1 AP2A2	3.23e-06	2	63	2	12036598
Pubmed	OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.	NTM OPCML	3.23e-06	2	63	2	12819783
Pubmed	Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.	AP2A1 AP2A2	9.68e-06	3	63	2	35014951
Pubmed	A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.	AP2A1 AP2A2	9.68e-06	3	63	2	18032517
Pubmed	AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.	AP2A1 AP2A2	9.68e-06	3	63	2	22262466
Pubmed	Immunocytochemical colocalization of clusterin in apoptotic photoreceptor cells in retinal degeneration slow rds mutant mouse retinas.	PRPH2 OCA2	9.68e-06	3	63	2	8769098
Pubmed	Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.	AP2A1 AP2A2	9.68e-06	3	63	2	26269175
Pubmed	Prostate-specific antigen and 17-hydroxylase polymorphic genotypes in patients with prostate cancer and benign prostatic hyperplasia.	PSAP CYP17A1	9.68e-06	3	63	2	17961073
Pubmed	A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.	AP2A1 AP2A2	9.68e-06	3	63	2	19129443
Pubmed	Interaction of Shc with adaptor protein adaptins.	AP2A1 AP2A2	9.68e-06	3	63	2	8617812
Pubmed	The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein.	AP2A1 AP2A2	9.68e-06	3	63	2	8662627
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	HTR2A L1CAM SLC6A5 GRM4 SERPINA6 CHRNB4	1.76e-05	300	63	6	19086053
Pubmed	The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.	AP2A1 AP2A2	1.93e-05	4	63	2	12646615
Pubmed	Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.	AP2A1 AP2A2	1.93e-05	4	63	2	20500056
Pubmed	CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth.	AP2A1 L1CAM	1.93e-05	4	63	2	12942088
Pubmed	Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function.	AP2A1 OCA2	1.93e-05	4	63	2	19116314
Pubmed	Association and colocalization of Eps15 with adaptor protein-2 and clathrin.	AP2A1 AP2A2	1.93e-05	4	63	2	9049247
Pubmed	Endotoxin-induced vascular endothelial cell migration is dependent on TLR4/NF-κB pathway, NAD(P)H oxidase activation, and transient receptor potential melastatin 7 calcium channel activity.	NOX1 TRPM7	1.93e-05	4	63	2	25130439
Pubmed	Weak Molecular Interactions in Clathrin-Mediated Endocytosis.	AP2A1 AP2A2	3.22e-05	5	63	2	29184887
Pubmed	A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.	AP2A1 AP2A2	3.22e-05	5	63	2	17108326
Pubmed	AQP3-Dependent PI3K/Akt Modulation in Breast Cancer Cells.	PIK3CD AQP3	3.22e-05	5	63	2	37175840
Pubmed	Spatiotemporal expression of IgLON family members in the developing mouse nervous system.	NTM OPCML	3.22e-05	5	63	2	34599206
Pubmed	Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.	AP2A1 AP2A2	3.22e-05	5	63	2	9723620
Pubmed	Interaction of HIV-1 Gag with the clathrin-associated adaptor AP-2.	AP2A1 AP2A2	3.22e-05	5	63	2	16139856
Pubmed	TRPM7 ion channels are required for sustained phosphoinositide 3-kinase signaling in lymphocytes.	TRPM7 PIK3CD	3.22e-05	5	63	2	18590694
Pubmed	Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.	AP2A1 AP2A2	3.22e-05	5	63	2	31671891
Pubmed	Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis.	AP2A1 AP2A2	3.22e-05	5	63	2	15941406
Pubmed	Calcyon, a mammalian specific NEEP21 family member, interacts with adaptor protein complex 3 (AP-3) and regulates targeting of AP-3 cargoes.	AP2A1 AP2A2	4.82e-05	6	63	2	22650988
Pubmed	Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium.	AP2A1 AP2A2	4.82e-05	6	63	2	22713487
Pubmed	The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites.	AP2A1 AP2A2	4.82e-05	6	63	2	12121421
Pubmed	Clathrin.	AP2A1 AP2A2	4.82e-05	6	63	2	10966473
Pubmed	Molecular architecture and functional model of the endocytic AP2 complex.	AP2A1 AP2A2	4.82e-05	6	63	2	12086608
Pubmed	HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses.	AP2A1 AP2A2	4.82e-05	6	63	2	15020715
Pubmed	An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia.	PSAP PIK3C2G	4.82e-05	6	63	2	17893707
Pubmed	Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.	NTM L1CAM OPCML	6.18e-05	42	63	3	15146195
Pubmed	Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine.	AP2A1 AP2A2	6.74e-05	7	63	2	20351096
Pubmed	Clathrin interacts specifically with amphiphysin and is displaced by dynamin.	AP2A1 AP2A2	6.74e-05	7	63	2	9280305
Pubmed	Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein.	AP2A1 AP2A2	6.74e-05	7	63	2	7671305
Pubmed	Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta.	AP2A1 AP2A2	6.74e-05	7	63	2	16103193
Pubmed	Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.	AP2A1 AP2A2	6.74e-05	7	63	2	23676497
Pubmed	Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.	AP2A1 AP2A2	8.98e-05	8	63	2	2014052
Pubmed	Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice.	AP2A1 AP2A2	8.98e-05	8	63	2	11879655
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	SF3B1 PSAP GLB1 AP2A2 WDR11 HACD3 GEMIN2 ACIN1	1.04e-04	809	63	8	32129710
Pubmed	Accessory protein recruitment motifs in clathrin-mediated endocytosis.	AP2A1 AP2A2	1.15e-04	9	63	2	12057195
Pubmed	Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance.	PIK3CD L1CAM	1.15e-04	9	63	2	18367611
Pubmed	Doublecortin interacts with mu subunits of clathrin adaptor complexes in the developing nervous system.	AP2A1 AP2A2	1.15e-04	9	63	2	11591131
Pubmed	CIN85 interacting proteins in B cells-specific role for SHIP-1.	AP2A1 AP2A2 PIK3CD	1.32e-04	54	63	3	21725061
Pubmed	The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.	PIK3C2G PIK3CD	1.44e-04	10	63	2	8636073
Pubmed	CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.	AP2A1 AP2A2	1.44e-04	10	63	2	25898166
Pubmed	HIV-1 Nef-induced down-regulation of MHC class I requires AP-1 and clathrin but not PACS-1 and is impeded by AP-2.	AP2A1 AP2A2	1.44e-04	10	63	2	17581864
Pubmed	Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.	PIK3C2G PIK3CD	1.44e-04	10	63	2	8798481
Pubmed	Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm.	L1CAM DICER1	1.44e-04	10	63	2	20386732
Pubmed	Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.	PIK3C2G PIK3CD	1.44e-04	10	63	2	9247029
Pubmed	Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.	HTR2A SERPINA6	1.44e-04	10	63	2	20403506
Pubmed	Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees.	IL1RAPL1 L1CAM	1.44e-04	10	63	2	12777533
Pubmed	MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.	AP2A1 GEMIN2 LTN1 DICER1	1.62e-04	150	63	4	22678362
Pubmed	Mapping the Genetic Landscape of Human Cells.	SF3B1 TRPM7 GEMIN2 EIF2B5 LTN1 DICER1	1.67e-04	451	63	6	30033366
Pubmed	Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.	AP2A1 AP2A2	1.76e-04	11	63	2	31388001
Pubmed	HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.	PIK3C2G PIK3CD	1.76e-04	11	63	2	16081599
Pubmed	HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.	PIK3C2G PIK3CD	1.76e-04	11	63	2	9708406
Pubmed	HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.	PIK3C2G PIK3CD	1.76e-04	11	63	2	10985305
Pubmed	Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.	PIK3C2G PIK3CD	1.76e-04	11	63	2	12584329
Pubmed	HIV-1 Assembly at the Plasma Membrane: Gag Trafficking and Localization.	AP2A1 AP2A2	1.76e-04	11	63	2	19802344
Pubmed	Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.	PIK3C2G PIK3CD	1.76e-04	11	63	2	9808187
Pubmed	Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.	PIK3C2G PIK3CD	2.11e-04	12	63	2	14602571
Pubmed	Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.	PIK3C2G PIK3CD	2.11e-04	12	63	2	16514418
Pubmed	HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.	PIK3C2G PIK3CD	2.11e-04	12	63	2	10208934
Pubmed	Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.	PIK3C2G PIK3CD	2.11e-04	12	63	2	12077252
Pubmed	Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.	PIK3C2G PIK3CD	2.11e-04	12	63	2	9341793
Pubmed	Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.	PIK3C2G PIK3CD	2.11e-04	12	63	2	12551992
Pubmed	HIV-1 Nef in macrophage-mediated disease pathogenesis.	PIK3C2G PIK3CD	2.49e-04	13	63	2	23215766
Pubmed	Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.	PIK3C2G PIK3CD	2.49e-04	13	63	2	9394803
Pubmed	Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.	SLC6A5 GRM4	2.49e-04	13	63	2	20859245
Pubmed	Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins.	AP2A1 AP2A2	2.49e-04	13	63	2	9882340
Pubmed	Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease.	AP2A2 CSMD1	2.90e-04	14	63	2	25241909
Pubmed	Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor.	AP2A1 AP2A2	2.90e-04	14	63	2	11157096
Pubmed	Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.	PIK3C2G PIK3CD	2.90e-04	14	63	2	17157319
Pubmed	Redundant and nonredundant organismal functions of EPS15 and EPS15L1.	AP2A1 AP2A2	2.90e-04	14	63	2	30692166
Pubmed	Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse.	L1CAM CDH8	2.90e-04	14	63	2	20847152
Pubmed	APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development.	AP2A1 AP2A2	2.90e-04	14	63	2	29262337
Pubmed	LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.	AP2A1 AP2A2	3.34e-04	15	63	2	21307259
Pubmed	HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.	PIK3C2G PIK3CD	3.34e-04	15	63	2	18854243
Pubmed	Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.	NTM OCA2	3.34e-04	15	63	2	23548203
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	AP2A1 AP2A2 EIF2B5 LTN1	3.47e-04	183	63	4	23956138
Pubmed	Proteome-wide characterization of N-glycosylation events by diagonal chromatography.	CES1 SERPINA6 IFNAR2	3.77e-04	77	63	3	16944957
Pubmed	HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.	AP2A1 AP2A2	3.81e-04	16	63	2	21762802
Pubmed	HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.	PIK3C2G PIK3CD	3.81e-04	16	63	2	16524887
Pubmed	PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.	AP2A1 AP2A2	3.81e-04	16	63	2	16055064
Pubmed	HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.	PIK3C2G PIK3CD	3.81e-04	16	63	2	11289809
Pubmed	Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.	PIK3C2G PIK3CD	3.81e-04	16	63	2	20019835
Pubmed	Genome-wide association of body fat distribution in African ancestry populations suggests new loci.	CSMD1 OPCML	3.81e-04	16	63	2	23966867
Pubmed	Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders.	PIK3C2G PIK3CD	3.81e-04	16	63	2	20818790
Pubmed	Synergistic cooperation between methamphetamine and HIV-1 gsp120 through the P13K/Akt pathway induces IL-6 but not IL-8 expression in astrocytes.	PIK3C2G PIK3CD	4.32e-04	17	63	2	23251686
Pubmed	Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.	PIK3C2G PIK3CD	4.32e-04	17	63	2	12960231
Pubmed	Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.	PIK3C2G PIK3CD	4.32e-04	17	63	2	18453587
Cytoband	11q25	NTM OPCML	5.90e-04	26	63	2	11q25
Cytoband	Ensembl 112 genes in cytogenetic band chr11q25	NTM OPCML	8.40e-04	31	63	2	chr11q25
GeneFamily	I-set domain containing\|IgLON cell adhesion molecules	NTM OPCML	6.30e-05	5	46	2	1052
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2G PIK3CD	1.76e-04	8	46	2	831
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	IL1RAPL1 NTM L1CAM OPCML	7.39e-04	161	46	4	593
Coexpression	YOSHIMURA_MAPK8_TARGETS_UP	HTR2A PIK3C2G CES1 PIK3CD CYP17A1 RGS22 L1CAM AQP3 ITGB4 MADCAM1 CDH8 KCNH3 DNAH1	7.57e-06	1281	62	13	M1884
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	IL1RAPL1 NTM CSMD1 CDH8 OPCML	3.08e-06	159	63	5	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B PIK3C2G RGS22 CSMD1 DNAH1	6.28e-06	184	63	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B PIK3C2G RGS22 CSMD1 DNAH1	6.28e-06	184	63	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B PIK3C2G RGS22 CSMD1 DNAH1	6.28e-06	184	63	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PSAP HACD3 PIK3C2G L1CAM AQP3	7.72e-06	192	63	5	967122c53af25b8f19a8411b4553d764c8d51c4d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSAP HACD3 PIK3C2G L1CAM AQP3	7.92e-06	193	63	5	e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSAP HACD3 PIK3C2G L1CAM AQP3	8.97e-06	198	63	5	0d9d401190792fd61434f1b82548253187d805f0
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	IL1RAPL1 NTM CSMD1 OPCML	5.46e-05	146	63	4	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	KLK11 NOX1 NPW MADCAM1	6.89e-05	155	63	4	a16e3a72badafa78a3efc4f4ab62396f0ce99d1e
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	KLK11 NOX1 NPW MADCAM1	8.78e-05	165	63	4	ebd668e87e5961a124d1d6fc25d1f03e4af05cd4
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	IL1RAPL1 NTM L1CAM ITGB4	8.78e-05	165	63	4	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KLK11 GRM4 AQP3 ITGB4	9.41e-05	168	63	4	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IL1RAPL1 NTM L1CAM ITGB4	9.41e-05	168	63	4	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	IL1RAPL1 NTM L1CAM ITGB4	9.41e-05	168	63	4	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KLK11 GRM4 AQP3 ITGB4	9.63e-05	169	63	4	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	IL1RAPL1 NTM L1CAM ITGB4	1.05e-04	173	63	4	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Sema3e-Excitatory_Neuron.Sc17a7.Sema3e-Onecut2_(Layer_6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PRPH2 NPW MADCAM1	1.23e-04	68	63	3	5af7170acc5e4503375d84472d538e7f5dc92e1d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KLK11 WDR11 AQP3 ITGB4	1.31e-04	183	63	4	bbf27d2f4369031fadacacd6c432c06b1ec5abdb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IL1RAPL1 PSAP PIK3C2G L1CAM	1.34e-04	184	63	4	9690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RGSL1 HTR2A GPR63	1.34e-04	70	63	3	be300c0447735aba89df4c3082b81eb5abf22770
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RGSL1 HTR2A GPR63	1.34e-04	70	63	3	2121ba6a0beb2a8fdc589ff1063e7d8c2c3c68f6
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RGSL1 HTR2A GPR63	1.34e-04	70	63	3	cd6bca68fe52f451716fc8c0b1745984bc9ec057
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLK11 NTM GPR63 ITGB4	1.36e-04	185	63	4	f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL1RAPL1 NTM GRM4 CDH8	1.39e-04	186	63	4	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.42e-04	187	63	4	b7689e7f6511920cd2beff27389555fddf685f61
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLK11 RGS22 HCFC1R1 NPW	1.45e-04	188	63	4	00c5259bcb83218b7d44f4d585d9b68ef49763ab
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RGSL1 L1CAM CSMD1 ITGB4	1.45e-04	188	63	4	502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL1RAPL1 L1CAM CSMD1 ITGB4	1.48e-04	189	63	4	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PSAP PIK3C2G L1CAM AQP3	1.54e-04	191	63	4	7235a4d1601c88a2c8af571a2c04ab56d32f1b9a
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.54e-04	191	63	4	65083daf317f66556dc047eb19297dcbe9c70299
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSAP PIK3C2G L1CAM AQP3	1.54e-04	191	63	4	0a0719a0a49ae0099d61e22585ac74c10c24b4a2
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.57e-04	192	63	4	d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLK11 RGS22 HCFC1R1 NPW	1.57e-04	192	63	4	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.57e-04	192	63	4	9e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.57e-04	192	63	4	3d777d07878269b87ec7e1f06489cae7c989d633
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.60e-04	193	63	4	d994b2f2707877288f88cab7cd6002ef91962c50
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	CES1 SLC6A5 OCA2 ITGB4	1.60e-04	193	63	4	6e9912f5444c591e698b9a7ffa3e9fc3d8ee57b0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.60e-04	193	63	4	5da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.64e-04	194	63	4	be869e186386d03ebb670971dd24fa656b4b0edf
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G L1CAM AQP3 ITGB4	1.64e-04	194	63	4	4579b4a44f7c731553a284843c296866027d7c0e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.64e-04	194	63	4	4d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.67e-04	195	63	4	e94bac6a5c788ee160d7feaf2a3c512a3691f995
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.67e-04	195	63	4	0ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3C2G L1CAM AQP3 ITGB4	1.67e-04	195	63	4	3d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.70e-04	196	63	4	cd8c22c6f52f068a33525723108d6b5b23fe822d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.70e-04	196	63	4	6ee8dcc5cd643747e20d23b9556c17f7c102b19c
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.70e-04	196	63	4	142fd80ff74979cc2f9088fc3fcbfed374afb973
ToppCell	Bronchial-NucSeq-Stromal-Schwann\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL1RAPL1 HTR2A L1CAM ITGB4	1.70e-04	196	63	4	a90c76d9c57a4491b94a321ba541b792ec5d8e83
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_nonmyelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL1RAPL1 HTR2A L1CAM ITGB4	1.74e-04	197	63	4	4a7ff67bb0754e034e6f2a1bd34cde86ee3ef899
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HACD3 PIK3C2G L1CAM AQP3	1.80e-04	199	63	4	4003e8d9e1bbead5e1169418429b7eea523da320
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-4\|TCGA-Skin / Sample_Type by Project: Shred V9	G6PC3 ARMC5 HCFC1R1 OCA2	1.80e-04	199	63	4	bbda9060918797303984ca2b64e9bb73fdacd0c4
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NPW CSMD1 AQP3 ITGB4	1.84e-04	200	63	4	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NPW CSMD1 AQP3 ITGB4	1.84e-04	200	63	4	ac9ead34afa14067171833f5c277eaf06db7b02e
Drug	ITdU	HTR2A GLB1 G6PC3 PIK3C2G CES1 PIK3CD CYP17A1 SERPINA6 AQP3	9.29e-08	292	62	9	CID000000076
Disease	MASA syndrome (implicated_via_orthology)	TRPM7 L1CAM	8.20e-05	7	59	2	DOID:0060246 (implicated_via_orthology)
Disease	Schizophrenia	PRODH2 HTR2A WDR11 SLC6A5 CSMD1 GRM4 DICER1 OPCML	3.58e-04	883	59	8	C0036341
Disease	respiratory symptom measurement, COVID-19	IL1RAPL1 RGS22 CSMD1	4.45e-04	74	59	3	EFO_0007939, MONDO_0100096
Disease	nicotine withdrawal measurement	AP2A2 CSMD1	1.34e-03	27	59	2	EFO_0009362
Disease	blood manganese measurement	CSMD1 OPCML	1.34e-03	27	59	2	EFO_0007581
Disease	colorectal cancer (is_implicated_in)	CES1 PIK3CD DICER1	1.85e-03	121	59	3	DOID:9256 (is_implicated_in)
Disease	aggressive behaviour measurement, childhood aggressive behaviour measurement	NTM CSMD1	1.88e-03	32	59	2	EFO_0007663, EFO_0007826
Disease	R-warfarin measurement	KLK11 HTR2A NTM RAB3GAP2	1.96e-03	265	59	4	EFO_0803324
Disease	severe acute respiratory syndrome, COVID-19	IL1RAPL1 HACD3 PIK3C2G SELENOI CSMD1	1.99e-03	447	59	5	EFO_0000694, MONDO_0100096

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLWLPPAIYKSACKI	CHRNB4	141	P30926
RKTKAAPCIYWLPLT	ACIN1	1216	Q9UKV3
LLWKSYPLVCIAKEL	CES1	381	P23141
YCSAWKPLLLIVPLR	ATG4A	216	Q8WYN0
YPILKDCIWLITVPP	CSMD1	2166	Q96PZ7
WARLPLCLLLSLYGP	GRM4	11	Q14833
LYGYRWPLPSKLCAV	HTR2A	136	P28223
WLSVKLLRLLQCYPP	AP2A1	256	O95782
LPFICRKPSLWRRLL	ARMC5	661	Q96C12
SLWRKAVCLPSILYR	DICER1	1046	Q9UPY3
WLSVKLLRLLQCYPP	AP2A2	256	O94973
ALLVLRLCAWPPLVT	PRODH2	116	Q9UF12
LVCFPLLRLLYWNRK	OCA2	521	Q04671
RLCSVPLDKEKWYPL	PIK3C2G	1426	O75747
ELILYRKSGLPFWCL	KCNH3	96	Q9ULD8
GVLPYWPRIFCKISL	LTN1	101	O94822
KWILAPVILYICERI	NOX1	271	Q9Y5S8
ELLARLPPTLCTWLK	RAB3GAP2	1326	Q9H2M9
LLLLALPTYHLWKRC	MADCAM1	331	Q13477
LGRWLYALLACLEKP	GEMIN2	211	O14893
LWIPLYPLGCLAEAV	HACD3	281	Q9P035
YLFLPWKCLVVVSLR	NTM	6	Q9P121
LLLLLLPLPSGAWYK	NPW	21	Q8N729
KYTLWPCLVLALVPW	G6PC3	316	Q9BUM1
LLVILRPGPYICAEW	GLB1	116	P16278
RYCALLLPLLKAWSP	EIF2B5	616	Q13144
YLLPQLRKQLPWFCL	PCNX3	1096	Q9H6A9
LLPTREPEILWYKEC	IL1RAPL1	171	Q9NZN1
PRWLLTAAHCLKPRY	KLK11	86	Q9UBX7
RYVWPLLLCSPCLLI	L1CAM	6	P32004
LLPLLALLLLLCWKY	ITGB4	721	P16144
WIGYICLRNSLPKVL	IFNAR2	266	P48551
YLFLPWKCLVVVSLR	OPCML	6	Q14982
CWLRKLPPLLKPYEE	DNAH1	2021	Q9P2D7
MYCLQWLLPVLLIPK	BLCAP	1	P62952
ALLLLTLAYLFWPKR	CYP17A1	6	P05093
IRLECISRGWYPKPL	BTN2A1	161	Q7KYR7
RCPTLNWLLVPLFLV	SELENOI	316	Q9C0D9
LLWLCYLKSALNPLI	GPR63	356	Q9BZJ6
PCSELLLWRYPGSLI	HCFC1R1	96	Q9NWW0
LIILWITLPPCIYMA	CDH8	16	P55286
MPLLLYTCLLWLPTS	SERPINA6	1	P08185
LLPRWPLAKLKLYHA	CYB561D2	146	O14569
WCVLKPGVLLIYKTP	OSBPL5	146	Q9H0X9
CYWEKLVYLLRPPVE	GARIN3	166	Q8TC56
VRWPSLLAPYQACLI	PARS2	361	Q7L3T8
YKGLLTWLEKCRLPF	RGSL1	61	A5PLK6
KCWKPRPLSIYIILG	TMEM225B	61	P0DP42
IEYPGEIRWPLALCL	SLC6A5	386	Q9Y345
EVLKPLLLYWAPRFC	RGS22	496	Q8NE09
KVRLSLWGVLCPVYI	SLC66A1L	116	A1A4F0
CFLAREPWIKLPIYT	AQP3	91	Q92482
LILPCYDLKLPIWAN	C10orf126	16	Q8N4M7
PWLKPYLAICVLFNI	PRPH2	96	P23942
KPYLPQICGTVLWRL	SF3B1	926	O75533
YLLCSWPELPVLSAL	PIK3CD	566	O00329
CKWILPILTQFTPYL	PRAMEF11	216	O60813
ILVYLEKTCDWLPKP	PSAP	86	P07602
ALFPLLPKVLQKYWC	ZBED1	596	O96006
VWCPYLLVPRASLAL	WDR11	841	Q9BZH6
FLWYLCLLPLVMPLV	PIGM	336	Q9H3S5
KRFPYPLNELLIWAC	TRPM7	616	Q96QT4
CLATKKLDLWRLPPF	USP6	1061	P35125
LWAYSCEPLRQPLLK	MYO7B	1641	Q6PIF6